BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0340.0011.p (171 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DKV7.1 B1DKV7_9BACL Uroporphyrin-III C-methyltransferase 160 3e-38 C2ZLZ7.1 C2ZLZ7_BACCE Uroporphyrinogen-III C-methyltransferase 149 1e-34 C2Z5D1.1 C2Z5D1_BACCE Uroporphyrinogen-III C-methyltransferase 149 1e-34 C2PTG1.1 C2PTG1_BACCE Uroporphyrinogen-III C-methyltransferase 147 2e-34 A9VLJ4.1 A9VLJ4_BACWK Uroporphyrin-III C-methyltransferase 147 2e-34 >B1DKV7.1 B1DKV7_9BACL Uroporphyrin-III C-methyltransferase Length = 258 Score = 160 bits (406), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 80/146 (54%), Positives = 94/146 (64%) Query: 4 GSVSIVGAGPGDPELLTVKAVRRIQTADVILYDRLVNEEILGCGKPEALRIYCGKAPGRH 63 G V IVGAGPGDPEL+TVKA+RRI ADVILYDRLVNEE+L +P A +YCGKAP H Sbjct: 7 GKVYIVGAGPGDPELITVKAMRRIGLADVILYDRLVNEELLAYARPNAELVYCGKAPNAH 66 Query: 64 SMPQEGIEKLMIKYAAAGNQVVRLKGGDPYMFXXXXXXXXXXXXXXXXXXVIPGITXXXX 123 +MPQE I ++ YA G VVRLKGGDP++F ++PG+T Sbjct: 67 AMPQEEINAALVSYAKQGKTVVRLKGGDPFVFGRGGEEALELAEHGIEWEIVPGVTSAIG 126 Query: 124 XXXXXXXPLTHRGLAASFAIVTGSRC 149 PLTHRG AASFA VTG+RC Sbjct: 127 AAASAAIPLTHRGKAASFACVTGNRC 152 >C2ZLZ7.1 C2ZLZ7_BACCE Uroporphyrinogen-III C-methyltransferase Length = 259 Score = 149 bits (375), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 79/167 (47%), Positives = 97/167 (58%) Query: 2 IQGSVSIVGAGPGDPELLTVKAVRRIQTADVILYDRLVNEEILGCGKPEALRIYCGKAPG 61 + G V IVGAGPGDP+L+TVK +R I+ ADVILYDRLVN+E+L KPEA IYCGK P Sbjct: 1 MMGKVYIVGAGPGDPDLITVKGLRCIEKADVILYDRLVNKELLSYAKPEADLIYCGKLPN 60 Query: 62 RHSMPQEGIEKLMIKYAAAGNQVVRLKGGDPYMFXXXXXXXXXXXXXXXXXXVIPGITXX 121 H+M QE I +IKYA G V RLKGGDP++F +IPGI+ Sbjct: 61 YHTMKQETINTFLIKYAKKGKVVTRLKGGDPFVFGRGGEEAEALAKQSIPFEIIPGISAG 120 Query: 122 XXXXXXXXXPLTHRGLAASFAIVTGSRCXXXXMIMLHPCTGKGLSTV 168 P+THR +ASFAIVTG R + KG+ T+ Sbjct: 121 IAAPAYAGIPVTHRDASASFAIVTGHRKEDAEEEVKWESLAKGVDTL 167 >C2Z5D1.1 C2Z5D1_BACCE Uroporphyrinogen-III C-methyltransferase Length = 259 Score = 149 bits (375), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 79/167 (47%), Positives = 97/167 (58%) Query: 2 IQGSVSIVGAGPGDPELLTVKAVRRIQTADVILYDRLVNEEILGCGKPEALRIYCGKAPG 61 + G V IVGAGPGDP+L+TVK +R I+ ADVILYDRLVN+E+L KPEA IYCGK P Sbjct: 1 MMGKVYIVGAGPGDPDLITVKGLRCIEKADVILYDRLVNKELLSYAKPEADLIYCGKLPN 60 Query: 62 RHSMPQEGIEKLMIKYAAAGNQVVRLKGGDPYMFXXXXXXXXXXXXXXXXXXVIPGITXX 121 H+M QE I +IKYA G V RLKGGDP++F +IPGI+ Sbjct: 61 YHTMKQETINTFLIKYAKKGKVVTRLKGGDPFVFGRGGEEAEALAKQSIPFEIIPGISAG 120 Query: 122 XXXXXXXXXPLTHRGLAASFAIVTGSRCXXXXMIMLHPCTGKGLSTV 168 P+THR +ASFAIVTG R + KG+ T+ Sbjct: 121 IAAPAYAGIPVTHRDASASFAIVTGHRKEDAEEEVKWESLAKGVDTL 167 >C2PTG1.1 C2PTG1_BACCE Uroporphyrinogen-III C-methyltransferase Length = 258 Score = 147 bits (372), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 78/165 (47%), Positives = 96/165 (58%) Query: 4 GSVSIVGAGPGDPELLTVKAVRRIQTADVILYDRLVNEEILGCGKPEALRIYCGKAPGRH 63 G V IVGAGPGDP+L+TVK +R I+ ADVILYDRLVN+E+L KPEA IYCGK P H Sbjct: 2 GKVYIVGAGPGDPDLITVKGLRCIEKADVILYDRLVNKELLSHAKPEADLIYCGKLPNYH 61 Query: 64 SMPQEGIEKLMIKYAAAGNQVVRLKGGDPYMFXXXXXXXXXXXXXXXXXXVIPGITXXXX 123 +M QE I +IKYA G V RLKGGDP++F +IPGI+ Sbjct: 62 TMKQETINTFLIKYAKKGKVVTRLKGGDPFVFGRGGEEAEALAKQSIPFEIIPGISAGIA 121 Query: 124 XXXXXXXPLTHRGLAASFAIVTGSRCXXXXMIMLHPCTGKGLSTV 168 P+THR +ASFA+VTG R + KG+ T+ Sbjct: 122 APAYAGIPVTHRDASASFAVVTGHRKEGAEEEVKWESLAKGVDTL 166 >A9VLJ4.1 A9VLJ4_BACWK Uroporphyrin-III C-methyltransferase Length = 258 Score = 147 bits (372), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 78/165 (47%), Positives = 96/165 (58%) Query: 4 GSVSIVGAGPGDPELLTVKAVRRIQTADVILYDRLVNEEILGCGKPEALRIYCGKAPGRH 63 G V IVGAGPGDP+L+TVK +R I+ ADVILYDRLVN+E+L KPEA IYCGK P H Sbjct: 2 GKVYIVGAGPGDPDLITVKGLRCIEKADVILYDRLVNKELLSHAKPEADLIYCGKLPNYH 61 Query: 64 SMPQEGIEKLMIKYAAAGNQVVRLKGGDPYMFXXXXXXXXXXXXXXXXXXVIPGITXXXX 123 +M QE I +IKYA G V RLKGGDP++F +IPGI+ Sbjct: 62 TMKQETINTFLIKYAKKGKVVTRLKGGDPFVFGRGGEEAEALAKQSIPFEIIPGISAGIA 121 Query: 124 XXXXXXXPLTHRGLAASFAIVTGSRCXXXXMIMLHPCTGKGLSTV 168 P+THR +ASFA+VTG R + KG+ T+ Sbjct: 122 APAYAGIPVTHRDASASFAVVTGHRKEGAEEEVKWESLAKGVDTL 166 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.323 0.141 0.432 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 862,502,373 Number of extensions: 27486617 Number of successful extensions: 49530 Number of sequences better than 1.0e-05: 2035 Number of HSP's gapped: 47524 Number of HSP's successfully gapped: 2035 Length of query: 171 Length of database: 3,060,696,203 Length adjustment: 126 Effective length of query: 45 Effective length of database: 1,873,648,313 Effective search space: 84314174085 Effective search space used: 84314174085 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 126 (53.1 bits)