BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0341.0016.p (578 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DDD2.1 B1DDD2_9BACL Histidine kinase internal region 776 0.0 A9U7Y1.1 A9U7Y1_PHYPA Predicted protein (Fragment) 478 e-133 B1DDM2.1 B1DDM2_9BACL Integral membrane sensor signal transducti... 363 4e-98 B3KB78.1 B3KB78_9BACI Histidine kinase internal region 360 2e-97 B3K7P4.1 B3K7P4_9BACI Histidine kinase internal region 346 4e-93 >B1DDD2.1 B1DDD2_9BACL Histidine kinase internal region Length = 592 Score = 776 bits (2005), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/583 (62%), Positives = 457/583 (78%), Gaps = 11/583 (1%) Query: 3 KLKKYMPFTYKMMIPYLLLVLLTDVTIGYISYSMLTDSRTEMAESNIRTGMEQARNNIRY 62 +++ +MPFTYKMMI YLLLVL+TD IGY SY+ML SRTEMAE+NI+T MEQ NN+ Y Sbjct: 4 RMRTFMPFTYKMMISYLLLVLVTDAVIGYFSYTMLVQSRTEMAETNIKTAMEQTENNLSY 63 Query: 63 QMDEIQRMSDNLFGSQPFQRALELKGTPFEIYLAMLDEIVPQITAPLQLFGNKIRFMLYT 122 Q+DEIQRMSD LFGS FQRAL+ KG P + YL MLDEIVPQI APL L+GN IR ++YT Sbjct: 64 QLDEIQRMSDTLFGSLSFQRALQKKGDPLQTYLTMLDEIVPQIQAPLHLYGNHIRLLVYT 123 Query: 123 PNSQLNIVSGDNLNEPIYDSDYYILPLKDIADSGWYQSLKDSKRDNLWLQIDTDQKLDNL 182 N LN V GD++ E I DSDYYILP +I + W+ +++DS +DN+WLQ+DTD+ L+N+ Sbjct: 124 TNGYLNEVDGDSMYEEIKDSDYYILPYSEITNKSWFNAIQDSDKDNIWLQVDTDRTLNNI 183 Query: 183 SHVRRLVNFSDYKTVIGYVRITVSLEDLFGGFDTFPVEEGITLRLVEETTGDILFQRGPA 242 SH R+LV+++DYKT+IGYVRIT L+DL G F FP EEG+ LRLV+ + +L+QRG Sbjct: 184 SHFRKLVSYNDYKTIIGYVRITTRLDDLLGDFKAFPTEEGLILRLVDTSRDTVLYQRGDD 243 Query: 243 NYDDA-----------GGDYLSLHEKIPGSSFVIESLVPDTYLTKDAGRLGRVIFALCAL 291 D G YL + KIP +SF IE+LVP+ YL KDAG+LG VIF +C + Sbjct: 244 GDTDGKAAAGTMPEEDNGTYLVMQNKIPNTSFEIETLVPNEYLRKDAGKLGSVIFYVCLI 303 Query: 292 SFLVMTVIGYVVARLSGRKMSRIVGLVRSFQEGNFQKRIRFSGNDEFVQIADSFNVMATN 351 SFLVM++IG++VARLSGRKM RIV +RSFQ+G+FQKR+RFSGNDEFV IA +FN MA N Sbjct: 304 SFLVMSLIGFLVARLSGRKMRRIVTFLRSFQQGSFQKRLRFSGNDEFVHIAGAFNDMAEN 363 Query: 352 IQELINSVYVQGIQKKQAELEALQAQINPHFLYNTLSTISSLANLGEIEKVTGMVQGLSR 411 IQ+LI VYV+GIQKKQAELEALQAQINPHFLYNTLSTI SLANL E EKVTGMV+GL++ Sbjct: 364 IQDLIKKVYVEGIQKKQAELEALQAQINPHFLYNTLSTIGSLANLSETEKVTGMVEGLAK 423 Query: 412 FYRLTLNQGNVYIELEKELEQVATYLDIQRVKYADAFTVYVDVEEEILHMQVIKLVLQPF 471 FYRL+LN G V+I L KELEQV YLDIQR+KYA F V++D+E E+ +VIKL+LQPF Sbjct: 424 FYRLSLNDGQVFIPLAKELEQVEAYLDIQRIKYAGKFDVHIDMERELADCKVIKLILQPF 483 Query: 472 VENVFKHAWFGETIAIRLTGRRVGDNIELKVIDNGIGMRPEDIKRMMQGPSQAGGYGVKN 531 VEN+FKHAWFG IAIR++GR +G+ +ELKVID GIGM+P+ +K +M P Q+GGYG++N Sbjct: 484 VENIFKHAWFGSHIAIRISGRAIGNKVELKVIDTGIGMKPDALKAVMAQPGQSGGYGIRN 543 Query: 532 VNERIKLRYGDDYGVTIASFFGAGTTVRLLLPAGMKDNEEMDE 574 V++RIKLRYGD+YG+ I S FG GTTVR+LLP + N + +E Sbjct: 544 VDDRIKLRYGDEYGIEIGSVFGGGTTVRILLPIDRQGNVDEEE 586 >A9U7Y1.1 A9U7Y1_PHYPA Predicted protein (Fragment) Length = 361 Score = 478 bits (1230), Expect = e-133, Method: Compositional matrix adjust. Identities = 231/363 (63%), Positives = 297/363 (81%), Gaps = 3/363 (0%) Query: 196 TVIGYVRITVSLEDLFGGFDTFPVEEGITLRLVEETTGDILFQRGPANYDDAGGDYLSLH 255 TVIGY+RIT SL++L G F+ FP E+GITL+L+++ + + +Q+G A D A YL+L+ Sbjct: 1 TVIGYIRITTSLDELLGRFEAFPEEKGITLQLLDDQSEAVTYQKGEA--DPAENGYLALN 58 Query: 256 EKIPGSSFVIESLVPDTYLTKDAGRLGRVIFALCALSFLVMTVIGYVVARLSGRKMSRIV 315 E IPG+ + + +LV YL +DA RL +I +C+ SF VM +IG +VARLSGRKM +IV Sbjct: 59 EAIPGTGYSLRALVSQEYLQEDAKRLRLLILGVCSASFAVMALIGLLVARLSGRKMRKIV 118 Query: 316 GLVRSFQEGNFQKRIRFSGNDEFVQIADSFNVMATNIQELINSVYVQGIQKKQAELEALQ 375 L++SFQ+G+F+KRIRF G DEFVQIA +FN MA++I+ELINSVYVQG+ +KQAELEALQ Sbjct: 119 TLLQSFQDGSFEKRIRFGGRDEFVQIAQAFNNMASHIKELINSVYVQGLSRKQAELEALQ 178 Query: 376 AQINPHFLYNTLSTISSLANLGEIEKVTGMVQGLSRFYRLTLNQGNVYIELEKELEQVAT 435 AQINPHFLYNTLSTISSLAN+G+ ++VT MV+GLSRFYRL+LN G VYI L ELEQ+ T Sbjct: 179 AQINPHFLYNTLSTISSLANMGQAKEVTEMVKGLSRFYRLSLNGGKVYIPLGLELEQIQT 238 Query: 436 YLDIQRVKYADAFTVYVDVEEEILHMQVIKLVLQPFVENVFKHAWFGETIAIRLTGRRVG 495 YLDIQRVKYAD+FTVY D+EE I +QV+KL+LQPFVEN+FKHAWFG++I I ++GR VG Sbjct: 239 YLDIQRVKYADSFTVYTDIEEGIRDLQVMKLILQPFVENIFKHAWFGDSIGILISGRVVG 298 Query: 496 DNIELKVIDNGIGMRPEDIKRMMQGPSQ-AGGYGVKNVNERIKLRYGDDYGVTIASFFGA 554 +ELK+IDNGIGMRP+ ++ +M GPS+ GGYG++NV+ERIKLRYG +YGV AS +GA Sbjct: 299 GTLELKIIDNGIGMRPDALREIMSGPSRNEGGYGIRNVDERIKLRYGPEYGVDAASIYGA 358 Query: 555 GTT 557 GTT Sbjct: 359 GTT 361 >B1DDM2.1 B1DDM2_9BACL Integral membrane sensor signal transduction histidine kinase Length = 588 Score = 363 bits (931), Expect = 4e-98, Method: Compositional matrix adjust. Identities = 200/574 (34%), Positives = 333/574 (58%), Gaps = 15/574 (2%) Query: 5 KKYMPFTYKMMIPYLLLVLLTDVTIGYISYSMLTDSRTEMAESNIRTGMEQARNNIRYQM 64 +K++PF K++I Y++L+++ GY + ++TDS + I+ ++Q +N+ Y++ Sbjct: 13 RKFIPFGIKLLISYMMLIIIPIFLFGYFASDIMTDSIRSNTTNTIKGTLKQIEDNVVYKL 72 Query: 65 DEIQRMSDNLFGSQPFQRALELKGTPFEIYLAMLDEIVPQITAPLQLFGNKIRFMLYTPN 124 ++ R+SD L+ + L + Y A ++P+ + + +Y N Sbjct: 73 EDTVRLSDLLYYDTTLSKQLLHYEEGWVSYEATTKLLLPKFRQTIDSTNRSMWLSVYLRN 132 Query: 125 SQLNIVSGDNLN-EPIYDSDYY--ILPLKDIADSGWYQSLKDSK--RDNLWLQIDTDQKL 179 L + D N +P+ + +L L I WY+S + W QI+ D + Sbjct: 133 ETLPEIYYDTKNIDPLAMKGKFFDLLHLNRITQKPWYKSYPAEQYGETQEWKQIEDDGRY 192 Query: 180 DNLSHVRRLVNFSDYK-TVIGYVRITVSLEDLFGGFDTFPVEEGITLRLVEETTGDILFQ 238 + +S +RRLV+ K IG++RI+V L D+F D+ + G TL + + + +IL+ Sbjct: 193 NRISMLRRLVDLESAKPKEIGFMRISVYLSDMFQSVDSRKIGVGSTL-FITDGSRNILYA 251 Query: 239 RGPAN------YDDA-GGDYLSLHEKIPGSSFVIESLVPDTYLTKDAGRLGRVIFALCAL 291 G +D+ +YL + + +PG ++ + ++VP + L KD ++ + +C+ Sbjct: 252 SGATEQSTEQLWDEGRSKNYLVIRQPLPGLNWSLTAMVPSSVLEKDTQKVKLLTLVICSA 311 Query: 292 SFLVMTVIGYVVARLSGRKMSRIVGLVRSFQEGNFQKRIRFSGNDEFVQIADSFNVMATN 351 S +++ ++ V+R R++ +++ +++SF++G+FQ+RI +SGNDEF IA S N + Sbjct: 312 SCVLILLVATFVSRTFSRRVLKVMSVLQSFRQGDFQRRIHYSGNDEFTTIASSLNELGKR 371 Query: 352 IQELINSVYVQGIQKKQAELEALQAQINPHFLYNTLSTISSLANLGEIEKVTGMVQGLSR 411 Q LI VY ++KK+AELE LQAQINPHFLYNTLS+IS LA G++EK MV L++ Sbjct: 372 TQNLIEEVYTTNLKKKEAELETLQAQINPHFLYNTLSSISRLAKFGQVEKQHQMVMNLAK 431 Query: 412 FYRLTLNQGNVYIELEKELEQVATYLDIQRVKYADAFTVYVDVEEEILHMQVIKLVLQPF 471 FYRL+LN+G I + KE+EQV Y+DIQ++KY D + ++ EI+ + +KL++QPF Sbjct: 432 FYRLSLNEGQTIIPIVKEIEQVRAYMDIQQIKYGDRVQIDYNISPEIVDLATVKLIVQPF 491 Query: 472 VENVFKHAWFGETIAIRLTGRRVGDNIELKVIDNGIGMRPEDIKRMMQGPS-QAGGYGVK 530 VENV +HAW G+ I I+++G G+ + L V DNG GM E I + G + GYG++ Sbjct: 492 VENVLEHAWRGDQIDIQVSGYLEGEVVHLLVADNGNGMPQETIFHIFSGEGVERVGYGIR 551 Query: 531 NVNERIKLRYGDDYGVTIASFFGAGTTVRLLLPA 564 NV+ERI+L YG D+GV I S G GT V + +PA Sbjct: 552 NVHERIQLYYGKDFGVAIESAEGEGTCVHIRIPA 585 >B3KB78.1 B3KB78_9BACI Histidine kinase internal region Length = 578 Score = 360 bits (924), Expect = 2e-97, Method: Compositional matrix adjust. Identities = 209/576 (36%), Positives = 321/576 (55%), Gaps = 40/576 (6%) Query: 15 MIPYLLLVLLTDVTIGYISYSMLTDSRTEMAESNIRTGMEQARNNIRYQMDEIQRMSDNL 74 M Y + +++ + +G I+ + S E +NI+ + Q NI Y+M+++ R+SD L Sbjct: 1 MFSYCVFIIIPVLLVGQIANQVFVKSTREQTYNNIQGTLHQMSENISYKMEDMIRISDML 60 Query: 75 FGSQPFQRALELKGTPFEIYLAMLDEIVPQITAPLQLFGNKIRFMLYTPNSQLNIVSGDN 134 + F L + + Y ++ ++P++ + +I +Y N D+ Sbjct: 61 YFDTTFNSRLRFTESAWISYDTTINVLIPKLETAVSTANRRIWLSIYLRN--------DD 112 Query: 135 LNEPIYDSDYYILPLKD------------IADSGWYQSLKDSKRDNL-----WLQIDTDQ 177 L E IYDS Y PL + D WY+ K +N W QI+ D Sbjct: 113 LRE-IYDSYTYTDPLDSNKRLFDIYQYDRLEDRSWYKLY--PKEENYGVTLQWKQIEDDV 169 Query: 178 KLDNLSHVRRLVNFSDY--KTVIGYVRITVSLEDLFGGFDTFPVEEGITLRLVEETTGDI 235 +S +RRLV+ S IG++R+ VS+ DLF D + +G L L + G + Sbjct: 170 SNGRISLLRRLVDISSTIKPQEIGFMRMNVSMTDLFESMDYKKIGDGTALYL-SDAQGRV 228 Query: 236 LFQRGPANYD-------DAGGDYLSLHEKIPGSSFVIESLVPDTYLTKDAGRLGRVIFAL 288 + G + + GD L + + IP + + ++VP + KD ++ + + + Sbjct: 229 VLSSGGKSTNVFKEKELRKNGDLL-IRKPIPQLGWDLIAVVPAQIVEKDTVKIRNLTYLI 287 Query: 289 CALSFLVMTVIGYVVARLSGRKMSRIVGLVRSFQEGNFQKRIRFSGNDEFVQIADSFNVM 348 C + + V+ VV+R R++S+IV ++ SFQEG F KR+ F GNDEF I+ + N M Sbjct: 288 CLICIGIFFVVSIVVSRYFSRRVSKIVSVLDSFQEGEFHKRVSFKGNDEFTHISSALNDM 347 Query: 349 ATNIQELINSVYVQGIQKKQAELEALQAQINPHFLYNTLSTISSLANLGEIEKVTGMVQG 408 +NI +LIN VY+ +QKK+AELE+L AQINPHFLYNTLS+IS LA G ++K+ MV Sbjct: 348 GSNIGKLINEVYLADLQKKEAELESLHAQINPHFLYNTLSSISRLARFGMLDKLQRMVMD 407 Query: 409 LSRFYRLTLNQGNVYIELEKELEQVATYLDIQRVKYADAFTVYVDVEEEILHMQVIKLVL 468 L++FYRL+LN G I ++ ELEQ Y+DIQ++KY D V D E E++ + +KL+L Sbjct: 408 LAKFYRLSLNDGRNIISVKNELEQAQAYVDIQKIKYDDRMQVTYDFEPEVVRYETVKLIL 467 Query: 469 QPFVENVFKHAWFGETIAIRLTGRRVGDNIELKVIDNGIGMRPEDIKRMMQGPS-QAGGY 527 QPF+ENV +HAW G+ I IR+T R + D +E K+IDNG+G P + G GY Sbjct: 468 QPFIENVLEHAWTGDYIHIRITARLLEDALEFKIIDNGVGFPPGRVLDNTGGQDLTNAGY 527 Query: 528 GVKNVNERIKLRYGDDYGVTIASFFGAGTTVRLLLP 563 G++NV++RIKL YG +YGVT+ S G GTTVR+++P Sbjct: 528 GIRNVDQRIKLHYGSEYGVTLFSRAGIGTTVRIVIP 563 >B3K7P4.1 B3K7P4_9BACI Histidine kinase internal region Length = 606 Score = 346 bits (888), Expect = 4e-93, Method: Compositional matrix adjust. Identities = 199/587 (33%), Positives = 336/587 (57%), Gaps = 24/587 (4%) Query: 6 KYMPFTYKMMIPYLLLVLLTDVTIGYISYSMLTDSRTEMAESNIRTGMEQARNNIRYQMD 65 +Y+P K+M+ Y+L +L+ Y+S+SM S + NI+ + Q ++N+ Y+M+ Sbjct: 12 RYVPIGLKLMLSYILFILILVAVNFYVSHSMYDASMRKQTRLNIQGTLLQIKDNVTYKMN 71 Query: 66 EIQRMSDNLFGSQPFQRALELKGTPFEIYLAMLDEIVPQITAPLQLFGNKIRFMLYTPNS 125 +I + S L+ ++ +L E Y M I+P++ + + G +R +Y N Sbjct: 72 DIVQTSATLYDNRTLVLSLRSFEEGVEGYNRMNQVIIPKLESASKAIGLNLRMSVYFHNE 131 Query: 126 QLN---IVSGDNLNEPIYDSDYYILPLKDIADSGWYQSLKDSKRDN--LWLQIDTDQKLD 180 +N V D+ + I + I D+ WY+ + + + LW Q++ D++ Sbjct: 132 SVNERYKVWRDDSTRDFNEQTADIYHMGRIVDTAWYRDIPAEQYNETMLWKQVEEDERDG 191 Query: 181 NLSHVRRLVNFSDYKTV--IGYVRITVSLEDLFGGFDTFPVEEGITLRLVEE------TT 232 +S +RR+V+ ++ + +G +R +V +LF + + G L +++ T+ Sbjct: 192 RISLIRRIVDMNNPLAIAEVGIMRFSVRKSELFDSVNFKKLGAGSELIVLDGAGEAVFTS 251 Query: 233 GDILFQRGPAN------YDDAGG----DYLSLHEKIPGSSFVIESLVPDTYLTKDAGRLG 282 G +L + G A+ Y GG +YL++ E++P + I + VP T + ++A R+ Sbjct: 252 GKLLNKGGTASIAGTNRYVSPGGFPDPEYLTIEERLPQLDWKIIAHVPLTIIEQEAVRVR 311 Query: 283 RVIFALCALSFLVMTVIGYVVARLSGRKMSRIVGLVRSFQEGNFQKRIRFSGNDEFVQIA 342 +C L ++ G++++R +++++IV ++ SF+EG+ KR+ G EF QIA Sbjct: 312 TYFITICLLCVALLIGAGFIISRYFSKRINKIVSVLNSFREGDLHKRMPDKGKGEFSQIA 371 Query: 343 DSFNVMATNIQELINSVYVQGIQKKQAELEALQAQINPHFLYNTLSTISSLANLGEIEKV 402 ++ N M + + LIN VY+ IQKK+AELE LQ QINPHFLYNTLS+I+ LA GE EK+ Sbjct: 372 NALNEMGEDFEALINKVYLTQIQKKEAELEMLQTQINPHFLYNTLSSINQLAKFGENEKL 431 Query: 403 TGMVQGLSRFYRLTLNQGNVYIELEKELEQVATYLDIQRVKYADAFTVYVDVEEEILHMQ 462 MV L++FYRLTLN G I + E+EQ YLDIQ+VKY V D++ I + Sbjct: 432 QKMVVELAQFYRLTLNSGKTLIPVAVEVEQANAYLDIQKVKYGQRMEVTFDIDTNIWPYE 491 Query: 463 VIKLVLQPFVENVFKHAWFGETIAIRLTGRRVGDNIELKVIDNGIGMRPEDIKRMMQGPS 522 IKL+LQPF+ENV KHAW G+ I IR++ + GD+I ++ID+G+GM+ E I+ + Sbjct: 492 TIKLILQPFIENVLKHAWSGDRIHIRISVHKEGDDILYRIIDDGLGMKQERIQEIFDPRD 551 Query: 523 QAG-GYGVKNVNERIKLRYGDDYGVTIASFFGAGTTVRLLLPAGMKD 568 + G G++N+++R+KL YG +YGV+I S G GT+V++ +PA ++ Sbjct: 552 NSHTGCGIRNIDQRVKLHYGSEYGVSIFSKVGIGTSVQIRIPARARN 598 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.139 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,346,381,337 Number of extensions: 145646138 Number of successful extensions: 388080 Number of sequences better than 1.0e-05: 2083 Number of HSP's gapped: 384810 Number of HSP's successfully gapped: 2083 Length of query: 578 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 437 Effective length of database: 1,732,333,088 Effective search space: 757029559456 Effective search space used: 757029559456 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)