BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0346.0043.p (609 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K644.1 B3K644_9BACI Histidine kinase internal region 394 e-107 B1D784.1 B1D784_9BACL Histidine kinase internal region 362 5e-98 A9U830.1 A9U830_PHYPA Predicted protein (Fragment) 223 3e-56 B0K338.1 B0K338_THEPX Histidine kinase internal region 171 2e-40 A7B0I5.1 A7B0I5_RUMGN Putative uncharacterized protein 170 4e-40 >B3K644.1 B3K644_9BACI Histidine kinase internal region Length = 598 Score = 394 bits (1012), Expect = e-107, Method: Compositional matrix adjust. Identities = 213/600 (35%), Positives = 337/600 (56%), Gaps = 12/600 (2%) Query: 12 MKLRTKLIVCFVLLISIPSVTNAVINYKTSSDIIVSNAEDSILEIVKKKTEISDLLLNHI 71 M+L+ KLI+ +++LI++P VT ++ S ++++ A D++ EIV+K +I D L I Sbjct: 1 MRLKNKLILSYIILITLPLVTLGTGSFYASKNMMLKLARDNVTEIVQKNNQIIDERLKII 60 Query: 72 EARTIDLISDPDLFNLFDRQQPQNDDELLKMDRKATEILNKYFRSGQDFYTVQLVTSYYS 131 + ++ L+ + DLF +FD P +LL +++ TEILN+YF +D Y+V+LVT + Sbjct: 61 QDNSLSLMVECDLFQIFDGAAPAQS-KLLATNKQVTEILNRYFSQSRDLYSVELVTRAFV 119 Query: 132 FGGGATGYTTNPTFVSVPPKGFTQSYIYQKITEAKGSLQWFPTYDWTRIFGQPELGGMDA 191 +G A + PP F S +Y++ +E KG L W PTYD++ + P+L G D Sbjct: 120 YGSKARN--------TYPPDHFYDSELYRQASEQKGRLAWVPTYDYSLMHQLPDLAGADI 171 Query: 192 RFRMVFSAGRVLNISPII-DGMSRSWPETVERPVLLINFNEEYYRQNMAQAPAVKGSYFY 250 +R +FSA R +N S + D + R+ + E+PVL++NF + Y + ++GS F Sbjct: 172 EYRYLFSAVRQMNPSCVRNDAIVRARAGS-EKPVLVMNFRDGLYADLFRNSIPIEGSVFL 230 Query: 251 VVSRAGQIVTHPDHSLLGMSDGNRWHQDQFKSAAGTSLVKAGKEDVLIGYAASGVTGWVT 310 V G I++H + +G W + +G S V + + Y S +TGW + Sbjct: 231 VAGADGTIISHANAEFVGRKPSFPWLAEVQNRGSGASFVMVDGKRTIACYTTSAITGWTS 290 Query: 311 VYVVPYRQLLRNL-PTVNYTDLFITXXXXXXXXXXXXXXXXHLTQPIKKMMAAIQLTGAG 369 V ++P L +++ T+ + L + +T P++K++ AI+ G G Sbjct: 291 VVLIPPGALTKDIGQTITFFILTLGASLLLLSLFFAYLISMRITSPVRKLLLAIKRVGGG 350 Query: 370 NFSTKIPEPSQLEFRILVKRYNQMNERILELIEENYKSTRREKEAEMLALNLQLNPHFLY 429 +F+ KI + E ++ ++N MNE++ +LIEENY + RE+E E+LAL +QLNPHFLY Sbjct: 351 DFNAKIKVEGKDELGHVLMKFNSMNEKVRQLIEENYVAKLRERETEILALGIQLNPHFLY 410 Query: 430 NTLNIINWMALAREETEISQMIVSLSTMLQYTVNNGREEVLLEEDLNWLKSYTHIMGKRY 489 NTLNIINWMA+ E+ ++S+M+VSLS ML YT +N ++ + L ED+ WL+ Y IM R+ Sbjct: 411 NTLNIINWMAVYGEKEQVSRMLVSLSRMLHYTTDNRKDSMPLSEDIGWLQDYIVIMSNRF 470 Query: 490 AGVVEIGYDLEHLPPGIVVPKLFLQPIVENAIIHSMETVERGGRIIISGRKAGERLHFSV 549 + +D+E VPKLFLQP+VENAIIH +E GG I I GR G+ + F V Sbjct: 471 EHRFRVDFDIEPELMKARVPKLFLQPLVENAIIHGFRDMESGGLITIYGRSLGDDIEFCV 530 Query: 550 ADNGGGMSKAHIDALFIRDEGGIGLRNVKKRLNLMYGELAELQIQSEPXXXXXXXXXIPY 609 DNG G + + IG+ NV KR+ L+YG+ + I+S P IP+ Sbjct: 531 EDNGCGFEPERLKEALAENASHIGIHNVDKRIKLLYGDRYGIGIESVPELGTRVKLVIPH 590 >B1D784.1 B1D784_9BACL Histidine kinase internal region Length = 591 Score = 362 bits (930), Expect = 5e-98, Method: Compositional matrix adjust. Identities = 202/591 (34%), Positives = 327/591 (55%), Gaps = 20/591 (3%) Query: 12 MKLRTKLIVCFVLLISIPSVTNAVINYKTSSDIIVSNAEDSILEIVKKKTEISDLLLNHI 71 M R +L++ ++ LI++P + + + Y +S ++ A++++ ++V K ++ D L + Sbjct: 1 MTFRLRLLLSYLTLIALPLLVLSTLFYNSSLKVVTEQAQNNVHDVVMKNNDVIDTKLGIV 60 Query: 72 EARTIDLISDPDLFNLFDRQQPQNDDELLKMDRKATEILNKYFRSGQDFYTVQLVTSYYS 131 + + L D DLF +F+ P ++EL+ DR+ T IL+KYF D Y QL TSYY+ Sbjct: 61 DQNSRSLFVDKDLFQIFNNLNPAKEEELVAADRQVTAILSKYFSQNSDVYAAQLWTSYYT 120 Query: 132 FGGGATGYTTNPTFVSVPPKGFTQSYIYQKITEAKGSLQWFPTYDWTRIFGQPELGGMDA 191 FG +P QS IY++ +A G + W+PTYD+ +++ Q L Sbjct: 121 FGSTMLMPLGDPV----------QSAIYKEAVKAGGKMVWYPTYDFIKMYDQHWLQDGTI 170 Query: 192 RFRMVFSAGRVLNISPIIDGMSRSWPETVERPVLLINFN----EEYYRQNMAQAPAVKGS 247 +R +FSA R+LN S + D VERPVL I+F +E + +++ PA GS Sbjct: 171 DYRYLFSATRLLNFSHMEDSTLVKLKPEVERPVLAISFKSTVMDELFEKSI---PA--GS 225 Query: 248 YFYVVSRAGQIVTHPDHSLLGMSDGNRWHQDQFKSAAGTSLVKAGKEDVLIGYAASGVTG 307 + V+ +V D S + W D + +G+ +K + ++ +A S VTG Sbjct: 226 SYMVLDPDNIVVASSDQSQVTKRFDEDWMNDFREQGSGSERIKLNGHNQIVSFARSEVTG 285 Query: 308 WVTVYVVPYRQLLRNL-PTVNYTDLFITXXXXXXXXXXXXXXXXHLTQPIKKMMAAIQLT 366 W+++ + P L+ +L P + + + +T PIKK+M+A++ Sbjct: 286 WMSIVITPQSVLVSSLVPVLRTSTIVSAIALSAVALLFAYFIISRITGPIKKLMSAMRSV 345 Query: 367 GAGNFSTKIPEPSQLEFRILVKRYNQMNERILELIEENYKSTRREKEAEMLALNLQLNPH 426 G G+F ++ + EF +L +R+N+MN+RI L++ENY+ +EKEAE+ ALN+Q+NPH Sbjct: 346 GEGDFEARVDVDRKDEFGLLSQRFNRMNDRIAMLVKENYEIKLKEKEAEIQALNMQMNPH 405 Query: 427 FLYNTLNIINWMALAREETEISQMIVSLSTMLQYTVNNGREEVLLEEDLNWLKSYTHIMG 486 FLYNTLNI+NW AL +TE+S+M+V LS ML YT E V L E+L W+++Y IM Sbjct: 406 FLYNTLNIMNWTALENRQTELSKMLVCLSNMLHYTSRKDWEAVHLSEELEWMRNYFFIMS 465 Query: 487 KRYAGVVEIGYDLEHLPPGIVVPKLFLQPIVENAIIHSMETVERGGRIIISGRKAGERLH 546 R+ G + Y++E + +P+L QP VENAI+H VE GG+I I G + + Sbjct: 466 ARFEGKFTVAYEIEPVLYENKLPRLLFQPFVENAILHGFSGVEEGGQITIRGWIEDDSRY 525 Query: 547 FSVADNGGGMSKAHIDALFIRDEGGIGLRNVKKRLNLMYGELAELQIQSEP 597 F V DNG G+SK IDA+ ++ IG++N R+ + YG+ ++I S P Sbjct: 526 FEVRDNGRGISKEGIDAILYKESASIGIKNTISRIRMAYGDEYGIRIHSAP 576 >A9U830.1 A9U830_PHYPA Predicted protein (Fragment) Length = 367 Score = 223 bits (569), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 134/375 (35%), Positives = 203/375 (54%), Gaps = 10/375 (2%) Query: 102 MDRKATEILNKYFRSGQDFYTVQLVTSYYSFGGGATGYTTNPTFVSVPPKGFTQSYIYQK 161 M++K + +N YF + Y++ L+TSY G TG TT +P +GF Q+ +YQ Sbjct: 1 MEKKVSRAMNTYFPDLKHMYSIHLITSYSDIG--PTGATT-----FIPYEGFNQTALYQA 53 Query: 162 ITEAKGSLQWFPTYDWTRIFGQPELGGMDARFRMVFSAGRVLNISPIIDGMSRSWPETVE 221 +A G + W PT+ + +F + + + + + R+L + I +G E Sbjct: 54 AVQADGGMAWVPTFSFGDMFHRDAGSPVPSENVQLLAGVRLLKLFRINNGEVIELQGAAE 113 Query: 222 RPVLLINFNEEYYRQNMAQAPAVKGSYFYVVSRAGQIVTHPDHSLLGMSDGNRWHQDQFK 281 PVL+I + +YYR A G+ F+++SR GQ V M D + + K Sbjct: 114 LPVLVITYQPDYYRSRFASVLPSTGASFFIMSRDGQRVADSQEKDSTMDDTSLKRMAEMK 173 Query: 282 SAAGTSLVKAGKEDVLIGYAASGVTGWVT-VYVVPYRQLLRNLPTVNYTDLFITXXXXXX 340 S GT + + +++ + S VTGW++ V + P LP V ++T Sbjct: 174 S--GTLTITRNGKPLIVCFDTSDVTGWISGVMISPEALGSAFLPEVKSYTFYLTLILLLL 231 Query: 341 XXXXXXXXXXHLTQPIKKMMAAIQLTGAGNFSTKIPEPSQLEFRILVKRYNQMNERILEL 400 +T+PI++++ AI+ TG G F T+IP S E +L+ +YNQMN +I L Sbjct: 232 SLLLAFFLANSITKPIQQLLRAIKKTGEGEFDTRIPVKSYNEMGLLIHKYNQMNVKINNL 291 Query: 401 IEENYKSTRREKEAEMLALNLQLNPHFLYNTLNIINWMALAREETEISQMIVSLSTMLQY 460 IEENYK REKE ++++LN+QLNPHFLYNTLNI+NW AL E+ E+S MIVSLS+MLQY Sbjct: 292 IEENYKVKLREKETQIMSLNIQLNPHFLYNTLNIMNWTALENEQNELSAMIVSLSSMLQY 351 Query: 461 TVNNGREEVLLEEDL 475 T + ++ LEEDL Sbjct: 352 TSASNQDIGDLEEDL 366 >B0K338.1 B0K338_THEPX Histidine kinase internal region Length = 567 Score = 171 bits (434), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 119/433 (27%), Positives = 204/433 (47%), Gaps = 46/433 (10%) Query: 159 YQKITEAKGSLQWFPTYDWTRIFGQPELGGMDARFRMVFSAGRVLNISPIIDGMSRSWPE 218 Y+K + G L W+ D FG+ M + R+VF + Sbjct: 142 YKKTIQLNGRLYWYINDD----FGKQ----MISVSRLVFDI------------------K 175 Query: 219 TVERPVLLINFNEEYYRQNMAQAPAV-------KGSYFYVVSRAGQIVTHPDHSLLGMSD 271 +P+ +I+ + +M++ +V K Y+V G+++ D S L Sbjct: 176 NFAKPIAVISVD-----MDMSKVASVVSDIHLGKTGKVYLVDDKGKLIYSEDKSFLY--- 227 Query: 272 GNRWHQDQFKSAAGTSLVKAGKEDVLIGYAASGVTGWVTVYVVPYRQLLRNLPTVNYTDL 331 R+ + S++G+ + +++ Y GW V +V +L + Sbjct: 228 --RYTTKLYNSSSGSDFITINGNKIMVIYNTLPQNGWKLVGMVSMAELNEKAEMIRNFIY 285 Query: 332 FITXXXXXXXXXXXXXXXXHLTQPIKKMMAAIQLTGAGNFSTKIPEPSQLEFRILVKRYN 391 ++QPI K+ ++ GNF+ + E E +L +N Sbjct: 286 LTALLSLVIAALISLYFSYSISQPIIKLATEMKKVEKGNFNISVEENWDGEIGVLYSSFN 345 Query: 392 QMNERILELIEENYKSTRREKEAEMLALNLQLNPHFLYNTLNIINWMALAREETEISQMI 451 M ERI ELI E Y S +EK+AE+ AL Q+NPHFLYNTL+ +NW+A+ EIS+++ Sbjct: 346 YMIERINELIHEVYLSKIKEKDAELKALQAQINPHFLYNTLDTVNWLAVKHNVPEISKIV 405 Query: 452 VSLSTMLQYTVNNGREEVLLEEDLNWLKSYTHIMGKRYAGVVEIGYDLEHLPPGIVVPKL 511 SL+++L+Y++N G + +E +L ++SY I R+ E+ ++++ KL Sbjct: 406 NSLASILRYSINKGNDVTTVENELKHVESYITIQKIRFKDKFEVSFNIDKRVLHYKTIKL 465 Query: 512 FLQPIVENAIIHSMETVERGGRIIISGRKAGERLHFSVADNGGGMSKAHIDALF---IRD 568 LQP+VENAIIH +ET E G+I+I+G GE++ F V +NG + ++ L D Sbjct: 466 ILQPLVENAIIHGIETYEGKGKILINGYLDGEKIVFEVINNGNPIDLDLVNKLLDSPADD 525 Query: 569 EGGIGLRNVKKRL 581 + G++NV +R+ Sbjct: 526 KDSYGIQNVNERI 538 >A7B0I5.1 A7B0I5_RUMGN Putative uncharacterized protein Length = 602 Score = 170 bits (431), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 99/345 (28%), Positives = 176/345 (51%), Gaps = 6/345 (1%) Query: 248 YFYVVSRAGQIVTHPDHSLLGMSDGNRWHQDQFKSAAGTSLVKAGKEDVLIGYAASGVTG 307 Y +++ G ++ HP L+ +D S + G++ L + S TG Sbjct: 224 YIFILDEKGSMIYHPQQQLIYGGLKEERIEDILASKGDFLETEEGEDSKLYTMSKSEKTG 283 Query: 308 WVTVYVVPYRQLLRNLPTVNYTDLFITXXXXXXXXXXXXXXXXHLTQPIKKMMAAIQLTG 367 W V +L++N L +T+P++++ ++ L Sbjct: 284 WTVVGASYVTELMKNNRQAQMLYLLAAAGILIGVILISSFISSEITKPLRRLRDSMSLVE 343 Query: 368 AGNFSTKIPE-PSQLEFRILVKRYNQMNERILELIEENYKSTRREKEAEMLALNLQLNPH 426 G+F E ++ E L K +N M ++I L+E+N ++++++EM AL Q+NPH Sbjct: 344 KGDFEQASVEITAENEIGSLSKSFNAMTQKIHALMEQNIYEQKQKRKSEMKALQAQINPH 403 Query: 427 FLYNTLNIINWMALAREETEISQMIVSLSTMLQYTVNNGREEVLLEEDLNWLKSYTHIMG 486 FLYNTL+ I WM+ A E ++ M +L+ +L+ +++N RE++ + E++++++SY I Sbjct: 404 FLYNTLDSIIWMSEAGENDQVVLMTSALAKLLRQSISNDREQITVAEEIDYVRSYLTIQK 463 Query: 487 KRYAGVVEIGYDLEHLPPGIVVPKLFLQPIVENAIIHSMETVERGGRIIISGRKAGERLH 546 RY +E D+E + + K LQP+VENAI H ++ E G + I G + G R+ Sbjct: 464 MRYKDKLEYTIDVEERILDVRIIKFVLQPLVENAIYHGLKYKETKGNLDIRGYRRGNRVC 523 Query: 547 FSVADNGGGMSKAHIDALFIRDE-----GGIGLRNVKKRLNLMYG 586 VAD+G GM ++ ++ + + E G+G+ NV+KRL L YG Sbjct: 524 LVVADDGAGMEESELEHILEKKEKKTKSNGVGVYNVQKRLQLYYG 568 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,460,458,487 Number of extensions: 147107532 Number of successful extensions: 384806 Number of sequences better than 1.0e-05: 2014 Number of HSP's gapped: 381516 Number of HSP's successfully gapped: 2014 Length of query: 609 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 467 Effective length of database: 1,722,912,073 Effective search space: 804599938091 Effective search space used: 804599938091 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)