BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0348.0005.p (207 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C0ZJV9.1 C0ZJV9_BREBN Probable transcriptional regulator 244 3e-63 Q9KBG3.1 Q9KBG3_BACHD Transcriptional regulator (TetR/AcrR family) 224 5e-57 B1DD37.1 B1DD37_9BACL Transcriptional regulator, TetR family 165 3e-39 C2W331.1 C2W331_BACCE Transcription regulator, TetR/AcrR 134 7e-30 A7GKA3.1 A7GKA3_BACCN Transcriptional regulator, TetR family 132 3e-29 >C0ZJV9.1 C0ZJV9_BREBN Probable transcriptional regulator Length = 200 Score = 244 bits (624), Expect = 3e-63, Method: Compositional matrix adjust. Identities = 110/185 (59%), Positives = 144/185 (77%) Query: 10 EKLLSAAIDLISEKGYNGVTTQEIAAAAGLSEKTLFRHFGSKQNLLESALERFQYAEEMR 69 EKL+ AAIDLI+E+GYNGVTTQEIA AGLSEKTLFRHFGSK+NLLESA +RF Y E + Sbjct: 15 EKLMIAAIDLIAERGYNGVTTQEIATMAGLSEKTLFRHFGSKRNLLESAFDRFHYTEGLT 74 Query: 70 VFFSGKLVWELESDLLSISKKYHEIMNRDRKLIQIAIQDEGHIPGFKERRLQHPRQLLVF 129 F+ KL W L DLL IS+ YHE+MNR+RK+I I+I+DE H+PGF+ER +HP+QL+V Sbjct: 75 KLFAEKLTWNLREDLLLISRTYHEMMNRNRKMILISIKDEAHLPGFRERTQKHPQQLMVL 134 Query: 130 LADYFNKMNEKGKAACSNPTMQAFTFMMAQYGAFINDLEAGNNYPGISLDQFIQENVKIF 189 DYF +M +KGK +NP QA FM+ +GAF+NDL+ +N+ G+SLD FI+E+V++F Sbjct: 135 FTDYFKEMGKKGKMIQTNPEAQATAFMVMNFGAFLNDLDGTSNFSGVSLDAFIEESVEVF 194 Query: 190 VKSLS 194 + L+ Sbjct: 195 ARGLT 199 >Q9KBG3.1 Q9KBG3_BACHD Transcriptional regulator (TetR/AcrR family) Length = 196 Score = 224 bits (570), Expect = 5e-57, Method: Compositional matrix adjust. Identities = 107/189 (56%), Positives = 143/189 (75%), Gaps = 1/189 (0%) Query: 7 GSTEKLLSAAIDLISEKGYNGVTTQEIAAAAGLSEKTLFRHFGSKQNLLESALERFQYAE 66 G++EKL+ AAIDLISE+GYNGVTT EIAAAAG SEKTLFRHFGSKQNLLE A +RF Y E Sbjct: 7 GTSEKLMIAAIDLISERGYNGVTTLEIAAAAGFSEKTLFRHFGSKQNLLEQAFDRFHYGE 66 Query: 67 EMRVFFSGKLVWELESDLLSISKKYHEIMNRDRKLIQIAIQDEGHIPGFKERRLQHPRQL 126 EM+ F KLVW+L DLL IS+ YH IMNR+RK+IQIAI++ ++PGF+ER +HP+QL Sbjct: 67 EMKGLFKEKLVWDLHEDLLMISQTYHTIMNRNRKMIQIAIKEGKNLPGFRERTHRHPQQL 126 Query: 127 LVFLADYFNKMNEKGKAACSNPTMQAFTFMMAQYGAFINDLEAG-NNYPGISLDQFIQEN 185 FL YF++M +K K +P A +FM+ +GAFIN+L++ + +SL++FI + Sbjct: 127 KEFLTTYFSEMIKKRKMIDVHPEHTAVSFMLLNFGAFINELDSDKKRFTNVSLEEFITNS 186 Query: 186 VKIFVKSLS 194 V++F + L+ Sbjct: 187 VRVFTRGLT 195 >B1DD37.1 B1DD37_9BACL Transcriptional regulator, TetR family Length = 192 Score = 165 bits (417), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 80/184 (43%), Positives = 120/184 (65%), Gaps = 1/184 (0%) Query: 11 KLLSAAIDLISEKGYNGVTTQEIAAAAGLSEKTLFRHFGSKQNLLESALERFQYAEEMRV 70 KL+ AAIDL++EKGY GV+T+EIA AG+SE TLFR+F +K NLL+ A+E F Y+ EM Sbjct: 9 KLMQAAIDLMAEKGYKGVSTKEIATVAGVSEMTLFRNFANKLNLLDKAVEHFHYSIEMNR 68 Query: 71 FFSGKLVWELESDLLSISKKYHEIMNRDRKLIQIAIQDEGHIPGFKERRLQHPRQLLVFL 130 F ++VW++ +DLL +S+ YHE+M R+RKL I + D + +++ +HPR LL L Sbjct: 69 IFQEEVVWDIRADLLLVSEMYHELMERNRKLFLIVLAD-NDLADIRQKAQKHPRILLELL 127 Query: 131 ADYFNKMNEKGKAACSNPTMQAFTFMMAQYGAFINDLEAGNNYPGISLDQFIQENVKIFV 190 +YF +M + K ++ QA TFM YGAFI+ L ++ + F + +V +FV Sbjct: 128 MNYFTEMQRQHKMIDTDAETQAITFMWMNYGAFISRLYTAEAVTKVTREMFAESSVDLFV 187 Query: 191 KSLS 194 ++LS Sbjct: 188 RALS 191 >C2W331.1 C2W331_BACCE Transcription regulator, TetR/AcrR Length = 193 Score = 134 bits (336), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 64/189 (33%), Positives = 113/189 (59%) Query: 5 KQGSTEKLLSAAIDLISEKGYNGVTTQEIAAAAGLSEKTLFRHFGSKQNLLESALERFQY 64 + + +K++ AAI+L+ EKGY TT+EIA AG++E T+FR+F +K+ ++E+A+ F Y Sbjct: 3 RSKTADKIIQAAIELVKEKGYKAATTKEIAIRAGVNEVTIFRNFKNKKGVIEAAVYEFSY 62 Query: 65 AEEMRVFFSGKLVWELESDLLSISKKYHEIMNRDRKLIQIAIQDEGHIPGFKERRLQHPR 124 ++ F ++VWELE+DL ++++ YH+ +N + +I I I++ G P E + P+ Sbjct: 63 VPHLQRFLQTEIVWELETDLKNLARHYHKFLNEAKDIISIGIRETGLFPELDEEIAKIPK 122 Query: 125 QLLVFLADYFNKMNEKGKAACSNPTMQAFTFMMAQYGAFINDLEAGNNYPGISLDQFIQE 184 L L YF +M KGK +N Q F+ +G F++ L N I+ + FI+ Sbjct: 123 GLKEELMSYFAQMQRKGKIIDTNIEAQVMNFIWINFGYFLSKLRFENRLMEINDEDFIEN 182 Query: 185 NVKIFVKSL 193 N+ ++ ++L Sbjct: 183 NITLYTRAL 191 >A7GKA3.1 A7GKA3_BACCN Transcriptional regulator, TetR family Length = 193 Score = 132 bits (331), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 61/189 (32%), Positives = 114/189 (60%) Query: 5 KQGSTEKLLSAAIDLISEKGYNGVTTQEIAAAAGLSEKTLFRHFGSKQNLLESALERFQY 64 + + EK++ AAI+L+ E+GY TT+EIA AG++E T+FR+F +K+ ++E+A+ F Y Sbjct: 3 RSKTAEKIIQAAIELVKERGYKAATTREIAMRAGVNEVTIFRNFKNKKGVIEAAVAEFSY 62 Query: 65 AEEMRVFFSGKLVWELESDLLSISKKYHEIMNRDRKLIQIAIQDEGHIPGFKERRLQHPR 124 ++ F ++VWELE+DL ++++ YH+ +N + +I I I++ G P + + P+ Sbjct: 63 VPHLKHFLQTRIVWELETDLKNLARHYHQFLNEVKDIIAIGIRETGAFPELDDEIAKIPK 122 Query: 125 QLLVFLADYFNKMNEKGKAACSNPTMQAFTFMMAQYGAFINDLEAGNNYPGISLDQFIQE 184 L L YF +M +KGK +N Q F+ +G F++ + N ++ + FI+ Sbjct: 123 GLKEELMIYFTEMQKKGKIIDTNIEAQVMNFIWINFGYFLSKMRFENRLMEMNDEDFIEN 182 Query: 185 NVKIFVKSL 193 N+ ++ ++L Sbjct: 183 NITLYARAL 191 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.134 0.376 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,144,307,632 Number of extensions: 42849981 Number of successful extensions: 131525 Number of sequences better than 1.0e-05: 144 Number of HSP's gapped: 131743 Number of HSP's successfully gapped: 144 Length of query: 207 Length of database: 3,060,696,203 Length adjustment: 129 Effective length of query: 78 Effective length of database: 1,845,385,268 Effective search space: 143940050904 Effective search space used: 143940050904 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 128 (53.9 bits)