BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0341.0010.p (187 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A4J8W4.1 A4J8W4_DESRM Transcriptional regulator, TetR family 127 5e-28 Q1R1D8.1 Q1R1D8_CHRSD Transcriptional regulator, TetR family 114 4e-24 Q5WCR1.1 Q5WCR1_BACSK TetR family transcriptional regulator 109 1e-22 B3KAF9.1 B3KAF9_9BACI Regulatory protein TetR 105 2e-21 Q2B541.1 Q2B541_9BACI Putative uncharacterized protein 98 3e-19 >A4J8W4.1 A4J8W4_DESRM Transcriptional regulator, TetR family Length = 195 Score = 127 bits (319), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 67/186 (36%), Positives = 110/186 (59%), Gaps = 4/186 (2%) Query: 3 AALSEFAEKGFEGASLAGIAQLVGIKKQSIATYFPKKEDLFIAAFQEMARHYIEFLDQLY 62 +LS FA+KG+EG SLA IAQ VGI+K SI ++F KE LF++ F+++ + +E Sbjct: 8 VSLSLFAQKGYEGTSLANIAQGVGIRKSSIYSHFEGKEHLFLSVFEDVQKEELEAFINFC 67 Query: 63 KEILGTPVEARLREIVYRTYYYRV--EYPVLTAFYKRSVQFPAPFFQEMLEQQISMMEQR 120 ++I + +L I YY + V F+KR++ FP F +E L+++I E+ Sbjct: 68 QDIKDDSAKGKLYSIF--KYYGEMYENNNVEVVFWKRNILFPPEFLKEKLQEKIIFYEKT 125 Query: 121 SAAFYRAVFEEGMNSGEIRRQHTESLLSAYYCLQDGIAMQMFFYNQEEFGRRLKDIWEIF 180 + A+F +G+ +GEI+ ++ E LL + CL DG+ M+ +Y ++ + RL+ +W F Sbjct: 126 MSEMVTAIFNKGIINGEIQPRNVEDLLGTFICLIDGMFMESHYYTRQHYQVRLEAVWHTF 185 Query: 181 WAGIKQ 186 WAGIK Sbjct: 186 WAGIKN 191 >Q1R1D8.1 Q1R1D8_CHRSD Transcriptional regulator, TetR family Length = 214 Score = 114 bits (285), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 64/185 (34%), Positives = 96/185 (51%), Gaps = 3/185 (1%) Query: 2 QAALSEFAEKGFEGASLAGIAQLVGIKKQSIATYFPKKEDLFIAAFQEMARHYIEFLDQL 61 Q L+ FA G+EG SLA IA GIKK SI +FP K LF+A F+++ + +D Sbjct: 31 QTGLALFARHGYEGTSLAHIAAETGIKKPSIYNHFPNKAALFLAIFEDVESGIVTLIDDS 90 Query: 62 YKEILGTPVEARLREIVYRT-YYYRVEYPVLTAFYKRSVQFPAPFFQEMLEQQISMMEQR 120 G P AR ++ + R E+ + FYKR + FP + + E R Sbjct: 91 LTHSRGLPTRARFERLIRACATFIRREHQGV--FYKRYLLFPPTDVAADVAAISNDNENR 148 Query: 121 SAAFYRAVFEEGMNSGEIRRQHTESLLSAYYCLQDGIAMQMFFYNQEEFGRRLKDIWEIF 180 A +F EG SGE+R ++A+YCL DG+ + F+Y+ + F +RL+ W +F Sbjct: 149 INAHLHTLFTEGRQSGELRALPEAQFIAAFYCLMDGLFAENFYYDADTFEQRLEGAWAVF 208 Query: 181 WAGIK 185 WAG++ Sbjct: 209 WAGLE 213 >Q5WCR1.1 Q5WCR1_BACSK TetR family transcriptional regulator Length = 199 Score = 109 bits (272), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 64/187 (34%), Positives = 99/187 (52%), Gaps = 4/187 (2%) Query: 2 QAALSEFAEKGFEGASLAGIAQLVGIKKQSIATYFPKKEDLFIAAFQEM-ARHYIEFLDQ 60 QAAL FA+ G+EG SLA +A VGIK SI +F K+DLF+ + E+ H + + Q Sbjct: 10 QAALVAFAKGGYEGMSLAEVASAVGIKPPSIYAFFKSKQDLFMTIYHELLDEHAAQLVQQ 69 Query: 61 L-YKEILGTPVEARLREIVYRTYYYRVEYPVLTAFYKRSVQFPAPFFQEMLEQQISMMEQ 119 EI G+ E RLR++V Y + T F R FP F ++ + + + EQ Sbjct: 70 TNVMEIEGS--EQRLRKVVEAMLDYHLREQTKTEFLTRVNLFPPDFLKDEMRSRFAANEQ 127 Query: 120 RSAAFYRAVFEEGMNSGEIRRQHTESLLSAYYCLQDGIAMQMFFYNQEEFGRRLKDIWEI 179 + + A+F EG+ G+I+ + L+ ++ CL DG+ +Q F+YN+E W+ Sbjct: 128 QIRSSLVAIFSEGIEQGDIQSEPLHELVDSFLCLLDGLFLQTFYYNKETLETSFFHAWKF 187 Query: 180 FWAGIKQ 186 +W GI Sbjct: 188 YWQGISN 194 >B3KAF9.1 B3KAF9_9BACI Regulatory protein TetR Length = 193 Score = 105 bits (262), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 56/184 (30%), Positives = 100/184 (54%), Gaps = 1/184 (0%) Query: 2 QAALSEFAEKGFEGASLAGIAQLVGIKKQSIATYFPKKEDLFIAAFQEMARHYIEFLDQL 61 +AAL F +KG++G +L+ IA+ VG+K +I +F KEDLF+ F+E Y E++ + Sbjct: 8 EAALRLFGQKGYDGTALSEIAKEVGVKTPAIYAFFESKEDLFMTVFEESMSAYNEYIQAM 67 Query: 62 YKEILGTPVEARLREIVYRTYYYRVEYPVLTAFYKRSVQFPAPFFQEMLEQQISMMEQRS 121 + G E +L ++ R Y + + L F R + FP F + +++ + Sbjct: 68 AETSKGMSTEKKLHALLLRQYDFHRDKQELAVFAFRYLVFPPDFLMDRMQEAFGRFDTLL 127 Query: 122 AAFYRAVFEEGMNSGEIRRQHTESLLSAYYCLQDGIAMQMFFYNQEE-FGRRLKDIWEIF 180 ++ + +EG++ GE+ E+L+ +Y L DG+ MQ ++Y E F R+LK +E+F Sbjct: 128 SSIIGEIMQEGLDRGELAIVPMETLVDSYLTLMDGLGMQYYYYKSPELFERKLKHAFEMF 187 Query: 181 WAGI 184 W + Sbjct: 188 WRSV 191 >Q2B541.1 Q2B541_9BACI Putative uncharacterized protein Length = 195 Score = 97.8 bits (242), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 63/190 (33%), Positives = 99/190 (52%), Gaps = 15/190 (7%) Query: 2 QAALSEFAEKGFEGASLAGIAQLVGIKKQSIATYFPKKEDLFIAAFQEMARHYIEFL--- 58 QAAL FAEKG+EG L+ IA+ VGIK S+ +FP KE+LF++ F++ +E L Sbjct: 8 QAALKLFAEKGYEGTPLSAIAKAVGIKTPSLYAHFPSKEELFLSVFRDTVS--LELLTIK 65 Query: 59 ----DQLYKEILGTPVEARLREIVYRTYYYRVEYPVLTAFYKRSVQFPAPFFQEMLEQQI 114 DQ L T ++ I R E + F+KR++ FP L+++ Sbjct: 66 EAMDDQSSDNALDT-----IKAIFDALTELREENENIQ-FFKRAIFFPPADLGPKLKEEF 119 Query: 115 SMMEQRSAAFYRAVFEEGMNSGEIRRQHTESLLSAYYCLQDGIAMQMFFYNQEEFGRRLK 174 E+ S + +FE G + + +A+YCL DG+ ++ +Y+QEE+ +R + Sbjct: 120 FEYEKHSTDMLQGLFEHGKKESMFTAVGSGEMAAAFYCLIDGLLVEQHYYSQEEYNKRRE 179 Query: 175 DIWEIFWAGI 184 W+IF AGI Sbjct: 180 SAWKIFLAGI 189 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.325 0.138 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,018,909,547 Number of extensions: 37075195 Number of successful extensions: 142374 Number of sequences better than 1.0e-05: 145 Number of HSP's gapped: 142854 Number of HSP's successfully gapped: 145 Length of query: 187 Length of database: 3,060,696,203 Length adjustment: 128 Effective length of query: 59 Effective length of database: 1,854,806,283 Effective search space: 109433570697 Effective search space used: 109433570697 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 127 (53.5 bits)