BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0349.0010.p (805 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K6Z3.1 B3K6Z3_9BACI DNA topoisomerase (ATP-hydrolyzing) EC=5.9... 994 0.0 B1DMD2.1 B1DMD2_9BACL DNA topoisomerase IV, A subunit EC=5.99.1.3 963 0.0 C1PFK2.1 C1PFK2_BACCO DNA topoisomerase IV, A subunit EC=5.99.1.3 794 0.0 B7HAW9.1 B7HAW9_BACC4 DNA topoisomerase IV, A subunit EC=5.99.1.- 778 0.0 C3H448.1 C3H448_BACTU DNA topoisomerase 4 subunit A 778 0.0 >B3K6Z3.1 B3K6Z3_9BACI DNA topoisomerase (ATP-hydrolyzing) EC=5.99.1.3 Length = 584 Score = 994 bits (2570), Expect = 0.0, Method: Compositional matrix adjust. Identities = 478/571 (83%), Positives = 514/571 (90%) Query: 1 LPAFLEEVVGDRFGRYSKYIIQDRAIPDVRDGLKPVQRRILYAMYDSGNTPDKPYRKSAK 60 LPAFLEEVVGDRFGRYSKYIIQDRAIPDVRDGLKPVQRRILYAMYDSGNTPDKPYRKSAK Sbjct: 8 LPAFLEEVVGDRFGRYSKYIIQDRAIPDVRDGLKPVQRRILYAMYDSGNTPDKPYRKSAK 67 Query: 61 TVGDVMGNYHPHGDSSIYEGMVRMAQPWKMGHVLIDGHGNWGSMDDDPAAAMRYTEARLS 120 TVGDVMGNYHPHGDSSIYEGMVRMAQPWKMGHVL+DGHGNWGS DDDPAAAMRYTEARLS Sbjct: 68 TVGDVMGNYHPHGDSSIYEGMVRMAQPWKMGHVLVDGHGNWGSQDDDPAAAMRYTEARLS 127 Query: 121 PIAMEMMRDIEKRTVLFKDNFDNTAKEPVVVPSRYPNLLVNGTSGISAGFATEIPPHNLR 180 PIAME++RDIEKRTVLFKDNFDNTAKEPVV+PSRYPNLLVNG SGISAGFATEIPPHNLR Sbjct: 128 PIAMELLRDIEKRTVLFKDNFDNTAKEPVVLPSRYPNLLVNGASGISAGFATEIPPHNLR 187 Query: 181 EVIDACIAVMQKPDIALEDIMTFIKGPDFPXXXXXXXXXXXXDAYRTGKGRIYLRSKTEI 240 EVIDACIAVMQKP+I L++IMTFIKGPDFP DAYRTGKGR+YLRSKT I Sbjct: 188 EVIDACIAVMQKPEIELDEIMTFIKGPDFPTGGIIMGGEGILDAYRTGKGRVYLRSKTVI 247 Query: 241 ENLRGGKQQIVITEVPFQIVKSRLVTSMENIRLEKKIEGIAEVRDESGRDGLRIVVELKK 300 E+LRGGKQQIVITE+P+Q+VKSRLVT+MENIRLEKK+EGIAEVRDESGR+GLRIVVELKK Sbjct: 248 ESLRGGKQQIVITEIPYQVVKSRLVTAMENIRLEKKVEGIAEVRDESGREGLRIVVELKK 307 Query: 301 EADAQGILAYLLKKTDLQVTYNFNMVAIVNKSPQQLGLKAILEAYIAHQREVVTHRTQFD 360 +ADA GILAYL KKTDLQ+TYNFNMVAIVNK+PQQLGLKA+L AYI HQREVVTHRTQF+ Sbjct: 308 DADANGILAYLFKKTDLQITYNFNMVAIVNKTPQQLGLKAMLSAYIDHQREVVTHRTQFE 367 Query: 361 LEKAEDRAHVLEGLVKALNILDEVIAAIKASKNRQDAQNNLVWMFGFSERQADSILTLQL 420 LEKAEDRAHVLEGLVKALNILDEVIAAIKASKNRQDAQNNL WMFGF+ERQADSILTLQL Sbjct: 368 LEKAEDRAHVLEGLVKALNILDEVIAAIKASKNRQDAQNNLQWMFGFTERQADSILTLQL 427 Query: 421 YRLTNLEIHSLQKELDEMNARIAVLKGILESDKKLIAVIRKELIEIRDKYGIDRRSLIQG 480 YRLTNLEIHSLQKELDE+ +I L+ IL+SDKKLI VIRKELIEIR+KYGIDRRS+IQ Sbjct: 428 YRLTNLEIHSLQKELDELTKKIEGLRAILDSDKKLIGVIRKELIEIREKYGIDRRSVIQE 487 Query: 481 XXXXXXXXXXXXXNAEDVLVALSADGYIKRTGMLSFTRSGGERNASGVKEGDHIVRLMDL 540 NAEDVLV LS +GYIKRT MLSFTRSGGE +SGVKEGD+I RL ++ Sbjct: 488 EVEEIKVNLEVLVNAEDVLVTLSNEGYIKRTSMLSFTRSGGELESSGVKEGDYITRLFEV 547 Query: 541 NTRDSLLVFTRKGQYFLLPVHQIPEFKWKEP 571 NT ++LL+FT +GQYFLLPVHQ K P Sbjct: 548 NTLENLLIFTSRGQYFLLPVHQFRSTSGKMP 578 >B1DMD2.1 B1DMD2_9BACL DNA topoisomerase IV, A subunit EC=5.99.1.3 Length = 624 Score = 963 bits (2489), Expect = 0.0, Method: Compositional matrix adjust. Identities = 460/616 (74%), Positives = 529/616 (85%), Gaps = 3/616 (0%) Query: 1 LPAFLEEVVGDRFGRYSKYIIQDRAIPDVRDGLKPVQRRILYAMYDSGNTPDKPYRKSAK 60 LPA+LEEVVGDRFGRYSKYIIQDRAIPDVRDGLKPVQRRILYAMYDS NTPDKPYRKSAK Sbjct: 8 LPAYLEEVVGDRFGRYSKYIIQDRAIPDVRDGLKPVQRRILYAMYDSNNTPDKPYRKSAK 67 Query: 61 TVGDVMGNYHPHGDSSIYEGMVRMAQPWKMGHVLIDGHGNWGSMDDDPAAAMRYTEARLS 120 TVGDVMGNYHPHGDSSIYEGMVRMAQPWKMGHVLIDGHGNWGSMDDDPAAAMRYTEARLS Sbjct: 68 TVGDVMGNYHPHGDSSIYEGMVRMAQPWKMGHVLIDGHGNWGSMDDDPAAAMRYTEARLS 127 Query: 121 PIAMEMMRDIEKRTVLFKDNFDNTAKEPVVVPSRYPNLLVNGTSGISAGFATEIPPHNLR 180 PIAME++RDI+KRTV FKDNFDNT KEPVV+PSRYPNLLVNGTSGISAGFATEIPPH+LR Sbjct: 128 PIAMEILRDIDKRTVQFKDNFDNTTKEPVVLPSRYPNLLVNGTSGISAGFATEIPPHSLR 187 Query: 181 EVIDACIAVMQKPDIALEDIMTFIKGPDFPXXXXXXXXXXXXDAYRTGKGRIYLRSKTEI 240 E IDACIAVM +P++ +E++M +KGPDFP +AY TGKGRIY+RSK EI Sbjct: 188 ETIDACIAVMARPEMTVEELMGIVKGPDFPTGGIIMGEEGIREAYTTGKGRIYIRSKVEI 247 Query: 241 ENLRGGKQQIVITEVPFQIVKSRLVTSMENIRLEKKIEGIAEVRDESGRDGLRIVVELKK 300 E++RGG+QQI ITE+P+Q+VKSRLV++MENIRLEKK+EGI+EVRDESGR+GLRIVVELKK Sbjct: 248 EDVRGGRQQITITEIPYQVVKSRLVSAMENIRLEKKVEGISEVRDESGRNGLRIVVELKK 307 Query: 301 EADAQGILAYLLKKTDLQVTYNFNMVAIVNKSPQQLGLKAILEAYIAHQREVVTHRTQFD 360 EADA GILAYLLKKTDLQVTYNFNMVAIVNK+PQQLG+K IL AYI HQ+EVVTHRTQ++ Sbjct: 308 EADANGILAYLLKKTDLQVTYNFNMVAIVNKAPQQLGIKQILNAYINHQKEVVTHRTQYE 367 Query: 361 LEKAEDRAHVLEGLVKALNILDEVIAAIKASKNRQDAQNNLVWMFGFSERQADSILTLQL 420 LEKAE+RAHV+EGLVKALNILDEVIA IKASKNR DAQNNLV +GFSERQAD+ILTLQL Sbjct: 368 LEKAEERAHVVEGLVKALNILDEVIATIKASKNRADAQNNLVAKYGFSERQADAILTLQL 427 Query: 421 YRLTNLEIHSLQKELDEMNARIAVLKGILESDKKLIAVIRKELIEIRDKYGIDRRSLIQG 480 YRLTNLEI SL+KE E +IA L+ ILES+KKL+ VI+ EL EIR+KYGIDRRS I+G Sbjct: 428 YRLTNLEITSLEKEWKETQKKIAYLRSILESEKKLLGVIKDELTEIREKYGIDRRSSIRG 487 Query: 481 XXXXXXXXXXXXXNAEDVLVALSADGYIKRTGMLSFTRSGGERNASGVKEGDHIVRLMDL 540 +EDV+V LS +GY+KRT MLSFTRSGG+ +GVKEGD I + ++ Sbjct: 488 EVEELKVNLEVMVQSEDVIVTLSEEGYMKRTSMLSFTRSGGDLQTAGVKEGDAISSVYEV 547 Query: 541 NTRDSLLVFTRKGQYFLLPVHQIPEFKWKEPGTAIVNVIGLAKGDGIASILPVGNMDDPG 600 NT D+LL+FTRKGQY++LPVHQIPEFKWK+ GTA+VN++ + K D I +I+PV + + G Sbjct: 548 NTIDNLLLFTRKGQYYMLPVHQIPEFKWKDTGTAVVNIVPIPKDDSIVAIIPVKDFNLAG 607 Query: 601 ASLVFVTRKGQVKRTE 616 + F + Q + +E Sbjct: 608 S---FACIRNQTRPSE 620 >C1PFK2.1 C1PFK2_BACCO DNA topoisomerase IV, A subunit EC=5.99.1.3 Length = 815 Score = 794 bits (2050), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/764 (51%), Positives = 545/764 (71%), Gaps = 10/764 (1%) Query: 5 LEEVVGDRFGRYSKYIIQDRAIPDVRDGLKPVQRRILYAMYDSGNTPDKPYRKSAKTVGD 64 LEEV+GDRFGRYSKYIIQDRA+PD RDGLKPVQRRILYAM+ GNT DK +RKSAKTVG+ Sbjct: 12 LEEVLGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMHVEGNTADKHFRKSAKTVGN 71 Query: 65 VMGNYHPHGDSSIYEGMVRMAQPWKMGHVLIDGHGNWGSMDDDPAAAMRYTEARLSPIAM 124 V+GNYHPHGDSS+YE MVRM+Q WK+ +VLI+ HGN GS+D DPAAAMRYTEARL+PIA Sbjct: 72 VIGNYHPHGDSSVYEAMVRMSQDWKLRNVLIEMHGNNGSIDGDPAAAMRYTEARLAPIAS 131 Query: 125 EMMRDIEKRTVLFKDNFDNTAKEPVVVPSRYPNLLVNGTSGISAGFATEIPPHNLREVID 184 E++ DI+K TV F NFD+TA EPVV+P+R+PNLLVNG++GISAG+ATEIPPH+L E+ID Sbjct: 132 ELLHDIDKETVKFIPNFDDTANEPVVLPARFPNLLVNGSTGISAGYATEIPPHHLGEIID 191 Query: 185 ACIAVMQKPDIALEDIMTFIKGPDFPXXXXXXXXXXXXDAYRTGKGRIYLRSKTEIENLR 244 I M+ PD +ED+MT IKGPDFP AY TGKG++ +R +T IE +R Sbjct: 192 GAIMRMENPDCTVEDLMTVIKGPDFPTGGIVQGIDGIKKAYETGKGKMVVRGRTSIEEIR 251 Query: 245 GGKQQIVITEVPFQIVKSRLVTSMENIRLEKKIEGIAEVRDESGRDGLRIVVELKKEADA 304 GG++QIVI E+P+++ K+ LV ++ +R+++K+EGI+EVRDE+ R GLRIV+ELKK+ADA Sbjct: 252 GGRKQIVIAEIPYEVNKANLVKKIDELRIDRKVEGISEVRDETDRTGLRIVIELKKDADA 311 Query: 305 QGILAYLLKKTDLQVTYNFNMVAIVNKSPQQLGLKAILEAYIAHQREVVTHRTQFDLEKA 364 +L YL K TDLQV+YNFNMVAI N+ PQ +GL+ +L+AYI HQ+EVVT RT+FDL+KA Sbjct: 312 DSVLNYLFKNTDLQVSYNFNMVAIHNRRPQLMGLRELLDAYIEHQKEVVTKRTEFDLKKA 371 Query: 365 EDRAHVLEGLVKALNILDEVIAAIKASKNRQDAQNNLVWMFGFSERQADSILTLQLYRLT 424 DR H+++GL+KAL+ILDEVIAAI+ASK+++DA+ NL+ F F+E QA++I+TLQLYRLT Sbjct: 372 RDRKHIVDGLMKALSILDEVIAAIRASKDKKDAKANLIAKFAFTEPQAEAIVTLQLYRLT 431 Query: 425 NLEIHSLQKELDEMNARIAVLKGILESDKKLIAVIRKELIEIRDKYGIDRRSLIQGXXXX 484 N +I +L+ E ++ +I IL S+KKL VI+KEL +IR KY +RR+ I+ Sbjct: 432 NTDITTLENEAADLEKKIETYLAILSSEKKLFTVIKKELRDIRKKYADNRRTTIEAEIQE 491 Query: 485 XXXXXXXXXNAEDVLVALSADGYIKRTGMLSFTRSGGERNASGVKEGDHIVRLMDLNTRD 544 EDV+V ++ DGYIKRT + S+T S G A +K+ D ++ LNT Sbjct: 492 LKINLEAMIPNEDVMVTITKDGYIKRTSLRSYTASNGRDLA--IKDSDRLLFKQQLNTVQ 549 Query: 545 SLLVFTRKGQYFLLPVHQIPEFKWKEPGTAIVNVIGLAKGDGIASILPVGNMDDPGASLV 604 ++L+FT KG Y LPVH++P+ +WK+ G + N++ L + +GI +LP+ + + P ++ Sbjct: 550 TVLLFTNKGSYIYLPVHELPDIRWKDLGQHVSNLVTLERDEGIIKVLPIEDFNQP-QFIL 608 Query: 605 FVTRKGQVKRTELKEYSTSR-SGAVAACKVAEGDEVLTVALSSGDKEIVLVTREGMSIRF 663 F T+ G K+TEL++Y R S A+ A + DEVL V L+ G KE+ L +R G +RF Sbjct: 609 FFTKNGMAKKTELQQYQAQRYSKALVAINLKGDDEVLDVHLTDGSKEVFLASRLGYGLRF 668 Query: 664 RENEVNPMGRVASGVRGIQLREGDEVVSCFWVNEDEGE-ILAVTEIGYAKRTLLLDYPAQ 722 E E++ +G+ A+GV+G+ L+EGD +VS + + E + + T+ G K+ + ++ Sbjct: 669 DEAEISVVGQRAAGVKGMNLKEGDRLVSGKIIEDPEKDKVFIATQRGAVKKMKVSEFDKT 728 Query: 723 SRGGKGMPTFEFKEGKRVRPNGSRISGAFYCREPLELVAITREG 766 SR +G+ + ++ + RI+GA + + IT +G Sbjct: 729 SRAKRGVIML-----RELKAHPHRIAGAVIAGDDETVSVITEKG 767 >B7HAW9.1 B7HAW9_BACC4 DNA topoisomerase IV, A subunit EC=5.99.1.- Length = 807 Score = 778 bits (2009), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/798 (48%), Positives = 553/798 (69%), Gaps = 8/798 (1%) Query: 5 LEEVVGDRFGRYSKYIIQDRAIPDVRDGLKPVQRRILYAMYDSGNTPDKPYRKSAKTVGD 64 LE+V+GDRF RYSKYIIQDRA+PD RDGLKPVQRRILY+MY GN DK +RKSAKTVG+ Sbjct: 11 LEDVLGDRFARYSKYIIQDRALPDARDGLKPVQRRILYSMYVEGNVHDKAFRKSAKTVGN 70 Query: 65 VMGNYHPHGDSSIYEGMVRMAQPWKMGHVLIDGHGNWGSMDDDPAAAMRYTEARLSPIAM 124 V+GNYHPHGDSS+YE MVR++Q WK+ +VL++ HGN GS+D DPAAAMRYTEARLSPIA Sbjct: 71 VIGNYHPHGDSSVYEAMVRLSQTWKVRNVLVEMHGNNGSVDGDPAAAMRYTEARLSPIAS 130 Query: 125 EMMRDIEKRTVLFKDNFDNTAKEPVVVPSRYPNLLVNGTSGISAGFATEIPPHNLREVID 184 E++RD++K TV F NFD+T++EPVV+P+ +PNLLVNG++GISAG+ATEIPPH+L EVID Sbjct: 131 ELLRDLDKETVEFVSNFDDTSEEPVVLPAAFPNLLVNGSTGISAGYATEIPPHHLGEVID 190 Query: 185 ACIAVMQKPDIALEDIMTFIKGPDFPXXXXXXXXXXXXDAYRTGKGRIYLRSKTEIENLR 244 A + + KP+ ++D++T +KGPDFP AY TGKG+I +R K E+E +R Sbjct: 191 ATMMRIDKPNSTVDDLLTVMKGPDFPTGGIIQGIDGIKKAYETGKGKIIIRGKAEVETVR 250 Query: 245 GGKQQIVITEVPFQIVKSRLVTSMENIRLEKKIEGIAEVRDESGRDGLRIVVELKKEADA 304 GGKQQIVITE+P+++ K+ LV M+ +RL+KK++GIAEVRDE+ R GLRIVVELKKEA++ Sbjct: 251 GGKQQIVITEIPYEVNKANLVKKMDELRLDKKLDGIAEVRDETDRTGLRIVVELKKEANS 310 Query: 305 QGILAYLLKKTDLQVTYNFNMVAIVNKSPQQLGLKAILEAYIAHQREVVTHRTQFDLEKA 364 +GIL YL K TDLQ+ YNFNMVAI N+ P + L IL+AYI HQ+EV+T R+Q++L KA Sbjct: 311 EGILNYLYKNTDLQIPYNFNMVAINNRRPTLMTLPKILDAYIGHQKEVITRRSQYELRKA 370 Query: 365 EDRAHVLEGLVKALNILDEVIAAIKASKNRQDAQNNLVWMFGFSERQADSILTLQLYRLT 424 E+R H++EGL KAL+ILD+VI I+ASK++++A++NL FGF+E QA++I++LQLYRLT Sbjct: 371 ENRQHIVEGLKKALSILDQVIETIRASKDKRNAKDNLSAKFGFTEAQAEAIVSLQLYRLT 430 Query: 425 NLEIHSLQKELDEMNARIAVLKGILESDKKLIAVIRKELIEIRDKYGIDRRSLIQGXXXX 484 N +I +LQ+E DE+N +I L+ IL+S+KKL+ VI+ +L ++ Y DRR++I+ Sbjct: 431 NTDITALQEEADELNKKIIELQAILQSEKKLLQVIKTDLKRVKKTYSDDRRAIIEDQIEE 490 Query: 485 XXXXXXXXXNAEDVLVALSADGYIKRTGMLSFTRSGGERNASGVKEGDHIVRLMDLNTRD 544 EDV+V ++ +GY+KRTG S S G+ G+KEGD ++ D NT + Sbjct: 491 IKIDVEVMIPQEDVIVTVTKEGYVKRTGWRSHNASNGK--DFGMKEGDILLERFDTNTTE 548 Query: 545 SLLVFTRKGQYFLLPVHQIPEFKWKEPGTAIVNVIGLAKGDGIASILPVGNMDDPGASLV 604 ++L+FT KG Y LPV+++P+ +WK+ G + N++ L + + I V N ++ +V Sbjct: 549 TVLLFTNKGNYIYLPVYEMPDIRWKDLGQHVANIVSLDRDETIIWATVVPNFEEEKRFIV 608 Query: 605 FVTRKGQVKRTELKEYSTSR-SGAVAACKVAEGDEVLTVALSSGDKEIVLVTREGMSIRF 663 FVTR G +K+TEL +Y R S A A + + DEV+ + + G +IVL T ++ F Sbjct: 609 FVTRNGMIKKTELNQYKVQRYSRAFVAVNLKKDDEVVDIFATDGTSDIVLATHGAYALIF 668 Query: 664 RENEVNPMGRVASGVRGIQLREGDEVVSCFWVNEDEGEILAVTEIGYAKRTLLLDYPAQS 723 E+EV+P+G A+GV+ I L+E D V S +N D+ +++ VT+ G KR + + Sbjct: 669 HEDEVSPVGVRAAGVKAINLKEDDYVASGKPLNGDKDQLILVTQRGAVKRLKASEIEKST 728 Query: 724 RGGKGMPTFEFKEGKRVRPNGSRISGAFYCREPLELVAITREGATHSFSSESAPLSERRS 783 R +G+ FKE KR N RI G R+ + T + ++ +R S Sbjct: 729 RAKRGLVI--FKELKR---NPYRIVGIEIVRDDELVYMKTEKNIVEEIDPKAYRNKDRYS 783 Query: 784 IGKQLVSVEKKDEIISLF 801 G ++ V E++ + Sbjct: 784 NGSLVLDVNDTGEVVETW 801 >C3H448.1 C3H448_BACTU DNA topoisomerase 4 subunit A Length = 807 Score = 778 bits (2008), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/798 (48%), Positives = 553/798 (69%), Gaps = 8/798 (1%) Query: 5 LEEVVGDRFGRYSKYIIQDRAIPDVRDGLKPVQRRILYAMYDSGNTPDKPYRKSAKTVGD 64 LE+V+GDRF RYSKYIIQDRA+PD RDGLKPVQRRILY+MY GN DK +RKSAKTVG+ Sbjct: 11 LEDVLGDRFARYSKYIIQDRALPDARDGLKPVQRRILYSMYVEGNVHDKAFRKSAKTVGN 70 Query: 65 VMGNYHPHGDSSIYEGMVRMAQPWKMGHVLIDGHGNWGSMDDDPAAAMRYTEARLSPIAM 124 V+GNYHPHGDSS+YE MVR++Q WK+ +VL++ HGN GS+D DPAAAMRYTEARLSPIA Sbjct: 71 VIGNYHPHGDSSVYEAMVRLSQTWKVRNVLVEMHGNNGSVDGDPAAAMRYTEARLSPIAS 130 Query: 125 EMMRDIEKRTVLFKDNFDNTAKEPVVVPSRYPNLLVNGTSGISAGFATEIPPHNLREVID 184 E++RD++K TV F NFD+T++EPVV+P+ +PNLLVNG++GISAG+ATEIPPH+L EVID Sbjct: 131 ELLRDLDKETVEFVSNFDDTSEEPVVLPAAFPNLLVNGSTGISAGYATEIPPHHLGEVID 190 Query: 185 ACIAVMQKPDIALEDIMTFIKGPDFPXXXXXXXXXXXXDAYRTGKGRIYLRSKTEIENLR 244 A + + KP+ ++D++T +KGPDFP AY TGKG+I +R K E+E +R Sbjct: 191 ATMMRIDKPNSTVDDLLTVMKGPDFPTGGIIQGIDGIKKAYETGKGKIIIRGKAEVETVR 250 Query: 245 GGKQQIVITEVPFQIVKSRLVTSMENIRLEKKIEGIAEVRDESGRDGLRIVVELKKEADA 304 GGKQQIVITE+P+++ K+ LV M+ +RL+KK++GIAEVRDE+ R GLRIVVELKKEA+A Sbjct: 251 GGKQQIVITEIPYEVNKANLVKKMDELRLDKKLDGIAEVRDETDRTGLRIVVELKKEANA 310 Query: 305 QGILAYLLKKTDLQVTYNFNMVAIVNKSPQQLGLKAILEAYIAHQREVVTHRTQFDLEKA 364 +GIL YL K TDLQ+ YNFNMVAI N+ P + L IL+AYI HQ+EV+T R+Q++L KA Sbjct: 311 EGILNYLYKNTDLQIPYNFNMVAINNRRPTLMTLPKILDAYIGHQKEVITRRSQYELRKA 370 Query: 365 EDRAHVLEGLVKALNILDEVIAAIKASKNRQDAQNNLVWMFGFSERQADSILTLQLYRLT 424 E+R H++EGL KAL+ILD+VI I+ASK++++A++NL FGF+E QA++I++LQLYRLT Sbjct: 371 ENRQHIVEGLKKALSILDQVIETIRASKDKRNAKDNLSAKFGFTEAQAEAIVSLQLYRLT 430 Query: 425 NLEIHSLQKELDEMNARIAVLKGILESDKKLIAVIRKELIEIRDKYGIDRRSLIQGXXXX 484 N +I +LQ+E DE+N +I L+ IL+S+K+L+ VI+ +L ++ Y DRR++I+ Sbjct: 431 NTDITALQEEADELNKKIIELQAILQSEKRLLQVIKTDLKRVKKTYSDDRRAIIEDQIEE 490 Query: 485 XXXXXXXXXNAEDVLVALSADGYIKRTGMLSFTRSGGERNASGVKEGDHIVRLMDLNTRD 544 EDV+V ++ +GY+KRTG S S G+ G+KEGD ++ D NT + Sbjct: 491 IKIDVEVMIPQEDVIVTVTKEGYVKRTGWRSHNASNGK--DFGMKEGDILLERFDTNTTE 548 Query: 545 SLLVFTRKGQYFLLPVHQIPEFKWKEPGTAIVNVIGLAKGDGIASILPVGNMDDPGASLV 604 ++L+FT KG Y LPV+++P+ +WK+ G + N++ L + + I V N ++ +V Sbjct: 549 TVLLFTNKGNYIYLPVYEMPDIRWKDLGQHVANIVSLDRDETIIWATVVPNFEEEKRFIV 608 Query: 605 FVTRKGQVKRTELKEYSTSR-SGAVAACKVAEGDEVLTVALSSGDKEIVLVTREGMSIRF 663 FVTR G +K+TEL +Y R S A A + + DEV+ + + G +IVL T ++ F Sbjct: 609 FVTRNGMIKKTELNQYKVQRYSRAFVAVNLKKDDEVVDIFATDGTSDIVLATHGAYALIF 668 Query: 664 RENEVNPMGRVASGVRGIQLREGDEVVSCFWVNEDEGEILAVTEIGYAKRTLLLDYPAQS 723 E+EV+P+G A+GV+ I L+E D V S +N D+ +++ VT+ G KR + + Sbjct: 669 HEDEVSPVGVRAAGVKAINLKEDDYVASGKPLNGDKDQLILVTQRGAVKRLKASEIEKST 728 Query: 724 RGGKGMPTFEFKEGKRVRPNGSRISGAFYCREPLELVAITREGATHSFSSESAPLSERRS 783 R +G+ FKE KR N RI G R+ + T + ++ +R S Sbjct: 729 RAKRGLVI--FKELKR---NPYRIVGIEIVRDDELVYMKTEKNIVEEIDPKAYRNKDRYS 783 Query: 784 IGKQLVSVEKKDEIISLF 801 G ++ V E++ + Sbjct: 784 NGSLVLDVNDTGEVVETW 801 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.136 0.385 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 4,500,937,671 Number of extensions: 189186421 Number of successful extensions: 498947 Number of sequences better than 1.0e-05: 4528 Number of HSP's gapped: 479251 Number of HSP's successfully gapped: 5142 Length of query: 805 Length of database: 3,060,696,203 Length adjustment: 144 Effective length of query: 661 Effective length of database: 1,704,070,043 Effective search space: 1126390298423 Effective search space used: 1126390298423 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 136 (57.0 bits)