BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0305.0011.p (765 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KFL9.1 B3KFL9_9BACI Histidine kinase HAMP region domain protein 525 e-147 B1DIU9.1 B1DIU9_9BACL Methyl-accepting chemotaxis sensory transd... 410 e-112 B3KA88.1 B3KA88_9BACI Histidine kinase HAMP region domain protein 310 5e-82 Q6VUH1.1 Q6VUH1_9BACL Methyl-accepting chemotaxis protein 171 2e-40 A4XM94.1 A4XM94_CALS8 Methyl-accepting chemotaxis sensory transd... 150 5e-34 >B3KFL9.1 B3KFL9_9BACI Histidine kinase HAMP region domain protein Length = 724 Score = 525 bits (1352), Expect = e-147, Method: Compositional matrix adjust. Identities = 321/718 (44%), Positives = 432/718 (60%), Gaps = 24/718 (3%) Query: 53 KEAASANGKGSALSFKGVLHGSVRQVKRVNPNKSVGVKXXXXXXXXXXXXXXXXXXXXYN 112 K ++++G +A SF + ++ ++ +NP KSVG++ YN Sbjct: 25 KTPSASSGIHTAKSFVSNMGTAISRMP-MNPAKSVGIRLFLIFLSAIVFFVIVLGYLSYN 83 Query: 113 KAKNTIKENVSEANRQTIIQTSEKLDITLKQYESLAMQLFFDPQMQNNLTDLVSAS-SSY 171 KAK+TI++N + N+QTIIQTSEK+DI L +YE+ Q+F+D ++Q L++ S Y Sbjct: 84 KAKDTIEKNAANGNQQTIIQTSEKIDIILDKYENAGRQIFYDIELQKLLSEYTDKKLSEY 143 Query: 172 DKFVATDAISKKLSSQTTTDSNIVAITLVPTSADYDIVSSGSSGMKLDNVRDQEWYKTAV 231 D F I KLS+Q T+DS I AI L+P+ + I+S+G S V +Q WY Sbjct: 144 DAFTVERTIRDKLSNQITSDSAIRAIYLIPSKGE-KIISAGQSSESSKTVLEQSWYA--- 199 Query: 232 ANAENYQSYYSKEAKSAQN--YWFPTAVAGDNGKNFAMVRSLKNLG-ANSGYVIMLELKN 288 E K W PT + F + RSL ++ S YV+M EL Sbjct: 200 ------------ELKEGDKKIMWLPT-MQNSGAPYFTIARSLGSMNDLTSTYVVMFELNA 246 Query: 289 SLLEEAFESVTLGDGSRIQLVSPDGTVVASSNPEEDGKASELGFIKESKINNKSQDA--K 346 S+L+ + + LG+ ++QL+SP+G VV+SS+ G + F KE + K+ D K Sbjct: 247 SVLDAQLKGINLGENGQLQLISPEGIVVSSSDSSIVGSETAWTFAKEFPADTKTDDVRTK 306 Query: 347 DANGEDVLAVYSPMVKADWKLAGIVPTGELVKAATPXXXXXXXXXXXXXXXXXXVGFVMV 406 D G +VLAVY+ + DWKL G V T EL K A+ +G MV Sbjct: 307 DEEGRNVLAVYNTLSTNDWKLVGSVQTSELTKDASSILVITLIVAAIDVIFAILIGIWMV 366 Query: 407 RMIARPLARLKDLMVEGAKGDLSVRTEYVSKDEIGELSASFNTMMERITELVAQTTDTAR 466 RMIARP+ +L LM EGAKG+L+VRT++ S+DEIG+LSASFN MME+IT LV QT++TA+ Sbjct: 367 RMIARPIGKLNLLMKEGAKGNLNVRTDHKSQDEIGQLSASFNDMMEQITGLVQQTSNTAQ 426 Query: 467 EVLETAGELGDASRXXXXXXXXXXXXXXXXXXXXXXLAQEAERGNELTDLIGTQMQSVIA 526 EVL TA EL DAS+ LA EAERG++LT+ I QMQ V+ Sbjct: 427 EVLRTAAELSDASKKTAISAKEIAVATEEIANGASSLAVEAERGSDLTNNISKQMQIVVT 486 Query: 527 ANAEMDEAARGVGEASGQGAKQLEELLTQTSRTGEMTTALVDRVNNLKETVSSVIKVLDV 586 AN EM ++AR V +S G K L +LL +T +T +MT +++ +V+ LKET SSV KVLDV Sbjct: 487 ANEEMGKSARHVESSSELGTKHLSDLLDKTHQTEDMTRSMMHKVDGLKETTSSVAKVLDV 546 Query: 587 MKNITQQTNILSLNATIXXXXXXXXXXXFMVVADEVRQLADQSKQSIAVVAGITDKIITE 646 ++NIT+QTNILSLNATI FMVVADE+RQLADQS+QSI +V+ ITD+I+ E Sbjct: 547 LQNITKQTNILSLNATIEAARAGAAGKGFMVVADEIRQLADQSRQSIDMVSQITDRIMAE 606 Query: 647 MNETVAVLSEVAPLFKQQMNSVKSTSEIFVSVQGQMDDFISSLESVTGAIDSLNHSQGVL 706 MNETV VL + PLFK QM++VK T++IFVSVQ QM +FI L+SVT +ID LN SQ VL Sbjct: 607 MNETVQVLLDANPLFKGQMDAVKETNDIFVSVQQQMVEFIDRLDSVTHSIDELNESQNVL 666 Query: 707 SDAMSNXXXXXXXXXXTSEEVASLSNEQQNVSDQLVALSGKLEGASTQLKDKLSLFTI 764 S+AMSN TSEEVASLS EQQ+VS QLV LS +LE S +LK+ LS F + Sbjct: 667 SEAMSNVSAVAEESSATSEEVASLSTEQQSVSSQLVNLSTQLENVSNELKETLSRFRL 724 >B1DIU9.1 B1DIU9_9BACL Methyl-accepting chemotaxis sensory transducer Length = 718 Score = 410 bits (1053), Expect = e-112, Method: Compositional matrix adjust. Identities = 253/692 (36%), Positives = 385/692 (55%), Gaps = 27/692 (3%) Query: 82 NPNKSVGVKXXXXXXXXXXXXXXXXXXXXYNKAKNTIKENVSEANRQTIIQTSEKLDITL 141 NP KSVG K Y+K K +++ VS A+ +TI+Q S LDI L Sbjct: 44 NPLKSVGTKLFLIIFVSIIACVLVVGQMAYSKTKTIVEDKVSSASFETIVQASANLDIIL 103 Query: 142 KQYESLAMQLFFDPQMQNNLTDLVSASSSYDKFVATDAISKKLSSQTTTDSNIVAITLVP 201 K YE L+MQ+ D + ++ L ++ ++D F A + ++L + ++ ++ L+P Sbjct: 104 KTYEDLSMQIMIDKEFHKLVSTLEDSTEAFDLFEAQKDLGERLQNAVMSNKAVIGAYLLP 163 Query: 202 TSADYDIVSSGSSGMKL-DNVRDQEWYKTAVANAENYQSYYSKEAKSAQNYWFPTAVAG- 259 ++ G++ + + ++ +W++ +K +K N W T G Sbjct: 164 LDDKLPTITYGTASVAVAPDLMKSDWFEK------------TKTSKGGVN-WIETQPTGF 210 Query: 260 ---DNGKNFAMVRSLKNLGANSG-YVIMLELKNSLLEEAFESVTLGDGSRIQLVSPDGTV 315 D + + R + N N+ Y++++EL ++E +E ++LG+GS+I LV D Sbjct: 211 GTKDKLPSIGLSRQMNNTTTNAASYILLIELNLEDIQEKYEDISLGEGSKIYLVDSDNKY 270 Query: 316 VASSNPEEDGKAS--ELGFIKESKINNKSQDAKDANGEDVLAVYSPMVKADWKLAGIVPT 373 +++ + GK + +L +E + KS + GE+VL+V+ + A W+L G +P Sbjct: 271 ISAPDNSLIGKGNVVKLNIDEEGSLKEKSTE-----GEEVLSVFKTLDTAGWRLVGTIPV 325 Query: 374 GELVKAATPXXXXXXXXXXXXXXXXXXVGFVMVRMIARPLARLKDLMVEGAKGDLSVRTE 433 ELVK A +G +++R IA PL +++LM EG +G+L+VR+ Sbjct: 326 NELVKDAGVINKMTWLIALVAMFIAIAIGMLVIRTIAMPLMAMRNLMNEGERGNLTVRSN 385 Query: 434 YVS-KDEIGELSASFNTMMERITELVAQTTDTAREVLETAGELGDASRXXXXXXXXXXXX 492 KDEIG+L SFN MM +IT L QTT +A EVL TAGEL D S+ Sbjct: 386 ITKRKDEIGQLGESFNKMMIQITALAKQTTQSADEVLSTAGELTDVSKKTAISAREISVA 445 Query: 493 XXXXXXXXXXLAQEAERGNELTDLIGTQMQSVIAANAEMDEAARGVGEASGQGAKQLEEL 552 LA EAERG++LT I QM+SV+ A M E+A V +AS QG + L Sbjct: 446 TEEIASGASSLAVEAERGSDLTGNINHQMKSVMDATGHMVESAGEVEKASQQGTAYMGLL 505 Query: 553 LTQTSRTGEMTTALVDRVNNLKETVSSVIKVLDVMKNITQQTNILSLNATIXXXXXXXXX 612 + +T T EMT ++V++V++LK + S++K+LDV+ N+T+QTNILSLNATI Sbjct: 506 IQKTGMTEEMTRSMVEKVDSLKLSTGSIVKILDVLNNLTKQTNILSLNATIEAARAGAAG 565 Query: 613 XXFMVVADEVRQLADQSKQSIAVVAGITDKIITEMNETVAVLSEVAPLFKQQMNSVKSTS 672 FMVVADE+R+LADQS+QSI VV IT+ I+T++ ETV VLS+ PLF++Q+ SVK + Sbjct: 566 KGFMVVADEIRKLADQSRQSIDVVGQITETIMTQIEETVTVLSDAYPLFQEQIGSVKEAN 625 Query: 673 EIFVSVQGQMDDFISSLESVTGAIDSLNHSQGVLSDAMSNXXXXXXXXXXTSEEVASLSN 732 ++F++VQ QM F+ L+SVT +I L+ SQ VL++AM N TSEEVASLS Sbjct: 626 QLFLTVQNQMGQFVQKLDSVTNSITMLDQSQAVLTEAMGNVSAVAQQSSATSEEVASLST 685 Query: 733 EQQNVSDQLVALSGKLEGASTQLKDKLSLFTI 764 EQ ++S+ LV LS KL+ S LK+ LS F I Sbjct: 686 EQLSISNGLVNLSEKLDAVSRGLKESLSRFKI 717 >B3KA88.1 B3KA88_9BACI Histidine kinase HAMP region domain protein Length = 678 Score = 310 bits (793), Expect = 5e-82, Method: Compositional matrix adjust. Identities = 213/664 (32%), Positives = 343/664 (51%), Gaps = 41/664 (6%) Query: 114 AKNTIKENVSEANRQTIIQTSEKLDITLKQYESLAMQLFFDPQMQNNLTDLVSASSS--- 170 +K+T+ + VSEA + Q ++KLD L QYE+ + Q D ++ DLV+ S++ Sbjct: 39 SKDTVMDQVSEATSGQMKQAADKLDFLLAQYEAASRQWALDTVLRE---DLVTVSTADIG 95 Query: 171 -YDKFVATDAISKKLSSQTTTDSNIVAITLVPTS--ADYDIVSSGSSGMKLDNVRDQEWY 227 DK A + I +KL+ ++D + + LV + A S+G SGM + + Sbjct: 96 IRDKTQAENRIREKLNGMASSDKRLQGMRLVAPNLQAQSSYNSTGYSGMSSSDGVKAKID 155 Query: 228 KTAVANAENYQSYYSKEAKSAQNYWFPTAVAG----DNGKNFAMVRSLKNL-GANSGYVI 282 + A+ E WFPT + G +N M R LKNL N+ YV+ Sbjct: 156 RIIQADGEPV--------------WFPTEIKGFMENENTATMTMGRLLKNLKNPNAQYVL 201 Query: 283 MLELKNSLLEEAFESVTLGDGSRIQLVSPDGTVVASSNPEEDGKASELGFIKESKINNKS 342 ++++K+ + E ++ +G+ ++++V+ D +V +P + + S I S Sbjct: 202 LMDVKDEAVGEVLANLKIGNNGQMRIVAEDNRIVHDMDPAQ--------LMLPSVITVPS 253 Query: 343 QDAKDA----NGEDVLAVYSPMVKADWKLAGIVPTGELVKAATPXXXXXXXXXXXXXXXX 398 DA++ ++ + VY+P+ A W + G P + V+A Sbjct: 254 -DAEEGGIYYTADEQMVVYTPLKTAPWHMVGFAPVSDFVQATDKLLAVTLAVIVAAVLVA 312 Query: 399 XXVGFVMVRMIARPLARLKDLMVEGAKGDLSVRTEYVSKDEIGELSASFNTMMERITELV 458 +G+ M+R + RPL ++ LM EG +G+L VRTE+ DEIG L SFN MM +I+ LV Sbjct: 313 VLIGYYMMRTVGRPLNQMCSLMEEGEQGNLRVRTEFRRADEIGRLGQSFNRMMGQISALV 372 Query: 459 AQTTDTAREVLETAGELGDASRXXXXXXXXXXXXXXXXXXXXXXLAQEAERGNELTDLIG 518 QT +A+EVL TA EL +ASR LA EAER N+L + IG Sbjct: 373 DQTNASAKEVLVTAEELAEASRGTSLTAGEIAAAMEQIAQGSGSLAMEAERENQLAENIG 432 Query: 519 TQMQSVIAANAEMDEAARGVGEASGQGAKQLEELLTQTSRTGEMTTALVDRVNNLKETVS 578 +M V N + AA V +G+GA+ ++ L+ +++R ++ A+V LK+ + Sbjct: 433 VRMSKVSDTNQVIAAAADRVLRVTGEGAQHMDSLVEKSTRINQVNRAIVQNAEKLKDNTA 492 Query: 579 SVIKVLDVMKNITQQTNILSLNATIXXXXXXXXXXXFMVVADEVRQLADQSKQSIAVVAG 638 S+ K+L++M IT QTN+LS+NATI FMVVA+EVR LAD+SK+SI V Sbjct: 493 SIHKILELMSEITHQTNVLSINATIEAARAGAAGSGFMVVANEVRSLADRSKESIQTVGA 552 Query: 639 ITDKIITEMNETVAVLSEVAPLFKQQMNSVKSTSEIFVSVQGQMDDFISSLESVTGAIDS 698 + I E+ +V L+ +PLF +Q++SV+ +F +V+ +MD ++ + T A++ Sbjct: 553 MILDIRHEVQGSVDALTSASPLFDEQLHSVQEAQGVFDNVRHEMDALLTEISESTHAVEV 612 Query: 699 LNHSQGVLSDAMSNXXXXXXXXXXTSEEVASLSNEQQNVSDQLVALSGKLEGASTQLKDK 758 L SQ L+D++S +EEVAS+S+EQ VS++LV LS +LE S L+ Sbjct: 613 LIDSQLALTDSISEASSIVQETSAATEEVASMSSEQFKVSEKLVGLSSRLEELSEGLRKS 672 Query: 759 LSLF 762 L +F Sbjct: 673 LVMF 676 >Q6VUH1.1 Q6VUH1_9BACL Methyl-accepting chemotaxis protein Length = 610 Score = 171 bits (434), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 134/503 (26%), Positives = 237/503 (47%), Gaps = 8/503 (1%) Query: 263 KNFAMVRSLKNLGANS--GYVIMLELKNSLLEEAFESVTLGDGSRIQLVSPDGTVVASSN 320 K FA R LK L N G+ ++LE+K +++ + L D + S DG V+ + Sbjct: 110 KVFAFGRPLKRLSDNKTVGF-LLLEVKADAIKQTLADLRLDDEGNSYIASADGKVLVA-- 166 Query: 321 PEEDGKASELGF-IKESKINNKSQDAKDANGEDVLAVYSPMVKADWKLAGIVPTGELVKA 379 EE ++L F +KE++ N Q+ NG + + A W++ + P +L++ Sbjct: 167 EEESLLGTKLSFGLKENEQENSWQEV--INGNKFIVTRAASAIAGWQVVSVYPVDKLLED 224 Query: 380 ATPXXXXXXXXXXXXXXXXXXVGFVMVRMIARPLARLKDLMVEGAKGDLSVRTEYVSKDE 439 + + R P+ +L+ +M G GDL+VR + KDE Sbjct: 225 MRQIRSEVIFIALVCSAIIIVLAYFSARRFTHPIEKLRMMMSHGEAGDLTVRADLAGKDE 284 Query: 440 IGELSASFNTMMERITELVAQTTDTAREVLETAGELGDASRXXXXXXXXXXXXXXXXXXX 499 + L SFN M+ +I + QT + A EVL T+ L ++S Sbjct: 285 LAALGGSFNQMIGKIRKQFIQTFEAADEVLGTSTHLSESSGKMSKYAKEIANATESIAKG 344 Query: 500 XXXLAQEAERGNELTDLIGTQMQSVIAANAEMDEAARGVGEASGQGAKQLEELLTQTSRT 559 A E+GN L + + ++ + ++ E + E S QG + + ++ + T Sbjct: 345 AEQQATALEKGNGLVLEMTSNVKQMTEDVQDLIEVSNQAQERSVQGTQHMTLMIGKNRDT 404 Query: 560 GEMTTALVDRVNNLKETVSSVIKVLDVMKNITQQTNILSLNATIXXXXXXXXXXXFMVVA 619 ++ + V+ L + + + +L++++NI++QTNILSLNATI FMV+A Sbjct: 405 AQIMKEISSHVSKLFDRLGEIDSILELIRNISKQTNILSLNATIEANRAGNAGKGFMVIA 464 Query: 620 DEVRQLADQSKQSIAVVAGITDKIITEMNETVAVLSEVAPLFKQQMNSVKSTSEIFVSVQ 679 EVR LA QS S+ + D I +M+ T L + P+ ++Q++SV+ + IF VQ Sbjct: 465 SEVRALAMQSGDSVTRIVQTLDNIRKDMDATKVALLKSGPIMEEQIHSVEQANLIFNQVQ 524 Query: 680 GQMDDFISSLESVTGAIDSLNHSQGVLSDAMSNXXXXXXXXXXTSEEVASLSNEQQNVSD 739 MD+ L + T ++ ++ SQ + + +S+ S++VAS + +QQ +++ Sbjct: 525 EGMDEANKRLSTFTMTMERMDQSQQQIMEFISDAAAVAEQSMAMSQQVASSAADQQQLTE 584 Query: 740 QLVALSGKLEGASTQLKDKLSLF 762 Q V S +LE S +L+ L+ F Sbjct: 585 QFVRWSVQLEQVSERLRVSLNHF 607 >A4XM94.1 A4XM94_CALS8 Methyl-accepting chemotaxis sensory transducer Length = 713 Score = 150 bits (379), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 130/564 (23%), Positives = 246/564 (43%), Gaps = 29/564 (5%) Query: 219 DNVRDQEWYKTAV---------ANAENYQSYYSKEAKSAQNYWFPTAVAGDNGKNFAMVR 269 D ++ WYK + ++AE + S + Y F G F + Sbjct: 161 DKLKKTPWYKKIIDAGGPILIESHAEEFDSVAKASNANLPEYAFSI------GMPFKDIA 214 Query: 270 SLKNLGANSGYVIMLELKNSLLEEAFESVTLG-DGSRIQLVSPDGTVVASSNPEEDGKAS 328 + + LG V++L++ + + + + +G + + G V+ S E K + Sbjct: 215 TNETLG-----VLLLDISKQWMRDTLQDTQISQNGGYMLALCSSGNVILPSEWENKMKLT 269 Query: 329 ---ELGFIK---ESKINNKSQDAKDAN--GEDVLAVYSPMVKADWKLAGIVPTGELVKAA 380 F+K ES+ K+ A G+ L YS + +W + G++P +LV+AA Sbjct: 270 PDKNTQFVKKILESQAAGKTNGAFHTAFAGKQFLITYSQVPDTNWTIVGMIPVSQLVEAA 329 Query: 381 TPXXXXXXXXXXXXXXXXXXVGFVMVRMIARPLARLKDLMVEGAKGDLSVRTEYVSKDEI 440 +G I R L R+ KGDL+V + DEI Sbjct: 330 RRLELIIIVLTILFTLIALVIGIYYALRIVRDLERVTKTFAVAEKGDLTVTLDIKRDDEI 389 Query: 441 GELSASFNTMMERITELVAQTTDTAREVLETAGELGDASRXXXXXXXXXXXXXXXXXXXX 500 G LS SFN M + I L+ + + ++EV L + Sbjct: 390 GLLSHSFNNMAKNIKALIEKGVNLSKEVSSAISTLTTIASETAAASNEVAKAISEIAEGA 449 Query: 501 XXLAQEAERGNELTDLIGTQMQSVIAANAEMDEAARGVGEASGQGAKQLEELLTQTSRTG 560 A+EA E G ++ +++++ ++M ++ V + S +G + + L T T Sbjct: 450 SNQAKEATNVVETVSKFGEKIDTIVSSASQMSTLSKSVSQLSNKGTEVVNTLNNVTHETV 509 Query: 561 EMTTALVDRVNNLKETVSSVIKVLDVMKNITQQTNILSLNATIXXXXXXXXXXXFMVVAD 620 +T ++ +N L E S+ K++ V+ I++QT +L+LNA+I F VVA Sbjct: 510 HITDTMIQTINQLAEYSRSIGKIIQVLSGISEQTKLLALNASIEAAKAGDAGRGFAVVAS 569 Query: 621 EVRQLADQSKQSIAVVAGITDKIITEMNETVAVLSEVAPLFKQQMNSVKSTSEIFVSVQG 680 E+R+LADQSK+S V + KI+ + V +V + QQ ++V++ + F +++ Sbjct: 570 EIRKLADQSKESTREVEDMIKKIVAQTKAAQEVADKVENVIDQQNSAVENVASAFSNIKS 629 Query: 681 QMDDFISSLESVTGAIDSLNHSQGVLSDAMSNXXXXXXXXXXTSEEVASLSNEQQNVSDQ 740 MD+ I +E++T +I +++ + + ++ N +S+EV++ + EQ ++ Sbjct: 630 AMDELIKGIENITESISAIDKEKDTIIHSIENISAISEETAASSQEVSASTQEQLAAIEE 689 Query: 741 LVALSGKLEGASTQLKDKLSLFTI 764 L A++ +L S L+ + +F + Sbjct: 690 LRAMTEQLNKLSQDLQAAMQIFKV 713 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.308 0.124 0.319 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,195,531,466 Number of extensions: 106661673 Number of successful extensions: 359016 Number of sequences better than 1.0e-05: 10359 Number of HSP's gapped: 344138 Number of HSP's successfully gapped: 10405 Length of query: 765 Length of database: 3,060,696,203 Length adjustment: 144 Effective length of query: 621 Effective length of database: 1,704,070,043 Effective search space: 1058227496703 Effective search space used: 1058227496703 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 135 (56.6 bits)