BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0340.0033.p (185 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C2QKX9.1 C2QKX9_BACCE Transcriptional regulator 160 5e-38 C2ZYE1.1 C2ZYE1_BACCE Transcriptional regulator 159 1e-37 C2ZH15.1 C2ZH15_BACCE Transcriptional regulator 159 1e-37 Q8CUW2.1 Q8CUW2_OCEIH Transcriptional regulator 147 4e-34 Q1AWE4.1 Q1AWE4_RUBXD Transcriptional regulator, TetR family 142 9e-33 >C2QKX9.1 C2QKX9_BACCE Transcriptional regulator Length = 187 Score = 160 bits (405), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 78/174 (44%), Positives = 121/174 (69%), Gaps = 2/174 (1%) Query: 11 KRMLIILAAIEVMRELGGEQLTLELVAKRAGVSKGGLLYHFPGKEALVNGVVEALTNSFE 70 K+ I++AA E+++E G +LTLE VA+RAGVSKGGLLYHFP KEAL+ G+VE TN++ Sbjct: 13 KKKNILIAASEIVKEEGVVKLTLEAVAQRAGVSKGGLLYHFPSKEALIKGMVEDWTNNYF 72 Query: 71 ADLEKRIVADPISS-GRWSRAYIESTFDEAGVGNDVGTVLASALFLNPESLNGIRHAYAE 129 + + D ++ G+W+RAY++STF + N++ + L +A+F+NP+ L+ R Y Sbjct: 73 ECINTLVNNDDDNAIGKWNRAYLKSTFSDLE-NNNLNSALMAAMFINPDLLDEFRQRYDI 131 Query: 130 WQRNIENDGLDPVQTTLARLAADGLWFAEMFGLAPPGKELKQRVLEALLQLTKE 183 + DG+DPV+ T+ RL+ DGLWF+E+FG+AP +ELK +V + L+ + +E Sbjct: 132 LHTKLITDGIDPVKITITRLSIDGLWFSEIFGMAPLNEELKTQVFDELINMIQE 185 >C2ZYE1.1 C2ZYE1_BACCE Transcriptional regulator Length = 187 Score = 159 bits (401), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 77/174 (44%), Positives = 120/174 (68%), Gaps = 2/174 (1%) Query: 11 KRMLIILAAIEVMRELGGEQLTLELVAKRAGVSKGGLLYHFPGKEALVNGVVEALTNSFE 70 K+ I++AA E+++E G +LTLE VA+RAGVSKGGLLYHFP KEAL+ G+VE TN++ Sbjct: 13 KKKNILIAASEIVKEEGVVKLTLEAVAQRAGVSKGGLLYHFPSKEALIKGMVEDWTNNYF 72 Query: 71 ADLEKRIVADPISS-GRWSRAYIESTFDEAGVGNDVGTVLASALFLNPESLNGIRHAYAE 129 + + D ++ G+W+RAY++STF + N++ + L + +F+NP+ L+ R Y Sbjct: 73 ECINTLVNNDDDNAIGKWNRAYLKSTFSDLE-NNNLNSALMATMFINPDLLDEFRQRYDI 131 Query: 130 WQRNIENDGLDPVQTTLARLAADGLWFAEMFGLAPPGKELKQRVLEALLQLTKE 183 + DG+DPV+ T+ RL+ DGLWF+E+FG+AP +ELK +V + L+ + +E Sbjct: 132 LHTKLITDGIDPVKITITRLSIDGLWFSEIFGMAPLNEELKTQVFDELINMIQE 185 >C2ZH15.1 C2ZH15_BACCE Transcriptional regulator Length = 187 Score = 159 bits (401), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 77/174 (44%), Positives = 120/174 (68%), Gaps = 2/174 (1%) Query: 11 KRMLIILAAIEVMRELGGEQLTLELVAKRAGVSKGGLLYHFPGKEALVNGVVEALTNSFE 70 K+ I++AA E+++E G +LTLE VA+RAGVSKGGLLYHFP KEAL+ G+VE TN++ Sbjct: 13 KKKNILIAASEIVKEEGVVKLTLEAVAQRAGVSKGGLLYHFPSKEALIKGMVEDWTNNYF 72 Query: 71 ADLEKRIVADPISS-GRWSRAYIESTFDEAGVGNDVGTVLASALFLNPESLNGIRHAYAE 129 + + D ++ G+W+RAY++STF + N++ + L + +F+NP+ L+ R Y Sbjct: 73 ECINTLVNNDDDNAIGKWNRAYLKSTFSDLE-NNNLNSALMATMFINPDLLDEFRQRYDI 131 Query: 130 WQRNIENDGLDPVQTTLARLAADGLWFAEMFGLAPPGKELKQRVLEALLQLTKE 183 + DG+DPV+ T+ RL+ DGLWF+E+FG+AP +ELK +V + L+ + +E Sbjct: 132 LHTKLITDGIDPVKITITRLSIDGLWFSEIFGMAPLNEELKTQVFDELINMIQE 185 >Q8CUW2.1 Q8CUW2_OCEIH Transcriptional regulator Length = 191 Score = 147 bits (371), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 73/170 (42%), Positives = 107/170 (62%) Query: 8 KIPKRMLIILAAIEVMRELGGEQLTLELVAKRAGVSKGGLLYHFPGKEALVNGVVEALTN 67 K +++ I+ AA ++ E G LTLE VAK AG+SKGGLLYHFP KEALV G+VE L Sbjct: 3 KQSRKITILNAASGIVSEKGIFNLTLEAVAKEAGISKGGLLYHFPSKEALVKGMVEHLAQ 62 Query: 68 SFEADLEKRIVADPISSGRWSRAYIESTFDEAGVGNDVGTVLASALFLNPESLNGIRHAY 127 +++ + + DP+ G+W+R+++ TF++ D+ L +A +NP+ + + AY Sbjct: 63 NYQNKISDNVERDPLERGKWTRSFLNVTFNQGYPNKDMHAGLLAAKAVNPKLMAPLHDAY 122 Query: 128 AEWQRNIENDGLDPVQTTLARLAADGLWFAEMFGLAPPGKELKQRVLEAL 177 +WQ NIENDGLDP+ T+ RLAADG+W AE+ E K+ V + L Sbjct: 123 EKWQGNIENDGLDPIDATIIRLAADGIWLAELLEHYNIDNEKKKEVYKRL 172 >Q1AWE4.1 Q1AWE4_RUBXD Transcriptional regulator, TetR family Length = 203 Score = 142 bits (359), Expect = 9e-33, Method: Compositional matrix adjust. Identities = 87/177 (49%), Positives = 112/177 (63%), Gaps = 5/177 (2%) Query: 12 RMLIILAAIEVMRELGGEQLTLELVAKRAGVSKGGLLYHFPGKEALVNGVVEALTNSFEA 71 R ++LAA + G +LTLE VA AGVSKGGLLYHF GKE L+ +V FE Sbjct: 22 RRRLLLAAERLAGREGVARLTLEAVAAEAGVSKGGLLYHFSGKEELIGAMVMRWVEDFER 81 Query: 72 DLEKRIVADPISSGRWSRAYIESTFD-EAGVGNDVG---TVLASALFLNPESLNGIRHAY 127 D+E R+ + +GRW RAY+ +TF+ EAG G G +VLA+A N E L +R Y Sbjct: 82 DVESRLAREGSRAGRWVRAYVGATFEPEAGSGPAAGEPVSVLAAAA-TNRELLGELRRCY 140 Query: 128 AEWQRNIENDGLDPVQTTLARLAADGLWFAEMFGLAPPGKELKQRVLEALLQLTKEG 184 +WQ +E+DGLDP TL RLAADGLWF+E+FGLAPP L++RV +L+L G Sbjct: 141 RKWQERMEDDGLDPALATLLRLAADGLWFSELFGLAPPSGRLRERVHRRMLELASGG 197 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.316 0.135 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,092,003,542 Number of extensions: 42672643 Number of successful extensions: 124147 Number of sequences better than 1.0e-05: 233 Number of HSP's gapped: 124201 Number of HSP's successfully gapped: 233 Length of query: 185 Length of database: 3,060,696,203 Length adjustment: 127 Effective length of query: 58 Effective length of database: 1,864,227,298 Effective search space: 108125183284 Effective search space used: 108125183284 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 127 (53.5 bits)