BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0334.0009.p (326 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KDC5.1 B3KDC5_9BACI Aldo/keto reductase 591 e-167 B1DLH5.1 B1DLH5_9BACL Aldo/keto reductase 553 e-156 C4C5T8.1 C4C5T8_9FUSO Predicted oxidoreductase similar to aryl-a... 548 e-154 C0V1B6.1 C0V1B6_9BACT Predicted oxidoreductase similar to aryl-a... 520 e-146 C4LEW3.1 C4LEW3_TOLAT Aldo/keto reductase 518 e-145 >B3KDC5.1 B3KDC5_9BACI Aldo/keto reductase Length = 326 Score = 591 bits (1523), Expect = e-167, Method: Compositional matrix adjust. Identities = 278/326 (85%), Positives = 302/326 (92%) Query: 1 MEIVKLGNTGLDVSRLCLGCMSFGEADRWVHPWVLDEDRSRIIIKQALELGINFFDTANV 60 ME VKLGNTGLDVSR+CLGCM FG A+RWVH WVL+E+ SR IIK+ALELGINFFDTANV Sbjct: 1 MEYVKLGNTGLDVSRICLGCMGFGVAERWVHQWVLNEESSRPIIKKALELGINFFDTANV 60 Query: 61 YSDGTSEEIVGRALKDYAHRDEIVLATKVHFRMHQGPNGAGLSRKAIMSEIDKSLKRLGT 120 YSDGTSEEIVGRALK+YA+RDEIVLATKVHFRMH+GPNG GLSRKAIMSEIDKSLKRLGT Sbjct: 61 YSDGTSEEIVGRALKEYANRDEIVLATKVHFRMHEGPNGMGLSRKAIMSEIDKSLKRLGT 120 Query: 121 DYVDLYQIHRWDYHTPIEETMEALHDVVKAGKARYIGASAMFAWQFLKALHVAEKHGWTR 180 DYVDLYQIHRWDY TPIEETMEALHDVVKAGK RYIGASAM+AWQFLKA H AEK+GWTR Sbjct: 121 DYVDLYQIHRWDYDTPIEETMEALHDVVKAGKVRYIGASAMYAWQFLKAQHTAEKNGWTR 180 Query: 181 FVSMQNHLNLLYREEEREMLPLCKEEKIAVIPYSPLASGRLTRDWSESTHRSETDQVQKS 240 FVSMQNH NL+YREEEREMLPLC+ EKI VIPYSPLASGRLTRDWSE+T RSETD VQKS Sbjct: 181 FVSMQNHYNLIYREEEREMLPLCQSEKIGVIPYSPLASGRLTRDWSETTQRSETDMVQKS 240 Query: 241 KYDATAKTDRLIAEQVAAIAEQRGVPRAQVALAWLLQKEPVTAPIIGATKISHLEDAAAA 300 KYDATA DR+I E++A IA +RG+PR QVALAWLLQKEP+TAPI+GATKISHLEDAAAA Sbjct: 241 KYDATADADRIIVERLAGIANERGIPRVQVALAWLLQKEPITAPIVGATKISHLEDAAAA 300 Query: 301 LSITLTPEEIASLEEPYVPHPVVGAL 326 L++ LTPEE+ASLEEPY+PH VVGAL Sbjct: 301 LTVKLTPEEMASLEEPYIPHRVVGAL 326 >B1DLH5.1 B1DLH5_9BACL Aldo/keto reductase Length = 326 Score = 553 bits (1426), Expect = e-156, Method: Compositional matrix adjust. Identities = 260/326 (79%), Positives = 289/326 (88%) Query: 1 MEIVKLGNTGLDVSRLCLGCMSFGEADRWVHPWVLDEDRSRIIIKQALELGINFFDTANV 60 ME VKLGNTGLDVSRLCLGCMSFGE +RW HPW+LDE+ SR IIK+AL+LGINFFDTAN+ Sbjct: 1 MEYVKLGNTGLDVSRLCLGCMSFGEVERWNHPWILDEENSRPIIKKALDLGINFFDTANI 60 Query: 61 YSDGTSEEIVGRALKDYAHRDEIVLATKVHFRMHQGPNGAGLSRKAIMSEIDKSLKRLGT 120 YS G SEEIVGRALKDYA+RDE+V+A+KV FRM GPNGAGLSRKAIM+EID SLKRLGT Sbjct: 61 YSTGASEEIVGRALKDYANRDEVVIASKVFFRMQPGPNGAGLSRKAIMNEIDNSLKRLGT 120 Query: 121 DYVDLYQIHRWDYHTPIEETMEALHDVVKAGKARYIGASAMFAWQFLKALHVAEKHGWTR 180 DYVDLYQIHRWDY+TPIEETMEALHDVVKAGKARYIGASAM+AWQF KALHVAE++GWTR Sbjct: 121 DYVDLYQIHRWDYNTPIEETMEALHDVVKAGKARYIGASAMYAWQFQKALHVAEQNGWTR 180 Query: 181 FVSMQNHLNLLYREEEREMLPLCKEEKIAVIPYSPLASGRLTRDWSESTHRSETDQVQKS 240 FV+MQNHLNL+YREEEREM+PL KEEKI IPYSPLASGRL RDW THRSETDQ QK Sbjct: 181 FVAMQNHLNLMYREEEREMMPLLKEEKIGAIPYSPLASGRLVRDWDTVTHRSETDQAQKM 240 Query: 241 KYDATAKTDRLIAEQVAAIAEQRGVPRAQVALAWLLQKEPVTAPIIGATKISHLEDAAAA 300 KYDA A+ DR+IAE+VA IAEQRGVPR QVALAWLLQKE VTAPIIG T ++ LE+ + Sbjct: 241 KYDAFAEQDRVIAERVAEIAEQRGVPRVQVALAWLLQKEQVTAPIIGVTSMAQLEETIGS 300 Query: 301 LSITLTPEEIASLEEPYVPHPVVGAL 326 + +TLTP+E+ LEE YVPH VVGAL Sbjct: 301 IELTLTPDEVKYLEEQYVPHRVVGAL 326 >C4C5T8.1 C4C5T8_9FUSO Predicted oxidoreductase similar to aryl-alcohol dehydrogenase Length = 326 Score = 548 bits (1411), Expect = e-154, Method: Compositional matrix adjust. Identities = 255/326 (78%), Positives = 294/326 (90%) Query: 1 MEIVKLGNTGLDVSRLCLGCMSFGEADRWVHPWVLDEDRSRIIIKQALELGINFFDTANV 60 ME +KLGNTG+DVSR CLGCM FG+++ WVH W+L+E+ SR +IK+AL+LGINFFDTANV Sbjct: 1 MEYIKLGNTGMDVSRFCLGCMGFGDSEAWVHKWLLNEEDSRPVIKKALDLGINFFDTANV 60 Query: 61 YSDGTSEEIVGRALKDYAHRDEIVLATKVHFRMHQGPNGAGLSRKAIMSEIDKSLKRLGT 120 YS G SEEI+GRALKDYA+RDE+V+ATKVH +MH GPNG+GLSRKAIMSEIDKSLKRLGT Sbjct: 61 YSLGKSEEILGRALKDYANRDEVVIATKVHGKMHDGPNGSGLSRKAIMSEIDKSLKRLGT 120 Query: 121 DYVDLYQIHRWDYHTPIEETMEALHDVVKAGKARYIGASAMFAWQFLKALHVAEKHGWTR 180 DYVDLY IHRWDY+TPIEETMEALHD+VKAGKARYIGASAM+AWQF KALH AEK+GWTR Sbjct: 121 DYVDLYIIHRWDYNTPIEETMEALHDIVKAGKARYIGASAMYAWQFQKALHTAEKNGWTR 180 Query: 181 FVSMQNHLNLLYREEEREMLPLCKEEKIAVIPYSPLASGRLTRDWSESTHRSETDQVQKS 240 FVSMQNHLNL+YREEEREM+PLCKEEKIA+ PYSPLASGRLTR+ SE+T RSETDQ+ S Sbjct: 181 FVSMQNHLNLIYREEEREMIPLCKEEKIALTPYSPLASGRLTRNLSETTKRSETDQIAVS 240 Query: 241 KYDATAKTDRLIAEQVAAIAEQRGVPRAQVALAWLLQKEPVTAPIIGATKISHLEDAAAA 300 KY +T + DRL+ E++AA+AE+RG+PR VALAWLLQKEPVT PIIGATK+SHLEDA A Sbjct: 241 KYGSTEEADRLVIERLAAVAERRGIPRLHVALAWLLQKEPVTIPIIGATKLSHLEDAVPA 300 Query: 301 LSITLTPEEIASLEEPYVPHPVVGAL 326 LS+ L PEEIA LEEPYVPH V+GA+ Sbjct: 301 LSVKLEPEEIAFLEEPYVPHKVIGAV 326 >C0V1B6.1 C0V1B6_9BACT Predicted oxidoreductase similar to aryl-alcohol dehydrogenase Length = 332 Score = 520 bits (1339), Expect = e-146, Method: Compositional matrix adjust. Identities = 246/325 (75%), Positives = 283/325 (87%), Gaps = 1/325 (0%) Query: 1 MEIVKLGNTGLDVSRLCLGCMSFGEADRWVHPWVLDEDRSRIIIKQALELGINFFDTANV 60 ME +LGNTGL+VSR+CLGCM FG+ DRWVH WVL E+ SR +IKQAL+LGINFFDTANV Sbjct: 1 MEYTRLGNTGLEVSRICLGCMGFGDPDRWVHKWVLREEESRQVIKQALDLGINFFDTANV 60 Query: 61 YSDGTSEEIVGRALKDYAHRDEIVLATKVHFRMHQGPNGAGLSRKAIMSEIDKSLKRLGT 120 YS G SEEI+GRAL+D+A R+E+V+ATKV+ RM GPNGAGLSRKAIM+EID SL+RLGT Sbjct: 61 YSLGVSEEILGRALRDFASRNEVVIATKVYGRMRPGPNGAGLSRKAIMTEIDHSLRRLGT 120 Query: 121 DYVDLYQIHRWDYHTPIEETMEALHDVVKAGKARYIGASAMFAWQFLKALHVAEKHGWTR 180 DYVDLYQIHRWDY TPIEETMEALHD+VKAGK RYIGASAMFAWQF KAL+VAE+HGWTR Sbjct: 121 DYVDLYQIHRWDYDTPIEETMEALHDLVKAGKVRYIGASAMFAWQFQKALYVAERHGWTR 180 Query: 181 FVSMQNHLNLLYREEEREMLPLCKEEKIAVIPYSPLASGRLTRDWS-ESTHRSETDQVQK 239 FVSMQNH+NL+YREEEREMLPLC+EE I VIPYSPLA+GRLTRDWS ES+ R++TD++ K Sbjct: 181 FVSMQNHMNLIYREEEREMLPLCREEGIGVIPYSPLAAGRLTRDWSQESSLRAQTDEIAK 240 Query: 240 SKYDATAKTDRLIAEQVAAIAEQRGVPRAQVALAWLLQKEPVTAPIIGATKISHLEDAAA 299 KYDA A D I E+VA +A + GV RAQVALAWLL K+PV APIIGATK HLE+A Sbjct: 241 GKYDAMADADWQIIERVAEVARRHGVTRAQVALAWLLGKQPVVAPIIGATKPEHLEEAVG 300 Query: 300 ALSITLTPEEIASLEEPYVPHPVVG 324 ALS+ L+PE++A LEEPYVPHPVVG Sbjct: 301 ALSVQLSPEDVAYLEEPYVPHPVVG 325 >C4LEW3.1 C4LEW3_TOLAT Aldo/keto reductase Length = 327 Score = 518 bits (1334), Expect = e-145, Method: Compositional matrix adjust. Identities = 241/325 (74%), Positives = 284/325 (87%), Gaps = 1/325 (0%) Query: 1 MEIVKLGNTGLDVSRLCLGCMSFGEADRWVHPWVLDEDRSRIIIKQALELGINFFDTANV 60 ME VKLGNTGLDVSR+CLGCM FG+ ++WVH WVL E+ SRIIIK+ALELGINFFDTANV Sbjct: 1 MEYVKLGNTGLDVSRICLGCMGFGDPNKWVHSWVLQEEDSRIIIKKALELGINFFDTANV 60 Query: 61 YSDGTSEEIVGRALKDYAHRDEIVLATKVHFRMHQGPNGAGLSRKAIMSEIDKSLKRLGT 120 YS G SEEI+GRA++DYA+RDE+V+ATK+H +MHQGPNG GLSRKAIMSE+DKSLKRL Sbjct: 61 YSLGASEEILGRAIRDYANRDEVVVATKIHGQMHQGPNGKGLSRKAIMSELDKSLKRLEM 120 Query: 121 DYVDLYQIHRWDYHTPIEETMEALHDVVKAGKARYIGASAMFAWQFLKALHVAEKHGWTR 180 DYVDLY IHRWDY+TPIEETM ALHDVVK+GK RYIGASAM+AWQF KA ++AEK+GWTR Sbjct: 121 DYVDLYIIHRWDYNTPIEETMAALHDVVKSGKVRYIGASAMYAWQFHKAQNIAEKNGWTR 180 Query: 181 FVSMQNHLNLLYREEEREMLPLCKEEKIAVIPYSPLASGRLTRDWS-ESTHRSETDQVQK 239 FVSMQNHLNL+YREEEREM+PLC++++IA+ PYSPLASGRLTRDW+ E+T RSE+D++ Sbjct: 181 FVSMQNHLNLIYREEEREMIPLCRDQQIAITPYSPLASGRLTRDWTAEATKRSESDKIAM 240 Query: 240 SKYDATAKTDRLIAEQVAAIAEQRGVPRAQVALAWLLQKEPVTAPIIGATKISHLEDAAA 299 SKYDAT DR + E++A IAE+R VPR +ALAWLLQK+PV APIIGATKISHLE A Sbjct: 241 SKYDATVDADRTVIERLAEIAEKRDVPRTHIALAWLLQKQPVVAPIIGATKISHLETAIG 300 Query: 300 ALSITLTPEEIASLEEPYVPHPVVG 324 +LS+ LT EEI +E PYVPH +VG Sbjct: 301 SLSLKLTAEEIDYMEAPYVPHNIVG 325 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.133 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,924,614,384 Number of extensions: 76159128 Number of successful extensions: 233878 Number of sequences better than 1.0e-05: 7574 Number of HSP's gapped: 218571 Number of HSP's successfully gapped: 7586 Length of query: 326 Length of database: 3,060,696,203 Length adjustment: 136 Effective length of query: 190 Effective length of database: 1,779,438,163 Effective search space: 338093250970 Effective search space used: 338093250970 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 131 (55.1 bits)