BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0307.0083.p (593 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1D6F5.1 B1D6F5_9BACL Histidine kinase HAMP region domain protein 310 3e-82 A8VZY2.1 A8VZY2_9BACI Putative uncharacterized protein 268 2e-69 B3K5Y8.1 B3K5Y8_9BACI Histidine kinase internal region 242 9e-62 C4G5P0.1 C4G5P0_ABIDE Putative uncharacterized protein 186 7e-45 B1DBI1.1 B1DBI1_9BACL Integral membrane sensor signal transducti... 162 6e-38 >B1D6F5.1 B1D6F5_9BACL Histidine kinase HAMP region domain protein Length = 586 Score = 310 bits (794), Expect = 3e-82, Method: Compositional matrix adjust. Identities = 192/557 (34%), Positives = 312/557 (56%), Gaps = 27/557 (4%) Query: 37 AVTIWSYSSVKQNVSDKLARSNEETLTVIANQIGKTIDTISFASVYFSQLNNPDILESFR 96 AV++ SY+ +KQN+ +K SN L VI +I +TID ++FAS Y +N+ ++ S Sbjct: 32 AVSVISYTLLKQNMIEKFQISNNSMLNVIVGEIDRTIDDVTFASHYI--VNDSELRASLN 89 Query: 97 HLKDAESFADFETYVHYSRLNSMADILSMQSMDADLKMMIVNKQNRIIIGDS--YAAIFS 154 D + Y + R+ +++ + ++ + M +VN+ N I+ DS AAI Sbjct: 90 LFADTSRLNTYTDYTRFIRIKDSFSLITSKPLNNSIHMYLVNRANFILSPDSENLAAING 149 Query: 155 GLSERFVRESRKLDDKETTSLQWF-----PSGEEGAAPDYYYASRFIIDPSNHEKLATLF 209 L+ + ++ + LQ+ GE+G YY +R I D A L Sbjct: 150 KLAPLL----KNVNASKPVVLQYLGLLHDSPGEDGT----YYLARVIGDGGGKPYTAVLL 201 Query: 210 IGIPKSYFHNLLDTGNPDIIFSLADRSGEIIAVKGRSETSASGGMLV---SKVSIPKTGW 266 +GI SYF LL+ I +L D +G IA + +S +++++ KT W Sbjct: 202 VGIEGSYFEKLLERVEFGQI-ALFDGTGNRIAGSPNVQLQSSDSSDSVYRTQLTLDKTDW 260 Query: 267 LLSEEMPRKLIDSQINREFFVTLSVVGLFFLAFLILSMLWAGHINKPISLLRSSVKQYVG 326 L+ E + QI+R F++ + +V +F + F ++S+L+A ++ PI L+ +Q+ Sbjct: 261 KLAYETSEDSLFGQISRAFYIGIGLVLVFTVVFSVISLLFARKLHNPIQKLQRVARQFAL 320 Query: 327 GKRDVRIPVKGKDEVAVLSAAFNQMLDDINGLLHQVESEQEEKRLLELQALAAQIRPHFL 386 G RD+R+ VKG+D++A L +FNQMLD+I L+ +E EQE+KR++EL+AL QIRPHFL Sbjct: 321 GNRDMRLEVKGRDDIAELGHSFNQMLDEIEVLITNIEQEQEQKRVMELEALFMQIRPHFL 380 Query: 387 LNTLNSIKVSLLLVGDEPHGTMIDALMRLLRAYVHVDEPLKLAEECKVLGSYVQVMQIRN 446 +NTLNSIK SL+L D+ H ++D+LM LLRAY+ V+ P L EEC++LG YV +M++R+ Sbjct: 381 INTLNSIKCSLILSKDQVHSGIVDSLMNLLRAYLKVNTPSSLEEECRLLGYYVDIMKVRS 440 Query: 447 RLNIEFNYELGEGTELIELPRLLLQPIVENAIYHGFSSRPENPVIELRTALHYQKLEITI 506 + + + + +P+L+LQPIVENAI HG + E ++ + ++ + I Sbjct: 441 EMPLSLEARIEPELKGFVVPKLVLQPIVENAIVHGLDEKDELHIV-VHAYREQGRIYMAI 499 Query: 507 SDNGKGMPEEAIVRLNRRLLGAEDETPRQQDKG----VGLINTARRLQVLFGYQARLTAA 562 D+G GM EE +V LNRR+ + D P ++ VGL+N +RL++ +G A + Sbjct: 500 EDDGCGMEEEQLVWLNRRINVSSDMDPDAEEYAPYERVGLLNVIQRLKLTYG-SAEMKLR 558 Query: 563 SREGGGMSFTLYIPMVS 579 S GG++ L IP+ S Sbjct: 559 SNAAGGITVILAIPIPS 575 >A8VZY2.1 A8VZY2_9BACI Putative uncharacterized protein Length = 568 Score = 268 bits (684), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 164/545 (30%), Positives = 279/545 (51%), Gaps = 9/545 (1%) Query: 37 AVTIWSYSSVKQNVSDKLARSNEETLTVIANQIGKTIDTISFASVYFSQLNNPDILESFR 96 ++I +Y S KQN+++K+ NE + VIAN I K + + F+S + Q + + Sbjct: 31 TLSIITYQSDKQNIAEKMDFYNETIIDVIANDIDKLTNDLIFSSHFLIQ--DKGFKSAIA 88 Query: 97 HLKDAESFADFETYVHYSRLNSMADILSMQSMDADLKMMIVNKQNRIIIGDSYAAIFSGL 156 + D + + + + + ++++ ++ M +N I+ S + Sbjct: 89 EISDRDGIQSLTAFQQFEYIRERFLSMETRTLNQNISMFYLNDAGLIVTSRSMPLSQEDI 148 Query: 157 SERFVRESRKLDDKETTSLQWFPSGEEGAAPDYYYASRFIIDPSNHEKLATLFIGIPKSY 216 +++ S L+ + +Q+ +G+ +Y +R I + L I + Y Sbjct: 149 QRQWLSVSENLNLQTEMIIQYLGKSYDGSQ---HYFTRVIPRDLSTGNQGLLTIIVSDDY 205 Query: 217 FHNLLDTGNPDIIFSLADRSGEIIAVKGRSETSASGGMLVSKVSIPKTGWLLSEEMPRKL 276 F L + + I L D G +IA +T+A +L VS GW L E P + Sbjct: 206 FQQLFEPVSSGAI-RLNDDKGNMIA-GSEIDTAARDSLLERTVS--PFGWSLYYETPSQQ 261 Query: 277 IDSQINREFFVTLSVVGLFFLAFLILSMLWAGHINKPISLLRSSVKQYVGGKRDVRIPVK 336 I+ ++N+ F+ +L ++ F+ F++LSM A +++P+ L+ Q+ G R R V Sbjct: 262 INEELNQSFYSSLMIIFFLFVVFIMLSMKSARQLSRPVEELKLVADQFSQGNRGARFQVT 321 Query: 337 GKDEVAVLSAAFNQMLDDINGLLHQVESEQEEKRLLELQALAAQIRPHFLLNTLNSIKVS 396 G+DE+ L + N MLD+IN L+ ++E ++ +KR LEL AL QIRPHFL+NTLNSI+ S Sbjct: 322 GEDEIQSLGVSVNHMLDEINDLIERIEKKETQKRELELHALYEQIRPHFLMNTLNSIRCS 381 Query: 397 LLLVGDEPHGTMIDALMRLLRAYVHVDEPLKLAEECKVLGSYVQVMQIRNRLNIEFNYEL 456 L + DE H + +L LLR Y+ ++EP L E ++L Y+ +M++R + L Sbjct: 382 LEMEDDEFHSKKLYSLTMLLRKYLKINEPSTLRNEVELLTHYIDIMEMRKGRSYWLKAWL 441 Query: 457 GEGTELIELPRLLLQPIVENAIYHGFSSRPENPVIELRTALHYQKLEITISDNGKGMPEE 516 E T +E+P L LQPI+ENAI H F +P++E+R + + +T+ DNG G+ + Sbjct: 442 SEETHEVEIPFLTLQPIIENAILHAFEDPEHHPIMEIRAEIKDEWFHVTVWDNGSGISQS 501 Query: 517 AIVRLNRRLLGAEDETPRQQDKGVGLINTARRLQVLFGYQARLTAASREGGGMSFTLYIP 576 + +LNR L E +QQ +GL+N A RL++ F +A L S G G + + IP Sbjct: 502 KVDQLNRSLKDTRLEYSKQQGDSLGLVNIAERLKLTFSERATLVINSERGKGTTVQILIP 561 Query: 577 MVSGK 581 + K Sbjct: 562 VSDMK 566 >B3K5Y8.1 B3K5Y8_9BACI Histidine kinase internal region Length = 283 Score = 242 bits (617), Expect = 9e-62, Method: Compositional matrix adjust. Identities = 130/272 (47%), Positives = 178/272 (65%), Gaps = 2/272 (0%) Query: 306 WAGHINKPISLLRSSVKQYVGGKRDVRIPVKGKDEVAVLSAAFNQMLDDINGLLHQVESE 365 A ++ PI L+ V+Q+ G DVR+ VKGKD++A L N MLD + L+H +E E Sbjct: 1 MAKRLHSPIHKLQRVVRQFGMGNLDVRLEVKGKDDIAELGQTLNTMLDQLQRLIHDIEQE 60 Query: 366 QEEKRLLELQALAAQIRPHFLLNTLNSIKVSLLLVGDEPHGTMIDALMRLLRAYVHVDEP 425 QE+KR++EL+AL QIRPHFL+NTLNSIK SL+L D H +ID+LM LLRAY+ V+EP Sbjct: 61 QEQKRVMELEALFMQIRPHFLINTLNSIKCSLILTKDTLHSGIIDSLMSLLRAYLKVNEP 120 Query: 426 LKLAEECKVLGSYVQVMQIRNRLNIEFNYELGEGTELIELPRLLLQPIVENAIYHGFSSR 485 L EECK+LG YV +M+IRN + + +L TE + LP+L+LQPIVENAI HG Sbjct: 121 ATLREECKLLGHYVDIMKIRNEIPLHLEVDLEPETEGLILPKLILQPIVENAIVHGLVDH 180 Query: 486 PENPVIELRTALHYQKLEITISDNGKGMPEEAIVRLNRRLLGAEDETPRQQDKGVGLINT 545 + P IE+R+ + I I++NG G EE + LNRRL +E ++ VGL+N Sbjct: 181 -QTPRIEIRSRSSLDGIRIEITNNGTGADEEQLQCLNRRLRKPSEEQDGAYER-VGLMNV 238 Query: 546 ARRLQVLFGYQARLTAASREGGGMSFTLYIPM 577 +RL++ FG +A LT A+ GGMS TL +P+ Sbjct: 239 VQRLRLTFGPEASLTLANLPHGGMSVTLCLPL 270 >C4G5P0.1 C4G5P0_ABIDE Putative uncharacterized protein Length = 605 Score = 186 bits (471), Expect = 7e-45, Method: Compositional matrix adjust. Identities = 147/473 (31%), Positives = 235/473 (49%), Gaps = 34/473 (7%) Query: 146 GDSYAAIFSGLSERFVRESRKLDDKETTSLQWFPSGEEGAAPDYYY-ASRFIIDPSNHEK 204 GD+Y F+ L + ++ D + T + F Y + ASR I+D HE Sbjct: 139 GDNYD--FASLKNQLWYKTIYGKDDDITFISSFKDNFGSKKKQYVFSASRRILDAEGHE- 195 Query: 205 LATLFIGIPKSYFHNLLDTG-NPDIIFSLADRSGEIIA-----VKG-------------- 244 +ATL I I + Y ++ + N I + D +G II+ ++G Sbjct: 196 IATLLINIDEVYLSDIYKSALNGTNIIYIIDINGNIISHTDKNMRGMNFINVENFKKLYG 255 Query: 245 ----RSETSASGGMLVSKVSIPKTGWLLSEEMPRKLIDSQINREFFVTLSVVGLFFLAFL 300 R +SG L+S +TGW + EEMP + S + R + + ++G+ F L Sbjct: 256 ENEFRITKKSSGKYLISNYHDTQTGWTIIEEMPASFVFSDVYRAYIIIFIIMGICFFIAL 315 Query: 301 ILSMLWAGHINKPISLLRSSVKQYVGGKRDVRIPVKGKDEVAVLSAAFNQMLDDINGLLH 360 I+S L A ++KP+ L S+ Q G DV VKG DE+ +L +FN M +I LL Sbjct: 316 IISYLVARKVSKPLLKLCDSLNQVKEGNFDVVSDVKGYDEINLLKNSFNSMAQEIKKLLE 375 Query: 361 QVESEQEEKRLLELQALAAQIRPHFLLNTLNSIKVSLLLVGDEPHGTMIDALMRLLRAYV 420 ++ ++ KR +E L AQI PHFL NTL SIK + E MI A + L+ + Sbjct: 376 DIKIKEAYKRRIENDLLKAQINPHFLYNTLFSIKCLVETGQPEDVIKMISAFIDFLKMTL 435 Query: 421 HVDEPL-KLAEECKVLGSYVQVMQIRNRLNIEFNYELGEGTELIELPRLLLQPIVENAIY 479 D L L+EE + Y+ + QIR + F +E E T +P L+LQPIVENAI+ Sbjct: 436 RQDADLIYLSEEFAITEKYLILQQIRYGDMLSFEFEPDEETRDCMVPALILQPIVENAIF 495 Query: 480 HGFSSRPENPVIELRTALHYQKLEITISDNGKGMPEEAIVRLNRRLLGAEDETPRQQDKG 539 HG ++ E +I + + + +KL I++SD+G GM E + +++ ++ +++ Sbjct: 496 HGIEAKNEMGIIIITSKIQNEKLIISVSDDGIGMNSEVL----EQVISKCNKKEYTRNES 551 Query: 540 VGLINTARRLQVLFGYQARLTAASREGGGMSFTLYIPMVSGKEAIINDDCNAN 592 +G+ N + R++V FG + L S G + TL +P +S K+ I+D+ N N Sbjct: 552 IGIANVSGRIKVDFGDEYGLNIESEPDIGTTVTLELPAIS-KKTRISDNENFN 603 >B1DBI1.1 B1DBI1_9BACL Integral membrane sensor signal transduction histidine kinase Length = 605 Score = 162 bits (411), Expect = 6e-38, Method: Compositional matrix adjust. Identities = 102/292 (34%), Positives = 160/292 (54%), Gaps = 14/292 (4%) Query: 296 FLAFLILSMLWAGHINKPISLLRSSVKQYVGGKRDVRIPVKGKDEVAVLSAAFNQMLDDI 355 F+AFL++ +L + KP+ L G +VR ++G DE+ L F+QMLD I Sbjct: 310 FIAFLVVLLLLMRQLTKPLIKLGKVASSVQRGNLEVRSSIRGADEIGRLGFLFDQMLDRI 369 Query: 356 NGLLHQVESEQEEKRLLELQALAAQIRPHFLLNTLNSIKVSLLLVGDEPHGTMIDALMRL 415 ++ +V Q KR EL L AQI PHFL N LNSI++ ++ GD+ MI +L +L Sbjct: 370 KEMITEVSLTQARKRKAELAMLQAQINPHFLFNVLNSIRMKVMRSGDQDSAKMIASLSKL 429 Query: 416 LRAYVHVDE-PLKLAEECKVLGSYVQVMQIRNRLNIEFNYELGEGTELIELPRLLLQPIV 474 LR + DE + L EE ++L YV++M +R + + ++ + I +PR +LQP+V Sbjct: 430 LRMTISRDEDAILLHEEIELLTHYVELMNLRQKEEAQLLVDVDVTSFDIRVPRFILQPLV 489 Query: 475 ENAIYHGFSSRPENPVIELRTALHYQKLEITISDNGKGMPEEAIVRLNRRLL----GAED 530 ENA+ HGF+ I + + LE+++ D+G GM EE + RL RL+ GAE+ Sbjct: 490 ENALIHGFNQSA--GTIRITAERKDRFLELSVEDDGIGMDEEGLERLRARLMTAGAGAEE 547 Query: 531 --ETPRQQD---KGVGLINTARRLQVLFGYQARLTAASREGGGMSFTLYIPM 577 ET R + G+G+ N A R++++FG +T S G ++IP+ Sbjct: 548 VQETGRSKGPGMSGIGVANVAERMRIMFGDAFHITVDSDH--GTRIMMHIPI 597 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.136 0.385 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,273,546,594 Number of extensions: 132693580 Number of successful extensions: 383630 Number of sequences better than 1.0e-05: 2068 Number of HSP's gapped: 381887 Number of HSP's successfully gapped: 2070 Length of query: 593 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 451 Effective length of database: 1,722,912,073 Effective search space: 777033344923 Effective search space used: 777033344923 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)