BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0348.0014.p (219 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q889B9.1 Q889B9_PSESM RibD C-terminal domain protein 203 1e-50 Q48FD7.1 Q48FD7_PSE14 RibD C-terminal domain protein 203 1e-50 C0QTD6.1 C0QTD6_PERMH Diaminohydroxyphosphoribosylaminopyrimidin... 146 1e-33 B2V7E8.1 B2V7E8_SULSY 2, 5-diamino-6-hydroxy-4-(5-phosphoribosyl... 144 5e-33 C4FJ40.1 C4FJ40_9AQUI Diaminohydroxyphosphoribosylaminopyrimidin... 139 2e-31 >Q889B9.1 Q889B9_PSESM RibD C-terminal domain protein Length = 224 Score = 203 bits (516), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 97/217 (44%), Positives = 135/217 (62%), Gaps = 1/217 (0%) Query: 1 MKTTIFSQVSIDGKLTLGAGKSSKQLFSMFEEPDIKYIHQFRGLIDAIMVGKNTIQYDDP 60 MK T+FSQ+SIDGKLT+G G SSK LF F++ D+++IH+FRG +DAIMVG+NTI DDP Sbjct: 1 MKVTVFSQISIDGKLTMGKGASSKPLFQNFDDDDMRFIHKFRGEVDAIMVGRNTIVTDDP 60 Query: 61 MLTNRYEENKNPLRIIPTTHMDISLDSHVLADDGRTLIVTTENGKNPEMINILKDRNKDV 120 LTNRYE +NP+RIIPTT +D+ + + +T+I T+E ++ EM+ ++ K+V Sbjct: 61 QLTNRYESGRNPIRIIPTTSLDLPTSASIFKSPEKTIIATSEQARDHEMVKHIRACGKEV 120 Query: 121 LICGKDKVDFVNLFRELEENYNVHSIMIEGGGFLNWNVLDQDLVDEXXXXXXXXXXXXXT 180 L G VDF LF LE ++ IM+EGGG LNW V + DLVDE Sbjct: 121 LFAGAKHVDFTRLFPMLEAR-GINHIMVEGGGHLNWQVFNLDLVDEIILMQVPIIIGGAA 179 Query: 181 NITLVDGTGYTDLNFVKKFKVVEVLPNKNYTLLRYQK 217 TL DG GY D+N F + + +Y L+ +++ Sbjct: 180 TATLADGVGYRDINMANSFTLHALEARPHYNLMHFKR 216 >Q48FD7.1 Q48FD7_PSE14 RibD C-terminal domain protein Length = 217 Score = 203 bits (516), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 98/217 (45%), Positives = 135/217 (62%), Gaps = 1/217 (0%) Query: 1 MKTTIFSQVSIDGKLTLGAGKSSKQLFSMFEEPDIKYIHQFRGLIDAIMVGKNTIQYDDP 60 MK T+FSQ+SIDGKLT+G G SSK LF F++ D+++IH+FRG +DAIMVG+NTI DDP Sbjct: 1 MKVTVFSQISIDGKLTMGKGASSKPLFQNFDDDDMRFIHKFRGEVDAIMVGRNTIVTDDP 60 Query: 61 MLTNRYEENKNPLRIIPTTHMDISLDSHVLADDGRTLIVTTENGKNPEMINILKDRNKDV 120 LTNRYE +NP+RIIPTT +D+ + + +T+I TTE ++ EM+ ++ K+V Sbjct: 61 QLTNRYESGRNPIRIIPTTSLDLPTSASIFKSPEKTIIATTEQARDHEMVKHIRACGKEV 120 Query: 121 LICGKDKVDFVNLFRELEENYNVHSIMIEGGGFLNWNVLDQDLVDEXXXXXXXXXXXXXT 180 L G VDF LF LE ++ IM+EGGG LNW V + DLVDE Sbjct: 121 LFAGAKHVDFTRLFPMLEVR-GINHIMVEGGGHLNWQVFNLDLVDEIILMQVPIIIGGAA 179 Query: 181 NITLVDGTGYTDLNFVKKFKVVEVLPNKNYTLLRYQK 217 TL DG GY D+N F + + +Y L+ +++ Sbjct: 180 TATLADGVGYRDINMANSFTLHALEARPHYNLMHFKR 216 >C0QTD6.1 C0QTD6_PERMH Diaminohydroxyphosphoribosylaminopyrimidine reductase EC=1.1.1.- Length = 221 Score = 146 bits (369), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 81/199 (40%), Positives = 119/199 (59%), Gaps = 3/199 (1%) Query: 3 TTIFSQVSIDGKLTLGAGKSSKQLFSMFEEPDIKYIHQFRGLIDAIMVGKNTIQYDDPML 62 T I S+V++DGKLTL G+SSK++ ++ +Y+H+ R +D IMVG TI+ D+P L Sbjct: 6 TIIVSEVTVDGKLTLRRGRSSKEIMQFMDDEANRYLHELRAKVDGIMVGAETIRTDNPFL 65 Query: 63 TNRYEENKNPLRIIPTTHMDISLDSHVLADDGRTLIVTTENGKNPEMINILKDRNKDVLI 122 T RY E KNP RI+PT+ DI LD+++L T+IVT+E+ E + LK++ +V+I Sbjct: 66 TVRYVEGKNPTRIVPTSKADIPLDANILEKHAPTIIVTSESAPE-EKVKALKEK-VEVII 123 Query: 123 CGKDKVDFVNLFRELEENYNVHSIMIEGGGFLNWNVLDQDLVDEXXXXXXXXXXXXXTNI 182 GKD+VD + + L + ++M+EGG LNWN++ LVDE Sbjct: 124 SGKDQVDLIEMMDTLYRK-GIKTLMVEGGSTLNWNLIKFGLVDEIRLIHMPFIVGGEDTP 182 Query: 183 TLVDGTGYTDLNFVKKFKV 201 TLV G G+ LN V K K+ Sbjct: 183 TLVGGEGFYSLNDVVKTKL 201 >B2V7E8.1 B2V7E8_SULSY 2, 5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase EC=1.1.1.193 Length = 221 Score = 144 bits (363), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 79/197 (40%), Positives = 116/197 (58%), Gaps = 3/197 (1%) Query: 5 IFSQVSIDGKLTLGAGKSSKQLFSMFEEPDIKYIHQFRGLIDAIMVGKNTIQYDDPMLTN 64 I S+V++DGKLTL G SSK++ +E +Y+H+ R +D IMVG TI+ D+P LT Sbjct: 8 IVSEVTVDGKLTLSKGVSSKEIMKFMDEEANRYLHETRAKVDGIMVGAETIRTDNPYLTV 67 Query: 65 RYEENKNPLRIIPTTHMDISLDSHVLADDGRTLIVTTENGKNPEMINILKDRNKDVLICG 124 RY KNP RIIPT+ DI LD+++L D T+IVTTE E + L ++ +V++ G Sbjct: 68 RYVSGKNPTRIIPTSTADIPLDANILKKDSPTIIVTTEKAPE-ERVKALSEK-VEVIVAG 125 Query: 125 KDKVDFVNLFRELEENYNVHSIMIEGGGFLNWNVLDQDLVDEXXXXXXXXXXXXXTNITL 184 K++VD + + ++ N + ++M+EGG LNWN++ LVDE TL Sbjct: 126 KEEVDLIKMM-DILYNKGIRNLMVEGGSTLNWNLIKNGLVDEIRIIHMPFIVGGTDTPTL 184 Query: 185 VDGTGYTDLNFVKKFKV 201 V G G+ L V K K+ Sbjct: 185 VGGEGFKSLEEVVKLKL 201 >C4FJ40.1 C4FJ40_9AQUI Diaminohydroxyphosphoribosylaminopyrimidine reductase EC=1.1.1.- Length = 221 Score = 139 bits (350), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 78/197 (39%), Positives = 115/197 (58%), Gaps = 3/197 (1%) Query: 5 IFSQVSIDGKLTLGAGKSSKQLFSMFEEPDIKYIHQFRGLIDAIMVGKNTIQYDDPMLTN 64 I S+V++DGKLTL G SSK++ +E +Y+H+ R +D IMVG TI+ D+P LT Sbjct: 8 IVSEVTVDGKLTLSKGVSSKEIMKFMDEEANRYLHETRAKVDGIMVGAETIRTDNPYLTV 67 Query: 65 RYEENKNPLRIIPTTHMDISLDSHVLADDGRTLIVTTENGKNPEMINILKDRNKDVLICG 124 RY KNP RIIPT+ I D+++L D T+IVTTE E + +L ++ +V+I G Sbjct: 68 RYVSGKNPTRIIPTSTAYIPPDANILKKDSPTIIVTTEKAPK-ERLKMLSEK-VEVIIAG 125 Query: 125 KDKVDFVNLFRELEENYNVHSIMIEGGGFLNWNVLDQDLVDEXXXXXXXXXXXXXTNITL 184 K++VD + + ++ N + ++M+EGG LNWN++ LVDE TL Sbjct: 126 KEEVDLIKMM-DILYNRGIRNLMVEGGSTLNWNLIKNGLVDEIRIIHMPFIVGGTDTPTL 184 Query: 185 VDGTGYTDLNFVKKFKV 201 V G G+ L V K K+ Sbjct: 185 VGGEGFKSLEEVVKLKL 201 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.138 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,278,732,915 Number of extensions: 53339645 Number of successful extensions: 118400 Number of sequences better than 1.0e-05: 501 Number of HSP's gapped: 118226 Number of HSP's successfully gapped: 501 Length of query: 219 Length of database: 3,060,696,203 Length adjustment: 130 Effective length of query: 89 Effective length of database: 1,835,964,253 Effective search space: 163400818517 Effective search space used: 163400818517 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 128 (53.9 bits)