BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0341.0026.p (548 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1D9L1.1 B1D9L1_9BACL Two component transcriptional regulator, A... 712 0.0 B3KF78.1 B3KF78_9BACI Response regulator receiver 196 4e-48 B1D5Y1.1 B1D5Y1_9BACL Two component transcriptional regulator, A... 196 7e-48 B1D907.1 B1D907_9BACL Two component transcriptional regulator, A... 183 4e-44 B3K421.1 B3K421_9BACI Response regulator receiver 172 7e-41 >B1D9L1.1 B1D9L1_9BACL Two component transcriptional regulator, AraC family Length = 544 Score = 712 bits (1839), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/546 (63%), Positives = 434/546 (79%), Gaps = 2/546 (0%) Query: 1 MYKVLIIDDEEPLREAIHILGDWKGLGVDQVLEATDGRVGLEMLRKHKIDLALVDMKMPE 60 MYKVLIIDDEEPLREAI ILGDWKGLGV +VLEATDG++GLEM+ H +DL +VDMKMP Sbjct: 1 MYKVLIIDDEEPLREAIRILGDWKGLGVAEVLEATDGKMGLEMIANHSVDLVMVDMKMPG 60 Query: 61 LNGSQLLQIAEREFPDLLLIVISGYNDFEYTRQAIRSKVVDYLLKPVNRSDLNSALRKAM 120 ++G++LLQ+ ER++PD+ IVISGYNDFEYTRQAIRSKVVDYLLKP+NR DLN+ALRKA+ Sbjct: 61 MSGAELLQVLERDYPDMPAIVISGYNDFEYTRQAIRSKVVDYLLKPINRPDLNAALRKAV 120 Query: 121 DVLEAKRKRESEFITRNITLNMSLPKLKEKMYLSIIERSFKNQSNEAFLPLIGADKPGNH 180 D+LEA+R RESEFI RNITLNMSLPKLKEKMYLSII+RSF++Q+NEAFLPLIGAD P N Sbjct: 121 DLLEARRVRESEFINRNITLNMSLPKLKEKMYLSIIDRSFRSQTNEAFLPLIGADDPDNR 180 Query: 181 FAVGVLRMLNVEQVRHARFHEDRDLLHFAVTNVINENSGGHFEAFSFASPRSEREFIAIF 240 FA VLRMLN+E+VR ARFH D DLLHFAV N++NE +G +F+AFSFASP+ +RE I I Sbjct: 181 FAAVVLRMLNMEKVRKARFHSDVDLLHFAVGNMLNEIAGEYFQAFSFASPKMDRELIVIL 240 Query: 241 TLKGSYGEDAAFLSLHHMKKTVSTLKELFGILCAGGLGQPYSEVMGIAQSYELAKAALDG 300 T+KG+Y ED A+ SLH M K ++ L++L GI+ A G+G P +M IA SYE AKAA++G Sbjct: 241 TMKGAYQEDIAYRSLHQMNKALAALQDLLGIVAAAGIGTPCESIMEIASSYETAKAAING 300 Query: 301 TDLLTLKGSTVSNSGYTKSAAKDSPSLTGRMPLIRSSLESGNAGHAKSILSDFTRKWKSS 360 DLL LKG V+N+ KSA + P +TGRM + R++LESGN AKSILS+ RKW + Sbjct: 301 IDLLKLKGYFVANA-VAKSANEGYP-VTGRMQMFRAALESGNTAGAKSILSEELRKWGGA 358 Query: 361 EHFSLGEADRIIQEFIILLGDIAVELDAVPERLRSGKSKGLRGLGISSDFASFGEFEAVL 420 + F+LG+AD+ + FIIL+ DI++EL E+L + +R +G+S D+AS+ +F +L Sbjct: 359 DLFTLGDADQSLGRFIILMNDISLELGVPREKLPLMEEHPVRFMGLSDDYASYEQFSKLL 418 Query: 421 SSILDVYAGEISRSLAGDRSSVLENIKAYIDNHYFENIKISMFTDKYFLSREYLMKLFKG 480 L Y ++ + + +R + +IKAYIDN Y+E+IKISMF DKYFLSREY+MKLFK Sbjct: 419 EDALHFYLEQLRLTQSANRPFEIGDIKAYIDNRYYEDIKISMFADKYFLSREYIMKLFKQ 478 Query: 481 QYGYGIHEYVQKVRMDKAKELLSDPALKIQDISERLGYKDKNYFSKAFRNYYDCSPSEFR 540 Q+G GIHEYVQ++RMDKAKELL DP+LKIQDISE LGYKDKNYFSKAFRNY+ SP+E+R Sbjct: 479 QFGCGIHEYVQRIRMDKAKELLDDPSLKIQDISEMLGYKDKNYFSKAFRNYFSISPTEYR 538 Query: 541 LLLTEG 546 EG Sbjct: 539 TARKEG 544 >B3KF78.1 B3KF78_9BACI Response regulator receiver Length = 546 Score = 196 bits (499), Expect = 4e-48, Method: Compositional matrix adjust. Identities = 152/565 (26%), Positives = 264/565 (46%), Gaps = 48/565 (8%) Query: 1 MYKVLIIDDEEPLREAIHILGDWKGLGVDQVLEATDGRVGLEMLRKHKIDLALVDMKMPE 60 MY++LI+DDE +R + DW G++ EA DG V LEM+ + + DL L D++MP Sbjct: 1 MYRLLIVDDEPAVRAGLRAYFDWAAYGIEVAGEADDGDVALEMIARDQPDLILTDVRMPN 60 Query: 61 LNGSQLLQIAEREFPDLLLIVISGYNDFEYTRQAIRSKVVDYLLKPVNRSDLNSALRKAM 120 ++G + Q E+P + +I +SG++D +Y + A++ VDY+ KPVN +L++ +++ + Sbjct: 61 MDGITMSQCISSEYPAMKIIFVSGHDDADYLKSAMKVSAVDYIFKPVNLQELSTVIKRVV 120 Query: 121 DVLEAKRKRESEFITRN---ITLNMSLPKLKEKMYLSIIERSFKNQSNEAFLPLIGADKP 177 L+A+ SE I + + L +P L+EK LS+I + +G D P Sbjct: 121 ADLDAE---SSERIYKQELLVKLKEGMPLLREKFLLSMIREGAPKSELAERVSFLGLDLP 177 Query: 178 GN-HFAVGVLRMLNVEQVRHARFHEDRDLLHFAVTNVINENSGGHFEAFSFASPRSEREF 236 N + V V+ + ++ V +R DR LL ++V N+ E H ++F + EF Sbjct: 178 VNASYWVMVVCVDDLADVMASRSERDRQLLWYSVLNIYEELLDAHLRGYAFE--QRTGEF 235 Query: 237 IAIFTLKGSYGEDAAFLSLHHMKKT---VSTLKELFGILCAGGLGQPYSEVMGIAQSYEL 293 + + + G+ + + S L+ I G+ + G+A +Y+ Sbjct: 236 VGVLKVSEPGGDSVSEAAEALFALAGDLRSNLERWLKIGVTIGISDMAGGLSGLAPAYKQ 295 Query: 294 AKAALD-----GTDLLTLKGSTVSNSGYTKSAAKDSPSLTGRMPLIRSSLESGNAGHAKS 348 A+ A+D G + + S S + K L ++ S+L++ + Sbjct: 296 AREAVDYKWYLGKNRIITMDSLESAEPEEGAMRKYDYELNEKLI---SALKADDEDKISE 352 Query: 349 ILSDFTRKWKSSEHFSLGEADRIIQEFIILLGDIAVELDA-----------VPERLRSGK 397 + + L + + ++ +G + +EL A + E L + + Sbjct: 353 AVEMIFASLSYTRPDGLKYGRNLCMQLVLAIGQLLMELGAGDPELEVMEGELTEALYAKE 412 Query: 398 S-KGLRGLGISSDFASFGEFEAVLSSILDVYAGEISRSLAGDRSSVLENIKAYIDNHYFE 456 + K +RGL I S A+ GE I G ++V+E ++ YID +Y Sbjct: 413 TLKDMRGL-IESYLATVGE--------------HIREKRTGRVANVIERVRGYIDQNYAN 457 Query: 457 N-IKISMFTDKYFLSREYLMKLFKGQYGYGIHEYVQKVRMDKAKELLSDPALKIQDISER 515 + ++ +LS Y+ LFK + G + EY+ KVR+DKAKELL DP K DI Sbjct: 458 GGLTVADIGKAVYLSSTYVSLLFKQETGQTVGEYLTKVRVDKAKELLRDPQYKFYDICYA 517 Query: 516 LGYKDKNYFSKAFRNYYDCSPSEFR 540 +GY D +YFSK F+ +PS +R Sbjct: 518 IGYTDPSYFSKLFKKVTGVTPSAYR 542 >B1D5Y1.1 B1D5Y1_9BACL Two component transcriptional regulator, AraC family Length = 545 Score = 196 bits (497), Expect = 7e-48, Method: Compositional matrix adjust. Identities = 144/555 (25%), Positives = 256/555 (46%), Gaps = 29/555 (5%) Query: 1 MYKVLIIDDEEPLREAIHILGDWKGLGVDQVLEATDGRVGLEMLRKHKIDLALVDMKMPE 60 MYK+LI+DDE +R + +W G++ + EA DG V EM+ + DL L D++MP Sbjct: 1 MYKLLIVDDETTVRMGLQSYFNWSSFGIEIMGEADDGDVAFEMIGREAPDLVLTDVRMPN 60 Query: 61 LNGSQLLQIAEREFPDLLLIVISGYNDFEYTRQAIRSKVVDYLLKPVNRSDLNSALRKAM 120 ++G L ++ +P + +I +SG++D +Y + A++ VDY+ KPVN +L+S LR + Sbjct: 61 MDGITLARLINEHYPHVKIIFVSGHDDADYLKSAMKLSAVDYIFKPVNLEELSSVLRHVV 120 Query: 121 DVLEAKRKRESEFITRNITLNMSLPKLKEKMYLSIIERSFKNQSNEAFLPLIGADKPGN- 179 L+ +R + + L +P L+EK LS++ + Q + + P Sbjct: 121 SDLDEQRAEQQRKEELQVRLKEGMPVLREKFLLSLMGSGVQRQDIRERVQFLELSLPEEA 180 Query: 180 HFAVGVLRMLNVEQVRHARFHEDRDLLHFAVTNVINENSGGHFEAFSFASPRSEREFIAI 239 + V V+ + ++ +V R DR LL +++ N+ E H + F EF I Sbjct: 181 SYWVIVISVDDLPEVMSTRSERDRQLLWYSINNICQELIDSHMGGYVFEYQTG--EFAGI 238 Query: 240 FTLKGSYGE---DAAFLSLHHMKKTVSTLKELFGILCAGGLGQPYSEVMGIAQSYELAKA 296 +G+ E DAA L + L+ I G+ + + + Y+ A+ Sbjct: 239 LR-RGAESEVSGDAAEGLLELTSRIRDNLERWLKISVTIGISDRVTGLGNLGNCYKQARE 297 Query: 297 ALD-----GTDLLTLKGSTVSNSGYTKSAAKDSPSLTGRMPLI-----RSSLESGNAGHA 346 A++ G + + S S+ + SA GR + S+L++ N Sbjct: 298 AVNHKWYLGKNRIITMDSLESSEQASLSA--------GRYEFVYDEELTSALKAANPEKL 349 Query: 347 KSILSDFTRKWKSSEHFSLGEADRIIQEFIILLGDIAVELDAVPERLRSGKSKGLRGLGI 406 + +L + L + + + G + +EL+ E L S ++ L Sbjct: 350 REVLDAIFADLNRNRPDGLKYGRNVCMQIFLAAGQLLLELNMQSEELESAEAAVWESL-- 407 Query: 407 SSDFASFGEFEAVLSSILDVYAGEISRSLAGDRSSVLENIKAYIDNHYFE-NIKISMFTD 465 D + GE +L + L I G ++++E ++A ID Y ++ ++ Sbjct: 408 -LDRETLGEMRLILEAYLLAACERIGEKRTGKVANLVERVRAIIDRDYSNGSLTVTDIGR 466 Query: 466 KYFLSREYLMKLFKGQYGYGIHEYVQKVRMDKAKELLSDPALKIQDISERLGYKDKNYFS 525 + FL+ Y+ L+K + G + EY+ +VRM+KAKE+L DP K DI +GY D +YF+ Sbjct: 467 EVFLTPTYVSLLYKQETGQTVGEYMTQVRMEKAKEMLRDPQYKFYDICYAIGYTDPSYFT 526 Query: 526 KAFRNYYDCSPSEFR 540 K F+ +PS +R Sbjct: 527 KLFKKMTGVTPSGYR 541 >B1D907.1 B1D907_9BACL Two component transcriptional regulator, AraC family Length = 533 Score = 183 bits (464), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 150/567 (26%), Positives = 274/567 (48%), Gaps = 69/567 (12%) Query: 1 MYKVLIIDDEEPLREAIHILGDWKGLGVDQVLEATDGRVGLEMLRKHKIDLALVDMKMPE 60 M+KV+++DDE R+++ + D L V+ V EA +G LE++ K + + DM MP Sbjct: 1 MFKVMVVDDEPWGRKSVGKMIDELQLDVEVVAEARNGAEALELIPVSKPHIIVTDMNMPV 60 Query: 61 LNGSQLLQIAEREFPDLLLIVISGYNDFEYTRQAIRSKVVDYLLKPVNRSDLNSALRKAM 120 +NG Q L+ + + ++VISG++ FEY + A+ + +Y+LKPV+ +DL A+ KA Sbjct: 61 MNGQQFLEQLYHRYNHIKVVVISGHSQFEYMKAAVAYQACEYVLKPVSHADLKDAMVKA- 119 Query: 121 DVLEAKRKRESEFITRNITLNMSLPKLKEKMYL-SIIERSFKNQSN--EAFLPLIGADKP 177 ++A R S + + + KL+ + +L ++ R ++ L+ + Sbjct: 120 --IQASRSHMS--VEQRQQFANEMRKLRTETFLQNVTGRRIVGNADIVSQAAELLTSPAT 175 Query: 178 GNH-FAVGVLRMLNVEQVRHARFHEDRDLLHFAVTNVINENSGGHFEAFSFASPRSEREF 236 G + AV +LR ++ +F+ + DLL F++ N++NE + G + F S +R+ Sbjct: 176 GRYRLAVCMLRRFR--ELAETKFNGNADLLMFSIENMMNELTSGA-PLYVFKS--DDRQR 230 Query: 237 IAIFTLKGSYGEDAAFLSLHHMKKTVSTLKELFGILCAGGLGQPYSEVMGIAQSYELAKA 296 + + + S L +T S + +L+ ++ GL P + + +++E A Sbjct: 231 LCLLLSEPSMDGGTVREMLLPFHETTSRMLQLYAVV---GLSDPRERLDQLPEAFEEASE 287 Query: 297 ALDGTDLLTLKGS--TVSNSGYTKSAAKDSPSLTGRM------PLIRSSLESGNAGHAKS 348 L G+ TL+G+ +V ++G +P G M L++ ++ G + Sbjct: 288 RLYGS---TLRGTEFSVMSAG--------TPHERGEMLGGFDAKLLQQAIVGGQTASVRR 336 Query: 349 ILSDFTRKWKSSEHFSLGEADRIIQEFIILLGDIAVELDAVPERLRSGKSKGLRGLGISS 408 +L +F RK + SE ++ A + +++ G + G I++ Sbjct: 337 MLGEFARKAEMSESLTIRSAQKELRKL--------------------GAAAGSEWPAITT 376 Query: 409 DFASFGEFEAVLS----SILDVYAGEIS---------RSLAGDRSSVLENIKAYIDNHYF 455 + A+ S S L Y E+S R+ + D S+ + I AY+D HYF Sbjct: 377 ASPLLADQRAIDSVMTLSALHAYVAELSAAIEAHIRARASSSDASNPMSEIVAYLDGHYF 436 Query: 456 ENIKISMFTDKYFLSREYLMKLFKGQYGYGIHEYVQKVRMDKAKELLSDPALKIQDISER 515 E++ + +Y + YL + FK G EYV + RM+KA ELL + K+ DI+E Sbjct: 437 EDVGLIDMATRYHMDPSYLSRQFKAATGVNFIEYVTRKRMEKACELLRESDRKVSDIAEL 496 Query: 516 LGYKDKNYFSKAFRNYYDCSPSEFRLL 542 +GY+++ YFS+ F+ + +PSEFR L Sbjct: 497 VGYENQRYFSQVFKKFTGQTPSEFREL 523 >B3K421.1 B3K421_9BACI Response regulator receiver Length = 532 Score = 172 bits (436), Expect = 7e-41, Method: Compositional matrix adjust. Identities = 156/561 (27%), Positives = 249/561 (44%), Gaps = 54/561 (9%) Query: 1 MYKVLIIDDEEPLREAIHILGDWKGLGVDQVLEATDGRVGLEMLRKHKIDLALVDMKMPE 60 MY VLI DDE +RE + + DW+ +G EA +G E+L+ H DL + DM MP Sbjct: 1 MYNVLIADDEIEVREGLKLKVDWESMGFAISGEAGNGLEAEELLKSHSYDLLITDMNMPV 60 Query: 61 LNGSQLLQIAEREFPDLLLIVISGYNDFEYTRQAIRSKVVDYLLKPVNRSDLNSALRKAM 120 ++G +LL + P + +I+I+GY DF+Y R +RS+ +DYLLKPV R DL SAL K Sbjct: 61 MDGVRLLDVCRSHNPTIQIIIITGYEDFQYARAGVRSQAMDYLLKPVARDDLKSALSKIK 120 Query: 121 DVLEAKRKRESEFITRNITLNMSLPKLKEKMYLSIIERSFKNQSNEAFLP-------LIG 173 L+ RK + L+ ++KE+ L ++ ++ A +P L Sbjct: 121 HELDKNRKVRDDSEMLQWRLSQYYKEMKERFLLDLVR---GDRLPSASMPERIRLFHLED 177 Query: 174 ADKPGNHFAVGVLRMLNVEQVRHARFHEDRDLLHFAVTNVINENSGGHFEAFSFASPRSE 233 F +R +++ R E L V + I E+ G + F A+ Sbjct: 178 WQDGRVCFITAGMRESGMQKAPEGRAPEQLRLPFQMVCHEIAESYPGGVQVFHDAAHPGI 237 Query: 234 REFIAIFTLKGSYGEDAAFLSLHHMKKTVSTLKELFGILCAGGLGQPYSEVMGIAQSYEL 293 FIA+ ++ ++ + K V+ + GLG P S + + Y Sbjct: 238 MHFIALDGIQHAFAD-----------KLVAQASSYLTVEVQVGLGLPVSGLERWKEGYIH 286 Query: 294 AKAALDGTDLLTLKGSTVSNSGYTKSAAKDSPSL---TGRM---PLIRSSLESGNAGHAK 347 + LL + N SP L T R LIR LES + Sbjct: 287 S--------LLAWNLAGRQNGPDQAPVTDQSPLLPDETSRALHRCLIRGELES-----FR 333 Query: 348 SILSDFTRKWKSSEHFSLGEADRIIQEFIILLGDIAVELDAVPERLRSGKSKGLRGLGIS 407 SI+ + + E F L A + F I L + D + S+G L IS Sbjct: 334 SII-----RRELGESFRLSPARLVRSLFQITLIMESAAFDNI------RHSRGGGPLWIS 382 Query: 408 SDFASFGEFEAVLSSILDVYAGEISRSL--AGDR-SSVLENIKAYIDNHYFENIKISMFT 464 ++ + E +L +A + +L +GDR ++++E+ K YI+ +Y + + ++ Sbjct: 383 PEWVLWLETPEQAERLLMQWAQDFVDNLTESGDRDATLIESAKRYIEENYMQELSLTSLA 442 Query: 465 DKYFLSREYLMKLFKGQYGYGIHEYVQKVRMDKAKELLSDPALKIQDISERLGYKDKNYF 524 ++Y Y ++FK G +YV +VRM A LL + L + DI+E G+ YF Sbjct: 443 EQYNYHPTYFSEMFKEGAGVSFIQYVTEVRMKHAVRLLQETRLTVWDIAELTGFSSPGYF 502 Query: 525 SKAFRNYYDCSPSEFRLLLTE 545 S F+ ++ SPSEFRL +E Sbjct: 503 SSKFKKMFNQSPSEFRLSQSE 523 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,089,022,407 Number of extensions: 127394229 Number of successful extensions: 425801 Number of sequences better than 1.0e-05: 7153 Number of HSP's gapped: 437397 Number of HSP's successfully gapped: 7654 Length of query: 548 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 407 Effective length of database: 1,732,333,088 Effective search space: 705059566816 Effective search space used: 705059566816 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 134 (56.2 bits)