BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0342.0013.p (505 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DLK1.1 B1DLK1_9BACL Glucose-6-phosphate 1-dehydrogenase EC=1.1... 687 0.0 B7IPP8.1 B7IPP8_BACC2 Glucose-6-phosphate 1-dehydrogenase EC=1.1... 617 e-174 B5ULI3.1 B5ULI3_BACCE Glucose-6-phosphate 1-dehydrogenase EC=1.1... 615 e-174 Q3EVW4.1 Q3EVW4_BACTI Glucose-6-phosphate 1-dehydrogenase EC=1.1... 615 e-174 B7H6B9.1 B7H6B9_BACC4 Glucose-6-phosphate 1-dehydrogenase EC=1.1... 613 e-173 >B1DLK1.1 B1DLK1_9BACL Glucose-6-phosphate 1-dehydrogenase EC=1.1.1.49 Length = 503 Score = 687 bits (1772), Expect = 0.0, Method: Compositional matrix adjust. Identities = 326/487 (66%), Positives = 396/487 (81%), Gaps = 3/487 (0%) Query: 3 MEATTFVLFGATGDLARRKIYPALYNLYLDHKLHHSFSVIGLGRREVADEAFQAMVERSI 62 ME TFVLFGATGDLA+RKIYPALYNL++D KL +FS+IGLGRRE DE FQ+ +E+S+ Sbjct: 1 MEPVTFVLFGATGDLAKRKIYPALYNLFVDGKLPEAFSLIGLGRREWTDEFFQSNIEQSL 60 Query: 63 RDFSRREVNDSASVRGFLKAFRYNVLDVGHTEDYLKLLQRVEQLEADMGGSPNRMFYLSV 122 R FSRRE+ D A ++ F++ FRY VLD+G T+DY KLL +E+ E+ + PNRMFYLSV Sbjct: 61 RQFSRREIQDQALMQSFIRKFRYTVLDIGRTDDYKKLLGIIEERESALQLPPNRMFYLSV 120 Query: 123 GPEFFEPIALNIKESGLGAAKGWKRLVIEKPFGHDLQSAQELNLKLSEAFTEDEIFRIDH 182 GPE+F IA NI ESGLG+ GWKRLVIEKPFGHDLQSA++LN +LS++F E+EIFRIDH Sbjct: 121 GPEYFTTIASNIAESGLGSTAGWKRLVIEKPFGHDLQSARDLNEQLSKSFAEEEIFRIDH 180 Query: 183 YLGKPMVQELDVFQQTNPVLHALWNNRYIANVQITAGETVGVEERAGYYDHVGALRDMFQ 242 YLGKPMVQ L+V + NP++ ALW+NRYIANVQITA ETVGVEERAGYYDHVGA+RDMFQ Sbjct: 181 YLGKPMVQNLEVLESANPIIQALWSNRYIANVQITASETVGVEERAGYYDHVGAVRDMFQ 240 Query: 243 NHMLQLLMMLAIRLPKDSTADEVRFKKKEVMESLEPLEEADVQFNVIRGQYTAGTIQGKP 302 NHMLQ+LMMLAI LP +S+ ++VR KK+VME+L PL +++V NVIRGQYT+G+I G P Sbjct: 241 NHMLQMLMMLAIHLPHNSSPEDVRKHKKQVMEALIPLSKSEVSANVIRGQYTSGSIGGTP 300 Query: 303 VLGYTSEPGIPADSQNDTFIAARLQIDDPFWKGVPFYIRTGKRMKEKSTRIVIEFKEPLK 362 V Y SEPGI A S NDT+IAA+LQ+DD FW+GVPFYIRTGKR+ EKSTRIV+EFKE L Sbjct: 301 VKDYRSEPGIAASSVNDTYIAAKLQVDDYFWRGVPFYIRTGKRLHEKSTRIVVEFKEALH 360 Query: 363 QNSSAAEDDIPNLLVFEISPNEGITLQLKARDPQHKGKFKAMHIDFHTSSIEVPEAYENL 422 Q S+AA PNLL+ EI+PNEGI LQL ++ G+ K + I H SS ++PEAYENL Sbjct: 361 QASTAALGGAPNLLLIEINPNEGIMLQLNTKE---NGELKPVQIQLHESSKDIPEAYENL 417 Query: 423 IYDALHGDPSFFAHWNEVELSWKWVQPILNAFAKNSVPLYHYAAGTFGPAESDQLLAENG 482 IYDAL G+P+FFAHW+EVEL+W WVQPIL+AF +N VPL Y AG+ GPAE+D LLAE+G Sbjct: 418 IYDALVGNPTFFAHWDEVELAWAWVQPILDAFQENLVPLASYEAGSNGPAEADALLAEDG 477 Query: 483 HHWWLDS 489 HWW DS Sbjct: 478 FHWWFDS 484 >B7IPP8.1 B7IPP8_BACC2 Glucose-6-phosphate 1-dehydrogenase EC=1.1.1.49 Length = 494 Score = 617 bits (1590), Expect = e-174, Method: Compositional matrix adjust. Identities = 301/498 (60%), Positives = 369/498 (74%), Gaps = 11/498 (2%) Query: 3 MEATTFVLFGATGDLARRKIYPALYNLYLDHKLHHSFSVIGLGRREVADEAFQAMVERSI 62 ME+ TFVLFGATGDLA+RKIYPALYNLY D KL SVIGLGRREV+ FQ ++ SI Sbjct: 1 MESMTFVLFGATGDLAKRKIYPALYNLYRDQKLPKQISVIGLGRREVSHIDFQKRIKESI 60 Query: 63 RDFSRREVNDSASVRGFLKAFRYNVLDVGHTEDYLKLLQRVEQLEADMGGSPNRMFYLSV 122 FSR+ + + GFL FRY LDV EDY +LLQ V + E ++ NRMFYLSV Sbjct: 61 ETFSRQREEGTPELEGFLDNFRYCPLDVSKPEDYERLLQVVREREEELHIKGNRMFYLSV 120 Query: 123 GPEFFEPIALNIKESGLGAAKGWKRLVIEKPFGHDLQSAQELNLKLSEAFTEDEIFRIDH 182 PEFFE IALNIKESGL GWKRL+IEKPFGHDL SA+ELN KLS F EDEI+RIDH Sbjct: 121 APEFFETIALNIKESGLDKTDGWKRLMIEKPFGHDLTSARELNDKLSRTFEEDEIYRIDH 180 Query: 183 YLGKPMVQELDVFQQTNPVLHALWNNRYIANVQITAGETVGVEERAGYYDHVGALRDMFQ 242 YLGKPM+Q L+ + NPVL ++WN +IANVQITA ETVGVEERAGYYDH GA+RDM Q Sbjct: 181 YLGKPMIQNLEALEFANPVLQSIWNKEHIANVQITASETVGVEERAGYYDHAGAIRDMVQ 240 Query: 243 NHMLQLLMMLAIRLPKDSTADEVRFKKKEVMESLEPLEEADVQFNVIRGQYTAGTIQGKP 302 NHMLQ+LMM A+ LP+ A E+R +K++VME+L +++ DVQ ++IRGQY++G I+G Sbjct: 241 NHMLQILMMTAMNLPEKVNACEIREEKRKVMETLRKVKKEDVQSHIIRGQYSSGEIKGGQ 300 Query: 303 VLGYTSEPGIPADSQNDTFIAARLQIDDPFWKGVPFYIRTGKRMKEKSTRIVIEFKEPLK 362 V+ Y EPG+ S DTF+AARL ID+PFW GVPFYIRTGKRMKEKSTRIVIEFK LK Sbjct: 301 VVAYKEEPGVNPSSNIDTFVAARLWIDNPFWTGVPFYIRTGKRMKEKSTRIVIEFKNTLK 360 Query: 363 Q-----NSSAAEDDIPNLLVFEISPNEGITLQLKARDPQHKGKFKAMHIDFHTSSIE--V 415 Q N +AA PNLL+ EISP E ++LQL +++P G+ + M I+F ++ V Sbjct: 361 QQYQDNNPNAA----PNLLIIEISPGENVSLQLNSKNPLKNGEIEPMRINFTCEQVDVGV 416 Query: 416 PEAYENLIYDALHGDPSFFAHWNEVELSWKWVQPILNAFAKNSVPLYHYAAGTFGPAESD 475 PEAYE LI+DA+ GD +FFAHW EVELSW+WVQPIL AF +N +PL+ Y +G++GP S+ Sbjct: 417 PEAYERLIHDAVSGDATFFAHWREVELSWEWVQPILEAFEENLLPLHEYESGSYGPEASN 476 Query: 476 QLLAENGHHWWLDSAVEE 493 +LL E+G WWLD E+ Sbjct: 477 ELLQESGFKWWLDQETEK 494 >B5ULI3.1 B5ULI3_BACCE Glucose-6-phosphate 1-dehydrogenase EC=1.1.1.49 Length = 494 Score = 615 bits (1586), Expect = e-174, Method: Compositional matrix adjust. Identities = 301/498 (60%), Positives = 368/498 (73%), Gaps = 11/498 (2%) Query: 3 MEATTFVLFGATGDLARRKIYPALYNLYLDHKLHHSFSVIGLGRREVADEAFQAMVERSI 62 ME+ TFVLFGATGDLA+RKIYPALYNLY D KL SVIGLGRR+V+ E FQ ++ SI Sbjct: 1 MESMTFVLFGATGDLAKRKIYPALYNLYRDQKLPKQISVIGLGRRQVSHEDFQERIKESI 60 Query: 63 RDFSRREVNDSASVRGFLKAFRYNVLDVGHTEDYLKLLQRVEQLEADMGGSPNRMFYLSV 122 FSR+ + + GFL FRY LDV EDY +LLQ V + E ++ NRMFYLSV Sbjct: 61 ETFSRQREEGTPELEGFLDNFRYCPLDVSKPEDYERLLQVVREREEELHIKGNRMFYLSV 120 Query: 123 GPEFFEPIALNIKESGLGAAKGWKRLVIEKPFGHDLQSAQELNLKLSEAFTEDEIFRIDH 182 PEFFE IALNIKESGL GWKRL+IEKPFGHDL SA+ELN KLS F EDEI+RIDH Sbjct: 121 APEFFETIALNIKESGLDKTDGWKRLMIEKPFGHDLTSARELNDKLSRTFEEDEIYRIDH 180 Query: 183 YLGKPMVQELDVFQQTNPVLHALWNNRYIANVQITAGETVGVEERAGYYDHVGALRDMFQ 242 YLGKPM+Q L+ + NPVL ++WN +IANVQITA ETVGVEERAGYYD GA+RDM Q Sbjct: 181 YLGKPMIQNLEALEFANPVLQSIWNKEHIANVQITASETVGVEERAGYYDQAGAIRDMVQ 240 Query: 243 NHMLQLLMMLAIRLPKDSTADEVRFKKKEVMESLEPLEEADVQFNVIRGQYTAGTIQGKP 302 NHMLQ+LMM A+ LP+ A E+R +K++VME+L +++ DVQ ++IRGQY AG I+G Sbjct: 241 NHMLQILMMTAMNLPEKVNACEIREEKRKVMETLRKVKKEDVQSHIIRGQYAAGEIKGGQ 300 Query: 303 VLGYTSEPGIPADSQNDTFIAARLQIDDPFWKGVPFYIRTGKRMKEKSTRIVIEFKEPLK 362 V+ Y EPG+ S DTF+AARL ID+PFW GVPFYIRTGKRMKEKSTRIVIEFK LK Sbjct: 301 VVAYKEEPGVNPSSNIDTFVAARLWIDNPFWTGVPFYIRTGKRMKEKSTRIVIEFKNTLK 360 Query: 363 Q-----NSSAAEDDIPNLLVFEISPNEGITLQLKARDPQHKGKFKAMHIDFHT--SSIEV 415 Q N +AA PNLL+ EISP E ++LQL +++P G+ + M I+F + + V Sbjct: 361 QQYQDNNPNAA----PNLLIIEISPGENVSLQLNSKNPLKNGEIEPMRINFTCEQADVGV 416 Query: 416 PEAYENLIYDALHGDPSFFAHWNEVELSWKWVQPILNAFAKNSVPLYHYAAGTFGPAESD 475 PEAYE LI+DA+ GD +FFAHW EVELSW+WVQPIL AF +N +PL+ Y +G++GP S+ Sbjct: 417 PEAYERLIHDAVSGDATFFAHWREVELSWEWVQPILEAFEENLLPLHEYESGSYGPEASN 476 Query: 476 QLLAENGHHWWLDSAVEE 493 +LL E+G WWLD E+ Sbjct: 477 ELLQESGFKWWLDQETEK 494 >Q3EVW4.1 Q3EVW4_BACTI Glucose-6-phosphate 1-dehydrogenase EC=1.1.1.49 Length = 511 Score = 615 bits (1585), Expect = e-174, Method: Compositional matrix adjust. Identities = 300/500 (60%), Positives = 370/500 (74%), Gaps = 11/500 (2%) Query: 1 MEMEATTFVLFGATGDLARRKIYPALYNLYLDHKLHHSFSVIGLGRREVADEAFQAMVER 60 + +E+ TFVLFGATGDLA+RKIYPALYNLY D KL SVIGLGRREV+ FQ ++ Sbjct: 16 LNLESMTFVLFGATGDLAKRKIYPALYNLYRDQKLPKQISVIGLGRREVSHIDFQKRIKE 75 Query: 61 SIRDFSRREVNDSASVRGFLKAFRYNVLDVGHTEDYLKLLQRVEQLEADMGGSPNRMFYL 120 SI FSR+ + + GFL FRY LDV EDY +LLQ V + E ++ NRMFYL Sbjct: 76 SIETFSRQREEGTPELEGFLDNFRYCPLDVSKPEDYERLLQVVREREEELHIKGNRMFYL 135 Query: 121 SVGPEFFEPIALNIKESGLGAAKGWKRLVIEKPFGHDLQSAQELNLKLSEAFTEDEIFRI 180 SV PEFFE IALNIKESGL GWKRL+IEKPFGHDL SA+ELN KLS F EDEI+RI Sbjct: 136 SVAPEFFETIALNIKESGLDKTDGWKRLMIEKPFGHDLTSARELNDKLSRTFEEDEIYRI 195 Query: 181 DHYLGKPMVQELDVFQQTNPVLHALWNNRYIANVQITAGETVGVEERAGYYDHVGALRDM 240 DHYLGKPM+Q L+ + NPVL ++WN +IANVQITA ETVGVEERAGYYDH GA+RDM Sbjct: 196 DHYLGKPMIQNLEALEFANPVLQSIWNKEHIANVQITASETVGVEERAGYYDHAGAIRDM 255 Query: 241 FQNHMLQLLMMLAIRLPKDSTADEVRFKKKEVMESLEPLEEADVQFNVIRGQYTAGTIQG 300 QNHMLQ+LMM A+ LP+ A E+R +K++VME+L +++ DVQ ++IRGQY++G I+G Sbjct: 256 VQNHMLQILMMTAMNLPEKVNACEIREEKRKVMETLRKVKKEDVQSHIIRGQYSSGEIKG 315 Query: 301 KPVLGYTSEPGIPADSQNDTFIAARLQIDDPFWKGVPFYIRTGKRMKEKSTRIVIEFKEP 360 V+ Y EPG+ S DTF+AARL ID+PFW GVPFYIRTGKRMKEKSTRIVIEFK Sbjct: 316 GQVVAYKEEPGVNPSSNIDTFVAARLWIDNPFWTGVPFYIRTGKRMKEKSTRIVIEFKNT 375 Query: 361 LKQ-----NSSAAEDDIPNLLVFEISPNEGITLQLKARDPQHKGKFKAMHIDFHTSSIE- 414 LKQ N +AA PNLL+ EISP E ++LQL +++P G+ + M I+F ++ Sbjct: 376 LKQQYQDNNPNAA----PNLLIIEISPGENVSLQLNSKNPLKNGEIEPMRINFTCEQVDV 431 Query: 415 -VPEAYENLIYDALHGDPSFFAHWNEVELSWKWVQPILNAFAKNSVPLYHYAAGTFGPAE 473 VPEAYE LI+DA+ GD +FFAHW EVELSW+WVQPIL AF +N +PL+ Y +G++GP Sbjct: 432 GVPEAYERLIHDAVSGDATFFAHWREVELSWEWVQPILEAFEENLLPLHEYESGSYGPEA 491 Query: 474 SDQLLAENGHHWWLDSAVEE 493 S++LL E+G WWLD E+ Sbjct: 492 SNELLQESGFKWWLDQETEK 511 >B7H6B9.1 B7H6B9_BACC4 Glucose-6-phosphate 1-dehydrogenase EC=1.1.1.49 Length = 494 Score = 613 bits (1581), Expect = e-173, Method: Compositional matrix adjust. Identities = 298/494 (60%), Positives = 365/494 (73%), Gaps = 3/494 (0%) Query: 3 MEATTFVLFGATGDLARRKIYPALYNLYLDHKLHHSFSVIGLGRREVADEAFQAMVERSI 62 ME+ TFVLFGATGDLA+RKIYPALYNLY D KL SVIGLGRREV+ FQ ++ SI Sbjct: 1 MESMTFVLFGATGDLAKRKIYPALYNLYRDQKLPKQISVIGLGRREVSHVDFQKRIKESI 60 Query: 63 RDFSRREVNDSASVRGFLKAFRYNVLDVGHTEDYLKLLQRVEQLEADMGGSPNRMFYLSV 122 FSR ++ + GFL FRY LDV EDY +LLQ V + E ++ NRMFYLSV Sbjct: 61 ETFSRHREEGTSDLEGFLDNFRYCPLDVSKPEDYERLLQVVREREEELHIKGNRMFYLSV 120 Query: 123 GPEFFEPIALNIKESGLGAAKGWKRLVIEKPFGHDLQSAQELNLKLSEAFTEDEIFRIDH 182 PEFFE IALNIKESGL GWKRL+IEKPFGHDL SA+ELN KLS F EDEI+RIDH Sbjct: 121 APEFFETIALNIKESGLDKTDGWKRLMIEKPFGHDLTSARELNDKLSRTFEEDEIYRIDH 180 Query: 183 YLGKPMVQELDVFQQTNPVLHALWNNRYIANVQITAGETVGVEERAGYYDHVGALRDMFQ 242 YLGKPM+Q L+ + NPVL ++WN +IANVQITA ETVGVEERAGYYD GA+RDM Q Sbjct: 181 YLGKPMIQNLEALEFANPVLQSIWNKEHIANVQITASETVGVEERAGYYDQAGAIRDMVQ 240 Query: 243 NHMLQLLMMLAIRLPKDSTADEVRFKKKEVMESLEPLEEADVQFNVIRGQYTAGTIQGKP 302 NHMLQ+LMM A+ LP+ A E+R +K++VME+L +++ DVQ ++IRGQY AG I+G Sbjct: 241 NHMLQILMMTAMNLPEKVNACEIREEKRKVMETLRKVKKEDVQSHIIRGQYAAGEIKGGQ 300 Query: 303 VLGYTSEPGIPADSQNDTFIAARLQIDDPFWKGVPFYIRTGKRMKEKSTRIVIEFKEPLK 362 V+ Y EPG+ S DTF+AARL ID+PFW GVPFYIRTGKRMKEKSTRIVIEFK LK Sbjct: 301 VVAYKEEPGVNPSSNIDTFVAARLWIDNPFWTGVPFYIRTGKRMKEKSTRIVIEFKNTLK 360 Query: 363 QN-SSAAEDDIPNLLVFEISPNEGITLQLKARDPQHKGKFKAMHIDFHT--SSIEVPEAY 419 Q + + PNLL+ EISP E ++LQL +++P G+ + M I+F + + VPEAY Sbjct: 361 QQYQDSNPNAAPNLLIIEISPGENVSLQLNSKNPLKNGEIEPMRINFTCEQADVGVPEAY 420 Query: 420 ENLIYDALHGDPSFFAHWNEVELSWKWVQPILNAFAKNSVPLYHYAAGTFGPAESDQLLA 479 E LI+DA+ GD +FFAHW EVELSW+WVQPIL AF +N +PL+ Y +G++GP S++LL Sbjct: 421 ERLIHDAVSGDATFFAHWKEVELSWEWVQPILEAFEENLLPLHEYESGSYGPDASNELLQ 480 Query: 480 ENGHHWWLDSAVEE 493 E+G WWLD E+ Sbjct: 481 ESGFKWWLDQETEK 494 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,064,630,854 Number of extensions: 133703032 Number of successful extensions: 294398 Number of sequences better than 1.0e-05: 2163 Number of HSP's gapped: 287197 Number of HSP's successfully gapped: 2167 Length of query: 505 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 365 Effective length of database: 1,741,754,103 Effective search space: 635740247595 Effective search space used: 635740247595 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 133 (55.8 bits)