BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0307.0073.p (396 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C2YN02.1 C2YN02_BACCE Histidine kinase 299 3e-79 C2QPB4.1 C2QPB4_BACCE Histidine kinase 298 4e-79 C3GXE5.1 C3GXE5_BACTU Histidine kinase 297 1e-78 A0RAM5.1 A0RAM5_BACAH Sensor histidine kinase EC=2.7.3.- 296 2e-78 C2SGB5.1 C2SGB5_BACCE Histidine kinase 296 3e-78 >C2YN02.1 C2YN02_BACCE Histidine kinase Length = 405 Score = 299 bits (766), Expect = 3e-79, Method: Compositional matrix adjust. Identities = 158/382 (41%), Positives = 248/382 (64%), Gaps = 8/382 (2%) Query: 13 LFASRLPTLIWVSIVYVGTIVLQFLREHLILESAVFTGLFTIHVLLHWNSYRVTYKKFWI 72 +F R ++W+++VY+ +++L+F L ++S FT + IH + HW + + ++ Sbjct: 18 VFIPRRFIVLWITLVYIASMLLEFRNNILSIDSFFFTIVIVIHTIFHWYASSLKNRQLLY 77 Query: 73 YFSVQAALIYLCAILMRDGYQAVLIGLLPILIAQTLS-YSFRVKRXXXXXXXXXXXXXXX 131 +F VQ +++L A ++ +G A+ +GL PILIAQ+L Y+ K Sbjct: 78 FFFVQLFIVFLAAFIVPNGSIAIFVGLTPILIAQSLYVYNNIFKVMAVFTLMYAIFCIAI 137 Query: 132 ALTVGDRDELIVFLPIFLLMLIVVLAYAILFFKQVQERLRIQSFLEDLREAHEKVEELTL 191 ++ G +++ + + +FLL+L +++ ++ + +Q R RIQS++++L A+ +VEELTL Sbjct: 138 SMNYG-VNKVAILISMFLLVLAIIIPFSYINKQQYDARNRIQSYIQELESAYMRVEELTL 196 Query: 192 ANERQRMARDLHDTLAQGVAGLIMRLEAADAHMSQNHPERAQEIIRQSMQQARRTLAEAR 251 ANERQRMARDLHDTLAQGVA LIM+LEA DAHM + + ER+QEI++Q+M +AR+TL +AR Sbjct: 197 ANERQRMARDLHDTLAQGVASLIMQLEAIDAHMQKGNIERSQEIMKQTMIRARQTLHDAR 256 Query: 252 RAIDNLRLKSAPEMDFKEAIADEIEHFREATGIVVSTDYRLNKRLSRLQMEHSLHIVKEC 311 ID+LR + F +A+ +E++ F EAT I V + +S L EH L+++ EC Sbjct: 257 LVIDDLRHTTN---SFNKAVEEEVQRFSEATSIQVRFTIQSPPHISSLVKEHCLYVISEC 313 Query: 312 LTNIARHAKADKVWVFVS--TQNDKLIIEIQDNGIGFKTDDIGKDAGHYGLLGIKERVRL 369 LTNIA+H++A V + V +KL IE+QDNG+GF T IGK+ GHYGL+G+ ERVRL Sbjct: 314 LTNIAKHSQATDVNLKVEYIDNPEKLTIEVQDNGMGFDTGSIGKNPGHYGLIGLNERVRL 373 Query: 370 IGGEIYVNSNS-EGTRVKLETP 390 I GEI++ S +GT+V ++ P Sbjct: 374 INGEIHILSEKMKGTKVCIQVP 395 >C2QPB4.1 C2QPB4_BACCE Histidine kinase Length = 405 Score = 298 bits (764), Expect = 4e-79, Method: Compositional matrix adjust. Identities = 157/382 (41%), Positives = 250/382 (65%), Gaps = 8/382 (2%) Query: 13 LFASRLPTLIWVSIVYVGTIVLQFLREHLILESAVFTGLFTIHVLLHWNSYRVTYKKFWI 72 +F R ++W+++VY+ +++L+F L ++S FT + IH + HW + + ++ Sbjct: 18 VFIPRRFIVLWITLVYIASMLLEFRNNILSMDSFFFTIIIVIHTIFHWYASSLKNRQLLY 77 Query: 73 YFSVQAALIYLCAILMRDGYQAVLIGLLPILIAQTLS-YSFRVKRXXXXXXXXXXXXXXX 131 +F VQ +++L A ++ +G A+ +GL PILIAQ+L Y+ K Sbjct: 78 FFFVQLFIVFLAAFIVPNGSIAIFVGLTPILIAQSLYVYNNIFKVMAVFTFMYAIFCTAI 137 Query: 132 ALTVGDRDELIVFLPIFLLMLIVVLAYAILFFKQVQERLRIQSFLEDLREAHEKVEELTL 191 ++ G +++ + + +FLL+L +++ ++ + +Q R RIQS++++L A+ +VEELTL Sbjct: 138 SMNYG-VNKVAILISMFLLVLAIIIPFSYINKQQYDARNRIQSYIQELESAYMRVEELTL 196 Query: 192 ANERQRMARDLHDTLAQGVAGLIMRLEAADAHMSQNHPERAQEIIRQSMQQARRTLAEAR 251 ANERQRMARDLHDTLAQGVA LIM+LEA DAHM + + R+QEI++Q+M +AR+TL +AR Sbjct: 197 ANERQRMARDLHDTLAQGVASLIMQLEAIDAHMQKGNTGRSQEIMKQTMIRARQTLHDAR 256 Query: 252 RAIDNLRLKSAPEMDFKEAIADEIEHFREATGIVVSTDYRLNKRLSRLQMEHSLHIVKEC 311 ID+LR + F +A+ +E++ F EAT I V + +SRL EH L++++EC Sbjct: 257 LVIDDLRHTTN---SFNKAVEEEVQRFSEATSIHVRFTIQSPPHISRLVKEHCLYVIREC 313 Query: 312 LTNIARHAKADKVWVFVSTQN--DKLIIEIQDNGIGFKTDDIGKDAGHYGLLGIKERVRL 369 LTNIA+H++A V + V + ++L IE++DNGIGF T IGK+ GHYGL+G+ ERVRL Sbjct: 314 LTNIAKHSQATDVHLKVEYSDSLERLTIEVEDNGIGFDTGYIGKNPGHYGLIGLNERVRL 373 Query: 370 IGGEIYVNSNS-EGTRVKLETP 390 I GEI++ S +GT+V ++ P Sbjct: 374 INGEIHILSEKVKGTKVCIQVP 395 >C3GXE5.1 C3GXE5_BACTU Histidine kinase Length = 405 Score = 297 bits (760), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 157/382 (41%), Positives = 249/382 (65%), Gaps = 8/382 (2%) Query: 13 LFASRLPTLIWVSIVYVGTIVLQFLREHLILESAVFTGLFTIHVLLHWNSYRVTYKKFWI 72 +F R ++W+++VY+ +++L+F L ++S FT + IH + HW + + ++ Sbjct: 18 VFIPRRFIVLWITLVYIASMLLEFRNNILSMDSFFFTIIIVIHTIFHWYASSLKNRQLLY 77 Query: 73 YFSVQAALIYLCAILMRDGYQAVLIGLLPILIAQTLS-YSFRVKRXXXXXXXXXXXXXXX 131 +F VQ +++L A ++ +G A+ +GL PILIAQ+L Y+ K Sbjct: 78 FFFVQLFIVFLAAFIVPNGSIAIFVGLTPILIAQSLYVYNNIFKVMAVFTLMYAIFCTAI 137 Query: 132 ALTVGDRDELIVFLPIFLLMLIVVLAYAILFFKQVQERLRIQSFLEDLREAHEKVEELTL 191 ++ G +++ + + +FLL+L +++ ++ + +Q R RIQS++++L A+ +VEELTL Sbjct: 138 SMNYG-VNKVAILISMFLLVLAIIIPFSYINKQQYDARNRIQSYIQELESAYMRVEELTL 196 Query: 192 ANERQRMARDLHDTLAQGVAGLIMRLEAADAHMSQNHPERAQEIIRQSMQQARRTLAEAR 251 ANERQRMARDLHDTLAQGVA LIM+LEA +AHM + + R+QEI++Q+M +AR+TL +AR Sbjct: 197 ANERQRMARDLHDTLAQGVASLIMQLEAIEAHMQKGNTGRSQEIMKQTMIRARQTLHDAR 256 Query: 252 RAIDNLRLKSAPEMDFKEAIADEIEHFREATGIVVSTDYRLNKRLSRLQMEHSLHIVKEC 311 ID+LR + F +A+ +E++ F EAT I V + +SRL EH L+++ EC Sbjct: 257 LVIDDLRHTTN---SFNKAVEEEVQRFSEATSIHVRFTIQSPPHISRLVKEHCLYVISEC 313 Query: 312 LTNIARHAKADKVWVFVSTQND--KLIIEIQDNGIGFKTDDIGKDAGHYGLLGIKERVRL 369 LTNIA+H++A V + V ++ KL IE++DNGIGF T IGK+ GHYGL+G+ ERVRL Sbjct: 314 LTNIAKHSQAKDVNLKVEYSDNLEKLTIEVEDNGIGFDTGYIGKNPGHYGLIGLNERVRL 373 Query: 370 IGGEIYVNSNS-EGTRVKLETP 390 I GEI++ S +GT+V ++ P Sbjct: 374 INGEIHILSEKMKGTKVCIQVP 395 >A0RAM5.1 A0RAM5_BACAH Sensor histidine kinase EC=2.7.3.- Length = 405 Score = 296 bits (758), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 157/382 (41%), Positives = 248/382 (64%), Gaps = 8/382 (2%) Query: 13 LFASRLPTLIWVSIVYVGTIVLQFLREHLILESAVFTGLFTIHVLLHWNSYRVTYKKFWI 72 +F R ++W+++VY+ +++L+F L ++S FT + IH + HW + + ++ Sbjct: 18 VFIPRRFIVLWITLVYIASMLLEFRNNILSMDSFFFTIIIVIHTIFHWYASSLKNRQLLY 77 Query: 73 YFSVQAALIYLCAILMRDGYQAVLIGLLPILIAQTLS-YSFRVKRXXXXXXXXXXXXXXX 131 +F VQ +++L A ++ +G A+ +GL PILIAQ+L Y+ K Sbjct: 78 FFFVQLFIVFLAAFIVPNGSIAIFVGLTPILIAQSLYVYNNIFKVMAVFTLMYAIFCIAI 137 Query: 132 ALTVGDRDELIVFLPIFLLMLIVVLAYAILFFKQVQERLRIQSFLEDLREAHEKVEELTL 191 ++ G +++ + + +FLL+L +++ ++ + +Q R RIQS++++L A+ +VEELTL Sbjct: 138 SMNYG-VNKVAILISMFLLVLAIIIPFSYINKQQYDARNRIQSYIQELESAYMRVEELTL 196 Query: 192 ANERQRMARDLHDTLAQGVAGLIMRLEAADAHMSQNHPERAQEIIRQSMQQARRTLAEAR 251 ANERQRMARDLHDTLAQGVA LIM+LEA DAHM + + R+QEI++Q+M +AR+TL +AR Sbjct: 197 ANERQRMARDLHDTLAQGVASLIMQLEAIDAHMQKGNTRRSQEIMKQTMIRARQTLHDAR 256 Query: 252 RAIDNLRLKSAPEMDFKEAIADEIEHFREATGIVVSTDYRLNKRLSRLQMEHSLHIVKEC 311 ID+LR + F +A+ +E++ F EAT I V + +S L EH L+++ EC Sbjct: 257 LVIDDLRHTTN---SFNKAVEEEVQRFSEATSIHVRFTIQSPPHISSLVKEHCLYVISEC 313 Query: 312 LTNIARHAKADKVWVFV--STQNDKLIIEIQDNGIGFKTDDIGKDAGHYGLLGIKERVRL 369 LTNIA+H++A V + V S ++L IE++DNGIGF T IGK+ GHYGL+G+ ERVRL Sbjct: 314 LTNIAKHSQATDVHLKVEYSGSLERLTIEVEDNGIGFDTGYIGKNPGHYGLIGLNERVRL 373 Query: 370 IGGEIYVNSNS-EGTRVKLETP 390 I GEI++ S +GT+V ++ P Sbjct: 374 INGEIHILSEKVKGTKVCIQVP 395 >C2SGB5.1 C2SGB5_BACCE Histidine kinase Length = 405 Score = 296 bits (757), Expect = 3e-78, Method: Compositional matrix adjust. Identities = 157/382 (41%), Positives = 246/382 (64%), Gaps = 8/382 (2%) Query: 13 LFASRLPTLIWVSIVYVGTIVLQFLREHLILESAVFTGLFTIHVLLHWNSYRVTYKKFWI 72 +F R ++W+++VY+ +++L+F ++S FT + IH + HW + + ++ Sbjct: 18 VFIPRRFIILWITLVYIASMLLEFRNNIFSMDSFFFTIVIVIHTIFHWYASSLKNRQLLY 77 Query: 73 YFSVQAALIYLCAILMRDGYQAVLIGLLPILIAQTLS-YSFRVKRXXXXXXXXXXXXXXX 131 +F VQ +++L A ++ +G A+ +GL PILIAQ+L Y+ K Sbjct: 78 FFFVQLFIVFLAAFIVPNGSIAIFVGLTPILIAQSLYVYNNIFKVMAVFTLMYAIFCTAI 137 Query: 132 ALTVGDRDELIVFLPIFLLMLIVVLAYAILFFKQVQERLRIQSFLEDLREAHEKVEELTL 191 ++ G ++L + + +FLL+L +++ ++ + +Q R RIQS++++L A+ +VEELTL Sbjct: 138 SINYG-VNKLAILISMFLLVLAIIIPFSYINKQQFDARNRIQSYIQELESAYMRVEELTL 196 Query: 192 ANERQRMARDLHDTLAQGVAGLIMRLEAADAHMSQNHPERAQEIIRQSMQQARRTLAEAR 251 ANERQRMARDLHDTLAQGVA LIM+LEA DAHM + + R+QEI++Q+M +AR+TL +AR Sbjct: 197 ANERQRMARDLHDTLAQGVASLIMQLEAIDAHMQKGNTGRSQEIMKQTMVRARQTLHDAR 256 Query: 252 RAIDNLRLKSAPEMDFKEAIADEIEHFREATGIVVSTDYRLNKRLSRLQMEHSLHIVKEC 311 ID+LR + F EA+ +E++ F EAT I V + +S + EH L+++ EC Sbjct: 257 LVIDDLRHTTN---SFNEAVKEEVQRFSEATSIHVRLTIQSPPYISSVVKEHCLYVISEC 313 Query: 312 LTNIARHAKADKVWVFVSTQND--KLIIEIQDNGIGFKTDDIGKDAGHYGLLGIKERVRL 369 LTNIA+H++A V + V +D K IE++DNGIGF T IGK+ GHYGL+G+ ERVRL Sbjct: 314 LTNIAKHSEATDVNLKVEYIDDLEKFTIEVEDNGIGFDTGYIGKNPGHYGLIGLNERVRL 373 Query: 370 IGGEIYVNSNS-EGTRVKLETP 390 I GEI++ S +GT+V ++ P Sbjct: 374 IKGEIHILSEKMKGTKVYIQVP 395 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.326 0.139 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,033,323,582 Number of extensions: 76356909 Number of successful extensions: 381332 Number of sequences better than 1.0e-05: 3655 Number of HSP's gapped: 376453 Number of HSP's successfully gapped: 3658 Length of query: 396 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 258 Effective length of database: 1,760,596,133 Effective search space: 454233802314 Effective search space used: 454233802314 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 132 (55.5 bits)