BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0311.0005.p (227 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C0Z7K2.1 C0Z7K2_BREBN Two-component response regulator 246 1e-63 C0Z911.1 C0Z911_BREBN Two-component response regulator 238 4e-61 Q8ENG8.1 Q8ENG8_OCEIH Transcriptional regulator 217 6e-55 A8VQC0.1 A8VQC0_9BACI Response regulator receiver protein 216 2e-54 C1TI20.1 C1TI20_9FIRM Response regulator with CheY-like receiver... 211 4e-53 >C0Z7K2.1 C0Z7K2_BREBN Two-component response regulator Length = 229 Score = 246 bits (628), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 122/223 (54%), Positives = 156/223 (69%) Query: 2 MKSILIVEDEEAIARVLAAYLKKAGFQVTLAADGRTALEAFETAPPSLILLDINLPNMDG 61 MKSIL+VEDE IARV+ AYL+KAG++V A DG A+E F+ P L+LLD+ LP +G Sbjct: 1 MKSILLVEDELVIARVIKAYLQKAGYEVWSANDGLEAMELFDEKKPDLVLLDVMLPERNG 60 Query: 62 FELLGLIREKSSCPVIMLTARDSIXXXXXXXXXXXXXYMSKPFIPEEVVARVNAVLRRPS 121 +E+L IREKSSCPVI++TA Y++KPF+ +EVVARVNAVLRR Sbjct: 61 WEILQYIREKSSCPVIIMTALGQTDQKLKGLNQGADDYITKPFVADEVVARVNAVLRRSV 120 Query: 122 QWSDGSRKRHYGSLFIDFGARSVFLNGAEVSLSPRDLSVLLFLAERPNQICTRDQLLEHV 181 R +GSL I+F + V L+G E++ PRDLS+LLFLA+ PNQ TR+QL+E V Sbjct: 121 ILVKDQETRLFGSLKINFQSHHVTLHGLELTFHPRDLSLLLFLAQNPNQTFTREQLIEQV 180 Query: 182 WEMDYDGSDRAVDLSIKRLRQALSHWPAEEGEIRTLRGTGYQL 224 W MDY GSDRAVDL+IKR+R+ L +WP +EGEI+T RG GYQ Sbjct: 181 WGMDYGGSDRAVDLAIKRVRKTLENWPVQEGEIKTQRGVGYQF 223 >C0Z911.1 C0Z911_BREBN Two-component response regulator Length = 255 Score = 238 bits (606), Expect = 4e-61, Method: Compositional matrix adjust. Identities = 118/221 (53%), Positives = 155/221 (70%) Query: 4 SILIVEDEEAIARVLAAYLKKAGFQVTLAADGRTALEAFETAPPSLILLDINLPNMDGFE 63 +ILIVEDE I+RVL AYL+K F+V A +G A F++ P+L+LLD+ LP G+ Sbjct: 31 NILIVEDELPISRVLKAYLEKNNFRVEQAFNGEEAERKFDSHSPALVLLDVMLPGRSGWS 90 Query: 64 LLGLIREKSSCPVIMLTARDSIXXXXXXXXXXXXXYMSKPFIPEEVVARVNAVLRRPSQW 123 +L IR KSSCPVIMLTA I Y++KPFI +EVVARV+AVLRR Q Sbjct: 91 ILEYIRAKSSCPVIMLTALGQIDNKLAGLNKGADDYITKPFIADEVVARVHAVLRRSKQL 150 Query: 124 SDGSRKRHYGSLFIDFGARSVFLNGAEVSLSPRDLSVLLFLAERPNQICTRDQLLEHVWE 183 +G+ + +GSL +DF A SV L+G E++ +P+DL + LFLA+ NQ TR+QL+E VW Sbjct: 151 IEGNHVKQFGSLKVDFKAYSVMLHGIELAFTPKDLCLFLFLAQYKNQTFTREQLIEQVWG 210 Query: 184 MDYDGSDRAVDLSIKRLRQALSHWPAEEGEIRTLRGTGYQL 224 MDY+GSDRAVDL+IKR+R++L +WP EGEIRT RG GY+L Sbjct: 211 MDYEGSDRAVDLAIKRIRRSLENWPTSEGEIRTYRGLGYKL 251 >Q8ENG8.1 Q8ENG8_OCEIH Transcriptional regulator Length = 225 Score = 217 bits (553), Expect = 6e-55, Method: Compositional matrix adjust. Identities = 113/223 (50%), Positives = 145/223 (65%), Gaps = 2/223 (0%) Query: 2 MKSILIVEDEEAIARVLAAYLKKAGFQVTLAADGRTALEAFETAPPSLILLDINLPNMDG 61 MK ILI+EDE I++V+ YLKKAG+ V DG A++ F+ P L++LD+ LP +DG Sbjct: 1 MKKILIIEDEYPISQVIKVYLKKAGYDVEQVFDGSNAMDTFKHVEPDLVILDVMLPGVDG 60 Query: 62 FELLGLIREKSSCPVIMLTARDSIXXXXXXXXXXXXXYMSKPFIPEEVVARVNAVLRRPS 121 + LL IR K C VIMLTA + Y++KPF EE+VARV AVLRR Sbjct: 61 WTLLQDIRSK--CAVIMLTALGDVNYRLDGLNQGADDYIAKPFHGEELVARVQAVLRRIG 118 Query: 122 QWSDGSRKRHYGSLFIDFGARSVFLNGAEVSLSPRDLSVLLFLAERPNQICTRDQLLEHV 181 ++ S +G+L ID A V L G + L+PRDLS+LLF A+ PN+ TR+QLL+ + Sbjct: 119 NKNNNSNVIKFGTLEIDVVAHRVRLLGTIIELTPRDLSLLLFFADNPNRTFTREQLLDSI 178 Query: 182 WEMDYDGSDRAVDLSIKRLRQALSHWPAEEGEIRTLRGTGYQL 224 W DYDGSDRAVDLSIKRLR++L WP EGEI+T RG GYQ Sbjct: 179 WGWDYDGSDRAVDLSIKRLRKSLKDWPKSEGEIKTFRGLGYQF 221 >A8VQC0.1 A8VQC0_9BACI Response regulator receiver protein Length = 240 Score = 216 bits (549), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 109/224 (48%), Positives = 148/224 (66%), Gaps = 3/224 (1%) Query: 2 MKSILIVEDEEAIARVLAAYLKKAGFQVTLAADGRTALEAFETAPPSLILLDINLPNMDG 61 + +I+IVEDE AIARVL AY KK G+ + DG + F A P L+LLD+ LP DG Sbjct: 15 VTTIMIVEDEWAIARVLDAYCKKRGWHTVMVEDGHQVMAVFLDASPDLVLLDVMLPGRDG 74 Query: 62 FELLGLIREKSSCPVIMLTARDSIXXXXXXXXXXXXXYMSKPFIPEEVVARVNAVLRR-P 120 + +L IRE+S CPV+MLTA D + Y++KPF EEVVAR+ AVL+R P Sbjct: 75 WSILSEIRERSDCPVVMLTALDELDDRLKGFDGGADDYIAKPFHGEEVVARIAAVLKRQP 134 Query: 121 SQWSDGSRKRHYGSLFIDFGARSVFLNGAEVSLSPRDLSVLLFLAERPNQICTRDQLLEH 180 S+ + + +G L I G R V+L+G +V L+P+D ++L+ LA+ PN++ +RD+L+EH Sbjct: 135 SE--EKTDAMEFGDLEIRDGERRVYLSGKQVELTPKDTALLIHLAKHPNRVWSRDELIEH 192 Query: 181 VWEMDYDGSDRAVDLSIKRLRQALSHWPAEEGEIRTLRGTGYQL 224 VW DY GSDRAVDL++KR+RQAL W E G IRT+RG GY Sbjct: 193 VWGWDYTGSDRAVDLAVKRIRQALRKWDDEHGGIRTIRGEGYSF 236 >C1TI20.1 C1TI20_9FIRM Response regulator with CheY-like receiver domain and winged-helix DNA-binding domain Length = 227 Score = 211 bits (537), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 112/223 (50%), Positives = 151/223 (67%), Gaps = 1/223 (0%) Query: 2 MKSILIVEDEEAIARVLAAYLKKAGFQVTLAADGRTALEAFETAPPSLILLDINLPNMDG 61 M+++++VEDE IA VL AYL+KAGF +AADG AL F PSL+LLD+ LP DG Sbjct: 1 MQTLMVVEDETPIALVLRAYLEKAGFSTYIAADGEEALLKFSEINPSLLLLDLMLPGQDG 60 Query: 62 FELLGLIREKSSCPVIMLTARDSIXXXXXXXXXXXXXYMSKPFIPEEVVARVNAVLRRPS 121 +L IR+ S+CPVI++TAR ++ Y++KPF P+EVVARV AVLRRP+ Sbjct: 61 LSVLEKIRKTSTCPVIVITARGAVKDRLQGFHLGADDYIAKPFDPDEVVARVKAVLRRPA 120 Query: 122 QWSDGSRKRHYGSLFIDFGARSVFLNGAEVSLSPRDLSVLLFLAERPNQICTRDQLLEHV 181 + + +G L +DF + + L G +SL+ RD +L FL PNQ+ +R QLL++V Sbjct: 121 RIVEADLV-QFGHLTVDFTSCNAVLKGRNISLARRDWDLLSFLVRHPNQVFSRTQLLDYV 179 Query: 182 WEMDYDGSDRAVDLSIKRLRQALSHWPAEEGEIRTLRGTGYQL 224 W +DYDG DRAVD+++KRLRQAL WP+ EGEI T+RGTGY L Sbjct: 180 WGIDYDGGDRAVDVAVKRLRQALKDWPSSEGEIATVRGTGYML 222 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.136 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,242,739,571 Number of extensions: 44536775 Number of successful extensions: 216118 Number of sequences better than 1.0e-05: 24282 Number of HSP's gapped: 190230 Number of HSP's successfully gapped: 24365 Length of query: 227 Length of database: 3,060,696,203 Length adjustment: 131 Effective length of query: 96 Effective length of database: 1,826,543,238 Effective search space: 175348150848 Effective search space used: 175348150848 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 129 (54.3 bits)