BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0335.0006.p (337 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C3GJS5.1 C3GJS5_BACTU 6-aminohexanoate-dimer hydrolase 230 1e-58 C3G3U8.1 C3G3U8_BACTU 6-aminohexanoate-dimer hydrolase 230 1e-58 C2QCQ2.1 C2QCQ2_BACCE 6-aminohexanoate-dimer hydrolase 229 2e-58 C3C3B0.1 C3C3B0_BACTU 6-aminohexanoate-dimer hydrolase 228 8e-58 B7IJH6.1 B7IJH6_BACC2 Beta-lactamase 228 8e-58 >C3GJS5.1 C3GJS5_BACTU 6-aminohexanoate-dimer hydrolase Length = 305 Score = 230 bits (587), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 124/315 (39%), Positives = 186/315 (59%), Gaps = 19/315 (6%) Query: 15 MNQMTLQHAIAPLNLRSCLISTRGELRFEHYRDDRTASGIAKINSCTKSVLSSLICIAMD 74 M+ L++ + + L+ +GEL E+Y+ A+ + KINS TKS++S LI IA+D Sbjct: 1 MDFKQLENKFEKKKVNTFLVYQKGELTTEYYKTPECANNLYKINSITKSIVSILIGIAID 60 Query: 75 QGLLPDPSSSVAEFFPQLRRDKDTRKQEITLEHLLTLSAGFRWSEFGGLNSFPK-MTRSP 133 +G + D + + E+ + +K Q++TL HLLT++ G W EFG FP S Sbjct: 61 KGYINDIHTPITEWIENVSEEK----QDLTLYHLLTMTTGEDWKEFGNGVVFPNDFVESD 116 Query: 134 DWVEYVLEQPLXXXXADAPGTRMEYNSGISQLLSAILVQASGMTTARFAEQYLFGPLGIE 193 +WV+Y+LE+P+ + P T+M YNSG S LLS I+ +A+GM T +FA++Y+F PL I Sbjct: 117 NWVQYILEKPM----IEEPATKMNYNSGSSHLLSYIIQKATGMPTEQFAKKYVFDPLEIT 172 Query: 194 EYQWEADPQGIHTGGFGLQLRPSALLKFGQLYLQQGRWNGAQLISRERLARSVTTAMHAE 253 EY+W+ DPQGIH GGFG++++ LLK G L LQ G W G ++IS + L S +TA+ Sbjct: 173 EYEWQQDPQGIHVGGFGMKMKSKDLLKLGILCLQNGYWQGNEIISSKWLEES-STALFET 231 Query: 254 APRRGGYGWHWWTDSYPHAASDGEPPAAMQFYYARGYAGQFVYVLPEPQTVVVLTQDN-K 312 G YG+HWW + P M Y+A GY GQ++ ++P+ + V V++ K Sbjct: 232 YEHVGAYGYHWWVLN----NERFHIPYCM--YFAMGYGGQYIVIIPQLEVVAVISSHMPK 285 Query: 313 RGKNNPPADVFSEHI 327 RG P +F EHI Sbjct: 286 RGL--VPLKLFIEHI 298 >C3G3U8.1 C3G3U8_BACTU 6-aminohexanoate-dimer hydrolase Length = 305 Score = 230 bits (587), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 124/315 (39%), Positives = 186/315 (59%), Gaps = 19/315 (6%) Query: 15 MNQMTLQHAIAPLNLRSCLISTRGELRFEHYRDDRTASGIAKINSCTKSVLSSLICIAMD 74 M+ L++ + + L+ +GEL E+Y+ A+ + KINS TKS++S LI IA+D Sbjct: 1 MDFKQLENKFEKKKVNTFLVYQKGELTTEYYKTPECANNLYKINSITKSIVSILIGIAID 60 Query: 75 QGLLPDPSSSVAEFFPQLRRDKDTRKQEITLEHLLTLSAGFRWSEFGGLNSFPK-MTRSP 133 +G + D + + E+ + +K Q++TL HLLT++ G W EFG FP S Sbjct: 61 KGYINDIHTPITEWIENVSEEK----QDLTLYHLLTMTTGEDWKEFGNGVVFPNDFVESD 116 Query: 134 DWVEYVLEQPLXXXXADAPGTRMEYNSGISQLLSAILVQASGMTTARFAEQYLFGPLGIE 193 +WV+Y+LE+P+ + P T+M YNSG S LLS I+ +A+GM T +FA++Y+F PL I Sbjct: 117 NWVQYILEKPM----IEEPATKMNYNSGSSHLLSYIIQKATGMPTEQFAKKYVFDPLEIT 172 Query: 194 EYQWEADPQGIHTGGFGLQLRPSALLKFGQLYLQQGRWNGAQLISRERLARSVTTAMHAE 253 EY+W+ DPQGIH GGFG++++ LLK G L LQ G W G ++IS + L S +TA+ Sbjct: 173 EYEWQQDPQGIHVGGFGMKMKSKDLLKLGILCLQNGYWQGNEIISSKWLEES-STALFET 231 Query: 254 APRRGGYGWHWWTDSYPHAASDGEPPAAMQFYYARGYAGQFVYVLPEPQTVVVLTQDN-K 312 G YG+HWW + P M Y+A GY GQ++ ++P+ + V V++ K Sbjct: 232 YEHVGAYGYHWWVLN----NERFHIPYCM--YFAMGYGGQYIVIIPQLEVVAVISSHMPK 285 Query: 313 RGKNNPPADVFSEHI 327 RG P +F EHI Sbjct: 286 RGL--VPLKLFIEHI 298 >C2QCQ2.1 C2QCQ2_BACCE 6-aminohexanoate-dimer hydrolase Length = 323 Score = 229 bits (585), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 124/330 (37%), Positives = 193/330 (58%), Gaps = 26/330 (7%) Query: 7 TSYERMSR-------MNQMTLQHAIAPLNLRSCLISTRGELRFEHYRDDRTASGIAKINS 59 TSY ++S ++ L++ + + L+ +GEL E+Y+ +AS + KINS Sbjct: 4 TSYNKLSNDLIGGKVLDFKQLENKFEKKKVNTFLVYQKGELTNEYYKTIESASNLYKINS 63 Query: 60 CTKSVLSSLICIAMDQGLLPDPSSSVAEFFPQLRRDKDTRKQEITLEHLLTLSAGFRWSE 119 TKS++S LI IA+D+G + D + + ++ + ++K E+T+ HLLT++ G W E Sbjct: 64 ITKSIVSILIGIAIDKGYINDIHTPITKWILNVPKEKS----ELTIYHLLTMTTGEDWKE 119 Query: 120 FGGLNSFPK-MTRSPDWVEYVLEQPLXXXXADAPGTRMEYNSGISQLLSAILVQASGMTT 178 FG FP S +WV+Y+L +P+ + P T+M YNSG S LLS I+ +A+GMTT Sbjct: 120 FGNGVVFPNDFVESENWVQYILAKPI----IEEPATKMNYNSGSSHLLSYIIQKATGMTT 175 Query: 179 ARFAEQYLFGPLGIEEYQWEADPQGIHTGGFGLQLRPSALLKFGQLYLQQGRWNGAQLIS 238 +FA++YLF PL I EY+W+ DPQG+H GGFG++++ LLK G L LQ G W G +++S Sbjct: 176 EQFAKRYLFDPLEITEYEWQQDPQGVHVGGFGMKMKSKDLLKLGILCLQNGYWQGNEIVS 235 Query: 239 RERLARSVTTAMHAEAPRRGGYGWHWWTDSYPHAASDGEPPAAMQFYYARGYAGQFVYVL 298 + L S +TA+ G YG+HWW + P M Y+A GY GQ++ ++ Sbjct: 236 SKWLEES-STALFETYEHVGAYGYHWWVLN----NERFHIPYCM--YFAMGYGGQYIVII 288 Query: 299 PEPQTVVVLTQDN-KRGKNNPPADVFSEHI 327 P+ + V V++ KRG P +F EH+ Sbjct: 289 PQLEVVAVISSHMPKRGL--VPLKLFIEHV 316 >C3C3B0.1 C3C3B0_BACTU 6-aminohexanoate-dimer hydrolase Length = 305 Score = 228 bits (580), Expect = 8e-58, Method: Compositional matrix adjust. Identities = 119/315 (37%), Positives = 185/315 (58%), Gaps = 19/315 (6%) Query: 15 MNQMTLQHAIAPLNLRSCLISTRGELRFEHYRDDRTASGIAKINSCTKSVLSSLICIAMD 74 M+ L++ + + L+ +GEL E+Y+ A+ + KINS TKS++S LI IA+D Sbjct: 1 MDFKQLENKFEKKKVNTFLVYQKGELTTEYYKTPECANNLYKINSITKSIVSILIGIAID 60 Query: 75 QGLLPDPSSSVAEFFPQLRRDKDTRKQEITLEHLLTLSAGFRWSEFGGLNSFPK-MTRSP 133 +G + D + + E+ + +K Q++TL HLLT++ G W EFG FP S Sbjct: 61 KGYINDIHTPITEWIENVSAEK----QDLTLYHLLTMTTGEDWKEFGNGVVFPNDFVESD 116 Query: 134 DWVEYVLEQPLXXXXADAPGTRMEYNSGISQLLSAILVQASGMTTARFAEQYLFGPLGIE 193 +WV+Y+LE+P+ + P T+M YNSG S LLS I+ +A+GM T +FA++Y+F PL I Sbjct: 117 NWVQYILEKPI----IEEPATKMNYNSGSSHLLSYIIQKATGMPTEQFAKKYVFDPLDIT 172 Query: 194 EYQWEADPQGIHTGGFGLQLRPSALLKFGQLYLQQGRWNGAQLISRERLARSVTTAMHAE 253 EY+W+ DPQGIH GGFG++++ LLK G L LQ G W G +++S + L S +TA+ Sbjct: 173 EYEWQQDPQGIHVGGFGMKMKSKDLLKLGILCLQNGYWQGNEIVSSKWLEES-STALFET 231 Query: 254 APRRGGYGWHWWTDSYPHAASDGEPPAAMQFYYARGYAGQFVYVLPEPQTVVVLTQDN-K 312 G YG+HWW ++ Y+A GY GQ++ ++P+ + + V++ K Sbjct: 232 YEHVGAYGYHWW------VLNNKRFHIPYCLYFAMGYGGQYIVIIPQLEAIAVISSHMPK 285 Query: 313 RGKNNPPADVFSEHI 327 RG P +F EH+ Sbjct: 286 RGL--VPLKLFIEHV 298 >B7IJH6.1 B7IJH6_BACC2 Beta-lactamase Length = 305 Score = 228 bits (580), Expect = 8e-58, Method: Compositional matrix adjust. Identities = 121/315 (38%), Positives = 186/315 (59%), Gaps = 19/315 (6%) Query: 15 MNQMTLQHAIAPLNLRSCLISTRGELRFEHYRDDRTASGIAKINSCTKSVLSSLICIAMD 74 M+ L++ + + L+ +GEL E+Y+ A+ + KINS TKS++S LI IA+D Sbjct: 1 MDFKQLENKFEKKKVNTFLVYQKGELTTEYYKTPECANNLYKINSITKSIVSLLIGIAID 60 Query: 75 QGLLPDPSSSVAEFFPQLRRDKDTRKQEITLEHLLTLSAGFRWSEFGGLNSFPK-MTRSP 133 +G + D + + E+ + +K ++TL HLLT++ G W EFG FP S Sbjct: 61 KGYINDIHTPITEWIENVPGEK----HDLTLYHLLTMTTGEDWKEFGNGVVFPNDFVESE 116 Query: 134 DWVEYVLEQPLXXXXADAPGTRMEYNSGISQLLSAILVQASGMTTARFAEQYLFGPLGIE 193 +WV+Y+LE+P+ + P T+M YNSG S LLS I+ +A+GM+T RFA++YLF PL I Sbjct: 117 NWVQYILEKPI----IEKPATKMNYNSGSSHLLSYIIQEATGMSTERFAKKYLFDPLEIN 172 Query: 194 EYQWEADPQGIHTGGFGLQLRPSALLKFGQLYLQQGRWNGAQLISRERLARSVTTAMHAE 253 EY+W+ DPQGI+ GGFG++++ + LLK G+L LQ G WNG +++S + L S + A Sbjct: 173 EYEWQQDPQGIYVGGFGMKMKSTDLLKLGKLCLQNGYWNGKEIVSAQWLEES-SRAQFET 231 Query: 254 APRRGGYGWHWWTDSYPHAASDGEPPAAMQFYYARGYAGQFVYVLPEPQTVVVLTQDN-K 312 G YG+HWW H P Y+A GY GQ++ ++P+ + V +++ K Sbjct: 232 YEHVGAYGYHWWV---LHNERFHIPYC---IYFAMGYGGQYIVIIPQLEVVAIISSHMPK 285 Query: 313 RGKNNPPADVFSEHI 327 RG P +F EH+ Sbjct: 286 RGL--VPLKLFIEHV 298 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.134 0.419 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,076,366,200 Number of extensions: 85093057 Number of successful extensions: 157567 Number of sequences better than 1.0e-05: 623 Number of HSP's gapped: 156222 Number of HSP's successfully gapped: 623 Length of query: 337 Length of database: 3,060,696,203 Length adjustment: 136 Effective length of query: 201 Effective length of database: 1,779,438,163 Effective search space: 357667070763 Effective search space used: 357667070763 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 131 (55.1 bits)