BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0305.0036.p (602 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K5G1.1 B3K5G1_9BACI Histidine kinase internal region 624 e-177 Q8ES66.1 Q8ES66_OCEIH Hypothetical conserved protein 332 5e-89 Q2BFH5.1 Q2BFH5_9BACI Putative uncharacterized protein 311 9e-83 A9U8A1.1 A9U8A1_PHYPA Predicted protein (Fragment) 218 1e-54 B1DAE2.1 B1DAE2_9BACL Histidine kinase internal region 211 1e-52 >B3K5G1.1 B3K5G1_9BACI Histidine kinase internal region Length = 607 Score = 624 bits (1610), Expect = e-177, Method: Compositional matrix adjust. Identities = 326/593 (54%), Positives = 410/593 (69%), Gaps = 7/593 (1%) Query: 10 NFGLKRKALVIFLLFVILPTIGVGVIVQYKYNKVLREQFISSTRRNLDNVTSQLGEQTKM 69 N+GLK+KALVIFL FVILPT+GVGV+ Q K N+VLR QFI S++R+L+ VT+QL EQT M Sbjct: 10 NYGLKQKALVIFLFFVILPTLGVGVLAQDKLNEVLRGQFIQSSQRSLEIVTNQLEEQTAM 69 Query: 70 VEDIADYFILSPDMRNFLSSYPPLGNEQKAVYKRNIEDFLTFQLMSKSYIRSIVISGFNG 129 +EDIADY ILS DMR +L PP + + K+N+E FLTFQLMSK+YI+SI I+GFNG Sbjct: 70 IEDIADYLILSNDMRQYLRLDPPPESGRAEQLKQNLEGFLTFQLMSKNYIKSISITGFNG 129 Query: 130 NSIEMGEPFSGDEGVWEREAVARKGGIYWTEGYPLKSSWNGQVRVLSMIRILNSFSEITK 189 NSIEMGEP G+E W R A KGGI W+ GYP S W G+V ++S+ R+LNS+ EIT Sbjct: 130 NSIEMGEPIHGNEESWNRLADEHKGGIVWSNGYPSTSGWYGEVNLVSLFRVLNSYDEITL 189 Query: 190 PLGMLTIRLDEASIAAQLEKGVLAADYGSVFMVGGAGDLILESVNRLPGGYVPGPSQMHA 249 PL L IR+DEASI QL++G L D G VF+V G ++L S L G + Sbjct: 190 PLARLVIRMDEASILKQLQRG-LTRDEGMVFIVNAEGQIVLPSKELLSLDIGDGKAITDI 248 Query: 250 LTTGTNKLAAYTVAGKRYLTMYNQIENSKWKVVVMISEAKMAEEFRGVKIVMXXXXXXXX 309 +T GT + Y G+ YLT + ++EN+ W +V M+ +A + ++ RGV I+M Sbjct: 249 ITAGTMGSSTYRHDGEAYLTFHQRMENTDWTIVSMVPKAALDQDVRGVSILMQVILIGIL 308 Query: 310 XXXXXXXFGFHYTIIRPILRLKIETGRVAGGDFSARVPIDSQDEIAELNSKFNEMVMTIQ 369 GFHYTIIRPILRLKIET RV GDF+ARVPI S+DEI+ELN +FN+MV TIQ Sbjct: 309 LLGLSALIGFHYTIIRPILRLKIETNRVKLGDFNARVPIRSKDEISELNRRFNDMVSTIQ 368 Query: 370 QLIEHKYKXXXXXXXXXXXXMQNQMDPHFLYNTLDMIRWTARLEQAEQSSQLIEMLSRFF 429 +LIEHKYK +Q QMDPHFLYNTLDMIRWTARLE+A +SSQLIE+LSRF Sbjct: 369 ELIEHKYKLELRERESELRLLQEQMDPHFLYNTLDMIRWTARLEKAVESSQLIEILSRFL 428 Query: 430 RASVNNGSYQTTLGKEMEFVQAYLYLQQYRLGDKLSYSLHLEPGIEDAVTLKATIQPLVE 489 R+S+NNG Y+T+L KEMEFV++YLYLQQ RLG KL Y+L++E + +++TLKATIQPLVE Sbjct: 429 RSSLNNGHYETSLAKEMEFVRSYLYLQQRRLGRKLKYALYMEYDLANSLTLKATIQPLVE 488 Query: 490 NALKHAWDRSRPVNRIEVKAYTAGDEIRIEVTDNGKGMTXXXXXXXXXXLKPGPSERIAG 549 N LKH DR PV RI V AY DEI I+V DNG+GM L+ G AG Sbjct: 489 NFLKHGLDRREPVARITVIAYKREDEIWIDVQDNGRGMDDSTLEEVRESLRIGVQ---AG 545 Query: 550 HG-GALHNIHERLSIFFGQAFGLKIIYTSDEGTGIRIILPLQRTEREGGEDHE 601 GAL NIHERL +FFG+ +GL++I S +GT IR+ LP +E GGE ++ Sbjct: 546 RTRGALSNIHERLYLFFGERYGLEVIEASSQGTLIRLKLPY--SETYGGESYD 596 >Q8ES66.1 Q8ES66_OCEIH Hypothetical conserved protein Length = 577 Score = 332 bits (852), Expect = 5e-89, Method: Compositional matrix adjust. Identities = 205/586 (34%), Positives = 315/586 (53%), Gaps = 26/586 (4%) Query: 9 RNFGLKRKALVIFLLFVILPTIGVGVIVQYKYNKVLREQFISSTRRNLDNVTSQLGEQTK 68 + +GLKRK + F L +++P + V +++ Y+ N L+ Q I L L Sbjct: 2 KKWGLKRK-FITFFLALMIPILFVSLLIYYQTNVALKNQAIEEATERLSRNEQNLLTVFS 60 Query: 69 MVEDIADYFILSPDMRNFLSS-----YPPLGNEQKAVYKRNIEDFLTFQLMSKSYIRSIV 123 VE ++ Y I + R S Y P E V I+ + TFQL+S YI SI+ Sbjct: 61 TVEAMSSYMIYDRNFRKIFISQKDEMYQPDYQEAMEV----IKGYFTFQLISNPYINSIL 116 Query: 124 ISGFNGNSIEMGEPFSGDEGVWEREAVARKGGIYWTEGYPLKSSWNGQVRVLSMIRILNS 183 + G +G+ ++ GEP +G+E ++ A KG W+ Y +KS WN V+S+ RI+N Sbjct: 117 LEGRDGHLVKHGEPVTGNEQELDKVAKEAKGSPVWSNPYQVKSDWNEDKYVISLTRIIND 176 Query: 184 FSEITKPLGMLTIRLDEASIAAQLEKGVLAADYGSVFMVGGAGDLILESVNRLPGGYVPG 243 + I++ +G++ IRLD+A + Q+E +DY F+V G++IL L G P Sbjct: 177 MNNISEQIGIVRIRLDQAELYNQIEVRSQQSDY---FIVSDKGEVILHPDVDLVGKQFPD 233 Query: 244 PSQMHALTTGTNKLAAYTVAGKRYLTMYNQIENSKWKVVVMISEAKMAEEFRGVKIVMXX 303 + + G K +Y + + NQ+ N+ W V I E K+AE+ V+ ++ Sbjct: 234 SGLIKWIVDGVEKSYSYQDGESHLVVVKNQLTNTNWFSVTAIDEDKLAEDLTEVRALIGF 293 Query: 304 XXXXXXXXXXXXXFGFHYTIIRPILRLKIETGRVAGGDFSARVPIDSQDEIAELNSKFNE 363 F+++ I+ IL L +T +V G+ +A V +DS DEI +L +FN+ Sbjct: 294 LIGILFLAGLLFFTFFYHSNIKRILELTKQTKQVETGNLTASVHVDSNDEIGKLGYRFNK 353 Query: 364 MVMTIQQLIEHKYKXXXXXXXXXXXXMQNQMDPHFLYNTLDMIRWTARLEQAEQSSQLIE 423 MV TIQ+ I+ +Y+ +QNQ++PHFLYNTLDMIRW ARLE A ++SQLIE Sbjct: 354 MVKTIQKHIDTEYRLKIKQKESELKVLQNQINPHFLYNTLDMIRWNARLENAPETSQLIE 413 Query: 424 MLSRFFRASVNNGSYQTTLGKEMEFVQAYLYLQQYRLGDKLSYSLHLEPGIEDAVTLKAT 483 LS+ FR ++NNG +E+E+ QAYL LQ+ RLG+KL Y L +E ++ +K Sbjct: 414 RLSKIFRMNLNNGKSLVKFEEEVEYSQAYLELQKKRLGEKLDYQLVMEEQLKGYYVMKQM 473 Query: 484 IQPLVENALKHAWDRSRPVNRIEVKAYTAGDEIRIEVTDNGKGMTXXXXXXXXXXLKPGP 543 IQPL+EN+++H + I + Y ++ I+V DNG G K G Sbjct: 474 IQPLIENSIQHGFKNLPRQGIIRIHCYRDENQAVIDVIDNGWGFNEHK--------KNG- 524 Query: 544 SERIAGHGGALHNIHERLSIFFGQAFGLKIIYTSDEGTGIRIILPL 589 E AG+ AL N+++R+SI FG+ +GL I+ SDEG +R+ILPL Sbjct: 525 -ELRAGY--ALKNLNDRISIVFGKLYGLTIL-DSDEGAFLRMILPL 566 >Q2BFH5.1 Q2BFH5_9BACI Putative uncharacterized protein Length = 586 Score = 311 bits (798), Expect = 9e-83, Method: Compositional matrix adjust. Identities = 185/586 (31%), Positives = 306/586 (52%), Gaps = 21/586 (3%) Query: 8 PRNFGLKRKALVIFLLFVILPTIGVGVIVQYKYNKVLREQFISSTRRNLDNVTSQLGEQT 67 PRN+ LKRK + +F + + LPTI +GV++ Y+ ++Q + + L Sbjct: 2 PRNWNLKRKFVTVFFILISLPTIFLGVLIYYQATDAFKKQAEENILSRFEKNQETLNSII 61 Query: 68 KMVEDIADYFILSPDMRNFLSSYPPLGNEQKAVYKRNIEDFLTFQLMSKSYIRSIVISGF 127 + VE ++ Y I D R+F P ++ + + I + TFQLMS YI SI ++ Sbjct: 62 RDVESMSSYMIYDQDFRSFFK-LPKYRVQEIRLAEEEIRGYFTFQLMSYDYIDSIELTSR 120 Query: 128 NGNSIEMGEPFSG-DEGVWEREAVARKGGIYWTEGYPLKSSWNGQVRVLSMIRILNSFSE 186 S + G P SG E + +A+ G W+ Y ++S W G+ V+ M R++N Sbjct: 121 GDRSFQTGNPVSGVQEEPFVEKAIEANGSPSWSGSYEVESDWGGKHSVVLMTRVINDLRN 180 Query: 187 ITKPLGMLTIRLDEASIAAQLEKGVLAADYGSVFMVGGAGDLILESVNRLPGGYVPGPSQ 246 I++P+G+ IRLD + ++E V + G F++ GD+IL + G P Sbjct: 181 ISEPIGLAKIRLDTKKVFRRVE--VDPSQQGDYFILSNQGDVILHKDPSIVGKRFPDREL 238 Query: 247 MHALTTGTNKLAAYTVAGKRYLTMYNQIENSKWKVVVMISEAKMAEEFRGVKIVMXXXXX 306 + A+ Y G +L + +++N+ W V M+++ + V+ ++ Sbjct: 239 LDAILKSDEHTVRYKKDGNVFLIVKREVKNTNWLSVAMVNQDIVVGNLYNVRNLILFMIL 298 Query: 307 XXXXXXXXXXFGFHYTIIRPILRLKIETGRVAGGDFSARVPIDSQDEIAELNSKFNEMVM 366 GF+ +++PI+ L +T ++ G+FSA+V + SQDEI L +FN+MV Sbjct: 299 LLALLGGIAFIGFYLRLVKPIVELTGQTEQLEKGNFSAKVKVGSQDEIGILGMRFNQMVS 358 Query: 367 TIQQLIEHKYKXXXXXXXXXXXXMQNQMDPHFLYNTLDMIRWTARLEQAEQSSQLIEMLS 426 IQ+ I+ +Y+ +QNQ+DPHFLYNTLD+IRWTAR+E+A ++ LIE LS Sbjct: 359 KIQKYIDIEYRLKIKQKESELKALQNQIDPHFLYNTLDLIRWTARMEKAYETGGLIEKLS 418 Query: 427 RFFRASVNNGSYQTTLGKEMEFVQAYLYLQQYRLGD-KLSYSLHLEPGIEDAVTLKATIQ 485 R FR ++N G ++ KEM ++Q YL LQ+ R+G+ +L ++++ + I+DA +K +Q Sbjct: 419 RIFRMNLNMGKMWVSVEKEMIYLQNYLELQRSRMGEHRLQFAIYYDYEIKDAYLMKQILQ 478 Query: 486 PLVENALKHAWDRSRPVNRIEVKAYTAGDEIRIEVTDNGKGMTXXXXXXXXXXLKPGPSE 545 P+VEN++ H + +I ++ Y E+ I+V DNG G P E Sbjct: 479 PIVENSIAHGFRNLPRKGKITIRCYRREQEVWIDVIDNGWGF-------------PEQEE 525 Query: 546 RIAGH--GGALHNIHERLSIFFGQAFGLKIIYTSDEGTGIRIILPL 589 + G AL N+ ER+ I FG +FG++ S EG IR+ LP+ Sbjct: 526 AAENNQTGYALSNLKERIEIAFGGSFGIE-QEASREGAWIRVKLPV 570 >A9U8A1.1 A9U8A1_PHYPA Predicted protein (Fragment) Length = 296 Score = 218 bits (556), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 105/164 (64%), Positives = 127/164 (77%) Query: 364 MVMTIQQLIEHKYKXXXXXXXXXXXXMQNQMDPHFLYNTLDMIRWTARLEQAEQSSQLIE 423 MV+TI++LIEHKYK MQNQMDPHFLYNTLDMIRWTARLE+A +SSQLIE Sbjct: 1 MVVTIKELIEHKYKLELRQRESELKLMQNQMDPHFLYNTLDMIRWTARLEKASKSSQLIE 60 Query: 424 MLSRFFRASVNNGSYQTTLGKEMEFVQAYLYLQQYRLGDKLSYSLHLEPGIEDAVTLKAT 483 MLS+FFR+S++NG+Y+TTL KEMEFV++YL+LQQ RLGDKL Y+L +E GIE LKAT Sbjct: 61 MLSKFFRSSIDNGNYETTLYKEMEFVRSYLFLQQNRLGDKLQYALFMEAGIEQVPILKAT 120 Query: 484 IQPLVENALKHAWDRSRPVNRIEVKAYTAGDEIRIEVTDNGKGM 527 IQPLVEN +KH D+++P + VK Y EI I+V DNG GM Sbjct: 121 IQPLVENFIKHGLDKNKPRYIVHVKCYKNAGEIWIDVVDNGSGM 164 >B1DAE2.1 B1DAE2_9BACL Histidine kinase internal region Length = 627 Score = 211 bits (538), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 159/622 (25%), Positives = 291/622 (46%), Gaps = 47/622 (7%) Query: 10 NFGLKRKALVIFLLFVILPTIGVGVIVQYKYNKVLREQFISSTRRNLDNVTSQLGEQTKM 69 N+ ++ K ++ FLL ILP++ +G+++ + N ++ +Q T + +DNV L Sbjct: 14 NWSIRYKLILHFLLISILPSLVIGLLMGWIVNGIVEKQVNGHTMQLIDNVNKSLDYYAGN 73 Query: 70 VEDIADYFILSPDMRNFLSSYPPLGNEQKAVYKRNIEDFLTFQLMSKSYIRSIVISGFNG 129 +++I+ + ++PD++ FLS ++ Y+ + FL S + I++ NG Sbjct: 74 IQNISYFISMNPDIQAFLSEGKEAIDDDHEEYR--MSKFLQGFTSLYSEVAGIIVVRPNG 131 Query: 130 ----NSIEMGEPFSGDEGVWEREAVARKGGIYWTEGYPLKSSWNGQV-----RVLSMIRI 180 N + S + W +EAV KG I+ G+P + V+S++R Sbjct: 132 DYFSNEMYARTNDSLAKESWYQEAVEAKG-IFKIIGHPANRNVTTHSNYKDSEVVSVVRA 190 Query: 181 LNSFSEITKPLGMLTIRLDEASIAAQLEKGVLAADYGSVFMVGGAGDLILESVNRLPGGY 240 + + K LG++ I L + + A+ + V G + ++ G+ I Y Sbjct: 191 IQD-PDTQKTLGVVLIDL-KLRVIAETVRDVRLGKSGYLMVIDDKGESI----------Y 238 Query: 241 VPGPSQMHALTTG-----TNKLAAYTVAGKRYLTMYNQIENSKWKVVVMISEAKMAEEFR 295 P S++ +L + + A TV G++ +Y + + W V + + +E + Sbjct: 239 APKNSKIGSLGVALPGRQVSGMFAQTVGGQKLQFIYQKSSFTNWTTVGVFAVQDSVQEIK 298 Query: 296 GVKIVMXXXXXXXXXXXXXXXFGFHYTIIRPILRLKIETGRVAGGDFSARVPIDSQDEIA 355 + + + + ++I RPI +L +V G+ S R+P + +DEI Sbjct: 299 DINLYLVTFVFIVCMLGIAASYYLSHSISRPISQLASFMRKVEEGNMSIRIPEEREDEIG 358 Query: 356 ELNSKFNEMVMTIQQLIEHKYKXXXXXXXXXXXXMQNQMDPHFLYNTLDMIRWTARLEQA 415 L FN+M+ + +LI + +Q + PHFLYNTLD I+W AR + A Sbjct: 359 LLGRSFNKMLSQMTRLISQVWAEQRLKREAELRSLQAHIQPHFLYNTLDTIQWLARKDGA 418 Query: 416 EQSSQLIEMLSRFFRASVNNGSYQTTLGKEMEFVQAYLYLQQYRLGDKLSYSLHLEPGIE 475 +++++++E LS+ FR ++ G L E+E +++YL +QQ R DKL+Y++ ++ + Sbjct: 419 KEATEMVEALSKLFRIGLSKGQEMIPLTDEIEHIRSYLKIQQTRYKDKLNYNIEVDGSCD 478 Query: 476 DAVTLKATIQPLVENALKHAWDRSRPVNRIEVKAYTAGDEIRIEVTDNGKGMTXXXXXXX 535 D LK +QPLVENA+ H R I ++A + + + + + D+G GMT Sbjct: 479 DLFVLKLILQPLVENAIYHGIKERRGPGMITIRAIISEEILELVIQDDGAGMTEARLEAL 538 Query: 536 XXXLKPGPS------------ERIAGHGGA----LHNIHERLSIFFGQAFGLKIIYTSDE 579 L+ PS ER G G A L N+ ER+ + FG+ +G+ I Sbjct: 539 RAVLQAVPSVHEANAAQRAAEERQQGQGQAASYGLRNVQERIRLSFGETYGIAIASKEKA 598 Query: 580 GTGIRIILPLQRTEREGGEDHE 601 GT + I P+ R+G + H+ Sbjct: 599 GTTVIIKHPI--IHRKGQDTHD 618 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.137 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,297,238,751 Number of extensions: 129421749 Number of successful extensions: 318182 Number of sequences better than 1.0e-05: 2014 Number of HSP's gapped: 315308 Number of HSP's successfully gapped: 2015 Length of query: 602 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 460 Effective length of database: 1,722,912,073 Effective search space: 792539553580 Effective search space used: 792539553580 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)