BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0311.0025.p (380 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A6DP20.1 A6DP20_9BACT 3-dehydroquinate synthase 466 e-129 C4Z915.1 C4Z915_9FIRM 3-dehydroquinate synthase 438 e-121 A7VC26.1 A7VC26_9CLOT Putative uncharacterized protein 421 e-116 B0MQA2.1 B0MQA2_9FIRM Putative uncharacterized protein 420 e-115 A4J3A3.1 A4J3A3_DESRM 3-dehydroquinate synthase EC=4.2.3.4 291 1e-76 >A6DP20.1 A6DP20_9BACT 3-dehydroquinate synthase Length = 382 Score = 466 bits (1199), Expect = e-129, Method: Compositional matrix adjust. Identities = 227/373 (60%), Positives = 283/373 (75%), Gaps = 1/373 (0%) Query: 4 TFQVMLKKVVDDSYAIEIGEQLFDSLIADLQQGLVPNVSKYAIITDSTVEPLYGRPLLER 63 TF V LKK VDDSY I+IG LF +LI DL+ GL P +K A+ITDS V PLY L+ Sbjct: 3 TFHVPLKKTVDDSYDIQIGFNLFSTLIEDLKNGLFPKANKLALITDSNVLPLYASNLILA 62 Query: 64 LRQNGFAAELFSFPAGEASKTRETKALLEDQLLSRAYGRDSCIIAVGGGAVTDLAGFLAG 123 +++ GF ELFS PAGE SKTRETK LE+++L + +GRDS +IA+GGG V+DLAGFLAG Sbjct: 63 IKEEGFTVELFSMPAGEHSKTRETKIRLENEMLDKGFGRDSAVIALGGGVVSDLAGFLAG 122 Query: 124 TFGRGVPSLNYATTLLAAADASVGGKTGVNTPVATNLIGLFHQPRKVYIDLAAWRTLPAR 183 TFGRG+P NY+TTLL+AADASVGGKT V+TP ATNLIGLF+QP KVYID+A W TLP R Sbjct: 123 TFGRGIPFANYSTTLLSAADASVGGKTAVDTPHATNLIGLFNQPVKVYIDIATWSTLPDR 182 Query: 184 EFRSGLAETIRHACLGDADFFSYLEENMGKVISDRGQLVLDAGVCEHIALANCRIKYEVV 243 E R+GLAETI+HACL DA+FF++LE N+ K+ S LDA CE IA ANCRIKY+VV Sbjct: 183 EVRAGLAETIKHACLADAEFFAWLEANITKIASAE-DAKLDAEACEFIAEANCRIKYDVV 241 Query: 244 EQDERESNLRQILNLGHTAGRALEALSGYTLLHGEAVAIGLVVQAKLGVKRGYMTEDQAE 303 +DE+E+NLRQ+LNLGHTAGRA+E L Y LLHGE VA+GL +QA L K ++++ Sbjct: 242 SRDEKEANLRQVLNLGHTAGRAMETLFEYQLLHGECVAVGLSIQALLANKLELISDEDHR 301 Query: 304 RLIALLKKAGLPTEMPASIPNRQLVDKMYTDKKVRSGRIRFVFQDGIGAMKRFADGSYSI 363 R+ AL+ GLPTE+P I +LV+KMYTDKKVRSG+IRFV DGIGAMK F +GSY+ Sbjct: 302 RVDALIALCGLPTEVPEEISTEELVEKMYTDKKVRSGQIRFVLMDGIGAMKTFENGSYTK 361 Query: 364 PVEEADILAALEE 376 + + +++ + E Sbjct: 362 ALADDFLISTINE 374 >C4Z915.1 C4Z915_9FIRM 3-dehydroquinate synthase Length = 370 Score = 438 bits (1127), Expect = e-121, Method: Compositional matrix adjust. Identities = 214/364 (58%), Positives = 276/364 (75%), Gaps = 6/364 (1%) Query: 5 FQVMLKKVVDDSYAIEIGEQLFDSLIADLQQGLVPNVSKYAIITDSTVEPLYGRPLLERL 64 F V LKKVVDD+Y IEIG L D+L++DL+ GL + K+A+ITD+ V Y P+ E++ Sbjct: 4 FNVELKKVVDDTYDIEIGYNLSDTLVSDLENGLAGKIKKFAVITDTNVRDPYALPICEKI 63 Query: 65 RQNGFAAELFSFPAGEASKTRETKALLEDQLLSRAYGRDSCIIAVGGGAVTDLAGFLAGT 124 + G++ +LF FPAGE SK+RETKA +ED +L + Y RD CIIAVGGG VTDL+GF+AGT Sbjct: 64 KHAGYSVDLFVFPAGEKSKSRETKAKIEDAMLKKGYRRDCCIIAVGGGVVTDLSGFIAGT 123 Query: 125 FGRGVPSLNYATTLLAAADASVGGKTGVNTPVATNLIGLFHQPRKVYIDLAAWRTLPARE 184 +GRGVP +NYATTLLAAADASVGGKT ++TP+ATN IGLF+QP+KVYID+AAW+TLP R+ Sbjct: 124 YGRGVPFINYATTLLAAADASVGGKTAIDTPLATNTIGLFNQPQKVYIDIAAWKTLPQRQ 183 Query: 185 FRSGLAETIRHACLGDADFFSYLEENMGKVISDRGQLVLDAGVCEHIALANCRIKYEVVE 244 SG+AETI+HACLG D F ++EEN+ + S CE+IA NCRIKY VV Sbjct: 184 MASGMAETIKHACLGSEDMFEFIEENLDDIYS------FKKFACEYIAENNCRIKYNVVM 237 Query: 245 QDERESNLRQILNLGHTAGRALEALSGYTLLHGEAVAIGLVVQAKLGVKRGYMTEDQAER 304 +DERE+ LR+ LNLGHT GRA+E +S Y LLHGEA++IG+ QA + + GYM+E+QAER Sbjct: 238 KDEREAGLRETLNLGHTVGRAIETVSDYKLLHGEALSIGMAAQALMSARLGYMSEEQAER 297 Query: 305 LIALLKKAGLPTEMPASIPNRQLVDKMYTDKKVRSGRIRFVFQDGIGAMKRFADGSYSIP 364 +I L ++AGLPT +P I +LV K+YTDKKVR G++RFV Q GIGA FA G Y+ P Sbjct: 298 VIKLYERAGLPTRIPDYIDREELVKKLYTDKKVRDGKLRFVLQKGIGATVEFAPGVYAKP 357 Query: 365 VEEA 368 +EE+ Sbjct: 358 IEES 361 >A7VC26.1 A7VC26_9CLOT Putative uncharacterized protein Length = 372 Score = 421 bits (1082), Expect = e-116, Method: Compositional matrix adjust. Identities = 212/365 (58%), Positives = 270/365 (73%), Gaps = 6/365 (1%) Query: 4 TFQVMLKKVVDDSYAIEIGEQLFDSLIADLQQGLVPNVSKYAIITDSTVEPLYGRPLLER 63 F+V LKKVVDDSY IEIG +L LI DL+ GLV +SK+ ++TDS V+ LY + + Sbjct: 5 NFKVELKKVVDDSYEIEIGYELEQKLIDDLKAGLVGKISKFVVVTDSNVKELYADKIYKM 64 Query: 64 LRQNGFAAELFSFPAGEASKTRETKALLEDQLLSRAYGRDSCIIAVGGGAVTDLAGFLAG 123 L + G+ +L SFPAGE SKTR TK +ED +L++ Y RD CIIAVGGG VTDLAGF+AG Sbjct: 65 LEEAGYKTDLISFPAGELSKTRATKEYVEDTMLAKGYRRDCCIIAVGGGVVTDLAGFVAG 124 Query: 124 TFGRGVPSLNYATTLLAAADASVGGKTGVNTPVATNLIGLFHQPRKVYIDLAAWRTLPAR 183 T+GRG+P +NYATTLLAAADASVGGKT V+TP+ATNLIGLF+QP+KVY+D+A W+TLP R Sbjct: 125 TYGRGIPFINYATTLLAAADASVGGKTAVDTPLATNLIGLFNQPQKVYLDIATWKTLPQR 184 Query: 184 EFRSGLAETIRHACLGDADFFSYLEENMGKVISDRGQLVLDAGVCEHIALANCRIKYEVV 243 + SGLAETI+HACL D +FF YL E++ V++ + + VC HIA NC IKY+VV Sbjct: 185 QLSSGLAETIKHACLADREFFDYLSEHIEDVLAVKDE------VCRHIAEKNCEIKYQVV 238 Query: 244 EQDERESNLRQILNLGHTAGRALEALSGYTLLHGEAVAIGLVVQAKLGVKRGYMTEDQAE 303 +DERES LR++LNLGHT GRA+E +S Y LLHGEAVAIGLV + K+ GY T + Sbjct: 239 MKDERESGLREVLNLGHTVGRAIETVSDYKLLHGEAVAIGLVAEVKMAEHFGYCTAEDEA 298 Query: 304 RLIALLKKAGLPTEMPASIPNRQLVDKMYTDKKVRSGRIRFVFQDGIGAMKRFADGSYSI 363 ++A+LK+A LPTE+P I LV K+YTDKKVR G +RFV Q GIGA++ F Y+ Sbjct: 299 AMVAMLKQADLPTEIPDYIDREALVKKLYTDKKVRDGHLRFVLQHGIGAIEVFDGDQYAK 358 Query: 364 PVEEA 368 + E+ Sbjct: 359 AIPES 363 >B0MQA2.1 B0MQA2_9FIRM Putative uncharacterized protein Length = 369 Score = 420 bits (1079), Expect = e-115, Method: Compositional matrix adjust. Identities = 210/373 (56%), Positives = 271/373 (72%), Gaps = 6/373 (1%) Query: 5 FQVMLKKVVDDSYAIEIGEQLFDSLIADLQQGLVPNVSKYAIITDSTVEPLYGRPLLERL 64 F LKK+VDDSY IEIG L D+LI+D++ GL + K+A++TDS VE LY + + E+L Sbjct: 3 FFCELKKIVDDSYDIEIGRGLSDTLISDIKNGLCGRIKKFAVVTDSIVESLYAKGIYEKL 62 Query: 65 RQNGFAAELFSFPAGEASKTRETKALLEDQLLSRAYGRDSCIIAVGGGAVTDLAGFLAGT 124 G++A++F P GE SKTR K +ED +L + Y RD C+IAVGGG V+DLAGF+AGT Sbjct: 63 ISAGYSADMFVIPEGEKSKTRAMKEFVEDSMLEKGYRRDCCVIAVGGGVVSDLAGFVAGT 122 Query: 125 FGRGVPSLNYATTLLAAADASVGGKTGVNTPVATNLIGLFHQPRKVYIDLAAWRTLPARE 184 FGRGVP +NYATTLLAAADASVGGKT V+TP+ATNLIGLF+QP KVY+D+ W+TLP R+ Sbjct: 123 FGRGVPFINYATTLLAAADASVGGKTAVDTPLATNLIGLFNQPEKVYLDIETWKTLPERQ 182 Query: 185 FRSGLAETIRHACLGDADFFSYLEENMGKVISDRGQLVLDAGVCEHIALANCRIKYEVVE 244 SGLAETI+HACL D + F YLE+N+ K+ LV D CE+IA NC +KY+VV Sbjct: 183 LSSGLAETIKHACLADGEMFDYLEKNIEKI------LVNDKDACEYIAEHNCAVKYKVVM 236 Query: 245 QDERESNLRQILNLGHTAGRALEALSGYTLLHGEAVAIGLVVQAKLGVKRGYMTEDQAER 304 +DERES LR++LNLGHT GRA+E +S Y LLHGEAV+IGL+ QAKLG K GY++ + R Sbjct: 237 KDERESGLREVLNLGHTVGRAIETVSDYKLLHGEAVSIGLIAQAKLGEKYGYISPENVSR 296 Query: 305 LIALLKKAGLPTEMPASIPNRQLVDKMYTDKKVRSGRIRFVFQDGIGAMKRFADGSYSIP 364 +I L ++A LP +P I LV K+YTDKKVR G++R VFQ IG + F D Y+ Sbjct: 297 VIKLCERAKLPIAIPDYIDKTALVRKLYTDKKVRDGKLRMVFQKEIGDVMCFGDNDYAKQ 356 Query: 365 VEEADILAALEEM 377 + E +I ++EM Sbjct: 357 ITEPEIAEVIDEM 369 >A4J3A3.1 A4J3A3_DESRM 3-dehydroquinate synthase EC=4.2.3.4 Length = 359 Score = 291 bits (744), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 157/362 (43%), Positives = 215/362 (59%), Gaps = 15/362 (4%) Query: 16 SYAIEIGEQLFDSLIADLQQGLVPNVSKYAIITDSTVEPLYGRPLLERLRQNGFAAELFS 75 SY I I + D + L + P K ++TD V PLY ++E L+ GF + Sbjct: 12 SYPIYIASAILDKIGTYLSEQ--PLGKKVLLVTDQQVAPLYAPRVIESLKNAGFKVAVAE 69 Query: 76 FPAGEASKTRETKALLEDQLLSRAYGRDSCIIAVGGGAVTDLAGFLAGTFGRGVPSLNYA 135 PAGE SKT E + L D A R S +IA+GGG V DLAGF+A T+ RGVP + Sbjct: 70 IPAGEPSKTLEQASRLYDLAFDHALDRQSSVIALGGGVVGDLAGFVAATYMRGVPFIQIP 129 Query: 136 TTLLAAADASVGGKTGVNTPVATNLIGLFHQPRKVYIDLAAWRTLPAREFRSGLAETIRH 195 TTLLA D+SVGGK VN N+IG F+QP+ V ID+A +TLP RE ++GLAE I++ Sbjct: 130 TTLLAQVDSSVGGKVAVNHSRGKNMIGAFYQPQMVMIDVATLQTLPERELKAGLAEVIKY 189 Query: 196 ACLGDADFFSYLEENMGKVISDRGQLVLDAGVCEHIALANCRIKYEVVEQDERESNLRQI 255 + D FF++LE+N ++++ LD E +A C+IK VVEQDERE R I Sbjct: 190 GVIWDGSFFTWLEKNYSRILN------LDTTALEQVAETCCKIKASVVEQDEREQGCRAI 243 Query: 256 LNLGHTAGRALEALSGY-TLLHGEAVAIGLVVQAKLGVKRGYMTEDQAERLIALLKKAGL 314 LN GHT G A+E+LSGY T LHGEAVA+G++ A+L + G +++ ER+ L+ GL Sbjct: 244 LNYGHTVGHAIESLSGYGTYLHGEAVAMGMISAARLALNEGILSQQDFERIYRLISAVGL 303 Query: 315 PTEMPASIPNRQLVDKMYTDKKVRSGRIRFVFQDGIGAMKRFADGSYSIPVEEADILAAL 374 PTE+P + + ++D MY DKK G++ FV +G + F D V+EADILA L Sbjct: 304 PTELPRGLGPQDIIDSMYHDKKTVLGKLVFVLPRSLGQVDIFKD------VKEADILAVL 357 Query: 375 EE 376 + Sbjct: 358 SQ 359 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.137 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,179,220,711 Number of extensions: 92382807 Number of successful extensions: 255190 Number of sequences better than 1.0e-05: 1660 Number of HSP's gapped: 251425 Number of HSP's successfully gapped: 1666 Length of query: 380 Length of database: 3,060,696,203 Length adjustment: 137 Effective length of query: 243 Effective length of database: 1,770,017,148 Effective search space: 430114166964 Effective search space used: 430114166964 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 132 (55.5 bits)