BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0334.0007.p (535 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1D4P3.1 B1D4P3_9BACL Two component transcriptional regulator, A... 280 4e-73 B3KJG1.1 B3KJG1_9BACI Response regulator receiver 270 3e-70 C0Z4C7.1 C0Z4C7_BREBN Probable two-component response regulator 270 4e-70 C5EE52.1 C5EE52_9FIRM Two-component response regulator 234 1e-59 B1D7Q5.1 B1D7Q5_9BACL Two component transcriptional regulator, A... 215 9e-54 >B1D4P3.1 B1D4P3_9BACL Two component transcriptional regulator, AraC family Length = 538 Score = 280 bits (715), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 167/499 (33%), Positives = 273/499 (54%), Gaps = 16/499 (3%) Query: 1 MWKLVLIDDDHIILRGLSRNIPWEEYGFEVSASAHDGEEGLDAVERERPHVVITDIRMPF 60 M+ ++L+DD+ ++ G+ IPWEE GF A +G + L+ +ER RPH+V+TDI MPF Sbjct: 1 MYTILLVDDEAVVREGIRERIPWEELGFRCVADCENGVQALEEIERLRPHIVLTDINMPF 60 Query: 61 MDGLQLTEAIKSKFPDVKIILMTSYDEFEFAQKALKLKVFDFVLKPVENDKLLEVALRAA 120 MDGL L+ + ++P+ K++++T YD+FE+AQ+ALKLKV DF+LKPV + + + Sbjct: 61 MDGLALSREVMERYPETKVVILTGYDDFEYAQQALKLKVKDFILKPVTAAEFSAMLHKLR 120 Query: 121 AEWEQER-------ALAKKVLEGVPFLRQRFYENLLRGKYRQEEIDHELAFLELPLKAER 173 E ++E+ L ++ E +P L++RF E + ++EI L + ++ LK Sbjct: 121 LELDEEKREREDLARLQSQLHESMPLLKERFLERMSTMALTEKEIASRLHYFQIQLKGPC 180 Query: 174 YAVLLIIADDYYETGAGNRFGQELLKYCIHNISLEVLDSLGEGVVFELGEDEIAVICTGS 233 Y L I D E G G +ELL++ ++NI+ E++ VVF E+ + + G Sbjct: 181 YLGLAIDTDRLEEQG-GADTDRELLRFAVYNIAQEIISGEPGAVVFRSREERVMAV-LGG 238 Query: 234 ADQQAMERKVMQMAEHIRYNAEVYLKTTVTVGTGPVCSELTGIAQSYHEAKAATDFRHIA 293 ++ ++ K ++AE IR +A +LK TV+VG G TGI ++ A AA D+R + Sbjct: 239 EREELLQEKAQELAERIRQSAVQFLKLTVSVGIGMTVHSYTGIRETCKAAAAALDYRLVL 298 Query: 294 GTNQVLSFRDT-KVKQHVSGHPAVNGGWEADLGMNIRLGFVQEALLVLEHMEKQIQSAPI 352 G N V+S D K + +GHPA ++ +L I+ G E +E + + ++ Sbjct: 299 GDNSVISILDMEKRRSSPAGHPA---QFDRELIAGIKTGTADEVERAIEALIRYNKAELT 355 Query: 353 TLERLRLLGIEIVLVIVNTFQ--SWSEPPYDRERVEELLQELPKIRTAKDIFQNLRALIR 410 +++ L +L ++ E E V + E+ + RT ++I + L+ R Sbjct: 356 SIDHCYLRIQRTILAVMQALGDIGCKESEVFGEGVNP-MTEIYRFRTMEEIGEWLKTACR 414 Query: 411 DAAAGVNDSRSTQQKRQVDQAVDYILKNYMKEGLSLQDVADQVHLSTSYFSMIFKKQTGT 470 A V +R Q + Q+++A+ Y+ +Y E LS++ V QVH+S SYFS FK TG Sbjct: 415 QAVHSVTATRHDQCRSQIEEAIAYLESHYEDENLSVKAVCKQVHMSVSYFSAAFKSHTGR 474 Query: 471 TFSEFLQDVRMKKAVELLR 489 TF E+ VRM KA ELL+ Sbjct: 475 TFIEYATAVRMDKAKELLK 493 >B3KJG1.1 B3KJG1_9BACI Response regulator receiver Length = 539 Score = 270 bits (689), Expect = 3e-70, Method: Compositional matrix adjust. Identities = 167/502 (33%), Positives = 282/502 (56%), Gaps = 23/502 (4%) Query: 1 MWKLVLIDDDHIILRGLSRNIPWEEYGFEVSASAHDGEEGLDAVERERPHVVITDIRMPF 60 M+ ++++DD+ I+ G+ I W E+G+E +G + L+AV R +P VV+TDI MP+ Sbjct: 1 MYTILIVDDEPIVREGIRNRIQWSEHGYECIGDCENGRDALEAVTRHQPDVVLTDINMPY 60 Query: 61 MDGLQLTEAIKSKFPDVKIILMTSYDEFEFAQKALKLKVFDFVLKPVENDKLLEVALRAA 120 MDGL+L+ I +FP KII++T +D+FE+AQ+A+KL+V DF+LKPV +L ++ + Sbjct: 61 MDGLELSRHITERFPKTKIIILTGFDDFEYAQQAVKLQVTDFILKPVTAAELRDMLDKLK 120 Query: 121 AEWEQERA-------LAKKVLEGVPFLRQRFYENLLRGKYRQEEIDHELAFLELPLKAER 173 E ++ER L K++ E + LR+RF E L ++ E++ L + ++PL+ Sbjct: 121 LEMDEERGHTEHLKRLKKQLNESLVLLRERFLERLASSPMKRSEMESRLDYFDIPLRGPL 180 Query: 174 YAVLLIIADDYY--ETGAGNRFGQELLKYCIHNISLEVLDSLGEGVVFELGEDEIAVICT 231 Y + D+ E A N EL + ++NI E+L VF E+++ I + Sbjct: 181 YIAMAADMDELRSDEQHADN----ELHAFALYNIMQEILAGEPGAAVFRYKENKVMTILS 236 Query: 232 GSADQQAMERKVMQMAEHIRYNAEVYLKTTVTVGTGPVCSELTGIAQSYHEAKAATDFRH 291 GS D++ + + ++AE IR + + ++K TVTVG G +C EL I S ++AA ++R Sbjct: 237 GS-DEKDLHARAQELAEDIRGSTKQFMKFTVTVGIGTICRELQDIRYSCKASEAALEYRL 295 Query: 292 IAGTNQVLSFRDTKVKQHVSGHPAVNG-GWEADLGMNIRLGFVQEALLVLEHMEKQIQSA 350 + G +QV+ D +++ SG P ++G E L IR G E + + +I SA Sbjct: 296 LIGRDQVVHITD--LEKRGSG-PLLDGIETETALVSAIRAGTGSEVKACIRRLINEIGSA 352 Query: 351 PITLERLRLLGIEIVLVIVNTFQ---SWSEPPYDRERVEELLQELPKIRTAKDIFQNLRA 407 I++E + + ++L ++ T S +E+ LL +L R+ +I + L Sbjct: 353 SISIELCYVRVLRVMLAVLQTLMEIGSNGNELIGKEK--RLLSDLYSFRSLDEIERWLNE 410 Query: 408 LIRDAAAGVNDSRSTQQKRQVDQAVDYILKNYMKEGLSLQDVADQVHLSTSYFSMIFKKQ 467 + A V +R + Q+ +AVD+I ++Y E LS++ V ++ +STSYFS +FK Sbjct: 411 VCEQALRDVAKTRKDIARSQMLEAVDFIQRHYEDEELSIKTVCSRIFMSTSYFSALFKSH 470 Query: 468 TGTTFSEFLQDVRMKKAVELLR 489 TG TF E++ +VRM+KA ELL+ Sbjct: 471 TGKTFVEYVTEVRMEKAKELLK 492 >C0Z4C7.1 C0Z4C7_BREBN Probable two-component response regulator Length = 534 Score = 270 bits (689), Expect = 4e-70, Method: Compositional matrix adjust. Identities = 167/506 (33%), Positives = 281/506 (55%), Gaps = 25/506 (4%) Query: 1 MWKLVLIDDDHIILRGLSRNIPWEEYGFEVSASAHDGEEGLDAVERERPHVVITDIRMPF 60 M+KL+L+DD+ + G+S+ I W +G+EV A A +G E L+ VER RP VV+TDI+MPF Sbjct: 1 MYKLILVDDEEDVREGVSQEIDWHSHGYEVVAKAENGREALELVERLRPDVVVTDIKMPF 60 Query: 61 MDGLQLTEAIKSKFPDVKIILMTSYDEFEFAQKALKLKVFDFVLKPVENDKLLEVALRA- 119 M+GLQL E+I +P ++II++T +DEFE+AQKA+KL++ ++VLKP +L+E + Sbjct: 61 MNGLQLAESIGRDYPAIRIIILTGFDEFEYAQKAVKLQIDEYVLKPFSASELMEALDKVK 120 Query: 120 ------AAEWEQERALAKKVLEGVPFLRQRFYENLLRGKYRQEEIDHELAFLELPLKAER 173 AA E + L + +P LR+ F +LL + Q ++ + + L++ Sbjct: 121 RRMDEEAAHRENVQLLRDSYRKSLPVLREVFLSSLLSRQLVQHDVFSKACEYGIELRSPE 180 Query: 174 YAVLLIIADDYYETGAGNRFGQELLKYCIHNISLEVLDSLGE-GVVFELGEDEIAVIC-T 231 Y V +I D + Q+L + + NI+ E L++ + G+VF L ED++ ++ T Sbjct: 181 YLVAVICVDQ------PKQEEQQLFLFAVKNIAEEQLNASKQAGIVF-LHEDQVVLLMRT 233 Query: 232 GSADQQAMERKVMQMAEHIRYNAEVYLKTTVTVGTGPVCSELTGIAQSYHEAKAATDFRH 291 + D Q +E + +AE IR E Y+ TVT+G G +++ + SY +A A D++ Sbjct: 234 KADDTQRIEVRAQHIAEEIRRTIEKYMSITVTIGIGNAVADIAALPYSYEDAMQALDYKS 293 Query: 292 IAGTNQVLSFRDTKVKQHVSGHPAVNGGWEADLGMNIRLGFVQEALLVLEHMEKQIQSAP 351 I G N+++ D V++ S ++ E +L I++G E V++ + Q+ P Sbjct: 294 ILGCNRMIVIND--VEKQASEQIRLDERREHELVRCIKMGTSTELRAVIDELFDQVAGVP 351 Query: 352 ITLERLRLLGIEIVLVIVNTFQSWSEPPYDR----ERVEELLQELPKIRTAKDIFQNLRA 407 +++E R+ +EI+ I+ T +E D+ +R LLQ + +D + + Sbjct: 352 VSIEDYRIYLLEIMTTILKTAHR-AEVDMDQLFGGQRY--LLQVMTTFTGMEDAREQITD 408 Query: 408 LIRDAAAGVNDSRSTQQKRQVDQAVDYILKNYMKEGLSLQDVADQVHLSTSYFSMIFKKQ 467 + A + R T +R + QA+DY +Y +S+ V +Q+H+S YFS IFKK+ Sbjct: 409 ICERLMASIASGRQTTYRRLITQALDYTHAHYHSPDISIHKVCEQLHISLGYFSGIFKKE 468 Query: 468 TGTTFSEFLQDVRMKKAVELLRGEEM 493 T TTF +L +RM+KA ELLR ++ Sbjct: 469 TKTTFVSYLLSLRMEKAKELLRTTDL 494 >C5EE52.1 C5EE52_9FIRM Two-component response regulator Length = 529 Score = 234 bits (598), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 156/493 (31%), Positives = 260/493 (52%), Gaps = 13/493 (2%) Query: 1 MWKLVLIDDDHIILRGLSRNIPWEEYGFEVSASAHDGEEGLDAVERERPHVVITDIRMPF 60 M+++++ DDD II RGL + I WE YG E+ A DG+E L ++ PH+++TDI+MP Sbjct: 1 MYRVLIADDDAIIRRGLKKTIDWESYGMEIVGVACDGQEALSMLKELAPHLLLTDIKMPQ 60 Query: 61 MDGLQLTEAIKSKFPDVKIILMTSYDEFEFAQKALKLKVFDFVLKPVENDKLLEVALRAA 120 M G++L + + +PD+++IL+T+Y++FE+A++A+K K D++LKP+ ++LLE L Sbjct: 61 MSGIELMKEARILYPDIQVILLTAYEDFEYAKEAIKHKACDYLLKPLAREELLESVLNTK 120 Query: 121 AEWEQERALAKKVLEGVPFLRQRFYENLLRGKYRQEEIDHELAFLELPLKAERYAVLLII 180 ++E + + +P L ++F +L+ G Y + I+ + L L + E L ++ Sbjct: 121 KQFESRMRDTHRKNKSIPLLSRQFINDLMAGYYGKARIEEAIQELGLKIYKENLIALDLL 180 Query: 181 ADDYYETGAGNRFGQELLKYCIHNISLEVLDSL-GEGV-VFELGEDEIAVICTGSADQQA 238 DYY+ + +G ELLKY ++N E+ S+ G V VF+ D + +I + Sbjct: 181 IVDYYDR-TRDLWG-ELLKYAVYNCVQELSQSVDGCAVEVFQGNADHVYIILSSQDGGCG 238 Query: 239 MERKVMQMAEHIRYNAEVYLKTTVTVGTGPVCSELTGIAQSYHEAKAATDFRHIAGTNQV 298 +E + A IR L +G G S L + S EA A +RH++ Sbjct: 239 LEEQGTGFAGKIRGTILEVLDVETALGIGNRYSGLERLEDSIQEAFTALKYRHLSEREGY 298 Query: 299 LSFRDTKVKQHVSGHPAVNGGWEADLGMNIRLGFVQEALLVLEHMEKQIQSAPITLERLR 358 F + + SG A G L + LG ++AL +LE ++ ITL LR Sbjct: 299 SVFHEAVTWE--SGKRAELGEGNKLLIQKVLLGSREQALGLLEQCRARVLKEGITLGNLR 356 Query: 359 LLGIEIVLVIVNTFQSWSEPPYDRERVEELLQELPKIRTAKD---IFQNLRALIRDAAAG 415 + I ++ ++ +WS E + + +I + D IF + LIRD AG Sbjct: 357 MWCIGLIAHLLQETGNWSRL----EGSHDYYEYCDRICASSDLSRIFGIVADLIRDICAG 412 Query: 416 VNDSRSTQQKRQVDQAVDYILKNYMKEGLSLQDVADQVHLSTSYFSMIFKKQTGTTFSEF 475 VN++++ + +A YI NY LSL DVA+++H+S Y S++FKK TFS+F Sbjct: 413 VNETQADSKTVLAHKAETYIRNNYPDSELSLNDVAEELHVSPVYLSILFKKIKQVTFSDF 472 Query: 476 LQDVRMKKAVELL 488 L ++RM+ A EL+ Sbjct: 473 LSEIRMEAARELV 485 >B1D7Q5.1 B1D7Q5_9BACL Two component transcriptional regulator, AraC family Length = 530 Score = 215 bits (548), Expect = 9e-54, Method: Compositional matrix adjust. Identities = 155/508 (30%), Positives = 266/508 (52%), Gaps = 32/508 (6%) Query: 4 LVLIDDDHIILRGLSRNIPWEEYGFEVSASAHDGEEGLDAVERERPHVVITDIRMPFMDG 63 + ++DD ++ G+S IPW YG E+ +A DG+EGL P +++TDIRMP MDG Sbjct: 1 MCVLDDIISVIDGISLGIPWANYGIEIIGTALDGDEGLKMALELNPDILLTDIRMPVMDG 60 Query: 64 LQLTEAIKSKFPDVKIILMTSYDEFEFAQKALKLKVFDFVLKPVENDKLLEVALRAAAEW 123 L+LT I K P K+IL++ Y EF +AQ+A++ FDFV KP + ++EV L+A E Sbjct: 61 LELTRRIIEKSPACKVILLSGYTEFSYAQQAIRYGAFDFVAKPFSMEDIIEVVLKATEEI 120 Query: 124 EQERALAKKVL-------EGVPFLRQRFYENLLRGKYRQEEIDHELAFLELPLKAERYAV 176 E ER+ K++ E P LRQ ++ L+R +E + FLE+ LK E + V Sbjct: 121 ELERSKHKRIYEMEARVRESKPLLRQEYFNLLIRYSSSEESARAKWDFLEIDLKREGFVV 180 Query: 177 LLIIADDYYETGAGNRFGQ-ELLKYCIHNISLEVLDSLGEGVVFELGEDEIAVICTGSAD 235 ++ D + +T G+ EL +Y + NI E ++ +GVVF + + +I S D Sbjct: 181 MVAEIDRFSKTIQTLPIGEVELTRYALQNILEETINEYTQGVVFRESMNRLVII-YNSTD 239 Query: 236 QQAMERKVMQMAEHIRYNAEVYLKTTVTVGTGPVCSELTGIAQSYHEAKAATDFRHIAGT 295 Q +E +AE N +Y + TV++G + ++ I Y +A +A + G Sbjct: 240 Q--IESGA--LAEICCNNCALYSRHTVSIGVSLSTNLISEIHLGYQQAISALSYNFYTGG 295 Query: 296 NQVLSFRD-TKVKQHVSGHPAVNGGWEADLGMNIRLGFVQEALLVLEHMEK---QIQSAP 351 N + D ++ QH+ + E +L +R G + AL VL+ + + +IQ P Sbjct: 296 NGAFRYGDFGQMSQHLRTYSL---DQEKELLFAVRSGNQEAALGVLQQIYEDCAKIQPLP 352 Query: 352 ITLERLRLLGIEIVLVIVNTFQSWSEPPYDRERVEELLQELPKIRTAK-----DIFQNLR 406 + L + E+V +++ E +E ++EL E+ + ++ ++L Sbjct: 353 -NPQYLITMYDELVYMVLRVL----EEKLHKEDLQELKAEIEAHKKTDRMSLLELQKSLE 407 Query: 407 ALIRDAAAGVNDSRSTQQKRQVDQAVDYILKNYMKEGLSLQDVADQVHLSTSYFSMIFKK 466 L + + R+T+ +R + +A++Y +K + LS+ + A VHLS+SYFS +FKK Sbjct: 408 QLCMNGCVLQDKHRTTEAERIIHRAIEY-MKGNLHLDLSVNECATLVHLSSSYFSNLFKK 466 Query: 467 QTGTTFSEFLQDVRMKKA-VELLRGEEM 493 TG TF +F+ + R+ +A + L++G ++ Sbjct: 467 VTGQTFLQFVTNERIDQAKLMLMKGHQV 494 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,968,030,626 Number of extensions: 118827050 Number of successful extensions: 403235 Number of sequences better than 1.0e-05: 9510 Number of HSP's gapped: 413093 Number of HSP's successfully gapped: 9646 Length of query: 535 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 394 Effective length of database: 1,732,333,088 Effective search space: 682539236672 Effective search space used: 682539236672 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)