BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0346.0010.p (491 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C2H7R2.1 C2H7R2_ENTFC Altronate dehydratase EC=4.2.1.7 713 0.0 Q3Y3F8.1 Q3Y3F8_ENTFC Altronate dehydratase EC=4.2.1.7 708 0.0 C1P817.1 C1P817_BACCO Altronate dehydratase EC=4.2.1.7 645 0.0 A9QSF7.1 A9QSF7_LACLA Altronate hydrolase EC=4.2.1.7 627 e-178 Q65F25.1 Q65F25_BACLD UxaA 627 e-178 >C2H7R2.1 C2H7R2_ENTFC Altronate dehydratase EC=4.2.1.7 Length = 499 Score = 713 bits (1840), Expect = 0.0, Method: Compositional matrix adjust. Identities = 336/491 (68%), Positives = 394/491 (80%) Query: 1 MKMNPRDTVAVALRPIASGEVLSFEGLSLTAAQDIPQGHKIALTSFAEGDVITKYGYPIG 60 MK+N RD+V VAL PI L+ + ++T +DIPQGHKIAL+ GD + KYGYPIG Sbjct: 9 MKLNQRDSVVVALTPIPKQTQLTIDQQTITTLEDIPQGHKIALSDLKAGDNVIKYGYPIG 68 Query: 61 HAVEEIRAGDWIHTHNIKTNLSGEEEYEYLPDLHPVTYPKRGLTFQGYRRANGKVGIRND 120 H ++ AG W+HTHN+KTNLSGE +Y Y D+HP YP TFQGY R NGKVGIRND Sbjct: 69 HVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVHPSHYPFENRTFQGYLRKNGKVGIRND 128 Query: 121 LFIIPTVGCVNGIAEQMLQEFKAEHPDLGGFDNFTVLKHPYGCSQLGDDHRMTRSILLDA 180 LF++PTVGCVNGIAE ++++FK +HPDLG FD+ T+LKHPYGCSQLG DH+ TR IL DA Sbjct: 129 LFLVPTVGCVNGIAELIVKQFKEKHPDLGQFDHITILKHPYGCSQLGKDHQNTREILADA 188 Query: 181 VNHPNAGGVLVFGLGCENNIVSEFRSMLGDYDGSRVKFLVAQEVGDEVXXXXXXXXXXXX 240 VNHPNAGGVLVFGLGCENN V EF+ +LG+YD RVKFLVAQ+V DE+ Sbjct: 189 VNHPNAGGVLVFGLGCENNTVPEFKKILGEYDEERVKFLVAQDVYDEIEQGVALLEELLT 248 Query: 241 XXKNDVREPVPLSELNIGLKCGGSDGFSGITANPLLGAFSDFIISQGGTSVLTEVPEMFG 300 +ND R PVPLS+LN+GLKCGGSDG SGITANPLLGAFSD++I+QGG+++LTEVPEMFG Sbjct: 249 AVENDQRIPVPLSKLNVGLKCGGSDGLSGITANPLLGAFSDYLIAQGGSTILTEVPEMFG 308 Query: 301 AEKMLMARAENREVFEDIVSLINNFKQYFLSYGEPVYENPSPGNKAGGISTLEDKSLGCT 360 AE++LMARAEN +VF IV LIN+FKQYFLSYGEPVYENPSPGNKAGGI+TLEDKSLGCT Sbjct: 309 AEQVLMARAENEKVFGSIVDLINDFKQYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCT 368 Query: 361 QKAGSSPVVDVLDYGVKLRRKGLSLLQAPGNXXXXXXXXXXXXCQLVLFTTGRGTPFGSF 420 QK+GSSPVVDVL YG K+R+ GLSLLQAPGN CQLVLFTTGRGTPFGS+ Sbjct: 369 QKSGSSPVVDVLQYGEKIRKPGLSLLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSY 428 Query: 421 VPTVKVATNNDLFAKKGHWMDFNAGPLLERPMADVLEEFIAYIIDVASGQKTRNEQNEVR 480 VPTVKV+TN LF +KGHWMDFNAG LLE+PM +LE F+ II VASG++T+NEQN+VR Sbjct: 429 VPTVKVSTNTTLFERKGHWMDFNAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVR 488 Query: 481 ELAIFKTGVTL 491 E+AIFK GVTL Sbjct: 489 EIAIFKNGVTL 499 >Q3Y3F8.1 Q3Y3F8_ENTFC Altronate dehydratase EC=4.2.1.7 Length = 499 Score = 708 bits (1828), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/491 (68%), Positives = 392/491 (79%) Query: 1 MKMNPRDTVAVALRPIASGEVLSFEGLSLTAAQDIPQGHKIALTSFAEGDVITKYGYPIG 60 MK+N RD+V VAL PI L+ + ++T +DIPQGHKIAL GD + KYGYPIG Sbjct: 9 MKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIPQGHKIALGDLKAGDNVIKYGYPIG 68 Query: 61 HAVEEIRAGDWIHTHNIKTNLSGEEEYEYLPDLHPVTYPKRGLTFQGYRRANGKVGIRND 120 H ++ AG W+HTHN+KTNLSGE +Y Y D+HP Y TFQGY R NGKVGIRND Sbjct: 69 HVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVHPSHYLFENRTFQGYLRKNGKVGIRND 128 Query: 121 LFIIPTVGCVNGIAEQMLQEFKAEHPDLGGFDNFTVLKHPYGCSQLGDDHRMTRSILLDA 180 LF++PTVGCVNGIAE ++++FK +HPDLG FD+ T+LKHPYGCSQLG DH+ TR IL DA Sbjct: 129 LFLVPTVGCVNGIAELIVKQFKEKHPDLGQFDHITILKHPYGCSQLGKDHQNTREILADA 188 Query: 181 VNHPNAGGVLVFGLGCENNIVSEFRSMLGDYDGSRVKFLVAQEVGDEVXXXXXXXXXXXX 240 VNHPNAGGVLVFGLGCENN V EF+ +LG+YD RVKFLVAQ+V DE+ Sbjct: 189 VNHPNAGGVLVFGLGCENNTVPEFKKILGEYDEERVKFLVAQDVYDEIEQGVALLEELLT 248 Query: 241 XXKNDVREPVPLSELNIGLKCGGSDGFSGITANPLLGAFSDFIISQGGTSVLTEVPEMFG 300 +ND R VPLS+LN+GLKCGGSDG SGITANPLLGAFSD++I+QGG+++LTEVPEMFG Sbjct: 249 AAENDQRISVPLSKLNVGLKCGGSDGLSGITANPLLGAFSDYLIAQGGSTILTEVPEMFG 308 Query: 301 AEKMLMARAENREVFEDIVSLINNFKQYFLSYGEPVYENPSPGNKAGGISTLEDKSLGCT 360 AE++LMARAEN EVF+ IV LIN+FKQYFLSYGEPVYENPSPGNKAGGI+TLEDKSLGCT Sbjct: 309 AEQVLMARAENEEVFDSIVDLINDFKQYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCT 368 Query: 361 QKAGSSPVVDVLDYGVKLRRKGLSLLQAPGNXXXXXXXXXXXXCQLVLFTTGRGTPFGSF 420 QK+GSSPVVDVL YG K+R+ GLSLLQAPGN CQLVLFTTGRGTPFGS+ Sbjct: 369 QKSGSSPVVDVLQYGEKIRKPGLSLLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSY 428 Query: 421 VPTVKVATNNDLFAKKGHWMDFNAGPLLERPMADVLEEFIAYIIDVASGQKTRNEQNEVR 480 VPTVKV+TN LF +KGHWMDFNAG LLE+PM +LE F+ II VASG++T+NEQN+VR Sbjct: 429 VPTVKVSTNTTLFERKGHWMDFNAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVR 488 Query: 481 ELAIFKTGVTL 491 E+AIFK GVTL Sbjct: 489 EIAIFKNGVTL 499 >C1P817.1 C1P817_BACCO Altronate dehydratase EC=4.2.1.7 Length = 496 Score = 645 bits (1664), Expect = 0.0, Method: Compositional matrix adjust. Identities = 304/490 (62%), Positives = 372/490 (75%) Query: 1 MKMNPRDTVAVALRPIASGEVLSFEGLSLTAAQDIPQGHKIALTSFAEGDVITKYGYPIG 60 +++NPRD V VAL+ + G+VL+ ++T + I +GHKIAL E I KYG PIG Sbjct: 6 IQLNPRDNVLVALQDLEPGDVLTSGDRAITVNEAIKRGHKIALEDIEENADIIKYGSPIG 65 Query: 61 HAVEEIRAGDWIHTHNIKTNLSGEEEYEYLPDLHPVTYPKRGLTFQGYRRANGKVGIRND 120 HA ++I G W+HTHN+ TNLSG+ EYEY P+LHP +PK TF+GY R NGK GIRND Sbjct: 66 HATKKIEQGSWVHTHNVSTNLSGKVEYEYKPELHPRIFPKDSRTFKGYLRKNGKAGIRND 125 Query: 121 LFIIPTVGCVNGIAEQMLQEFKAEHPDLGGFDNFTVLKHPYGCSQLGDDHRMTRSILLDA 180 L+IIPTVGC+N I + ++ +FKA HPD G FD + KHPYGCSQLGDD + TR IL+DA Sbjct: 126 LYIIPTVGCINMIGDLLVDQFKANHPDNGAFDEIILFKHPYGCSQLGDDLQNTRKILMDA 185 Query: 181 VNHPNAGGVLVFGLGCENNIVSEFRSMLGDYDGSRVKFLVAQEVGDEVXXXXXXXXXXXX 240 HPNAGGVL+FGLGCENN + E ++ +G++D RVKF++ Q+V DEV Sbjct: 186 AAHPNAGGVLIFGLGCENNQLDEMKAQMGEFDEKRVKFMICQDVEDEVETGFQLLEELNE 245 Query: 241 XXKNDVREPVPLSELNIGLKCGGSDGFSGITANPLLGAFSDFIISQGGTSVLTEVPEMFG 300 K D R +PLSEL IGLKCGGSDGFSGIT NPLLG FSDF+ISQGG++VLTEVPEMFG Sbjct: 246 AAKEDKRIDLPLSELKIGLKCGGSDGFSGITGNPLLGRFSDFVISQGGSTVLTEVPEMFG 305 Query: 301 AEKMLMARAENREVFEDIVSLINNFKQYFLSYGEPVYENPSPGNKAGGISTLEDKSLGCT 360 AEKMLMARA++ VF IV LIN FK YF SYG+P+YENPSPGNKAGGI+TLEDKSLGCT Sbjct: 306 AEKMLMARAKDEIVFNKIVKLINQFKDYFASYGQPIYENPSPGNKAGGITTLEDKSLGCT 365 Query: 361 QKAGSSPVVDVLDYGVKLRRKGLSLLQAPGNXXXXXXXXXXXXCQLVLFTTGRGTPFGSF 420 QKAG+S VVDVL+YG KL+ KGLSLLQAPGN CQ+VLFTTGRGTPFG+F Sbjct: 366 QKAGTSAVVDVLEYGEKLKEKGLSLLQAPGNDLVSSTALAAADCQMVLFTTGRGTPFGTF 425 Query: 421 VPTVKVATNNDLFAKKGHWMDFNAGPLLERPMADVLEEFIAYIIDVASGQKTRNEQNEVR 480 VPTVKV+TN +L+ KK W+DFNAG LL+ M +V+E+FI++I++VASG+KT+NE + Sbjct: 426 VPTVKVSTNTELYEKKKQWIDFNAGRLLDEEMDEVVEQFISFILEVASGKKTKNEIRHLH 485 Query: 481 ELAIFKTGVT 490 E+AIFK GVT Sbjct: 486 EIAIFKNGVT 495 >A9QSF7.1 A9QSF7_LACLA Altronate hydrolase EC=4.2.1.7 Length = 496 Score = 627 bits (1617), Expect = e-178, Method: Compositional matrix adjust. Identities = 303/490 (61%), Positives = 365/490 (74%), Gaps = 1/490 (0%) Query: 3 MNPRDTVAVALRPIASGEVLSFEGLSLTAAQDIPQGHKIALTSFAEGDVITKYGYPIGHA 62 +NP D VAVALR I GE ++ +S D+P+GHKIAL F + D +TKYG PIGH Sbjct: 7 LNPLDNVAVALRDIKKGEGVTDGAISTLVVTDVPRGHKIALRDFKKNDDVTKYGAPIGHV 66 Query: 63 VEEIRAGDWIHTHNIKTNLSGEEEYEYLPDLHPVTYPKRGLTFQGYRRANGKVGIRNDLF 122 EE+ G WIH+HN+KTNL GE +Y Y PD PVTYPK TF+GYRRA+G+VG+RNDL+ Sbjct: 67 TEEVVKGTWIHSHNMKTNLEGELKYSYEPDFKPVTYPKVDRTFKGYRRADGRVGVRNDLY 126 Query: 123 IIPTVGCVNGIAEQMLQEFKAEHP-DLGGFDNFTVLKHPYGCSQLGDDHRMTRSILLDAV 181 I+P VGCVNGIAE +L++FK +H + FDN +LKH YGCSQLGDDH TR +L DAV Sbjct: 127 IVPMVGCVNGIAEIVLEQFKEKHRGEKLPFDNIIILKHEYGCSQLGDDHENTRRVLADAV 186 Query: 182 NHPNAGGVLVFGLGCENNIVSEFRSMLGDYDGSRVKFLVAQEVGDEVXXXXXXXXXXXXX 241 +HPNAGGVLVFGLGCENN + F+ ++G D SRVKFLVAQ V +E Sbjct: 187 HHPNAGGVLVFGLGCENNTMDAFKVLVGKVDHSRVKFLVAQHVKNEQKSANDLLEEILEA 246 Query: 242 XKNDVREPVPLSELNIGLKCGGSDGFSGITANPLLGAFSDFIISQGGTSVLTEVPEMFGA 301 KND RE +PL EL +GLKCGGSDGFSGITANPL+G FSD++ +QGG+SVLTEVPEMFGA Sbjct: 247 AKNDHREEIPLYELTVGLKCGGSDGFSGITANPLIGMFSDYLGAQGGSSVLTEVPEMFGA 306 Query: 302 EKMLMARAENREVFEDIVSLINNFKQYFLSYGEPVYENPSPGNKAGGISTLEDKSLGCTQ 361 E LMARAEN EVF IV LIN+FK+YF SYG+PV+ENPSPGNK GGI+TLEDKSLGCTQ Sbjct: 307 ETRLMARAENEEVFTSIVHLINDFKRYFKSYGQPVFENPSPGNKEGGITTLEDKSLGCTQ 366 Query: 362 KAGSSPVVDVLDYGVKLRRKGLSLLQAPGNXXXXXXXXXXXXCQLVLFTTGRGTPFGSFV 421 K+G++ VVDVL Y +R+KGLSLLQ PGN ++LF+TGRGTPFG+FV Sbjct: 367 KSGTAKVVDVLTYAQPIRKKGLSLLQGPGNDLVSTTNMAAAGVNMILFSTGRGTPFGTFV 426 Query: 422 PTVKVATNNDLFAKKGHWMDFNAGPLLERPMADVLEEFIAYIIDVASGQKTRNEQNEVRE 481 PT+K+ATNN+L KK HW+DFNAG L V E+FI II VASG+ TRNE+N+ +E Sbjct: 427 PTLKIATNNELGQKKDHWIDFNAGRLFNEDKEVVFEDFIEKIIAVASGEATRNEENKFQE 486 Query: 482 LAIFKTGVTL 491 +AIFK GVTL Sbjct: 487 IAIFKNGVTL 496 >Q65F25.1 Q65F25_BACLD UxaA Length = 496 Score = 627 bits (1616), Expect = e-178, Method: Compositional matrix adjust. Identities = 304/492 (61%), Positives = 371/492 (75%), Gaps = 1/492 (0%) Query: 1 MKMNPRDTVAVALRPIASGEVLSFEGLSLTAAQDIPQGHKIALTSFAEGDVITKYGYPIG 60 + +NP+D V +ALR + +GE ++ ++ + I +GHK AL AE + + KYG+PIG Sbjct: 5 LMINPQDNVGIALRELQTGETVTVGERTIVIKEPILKGHKFALKDIAENENVIKYGFPIG 64 Query: 61 HAVEEIRAGDWIHTHNIKTNLSGEEEYEYLPDLHPVTYPKRGLTFQGYRRANGKVGIRND 120 HA E I+ G+W+HT N+KTNL G EEY Y P Y K LTF+G++R +GK GIRN+ Sbjct: 65 HATEMIQTGEWVHTKNVKTNLGGVEEYSYKPKFTENRYQKEPLTFKGFKRKDGKTGIRNE 124 Query: 121 LFIIPTVGCVNGIAEQMLQEFKAEHPDLGGFDNFTVLKHPYGCSQLGDDHRMTRSILLDA 180 L+I+PTVGCVNGIAE +++EFKAE + F++ VLKH YGCSQLGDDH TR+IL +A Sbjct: 125 LWIVPTVGCVNGIAELIIKEFKAEVGSIAPFESVHVLKHQYGCSQLGDDHINTRTILANA 184 Query: 181 VNHPNAGGVLVFGLGCENNIVSEFRSMLGDYDGSRVKFLVAQEVGDEVXXXXXXXXXXXX 240 VNHPNAGGVLV GLGCENN + EFR LGDYD SRVKFL++QEV +EV Sbjct: 185 VNHPNAGGVLVLGLGCENNSIHEFREALGDYDHSRVKFLLSQEVSNEVTEGVKLLKEIYK 244 Query: 241 XXKNDVREPVPLSELNIGLKCGGSDGFSGITANPLLGAFSDFIISQGGTSVLTEVPEMFG 300 K D RE VPLSEL IGLKCGGSDGFSGITANPLLG SDF+I+QGGT+VLTEVPEMFG Sbjct: 245 HAKGDHREDVPLSELKIGLKCGGSDGFSGITANPLLGRLSDFLIAQGGTAVLTEVPEMFG 304 Query: 301 AEKMLMARAENREVFEDIVSLINNFKQYFLSYGEPVYENPSPGNKAGGISTLEDKSLGCT 360 AE +LM RAEN EVF IV LIN+FKQYF+ + +PVYENPSPGNKAGGI+TLEDKSLGCT Sbjct: 305 AETLLMERAENEEVFHKIVRLINDFKQYFIDHRQPVYENPSPGNKAGGITTLEDKSLGCT 364 Query: 361 QKAGSSPVVDVLDYGVKLRRKGLSLLQAPGNXXXXXXXXXXXXCQLVLFTTGRGTPFGSF 420 QKAG+S V DVL+YG L++KGL+LL APGN CQ+VLFTTGRGTPFG+F Sbjct: 365 QKAGTSKVADVLEYGDVLKKKGLNLLSAPGNDLVASSALAAAGCQIVLFTTGRGTPFGTF 424 Query: 421 VPTVKVATNNDLFAKKGHWMDFNAGPLLE-RPMADVLEEFIAYIIDVASGQKTRNEQNEV 479 VPT+K++TN ++ K HW+DFNAG +LE R DVL+E AY+I+VASG++ NE N+ Sbjct: 425 VPTMKISTNTAIYEAKRHWIDFNAGKVLEDRSEDDVLKELTAYLIEVASGRQLNNEINDF 484 Query: 480 RELAIFKTGVTL 491 RELAIFKTGVTL Sbjct: 485 RELAIFKTGVTL 496 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.138 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,920,639,744 Number of extensions: 123899900 Number of successful extensions: 252688 Number of sequences better than 1.0e-05: 758 Number of HSP's gapped: 250411 Number of HSP's successfully gapped: 857 Length of query: 491 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 351 Effective length of database: 1,741,754,103 Effective search space: 611355690153 Effective search space used: 611355690153 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 133 (55.8 bits)