BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0341.0037.p (594 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K3I7.1 B3K3I7_9BACI Histidine kinase internal region 350 3e-94 B1DBG2.1 B1DBG2_9BACL Histidine kinase internal region 237 2e-60 A7VQP4.1 A7VQP4_9CLOT Putative uncharacterized protein 208 1e-51 C0C1J1.1 C0C1J1_9CLOT Putative uncharacterized protein 206 4e-51 B1DIU3.1 B1DIU3_9BACL Multi-sensor signal transduction histidine... 196 8e-48 >B3K3I7.1 B3K3I7_9BACI Histidine kinase internal region Length = 610 Score = 350 bits (897), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 214/578 (37%), Positives = 313/578 (54%), Gaps = 36/578 (6%) Query: 30 GAISYKKYTAGVERSTVELSYQVVNQININLEHYIKELDRLTLMPLYDEDVMHILQSHSG 89 G +Y ++ VER T + + Q+V+QIN NL+ + E+ RLTLMPLYD V+ IL+ + Sbjct: 33 GVATYVGFSNSVERRTSDYTAQLVDQINRNLDRTLMEMQRLTLMPLYDSGVLSILRKYRE 92 Query: 90 SGSASTYLTTDETLKMNLFISSLAFDRGEIESILVFTNDGGIFSNLDQSVRKRW-DRSMA 148 S T +E KM L+I+S+ FDR EI+SI +F G FS+L S + D Sbjct: 93 EDSLHQQPTVEERSKMQLYIASMTFDRPEIDSIQIFAGSGYTFSSLAPSAIAAYTDVERQ 152 Query: 149 EWMGSVKQEDGGLAIIPPHNAAYYTEPKQGIISVARVIREPYTNKMLGIVKVDLTPQGFG 208 W V + G ++PPH +YY + Q SVAR+IREP TN+ LG+VK+DL F Sbjct: 153 PWYPGVVEARGAWVLLPPHRPSYYLDGNQSYFSVARLIREPNTNRTLGLVKIDLKQTLFK 212 Query: 209 SILSTVRLGGSGLLQITGKDQVMLYSAAA---------------GLPDSSES-------- 245 ++ VRL +G + + + + Y+A A GL SE+ Sbjct: 213 QLVDNVRLEENGGIVVQNSREELFYTATADGDTEASKLLSDRILGLSGRSETASEILHME 272 Query: 246 ---YITASAQSAYTGLKVTSLIPRTQLREDARELTNSTLIVSXXXXXXXXXXXXXXSNRL 302 Y+ S S Y+ + + S IP L + +EL N TL+ S RL Sbjct: 273 GSKYLVVSNYSRYSDINIVSYIPVASLLVETKELRNFTLLAGLICLVLAGALAIYFSYRL 332 Query: 303 IKPIAHLQSKMRQVKRGLFRERATVTTNDEIGQLTEGFNTMIGEIDRLVKEVYXXXXXXX 362 +P+ L KMR V+ G F++ VT DEIG+L GFN M+ EIDRLV EVY Sbjct: 333 TQPLGTLVRKMRLVELGDFKQSVPVT-EDEIGRLGSGFNRMVEEIDRLVHEVYVLGMRER 391 Query: 363 XXXXXXXQSQIHPHFLYNTLEMVNMLALQGSTRELSGVVTSLGKLLRYTVGRQDPMVYVL 422 QSQI PHF+YNTLE ++MLA Q + ++S + T+LG+L+R V + ++ + Sbjct: 392 EAELAALQSQIQPHFIYNTLESISMLARQRNNEDVSEMATALGRLIRSAVEQDRSLIRLG 451 Query: 423 DEVKFVEAYLKIQGMRLGDKLQAVIHMDSSFDYCLVPKLILQPLIENVIEHAMGP----D 478 +E++ E+Y++IQ MR G +LQA+ ++ D CLVPKL+LQPLIEN I H +G Sbjct: 452 EELETAESYIRIQKMRHGSRLQAMFDIEEGLDDCLVPKLLLQPLIENAIMHGIGDREQGG 511 Query: 479 TVHLALTAAVQEDDLILSVKDDGIGISGERMKELEEQLYRDKSRSVPESEPGGFGRIRKG 538 TV+ +T A ED+++L+V+DDG G+S + + L+ L + V P R G Sbjct: 512 TVY--VTVARFEDEVLLTVRDDGRGLSEDELAALQASL-EEAGDDVAAKTPAMPLR-GHG 567 Query: 539 FALRNVHQRLRLLYGEPYGLYIDNTAERGVTISLRLPM 576 AL+N++QRLRL+YG ID + +G ++ LP Sbjct: 568 VALKNINQRLRLIYGRDCDFEIDGSLGQGTAFTVTLPF 605 >B1DBG2.1 B1DBG2_9BACL Histidine kinase internal region Length = 595 Score = 237 bits (605), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 167/592 (28%), Positives = 287/592 (48%), Gaps = 35/592 (5%) Query: 8 VPLRTKFIVLFCLLITVPFLVIGAISYKKYTAGVERSTVELSYQVVNQININLEHYIKEL 67 + L K I++ LLI VP VIGA S+ + + +E + Q++ Q+ +N++ Y+ EL Sbjct: 14 LALARKLILVNVLLIVVPLGVIGAWSFSIFASKMEEQVGKYQLQMLKQVTLNIDTYMNEL 73 Query: 68 DRLTLMPLYDEDVMHILQSHSGSGSASTYLTTDETLKMNLFISSLAFD-RGEIESILVFT 126 +RL+LMP ++++ L + G A L+ E +N F+S + + R +I I +F Sbjct: 74 NRLSLMPYQYQEILDFLATSRKPGEA---LSLQEIDDLNNFVSKVFLNGRVDIMGISLFG 130 Query: 127 NDGGIFSNLDQS--VRKRWDRSMAEWMGSVKQEDGGLAIIPPHNAAYYTEPKQGIISVAR 184 G + L +S + EW+ K G I H + + S+AR Sbjct: 131 EHGASYVVLPESQYMTTYQLGGNTEWLEKAKGRFGQPTFITTHEVKSTSGTAYQVFSIAR 190 Query: 185 VIREPYTNKMLGIVKVDLTPQGFGSILSTVRLGGSGLLQITG--------KDQVMLYSAA 236 +R + LG + +D+ P +LS V LG L +T K++ +Y Sbjct: 191 ELRSFDSGDTLGYIVIDIDPAEVRKLLSQVSLGSKESLYMTDSAGDLVLRKEKTAIYPVI 250 Query: 237 AGLPD--------SSESYITASAQSAYTGLKVTSLIPRTQLREDARELTNSTLIVSXXXX 288 GL D +S + A S TG ++P + L +D+ + NS +++ Sbjct: 251 EGLSDEGVSHHKIDGKSLLVAHVSSEVTGWTTVGVVPVSVLMKDSLVVRNSIILIGGICV 310 Query: 289 XXXXXXXXXXSNRLIKPIAHLQSKMRQVKRGLFRERATVTTNDEIGQLTEGFNTMIGEID 348 + R+ P+ L+S MR+V+RG + V DE+GQL FN M+ + Sbjct: 311 GLAVLLSVFIAFRITSPLRMLRSLMRKVERGDLKVSFPVRQWDEVGQLGNAFNMMVSHLS 370 Query: 349 RLVKEVYXXXXXXXXXXXXXXQSQIHPHFLYNTLEMVNMLALQGSTRELSGVVTSLGKLL 408 L +Y QS+I+PHFLYNTL ++M A RE+ + +L +LL Sbjct: 371 ELGYRLYETEIREKDAEIAALQSKINPHFLYNTLGSISMYAEVEGNREVVTMTNNLSRLL 430 Query: 409 RYTVGRQDPMVYVLDEVKFVEAYLKIQGMRLGDKLQAVIHMDSSFDYCLVPKLILQPLIE 468 RY++ + V + DE+ V+ Y+ IQ MR D++ + +D S C V L++QP++E Sbjct: 431 RYSLSGRKETVTLRDELDHVKGYMTIQKMRYDDRIDFRLEVDESLYGCPVIPLMIQPIVE 490 Query: 469 NVIEHAM--GPDTVHLALTAAVQEDDLILSVKDDGIGISGERMKELEEQLYRDKSRSVPE 526 N I H + G + L+ ++ L++ ++DDGIG++ E++ + +++ DK + Sbjct: 491 NAINHGLDKGIGEGRIQLSCYQEQGMLMIVIEDDGIGMTSEQLSAMRKRM--DKIHDL-- 546 Query: 527 SEPGGFGRIRKGFALRNVHQRLRLLYGEPYGLYIDNTAERGVTISLRLPMHW 578 GG G L NVH+R+RL YGE YGL +++ +G+ + L +P+ + Sbjct: 547 ---GG----TSGNGLMNVHRRIRLHYGEQYGLQLESMPFQGLKVILTMPIAY 591 >A7VQP4.1 A7VQP4_9CLOT Putative uncharacterized protein Length = 634 Score = 208 bits (530), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 156/600 (26%), Positives = 268/600 (44%), Gaps = 47/600 (7%) Query: 10 LRTKFIVLFCLLITVPFLVIGAISYKKYTAGVERSTVELSYQVVNQININLEHYIKELDR 69 +R + LLI + + +SY +YT + + E Q + Q++INL Y+ EL R Sbjct: 35 IRFSLTSVVALLILLSVFISSTLSYSRYTRDFQEQSSEQIDQTLEQLSINLSTYLDELFR 94 Query: 70 LTLMPLYDEDVMHILQSHSGSGSASTYLTTDETLKMNLFISS-----LAFDRGEIESILV 124 LT+ YD+ V+ L++ GS + L+ I S + R +I ++ V Sbjct: 95 LTVYLYYDDSVVAALEATGGSDI--------DRLQRRRVIESYLDKIMIMPRKDILNVFV 146 Query: 125 FTNDGGIFSNLDQSVRKRWDRSMAEWMGSVKQEDGGLAIIPPHNAAYYTEPKQGIISVAR 184 T+D + +SV D +W + +PPH + PK + S+ + Sbjct: 147 ITDDIYFSGRMPKSVNHSADYQALDWYQDAMSTQSPI-FVPPHTEQLVSYPKDTVFSIVK 205 Query: 185 VIREPYT-NKMLGIVKVDLTPQGFGSILSTVRLGGSGLLQITGKDQVMLYSAAA------ 237 ++ ++++G++KVD + G I V +G G + I D+ ++Y++A+ Sbjct: 206 QLKSVQNIDQVIGVIKVDASYSGIADIARKVNMGEQGGVFIIDNDKNLIYNSASQEQVEL 265 Query: 238 ----GLPDS--------SESYITASAQSAYTGLKVTSLIPRTQLREDARELTNSTLIVSX 285 L S S Y+ + Q + ++ +L ++A++ + T +++ Sbjct: 266 LSGVALASSGSWIEKIGSAEYMVNTVQVKSADWTIVAVNSLDELTKNAQKTRDFTFLLAT 325 Query: 286 XXXXXXXXXXXXXSNRLIKPIAHLQSKMRQVKRGLFRERATVTTNDEIGQLTEGFNTMIG 345 ++ +KP+ + M++V++G F+ + NDEIG L + FN M+ Sbjct: 326 LSSLSAILVLLIFTHSFLKPLMGIVQLMKEVRKGNFQVSFSSKRNDEIGYLGDSFNAMVK 385 Query: 346 EID-------RLVKEVYXXXXXXXXXXXXXXQSQIHPHFLYNTLEMVNMLALQGSTRELS 398 I+ L K+VY QSQI PHFLYNTL M++M G + Sbjct: 386 TINDNIEKNTELAKKVYEAEMLHTEAQLHALQSQIKPHFLYNTLNMISMQIQVGRLEQAV 445 Query: 399 GVVTSLGKLLRYTVGRQDPMVYVLDEVKFVEAYLKIQGMRLGDKLQAVIHMDSSFDYCLV 458 + L +LLR + + D V V DE ++AYL IQ R +L + +D S + Sbjct: 446 DNIEKLHRLLR-GMAKWDREVLVEDEFAILDAYLGIQSSRFEQRLSYELKLDDSLKKQYI 504 Query: 459 PKLILQPLIENVIEHAMGPDTVHLALTAA--VQEDDLILSVKDDGIGISGERMKELEEQL 516 ILQPL+EN + H +T ++E V DDG G++ E++K L E+L Sbjct: 505 LAFILQPLVENAVIHGCETQRRRTKITVEGFLKEGRCYFVVSDDGKGMTEEQLKALREKL 564 Query: 517 YRDKSRSVPESEPGGFGRIRKGFALRNVHQRLRLLYGEPYGLYIDNTAERGVTISLRLPM 576 R PG G I L NV++R+++ YG YG+ I + + G T + LP+ Sbjct: 565 GRTAENENQSVSPGADGHI----GLENVNKRIQIHYGSCYGIRISSQPDAGTTCRVELPL 620 >C0C1J1.1 C0C1J1_9CLOT Putative uncharacterized protein Length = 601 Score = 206 bits (525), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 150/603 (24%), Positives = 280/603 (46%), Gaps = 46/603 (7%) Query: 8 VPLRTKFIVLFCLLITVPFLVIGAISYKKYTAGVERSTVELSYQVVNQININLEHYIKEL 67 + ++ K + F L+I V ++G S + ++ + +NQ+ N+E I+++ Sbjct: 9 LKMKNKLFIGFILVIAVLVSLLGYFSMTFSEQSIRTQMLDSIQETMNQMGENIEGEIQKV 68 Query: 68 DRLTLMPLYDEDVMHILQSHSGSGSASTYLTTDETLKMNLFISSLAFDRGEIESILVFTN 127 ++ +E++ +LQ G+ Y + D+T++ L S A+ +E + V + Sbjct: 69 LDVSAQVCLNEELCTVLQEEK-PGTIEEYYSKDKTMRQILNESYAAY--FSVEDVFVCSY 125 Query: 128 DGGIFSNLDQ--SVRKRWDRSMAEWMGSVKQEDGGLAIIPPHNAAYYT---EPKQGIISV 182 +G ++ + S+ +D + W +KQ G++I+ ++++ Y EP Q + S+ Sbjct: 126 NGSVYGSDKNKLSLTADYDFTRTGWFADMKQSGAGVSILSQYDSSSYISTGEP-QKLFSI 184 Query: 183 ARVIREPYTNKMLGIVKVDLTPQGFGSILSTVRLGGSGLLQITGKDQVMLYSAAAGLPDS 242 + I + K +G + V + G++L +V I ++ ++Y PDS Sbjct: 185 VKKIYNYRSGKEIGCLIVHMNSDILGNVLQSVNSNEYQQCLIIDNNKKIIYH-----PDS 239 Query: 243 --------------------------SESYITASAQSAYTGLKVTSLIPRTQLREDAREL 276 SE + SA TG V S++ + + L Sbjct: 240 DYIGTQYREARVSELLTMENGYMESLSEKGYLVFSTSAVTGWSVISVVDNKYIMDSINRL 299 Query: 277 TNSTLIVSXXXXXXXXXXXXXXSNRLIKPIAHLQSKMRQVKRGLFRERATVTTNDEIGQL 336 ++ + S + P+A LQ KM QV G F RA +DEIGQL Sbjct: 300 RLFLILTAVFCVVLSVYFASYISKTISDPVARLQRKMYQVGEGDFDIRAATGASDEIGQL 359 Query: 337 TEGFNTMIGEIDRLVKEVYXXXXXXXXXXXXXXQSQIHPHFLYNTLEMVNMLALQGSTRE 396 T F+ M+ +L++ VY Q+QI+PHFLYNTL+ ++M+A + E Sbjct: 360 TLSFDKMVERTKQLIENVYQSEIYQKEAELNALQAQINPHFLYNTLQTIDMMAEEEGADE 419 Query: 397 LSGVVTSLGKLLRYTVGRQDPMVYVLDEVKFVEAYLKIQGMRLGDKLQAVIHMDSSFDYC 456 +S +L K+ RY++ R V+V DE+ +E Y+ IQ +R G KL+ + + Sbjct: 420 ISDACQALSKIFRYSINRGQEFVHVQDEIVHIENYMLIQKLRFGGKLEVRYDIQNECREL 479 Query: 457 LVPKLILQPLIENVIEHAMGP--DTVHLALTAAVQEDDLILSVKDDGIGISGERMKELEE 514 + KL++QP++EN + H M D ++ + +ED L V+D+G GI+ ++ EL E Sbjct: 480 YIVKLLIQPMVENAVVHGMENVLDKCYVTIRVYRKEDCLYAEVEDNGTGIAPGQLMELNE 539 Query: 515 QLYRD-KSRSVPESEPGGFGRIRKGFALRNVHQRLRLLYGEPYGLYIDNTAERGVTISLR 573 +L R + + V E + + + + L N + R++L +G+ YG+ I + G + ++ Sbjct: 540 KLARSAEQKMVHEVD---YVKNHRSIGLENTNARIKLYFGQEYGITITSEEGTGTKVCIK 596 Query: 574 LPM 576 LP+ Sbjct: 597 LPV 599 >B1DIU3.1 B1DIU3_9BACL Multi-sensor signal transduction histidine kinase Length = 586 Score = 196 bits (497), Expect = 8e-48, Method: Compositional matrix adjust. Identities = 159/589 (26%), Positives = 268/589 (45%), Gaps = 61/589 (10%) Query: 15 IVLFCLLITVPFLVIGAISYKKYTAGVERSTVELSYQVVNQININLEHYIKELDRLTLMP 74 ++LF + I V V+ + Y ++ A E + S Q+V+Q++ +LE+ ++ L M Sbjct: 17 LILFSVFIIV---VVSTVLYSRFAATAEENAFRNSQQIVDQVSYSLENNVQATSDLFNM- 72 Query: 75 LYDEDVMHILQSHSGSGSASTYLTTDETLKMNLFISSLAFDRGEIESILVFTNDGGIFSN 134 M+ + SG E+L L +++ R + S+ +F + G + + Sbjct: 73 ------MYHTITQSGD-------VDSESLHRQL--ATMMSTRADTVSLALFDDKGQLVMD 117 Query: 135 L-DQSVRKRWDRSMAEWMGSVKQEDGGLAIIPPHNAAYYTEPKQGIISVARVIREPYTNK 193 L D +++ D + W S L+I PH Y E + ++S+++ I + K Sbjct: 118 LPDVTMKNALDVTSESWFQSALDTPSHLSISLPHVQNLYKEQFRWVVSLSKSITMIHNGK 177 Query: 194 -MLGIVKVDLTPQGFGSILSTVRLGGSGLLQITGKD--------QVMLYSAAA------- 237 + G++ +D+ + V LG G + I + Q+ L A Sbjct: 178 PIQGVLLLDVNFNTIDELSDRVSLGEKGYVYILDESAGNIVYHPQLQLIYAGLKNENVEL 237 Query: 238 GLPDSSESYI--TASAQSAYT-------GLKVTSLIPRTQLREDARELTNSTLIVSXXXX 288 L + SYI T+SA + G KV + R + EL S + Sbjct: 238 ALKHTYGSYIDKTSSATKIISVQTIGNVGWKVVGVSYRDEAMTSISELNRSMFQLLLALI 297 Query: 289 XXXXXXXXXXSNRLIKPIAHLQSKMRQVKRGLFRERATVTTNDEIGQLTEGFNTMIGEID 348 S R+ KPI L+ M+ V+ G F + A E+ QL + FN MI I Sbjct: 298 LIVVLLSSIVSRRISKPIKQLELSMKNVEHGNFEQTAIGEGPLEVRQLADRFNIMISTIK 357 Query: 349 RLVKEVYXXXXXXXXXXXXXXQSQIHPHFLYNTLEMVNMLALQGSTRELSGVVTSLGKLL 408 +L++++ Q+QI+PHFLYNTL V + E++ ++TSL KL Sbjct: 358 KLMRQIVTEQESKRTYELEALQAQINPHFLYNTLNSVVRMVGMNKNEEVTTMITSLSKLF 417 Query: 409 RYTVGRQDPMVYVLDEVKFVEAYLKIQGMRLGDKLQAVIHMDSSFDYCLVPKLILQPLIE 468 R ++G+ ++ + DE++ YL IQ MR +K I D KLI+QPLIE Sbjct: 418 RISLGKGKSIITIADELEHARNYLVIQQMRFKNKFDFSIKADGEVLNYATLKLIVQPLIE 477 Query: 469 NVIEHAMGP--DTVHLALTAAVQEDDLILSVKDDGIGISGERMKELEEQLYRDKSRSVPE 526 N + H + P D H+ + A V DD+++ V+D+G+G+S ER+K++ + V Sbjct: 478 NALVHGIEPSVDKGHIWVEAKVDCDDIVIEVRDNGLGMSEERLKQV-------TAGQVTS 530 Query: 527 SEPGGFGRIRKGFALRNVHQRLRLLYGEPYGLYIDNTAERGVTISLRLP 575 S+ G G + NV +R+RL YG+ YGL+ + E G T+++R P Sbjct: 531 SKGSGVG-------VMNVQERIRLFYGQAYGLHFASELEEGTTVTIRFP 572 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.136 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,189,320,076 Number of extensions: 130507984 Number of successful extensions: 359667 Number of sequences better than 1.0e-05: 2096 Number of HSP's gapped: 356136 Number of HSP's successfully gapped: 2103 Length of query: 594 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 452 Effective length of database: 1,722,912,073 Effective search space: 778756256996 Effective search space used: 778756256996 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 134 (56.2 bits)