BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0311.0013.p (407 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A8U754.1 A8U754_9LACT Acetyl-CoA acetyltransferase 558 e-157 Q183B0.1 Q183B0_CLOD6 Putative acetyl-CoA acetyltransferase EC=2... 553 e-155 A8MFL5.1 A8MFL5_ALKOO Acetyl-CoA acetyltransferase EC=2.3.1.9 526 e-147 Q898X5.1 Q898X5_CLOTE Acetyl-coA acetyltransferase EC=2.3.1.9 519 e-145 C4IED4.1 C4IED4_CLOBU Acetyl-CoA acetyltransferase (Acetoacetyl-... 518 e-145 >A8U754.1 A8U754_9LACT Acetyl-CoA acetyltransferase Length = 392 Score = 558 bits (1439), Expect = e-157, Method: Compositional matrix adjust. Identities = 267/392 (68%), Positives = 318/392 (81%) Query: 14 MKEVVIVSAVRTAVGSFGGVFKNVPAVTLGTVAVKGALAKINLDPAEVDEVILGNVLQAG 73 M E VIVSA+RT VGSFGG FK+V AV LG VK A+ I LDPA +DE+I GNVL AG Sbjct: 1 MTEAVIVSALRTPVGSFGGAFKDVSAVDLGAAVVKKAIDSIGLDPATIDEMIFGNVLSAG 60 Query: 74 LGQNVARQISIQAGIPMEVPSYTINKVCGSGLKSVQLAAQTILXXXXXXXXXXXXXNMSQ 133 LGQNVARQ++I+AGIP VPS+ INKVCGSGLK+V LAAQ+IL +MSQ Sbjct: 61 LGQNVARQVAIKAGIPKHVPSFAINKVCGSGLKTVALAAQSILSGDNEIVIAGGTESMSQ 120 Query: 134 APYLLPTTRWGQRMGDGIVIDSMVHDGLTDAFNQYHMGITAENIAEKYNITREMQDKLAA 193 APY+LP RWG+RMG+G +ID+M+ DGLTDAF HMGITAENI EKY TRE QD+LA Sbjct: 121 APYVLPDARWGKRMGNGQMIDTMLKDGLTDAFTDIHMGITAENIVEKYQFTREQQDELAV 180 Query: 194 ASQNKAEKAIKEGKFKEEIIPVEIPQRKGAPVVANTDEYPRMGVTAESLAELKPAFKKDG 253 SQN AEKA+ G+FKEEI+P+E+PQR+G P V +TDE+PR G T E++A+LKPAFKKDG Sbjct: 181 RSQNNAEKAVTSGRFKEEIVPIEVPQRRGGPKVIDTDEHPRFGTTNEAMAKLKPAFKKDG 240 Query: 254 TVTAANASGLNDGAAILIVMSKSKAERLGLKPLVTIKAVECAGVAPEIMGTGPIPATKKA 313 +VTA NASGLNDGAA+LIVMS+ KA+ LGLKPL TIK+ AGV P+IMG GPIPAT+KA Sbjct: 241 SVTAGNASGLNDGAAVLIVMSREKADELGLKPLATIKSYASAGVDPKIMGCGPIPATQKA 300 Query: 314 LATAGITVQDLDLVEANEAFASQALCVVNELGINMDMVNVNGGAIALGHPIGASGARILV 373 L AG+TV+DLDL+EANEAFA+QAL V+ +L N D+VNVNGGAIALGHP+GASGARILV Sbjct: 301 LKKAGLTVEDLDLIEANEAFAAQALSVITDLKFNTDIVNVNGGAIALGHPVGASGARILV 360 Query: 374 TLIHEMERRKVQTGLATLCIGGGQGIAMIVER 405 TL+HEME+R + GLATLCIGGGQG+++IVER Sbjct: 361 TLLHEMEKRDSKRGLATLCIGGGQGMSLIVER 392 >Q183B0.1 Q183B0_CLOD6 Putative acetyl-CoA acetyltransferase EC=2.3.1.9 Length = 392 Score = 553 bits (1424), Expect = e-155, Method: Compositional matrix adjust. Identities = 265/392 (67%), Positives = 324/392 (82%) Query: 14 MKEVVIVSAVRTAVGSFGGVFKNVPAVTLGTVAVKGALAKINLDPAEVDEVILGNVLQAG 73 MK+VVIVSAVRT +GSFGGVFKN AV LGT+AVK A++++ L+ +E+DEVI+GNVLQ G Sbjct: 1 MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVGLNLSEIDEVIIGNVLQTG 60 Query: 74 LGQNVARQISIQAGIPMEVPSYTINKVCGSGLKSVQLAAQTILXXXXXXXXXXXXXNMSQ 133 LGQNVARQI+I AGIP VPSYT+NK+CGSGLKSVQLAAQ+I NMSQ Sbjct: 61 LGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSITSGENDVVIAGGTENMSQ 120 Query: 134 APYLLPTTRWGQRMGDGIVIDSMVHDGLTDAFNQYHMGITAENIAEKYNITREMQDKLAA 193 APY++PT R+G +MG+ ++DSM+ DGL DAFNQYHMGITAENIA K+ TREMQDKLA Sbjct: 121 APYIVPTARFGSKMGNITMVDSMLTDGLIDAFNQYHMGITAENIATKFEFTREMQDKLAL 180 Query: 194 ASQNKAEKAIKEGKFKEEIIPVEIPQRKGAPVVANTDEYPRMGVTAESLAELKPAFKKDG 253 SQNKAE AIK +FKEEI+PV++ R+G + DEYP++G+T E L++LKPAFKKDG Sbjct: 181 ESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDEYPKLGMTFEGLSKLKPAFKKDG 240 Query: 254 TVTAANASGLNDGAAILIVMSKSKAERLGLKPLVTIKAVECAGVAPEIMGTGPIPATKKA 313 TVTA NASG+NDGAA+LI+MS+ KA+ LG++PL IK+ AGV PE+MGTGPIPAT+KA Sbjct: 241 TVTAGNASGINDGAAMLILMSQQKADELGIRPLAKIKSYASAGVEPEVMGTGPIPATRKA 300 Query: 314 LATAGITVQDLDLVEANEAFASQALCVVNELGINMDMVNVNGGAIALGHPIGASGARILV 373 L AG+++ D+DL+EANEAFA+QAL V NEL I+ +NVNGGAIALGHPIGASGARILV Sbjct: 301 LKKAGLSINDIDLIEANEAFAAQALAVKNELQIDSSKLNVNGGAIALGHPIGASGARILV 360 Query: 374 TLIHEMERRKVQTGLATLCIGGGQGIAMIVER 405 TLI+EM++RKV+TGLATLCIGGGQGI+M+V R Sbjct: 361 TLIYEMQKRKVETGLATLCIGGGQGISMVVSR 392 >A8MFL5.1 A8MFL5_ALKOO Acetyl-CoA acetyltransferase EC=2.3.1.9 Length = 392 Score = 526 bits (1355), Expect = e-147, Method: Compositional matrix adjust. Identities = 254/392 (64%), Positives = 312/392 (79%) Query: 14 MKEVVIVSAVRTAVGSFGGVFKNVPAVTLGTVAVKGALAKINLDPAEVDEVILGNVLQAG 73 M+E+VI S VRTA+GSFGGV V AV +G +K AL++ LDP VDEV +G VLQAG Sbjct: 1 MREIVIASGVRTAIGSFGGVLSKVSAVDMGAAVIKEALSRAKLDPNLVDEVYMGCVLQAG 60 Query: 74 LGQNVARQISIQAGIPMEVPSYTINKVCGSGLKSVQLAAQTILXXXXXXXXXXXXXNMSQ 133 LGQ VARQ +I+AGIP EVP+ TIN +CGSGLK+V +AAQTI+ +MSQ Sbjct: 61 LGQGVARQAAIKAGIPQEVPATTINMLCGSGLKTVSMAAQTIIAGDNDIVVVGGTESMSQ 120 Query: 134 APYLLPTTRWGQRMGDGIVIDSMVHDGLTDAFNQYHMGITAENIAEKYNITREMQDKLAA 193 +PYL+P RWG RMG+ ++DSM++DGLTDAFN YHMGITAEN+A KY++TRE QD+ AA Sbjct: 121 SPYLVPHARWGARMGNSNMVDSMINDGLTDAFNNYHMGITAENLAAKYSLTREEQDEFAA 180 Query: 194 ASQNKAEKAIKEGKFKEEIIPVEIPQRKGAPVVANTDEYPRMGVTAESLAELKPAFKKDG 253 ASQNKAEKA+ EGKFK+EI+PVEIPQRKG P++ +TDEYP+ G+T ESL +LKP FKKDG Sbjct: 181 ASQNKAEKAMVEGKFKDEIVPVEIPQRKGDPIIVDTDEYPKAGMTVESLGKLKPVFKKDG 240 Query: 254 TVTAANASGLNDGAAILIVMSKSKAERLGLKPLVTIKAVECAGVAPEIMGTGPIPATKKA 313 TVTA NASG+NDGAA LI+M+K KAE LG++PL T+ + AGV P IMG GP+PAT+ A Sbjct: 241 TVTAGNASGINDGAAALILMTKEKAEALGIEPLATLVSYSSAGVDPAIMGIGPVPATEMA 300 Query: 314 LATAGITVQDLDLVEANEAFASQALCVVNELGINMDMVNVNGGAIALGHPIGASGARILV 373 L A + ++D+DL+EANEAFA+QAL V ELG + + VNVNGGAIALGHPIGASGARILV Sbjct: 301 LKKAKLRIEDMDLIEANEAFAAQALSVGKELGWDKEKVNVNGGAIALGHPIGASGARILV 360 Query: 374 TLIHEMERRKVQTGLATLCIGGGQGIAMIVER 405 TL++EM+RR Q GLATLCIGGG G A+IV+R Sbjct: 361 TLLYEMKRRSAQYGLATLCIGGGMGTAVIVKR 392 >Q898X5.1 Q898X5_CLOTE Acetyl-coA acetyltransferase EC=2.3.1.9 Length = 391 Score = 519 bits (1336), Expect = e-145, Method: Compositional matrix adjust. Identities = 254/392 (64%), Positives = 306/392 (78%), Gaps = 1/392 (0%) Query: 14 MKEVVIVSAVRTAVGSFGGVFKNVPAVTLGTVAVKGALAKINLDPAEVDEVILGNVLQAG 73 MKEVVIVSAVRTA+G FGG K+VPAV LG +K A+ + + P +DEVI+GNV+QAG Sbjct: 1 MKEVVIVSAVRTAMGKFGGTLKDVPAVELGATVIKEAINRAGIKPEIIDEVIMGNVIQAG 60 Query: 74 LGQNVARQISIQAGIPMEVPSYTINKVCGSGLKSVQLAAQTILXXXXXXXXXXXXXNMSQ 133 LGQ+ RQ +++AGIP+EVP++T+NKVCGSGL++V LAAQ I NMS Sbjct: 61 LGQSPGRQAAVKAGIPVEVPAFTLNKVCGSGLRAVGLAAQMIKAGDADVVIAGGMENMSA 120 Query: 134 APYLLPTTRWGQRMGDGIVIDSMVHDGLTDAFNQYHMGITAENIAEKYNITREMQDKLAA 193 APY+LP RWGQRM DG ++D+MV DGL ++FN YHMG+TAENIAEK+ +TREMQD+ A Sbjct: 121 APYVLPNARWGQRMFDGKMVDTMVKDGLWESFNDYHMGMTAENIAEKWELTREMQDEFAC 180 Query: 194 ASQNKAEKAIKEGKFKEEIIPVEIPQRKGAPVVANTDEYPRMGVTAESLAELKPAFKKDG 253 ASQNKAEKAIKEGKFK+EI+PV I RKG VV +TDE+PR G T ESLA+LKPAFKKDG Sbjct: 181 ASQNKAEKAIKEGKFKDEIVPVVIKTRKG-EVVFDTDEFPRFGATVESLAKLKPAFKKDG 239 Query: 254 TVTAANASGLNDGAAILIVMSKSKAERLGLKPLVTIKAVECAGVAPEIMGTGPIPATKKA 313 TVTA NASG+NDGAA L++MS KAE LGLKPL I + G+ P MG GP+ ATK A Sbjct: 240 TVTAGNASGINDGAAALVIMSAEKAEELGLKPLAKIASYGSKGLDPAYMGYGPVGATKVA 299 Query: 314 LATAGITVQDLDLVEANEAFASQALCVVNELGINMDMVNVNGGAIALGHPIGASGARILV 373 L AG V+DLDL+EANEAFASQ+L V +LG +M+ VNVNGGAIALGHP+G SGARILV Sbjct: 300 LEKAGWKVEDLDLIEANEAFASQSLAVAKDLGFDMEKVNVNGGAIALGHPVGCSGARILV 359 Query: 374 TLIHEMERRKVQTGLATLCIGGGQGIAMIVER 405 TL+HEM+RR + GLATLCIGGG G A++VER Sbjct: 360 TLLHEMQRRDSKKGLATLCIGGGMGTALLVER 391 >C4IED4.1 C4IED4_CLOBU Acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase) EC=2.3.1.9 Length = 393 Score = 518 bits (1335), Expect = e-145, Method: Compositional matrix adjust. Identities = 252/392 (64%), Positives = 304/392 (77%) Query: 14 MKEVVIVSAVRTAVGSFGGVFKNVPAVTLGTVAVKGALAKINLDPAEVDEVILGNVLQAG 73 MK+VVIVSAVRTA+GSFGG K+V AV LG +K A+ + + P V+EVI+GNV+QAG Sbjct: 1 MKDVVIVSAVRTALGSFGGTLKDVSAVDLGATVIKEAITRAGVKPELVEEVIMGNVIQAG 60 Query: 74 LGQNVARQISIQAGIPMEVPSYTINKVCGSGLKSVQLAAQTILXXXXXXXXXXXXXNMSQ 133 LGQN ARQ +I+AG+P EVP+ TINKVCGSGL+SV LAAQ I NMS Sbjct: 61 LGQNTARQATIKAGLPNEVPAMTINKVCGSGLRSVSLAAQMIKAGDADIIVAGGMENMSA 120 Query: 134 APYLLPTTRWGQRMGDGIVIDSMVHDGLTDAFNQYHMGITAENIAEKYNITREMQDKLAA 193 APY LPTTRWGQRM DG ++D+MV D L DAFN YHMG+TAENIA+++ IT+E QD +A Sbjct: 121 APYALPTTRWGQRMNDGKIVDTMVKDALWDAFNNYHMGVTAENIAKEWGITKEEQDAFSA 180 Query: 194 ASQNKAEKAIKEGKFKEEIIPVEIPQRKGAPVVANTDEYPRMGVTAESLAELKPAFKKDG 253 +SQ KAE+AIKEG+FK+EI+PV IPQRKG P V +TDE+PR G TAE+L +LKP F KDG Sbjct: 181 SSQQKAERAIKEGRFKDEIVPVVIPQRKGEPKVFDTDEFPRFGTTAETLGKLKPCFIKDG 240 Query: 254 TVTAANASGLNDGAAILIVMSKSKAERLGLKPLVTIKAVECAGVAPEIMGTGPIPATKKA 313 TVTA NASG+NDGAA ++MS KAE LG+KPL I + G+ P IMG GP ATKKA Sbjct: 241 TVTAGNASGINDGAAAFVIMSAEKAEELGIKPLAKILSYGSKGLDPAIMGYGPFHATKKA 300 Query: 314 LATAGITVQDLDLVEANEAFASQALCVVNELGINMDMVNVNGGAIALGHPIGASGARILV 373 L A +TV+DLDL+EANEAFA+Q+L V +L +MD VNVNGGAIALGHP+GASGARILV Sbjct: 301 LEVANLTVEDLDLIEANEAFAAQSLAVAKDLKFDMDKVNVNGGAIALGHPVGASGARILV 360 Query: 374 TLIHEMERRKVQTGLATLCIGGGQGIAMIVER 405 TL++EME+R + GLATLCIGGG G A+IVER Sbjct: 361 TLLYEMEKRDSKKGLATLCIGGGMGTAVIVER 392 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.315 0.132 0.365 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,100,619,334 Number of extensions: 81703501 Number of successful extensions: 301201 Number of sequences better than 1.0e-05: 5205 Number of HSP's gapped: 287671 Number of HSP's successfully gapped: 5612 Length of query: 407 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 269 Effective length of database: 1,760,596,133 Effective search space: 473600359777 Effective search space used: 473600359777 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 132 (55.5 bits)