BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0341.0014.p (457 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A6E7U4.1 A6E7U4_9SPHI Beta-galactosidase 325 4e-87 B5JGG2.1 B5JGG2_9BACT Glycosyl hydrolases family 2, immunoglobul... 320 2e-85 A9AZL4.1 A9AZL4_HERA2 Glycoside hydrolase family 2 sugar binding 314 2e-83 A5FEH7.2 A5FEH7_FLAJ1 Candidate beta-galactosidase; Glycoside hy... 309 3e-82 B1ZXQ8.1 B1ZXQ8_OPITP Glycoside hydrolase family 2 sugar binding 306 3e-81 >A6E7U4.1 A6E7U4_9SPHI Beta-galactosidase Length = 959 Score = 325 bits (834), Expect = 4e-87, Method: Compositional matrix adjust. Identities = 177/404 (43%), Positives = 241/404 (59%), Gaps = 18/404 (4%) Query: 65 WKPVSLPHDWCVEQQYVQDASL--GSRDGSHGYLPGGTGFYRKTFELPPEAADRKWTVTF 122 W+ + LPHDW VEQQ+ AS G + + G+YRK+ +P RK ++ F Sbjct: 83 WRKLDLPHDWAVEQQFDPAASFSHGFKAVGRNFPDASVGWYRKSVFIPAGDLGRKISIAF 142 Query: 123 DGASGLSTVWVNGHLIGEHRGGYIGFSYDLTDVLRYGAEGRNVILVKVEALENEGWWYEG 182 DG S VW+NGH +G GY F YD+TD L YGAE NVI V+V+ EGW+YEG Sbjct: 143 DGVFRNSIVWINGHYLGTEPSGYDSFHYDITDYLNYGAE--NVIAVRVDVTMEEGWFYEG 200 Query: 183 CGIYRHVWLEQTDRLHVAEYGTYITTPEAEKEQALVHISTRICNEYTESRAVSLHTEVYN 242 GIYRHVWL++TD LHVA GT+I++ + + A V T + NE + + + + + Sbjct: 201 AGIYRHVWLDKTDPLHVAANGTFISS-RVQGDTATVTARTVLKNEGLDRASFYIRQNIVD 259 Query: 243 AAGEQVCAKAEQAFA-DWYGETELEQMFRLEHPALWSPETPHLYKAVS-ILKVE------ 294 AAG++V + + A E E L P LW E PHLY+ ++ + K E Sbjct: 260 AAGKEVASGTLENLALGVLQEKEFVMDITLNQPLLWDIEHPHLYQMITTVFKKERGIDEK 319 Query: 295 -GTEVDRYETPFGIRSIRFDPEEGFFLNGEPLLIKGTCNHQDFAGVGVALPDSLIEYKLR 353 G VDRY T FG+R+IRFD ++GFFLNG+P+ IKG+ NHQD AGVGVALPD L +++ Sbjct: 320 AGVMVDRYSTSFGVRTIRFDADKGFFLNGKPIKIKGSNNHQDHAGVGVALPDELQYFRIA 379 Query: 354 LLKEMGSNAYRSAHHPPTPEXXXXXXXXXXXVMDENRKLDSSRSGLDQLKRMLFRDRNHP 413 LKEMGSNAYR +HHPPTPE V+DE+R + + L+ LKRM+ RDRNHP Sbjct: 380 RLKEMGSNAYRCSHHPPTPELLDACDRLGMLVIDEHRLMGITDQHLNYLKRMIIRDRNHP 439 Query: 414 SVIIWNLENEE-VLEGTVTGRRLLKTL---ADTVRXXXSIRRAL 453 S+I W++ NEE +E +V G R+ T+ A TV ++ A+ Sbjct: 440 SIISWSVGNEEWAIENSVVGARIASTMQAFAKTVDSSRAVTAAI 483 >B5JGG2.1 B5JGG2_9BACT Glycosyl hydrolases family 2, immunoglobulin-like beta-sandwich domain Length = 922 Score = 320 bits (820), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 183/463 (39%), Positives = 269/463 (58%), Gaps = 36/463 (7%) Query: 4 AAGRSRSRFDENWSFYKGDIRIPHAV--KAGMTGGITDCGSLQEGEWLD----IAFNDKG 57 AGR R++ ++ W F G HA +A G+ L + + D AF+D+G Sbjct: 24 GAGRERTQINDGWRFALG-----HATDKQADWGHGLGYFSYLAKTGFGDGPAHPAFDDRG 78 Query: 58 MGHQQLEWKPVSLPHDWCVEQQYVQDASLGSRDGSHGYLPGGTGF-------YRKTFELP 110 W+ + LPHDW VEQ + ++AS SHG+ G GF YR++F +P Sbjct: 79 -------WRKIDLPHDWAVEQGFSEEASY-----SHGFKTVGPGFPENSVGWYRRSFSIP 126 Query: 111 PEAADRKWTVTFDGASGLSTVWVNGHLIGEHRGGYIGFSYDLTDVLRYGAEGRNVILVKV 170 ++ + FDG + V+VNG +G+ G++ SYD+++ L YG G NV++V+ Sbjct: 127 ESDLGKRIRIEFDGIYRDAAVFVNGFFVGQEPSGFVSQSYDVSEYLNYG--GDNVVVVRA 184 Query: 171 EALENEGWWYEGCGIYRHVWLEQTDRLHVAEYGTYITTPEAEKEQALVHISTRICNEYTE 230 +A EGW+YEG GIYRH +L +TD LHV YG +++T + K+ ALV + T++ NE Sbjct: 185 DAFMEEGWYYEGAGIYRHAYLLKTDPLHVDRYGVFVST-KKNKKGALVSVKTKMVNEGRA 243 Query: 231 SRAVSLHTEVYNAAGEQVCAKAEQAFADWYGE-TELEQMFRLEHPALWSPETPHLYKAVS 289 S+ L + +A G+ V A + GE T+ + +L +P++W +TP+LY V+ Sbjct: 244 SKRFQLSQSIVDADGQVVAKGAPVSVELEAGESTKRNEGIQLRNPSVWDLDTPYLYTLVT 303 Query: 290 ILKVE-GTEVDRYETPFGIRSIRFDPEEGFFLNGEPLLIKGTCNHQDFAGVGVALPDSLI 348 L+ E G E+DRYET FG+R IRFDP+EGFFLNG + +KGT NH D AG+G ALPD++ Sbjct: 304 SLEGENGVELDRYETRFGVREIRFDPDEGFFLNGRSVKLKGTNNHHDHAGIGAALPDAMQ 363 Query: 349 EYKLRLLKEMGSNAYRSAHHPPTPEXXXXXXXXXXXVMDENRKLDSSRSGLDQLKRMLFR 408 EY++RLLKEMGSNAYR +HH +P V+DENR + + L QL+ ++ R Sbjct: 364 EYRIRLLKEMGSNAYRVSHHHASPALLDACDRLGMLVIDENRLMGINDYHLGQLEHLILR 423 Query: 409 DRNHPSVIIWNLENEE-VLEGTVTGRRLLKTLADTVRXXXSIR 450 RNHPSVI+W++ NEE +EG V G R+ + D + R Sbjct: 424 GRNHPSVILWSVGNEEWGIEGNVKGARIATYMQDFAKRLDPTR 466 >A9AZL4.1 A9AZL4_HERA2 Glycoside hydrolase family 2 sugar binding Length = 925 Score = 314 bits (804), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 176/454 (38%), Positives = 252/454 (55%), Gaps = 25/454 (5%) Query: 7 RSRSRFDENWSFYKGDIRIPHAVKAGMTGGITDCGSLQEGEWLDIA-FNDKGMGHQQLEW 65 R R FD+ W F G P T + G+ A F+D+ W Sbjct: 7 RERILFDQGWRFALGHAFDPAQDFQLDTSHFSFLAKAGYGDGAASAKFDDRA-------W 59 Query: 66 KPVSLPHDWCVEQQYVQDASLGSRDGSHGY------LPGGT-GFYRKTFELPPEAADRKW 118 + + LPHDWCVE + Q + SHGY P + G+YRKTF +P + R+ Sbjct: 60 RLLDLPHDWCVELPFDQRGT-----HSHGYKAIGRKFPANSVGWYRKTFAIPADDLGRRI 114 Query: 119 TVTFDGASGLSTVWVNGHLIGEHRGGYIGFSYDLTDVLRYGAEGRNVILVKVEALENEGW 178 ++ FDG S VWVNG +G GY FSYD++D L YG G+NV++V+ +A EGW Sbjct: 115 SLEFDGVHRDSKVWVNGFYLGNEPSGYTSFSYDISDYLNYG--GQNVVVVRADATTEEGW 172 Query: 179 WYEGCGIYRHVWLEQTDRLHVAEYGTYITTPEAEKEQALVHISTRICNEYTESRAVSLHT 238 +YEG GIYRHVWL +T ++HVA YGT++T+ E + A + I T + NE SL Sbjct: 173 FYEGAGIYRHVWLSKTAQVHVARYGTFVTS-EIHEASATLTIQTTVINESQHPIEFSLLE 231 Query: 239 EVYNAAGEQVCAKAEQAFADWYGET-ELEQMFRLEHPALWSPETPHLYKAVSILKVEGTE 297 + + A V + G++ E L +P LW +PHLY+ + + + Sbjct: 232 TISDPAANNVLQAQSANYQLAAGQSAEFSHQHTLNNPQLWDLASPHLYQLTTTVLLGEQA 291 Query: 298 VDRYETPFGIRSIRFDPEEGFFLNGEPLLIKGTCNHQDFAGVGVALPDSLIEYKLRLLKE 357 VD Y+T FGIRSIRFDP++GFFLNG + + G+ HQD AGVG A+PDSL EY+++ L+E Sbjct: 292 VDSYQTTFGIRSIRFDPDQGFFLNGRSVKLVGSNQHQDHAGVGTAIPDSLQEYRIKRLQE 351 Query: 358 MGSNAYRSAHHPPTPEXXXXXXXXXXXVMDENRKLDSSRSGLDQLKRMLFRDRNHPSVII 417 NA R++H+PPTPE V++ENR + ++ L +++++ RDRNHPSVI+ Sbjct: 352 FNHNAIRTSHNPPTPEFLAACDRLGMLVLNENRLMGTNAEHLRHVEQLIKRDRNHPSVIL 411 Query: 418 WNLENEE-VLEGTVTGRRLLKTLADTVRXXXSIR 450 W+L NEE +EGT+ G R+ T+ + R R Sbjct: 412 WSLGNEEWAIEGTIIGARISSTMQNFARQFDHTR 445 >A5FEH7.2 A5FEH7_FLAJ1 Candidate beta-galactosidase; Glycoside hydrolase family 2 EC=3.2.1.23 Length = 939 Score = 309 bits (792), Expect = 3e-82, Method: Compositional matrix adjust. Identities = 158/395 (40%), Positives = 234/395 (59%), Gaps = 17/395 (4%) Query: 65 WKPVSLPHDWCVEQQYVQDASLGSRDGSHGYLPGGTGF-------YRKTFELPPEAADRK 117 W+ + LPHDW VEQ++ + S SHG+ G GF YRK +P + Sbjct: 81 WRKLDLPHDWAVEQEFSESGSF-----SHGFKTSGKGFPEKSIGWYRKKITIPETDKGKI 135 Query: 118 WTVTFDGASGLSTVWVNGHLIGEHRGGYIGFSYDLTDVLRYGAEGRNVILVKVEALENEG 177 ++ FDG S V+ NG+ +G + GY GF YD++ + YG G N I+V+ +A EG Sbjct: 136 ISIKFDGVFRNSKVFFNGYYLGTEQSGYNGFEYDVSAYVNYG--GENTIVVRADASMEEG 193 Query: 178 WWYEGCGIYRHVWLEQTDRLHVAEYGTYITTPEAEKEQALVHISTRICNEYTESRAVSLH 237 W+YEG GIYRHV+L++T+ +HVA GTYIT+ E A + I N+ +V + Sbjct: 194 WFYEGAGIYRHVYLQKTNPIHVAANGTYITS-EITNTTAEITAEVSIENKGNYKGSVEII 252 Query: 238 TEVYNAAGEQVCAKAEQAFA-DWYGETELEQMFRLEHPALWSPETPHLYKAVSILKVEGT 296 V++A+ +Q+ +E A ++Y + ++ +P LW ++P+LY+ V+ +K Sbjct: 253 QTVFDASNQQIAGVSENVNAPEFYKTDKYTSKLQVNNPLLWDIDSPNLYRLVTQIKQNEK 312 Query: 297 EVDRYETPFGIRSIRFDPEEGFFLNGEPLLIKGTCNHQDFAGVGVALPDSLIEYKLRLLK 356 +D YET FGIR+I+FD E+GFFLNG+P+ +KGT NHQD AG+G ALPD + Y+++ LK Sbjct: 313 IIDNYETSFGIRTIKFDSEKGFFLNGKPVKLKGTNNHQDHAGIGTALPDEIQYYRIKKLK 372 Query: 357 EMGSNAYRSAHHPPTPEXXXXXXXXXXXVMDENRKLDSSRSGLDQLKRMLFRDRNHPSVI 416 EMGSNAYR +HHPPTPE V++E R + + L+ LKRM+ RDRNHPS+ Sbjct: 373 EMGSNAYRCSHHPPTPELLKACDELGMLVINETRLMGINDYHLNDLKRMMERDRNHPSIF 432 Query: 417 IWNLENEE-VLEGTVTGRRLLKTLADTVRXXXSIR 450 W++ NEE +EG + G R+ + D + R Sbjct: 433 CWSVGNEEWNIEGNIVGERVTNVMQDFAKSIDPTR 467 >B1ZXQ8.1 B1ZXQ8_OPITP Glycoside hydrolase family 2 sugar binding Length = 932 Score = 306 bits (784), Expect = 3e-81, Method: Compositional matrix adjust. Identities = 183/456 (40%), Positives = 254/456 (55%), Gaps = 25/456 (5%) Query: 6 GRSRSRFDENWSFYKGDIRIPHAVKAGMTGGITDCGSLQEGE-WLDIAFNDKGMGHQQLE 64 GR R D W F G P TG + G+ AF+D+ Sbjct: 40 GRERILLDAGWRFALGHATDPARDFGHGTGYFSYLAKTGFGDGAASPAFDDR-------T 92 Query: 65 WKPVSLPHDWCVEQQYVQDASLGSRDGSHGYLPGG-------TGFYRKTFELPPEAADRK 117 W+ + LPHDW VE + S SHGY G G+YR++F +P R+ Sbjct: 93 WRQLDLPHDWAVEVPFDPRGS-----HSHGYKAVGPRFPERSVGWYRRSFHVPESDLGRR 147 Query: 118 WTVTFDGASGLSTVWVNGHLIGEHRGGYIGFSYDLTDVLRYGAEGRNVILVKVEALENEG 177 + FDG + V+VNG +GE GY+G SYD+++ L YG G NVI V+V+A EG Sbjct: 148 IRLDFDGVFRAARVFVNGFFVGEEPSGYLGASYDVSEYLNYG--GDNVIAVRVDASMEEG 205 Query: 178 WWYEGCGIYRHVWLEQTDRLHVAEYGTYITTPEAEKEQALVHISTRICNEYTESRAVSLH 237 W+YEG GIYRHVWL +T LHVA GT++ T + + A V I TR+ N +L Sbjct: 206 WFYEGAGIYRHVWLVKTAPLHVALDGTWVRT-DVSPKFATVTIETRVNNAGRAPADYTLE 264 Query: 238 TEVYNAAGEQVCAKAEQAFADWYGETELEQ-MFRLEHPALWSPETPHLYKAVSILKVEGT 296 E++ G+ + + A A G + + R+ P LWS E+P +++ V+ ++ Sbjct: 265 QEIFGPDGKSLARSSAAAPAVAPGGVGVHRDSLRVNAPQLWSLESPTMHRVVTTIRQANA 324 Query: 297 EVDRYETPFGIRSIRFDPEEGFFLNGEPLLIKGTCNHQDFAGVGVALPDSLIEYKLRLLK 356 VDRYETPFGIR+IRFDP GFFLNG+ +++KGT NHQD AGVG A+PD+L E+++R LK Sbjct: 325 IVDRYETPFGIRTIRFDPNRGFFLNGQRVVLKGTNNHQDHAGVGAAIPDTLQEFRIRRLK 384 Query: 357 EMGSNAYRSAHHPPTPEXXXXXXXXXXXVMDENRKLDSSRSGLDQLKRMLFRDRNHPSVI 416 EMGSNAYR++H+P TPE V++ENR + + L QL+RM+ R RNHPS+I Sbjct: 385 EMGSNAYRASHNPSTPELLDACDRLGMLVIEENRLMGINPYHLGQLERMIRRARNHPSII 444 Query: 417 IWNLENEE-VLEGTVTGRRLLKTLADTVRXXXSIRR 451 +W+L NEE +EG + G R+ + D RR Sbjct: 445 LWSLGNEEWGIEGNIKGARITVPMQDFAHRLDPTRR 480 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.136 0.425 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,958,742,173 Number of extensions: 131142992 Number of successful extensions: 241958 Number of sequences better than 1.0e-05: 1459 Number of HSP's gapped: 238493 Number of HSP's successfully gapped: 1492 Length of query: 457 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 318 Effective length of database: 1,751,175,118 Effective search space: 556873687524 Effective search space used: 556873687524 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 133 (55.8 bits)