BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0334.0006.p (596 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C5EE53.1 C5EE53_9FIRM Histidine kinase internal region 272 6e-71 B3KJG0.1 B3KJG0_9BACI Histidine kinase internal region 216 7e-54 C0D1A2.1 C0D1A2_9CLOT Putative uncharacterized protein 215 9e-54 A7B0I5.1 A7B0I5_RUMGN Putative uncharacterized protein 214 2e-53 B1D4P2.1 B1D4P2_9BACL Multi-sensor signal transduction histidine... 211 1e-52 >C5EE53.1 C5EE53_9FIRM Histidine kinase internal region Length = 599 Score = 272 bits (696), Expect = 6e-71, Method: Compositional matrix adjust. Identities = 175/582 (30%), Positives = 299/582 (51%), Gaps = 29/582 (4%) Query: 25 VPITGTVSYILASQQLKINAETSLNDTLSQTRDFMNDRLTAVLAEMAVLDGSTELRSLFY 84 + I GT ++ Q+ ++ ++ ++L+Q+ ++ R+ ++ ++ S+++ SL Sbjct: 33 ILIMGTTFQRMSYNQVTESSRANMLNSLTQSTSVLDSRMADLMERFQYIENSSDMLSLAL 92 Query: 85 RANRSDFSMTP-QDYLTVGRNIDKVYANLYSIIDSILVYYRNGAISMYRRDSL--HTDFS 141 ++ + Q Y+ + ++ID + + S +DS+++ + + MYR + + DF+ Sbjct: 93 VMSQENVDRAKGQYYINLRKSIDDQFVSSGSFLDSVIIDFNDSRFRMYRCEDIPVKIDFN 152 Query: 142 YDMSPYPGYSGGNTAQMRWLIPASNRL------ENDGGNTA--SLYKWIAGGDGKPD-GX 192 YD + G N + W + + EN+ N SLY+ + G G+P G Sbjct: 153 YD-----AWYGRNQSIYNWSFLHDDTIFQVTDAENNRKNNRVFSLYR-LYGKPGQPGRGG 206 Query: 193 XXXXXXXXXXXXXXSTPKISASGYMLLASPDGTVSAKAASAGDARVDDEALRSMLMAQTE 252 + P IS +GY+ L DG++ + +++LR L + Sbjct: 207 IVFNIRESMFRDMLTIPDISENGYVALIH-DGSLIRYKDVDESYTLSEQSLRQ-LQQMAD 264 Query: 253 ASGKLEMTSRTGMRIVVLYETIAINNWRLAVVYPQAEIYEKVNYIKYXXXXXXXXXXXXX 312 S +++ S +G ++V + N W +A + P E++ V ++ Sbjct: 265 VSAGIKVKSVSGQEMMVYTRHLKTNGWLVAALLPTNEMFHDVRTMQNSIHFTMIAVIVCS 324 Query: 313 XXXXXXXXXXXXRPVTRLTRQVNSIEEGHLDVQIIESDNYEIGILSKGIKDMMERIKHLL 372 P+ RLT V S+E+ + EI ILS I +++ R++ L+ Sbjct: 325 VLACVVLSRLIVLPIKRLTDTV-SVEDVTSIANVSSGGAREIQILSDKINELLSRVRQLI 383 Query: 373 SQVEYEQEQKRISEFAALQAQIHPHFLYNTLYSIKQLCELGETAEASRMISALSHYFRIS 432 QV+ EQE+KR +E + +Q QI+PHFLYNTLYS++QLCEL E+ EAS M+ ALS++FR Sbjct: 384 EQVKEEQEKKREAELSLMQEQINPHFLYNTLYSVQQLCELDESKEASAMVLALSNFFRTG 443 Query: 433 ISRGDELIPVETELEHIRQYLTIQQMRYGDSIRYEMDVAPEMLSVPIVKLTLQPLVENAI 492 +SRG+++I ++TE+ H++ YL IQ M+YGD YE+++AP++ I+KLTLQPLVENA+ Sbjct: 444 LSRGEDVITIDTEINHVKNYLVIQHMKYGDKFEYEIEIAPDIRDCRILKLTLQPLVENAL 503 Query: 493 YHGIKKVRRPGFIHISGRMEGELCRIRIEDNGFGMDQELPXXXXXXXLAAGEEPQEE--P 550 +HGI+ G I I+G+ EG + D G GM E QEE Sbjct: 504 HHGIQNQAGKGMITITGKREGGRILFEVRDTGAGMASERLEQVRKSM------NQEEGYS 557 Query: 551 PVGFGVRNVHRRLQLHYGSSFGLAYDSTEGQGTTVTVTFPLS 592 V FG+RNV+ RL L+Y GL +S +G+GT + V P++ Sbjct: 558 QVSFGLRNVYSRLMLYYDGEAGLEIESVQGRGTVIKVYIPVT 599 >B3KJG0.1 B3KJG0_9BACI Histidine kinase internal region Length = 598 Score = 216 bits (549), Expect = 7e-54, Method: Compositional matrix adjust. Identities = 115/266 (43%), Positives = 163/266 (61%), Gaps = 6/266 (2%) Query: 325 RPVTRLTRQVNSIEEGHLDVQIIESDNYEIGILSKGIKDMMERIKHLLSQVEYEQEQKRI 384 RP+ +L ++ +E+G+ D+++ + EI L++ M+ +IK L+ Q+ EQE KR Sbjct: 324 RPIKKLQEKMMEVEKGNFDIRVPVGHSREISGLARSFNVMVLKIKELMYQIVVEQEIKRK 383 Query: 385 SEFAALQAQIHPHFLYNTLYSIKQLCELGETAEASRMISALSHYFRISISRGDELIPVET 444 SE ALQAQI+PHFLYNTL SI + E + E M SAL+ FR S+S+G ELIP+ T Sbjct: 384 SELNALQAQINPHFLYNTLDSIIWMAESKKHDEVILMTSALARLFRASLSKGKELIPIAT 443 Query: 445 ELEHIRQYLTIQQMRYGDSIRYEMDVAPEMLSVPIVKLTLQPLVENAIYHGIKKVRRPGF 504 E+EHI YL IQQMRY D I + +D+ + +K+ LQPLVENAIYHGIK PG Sbjct: 444 EVEHITNYLKIQQMRYQDKITFALDIDRGLYPYLTLKVLLQPLVENAIYHGIKNKEGPGT 503 Query: 505 IHISGRMEGELCRIRIEDNGFGMDQELPXXXXXXXLAAGEEPQEEPPVGFGVRNVHRRLQ 564 I I+G +++D+G GMDQ L + E + V G+ NVH+R+Q Sbjct: 504 ITITGVRRDTRIEFQVKDDGIGMDQS----KVETLLTSKEGTRSRNSV--GIANVHQRIQ 557 Query: 565 LHYGSSFGLAYDSTEGQGTTVTVTFP 590 L++G+ +GL+Y S G GT+VT+ P Sbjct: 558 LYFGTEYGLSYASVPGSGTSVTLVIP 583 >C0D1A2.1 C0D1A2_9CLOT Putative uncharacterized protein Length = 595 Score = 215 bits (548), Expect = 9e-54, Method: Compositional matrix adjust. Identities = 113/265 (42%), Positives = 157/265 (59%), Gaps = 4/265 (1%) Query: 326 PVTRLTRQVNSIEEGHLDVQIIESDNYEIGILSKGIKDMMERIKHLLSQVEYEQEQKRIS 385 P+ L + VN IEEGHL+ + +YEI L I++M +I+ L++ + E E KR S Sbjct: 323 PIKELEKSVNEIEEGHLETNVYAGGSYEIQHLGNSIQNMARQIRRLMNDIVAEHESKRKS 382 Query: 386 EFAALQAQIHPHFLYNTLYSIKQLCELGETAEASRMISALSHYFRISISRGDELIPVETE 445 EF LQ+QI+PHFLYNTL I + E +EA + ++AL+ +FRIS+S+G +IPV E Sbjct: 383 EFDTLQSQINPHFLYNTLDIIVWMIENERQSEAVKAVTALARFFRISLSKGKSIIPVRDE 442 Query: 446 LEHIRQYLTIQQMRYGDSIRYEMDVAPEMLSVPIVKLTLQPLVENAIYHGIKKVRRPGFI 505 LEH+R YL IQ MRY + Y ++ + + +KL LQPLVENAIYHG++ + G I Sbjct: 443 LEHVRNYLMIQSMRYKNKFTYSIEAGEGVEELASLKLMLQPLVENAIYHGMEFMDGDGEI 502 Query: 506 HISGRMEGELCRIRIEDNGFGMDQELPXXXXXXXLAAGEEPQEEPPVGFGVRNVHRRLQL 565 I EG+ + + DNG GM QE AA E G GVRNV+ R++L Sbjct: 503 LIKAWREGDDLYMSVGDNGLGMTQE----QVENLFAAAEHVPSRRGSGIGVRNVNERIKL 558 Query: 566 HYGSSFGLAYDSTEGQGTTVTVTFP 590 ++G +GL DS +GTTVT P Sbjct: 559 YFGKEYGLVIDSEPDEGTTVTAHLP 583 >A7B0I5.1 A7B0I5_RUMGN Putative uncharacterized protein Length = 602 Score = 214 bits (546), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 120/273 (43%), Positives = 164/273 (60%), Gaps = 9/273 (3%) Query: 325 RPVTRLTRQVNSIEEGHLDVQIIE-SDNYEIGILSKGIKDMMERIKHLLSQVEYEQEQKR 383 +P+ RL ++ +E+G + +E + EIG LSK M ++I L+ Q YEQ+QKR Sbjct: 330 KPLRRLRDSMSLVEKGDFEQASVEITAENEIGSLSKSFNAMTQKIHALMEQNIYEQKQKR 389 Query: 384 ISEFAALQAQIHPHFLYNTLYSIKQLCELGETAEASRMISALSHYFRISISRGDELIPVE 443 SE ALQAQI+PHFLYNTL SI + E GE + M SAL+ R SIS E I V Sbjct: 390 KSEMKALQAQINPHFLYNTLDSIIWMSEAGENDQVVLMTSALAKLLRQSISNDREQITVA 449 Query: 444 TELEHIRQYLTIQQMRYGDSIRYEMDVAPEMLSVPIVKLTLQPLVENAIYHGIKKVRRPG 503 E++++R YLTIQ+MRY D + Y +DV +L V I+K LQPLVENAIYHG+K G Sbjct: 450 EEIDYVRSYLTIQKMRYKDKLEYTIDVEERILDVRIIKFVLQPLVENAIYHGLKYKETKG 509 Query: 504 FIHISGRMEGELCRIRIEDNGFGMDQ-ELPXXXXXXXLAAGEEPQEEPPVGFGVRNVHRR 562 + I G G + + D+G GM++ EL ++ ++ G GV NV +R Sbjct: 510 NLDIRGYRRGNRVCLVVADDGAGMEESELEHILE-------KKEKKTKSNGVGVYNVQKR 562 Query: 563 LQLHYGSSFGLAYDSTEGQGTTVTVTFPLSGGK 595 LQL+YG +G++Y S +G+GT TVT PL GGK Sbjct: 563 LQLYYGPEYGISYISRKGEGTVATVTIPLDGGK 595 >B1D4P2.1 B1D4P2_9BACL Multi-sensor signal transduction histidine kinase Length = 596 Score = 211 bits (538), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 116/274 (42%), Positives = 164/274 (59%), Gaps = 10/274 (3%) Query: 325 RPVTRLTRQVNSIEEGHLDVQIIESDNYEIGILSKGIKDMMERIKHLLSQVEYEQEQKRI 384 RP+ +L + +E+G ++++ + EI L++ M+ +I+ L+SQV EQE KR Sbjct: 324 RPIKQLQEHMKKVEKGIFNIRVPIGNPREIASLARTFNLMVVKIEELMSQVVREQEIKRK 383 Query: 385 SEFAALQAQIHPHFLYNTLYSIKQLCELGETAEASRMISALSHYFRISISRGDELIPVET 444 SE ALQAQI+PHFLYNTL SI + E +T E M SAL+ FR SISRG EL+ + T Sbjct: 384 SELTALQAQINPHFLYNTLDSIIWMAEGKKTDEVVLMTSALARLFRSSISRGQELVSIRT 443 Query: 445 ELEHIRQYLTIQQMRYGDSIRYEMDVAPEMLSVPIVKLTLQPLVENAIYHGIKKVRRPGF 504 E+EH+ YLTIQ++RY D + + +DV P++ + +K+ LQPL+ENAIYHGIK G Sbjct: 444 EIEHVANYLTIQKIRYKDKLDFHIDVDPDIYAYRTLKVLLQPLLENAIYHGIKNRIGTGT 503 Query: 505 IHISGRMEGELCRIRIEDNGFGMDQELPXXXXXXXLAAGEEPQ--EEPPVGFGVRNVHRR 562 I ++G + + DNG GM+ E L EP+ + G GV NVH R Sbjct: 504 IQVTGGKRDGYIWLEVSDNGVGMEAE--------ALRTILEPRRSDRESKGVGVVNVHER 555 Query: 563 LQLHYGSSFGLAYDSTEGQGTTVTVTFPLSGGKE 596 +QL++G +GL Y S + +GTTVTV G E Sbjct: 556 IQLYFGKDYGLTYKSVQDEGTTVTVRIAAIEGDE 589 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.135 0.386 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,200,020,578 Number of extensions: 124345711 Number of successful extensions: 329541 Number of sequences better than 1.0e-05: 2044 Number of HSP's gapped: 326542 Number of HSP's successfully gapped: 2044 Length of query: 596 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 454 Effective length of database: 1,722,912,073 Effective search space: 782202081142 Effective search space used: 782202081142 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 134 (56.2 bits)