BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0341.0025.p (614 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1D9L0.1 B1D9L0_9BACL Histidine kinase internal region 652 0.0 A6CLU9.1 A6CLU9_9BACI Putative uncharacterized protein 214 3e-53 B1DAF1.1 B1DAF1_9BACL Integral membrane sensor signal transducti... 186 9e-45 C0C1J1.1 C0C1J1_9CLOT Putative uncharacterized protein 183 4e-44 B1D7N6.1 B1D7N6_9BACL Integral membrane sensor signal transducti... 183 5e-44 >B1D9L0.1 B1D9L0_9BACL Histidine kinase internal region Length = 617 Score = 652 bits (1683), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/613 (56%), Positives = 424/613 (69%), Gaps = 17/613 (2%) Query: 3 ERVSRRLANKXXXXXXXXXXXVVASLTFISYGMLRKESVNNSISSTRSNLLLVGRNLESY 62 ERVS RL NK VV SLTFISY ML++E++NNSI+ST +NLLLV +NLE Y Sbjct: 16 ERVSSRLVNKLILLFTTIIILVVGSLTFISYKMLQREALNNSIASTSNNLLLVNKNLEDY 75 Query: 63 LDGIGQLSLPQISYDEFNYAILHESEDYASKMYVEDYLKNLYFSRS--DLEAIYLYVIKE 120 L G+ QLSLPQI+YDE +AI H S DYASKMYVEDYL+N+YFSRS DLEAIYLY ++ Sbjct: 76 LAGMEQLSLPQINYDELAFAITHASTDYASKMYVEDYLRNMYFSRSNEDLEAIYLYFVRS 135 Query: 121 HKYYYVTKENYNITVRVVEHPPIENLPWYKRALASPFNRSYQSFVKERTPEESQGDYPIN 180 YY + KEN++I +R + I + WYK+A+ S N++YQSF+ E +G Y ++ Sbjct: 136 GTYYTIAKENFDIKIRSGQADSIPTMSWYKQAMDSGTNQAYQSFL---LSNEERG-YDMD 191 Query: 181 SEKSFMGYHRLLRSIVTREPQAVLSLYFNSSVTDEIMKDIPFSDGEHLMYISPDNEPFVV 240 +SFM YHR+LRSI TR PQAV+S Y+N S ++IMKDIP G+HL ++SPDN PF + Sbjct: 192 PSRSFMAYHRVLRSISTRAPQAVVSFYYNKSTINKIMKDIPEDTGQHLFFLSPDNVPFAL 251 Query: 241 DDREFYLQSEQAGLLEQLTPAQG---GRLTWSDTE-QKYLVMYDISQKEGWKLVKPIPYK 296 D+R Y +GLL+Q+ G LTW E KYLV+Y++ +EGWKLVKPIPYK Sbjct: 252 DNRTSYESMVGSGLLKQIIKTDGTGANGLTWKSPEDNKYLVVYNVGAQEGWKLVKPIPYK 311 Query: 297 QIYEAATTTRKLSYXXXXXXXXXXXXXXXXXXNRITNPLKNLSLQMKRFSTGSFDAEAAV 356 ++Y AA TTR L++ N +T PLK LS QMKRFSTG F+A V Sbjct: 312 ELYAAAKTTRNLNFMIGLLFLLLAVVLITYFSNAVTKPLKLLSQQMKRFSTGDFEASTEV 371 Query: 357 DGNDEIAYLSRHFNKMVEKTNELINERYKMKIVEKNAVLKALEAEINPHFLYNALQAIST 416 G DE+AYLSR FN+MV +TNELI ERYKMK+VEKNA+LKALEAEINPHFLYNALQAIST Sbjct: 372 VGRDELAYLSRQFNQMVSQTNELITERYKMKLVEKNAILKALEAEINPHFLYNALQAIST 431 Query: 417 KALKNNNDDIVEMVDNLALTLRYCISGRDVVQAREELKHIERYLALQKARFGSRMQVEYD 476 KALK DI +MVD LALTLRYCISG+D+V+A EEL HIERY++LQKARFG R+Q+ D Sbjct: 432 KALKAERFDIADMVDALALTLRYCISGKDIVRASEELLHIERYMSLQKARFGGRLQLVID 491 Query: 477 WNDSLLELRIPKLSIQTLVENCIKHALEKVSSTVTIRIEAHITAAHSVISVLDDGPGITE 536 W+ L EL +PKLS+QTLVEN IKH +E VSS V IRI A H+ I V D+GPG Sbjct: 492 WDQDLKELELPKLSLQTLVENAIKHGVEMVSSPVAIRISARAAGGHAFIIVNDNGPGFAP 551 Query: 537 QRLQQVLSSLQIQWXXXXXXXXXXXXXXSIGLKNLNTRLKLLYGEEAGLVIAGNEQGTRI 596 RL+ VL S + W S+GL NLNTRLKLLYG + LVI + GT + Sbjct: 552 GRLKDVLESFEADW------NERAEEEGSVGLVNLNTRLKLLYGTSSQLVIRTSPSGTEM 605 Query: 597 DMRLPRGGLGQHV 609 +M +PRGG GQHV Sbjct: 606 EMLIPRGG-GQHV 617 >A6CLU9.1 A6CLU9_9BACI Putative uncharacterized protein Length = 603 Score = 214 bits (544), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 167/597 (27%), Positives = 273/597 (45%), Gaps = 25/597 (4%) Query: 26 ASLTFISYGMLRKESVNNSISSTRSNLLLVGR-NLESYLDGIGQLSLPQISYDEF-NYAI 83 S I+Y + K S+ + SNLL G+ NLE+Y++ + L+L + +F NY Sbjct: 23 GSSIIITY-LYTKNSIEEEVVQESSNLLYQGKINLENYINELSGLTLSLYNNPDFINYMR 81 Query: 84 LHESE-DYASKMYVEDYLKNLYFSRSDLEAIYLYVIKEHKYYYVTKENYNITVRVVEHPP 142 +SE DY + V++ ++ ++ ++ + + + + TK + TV Sbjct: 82 SPQSESDYLTIGLVKNVVQTFLYTEKTIKEVTITFADDDRVISATKHS---TVVFSMREG 138 Query: 143 IENLPWYKRALASPFNRSYQSFVKERTPEESQGDYPINSEKSFMGYHRLLRSIVTREPQA 202 +A SP+N + P Q + KS HR L +I E Sbjct: 139 ASEQEALMKAARSPYNLNI-------APAYPQQENERKRSKSIATIHRALINIPADEVLG 191 Query: 203 VLSLYFNSSVTDEIMKDIPFSDGEHLMYISPDNEPFVVDDREFYLQSEQAGLLEQLTPAQ 262 +SL ++ K++ +D E ++P+ E D + L ++++T Sbjct: 192 YISLEILPDKILDLSKNLYNTDTEEFYLLTPEGEVIYSSDGDTSLNKRSQEWIQEITDGN 251 Query: 263 --GGRLTWSDTEQKYLVMYD--ISQKEGWKLVKPIPYKQIYEAATTTRKLSYXXXXXXXX 318 G L W ++MYD GW LVK + Y +YE+A + K++ Sbjct: 252 ETSGTLEWQKDSFNGVMMYDRLSPSAGGWILVKRVSYANLYESAFSVAKINILFGFVGLS 311 Query: 319 XXXXXXXXXXNRITNPLKNLSLQMKRFSTGSFDAEAAVDGNDEIAYLSRHFNKMVEKTNE 378 +IT+P++ L +++ G E+ G DEI L F +M+ + N Sbjct: 312 LVILSILFVSFKITSPIRVLLHNIQQVEKGEMKIESQSFGTDEIGLLGSRFQQMIGRINH 371 Query: 379 LINERYKMKIVEKNAVLKALEAEINPHFLYNALQAISTKALKNNNDDIVEMVDNLALTLR 438 LIN YK+++ K LK L+++INPHFLYNALQ+I T ALKN I ++ +L+ +R Sbjct: 372 LINREYKLELENKTNQLKVLQSQINPHFLYNALQSIGTIALKNKVPQIYTLITHLSKIMR 431 Query: 439 YCIS-GRDVVQAREELKHIERYLALQKARFGSRMQVEYDWNDSLLELRIPKLSIQTLVEN 497 Y + D+V +E+ + YL LQK RFG + + + L E+++PK+ +Q ++EN Sbjct: 432 YGMDMEEDIVSLNKEINYTRAYLLLQKERFGDHLDYSIEVEEGLKEVKVPKMLLQPIIEN 491 Query: 498 CIKHALEKVSSTVTIRIEAHITAAHSVISVLDDGPGITEQRLQQVLSSLQIQWXXXXXXX 557 KH + IR+ VI+V D+G G+T Q+LQ++ Q Sbjct: 492 YFKHGFDIREGIGRIRLNCFSEHDELVITVEDNGAGVTAQKLQEIYEHFQTD------IK 545 Query: 558 XXXXXXXSIGLKNLNTRLKLLYGEEAGLVIAGNEQGTRIDMRLPRGGLGQHVQSTDY 614 SIGLKN+ RLKL Y ++A L + E G R+ MRLP G +S Y Sbjct: 546 NTTGENTSIGLKNVFVRLKLYYNQQASLELQNLEGGFRVTMRLPVQMEGDTHESNHY 602 >B1DAF1.1 B1DAF1_9BACL Integral membrane sensor signal transduction histidine kinase Length = 596 Score = 186 bits (471), Expect = 9e-45, Method: Compositional matrix adjust. Identities = 106/330 (32%), Positives = 172/330 (52%), Gaps = 9/330 (2%) Query: 275 YLVMYDISQKEGWKLVKPIPYKQIYEAATTTRKLSYXXXXXXXXXXXXXXXXXXNRITNP 334 Y+ Y +S+ GWK+ +P ++ A TR ++ +T Sbjct: 270 YICSYSVSKDTGWKIFAFVPVDYLHHDAQLTRNVTLTTTIGIIGFALLVSVILAFMMTRS 329 Query: 335 LKNLSLQMKRFSTGSFDAEAAVDGNDEIAYLSRHFNKMVEKTNELINERYKMKIVEKNAV 394 L+ ++ M+ G+ D V DE+ L FN+M+ + ELI+E Y ++ +K A Sbjct: 330 LRQMTDLMRTVRGGNLDVSFDVKQKDEVGILGTEFNRMLRRMKELISEIYVIQSRKKEAD 389 Query: 395 LKALEAEINPHFLYNALQAISTKALKNNNDDIVEMVDNLALTLRYCIS-GRDVVQAREEL 453 L+AL+++INPHF+YN L+ I A N+++++ EM L LRY I+ GR+ V+ REEL Sbjct: 390 LEALQSQINPHFIYNTLETIRMTAEINDDEEVAEMTFTLGKLLRYSINRGRETVELREEL 449 Query: 454 KHIERYLALQKARFGSRMQVEYDWNDSLLELRIPKLSIQTLVENCIKHALEKVSSTVTIR 513 +H+ERYL L + RF +R V +D L+ + KL+ Q +VEN I H +E + VTIR Sbjct: 450 QHLERYLQLLRYRFSNRFVVAFDIPQELMNFPVMKLTFQPIVENAILHGMEGKPNEVTIR 509 Query: 514 IEAHITAAHSVISVLDDGPGITEQRLQQVLSSLQIQWXXXXXXXXXXXXXXSIGLKNLNT 573 + A + + S+ D+G G+ L + ++ +GL+N+N Sbjct: 510 LSAELKEQLLIFSIKDEGAGMDGMTLDLLRQAMN-------GTRESASSKTGVGLRNVNE 562 Query: 574 RLKLLYGEEAGLVIAGN-EQGTRIDMRLPR 602 R+KL YGE GL I +GT ++++LPR Sbjct: 563 RIKLHYGETYGLEIESKWGEGTTVNLKLPR 592 >C0C1J1.1 C0C1J1_9CLOT Putative uncharacterized protein Length = 601 Score = 183 bits (465), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 126/406 (31%), Positives = 202/406 (49%), Gaps = 11/406 (2%) Query: 202 AVLSLYFNSSVTDEIMKDIPFSDGEHLMYISPDNEPFVVDDREFY-LQSEQAGLLEQLTP 260 L ++ NS + +++ + ++ + + I + + D ++ Q +A + E LT Sbjct: 198 GCLIVHMNSDILGNVLQSVNSNEYQQCLIIDNNKKIIYHPDSDYIGTQYREARVSELLTM 257 Query: 261 AQGGRLTWSDTEQKYLVMYDISQKEGWKLVKPIPYKQIYEAATTTRKLSYXXXXXXXXXX 320 G S +E+ YLV + S GW ++ + K I ++ R Sbjct: 258 ENG--YMESLSEKGYLV-FSTSAVTGWSVISVVDNKYIMDSINRLRLFLILTAVFCVVLS 314 Query: 321 XXXXXXXXNRITNPLKNLSLQMKRFSTGSFDAEAAVDGNDEIAYLSRHFNKMVEKTNELI 380 I++P+ L +M + G FD AA +DEI L+ F+KMVE+T +LI Sbjct: 315 VYFASYISKTISDPVARLQRKMYQVGEGDFDIRAATGASDEIGQLTLSFDKMVERTKQLI 374 Query: 381 NERYKMKIVEKNAVLKALEAEINPHFLYNALQAISTKALKNNNDDIVEMVDNLALTLRYC 440 Y+ +I +K A L AL+A+INPHFLYN LQ I A + D+I + L+ RY Sbjct: 375 ENVYQSEIYQKEAELNALQAQINPHFLYNTLQTIDMMAEEEGADEISDACQALSKIFRYS 434 Query: 441 IS-GRDVVQAREELKHIERYLALQKARFGSRMQVEYDWNDSLLELRIPKLSIQTLVENCI 499 I+ G++ V ++E+ HIE Y+ +QK RFG +++V YD + EL I KL IQ +VEN + Sbjct: 435 INRGQEFVHVQDEIVHIENYMLIQKLRFGGKLEVRYDIQNECRELYIVKLLIQPMVENAV 494 Query: 500 KHALEKV--SSTVTIRIEAHITAAHSVISVLDDGPGITEQRLQQVLSSL-QIQWXXXXXX 556 H +E V VTIR+ ++ V D+G GI +L ++ L + Sbjct: 495 VHGMENVLDKCYVTIRVYRKEDCLYA--EVEDNGTGIAPGQLMELNEKLARSAEQKMVHE 552 Query: 557 XXXXXXXXSIGLKNLNTRLKLLYGEEAGLVIAGNE-QGTRIDMRLP 601 SIGL+N N R+KL +G+E G+ I E GT++ ++LP Sbjct: 553 VDYVKNHRSIGLENTNARIKLYFGQEYGITITSEEGTGTKVCIKLP 598 >B1D7N6.1 B1D7N6_9BACL Integral membrane sensor signal transduction histidine kinase Length = 610 Score = 183 bits (465), Expect = 5e-44, Method: Compositional matrix adjust. Identities = 160/582 (27%), Positives = 268/582 (46%), Gaps = 59/582 (10%) Query: 51 NLLLVGRN-LESYLDGIGQLSLP---QISYDEFNYAILHESE---------DYASKMYVE 97 NLL +G+N + Y+D I + SL I+ YA++ + D + + + Sbjct: 49 NLLALGKNNILGYMDKINENSLDVYLNINKSNSLYALIERGQSPNVNVPMFDEKNNLQIY 108 Query: 98 DYLKNLYFSRSDLEAIYLYVIKEHKYYYVTKENYNITVRVVEHPPIENLPWYKRALASPF 157 ++ N+Y S + + I L I + K Y+ + R + P L W +SP Sbjct: 109 AHMLNIYQSTNGIHQIQLQ-IGDGKLTYLMARGF--FRRGINQP----LEWPTEHGSSP- 160 Query: 158 NRSYQSFVKE-RTPEESQGDY--PINSEKSFMGYHRLLRSIVTREPQ----AVLSLYFNS 210 + FV+ T D+ + E F LR + R P LS+ S Sbjct: 161 ----KPFVEATHTSAHYNLDWSHAVKEESVFT-----LRRPIIRTPSDEVIGYLSMDVKS 211 Query: 211 SVTDEIMKDIPFSDGEHLMYISPDNEPFVV-----DDREFYLQSEQAGLLEQLTPAQGGR 265 ++I + + S E L YI + FV +D++ ++Q +Q + G Sbjct: 212 DELNQICRQLTMSSEEQL-YIIDRSRNFVCSVNGQEDQDRLKWTDQVLASKQ----ENGV 266 Query: 266 LTWSDTEQKYLVMYDI--SQKEGWKLVKPIPYKQIYEAATTTRKLSYXXXXXXXXXXXXX 323 + W D +V+YD + W +VK +PY +YE+AT R ++ Sbjct: 267 IKWQDQSFSGIVIYDTLSTNYMDWVVVKQLPYSYLYESATAIRTINTSVIAIFMVLAVIA 326 Query: 324 XXXXXNRITNPLKNLSLQMKRFSTGSFDAEAAVDGNDEIAYLSRHFNKMVEKTNELINER 383 + T P+K L + + +G+F+ VD DEI L+R FN M++ +LIN Sbjct: 327 SFLVSYQFTKPIKRLIGHINQVQSGNFNVVVPVDRKDEIGILARRFNTMIQTIRDLINSE 386 Query: 384 YKMKIVEKNAVLKALEAEINPHFLYNALQAISTKALKNNNDDIVEMVDNLALTLRYCI-S 442 Y+++I K L+A++A+INPHFLYNALQ+I T AL + ++ ++A +RY + + Sbjct: 387 YRLEIANKTNQLRAMQAQINPHFLYNALQSIGTLALHAGAPKVYTLITSIAKMMRYNMNT 446 Query: 443 GRDVVQAREELKHIERYLALQKARFGSRMQVEYDWNDSLLELRIPKLSIQTLVENCIKHA 502 +V EL H + YL LQ+ RF ++ V YD + + L +++PK+ +Q LVEN KH Sbjct: 447 SESIVPFSMELNHAKAYLELQQQRFNEQLTVHYDIDPASLSVQVPKMLLQPLVENYFKHG 506 Query: 503 LEKVSSTVTIRIEAHITAAHS--VISVLDDGPGITEQRLQQVLSSLQIQWXXXXXXXXXX 560 E + +R+ + +T S I + D+G G+ +L+++ L Sbjct: 507 YETSGRSGVLRLFSEVTDDGSWLTIRIEDNGSGMDPDKLRELRQLL------FRSTGALL 560 Query: 561 XXXXSIGLKNLNTRLKLLYGEEAGLVIAGNEQGT-RIDMRLP 601 SIG+ N+ RLKL Y EEA + I + G + +R+P Sbjct: 561 EEQKSIGISNVWMRLKLYYNEEAEMSIDSSPSGGFTVTLRIP 602 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.133 0.374 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,173,838,339 Number of extensions: 124787862 Number of successful extensions: 368465 Number of sequences better than 1.0e-05: 1970 Number of HSP's gapped: 365691 Number of HSP's successfully gapped: 1970 Length of query: 614 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 472 Effective length of database: 1,722,912,073 Effective search space: 813214498456 Effective search space used: 813214498456 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 134 (56.2 bits)