BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0346.0030.p (573 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KJ90.1 B3KJ90_9BACI Histidine kinase internal region 716 0.0 B1D5F6.1 B1D5F6_9BACL Integral membrane sensor signal transducti... 712 0.0 B1DBE2.1 B1DBE2_9BACL Histidine kinase internal region 223 5e-56 B3KBX4.1 B3KBX4_9BACI Histidine kinase internal region 198 1e-48 B1DHJ7.1 B1DHJ7_9BACL Histidine kinase internal region 179 1e-42 >B3KJ90.1 B3KJ90_9BACI Histidine kinase internal region Length = 579 Score = 716 bits (1848), Expect = 0.0, Method: Compositional matrix adjust. Identities = 355/566 (62%), Positives = 442/566 (78%), Gaps = 3/566 (0%) Query: 4 RKAGSKPYPIRHYVRIMILVSFAVLVLDLAISLASISIVKQQSTRYLQDTAKLYIDRINH 63 + +KPYPIRHYV+IM+ +S LV+DL IS ASI IVKQQSTRYLQDTA LYI +INH Sbjct: 3 KALNNKPYPIRHYVKIMLFISIFALVVDLVISFASIFIVKQQSTRYLQDTANLYIRQINH 62 Query: 64 DFAYINHYMGWTLANDETLNMMNAYEPDSSEFLKSNSNLYKRFSELQKNYGQEYNFFFYL 123 DF+YINHYMGWTLANDE++ +M+ D +++KS+ ++KRF+ELQKNYGQEYNFFFYL Sbjct: 63 DFSYINHYMGWTLANDESVKIMDTPGTDYVDYIKSSERVHKRFNELQKNYGQEYNFFFYL 122 Query: 124 KNQSFFLNCAPISVSYTDYLELKKLIYSYIEDKDVYAEFYSRWTPILVNGKYYIINIVPY 183 K+Q FF N AP+S+SYT++ ELK+ I S + K+VY FYS W PILV +Y+INIVPY Sbjct: 123 KDQDFFQNYAPMSLSYTEFQELKEQIVSLTDSKNVYETFYSNWNPILVQDTHYVINIVPY 182 Query: 184 YNRYLIGLISADNLIRPLRQINLGANGYASLVDENGTRISSPLSGSGKLVQQEQGWPGLL 243 +NRYLI LISAD+L+RPL++++LG +G+ SLVD G ++SP +G E L Sbjct: 183 HNRYLICLISADDLVRPLQELDLGEDGFVSLVDAQGAALTSPGAGEAGAKPLEGAKASLF 242 Query: 244 ---RSRTTISSEFSNTTFSADMVIQFGAFEKIMIAQLLIMLLFFIVTSTLCAVMLFFNKR 300 + RTT++ FSN +F+ +VIQFG FE IMIAQLLIMLLF ++T TL VML+F K+ Sbjct: 243 SLSQPRTTVTEGFSNASFNVQLVIQFGVFETIMIAQLLIMLLFVLLTCTLSVVMLYFKKK 302 Query: 301 VLGPIQNFSENLAHMNEDGQPAGFKSSKIIELEQASDQFKDLMEQVKTFKIAIYEQELEK 360 VL PIQNFSEN+ ++ED + F SS+IIELEQ + QFK L+EQ+K FKI IYEQELEK Sbjct: 303 VLKPIQNFSENVRRIHEDSENLDFMSSEIIELEQVNSQFKHLIEQIKKFKIDIYEQELEK 362 Query: 361 QRIQLDYMKQQIKPHFFLNCLTSIYSMAQIQMYEEIENMAMSTSKYFRYTFQDGGNFVRL 420 QRIQLDYMK QI PHFFLNCLT+IYSMAQ+QM++EIE M++STSKYFRY FQ G N VRL Sbjct: 363 QRIQLDYMKLQINPHFFLNCLTNIYSMAQMQMFKEIEYMSLSTSKYFRYIFQSGDNLVRL 422 Query: 421 EDEIEHIRIYLEIQRSRYRDAFRHHIVQDETAKDVQIPPLVLQTFIENSVKYAISRDPEV 480 EDEIEH+RIYLEIQ+ RYRDAF +HI ++ + IPPLVLQTFIEN+VKYA+SRD + Sbjct: 423 EDEIEHVRIYLEIQKHRYRDAFSYHIGYEQELAGLTIPPLVLQTFIENAVKYAVSRDQVL 482 Query: 481 QISLTVTRRESEEEQVTVIQISDNGPGFAPEVLEKLVRGQPLDQSKGTHIGIMNTLKRLE 540 QI LTV+ R +++ VI+ISD GPGF +VL+KL G+PLDQS+G HIGIMNTL+RLE Sbjct: 483 QIRLTVSLRVEDDKPYAVIRISDTGPGFPEDVLDKLANGKPLDQSEGKHIGIMNTLQRLE 542 Query: 541 YLYYKKAAVHFSNIEGGGASVIITLP 566 LY+ +A V FSN EGGGASV +TLP Sbjct: 543 LLYHHRAQVEFSNPEGGGASVALTLP 568 >B1D5F6.1 B1D5F6_9BACL Integral membrane sensor signal transduction histidine kinase Length = 581 Score = 712 bits (1837), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/576 (59%), Positives = 450/576 (78%), Gaps = 5/576 (0%) Query: 2 IKRKAGSKPYPIRHYVRIMILVSFAVLVLDLAISLASISIVKQQSTRYLQDTAKLYIDRI 61 + + + +K YPI+HYV+I++++SF L+LD IS ASI+IVKQQS R L+DTA LYI+RI Sbjct: 1 MTKPSENKLYPIQHYVKIILVISFTALILDFIISFASITIVKQQSARDLRDTAYLYINRI 60 Query: 62 NHDFAYINHYMGWTLANDETLNMMNAYEPDSSEFLKSNSNLYKRFSELQKNYGQEYNFFF 121 N DF+YINH+MGWTLANDE + MM ++ + +EF+K+N LY+RF ELQ +Y + YNFF Sbjct: 61 NSDFSYINHFMGWTLANDENVKMMETHDTNETEFIKANDALYRRFVELQTSYDKSYNFFI 120 Query: 122 YLKNQSFFLNCAPISVSYTDYLELKKLIYSYIEDKDVYAEFYSRWTPILVNGKYYIINIV 181 + K ++ LN AP+ +Y +Y +L+ I +I+DK +Y +FYSRW+ I + GK+YI+NIV Sbjct: 121 FFKKKNVMLNIAPMKATYKEYQQLQHQINVFIKDKVIYEKFYSRWSTIQLAGKFYIVNIV 180 Query: 182 PYYNRYLIGLISADNLIRPLRQINLGANGYASLVDENGTRISSPLSGSGKL--VQQEQGW 239 PY++ Y+I LI+AD+LIRPLRQINLG NGYASL E+G+ ++SP+S GKL + +EQ Sbjct: 181 PYHDSYMICLIAADDLIRPLRQINLGENGYASLRAEDGSLVTSPISNKGKLLNIAREQDR 240 Query: 240 PGL---LRSRTTISSEFSNTTFSADMVIQFGAFEKIMIAQLLIMLLFFIVTSTLCAVMLF 296 + L++RTT++ EF N +F +VIQFGAFEKIMI QLLIMLL IV +L +ML+ Sbjct: 241 SSVMNTLQTRTTVNGEFDNASFFVKLVIQFGAFEKIMIVQLLIMLLAVIVACSLSFIMLY 300 Query: 297 FNKRVLGPIQNFSENLAHMNEDGQPAGFKSSKIIELEQASDQFKDLMEQVKTFKIAIYEQ 356 F +VL PI++FS NLA EDG+P SKI+ELE+A+ QF L+ Q+KT+KI IYE+ Sbjct: 301 FKNKVLQPIKSFSYNLAFWAEDGEPLDSTGSKIVELEKANKQFAQLVNQIKTYKIDIYER 360 Query: 357 ELEKQRIQLDYMKQQIKPHFFLNCLTSIYSMAQIQMYEEIENMAMSTSKYFRYTFQDGGN 416 ELEKQRIQLDYMK QIKPHFFLNCLT+I+SMAQ+ M EEI+ MA+STS YFRY FQ+G + Sbjct: 361 ELEKQRIQLDYMKLQIKPHFFLNCLTTIHSMAQMDMTEEIQQMALSTSVYFRYIFQNGQD 420 Query: 417 FVRLEDEIEHIRIYLEIQRSRYRDAFRHHIVQDETAKDVQIPPLVLQTFIENSVKYAISR 476 FVRLEDEIEH+R+YLEIQR+RYR +F + I Q+E+ +DV IPPLVLQTFIEN++KYA+SR Sbjct: 421 FVRLEDEIEHVRVYLEIQRNRYRSSFLYRIEQEESTRDVPIPPLVLQTFIENAIKYAVSR 480 Query: 477 DPEVQISLTVTRRESEEEQVTVIQISDNGPGFAPEVLEKLVRGQPLDQSKGTHIGIMNTL 536 + EV I+LTV RR +EE+++TVIQI+D GPGF PE+LEKL G+PLDQ+ GT IGIMNT+ Sbjct: 481 EHEVLITLTVERRMTEEQRMTVIQITDTGPGFPPEILEKLQLGEPLDQTLGTQIGIMNTV 540 Query: 537 KRLEYLYYKKAAVHFSNIEGGGASVIITLPDLPATS 572 +RL+YLY + A + F N GGASV + LP+LPA S Sbjct: 541 QRLKYLYGELAQIDFDNQLNGGASVTLYLPELPANS 576 >B1DBE2.1 B1DBE2_9BACL Histidine kinase internal region Length = 578 Score = 223 bits (567), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 153/571 (26%), Positives = 286/571 (50%), Gaps = 26/571 (4%) Query: 15 HYVRIMILVSFAVLVLDLAI-----SLASISIVKQQSTRYLQDTAKLYIDRINHDFAYIN 69 H +R I++ ++V + +L SI +V+ Q ++ ++ LY+ I+ + I+ Sbjct: 11 HSIRFKIIIGLLIVVTPILFLLIYNNLYSIQLVRNQVSQSNKNMLHLYMGLIDKELEGID 70 Query: 70 HYMGWTLANDET-LNMMNAYEPDSSEFLK-SNSNLYKRFSELQKNYGQEYNFFFYLKNQS 127 Y+ + A +ET L ++ E D + + LY++ + + +Y F + N+ Sbjct: 71 DYL-FRFATEETGLLYLDRSETDDPDLYNLAKYRLYQQLYSVTGSVSLDYYFLYSPANRE 129 Query: 128 FFLNCAPISVSYTDYLELKKLIYSYIEDKDVYAEF-YSRWTPILVNGKYYIINIVPYYNR 186 L + D +++ + +E++ F Y +W+ + + GK Y I + N Sbjct: 130 LVLAPKNQAAESRDLDTIRQQLNHAVENQHRNPTFRYWKWSSLELGGKSYFIRLFKSGNV 189 Query: 187 YLIGLISADNLIRPLRQINLGANGYASLVDENGTRISSPLSGSGKL---------VQQEQ 237 Y+ L++ D ++ L +++LGA+G A ++D R P+ G+ + ++++ Sbjct: 190 YIGALVNYDRVMSALDELDLGASGQAVMLD----RDEQPIEGADWINDRHINVLALREDY 245 Query: 238 GWPGLLRSRTTISSEFSNTTFS-ADMVIQFGAFEKIMIAQLLIMLLFFIVTSTLCAVMLF 296 G ++ I + F+ A ++ EK+ + +I+L+ L LF Sbjct: 246 RMTGDVQRFMVIREQSGRGDFALAAILSDRSIIEKLPYKKRIIVLIALGTGGILLGAWLF 305 Query: 297 FNKRVLGPIQNFSENLAHMNEDGQPAGFK-SSKIIELEQASDQFKDLMEQVKTFKIAIYE 355 + VL P+ + M E + S +E E ++ F + Q++ KI IYE Sbjct: 306 LRRIVLIPVYRLMVAMRRMREGKLDTRMEVGSTSLEFELMNESFNSMASQIERLKIDIYE 365 Query: 356 QELEKQRIQLDYMKQQIKPHFFLNCLTSIYSMAQIQMYEEIENMAMSTSKYFRYTFQDGG 415 ++L +R +L +++ QI PHF+LN L + Y +A+ E I+ +++S +YFR+ F+ Sbjct: 366 EQLLSKRAELKHLQLQINPHFYLNSLNTFYYLAEDNKSEVIKELSLSLIRYFRFMFRGHS 425 Query: 416 NFVRLEDEIEHIRIYLEIQRSRYRDAFRHHIVQDETAKDVQIPPLVLQTFIENSVKYAIS 475 +FV + DEIEH+R YL IQ R+ + ++ I E D +IPPL++QTF+EN++K+A++ Sbjct: 426 DFVSVRDEIEHVRNYLRIQAFRFPEQMKYEIAVTEELLDARIPPLLVQTFVENAIKHAVT 485 Query: 476 RDPEVQISLTVTRRESEEEQVTVIQISDNGPGFAPEVLEKLVRGQPLDQSKGTHIGIMNT 535 D V I +T+ R ++ ++++ D+G GF EV+ K G+ L G IGI N Sbjct: 486 LDQPVTIFVTIRRLTDADDDPMLVRVYDDGSGFPEEVIRKFEEGESLLTEAGERIGIWNA 545 Query: 536 LKRLEYLYYKKAAVHFSNIEGGGASVIITLP 566 +RL LY +A++ SN GA + I LP Sbjct: 546 KQRLSLLYSGQASMAISN--SPGADIRIQLP 574 >B3KBX4.1 B3KBX4_9BACI Histidine kinase internal region Length = 587 Score = 198 bits (503), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 164/577 (28%), Positives = 279/577 (48%), Gaps = 40/577 (6%) Query: 20 MILVSFAVLVLDLAISLASISIVKQQSTRYLQDTAKLYIDRINHDFAYINHYMGWTLAND 79 ++LV ++ L ++ +I +V+ Q +D LY D+I+ + Y+ + Sbjct: 26 LLLVVMPLIGFLLYSNIYAIDVVRNQVASSNKDLLVLYRDQIDAKLKEADDYLIELMIGT 85 Query: 80 ETLNMMNAYEPD----SSEFLKSN-SNLYKRFSELQKNYGQEY---NFFFYLKNQSFFLN 131 + + A P+ +S+ + +N S+ R+S L Y E N+++ +++S Sbjct: 86 DLNELDYALNPEERFFASQRIAANLSSSISRYSVLDGLYVYEPSSDNYYYSFQSRS---- 141 Query: 132 CAPISVSYTDYLELKKLIYSYIEDKDVYAEF-YSRWTPILVNGKYYIINIVPYYNRYLIG 190 +Y D ++ +Y + E +W NG+ Y+I ++ N +G Sbjct: 142 ------TYEDRQYIRSHVYETFKAGASPLELNRKKWYVQNYNGQTYLIRLLKMKNGTTVG 195 Query: 191 -LISADNLIRPLRQINLGANGYASLVDENGTRISSP--LSGSGKLVQ---QEQGWPGLLR 244 ++A + PL +++G G A L+D+ G + + + SG VQ Q G Sbjct: 196 AWLNARSFQTPLELLSVGNKGAALLIDDRGKAMVNQTFIDDSGVEVQLNPQSYYLTGTSS 255 Query: 245 SRTTIS-----SEFSNTTFSADMVIQFGAFEKIMIAQLLIMLLFFIVTSTLCAVMLFFNK 299 T+ EFS F + I + + I + + LL F L ++ K Sbjct: 256 RYLTVGEHSRLGEFSLYAFIPEETI----LQHLPILKTISTLLPFGSVVILIIGLILLRK 311 Query: 300 RVLGPIQNFSENLAHMNE---DGQPAGFKSSKIIELEQASDQFKDLMEQVKTFKIAIYEQ 356 +L PI + + + D Q + +S IE +D F ++ Q+K+ +I IYE+ Sbjct: 312 WLLVPINRLLRAMNRIEQGHVDTQIREYPTS--IEFRVMNDTFNSMVGQIKSLRINIYEE 369 Query: 357 ELEKQRIQLDYMKQQIKPHFFLNCLTSIYSMAQIQMYEEIENMAMSTSKYFRYTFQDGGN 416 +L KQ+ +L +++ QIKPHF++N L I+++A+ IE+M++ +YFRY FQ Sbjct: 370 QLNKQKAELQHLQLQIKPHFYINALNMIHTLARRNDVRRIEDMSLYMVRYFRYMFQSNLT 429 Query: 417 FVRLEDEIEHIRIYLEIQRSRYRDAFRHHIVQDETAKDVQIPPLVLQTFIENSVKYAISR 476 FV L+DEI+HIR YL IQ R+ H I + +PPLV+QT +EN++K+AIS Sbjct: 430 FVSLKDEIQHIRNYLNIQELRFPGQIIHEIEVPDFLLRTPVPPLVMQTLVENAMKHAISL 489 Query: 477 DPEVQISLTVTRRESEEEQVTVIQISDNGPGFAPEVLEKLVRGQPLDQSKGTHIGIMNTL 536 D V++ + V ES E + +IQI D GPGF ++EK+ + + +G HIG N Sbjct: 490 DEPVRVQVRVEMDESPERGL-IIQIQDTGPGFKEGMIEKIAADERIIDEEGEHIGFWNLK 548 Query: 537 KRLEYLYYKKAAVHFSNIEGGGASVIITLPDLPATST 573 +RL LY +A V N++ GA V + LP P T Sbjct: 549 QRLRLLYGNRAKVELQNVQPHGAMVELKLPFSPDGGT 585 >B1DHJ7.1 B1DHJ7_9BACL Histidine kinase internal region Length = 585 Score = 179 bits (453), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 139/577 (24%), Positives = 265/577 (45%), Gaps = 35/577 (6%) Query: 17 VRIMILVSFAVLVLDLAI-----SLASISIVKQQSTRYLQDTAKLYIDRINHDFAYINHY 71 +R +++ F ++++ L I +L + +V Q + ++ +Y++ ++ I +Y Sbjct: 6 MRSRLILGFGLVIIPLVILLLWNNLYATKVVHSQVAQSNRNMLTMYMNDMDQVLGEIENY 65 Query: 72 MGWTLANDETLNMMNAYEPDSSEFLKSNSNLYKRFSELQKNYGQEYNFFF-YLKNQSFFL 130 + D++L ++ Y+ DS E+ S + +L NY + F Y L Sbjct: 66 LYKAAEQDQSLISLSQYDKDSWEYYLSTTQTANDL-DLNINYYDSADVLFAYGGKYKELL 124 Query: 131 NCAPISVSYTDYLELKKLIYSYIEDKDVYAEFYSRWTPILVNGKYYIINIVPY-YNRYLI 189 SV+Y E++ + + D + W + + G+Y ++ +V Y+ Y+ Sbjct: 125 VAQQQSVTYARKQEIQSKLKELLAGND--PALRAGWKVVELKGQYALVRVVDTNYDSYIG 182 Query: 190 GLISADNLIRPLRQINLGANGYASLVDENGTRISSPLSGSGKLVQQEQGWPGLLRSRTTI 249 I + L+ P+RQ+ G A LV G PLS G ++QE L Sbjct: 183 AWIDLNRLMEPIRQLGQGGKAEALLVSGEG----EPLSTVGTSIRQEVEAFDLTAYMDNG 238 Query: 250 SSEF------------SNTTFSADMVIQFGAFEKIMIAQLLIMLLFFIVTSTLCAVML-- 295 ++ + + ++ ADM + F E+ ++ L I + L A+ML Sbjct: 239 NAAYNIVKLGNPYLLVAKSSRMADMNLIFLLPERKLLEGLPIFRKMTYLIPMLAAIMLGL 298 Query: 296 ---FFNKRVLGPIQNFSENLAHMNEDGQPAGFKSSKIIELEQASDQFKDLMEQVKTFKIA 352 F ++ PI +F + + + + K+ E + F + +Q++ KI Sbjct: 299 YLLFLQNSIVKPIHHFIKGMRKIRSGDLSVRMEDYKLQEFITLKETFNGMAQQIEHLKID 358 Query: 353 IYEQELEKQRIQLDYMKQQIKPHFFLNCLTSIYSMAQIQMYEEIENMAMSTSKYFRYTFQ 412 IYE++L Q+ +L +++ QI PHFF+N L +Y +AQI+ YE I++M++ +YFR+T + Sbjct: 359 IYEEQLRTQKAELKHLQAQIHPHFFMNSLNIVYQLAQIKDYEVIQHMSLHLVRYFRFTTR 418 Query: 413 DGGNFVRLEDEIEHIRIYLEIQRSRYRDAFRHHIVQDETAKDVQIPPLVLQTFIENSV-- 470 + V +++E EHI YL IQ+ R+ + D + + IPPL +Q +EN++ Sbjct: 419 TQVSTVTVKEEAEHIFHYLSIQKYRFPETLAFDFQVDPALEKMSIPPLTIQPMVENAMVH 478 Query: 471 KYAISRDPEVQISLTVTRRESEEEQVTVIQISDNGPGFAPEVLEKL-VRGQPLDQSKGTH 529 ++I I + V+ E+ +I++ DNG G E +E L + L+ G+ Sbjct: 479 GFSIRTGSPFHIRVKVSAEGEGEDAELIIEVEDNGKGLTEEQMEHLRTKVHSLEPGDGS- 537 Query: 530 IGIMNTLKRLEYLYYKKAAVHFSNIEGGGASVIITLP 566 +G+ N ++R Y + F + GA V + +P Sbjct: 538 LGLWNVVRRCRLYYKGTVRMAFGGADPQGAVVTLRVP 574 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.136 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,221,303,260 Number of extensions: 134890796 Number of successful extensions: 412107 Number of sequences better than 1.0e-05: 1896 Number of HSP's gapped: 410386 Number of HSP's successfully gapped: 1898 Length of query: 573 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 432 Effective length of database: 1,732,333,088 Effective search space: 748367894016 Effective search space used: 748367894016 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 134 (56.2 bits)