BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0345.0015.p (430 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KHL0.1 B3KHL0_9BACI DNA-directed DNA polymerase EC=2.7.7.7 679 0.0 Q2B6E1.1 Q2B6E1_9BACI DNA polymerase IV 386 e-105 C1PES0.1 C1PES0_BACCO DNA-directed DNA polymerase EC=2.7.7.7 376 e-102 A8VXF9.1 A8VXF9_9BACI Propionyl-CoA carboxylase EC=6.4.1.3 375 e-102 A6CMS9.1 A6CMS9_9BACI DNA polymerase IV EC=2.7.7.7 361 8e-98 >B3KHL0.1 B3KHL0_9BACI DNA-directed DNA polymerase EC=2.7.7.7 Length = 443 Score = 679 bits (1752), Expect = 0.0, Method: Compositional matrix adjust. Identities = 318/417 (76%), Positives = 363/417 (87%) Query: 4 VDQYYPASGRVILHVDMNAFYCSVHEAEDPDQYKGKATAVAGSVELRRGIIVTCSYAARR 63 +D YYPASGRVILHVDMNAFYCSVHEAE+P+ Y+GKATAVAGS+ELR+G+IVTCSYAAR Sbjct: 4 IDDYYPASGRVILHVDMNAFYCSVHEAEEPELYRGKATAVAGSIELRKGVIVTCSYAARS 63 Query: 64 LGISTGMQVQKALRICPSLLLIKPDFHLYRKYSNAFMQIAYSYTPLLEAVSIDECYLDIT 123 LGI TGM V++ALRI P L++I+PDFHLYRKYSNAFM IAY+YTP LEA SIDECYLDIT Sbjct: 64 LGIRTGMNVRQALRIYPDLMIIQPDFHLYRKYSNAFMNIAYAYTPQLEATSIDECYLDIT 123 Query: 124 GSRQFGTPLEIAEGIQRRIMEELGLPCSIGIAPNKLLAKIASDLKKPNGISILRLRDVPD 183 GS+QFGTPL+IA IQ RI EEL LPCS+GIAPNKLLAK+ASD+KKPNG+S+LR+RDVP Sbjct: 124 GSKQFGTPLDIAREIQERIREELSLPCSVGIAPNKLLAKMASDMKKPNGLSVLRIRDVPQ 183 Query: 184 ILWDKPCNEMFGIGGKTAEKLRKLGIYSIGQLAAADERMLVEHFGVMGSWLKRAGNGIDH 243 +LW+KPC E+FGIG KTA+KLRKL I +IGQLAAADE +L FGVMGSW+KRA +GIDH Sbjct: 184 VLWNKPCAELFGIGSKTADKLRKLNIQTIGQLAAADESLLTSTFGVMGSWMKRAASGIDH 243 Query: 244 GVVNPEREQSKSIGHTTTLPSDVVGLAEARPVLLNLSDQVARRLRKQGLVASGVQLTIRT 303 V EREQSKSIGHTTTLP DV EAR VLLNLSDQVARRLR+QGLV SG+Q+T+RT Sbjct: 244 APVVAEREQSKSIGHTTTLPQDVTSAEEARRVLLNLSDQVARRLRRQGLVTSGIQITLRT 303 Query: 304 PDMKTITRSRQLETPTESAEDIYKTACDQFARHWKGDKPVRLLGVTLQGLTAKEDSAIQL 363 PDMKTITRSR L PTE+ EDIY+ AC+ + RHWK DKP+RLLGVTLQ LTAKE+SAIQL Sbjct: 304 PDMKTITRSRHLAIPTENTEDIYREACELYNRHWKQDKPLRLLGVTLQQLTAKEESAIQL 363 Query: 364 DLFNYERQPKKESLNKAMDMLRNKFGENAVLTAGMLSDSHSARLRNHKERGTSLQKD 420 DLF+YE+QPKKESL + MD LRNKFGE+AVLTAGML D S+ +RNHK RGTSLQ D Sbjct: 364 DLFDYEKQPKKESLTRVMDELRNKFGESAVLTAGMLGDDPSSLIRNHKRRGTSLQMD 420 >Q2B6E1.1 Q2B6E1_9BACI DNA polymerase IV Length = 432 Score = 386 bits (992), Expect = e-105, Method: Compositional matrix adjust. Identities = 208/419 (49%), Positives = 274/419 (65%), Gaps = 6/419 (1%) Query: 6 QYYPASGRVILHVDMNAFYCSVHEAEDPDQYKGKATAVAGSVELRRGIIVTCSYAARRLG 65 + YP +GRVILHVDMN+FY SV A +P + KGK A+AG+ E RRGIIVTCSY AR+ G Sbjct: 3 ELYPKNGRVILHVDMNSFYASVEMAYNP-ELKGKPLAIAGNAEERRGIIVTCSYEARKFG 61 Query: 66 ISTGMQVQKALRICPSLLLIKPDFHLYRKYSNAFMQIAYSYTPLLEAVSIDECYLDITGS 125 + T M + +A ++CP L+++ P+F YR S I Y+ L+E VSIDE Y+DIT S Sbjct: 62 VRTTMPLWEAKKLCPQLIVMTPNFERYRAASMGMFNILGQYSGLVEPVSIDEGYVDITDS 121 Query: 126 RQFGTPLEIAEGIQRRIMEELGLPCSIGIAPNKLLAKIASDLKKPNGISILRLRDVPDIL 185 ++G PLEIA IQ++I+++L LPCSIG+APNK LAK+ASD+KKP GI++LR RD+ +IL Sbjct: 122 YEYGAPLEIAGSIQKQILDQLDLPCSIGVAPNKFLAKMASDMKKPMGITVLRKRDIGNIL 181 Query: 186 WDKPCNEMFGIGGKTAEKLRKLGIYSIGQLAAADERMLVEHFGVMGSWLKRAGNGIDHGV 245 W P M G+G KTAEKLR L I +IG LA A++ L G+ G LK NGID Sbjct: 182 WPMPVEVMHGVGKKTAEKLRTLQIETIGSLAEANDLQLKGLLGINGPRLKERANGIDRRP 241 Query: 246 VNPER-EQSKSIGHTTTLPSDVVGLAEARPVLLNLSDQVARRLRKQGLVASGVQLTIRTP 304 V+PE + KS+G++TTLP DV E VL LS++VA RL+K+ + AS + +TIR Sbjct: 242 VDPESAAEFKSVGNSTTLPRDVSNQQELFKVLDMLSEKVAVRLKKKKVYASALGITIRYK 301 Query: 305 DMKTITRSRQLETPTESAEDIYKTACDQFARHWKGDKPVRLLGVTLQGLTAKEDSAIQLD 364 D KTITRSR+L+ P ED+ + F RHW GD PVRLLGVT Q L ++ + QLD Sbjct: 302 DRKTITRSRKLDNPVSLKEDLAAFSRKLFIRHWNGD-PVRLLGVTAQELVEQDQAVRQLD 360 Query: 365 LFNYERQPKKESLNKAMDMLRNKFGENAVLTAGMLSDSHSARLRNHKERGTSLQKDNLH 423 LF+YE++ +KE L K + LR KFG+ + AG D + TS KD LH Sbjct: 361 LFSYEKEARKEPLFKTLADLRTKFGDKIIDLAGAGGDEADKPVIGTD---TSFNKDFLH 416 >C1PES0.1 C1PES0_BACCO DNA-directed DNA polymerase EC=2.7.7.7 Length = 404 Score = 376 bits (965), Expect = e-102, Method: Compositional matrix adjust. Identities = 197/391 (50%), Positives = 260/391 (66%), Gaps = 3/391 (0%) Query: 7 YYPASGRVILHVDMNAFYCSVHEAEDPDQYKGKATAVAGSVELRRGIIVTCSYAARRLGI 66 +YP +GRVILHVDMN+F+ SV AE+P KGK AVAG+ + R+GIIVTCSY AR+ G+ Sbjct: 4 FYPKNGRVILHVDMNSFFASVEMAENP-ALKGKPLAVAGNPKERKGIIVTCSYEARKFGV 62 Query: 67 STGMQVQKALRICPSLLLIKPDFHLYRKYSNAFMQIAYSYTPLLEAVSIDECYLDITGSR 126 T M V +A + CP LL++ P F LY+K S I +Y+PL+E VSIDE Y+DITG Sbjct: 63 KTTMPVWEAKKRCPDLLIVPPRFDLYKKASAEMFSILRAYSPLVEPVSIDEGYVDITGLE 122 Query: 127 QFGTPLEIAEGIQRRIMEELGLPCSIGIAPNKLLAKIASDLKKPNGISILRLRDVPDILW 186 + GTP IAE IQ++I+ EL LP SIGIAPNK LAK ASD+KKP GI+ILR RD+P +LW Sbjct: 123 ELGTPPAIAESIQQQILAELDLPSSIGIAPNKFLAKTASDMKKPMGITILRKRDIPRLLW 182 Query: 187 DKPCNEMFGIGGKTAEKLRKLGIYSIGQLAAADERMLVEHFGVMGSWLKRAGNGIDHGVV 246 +P EM G+GGKTAEKL G+++IG LA AD+ +L + G+ G LK NG D V Sbjct: 183 PRPLIEMHGVGGKTAEKLNGCGLFTIGDLAHADDFLLKQLLGIRGIRLKERANGRDPRPV 242 Query: 247 NPEREQ-SKSIGHTTTLPSDVVGLAEARPVLLNLSDQVARRLRKQGLVASGVQLTIRTPD 305 +PE +KS+G TL D + VL L+D+ A R+RK+ + A+ V + IR D Sbjct: 243 DPESVNVTKSVGRMVTLSKDTGDEHQIDAVLKKLADETAERMRKKEVAATNVGIMIRYAD 302 Query: 306 MKTITRSRQLETPTESAEDIYKTACDQFARHWKGDKPVRLLGVTLQGLTAKEDSAIQLDL 365 KT+TRS++ P ES + +++ A F R+W G +PVRLLG+T GLT ++ A QL L Sbjct: 303 RKTVTRSKKSGGPVESGDALFQAARTLFIRNWNG-QPVRLLGITASGLTDRKAEAEQLSL 361 Query: 366 FNYERQPKKESLNKAMDMLRNKFGENAVLTA 396 F+YE KKE L +A+ LR KFGE + T Sbjct: 362 FSYEEAAKKEPLYEAISRLRKKFGEQIIQTG 392 >A8VXF9.1 A8VXF9_9BACI Propionyl-CoA carboxylase EC=6.4.1.3 Length = 429 Score = 375 bits (963), Expect = e-102, Method: Compositional matrix adjust. Identities = 206/413 (49%), Positives = 264/413 (63%), Gaps = 5/413 (1%) Query: 13 RVILHVDMNAFYCSVHEAEDPDQYKGKATAVAGSVELRRGIIVTCSYAARRLGISTGMQV 72 R+I HVDMN+FY SV A DP +GK A+AG+ + RRGI+VT SY AR G+ M + Sbjct: 5 RIIFHVDMNSFYASVEAAYDP-SLRGKPLAIAGNAKERRGIVVTASYEARAKGVKPPMPL 63 Query: 73 QKALRICPSLLLIKPDFHLYRKYSNAFMQIAYSYTPLLEAVSIDECYLDITGSRQFGTP- 131 +A + CP LL+ PDF YR S +I YSYTPL+E VSIDE Y+D+T GT Sbjct: 64 WEAEKACPGLLVRPPDFDRYRTMSRKMFEILYSYTPLVEPVSIDEGYMDVTNVHFEGTHG 123 Query: 132 LEIAEGIQRRIMEELGLPCSIGIAPNKLLAKIASDLKKPNGISILRLRDVPDILWDKPCN 191 LE+A+ IQ I +L LP SIG+APNK LAK+ASD+KKP GI++LR R+VPDILW Sbjct: 124 LELAKIIQDHIYHDLHLPSSIGVAPNKFLAKMASDMKKPMGITVLRKREVPDILWPLRAV 183 Query: 192 EMFGIGGKTAEKLRKLGIYSIGQLAAADERMLVEHFGVMGSWLKRAGNGIDHGVVNPER- 250 EM G+G KTA+KL +LG+++I LA AD L E FGV G + NGID V+PE Sbjct: 184 EMHGVGEKTADKLSRLGLFTIEDLAKADPFFLTEKFGVAGKRMHEKANGIDFRPVDPESI 243 Query: 251 EQSKSIGHTTTLPSDVVGLAEARPVLLNLSDQVARRLRKQGLVASGVQLTIRTPDMKTIT 310 KSIG++TTLP D + +L NLSD V+RRL+K+ + A +QLTIR D KTIT Sbjct: 244 HDFKSIGNSTTLPKDTANRQDITRILRNLSDSVSRRLKKKDVYAGNIQLTIRYHDRKTIT 303 Query: 311 RSRQLETPTESAEDIYKTACDQFARHWKGDKPVRLLGVTLQGLTAKEDSAIQLDLFNYER 370 RS++L P + +DIY A F +W G + VRLLGVT L K + LDLFNYE Sbjct: 304 RSKKLSYPVDGTDDIYDQAKQLFHDYWNG-RSVRLLGVTGMDLVEKGHAVKPLDLFNYEE 362 Query: 371 QPKKESLNKAMDMLRNKFGENAVLTAGMLSD-SHSARLRNHKERGTSLQKDNL 422 KKE L + +R KFGE+A+L + D + S +LR+ K RGTSL+KD L Sbjct: 363 DVKKERLQSMIGEIRGKFGEHALLRGTQIGDETASDQLRDQKGRGTSLEKDFL 415 >A6CMS9.1 A6CMS9_9BACI DNA polymerase IV EC=2.7.7.7 Length = 417 Score = 361 bits (927), Expect = 8e-98, Method: Compositional matrix adjust. Identities = 186/388 (47%), Positives = 259/388 (66%), Gaps = 3/388 (0%) Query: 7 YYPASGRVILHVDMNAFYCSVHEAEDPDQYKGKATAVAGSVELRRGIIVTCSYAARRLGI 66 +YP +GRVILHVDMN+FY SV A +P + KGK A+AG+ + RRGIIVTCSY AR G+ Sbjct: 4 HYPKNGRVILHVDMNSFYASVEAAYNP-ELKGKPLAIAGNPDERRGIIVTCSYEARGYGV 62 Query: 67 STGMQVQKALRICPSLLLIKPDFHLYRKYSNAFMQIAYSYTPLLEAVSIDECYLDITGSR 126 T M + +A ++CP L++++P+F YR S +I Y+ L+E VSIDE Y+DIT S Sbjct: 63 KTTMPLWEAKKLCPQLIIMRPNFDRYRAASQGMFEILRQYSQLVEPVSIDEGYVDITDSY 122 Query: 127 QFGTPLEIAEGIQRRIMEELGLPCSIGIAPNKLLAKIASDLKKPNGISILRLRDVPDILW 186 G+PL IAE IQ +I+ + LP SIGIAPNK LAK ASD+KKP GI++LR RD+P+ +W Sbjct: 123 SLGSPLFIAESIQNQILSQQDLPSSIGIAPNKFLAKTASDMKKPMGITVLRKRDLPERIW 182 Query: 187 DKPCNEMFGIGGKTAEKLRKLGIYSIGQLAAADERMLVEHFGVMGSWLKRAGNGIDHGVV 246 EM GIG KTA+KL + I++IG+LA A+E +L G+ G LK NG D V Sbjct: 183 PLDVKEMHGIGEKTAQKLYSMEIHTIGELAKANEIVLKSQLGINGLRLKARANGTDDRPV 242 Query: 247 NPEREQS-KSIGHTTTLPSDVVGLAEARPVLLNLSDQVARRLRKQGLVASGVQLTIRTPD 305 +P+ KS+G++TTLP D E L LS +VA R++ + ++A V LT+R D Sbjct: 243 DPDSVYDFKSVGNSTTLPRDTANQKELLNTLNQLSGKVASRMKSKDILALTVMLTMRFKD 302 Query: 306 MKTITRSRQLETPTESAEDIYKTACDQFARHWKGDKPVRLLGVTLQGLTAKEDSAIQLDL 365 KTITRS++L+ P S +DI+ A F +HW G+ +RLLGVT Q L ++D+A+QLD+ Sbjct: 303 RKTITRSKKLKNPVGSQDDIFAAAKALFLQHWNGNS-IRLLGVTGQDLVERDDAALQLDI 361 Query: 366 FNYERQPKKESLNKAMDMLRNKFGENAV 393 F+YE KKE L + ++ L++KFG+ + Sbjct: 362 FSYEEHAKKEPLYQTIEKLQDKFGKQMI 389 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.135 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,504,373,880 Number of extensions: 103173080 Number of successful extensions: 247413 Number of sequences better than 1.0e-05: 2633 Number of HSP's gapped: 240596 Number of HSP's successfully gapped: 2708 Length of query: 430 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 291 Effective length of database: 1,751,175,118 Effective search space: 509591959338 Effective search space used: 509591959338 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 133 (55.8 bits)