BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0307.0023.p (235 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KAW1.1 B3KAW1_9BACI Beta-lactamase domain protein 293 6e-78 B1DLR2.1 B1DLR2_9BACL Beta-lactamase domain protein 262 2e-68 Q1IY03.1 Q1IY03_DEIGD Beta-lactamase-like protein 136 2e-30 C1CVZ3.1 C1CVZ3_DEIDV Putative Metallo-beta-lactamase superfamil... 107 7e-22 A2U1B3.1 A2U1B3_9FLAO Metallo-beta-lactamase superfamily protein 85 5e-15 >B3KAW1.1 B3KAW1_9BACI Beta-lactamase domain protein Length = 225 Score = 293 bits (751), Expect = 6e-78, Method: Compositional matrix adjust. Identities = 140/223 (62%), Positives = 167/223 (74%) Query: 9 NARLRSSVLIDNGSDFWVIDCGPDWRRQMELQGRRGMHRLLVTHPHFDHIGGLPEWADSC 68 N RLRSSV+++ G ++IDCGPDWR ME G R M +L+TH HFDHIGGLPEW+D+C Sbjct: 2 NRRLRSSVMVECGETSFMIDCGPDWRGMMEGLGIRKMSDMLITHAHFDHIGGLPEWSDAC 61 Query: 69 RWMGYRGELYAPAEVIPVIQRQYPWLGGQIDMIPCDDGLELDGWQIRTWRVNHGKNGYSY 128 RW +G LYAPAEV+ I RQYPWL Q++M P DDG L GW+I W+VNHGKNGYSY Sbjct: 62 RWQREKGRLYAPAEVLDQIVRQYPWLPRQMEMTPVDDGFTLAGWEISCWKVNHGKNGYSY 121 Query: 129 AYRLEKDGYTWVYCPDSISLGPEETKHMHGADLLVLGTSFYYESAELSTRSVYDMTEAAE 188 AYR +KDGYTWVY DSI L EE K + G DLLVLGTSF +E+A+ TRSVYDM EAAE Sbjct: 122 AYRFQKDGYTWVYNSDSIHLSLEEKKPLKGVDLLVLGTSFVHETAKFETRSVYDMKEAAE 181 Query: 189 LLDIVQPVRAVYTHMSHDVDMRKDYILPGNVTLAVTGLKLRLG 231 LL V+P + VYTHMSHDVD+RK+ LP V +AV G+ +RL Sbjct: 182 LLAEVKPRQTVYTHMSHDVDVRKELPLPEGVRVAVAGMTVRLN 224 >B1DLR2.1 B1DLR2_9BACL Beta-lactamase domain protein Length = 260 Score = 262 bits (669), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 124/234 (52%), Positives = 165/234 (70%), Gaps = 5/234 (2%) Query: 2 EARSSGDNARLRSSVLIDNGSDF--WVIDCGPDWRRQMELQGRRGMHRLLVTHPHFDHIG 59 EAR+ G N R R+ V +D+ DF +IDCGPDW +QME G R ++R+LVTH HFDHIG Sbjct: 27 EARTGGANRRYRALVQLDS-PDFGTMMIDCGPDWGKQMESAGLRFVNRILVTHAHFDHIG 85 Query: 60 GLPEWADSCRWMGYRGELYAPAEVIPVIQRQYPWLGGQIDMIPCDDGLELDGWQIRTWRV 119 GLPEWAD+CRW+G +GE YAP+EVI I +++PWLG I +P D W++ W+V Sbjct: 86 GLPEWADACRWLGVKGEAYAPSEVIAEILQRFPWLGRNIAFVPIDQPCTFGNWEVLAWKV 145 Query: 120 NHGKNGYSYAYRLEK--DGYTWVYCPDSISLGPEETKHMHGADLLVLGTSFYYESAELST 177 NHGKNGY+YA+R ++ G +W YC DSI L E+ K + G DLLVLGTSFY E+ T Sbjct: 146 NHGKNGYAYAFRFDQKNSGTSWAYCSDSIGLTGEQQKPLFGLDLLVLGTSFYKENFRYET 205 Query: 178 RSVYDMTEAAELLDIVQPVRAVYTHMSHDVDMRKDYILPGNVTLAVTGLKLRLG 231 RSVYD+TEA ELL + P + ++THMSHD+D+RK Y +P A+TG+++ +G Sbjct: 206 RSVYDVTEALELLPVWGPKKTLFTHMSHDIDLRKTYPMPSYAEFALTGMEVSVG 259 >Q1IY03.1 Q1IY03_DEIGD Beta-lactamase-like protein Length = 267 Score = 136 bits (342), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 97/243 (39%), Positives = 139/243 (57%), Gaps = 16/243 (6%) Query: 2 EARSSGDNARLRSSVLIDNGS------DFWVIDCGPDWRRQM-ELQGRRGMHRLLVTHPH 54 EAR+SG N R RS+ L+ ++DCGPD Q+ L G +L++H H Sbjct: 28 EARTSGVNRRTRSAALVRGAEPSTGELQTLLLDCGPDLHAQLARLPGPLVPDAVLISHAH 87 Query: 55 FDHIGGLPEWADSCRWMGYRGELYAPAEVIPVIQRQYPWL---GGQIDMIPCDDGLELDG 111 DH+ GL + D + G R +YAPA VIP IQ ++ + + +P ++GLE+ G Sbjct: 88 NDHVLGLGDLLDYVGYAGERLHVYAPAAVIPDIQDRFRYAFRSAAPVWPLP-EEGLEVAG 146 Query: 112 WQIRTWRVNHGKNGYSYAYRLEKDGYTWVYCPDSISLGPEET-KHMHGADLLVLGTSFYY 170 ++R +RV HG NG+S+A+RL++ G+ Y D+I + E + + DLL+LGTSF Sbjct: 147 LRVRAFRVPHGANGHSHAFRLDRPGFAAAYVTDAIDIPAEVIGRWLTNLDLLILGTSFAD 206 Query: 171 ES-AELSTRSVYDMTEAAELLDIVQPVRAVY-THMSHDVDMRKDYILPGNVTLAVTGLKL 228 ES + RSVYD+ EA L Q VR V+ TH+SHDVD+R LP N + A GL+L Sbjct: 207 ESRVPHAGRSVYDVREALA-LPWAQAVRRVFLTHLSHDVDVRT-RPLPRNWSWAHDGLEL 264 Query: 229 RLG 231 LG Sbjct: 265 PLG 267 >C1CVZ3.1 C1CVZ3_DEIDV Putative Metallo-beta-lactamase superfamily protein Length = 263 Score = 107 bits (268), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 85/236 (36%), Positives = 123/236 (52%), Gaps = 10/236 (4%) Query: 2 EARSSGDNARLRSSVLIDNGSDFWVIDCGPDWRRQM-ELQGRRGMHRLLVTHPHFDHIGG 60 EAR+ G N R R+ +L+ + D D Q+ L L++H H DH+ G Sbjct: 30 EARAGGCNRRTRTGLLLRAAGQTVLFDASADLHAQLARLPEPVVPDAALISHAHNDHLLG 89 Query: 61 LPEWADSCRWMGYRGELYAPAEVIPVIQRQYPWL---GGQIDMIPCDDGLELDGWQIRTW 117 L + D + ++YAP +P IQ ++ + + ++P +DG+ L G +R + Sbjct: 90 LGDLLDYVHYARGSLQVYAPQTTLPDIQARFAYAFRASAPVRVLP-EDGVMLAGLSLRAF 148 Query: 118 RVNHGKNGYSYAYRLEKDGYTWVYCPDSISLGPEETKH--MHGADLLVLGTSFYYES-AE 174 +V HG NG S+A+RLE+ G+ V D+I + P E + DLLVLGTSF ES + Sbjct: 149 QVPHGANGQSHAFRLERPGWAAVIMTDAIDV-PSEIAGVWLQDLDLLVLGTSFADESGSP 207 Query: 175 LSTRSVYDMTEAAELLDIVQPVRAVYTHMSHDVDMRKDYILPGNVTLAVTGLKLRL 230 S RSVYD+ EA EL R V TH+SH VD R +LP +LA GL + L Sbjct: 208 RSGRSVYDIQEALELPWARAAGRVVLTHLSHGVDARA-VVLPEGWSLAYDGLSVTL 262 >A2U1B3.1 A2U1B3_9FLAO Metallo-beta-lactamase superfamily protein Length = 260 Score = 85.1 bits (209), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 63/232 (27%), Positives = 113/232 (48%), Gaps = 23/232 (9%) Query: 9 NARLRSSVLIDNGSDFWVIDCGPDWRRQMELQGRRGMHRLLVTHPHFDHIGGLPEWADSC 68 + RLRSS+LI +VIDCGPD+R+QM + + ++ +L TH H DH GL + C Sbjct: 38 DKRLRSSILISWDDVSYVIDCGPDFRQQMIREDVQLVNGVLFTHEHADHTAGLDDLRPYC 97 Query: 69 RWMGYRGELYAPAEVIPVIQRQYPWLGGQIDMIPCDDGLE----------LDGWQIRTWR 118 +G +Y A + +++++ ++ + + P +E ++ I Sbjct: 98 YKIG-EMPIYLNARTLKSLEQRFEYIFSKENRYPGAPSVEPTIVDKDPFFINDVTIIPLE 156 Query: 119 VNHGKNGYSYAYRLEKDGYTWVYCPDSISLGPEETKHMHGADLLVLGTSFYYESAELSTR 178 V HG+ + +YR++ + Y D + EE K + D+LV+ E Sbjct: 157 VMHGRLPVT-SYRIQD----FAYLTDVKFVVEEEKKKLQNLDVLVVNALRIEEHP----- 206 Query: 179 SVYDMTEAAELLDIVQPVRAVYTHMSHDVDMRKDYI--LPGNVTLAVTGLKL 228 + +++ EA + + ++P R +TH+SH + ++ LP NV LA GLK+ Sbjct: 207 THFNLQEALDFVAELKPKRTYFTHISHKLGFHEEVSNNLPENVFLAFDGLKI 258 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.139 0.455 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,545,154,165 Number of extensions: 66564286 Number of successful extensions: 138379 Number of sequences better than 1.0e-05: 111 Number of HSP's gapped: 138419 Number of HSP's successfully gapped: 111 Length of query: 235 Length of database: 3,060,696,203 Length adjustment: 131 Effective length of query: 104 Effective length of database: 1,826,543,238 Effective search space: 189960496752 Effective search space used: 189960496752 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 129 (54.3 bits)