BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0301.0025.p (558 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DI42.1 B1DI42_9BACL Conserved repeat domain protein 332 6e-89 B1DI41.1 B1DI41_9BACL Conserved repeat domain protein 253 4e-65 B1DI40.1 B1DI40_9BACL Conserved repeat domain protein 244 1e-62 C2X9S1.1 C2X9S1_BACCE Cell surface protein 199 9e-49 C2PTW7.1 C2PTW7_BACCE Cell surface protein 197 2e-48 >B1DI42.1 B1DI42_9BACL Conserved repeat domain protein Length = 557 Score = 332 bits (851), Expect = 6e-89, Method: Compositional matrix adjust. Identities = 213/555 (38%), Positives = 309/555 (55%), Gaps = 23/555 (4%) Query: 13 NQSMVLYSSAAGADVITYSNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGNA 72 NQ+ V +SS + + YSNTV TP+VGP++T KSA + +T+ +T++ N GN Sbjct: 11 NQTHVRFSSGI-YNGVAYSNTVQTPLVGPIITANKSAFPQKLNRDQTVTFTILISNTGNR 69 Query: 73 PALTTLVDALPSGVSFVANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLP 132 PA L D +P+G+SF+ NSVL DG PLPG SP +GI LG + + +++ FQ IVV +P Sbjct: 70 PAAIQLQDLMPAGLSFIPNSVLLDGSPLPGASPQTGIPLGTIQIGSAIQVNFQAIVVFIP 129 Query: 133 PSLELGNRARAVYSFTTPEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTFVGDAVTF 192 S N A +Y+F+TP+GR V V SN+IT+ ++ Y+L + STP TF+GD V + Sbjct: 130 VSHVFQNEAAVLYTFSTPDGRVVSDSVLSNKITLEVVPYQLDAHASLSTPVTFLGDVVFY 189 Query: 193 TLRVRNEGTRLMSGILTTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTAD 252 L +RN+G M ++ LP+PEG F+PGSV+ G+ P DP GI + L PG Sbjct: 190 DLIIRNDGLLPMENVIVFLPLPEGFEFVPGSVVIDGVLVPWIDPASGIYIGYLAPGAVVT 249 Query: 253 ISFQVRVVSVPALTA---QAVVTYDADGDTDGTKSNTVTVAVIQSGLSVSLKVDKYSAAP 309 I VR+ ++PA T QA++ Y +G T +N + + + LSVSL VD A+ Sbjct: 250 IRVAVRLAAMPAETRVPFQAIIEYTVNGTVYRTLANLLILNITDPSLSVSLAVDPVKASA 309 Query: 310 GDRLGYRFTIRNSGKLAVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRA 369 RL Y T+ N AVDA L IP GT+F+ DS+ IDG+P++G +P G+PLGT+ A Sbjct: 310 CSRLTYTVTVNNENSFAVDAYLIRLIPQGTVFLPDSIMIDGVPRKGTNPASGLPLGTLLA 369 Query: 370 GSAAVVDLLVSIPAEADILQMPAIQNQGSVEYTFTLPDGRNVRERVRSNTVTTLLFSPVI 429 GS AV+ V+I Q+P NQ YT+ L DGR VR+ SN V T +F+ VI Sbjct: 370 GSTAVITYQVAIRTANS--QIP---NQVEAIYTYRLTDGRLVRQNAVSNPVVTDIFAAVI 424 Query: 430 SIEMTGEPPMVEPGGIAEFNIAVTNSGNYPAEVSVIQI-IPQGCTLETGKVT---ISVHT 485 S++ +P E F V N+GN A+V++ + P G L ++ IS T Sbjct: 425 SVQADAKPKYYEVERSVYFTAFVQNTGNLAADVTLYRTDYPNGFYLLDPQINDNQISSFT 484 Query: 486 VPESKYSGIVSLGVMDPGQTAQLSYLVRVHPGYMG-----SALQGSSTALYLYTIDGRRY 540 V E + LG++ GQT ++SY + V + + TA + YT + Sbjct: 485 VSEG-----LKLGLIASGQTIKVSYWIYVSDSEEMESESLTQVATRYTARFNYTYEDSTC 539 Query: 541 SGEARSNSYKLMIEE 555 SGE+ SN L ++ Sbjct: 540 SGESLSNELILPVDH 554 >B1DI41.1 B1DI41_9BACL Conserved repeat domain protein Length = 772 Score = 253 bits (646), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 171/512 (33%), Positives = 278/512 (54%), Gaps = 14/512 (2%) Query: 10 VVSNQSMVLYSSAAGADVITYSNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNE 69 V++NQS V ++S A + V T+SN V+TPV PVL VK+ T+A++G+T+ YT+ N Sbjct: 265 VLNNQSSVTFTSGAFSGV-TFSNIVSTPVYDPVLFAVKTGSTTNATVGDTVTYTIAIANT 323 Query: 70 GNAPALTTLVDALPSGVSFVANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVV 129 GN A L D +P+G FV NSV+ + P+PGV P +GI + V T ++F VI+ Sbjct: 324 GNYGADIILTDTIPTGTVFVPNSVIVNNQPVPGVDPSTGIPISNV--TTSATVSFSVIIQ 381 Query: 130 SLPPSLELGNRARAVYSFTTPEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTFVGDA 189 SLPP +L N+A A YS+T P+GR + G + SN + + + +++ + T VGD Sbjct: 382 SLPPGQQLTNQASATYSYTLPDGRTLNGSLTSNTLAIQVSVPNVAVAKSVPVTTAVVGDT 441 Query: 190 VTFTLRVRNEGTRLMSGILTTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGK 249 VT+T+ V N G ++ ++ P+P GA+F+ SV G+ P A P GI L + PG Sbjct: 442 VTYTIAVTNNGIENVNNVIVVDPIPTGAVFVANSVTVDGLPRPGASPAAGISLNTIAPGV 501 Query: 250 TADISFQVRVVSVPA---LTAQAVVTYDADGDTDGTKSNTVTVAVIQSGLSVSLKVDKYS 306 T+ ++F + + S+P L+ QA T+ + + SNTV + V Q+ + + + + Sbjct: 502 TSTVTFNLTITSLPTPAQLSNQASATFTSGAFSGSAFSNTVVLPVYQAIIGIQKTANTSN 561 Query: 307 AAPGDRLGYRFTIRNSGKLAVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGT 366 A GD + Y + N+G L + P+G FV +SV ++G+PQ G +P G +GT Sbjct: 562 ATVGDTVTYSLVVSNTGNLPAQVTITDPSPTGGAFVPNSVLVNGVPQPGANPSAGFSIGT 621 Query: 367 IRAGSAAVVDLLVSIPAEADILQMPAIQ---NQGSVEYTFTLPDGRNVRERVRSNTVTTL 423 + G + VV + E I +P Q N S +Y++ +PDGR + V SNT++ Sbjct: 622 VNPGQSVVVSVS----YEVVIQTLPPSQRLVNTASGDYSYLVPDGRTITGSVNSNTLSIP 677 Query: 424 LFSPVISIEMTGEPPMVEPGGIAEFNIAVTNSGNYPAE-VSVIQIIPQGCTLETGKVTIS 482 + SP +S+ + G + + I V+N G P V ++ +P G G VT++ Sbjct: 678 VSSPDVSVVKSTNAIDAVVGDVITYTILVSNLGISPVNSVILVDPVPTGTVFVPGSVTVN 737 Query: 483 VHTVPESKYSGIVSLGVMDPGQTAQLSYLVRV 514 + VP + +S+G + G TA +++ V+V Sbjct: 738 GNPVPTGNPNTGISIGTIANGATATVTFNVQV 769 Score = 242 bits (617), Expect = 9e-62, Method: Compositional matrix adjust. Identities = 185/552 (33%), Positives = 286/552 (51%), Gaps = 18/552 (3%) Query: 10 VVSNQSMVLYSSAAGADVITYSNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNE 69 V++N + V ++S A + +SNTV+TPV PV+++VKSA ++AS+G+T+ YTL+ N Sbjct: 9 VLNNTASVTFTSGAFSGT-AFSNTVSTPVDLPVISVVKSASTSNASVGQTVTYTLVVTNS 67 Query: 70 GNAPALTTLVDALPSGVSFVANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVV 129 GN PA T+ D +P+G SFV NS L G P+PG P SGI +G+VA V + F V++ Sbjct: 68 GNYPATVTITDNIPAGTSFVPNSALVGGAPVPGADPVSGIPVGSVAAGASVNVMFSVVIN 127 Query: 130 SLPPSLELGNRARAVYSFTTPEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTF--VG 187 SLP +L N A ++T P+GR SN +T + A +++ STP+T VG Sbjct: 128 SLPTPQQLSNTGTAGITYTLPDGRVFNQTAVSNTVTFPVSAPNATVV--KSTPSTALSVG 185 Query: 188 DAVTFTLRVRNEGTRLMSGILTTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDP 247 D VT+T V N G ++ +L T P+P G+ F+P S+ G P A+P G+ + + P Sbjct: 186 DTVTYTTTVTNSGIATITNVLFTDPIPAGSTFVPNSLTVDGATRPSANPATGVIIDSISP 245 Query: 248 GKTADISFQVRVVSVPA---LTAQAVVTYDADGDTDGTKSNTVTVAVIQSGLSVSLKVDK 304 G T I F V V S+P+ L Q+ VT+ + + T SN V+ V L Sbjct: 246 GATTTIVFNVLVTSLPSPAVLNNQSSVTFTSGAFSGVTFSNIVSTPVYDPVLFAVKTGST 305 Query: 305 YSAAPGDRLGYRFTIRNSGKLAVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPL 364 +A GD + Y I N+G D +L IP+GT+FV +SV ++ P GV P GIP+ Sbjct: 306 TNATVGDTVTYTIAIANTGNYGADIILTDTIPTGTVFVPNSVIVNNQPVPGVDPSTGIPI 365 Query: 365 GTIRAGSAAVVDLLVSIPAEADILQMPAIQNQGSVEYTFTLPDGRNVRERVRSNTVTTLL 424 + ++A V V I + Q+ NQ S Y++TLPDGR + + SNT+ + Sbjct: 366 SNVT--TSATVSFSVIIQSLPPGQQL---TNQASATYSYTLPDGRTLNGSLTSNTLAIQV 420 Query: 425 FSPVISIEMTGEPPMVEPGGIAEFNIAVTNSG-NYPAEVSVIQIIPQGCTLETGKVTISV 483 P +++ + G + IAVTN+G V V+ IP G VT+ Sbjct: 421 SVPNVAVAKSVPVTTAVVGDTVTYTIAVTNNGIENVNNVIVVDPIPTGAVFVANSVTVDG 480 Query: 484 HTVPESKYSGIVSLGVMDPGQTAQLSYLVRVHPGYMGSALQGSSTALYLYTIDGRRYSGE 543 P + + +SL + PG T+ +++ + + + L ++A T +SG Sbjct: 481 LPRPGASPAAGISLNTIAPGVTSTVTFNLTITSLPTPAQLSNQASA----TFTSGAFSGS 536 Query: 544 ARSNSYKLMIEE 555 A SN+ L + + Sbjct: 537 AFSNTVVLPVYQ 548 Score = 149 bits (376), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 91/254 (35%), Positives = 156/254 (61%), Gaps = 3/254 (1%) Query: 11 VSNQSMVLYSSAAGADVITYSNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEG 70 +SNQ+ ++S A + +SNTV PV ++ + K+A+ ++A++G+T+ Y+L+ N G Sbjct: 520 LSNQASATFTSGAFSGS-AFSNTVVLPVYQAIIGIQKTANTSNATVGDTVTYSLVVSNTG 578 Query: 71 NAPALTTLVDALPSGVSFVANSVLRDGVPLPGVSPFSGILLGAVAP--QTEVRIAFQVIV 128 N PA T+ D P+G +FV NSVL +GVP PG +P +G +G V P V ++++V++ Sbjct: 579 NLPAQVTITDPSPTGGAFVPNSVLVNGVPQPGANPSAGFSIGTVNPGQSVVVSVSYEVVI 638 Query: 129 VSLPPSLELGNRARAVYSFTTPEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTFVGD 188 +LPPS L N A YS+ P+GR + G V SN +++ + + +S++ +++ VGD Sbjct: 639 QTLPPSQRLVNTASGDYSYLVPDGRTITGSVNSNTLSIPVSSPDVSVVKSTNAIDAVVGD 698 Query: 189 AVTFTLRVRNEGTRLMSGILTTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPG 248 +T+T+ V N G ++ ++ PVP G +F+PGSV G P +P+ GI + + G Sbjct: 699 VITYTILVSNLGISPVNSVILVDPVPTGTVFVPGSVTVNGNPVPTGNPNTGISIGTIANG 758 Query: 249 KTADISFQVRVVSV 262 TA ++F V+VV++ Sbjct: 759 ATATVTFNVQVVTI 772 >B1DI40.1 B1DI40_9BACL Conserved repeat domain protein Length = 1433 Score = 244 bits (624), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 167/491 (34%), Positives = 266/491 (54%), Gaps = 17/491 (3%) Query: 31 SNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGNAPALTTLVDALPSGVSFVA 90 SN TPV PV+ L KSA T+A++G+T+ YT++ARN GN A TL D +P+G SF+ Sbjct: 727 SNNTTTPVYQPVIPLTKSASTTAATVGDTITYTILARNTGNLAATVTLFDNIPTGSSFIP 786 Query: 91 NSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTTP 150 SV +G P SP +GI +G++AP + + FQ ++ +LP L ++A + YS+T P Sbjct: 787 GSVTINGAASPAASPITGIAIGSLAPNAQTTVTFQTLLNTLPSPPVLNDQATSTYSYTLP 846 Query: 151 EGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGILTT 210 GR + G SN ++++ + +++ + S V D +T+T+ V N G ++ ++ + Sbjct: 847 SGRTLNGGSSSNTVSITASSPNVTVSKSVSDTAAAVQDVLTYTVLVTNNGIAPVTNVVLS 906 Query: 211 LPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVP---ALTA 267 P+P GA F+ GSV G S A+P+ GI L + G T ++FQ+RV S+P +L+ Sbjct: 907 DPIPPGATFVSGSVTINGTPSSLANPNAGISLGTISAGATVTVAFQIRVTSLPSSGSLSN 966 Query: 268 QAVVTYDADGDTDGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTIRNSGKLAV 327 A + + T + SNTVT V Q+ ++VS +A GD Y FT+ N+G A Sbjct: 967 AASAAFTSGAFTSSSTSNTVTTPVSQAVVAVSKSASTVNATVGDTFSYSFTLTNTGNAAA 1026 Query: 328 DAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDLLVSIPAEADI 387 +A L+ +PSG +F+ +SV ++G+P V P GIP+G I G +A V +V +I Sbjct: 1027 NATLSDTVPSGAVFIDNSVLVNGVPTPNVSPATGIPVGVIPVGGSATVSYVV------NI 1080 Query: 388 LQMPA---IQNQGSVEYTFTLPDGRNVRERVRSNTVTTLLFSPVISIEMTGEPPMVEPGG 444 + PA + NQ S YTFTL +GR + SNTVT + P +S+ + ++ G Sbjct: 1081 VSYPASRQLVNQASAAYTFTLANGRVINRSALSNTVTVQVALPNVSLVKSASRSVLVTGD 1140 Query: 445 IAEFNIAVTNSGNYPAEVSVIQI---IPQGCTLETGKVTISVHTVPESKYSGIVSLGVMD 501 F +TN+G A V+ I + + G V + + P + +SLG + Sbjct: 1141 TMTFTSVLTNNG--IAAVNNIVLRDPLQSNAAFVPGSVLVQNVSQPAASPDAGISLGSLA 1198 Query: 502 PGQTAQLSYLV 512 PG + +S+ V Sbjct: 1199 PGASVTVSFEV 1209 Score = 217 bits (553), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 141/423 (33%), Positives = 228/423 (53%), Gaps = 7/423 (1%) Query: 37 PVVGPVLTLVKSADHTSASLGETLVYTLIARNEGNAPALTTLVDALPSGVSFVANSVLRD 96 PV V+ + KSA +A++G+T Y+ N GNA A TL D +PSG F+ NSVL + Sbjct: 989 PVSQAVVAVSKSASTVNATVGDTFSYSFTLTNTGNAAANATLSDTVPSGAVFIDNSVLVN 1048 Query: 97 GVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTTPEGRHVE 156 GVP P VSP +GI +G + +++ V +VS P S +L N+A A Y+FT GR + Sbjct: 1049 GVPTPNVSPATGIPVGVIPVGGSATVSYVVNIVSYPASRQLVNQASAAYTFTLANGRVIN 1108 Query: 157 GEVFSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGILTTLPVPEG 216 SN +TV + +S++ ++S GD +TFT + N G ++ I+ P+ Sbjct: 1109 RSALSNTVTVQVALPNVSLVKSASRSVLVTGDTMTFTSVLTNNGIAAVNNIVLRDPLQSN 1168 Query: 217 AIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRV-VSVPA-LTAQAVVTYD 274 A F+PGSV+ + P A PD GI L L PG + +SF+V + +++P+ +T Q+ ++ Sbjct: 1169 AAFVPGSVLVQNVSQPAASPDAGISLGSLAPGASVTVSFEVIITMAIPSQITNQSTASFT 1228 Query: 275 ADGDTDGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTIRNSGKLAVDAMLAGA 334 + + + SNT V Q ++V +A GD + Y + N+G LA ++ Sbjct: 1229 SGTFSATSASNTTVTPVTQPQIAVVKSASTSNATIGDSIIYTLVVSNTGNLAAATIVTDN 1288 Query: 335 IPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDLLVSIPAEADILQMP-AI 393 IP+GT F +SV ++G+P G+ P GI +G++ G+ + V V + + L P ++ Sbjct: 1289 IPAGTTFTENSVIVNGMPMPGISPVTGIDIGSLAPGATSTVTFGVVVTS----LPTPQSL 1344 Query: 394 QNQGSVEYTFTLPDGRNVRERVRSNTVTTLLFSPVISIEMTGEPPMVEPGGIAEFNIAVT 453 N G+ YT+T DGR + V SNTVT + +P + + ++ +V G + VT Sbjct: 1345 SNTGTASYTYTPADGRTLTGSVNSNTVTFPVSAPNVGVALSANYTVVTVGDTITYTAVVT 1404 Query: 454 NSG 456 N+G Sbjct: 1405 NNG 1407 Score = 201 bits (511), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 150/513 (29%), Positives = 256/513 (49%), Gaps = 16/513 (3%) Query: 12 SNQSMVLYSSAAGADVITY---SNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARN 68 S ++ + AG D IT SNTV+ PV P++ + KS++ T+A++G T+ YTL+ N Sbjct: 449 SAKAAFTFQMVAGGDNITGVIPSNTVSVPVYSPIIGITKSSNRTTATVGSTVTYTLLVAN 508 Query: 69 EGNAPALTTLVDALPSGVSFVANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIV 128 GN A TL D +P+G SF+ + +G + G +P +G+ +G++A + F V V Sbjct: 509 TGNIAANVTLTDNIPTGSSFITGTFRVNGNVIAGANPAAGVAIGSIAAGATSTVTFIVQV 568 Query: 129 VSLPPSLELGNRARAVYSFTTPEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTFVGD 188 SLP + ++ A Y+FT P+GR + G SN +T+ + +++ + + VG+ Sbjct: 569 NSLPSPPQFVDQGTAAYTFTPPDGRTISGSAASNTLTLPVSLPSINLTKSVNVTDVAVGE 628 Query: 189 AVTFTLRVRNEGTRLMSGILTTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPG 248 +T+T + N G+ ++ + T +P GA F+ GSV GG + A+P GI + + Sbjct: 629 TLTYTSVIANTGSEAVTNVTLTDALPAGATFVTGSVTIGGTPNTTANPATGIAVGTVAAN 688 Query: 249 KTADISFQVRVVSVPA---LTAQAVVTYDADGDTDGTKSNTVTVAVIQSGLSVSLKVDKY 305 + ++ Q V S+PA L ++ V+Y + SN T V Q + ++ Sbjct: 689 SSVTVTLQALVSSMPASAQLVNRSNVSYTVGTFSGTAASNNTTTPVYQPVIPLTKSASTT 748 Query: 306 SAAPGDRLGYRFTIRNSGKLAVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLG 365 +A GD + Y RN+G LA L IP+G+ F+ SV I+G P GI +G Sbjct: 749 AATVGDTITYTILARNTGNLAATVTLFDNIPTGSSFIPGSVTINGAASPAASPITGIAIG 808 Query: 366 TIRAGSAAVV---DLLVSIPAEADILQMPAIQNQGSVEYTFTLPDGRNVRERVRSNTVTT 422 ++ + V LL ++P+ P + +Q + Y++TLP GR + SNTV+ Sbjct: 809 SLAPNAQTTVTFQTLLNTLPSP------PVLNDQATSTYSYTLPSGRTLNGGSSSNTVSI 862 Query: 423 LLFSPVISIEMTGEPPMVEPGGIAEFNIAVTNSGNYP-AEVSVIQIIPQGCTLETGKVTI 481 SP +++ + + + + VTN+G P V + IP G T +G VTI Sbjct: 863 TASSPNVTVSKSVSDTAAAVQDVLTYTVLVTNNGIAPVTNVVLSDPIPPGATFVSGSVTI 922 Query: 482 SVHTVPESKYSGIVSLGVMDPGQTAQLSYLVRV 514 + + + +SLG + G T +++ +RV Sbjct: 923 NGTPSSLANPNAGISLGTISAGATVTVAFQIRV 955 Score = 184 bits (468), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 166/558 (29%), Positives = 269/558 (48%), Gaps = 28/558 (5%) Query: 10 VVSNQS-MVLYSSAAGADVITYSNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARN 68 +V+NQS VL + +G + N + + P + +VKSA A +G+T+ YT+ N Sbjct: 317 LVNNQSSAVLTLTTSGDAYVVNGNAIQININSPTINVVKSASVAGAVVGDTITYTVTVSN 376 Query: 69 EGNAPALT-TLVDALPSGVSFVANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVI 127 G A A + L DALPSG++FV SV GV P +G LGA+ V + ++ + Sbjct: 377 TGTANAASVVLTDALPSGLTFVTGSVTVGGVARPTYDIIAGAPLGALNINGSVVVTYRAV 436 Query: 128 VVSLPPSLELGNRARAVYSF-TTPEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTFV 186 V SLP + L N A+A ++F G ++ G + SN ++V + + + I +S+ T V Sbjct: 437 VSSLPSTFLLPNSAKAAFTFQMVAGGDNITGVIPSNTVSVPVYSPIIGITKSSNRTTATV 496 Query: 187 GDAVTFTLRVRNEGTRLMSGILTTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLD 246 G VT+TL V N G + + + T +P G+ F+ G+ G A+P G+ + + Sbjct: 497 GSTVTYTLLVANTG-NIAANVTLTDNIPTGSSFITGTFRVNGNVIAGANPAAGVAIGSIA 555 Query: 247 PGKTADISFQVRVVSVPA---LTAQAVVTYD---ADGDT--DGTKSNTVTVAVIQSGLSV 298 G T+ ++F V+V S+P+ Q Y DG T SNT+T+ V +++ Sbjct: 556 AGATSTVTFIVQVNSLPSPPQFVDQGTAAYTFTPPDGRTISGSAASNTLTLPVSLPSINL 615 Query: 299 SLKVDKYSAAPGDRLGYRFTIRNSGKLAV-DAMLAGAIPSGTLFVWDSVHIDGIPQRGVH 357 + V+ A G+ L Y I N+G AV + L A+P+G FV SV I G P + Sbjct: 616 TKSVNVTDVAVGETLTYTSVIANTGSEAVTNVTLTDALPAGATFVTGSVTIGGTPNTTAN 675 Query: 358 PGEGIPLGTIRAGSAAVVD---LLVSIPAEADILQMPAIQNQGSVEYTFTLPDGRNVRER 414 P GI +GT+ A S+ V L+ S+PA A ++ N+ +V YT G Sbjct: 676 PATGIAVGTVAANSSVTVTLQALVSSMPASAQLV------NRSNVSYTVGTFSG-----T 724 Query: 415 VRSNTVTTLLFSPVISIEMTGEPPMVEPGGIAEFNIAVTNSGNYPAEVSVIQIIPQGCTL 474 SN TT ++ PVI + + G + I N+GN A V++ IP G + Sbjct: 725 AASNNTTTPVYQPVIPLTKSASTTAATVGDTITYTILARNTGNLAATVTLFDNIPTGSSF 784 Query: 475 ETGKVTISVHTVPESKYSGIVSLGVMDPGQTAQLSYLVRVHPGYMGSALQGSSTALYLYT 534 G VTI+ P + +++G + P +++ ++ L +T+ Y YT Sbjct: 785 IPGSVTINGAASPAASPITGIAIGSLAPNAQTTVTFQTLLNTLPSPPVLNDQATSTYSYT 844 Query: 535 I-DGRRYSGEARSNSYKL 551 + GR +G + SN+ + Sbjct: 845 LPSGRTLNGGSSSNTVSI 862 Score = 179 bits (454), Expect = 6e-43, Method: Compositional matrix adjust. Identities = 165/538 (30%), Positives = 255/538 (47%), Gaps = 31/538 (5%) Query: 31 SNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGN-APALTTLVDALPSGVSFV 89 SNT+ PV P + L KS + T ++GETL YT + N G+ A TL DALP+G +FV Sbjct: 601 SNTLTLPVSLPSINLTKSVNVTDVAVGETLTYTSVIANTGSEAVTNVTLTDALPAGATFV 660 Query: 90 ANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTT 149 SV G P +P +GI +G VA + V + Q +V S+P S +L NR+ Y+ T Sbjct: 661 TGSVTIGGTPNTTANPATGIAVGTVAANSSVTVTLQALVSSMPASAQLVNRSNVSYTVGT 720 Query: 150 PEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGILT 209 G SN T + + + ++ST VGD +T+T+ RN G L + + Sbjct: 721 -----FSGTAASNNTTTPVYQPVIPLTKSASTTAATVGDTITYTILARNTG-NLAATVTL 774 Query: 210 TLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVPA---LT 266 +P G+ F+PGSV G SP A P GI + L P ++FQ + ++P+ L Sbjct: 775 FDNIPTGSSFIPGSVTINGAASPAASPITGIAIGSLAPNAQTTVTFQTLLNTLPSPPVLN 834 Query: 267 AQAVVTYD---ADGDT--DGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTIRN 321 QA TY G T G+ SNTV++ ++VS V +AA D L Y + N Sbjct: 835 DQATSTYSYTLPSGRTLNGGSSSNTVSITASSPNVTVSKSVSDTAAAVQDVLTYTVLVTN 894 Query: 322 SGKLAV-DAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDL--- 377 +G V + +L+ IP G FV SV I+G P +P GI LGTI AG+ V Sbjct: 895 NGIAPVTNVVLSDPIPPGATFVSGSVTINGTPSSLANPNAGISLGTISAGATVTVAFQIR 954 Query: 378 LVSIPAEADILQMPAIQNQGSVEYTFTLPDGRNVRERVRSNTVTTLLFSPVISIEMTGEP 437 + S+P+ ++ N S +T SNTVTT + V+++ + Sbjct: 955 VTSLPSSG------SLSNAASAAFT-----SGAFTSSSTSNTVTTPVSQAVVAVSKSAST 1003 Query: 438 PMVEPGGIAEFNIAVTNSGNYPAEVSVIQIIPQGCTLETGKVTISVHTVPESKYSGIVSL 497 G ++ +TN+GN A ++ +P G V ++ P + + + Sbjct: 1004 VNATVGDTFSYSFTLTNTGNAAANATLSDTVPSGAVFIDNSVLVNGVPTPNVSPATGIPV 1063 Query: 498 GVMDPGQTAQLSYLVRVHPGYMGSALQGSSTALYLYTI-DGRRYSGEARSNSYKLMIE 554 GV+ G +A +SY+V + L ++A Y +T+ +GR + A SN+ + + Sbjct: 1064 GVIPVGGSATVSYVVNIVSYPASRQLVNQASAAYTFTLANGRVINRSALSNTVTVQVA 1121 Score = 159 bits (401), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 164/567 (28%), Positives = 262/567 (46%), Gaps = 40/567 (7%) Query: 9 PVVSNQSMVLYS----SAAGADVITYSNTVNTPVVGPVLTLVKSADHTSASLGETLVYTL 64 PV+++Q+ YS S + + SNTV+ P +T+ KS T+A++ + L YT+ Sbjct: 831 PVLNDQATSTYSYTLPSGRTLNGGSSSNTVSITASSPNVTVSKSVSDTAAAVQDVLTYTV 890 Query: 65 IARNEGNAPALTT-LVDALPSGVSFVANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIA 123 + N G AP L D +P G +FV+ SV +G P +P +GI LG ++ V +A Sbjct: 891 LVTNNGIAPVTNVVLSDPIPPGATFVSGSVTINGTPSSLANPNAGISLGTISAGATVTVA 950 Query: 124 FQVIVVSLPPSLELGNRARAVYS---FTTPEGRHVEGEVFSNQITVSLLAYKLSILLASS 180 FQ+ V SLP S L N A A ++ FT+ + S + +++ ++S Sbjct: 951 FQIRVTSLPSSGSLSNAASAAFTSGAFTSSSTSNTVTTPVSQAV--------VAVSKSAS 1002 Query: 181 TPTTFVGDAVTFTLRVRNEGTRLMSGILTTLPVPEGAIFLPGSVISGGIYSPDADPDKGI 240 T VGD +++ + N G + L+ VP GA+F+ SV+ G+ +P+ P GI Sbjct: 1003 TVNATVGDTFSYSFTLTNTGNAAANATLSDT-VPSGAVFIDNSVLVNGVPTPNVSPATGI 1061 Query: 241 PLPPLDPGKTADISFQVRVVSVPA---LTAQAVVTYD---ADGD--TDGTKSNTVTVAVI 292 P+ + G +A +S+ V +VS PA L QA Y A+G SNTVTV V Sbjct: 1062 PVGVIPVGGSATVSYVVNIVSYPASRQLVNQASAAYTFTLANGRVINRSALSNTVTVQVA 1121 Query: 293 QSGLSVSLKVDKYSAAPGDRLGYRFTIRNSGKLAVDAM-LAGAIPSGTLFVWDSVHIDGI 351 +S+ + GD + + + N+G AV+ + L + S FV SV + + Sbjct: 1122 LPNVSLVKSASRSVLVTGDTMTFTSVLTNNGIAAVNNIVLRDPLQSNAAFVPGSVLVQNV 1181 Query: 352 PQRGVHPGEGIPLGTIRAGSAAVVDLLVSIPAEADILQMPA-IQNQGSVEYTFTLPDGRN 410 Q P GI LG++ G++ V V I + +P+ I NQ + +T Sbjct: 1182 SQPAASPDAGISLGSLAPGASVTVSFEVII-----TMAIPSQITNQSTASFT-----SGT 1231 Query: 411 VRERVRSNTVTTLLFSPVISIEMTGEPPMVEPGGIAEFNIAVTNSGNYPAEVSVIQIIPQ 470 SNT T + P I++ + G + + V+N+GN A V IP Sbjct: 1232 FSATSASNTTVTPVTQPQIAVVKSASTSNATIGDSIIYTLVVSNTGNLAAATIVTDNIPA 1291 Query: 471 GCTLETGKVTISVHTVPE-SKYSGIVSLGVMDPGQTAQLSYLVRVHPGYMGSALQGSSTA 529 G T V ++ +P S +GI +G + PG T+ +++ V V +L + TA Sbjct: 1292 GTTFTENSVIVNGMPMPGISPVTGI-DIGSLAPGATSTVTFGVVVTSLPTPQSLSNTGTA 1350 Query: 530 LYLYT-IDGRRYSGEARSNSYKLMIEE 555 Y YT DGR +G SN+ + Sbjct: 1351 SYTYTPADGRTLTGSVNSNTVTFPVSA 1377 Score = 138 bits (347), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 76/212 (35%), Positives = 124/212 (58%), Gaps = 1/212 (0%) Query: 11 VSNQSMVLYSSAAGADVITYSNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEG 70 ++NQS ++S + SNT TPV P + +VKSA ++A++G++++YTL+ N G Sbjct: 1219 ITNQSTASFTSGT-FSATSASNTTVTPVTQPQIAVVKSASTSNATIGDSIIYTLVVSNTG 1277 Query: 71 NAPALTTLVDALPSGVSFVANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVS 130 N A T + D +P+G +F NSV+ +G+P+PG+SP +GI +G++AP + F V+V S Sbjct: 1278 NLAAATIVTDNIPAGTTFTENSVIVNGMPMPGISPVTGIDIGSLAPGATSTVTFGVVVTS 1337 Query: 131 LPPSLELGNRARAVYSFTTPEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTFVGDAV 190 LP L N A Y++T +GR + G V SN +T + A + + L+++ VGD + Sbjct: 1338 LPTPQSLSNTGTASYTYTPADGRTLTGSVNSNTVTFPVSAPNVGVALSANYTVVTVGDTI 1397 Query: 191 TFTLRVRNEGTRLMSGILTTLPVPEGAIFLPG 222 T+T V N G ++ + T P P G + G Sbjct: 1398 TYTAVVTNNGIETVNNVQYTDPAPCGNLLYSG 1429 Score = 91.7 bits (226), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 79/296 (26%), Positives = 135/296 (45%), Gaps = 16/296 (5%) Query: 267 AQAVVTYDADGDTDGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTIRNSGKL- 325 + AV+T GD N + + + ++V A GD + Y T+ N+G Sbjct: 322 SSAVLTLTTSGDAYVVNGNAIQININSPTINVVKSASVAGAVVGDTITYTVTVSNTGTAN 381 Query: 326 AVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDLLVSIPAEA 385 A +L A+PSG FV SV + G+ + G PLG + + VV + + Sbjct: 382 AASVVLTDALPSGLTFVTGSVTVGGVARPTYDIIAGAPLGALNINGSVVVTYRAVVSSLP 441 Query: 386 DILQMPAIQNQGSVEYTFTL-PDGRNVRERVRSNTVTTLLFSPVISIEMTGEPPMVEPGG 444 +P N +TF + G N+ + SNTV+ ++SP+I I + G Sbjct: 442 STFLLP---NSAKAAFTFQMVAGGDNITGVIPSNTVSVPVYSPIIGITKSSNRTTATVGS 498 Query: 445 IAEFNIAVTNSGNYPAEVSVIQIIPQGCTLETGKVTISVHTVPESKYSGIVSLGVMDPGQ 504 + + V N+GN A V++ IP G + TG ++ + + + + V++G + G Sbjct: 499 TVTYTLLVANTGNIAANVTLTDNIPTGSSFITGTFRVNGNVIAGANPAAGVAIGSIAAGA 558 Query: 505 TAQLSYLVRVH-----PGYMGSALQGSSTALYLYTI-DGRRYSGEARSNSYKLMIE 554 T+ ++++V+V+ P ++ QG TA Y +T DGR SG A SN+ L + Sbjct: 559 TSTVTFIVQVNSLPSPPQFVD---QG--TAAYTFTPPDGRTISGSAASNTLTLPVS 609 >C2X9S1.1 C2X9S1_BACCE Cell surface protein Length = 5010 Score = 199 bits (505), Expect = 9e-49, Method: Compositional matrix adjust. Identities = 167/541 (30%), Positives = 260/541 (48%), Gaps = 23/541 (4%) Query: 31 SNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGNAPALT-TLVDALPSGVSFV 89 SNTVNT VV L+++KS D S T+ YT++ +N GN A T TL D +P G +F+ Sbjct: 3385 SNTVNTAVVDASLSVIKSTDSLVQSTDGTITYTVVVQNNGNTTANTVTLTDLVPEGTAFI 3444 Query: 90 ANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTT 149 NSV +GV +PG P GI L ++ P V + FQVIV S+P + N AR Y+F Sbjct: 3445 PNSVTINGVSVPGADPNVGIPLNSITPSEIVTVTFQVIVQSIPSVNPISNTARIDYTFIA 3504 Query: 150 -PEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGIL 208 P + + SN + + L A + P T GD +T+T+ + N G + ++ Sbjct: 3505 DPTAPIISRTITSNPAFTQISDATILSLKAVNAPQTTTGDILTYTITLENTGNIQATNLI 3564 Query: 209 TTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRV---VSVPAL 265 + +P+ F+ S G A+P+ G+ LP L T ISFQ+ + S ++ Sbjct: 3565 FSDTIPQDTTFVENSFTLNGTAILGANPNVGVTLPTLAANATHLISFQILIKDSFSRESI 3624 Query: 266 TAQAVVTYDADGD------TDGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTI 319 T Q+ TY D T+ + SN V +Q+ L+++ + + G + Y + Sbjct: 3625 TNQSNTTYTIQPDPGQSPITETSTSNIVITNFVQAQLTITKTSNPTTVDIGGTILYISEV 3684 Query: 320 RNSGKL-AVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDLL 378 +N G + A++ + +IP+GT FV DSV I+G+ Q GV+P GIP+GTI A S+ + Sbjct: 3685 KNIGNVDAINIVFTDSIPAGTTFVPDSVTINGVLQPGVNPENGIPIGTIPANSSKTILFQ 3744 Query: 379 VSI---PAEADILQMPAIQNQGSVEYTF-TLPDGRNVRERVRSNTVTTLLFSPVISIEMT 434 V P E +I+ NQ S Y + ++P V SN VTT L + I + Sbjct: 3745 VQTNNPPTETEIV------NQSSATYQYVSIPTAPPVNRSANSNIVTTSLQNANIISVKS 3798 Query: 435 GEPPMVEPGGIAEFNIAVTNSGNYPAEVSV-IQIIPQGCTLETGKVTISVHTVPESKYSG 493 + G I + + N G PA +V I IP+G + I+ P + Sbjct: 3799 ADITFASIGQIITYTNTLQNIGTVPANNTVFIDNIPEGTIFIEDSLAINNVIQPGANPEN 3858 Query: 494 IVSLGVMDPGQTAQLSYLVRVHPGYMGSALQGSSTALYLYTIDGRRYSGEARSNSYKLMI 553 V+LG + P +T +S+ V++ +G+ + S Y Y ID + RS S + Sbjct: 3859 GVTLGTIQPNETVTISFQVQLTNIPVGNVVINISDTSYEYQIDPSSQIIQRRSLSNAVNT 3918 Query: 554 E 554 E Sbjct: 3919 E 3919 Score = 185 bits (470), Expect = 9e-45, Method: Compositional matrix adjust. Identities = 148/507 (29%), Positives = 238/507 (46%), Gaps = 23/507 (4%) Query: 42 VLTLVKSADHTSASLGETLVYTLIARNEGNAPALT-TLVDALPSGVSFVANSVLRDGVPL 100 +L+ VK+A+ A++G+T+ YT+ +N GN A D +P+G +FV NS +G + Sbjct: 3132 ILSAVKTANTAFANIGDTITYTVSIQNNGNTNATNVNFSDPVPTGTTFVENSFAVNGSTI 3191 Query: 101 PGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTT-PEGRHVEGEV 159 PG +P +G+ +G V+ + + + FQVIV S PPS + N A Y+F P V G + Sbjct: 3192 PGANPNNGVNIGTVSAGSSLTVTFQVIVTSTPPSNPITNVASIQYAFIVDPASPPVTGTI 3251 Query: 160 FSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGILTTLPVPEGAIF 219 SN + + ++ +L ++ +GD +T+T + N G + +L VPEGA+F Sbjct: 3252 NSNSASTQINNATVTTVLQANRSIVSIGDVITYTATLTNTGNFPANSVLLINGVPEGALF 3311 Query: 220 LPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVP---ALTAQAVVTYDAD 276 +P SV GI PDA P GIP+ + PG +A I+FQ S+P A+ QA+ +Y Sbjct: 3312 VPNSVTLNGISLPDASPTLGIPVGIIAPGDSATITFQFLASSIPPQGAIINQALTSYTYI 3371 Query: 277 GD------TDGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTIRNSGKLAVDAM 330 D T + SNTV AV+ + LSV D + + Y ++N+G + + Sbjct: 3372 VDPSQPPVTATSSSNTVNTAVVDASLSVIKSTDSLVQSTDGTITYTVVVQNNGNTTANTV 3431 Query: 331 -LAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDLLV---SIPAEAD 386 L +P GT F+ +SV I+G+ G P GIPL +I V V SIP+ Sbjct: 3432 TLTDLVPEGTAFIPNSVTINGVSVPGADPNVGIPLNSITPSEIVTVTFQVIVQSIPS--- 3488 Query: 387 ILQMPAIQNQGSVEYTFTL-PDGRNVRERVRSNTVTTLLFSPVISIEMTGEPPMVEPGGI 445 + I N ++YTF P + + SN T + I P G I Sbjct: 3489 ---VNPISNTARIDYTFIADPTAPIISRTITSNPAFTQISDATILSLKAVNAPQTTTGDI 3545 Query: 446 AEFNIAVTNSGNYPAEVSVI-QIIPQGCTLETGKVTISVHTVPESKYSGIVSLGVMDPGQ 504 + I + N+GN A + IPQ T T++ + + + V+L + Sbjct: 3546 LTYTITLENTGNIQATNLIFSDTIPQDTTFVENSFTLNGTAILGANPNVGVTLPTLAANA 3605 Query: 505 TAQLSYLVRVHPGYMGSALQGSSTALY 531 T +S+ + + + ++ S Y Sbjct: 3606 THLISFQILIKDSFSRESITNQSNTTY 3632 Score = 178 bits (452), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 163/531 (30%), Positives = 258/531 (48%), Gaps = 41/531 (7%) Query: 31 SNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGNAPALTTLV-DALPSGVSFV 89 SN VNT V ++ +KSA+ + +G+ + YT+ N G P TL+ DA+ SG +FV Sbjct: 3913 SNAVNTEVRTANVSAIKSANRSITRIGQIITYTVAVTNAGTIPITNTLLLDAIASGTTFV 3972 Query: 90 ANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFT- 148 NS+L DGVP +P +GI L + P + + FQV VVS+PP + N A Y + Sbjct: 3973 PNSILVDGVPRLNENPITGINLDIILPNNTIIVTFQVSVVSIPPQNNINNIAVIHYEYRP 4032 Query: 149 TPEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGIL 208 P + SN + + L +++T + + + +T+ ++N G+ + I Sbjct: 4033 DPSTPPISETTSSNATNIQFIDAILIATKSTNTVLANIDETIEYTVFIQNNGSATTNSIF 4092 Query: 209 TTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVPALT-- 266 T + +G +F+PGSV+ P ADP+ G +P + G+ A I+FQV V ++PA+ Sbjct: 4093 FTDTIADGTVFIPGSVVVNNTVLPAADPNIGFSIPNVAAGQMATITFQVSVTNLPAVNPT 4152 Query: 267 -AQAVVTYDADGDTD------GTKSNTVTVAVIQSGLSVSLK-VDKYSAAPGDRLGYRFT 318 A V YD + D T SNT V + + + VSLK VD S GD L Y T Sbjct: 4153 PNTANVVYDFIFNPDFAPIQKSTTSNTTFVQINDADI-VSLKTVDLTSVTIGDILTYTTT 4211 Query: 319 IRNSGKL-AVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDL 377 + N+G A + IP+GT F+ SV ++ IPQ +P GI +GTI Sbjct: 4212 LTNTGNTDATAVVFTDNIPNGTTFIDGSVLVNNIPQLNANPSAGILVGTIAPN------- 4264 Query: 378 LVSIPA--EADILQMPA---IQNQGSVEYTFTLPDGRNVRERVRSNTVTTLLFSPVISIE 432 +SIP ++ +PA +QNQ + YT NV E++ ++ +T F+ VIS Sbjct: 4265 -ISIPVTFSVTVVALPASGHVQNQSTSRYTI------NVEEQISTSNIT---FTEVISAN 4314 Query: 433 M--TGEPPM--VEPGGIAEFNIAVTNSGNYPAE-VSVIQIIPQGCTLETGKVTISVHTVP 487 + T P+ + I + I++TN+GN E + V IIP + V ++ + P Sbjct: 4315 VIATKTTPIQYADLQTIIPYTISITNNGNIQVENIIVTDIIPANTSFIENSVIVNGNARP 4374 Query: 488 ESKYSGIVSLGVMDPGQTAQLSYLVRVHPGYMGSALQGSSTALYLYTIDGR 538 + + + P TA + + VRV + + +ST Y YT+ R Sbjct: 4375 NDNPLNGIQIDNIPPNTTATILFQVRVTSIPQTNPISNTSTIEYEYTVPNR 4425 Score = 166 bits (421), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 156/540 (28%), Positives = 253/540 (46%), Gaps = 40/540 (7%) Query: 41 PVLTLVKSADHTSASLGETLVYTLIARNEGNAPALTTL-VDALPSGVSFVANSVLRDGVP 99 P + KS + + A++G+ L YT+ N G PA + +D+LPSG SF+ +V D VP Sbjct: 350 PNIQATKSVNKSVAAIGDILTYTVTIPNTGLLPANNAIFIDSLPSGTSFIPGTVTVDNVP 409 Query: 100 LPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTTPEGRHVEGEV 159 +P +GI LG + + FQ VVSLP + N A + +T G G Sbjct: 410 QTNANPAAGISLGTINNGASRTVTFQATVVSLPSQNPISNTANITFQYTPIAG----GTT 465 Query: 160 FSNQITVSLLAYKLSILLASSTPT-----TFVGDAVTFTLRVRNEGTRLMSGILTTLPVP 214 F+ T + ++++ + T + T +G+ +T+++ + N G + ++ T P+P Sbjct: 466 FNGLATSNSAGTQINLADINGTKSVNKLFTDIGETLTYSIALANIGNIAATNVIYTDPIP 525 Query: 215 EGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVPA---LTAQAVV 271 G F+ GSV G+ A+P GI + + T ISFQV V S+P + Sbjct: 526 SGTTFISGSVTVNGVTQAGANPANGISIGSIAANSTTTISFQVLVPSIPQTNPILNSGTT 585 Query: 272 TYD--------ADGDTDGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTIRNSG 323 TY A TD K+N V+ V + ++++ VDK A GD L Y + +G Sbjct: 586 TYQYIPVPNQPAVSGTD--KTNIVSTQVNNATVTMTKAVDKNFADIGDTLTYTVSFTATG 643 Query: 324 KL-AVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDLLV--- 379 A + + IP+GT FV +S+ IDG Q G +P G+ +G+I +G+ V V Sbjct: 644 NTNANNVIFIDVIPTGTTFVLNSLTIDGTTQVGANPANGVNIGSIPSGTTKNVAFQVVVN 703 Query: 380 SIPAEADILQMPAIQNQGSVEYTFTL-PDGRNVRERVRSNTVTTLLFSPVISIEMTGEPP 438 +IPA + N S Y +T+ P V + + SN V+T + + +++ + Sbjct: 704 TIPASN------VVSNGSSASYQYTVNPSQSPVTKNIFSNLVSTQINNANVTLTKSTNKQ 757 Query: 439 MVEPGGIAEFNIAVTNSGNYPA-EVSVIQIIPQGCTLETGKVTISVHTVPESKYSGI-VS 496 G + I +TNSGN A V + +P G L G VT+ + V ++ S + + Sbjct: 758 FATIGETISYTILITNSGNMAANNVQLTDPLPNGTILTPGTVTL--NGVLQNVDSLVALP 815 Query: 497 LGVMDPGQTAQLSYLVRVHPGYMGSALQGSSTALYLYTIDGRR--YSGEARSNSYKLMIE 554 +G + G T LS+ V V + + ++ A YLYT++ S A SNS I Sbjct: 816 IGTIPGGATFTLSFQVTVINITTQNPIINNAFASYLYTVNPNLPPTSKTANSNSVTSTIR 875 Score = 162 bits (409), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 150/497 (30%), Positives = 236/497 (47%), Gaps = 23/497 (4%) Query: 31 SNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGNAPALTTL-VDALPSGVSFV 89 SNTV T + + KSAD A++ + + YT N GN A + D +P+G SF+ Sbjct: 1394 SNTVQTTINNASIAATKSADKQFANVNDIITYTTTLTNNGNTLASNVIFTDVIPNGTSFI 1453 Query: 90 ANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTT 149 ANSV +G LP V+P SGI + + P I+FQV V S+P L N++ Y + Sbjct: 1454 ANSVTVNGNTLPNVNPASGIAIDPINPNANTLISFQVQVNSIPNPNPLPNQSNTTYQYVV 1513 Query: 150 -PEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGIL 208 P SN IT + + + +TPT +GD VT+T+ V N G S + Sbjct: 1514 DPNLPPASANTLSNVITTQINNATIVATKSVNTPTAAIGDIVTYTIAVTNTGNTPASATV 1573 Query: 209 TTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVP---AL 265 T + GA F+ SV + P DP GI L + PG T I+FQ +++++P L Sbjct: 1574 LTDGLGAGASFIQNSVTINNVPQPGLDPSLGIHLADISPGDTVFITFQAQILAIPPSGTL 1633 Query: 266 TAQAVVTYDADGD------TDGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTI 319 T A+V Y+ + + T +NT +I + LS++ V+ A GD L + TI Sbjct: 1634 TNNALVNYEYTVNPNQSPAVNSTITNTTVTPIIDATLSINKTVNSTFATIGDTLTFTSTI 1693 Query: 320 RNSGK-LAVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDLL 378 NSG A + + IP+GT F+ +S ++G +P GI +G + + ++A + Sbjct: 1694 TNSGNTTANNVIFTDVIPNGTTFIPNSFTVNGTTITNANPQNGINIGNLNSNASATLSFQ 1753 Query: 379 VSIPAEADILQMPAIQNQGSVEYTFTLP-DGRNVRERVRSNTVTTLLFSPVISIEMTGEP 437 V+I + +P N+ S++Y+F + + V V+SN T + + + T Sbjct: 1754 VNITTLPNPNPIP---NKSSLQYSFIVDINEPPVSRTVQSNKTFTQVNTASVIATKTASS 1810 Query: 438 PMVEPGGIAEFNIAVTNSGNYPAEVSV-IQIIPQGCTLETGKVTISVHTVPESKY---SG 493 G + +TNSGN A V I I+P + V I +T+P+ + SG Sbjct: 1811 AFAAVGDTITYTTILTNSGNTSANTPVFIDILPPELSFVPDSVQI--NTIPQLGFRPDSG 1868 Query: 494 IVSLGVMDPGQTAQLSY 510 I SL + G T +S+ Sbjct: 1869 I-SLDSIPVGGTTTISF 1884 Score = 161 bits (407), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 156/519 (30%), Positives = 244/519 (47%), Gaps = 25/519 (4%) Query: 11 VSNQSMVLYSSAAGADVITYSNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEG 70 V NQS Y+ + I+ SN T V+ + K+ A L + YT+ N G Sbjct: 4284 VQNQSTSRYTINV-EEQISTSNITFTEVISANVIATKTTPIQYADLQTIIPYTISITNNG 4342 Query: 71 NAPALTTLV-DALPSGVSFVANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVV 129 N +V D +P+ SF+ NSV+ +G P +P +GI + + P T I FQV V Sbjct: 4343 NIQVENIIVTDIIPANTSFIENSVIVNGNARPNDNPLNGIQIDNIPPNTTATILFQVRVT 4402 Query: 130 SLPPSLELGNRARAVYSFTTPEGRHVEGEVFSN----QITVSLLAYKLSILLASSTPTTF 185 S+P + + N + Y +T P + + S+ +I + L ++ LA +T Sbjct: 4403 SIPQTNPISNTSTIEYEYTVPNRPPITETIISSAALTEINHANLNSNKAVDLAFAT---- 4458 Query: 186 VGDAVTFTLRVRNEGTRLMSGILTTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPL 245 VGD +T+T+ + G ++ ++ +P+G F+ SVI G P +P GIP+ + Sbjct: 4459 VGDTLTYTITLNQTGNVAVNDVIIQDIIPQGTTFIENSVIVNGETLPGVNPVSGIPIGTI 4518 Query: 246 DPGKTADISFQVRVVSVPA---LTAQAVVTYD-----ADGDTDGTKSNTVTVAVIQSGLS 297 G A +SFQV V S+P L A+ T++ + T + +Q+ Sbjct: 4519 TIGGDAIVSFQVTVTSIPTPNELNNNAITTFNYIVNPNNVPVTNTTTTNTVKTTVQNDNV 4578 Query: 298 VSLK-VDKYSAAPGDRLGYRFTIRNSGKLAVDAMLA-GAIPSGTLFVWDSVHIDGIPQRG 355 ++ K D +A PG L Y TI NSG + ++ +LA A+P T FV SV I+GI Q Sbjct: 4579 IAFKSADVTNALPGQTLTYTITITNSGNVTIEDLLAIDAVPIDTTFVAGSVTINGINQPN 4638 Query: 356 VHPGEGIPLGTIRAGSAAVVDLLVSIPAEADILQMPAIQNQGSVEYTFTL-PDGRNVRER 414 +P GI LG + ++ V+I + LQ I N SV YT + P + Sbjct: 4639 ENPENGITLGNLAPNEFVIITFQVTI--SSSTLQS-TINNDASVSYTVIIDPTKPPITIT 4695 Query: 415 VRSNTVTTLLFSPVISIEMTGEPPMVEPGGIAEFNIAVTNSGNYPA-EVSVIQIIPQGCT 473 ++NTVTT + P++ IE T + +V G I F +AV N P SVI IP G T Sbjct: 4696 KQTNTVTTTVIDPMVRIEKTADKSIVVIGDIITFTLAVFNHSPIPTISTSVIDTIPAGTT 4755 Query: 474 LETGKVTISVHTVPESKYSGIVSLGVMDPGQTAQLSYLV 512 VTI+ VP + +++G + G A +++ V Sbjct: 4756 FIENSVTINGTPVPNVRPDTGINIGSLSAGTVATITFQV 4794 Score = 156 bits (395), Expect = 5e-36, Method: Compositional matrix adjust. Identities = 147/536 (27%), Positives = 242/536 (45%), Gaps = 30/536 (5%) Query: 18 LYSSAAGADVITYSNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGNAPALT- 76 L +AA V T NT N +V LT AD +G+ ++Y I N GN PA Sbjct: 1256 LVRNAASNIVTTQINTAN--IVATKLTSTNFAD-----VGDVILYATILTNNGNIPAANV 1308 Query: 77 TLVDALPSGVSFVANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLE 136 T D +P+G F+ N+V + VP+ +P +GI +G + + +AFQV V ++P Sbjct: 1309 TFTDIIPAGTLFIPNTVTINNVPVANANPATGISIGTIGANSSRTVAFQVFVPTIPAVNP 1368 Query: 137 LGNRARAVYSFT-TPEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLR 195 + N++ + +T P V V SN + ++ ++ ++ V D +T+T Sbjct: 1369 ITNQSGTTFQYTYDPSKPAVMQMVASNTVQTTINNASIAATKSADKQFANVNDIITYTTT 1428 Query: 196 VRNEGTRLMSGILTTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISF 255 + N G L S ++ T +P G F+ SV G P+ +P GI + P++P ISF Sbjct: 1429 LTNNGNTLASNVIFTDVIPNGTSFIANSVTVNGNTLPNVNPASGIAIDPINPNANTLISF 1488 Query: 256 QVRVVSVPA---LTAQAVVTYDADGDTD------GTKSNTVTVAVIQSGLSVSLKVDKYS 306 QV+V S+P L Q+ TY D + T SN +T + + + + V+ + Sbjct: 1489 QVQVNSIPNPNPLPNQSNTTYQYVVDPNLPPASANTLSNVITTQINNATIVATKSVNTPT 1548 Query: 307 AAPGDRLGYRFTIRNSGKLAVDA-MLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLG 365 AA GD + Y + N+G A +L + +G F+ +SV I+ +PQ G+ P GI L Sbjct: 1549 AAIGDIVTYTIAVTNTGNTPASATVLTDGLGAGASFIQNSVTINNVPQPGLDPSLGIHLA 1608 Query: 366 TIRAGSAAVVDLLVSIPAEADILQMP---AIQNQGSVEYTFTL-PDGRNVRERVRSNTVT 421 I G + +A IL +P + N V Y +T+ P+ +NT Sbjct: 1609 DISPGDTVFITF------QAQILAIPPSGTLTNNALVNYEYTVNPNQSPAVNSTITNTTV 1662 Query: 422 TLLFSPVISIEMTGEPPMVEPGGIAEFNIAVTNSGNYPA-EVSVIQIIPQGCTLETGKVT 480 T + +SI T G F +TNSGN A V +IP G T T Sbjct: 1663 TPIIDATLSINKTVNSTFATIGDTLTFTSTITNSGNTTANNVIFTDVIPNGTTFIPNSFT 1722 Query: 481 ISVHTVPESKYSGIVSLGVMDPGQTAQLSYLVRVHPGYMGSALQGSSTALYLYTID 536 ++ T+ + +++G ++ +A LS+ V + + + S+ Y + +D Sbjct: 1723 VNGTTITNANPQNGINIGNLNSNASATLSFQVNITTLPNPNPIPNKSSLQYSFIVD 1778 Score = 151 bits (382), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 145/504 (28%), Positives = 239/504 (47%), Gaps = 25/504 (4%) Query: 31 SNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGNAPALTTLV-DALPSGVSFV 89 SN V T + +L +K D T A++G+T+ YT N GN PA + D LPS FV Sbjct: 2987 SNNVTTKIESAILNTIKIGDKTFATIGDTITYTTTITNTGNIPANNAIFSDPLPSWTQFV 3046 Query: 90 ANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSL--ELGNRARAVYSF 147 A SV+ DG PLP S +G+ + ++P V I FQV +VS P + EL N + + Sbjct: 3047 AGSVIVDGTPLPSASIINGVGINTISPNQTVTIIFQVQIVSNPTTFTPELQNLGFVNFQY 3106 Query: 148 TTPEGRHVE-GEVFSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSG 206 + G V +N S+ LS + ++T +GD +T+T+ ++N G + Sbjct: 3107 NVGNALLAQPGNVETNVFVTSINTAILSAVKTANTAFANIGDTITYTVSIQNNGNTNATN 3166 Query: 207 ILTTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVP--- 263 + + PVP G F+ S G P A+P+ G+ + + G + ++FQV V S P Sbjct: 3167 VNFSDPVPTGTTFVENSFAVNGSTIPGANPNNGVNIGTVSAGSSLTVTFQVIVTSTPPSN 3226 Query: 264 ALTAQAVVTYDADGD------TDGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRF 317 +T A + Y D T SN+ + + + ++ L+ ++ + GD + Y Sbjct: 3227 PITNVASIQYAFIVDPASPPVTGTINSNSASTQINNATVTTVLQANRSIVSIGDVITYTA 3286 Query: 318 TIRNSGKLAVDA-MLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVD 376 T+ N+G ++ +L +P G LFV +SV ++GI P GIP+G I G +A + Sbjct: 3287 TLTNTGNFPANSVLLINGVPEGALFVPNSVTLNGISLPDASPTLGIPVGIIAPGDSATIT 3346 Query: 377 ---LLVSIPAEADILQMPAIQNQGSVEYTFTL-PDGRNVRERVRSNTVTTLLFSPVISIE 432 L SIP + AI NQ YT+ + P V SNTV T + +S+ Sbjct: 3347 FQFLASSIPPQG------AIINQALTSYTYIVDPSQPPVTATSSSNTVNTAVVDASLSVI 3400 Query: 433 MTGEPPMVEPGGIAEFNIAVTNSGNYPAE-VSVIQIIPQGCTLETGKVTISVHTVPESKY 491 + + + G + + V N+GN A V++ ++P+G VTI+ +VP + Sbjct: 3401 KSTDSLVQSTDGTITYTVVVQNNGNTTANTVTLTDLVPEGTAFIPNSVTINGVSVPGADP 3460 Query: 492 SGIVSLGVMDPGQTAQLSYLVRVH 515 + + L + P + +++ V V Sbjct: 3461 NVGIPLNSITPSEIVTVTFQVIVQ 3484 Score = 151 bits (382), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 114/385 (29%), Positives = 194/385 (50%), Gaps = 17/385 (4%) Query: 31 SNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGNAPALTTL-VDALPSGVSFV 89 +N V+T V +T+ K+ D A +G+TL YT+ GN A + +D +P+G +FV Sbjct: 604 TNIVSTQVNNATVTMTKAVDKNFADIGDTLTYTVSFTATGNTNANNVIFIDVIPTGTTFV 663 Query: 90 ANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFT- 148 NS+ DG G +P +G+ +G++ T +AFQV+V ++P S + N + A Y +T Sbjct: 664 LNSLTIDGTTQVGANPANGVNIGSIPSGTTKNVAFQVVVNTIPASNVVSNGSSASYQYTV 723 Query: 149 TPEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGIL 208 P V +FSN ++ + +++ +++ +G+ +++T+ + N G + + Sbjct: 724 NPSQSPVTKNIFSNLVSTQINNANVTLTKSTNKQFATIGETISYTILITNSGNMAANNVQ 783 Query: 209 TTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSV----PA 264 T P+P G I PG+V G+ + D +P+ + G T +SFQV V+++ P Sbjct: 784 LTDPLPNGTILTPGTVTLNGVLQ-NVDSLVALPIGTIPGGATFTLSFQVTVINITTQNPI 842 Query: 265 L-TAQAVVTYDADGD----TDGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTI 319 + A A Y + + + SN+VT + + L + VDK A GD L Y F + Sbjct: 843 INNAFASYLYTVNPNLPPTSKTANSNSVTSTIRLANLHANKSVDKTFAEVGDVLTYTFAL 902 Query: 320 RNSGKLAV-DAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDLL 378 N G +A + +L+ +I +GT FV +SV ++G+ Q GV P I +G+I A + Sbjct: 903 TNDGNVAANNVLLSDSIANGTAFVPNSVIVNGVTQPGVTP-TSINIGSINANTTITASFQ 961 Query: 379 VSIPAEADILQMPAIQNQGSVEYTF 403 V I I I N S+ Y F Sbjct: 962 VVI---TSIPNPNPISNSASISYNF 983 Score = 147 bits (372), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 146/540 (27%), Positives = 248/540 (45%), Gaps = 28/540 (5%) Query: 17 VLYS-----SAAGADVITYSNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGN 71 +LYS ++A A T +N PV+ ++T+VKS D T +LG+T+ YT N GN Sbjct: 2312 ILYSYTVDPNSAPATTSTSTNIATNPVLDAMITMVKSVDQTLVTLGDTITYTTNLTNNGN 2371 Query: 72 APALTT-LVDALPSGVSFVANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVS 130 A D +P+G +F+ +SV +G+ G++P +GI +G++AP + + IAFQV S Sbjct: 2372 TNATNITFTDLIPNGTTFITDSVTINGLTQIGLNPNTGITIGSIAPNSSISIAFQVTATS 2431 Query: 131 LPPSLELGNRARAVYSFTT-PEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTFVGDA 189 P + N A A Y+F P V V SN + ++ + L + +GD Sbjct: 2432 TPVQNPIANSATASYTFIADPNAPIVSRNVTSNTVFTTINTANILSLKQVDKSFSRIGDT 2491 Query: 190 VTFTLRVRNEGTRLMSGILTTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGK 249 +T+T+ + N G ++ T VP F+ + G+ ADP G+ + + G Sbjct: 2492 LTYTVVLTNNGNSSAQNVIFTDTVPSVTTFIANTFSINGVPQSGADPSNGVNIGTITAGT 2551 Query: 250 TADISFQVRVVSVPALTAQAVVTYDADG-------DTDGTKSNTVTVAVIQSGLSVSLKV 302 T +SFQV V S+P TA +V + + + + + SN V+ + ++ LS++ Sbjct: 2552 TVTVSFQVTVTSLP--TANPIVNFSSTSYQLVSPPEAETSISNPVSTQIKEAILSMTKNE 2609 Query: 303 DKYSAAPGDRLGYRFTIRNSGKL-AVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEG 361 A G Y +I N G A + + A+PSG FV +++ +DG+ Q P G Sbjct: 2610 SVSFADIGQTAFYTTSITNVGNTDATNIVFTDALPSGLTFVPNTLTVDGVLQPNADPNTG 2669 Query: 362 IPLGTIRAGSAAVVDLLVSIPAEADILQMPAIQ---NQGSVEYTFTL-PDGRNVRERVRS 417 + L T+ + SI + + +P N S Y FT+ P V S Sbjct: 2670 VLLATLPPNE------IYSIVFQVTVNNIPPSNPAPNTASTTYEFTVDPVNPPVSSAATS 2723 Query: 418 NTVTTLLFSPVISIEMTGEPPMVEPGGIAEFNIAVTNSGNYPA-EVSVIQIIPQGCTLET 476 NT + + I T + G F + + N+GN A +V++I I+ + Sbjct: 2724 NTTLLQINNATIISTKTANLTFADVGNTITFTLNLPNTGNVTATDVTIIDILDSNLSFVP 2783 Query: 477 GKVTISVHTVPESKYSGIVSLGVMDPGQTAQLSYLVRVHPGYMGSALQGSSTALYLYTID 536 T + T+P + S V++G ++ G TA +++ V + + S++ Y Y +D Sbjct: 2784 NSFTANGQTIPNADLSTGVNIGSINGGNTAIVTFQATVITLPTLNPISNSASTTYHYVVD 2843 Score = 147 bits (370), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 142/510 (27%), Positives = 236/510 (46%), Gaps = 28/510 (5%) Query: 46 VKSADHTSASLGETLVYTLIARNEGNAPALT-TLVDALPSGVSFVANSVLRDGVPLPGVS 104 +K+ D TS ++G+ L YT N GN A D +P+G +F+ SVL + +P + Sbjct: 4192 LKTVDLTSVTIGDILTYTTTLTNTGNTDATAVVFTDNIPNGTTFIDGSVLVNNIPQLNAN 4251 Query: 105 PFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTTPEGRHVEGEVFSNQI 164 P +GIL+G +AP + + F V VV+LP S + N++ + Y+ E F+ I Sbjct: 4252 PSAGILVGTIAPNISIPVTFSVTVVALPASGHVQNQSTSRYTINVEEQISTSNITFTEVI 4311 Query: 165 TVSLLAYKLSILLASSTPTTF--VGDAVTFTLRVRNEGTRLMSGILTTLPVPEGAIFLPG 222 + +++A K +TP + + + +T+ + N G + I+ T +P F+ Sbjct: 4312 SANVIATK-------TTPIQYADLQTIIPYTISITNNGNIQVENIIVTDIIPANTSFIEN 4364 Query: 223 SVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVPA---LTAQAVVTYDADGD- 278 SVI G P+ +P GI + + P TA I FQVRV S+P ++ + + Y+ Sbjct: 4365 SVIVNGNARPNDNPLNGIQIDNIPPNTTATILFQVRVTSIPQTNPISNTSTIEYEYTVPN 4424 Query: 279 ----TDGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTIRNSGKLAV-DAMLAG 333 T+ S+ + + L+ + VD A GD L Y T+ +G +AV D ++ Sbjct: 4425 RPPITETIISSAALTEINHANLNSNKAVDLAFATVGDTLTYTITLNQTGNVAVNDVIIQD 4484 Query: 334 AIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDLLV---SIPAEADILQM 390 IP GT F+ +SV ++G GV+P GIP+GTI G A+V V SIP + L Sbjct: 4485 IIPQGTTFIENSVIVNGETLPGVNPVSGIPIGTITIGGDAIVSFQVTVTSIPTPNE-LNN 4543 Query: 391 PAIQNQGSVEYTFTLPDGRNVRERVRSNTVTTLLFSPVISIEMTGEPPMVEPGGIAEFNI 450 AI + Y + + TT+ VI+ + + + PG + I Sbjct: 4544 NAIT---TFNYIVNPNNVPVTNTTTTNTVKTTVQNDNVIAFK-SADVTNALPGQTLTYTI 4599 Query: 451 AVTNSGNYPAE-VSVIQIIPQGCTLETGKVTISVHTVPESKYSGIVSLGVMDPGQTAQLS 509 +TNSGN E + I +P T G VTI+ P ++LG + P + ++ Sbjct: 4600 TITNSGNVTIEDLLAIDAVPIDTTFVAGSVTINGINQPNENPENGITLGNLAPNEFVIIT 4659 Query: 510 YLVRVHPGYMGSALQGSSTALYLYTIDGRR 539 + V + + S + ++ Y ID + Sbjct: 4660 FQVTISSSTLQSTINNDASVSYTVIIDPTK 4689 Score = 143 bits (361), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 121/416 (29%), Positives = 207/416 (49%), Gaps = 24/416 (5%) Query: 1 MIRDSRLQPVVSNQSMVLYS--SAAGADVITYSNTVN---TPVVGPVLTLVKSADHTSAS 55 +I+DS + ++NQS Y+ G IT ++T N T V LT+ K+++ T+ Sbjct: 3614 LIKDSFSRESITNQSNTTYTIQPDPGQSPITETSTSNIVITNFVQAQLTITKTSNPTTVD 3673 Query: 56 LGETLVYTLIARNEGNAPALT-TLVDALPSGVSFVANSVLRDGVPLPGVSPFSGILLGAV 114 +G T++Y +N GN A+ D++P+G +FV +SV +GV PGV+P +GI +G + Sbjct: 3674 IGGTILYISEVKNIGNVDAINIVFTDSIPAGTTFVPDSVTINGVLQPGVNPENGIPIGTI 3733 Query: 115 APQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTT-PEGRHVEGEVFSNQITVSLLAYKL 173 + I FQV + P E+ N++ A Y + + P V SN +T SL Sbjct: 3734 PANSSKTILFQVQTNNPPTETEIVNQSSATYQYVSIPTAPPVNRSANSNIVTTSL--QNA 3791 Query: 174 SILLASSTPTTF--VGDAVTFTLRVRNEGTRLMSGILTTLPVPEGAIFLPGSVISGGIYS 231 +I+ S TF +G +T+T ++N GT + + +PEG IF+ S+ + Sbjct: 3792 NIISVKSADITFASIGQIITYTNTLQNIGTVPANNTVFIDNIPEGTIFIEDSLAINNVIQ 3851 Query: 232 PDADPDKGIPLPPLDPGKTADISFQVRVVSVP---ALTAQAVVTYDADGDTDG------T 282 P A+P+ G+ L + P +T ISFQV++ ++P + + +Y+ D + Sbjct: 3852 PGANPENGVTLGTIQPNETVTISFQVQLTNIPVGNVVINISDTSYEYQIDPSSQIIQRRS 3911 Query: 283 KSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTIRNSGKLAV-DAMLAGAIPSGTLF 341 SN V V + +S ++ G + Y + N+G + + + +L AI SGT F Sbjct: 3912 LSNAVNTEVRTANVSAIKSANRSITRIGQIITYTVAVTNAGTIPITNTLLLDAIASGTTF 3971 Query: 342 VWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDL---LVSIPAEADILQMPAIQ 394 V +S+ +DG+P+ +P GI L I + +V +VSIP + +I + I Sbjct: 3972 VPNSILVDGVPRLNENPITGINLDIILPNNTIIVTFQVSVVSIPPQNNINNIAVIH 4027 Score = 138 bits (348), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 123/487 (25%), Positives = 230/487 (47%), Gaps = 23/487 (4%) Query: 42 VLTLVKSADHTSASLGETLVYTLIARNEGNAPALTTL-VDALPSGVSFVANSVLRDGVPL 100 +LT K+++ ++ +G+ + YT+ N GN A + D +P G SF NS +G + Sbjct: 2866 ILTAQKNSNVSTVDIGQDITYTVTITNSGNVSATNVIFTDLIPDGTSFEPNSFTLNGTSI 2925 Query: 101 PGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYS-FTTPEGRHVEGEV 159 P +G+ +G +AP V +AF +I +PP + N+A + P V + Sbjct: 2926 PNADIITGVPIGDIAPNESVIVAFHIIANEIPPINPITNQASVSFQHIVNPANLPVSKNI 2985 Query: 160 FSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGILTTLPVPEGAIF 219 SN +T + + L+ + +GD +T+T + N G + + + P+P F Sbjct: 2986 ISNNVTTKIESAILNTIKIGDKTFATIGDTITYTTTITNTGNIPANNAIFSDPLPSWTQF 3045 Query: 220 LPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVS-----VPALTAQAVVTYD 274 + GSVI G P A G+ + + P +T I FQV++VS P L V + Sbjct: 3046 VAGSVIVDGTPLPSASIINGVGINTISPNQTVTIIFQVQIVSNPTTFTPELQNLGFVNFQ 3105 Query: 275 AD------GDTDGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTIRNSGKL-AV 327 + ++N ++ + LS + A GD + Y +I+N+G A Sbjct: 3106 YNVGNALLAQPGNVETNVFVTSINTAILSAVKTANTAFANIGDTITYTVSIQNNGNTNAT 3165 Query: 328 DAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDLLVSIPAEADI 387 + + +P+GT FV +S ++G G +P G+ +GT+ AGS+ V V + + Sbjct: 3166 NVNFSDPVPTGTTFVENSFAVNGSTIPGANPNNGVNIGTVSAGSSLTVTFQVIVTSTP-- 3223 Query: 388 LQMPA--IQNQGSVEYTFTL-PDGRNVRERVRSNTVTTLLFSPVISIEMTGEPPMVEPGG 444 P+ I N S++Y F + P V + SN+ +T + + ++ + +V G Sbjct: 3224 ---PSNPITNVASIQYAFIVDPASPPVTGTINSNSASTQINNATVTTVLQANRSIVSIGD 3280 Query: 445 IAEFNIAVTNSGNYPAE-VSVIQIIPQGCTLETGKVTISVHTVPESKYSGIVSLGVMDPG 503 + + +TN+GN+PA V +I +P+G VT++ ++P++ + + +G++ PG Sbjct: 3281 VITYTATLTNTGNFPANSVLLINGVPEGALFVPNSVTLNGISLPDASPTLGIPVGIIAPG 3340 Query: 504 QTAQLSY 510 +A +++ Sbjct: 3341 DSATITF 3347 Score = 137 bits (345), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 134/505 (26%), Positives = 227/505 (44%), Gaps = 19/505 (3%) Query: 47 KSADHTSASLGETLVYTLIARNEGNAPALT-TLVDALPSGVSFVANSVLRDGVPLPGVSP 105 K+ D A++G+ L YT+ N G+ A + T VD P G +F+ N+ L +GV P Sbjct: 1014 KTVDRAFATVGDILTYTVTLTNAGSVSADSPTFVDTNPDGTTFIPNTFLINGVLQNNADP 1073 Query: 106 FSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTTPEGR--HVEGEVFSNQ 163 G+ L ++A + +++QV V SLP N + YSF G VE V SN Sbjct: 1074 NIGVPLPSIAANGSLTVSYQVTVTSLPTQNPTINSSSTQYSFILNPGDPPTVETSV-SNT 1132 Query: 164 ITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGILTTLPVPEGAIFLPGS 223 ++ + + I+ VG +T+T+ + N G + + ++ T +P G +P S Sbjct: 1133 VSTQINLANVVIVKEVDLTIADVGQPITYTIYLANLGNTIANNVIVTDIIPNGTTIVPNS 1192 Query: 224 VISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVPA---LTAQAVVTYDADGDTD 280 + GG ADP G+ + + G I FQ+ +P+ + A + Y D + Sbjct: 1193 IFIGGALQLGADPSTGLQVGSIPSGGFTTIVFQISANGLPSPNPIQNSASLQYSFIADPN 1252 Query: 281 ------GTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTIRNSGKL-AVDAMLAG 333 SN VT + + + + A GD + Y + N+G + A + Sbjct: 1253 LPALVRNAASNIVTTQINTANIVATKLTSTNFADVGDVILYATILTNNGNIPAANVTFTD 1312 Query: 334 AIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDLLVSIPAEADILQMPAI 393 IP+GTLF+ ++V I+ +P +P GI +GTI A S+ V V +P I + I Sbjct: 1313 IIPAGTLFIPNTVTINNVPVANANPATGISIGTIGANSSRTVAFQVFVPT---IPAVNPI 1369 Query: 394 QNQGSVEYTFTL-PDGRNVRERVRSNTVTTLLFSPVISIEMTGEPPMVEPGGIAEFNIAV 452 NQ + +T P V + V SNTV T + + I+ + + I + + Sbjct: 1370 TNQSGTTFQYTYDPSKPAVMQMVASNTVQTTINNASIAATKSADKQFANVNDIITYTTTL 1429 Query: 453 TNSGNYPA-EVSVIQIIPQGCTLETGKVTISVHTVPESKYSGIVSLGVMDPGQTAQLSYL 511 TN+GN A V +IP G + VT++ +T+P + +++ ++P +S+ Sbjct: 1430 TNNGNTLASNVIFTDVIPNGTSFIANSVTVNGNTLPNVNPASGIAIDPINPNANTLISFQ 1489 Query: 512 VRVHPGYMGSALQGSSTALYLYTID 536 V+V+ + L S Y Y +D Sbjct: 1490 VQVNSIPNPNPLPNQSNTTYQYVVD 1514 Score = 137 bits (344), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 132/500 (26%), Positives = 231/500 (46%), Gaps = 29/500 (5%) Query: 31 SNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGNAPALTTL-VDALPSGVSFV 89 SNTV T + + +K D + + +G+TL YT++ N GN+ A + D +PS +F+ Sbjct: 2463 SNTVFTTINTANILSLKQVDKSFSRIGDTLTYTVVLTNNGNSSAQNVIFTDTVPSVTTFI 2522 Query: 90 ANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTT 149 AN+ +GVP G P +G+ +G + T V ++FQV V SLP + + N + Y + Sbjct: 2523 ANTFSINGVPQSGADPSNGVNIGTITAGTTVTVSFQVTVTSLPTANPIVNFSSTSYQLVS 2582 Query: 150 PEGRHVEGEV-FSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGIL 208 P E E SN ++ + LS+ S +G +T + N G + I+ Sbjct: 2583 PP----EAETSISNPVSTQIKEAILSMTKNESVSFADIGQTAFYTTSITNVGNTDATNIV 2638 Query: 209 TTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVPALT-- 266 T +P G F+P ++ G+ P+ADP+ G+ L L P + I FQV V ++P Sbjct: 2639 FTDALPSGLTFVPNTLTVDGVLQPNADPNTGVLLATLPPNEIYSIVFQVTVNNIPPSNPA 2698 Query: 267 -AQAVVTYDADGD------TDGTKSNTVTVAVIQSGLSVSLKVDKYSAAP-GDRLGYRFT 318 A TY+ D + SNT T+ I + +S K + A G+ + + Sbjct: 2699 PNTASTTYEFTVDPVNPPVSSAATSNT-TLLQINNATIISTKTANLTFADVGNTITFTLN 2757 Query: 319 IRNSGKL-AVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDL 377 + N+G + A D + + S FV +S +G G+ +G+I G+ A+V Sbjct: 2758 LPNTGNVTATDVTIIDILDSNLSFVPNSFTANGQTIPNADLSTGVNIGSINGGNTAIVTF 2817 Query: 378 LVSIPAEADILQMPA---IQNQGSVEYTFTL-PDGRNVRERVRSNTVTTLLFSPVISIEM 433 +A ++ +P I N S Y + + P + +SNT TT + S +++ + Sbjct: 2818 ------QATVITLPTLNPISNSASTTYHYVVDPSQPPITTSNQSNTTTTQINSAILTAQK 2871 Query: 434 TGEPPMVEPGGIAEFNIAVTNSGNYPA-EVSVIQIIPQGCTLETGKVTISVHTVPESKYS 492 V+ G + + +TNSGN A V +IP G + E T++ ++P + Sbjct: 2872 NSNVSTVDIGQDITYTVTITNSGNVSATNVIFTDLIPDGTSFEPNSFTLNGTSIPNADII 2931 Query: 493 GIVSLGVMDPGQTAQLSYLV 512 V +G + P ++ +++ + Sbjct: 2932 TGVPIGDIAPNESVIVAFHI 2951 Score = 134 bits (336), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 144/523 (27%), Positives = 241/523 (46%), Gaps = 42/523 (8%) Query: 47 KSADHTSASLGETLVYTLIARNEGNAPALT-TLVDALPSGVSFVANSVLRDGVPLPGVSP 105 K+A A++G+T+ YT I N GN A T +D LP +SFV +SV + +P G P Sbjct: 1806 KTASSAFAAVGDTITYTTILTNSGNTSANTPVFIDILPPELSFVPDSVQINTIPQLGFRP 1865 Query: 106 FSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTT-PEGRHVEGEVFSNQI 164 SGI L ++ I+FQ IV S+P + N++ YS P V SN Sbjct: 1866 DSGISLDSIPVGGTTTISFQAIVGSIPATNPTLNQSSTTYSIIIDPTQPPVIETATSNP- 1924 Query: 165 TVSLLAYKLSILLASSTPTTFVGDA------VTFTLRVRNEGTRLMSGILTTLPVPEGAI 218 +L+ +I+ A+ + D +T+T+ + N G + I+ T P+P + Sbjct: 1925 --TLVQINEAIIQATKSVDRLFSDVAPGNSFLTYTVLLDNIGNATATNIIFTDPIPNNTV 1982 Query: 219 FLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVPA-------------L 265 F+ SV GG+ P +P GIPL + G +++F+V+VVS+P + Sbjct: 1983 FIEDSVRVGGVLLPGVNPANGIPLGDIIAGDFINVTFRVQVVSIPNPIFTIGPGGLNSPV 2042 Query: 266 TAQAVVTYDADGDTD------GTKSNTVTVAVIQSGLSVSLK-VDKYSAAPGDRLGYRFT 318 A + Y + T SN V+ I SG V++K V+K A D + Y T Sbjct: 2043 VNSASINYQFMTGPNLPLVSRSTTSNPVSTQ-INSGEIVAIKSVNKTFATISDTISYTIT 2101 Query: 319 IRNSGKL-AVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDL 377 + N G + + + + +P GT F+ ++ D Q+ +P GI +G I AV+ L Sbjct: 2102 LSNPGNVTSQNIIFTDTLPDGTTFISGTLTNDSGTQQIGNPANGIQIGNINPNGTAVITL 2161 Query: 378 LVSIPAEADILQMPAIQNQGSVEYTFTL-PDGRNVRERVRSNTVTTLLFSPVISIEMTGE 436 V + I + SV++ + P V + SNTV+T + S +++ + + + Sbjct: 2162 NVLVTNIPSINPISN---SSSVQFAHVVDPSQPAVSQTNVSNTVSTTINSAILTTKKSAD 2218 Query: 437 PPMVEPGGIAEFNIAVTNSGNYPA-EVSVIQIIPQGCTLETGKVTISVHTVPESKYSGIV 495 +V G + + N+GN A ++ IP T VTI ++V +S + Sbjct: 2219 KSIVSVGDTITYTTTIRNTGNTAATNITFTSAIPANTTFIPNSVTI--NSVQQSGAQPAL 2276 Query: 496 SLGV--MDPGQTAQLSYLVRVHPGYMGSALQGSSTALYLYTID 536 + + + PG+T +++ V V S++ G+ T LY YT+D Sbjct: 2277 GVNIPNIAPGETVTVTFQVNVISVSPSSSIMGNDTILYSYTVD 2319 Score = 129 bits (325), Expect = 7e-28, Method: Compositional matrix adjust. Identities = 145/526 (27%), Positives = 234/526 (44%), Gaps = 29/526 (5%) Query: 31 SNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGNAPALT-TLVDALPSGVSFV 89 SN V+T + +L++ K+ + A +G+T YT N GN A DALPSG++FV Sbjct: 2591 SNPVSTQIKEAILSMTKNESVSFADIGQTAFYTTSITNVGNTDATNIVFTDALPSGLTFV 2650 Query: 90 ANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTT 149 N++ DGV P P +G+LL + P I FQV V ++PPS N A Y FT Sbjct: 2651 PNTLTVDGVLQPNADPNTGVLLATLPPNEIYSIVFQVTVNNIPPSNPAPNTASTTYEFTV 2710 Query: 150 -PEGRHVEGEVFSNQITVSLLAYKLSILLASSTPT-TF--VGDAVTFTLRVRNEGTRLMS 205 P V SN +LL + ++++ T TF VG+ +TFTL + N G + Sbjct: 2711 DPVNPPVSSAATSN---TTLLQINNATIISTKTANLTFADVGNTITFTLNLPNTGNVTAT 2767 Query: 206 GILTTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVPAL 265 + + F+P S + G P+AD G+ + ++ G TA ++FQ V+++P L Sbjct: 2768 DVTIIDILDSNLSFVPNSFTANGQTIPNADLSTGVNIGSINGGNTAIVTFQATVITLPTL 2827 Query: 266 ---TAQAVVTYDADGD-----TDGTKSNTVTVAVIQSGLSVSLKVDKYSAAP-GDRLGYR 316 + A TY D + + T I S + + K S G + Y Sbjct: 2828 NPISNSASTTYHYVVDPSQPPITTSNQSNTTTTQINSAILTAQKNSNVSTVDIGQDITYT 2887 Query: 317 FTIRNSGKL-AVDAMLAGAIPSGTLFVWDSVHIDG--IPQRGVHPGEGIPLGTIRAGSAA 373 TI NSG + A + + IP GT F +S ++G IP + G+P+G I + Sbjct: 2888 VTITNSGNVSATNVIFTDLIPDGTSFEPNSFTLNGTSIPNADII--TGVPIGDIAPNESV 2945 Query: 374 VVDLLVSIPAEADILQMPAIQNQGSVEYTFTL-PDGRNVRERVRSNTVTTLLFSPVISIE 432 +V + +I + I NQ SV + + P V + + SN VTT + S +++ Sbjct: 2946 IVAFHI---IANEIPPINPITNQASVSFQHIVNPANLPVSKNIISNNVTTKIESAILNTI 3002 Query: 433 MTGEPPMVEPGGIAEFNIAVTNSGNYPAEVSVIQI-IPQGCTLETGKVTISVHTVPESKY 491 G+ G + +TN+GN PA ++ +P G V + +P + Sbjct: 3003 KIGDKTFATIGDTITYTTTITNTGNIPANNAIFSDPLPSWTQFVAGSVIVDGTPLPSASI 3062 Query: 492 SGIVSLGVMDPGQTAQLSYLVRV--HPGYMGSALQGSSTALYLYTI 535 V + + P QT + + V++ +P LQ + Y + Sbjct: 3063 INGVGINTISPNQTVTIIFQVQIVSNPTTFTPELQNLGFVNFQYNV 3108 Score = 127 bits (320), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 127/488 (26%), Positives = 222/488 (45%), Gaps = 27/488 (5%) Query: 46 VKSADHTSASLGETLVYTLIARNEGNAPALTTLV--DALPSGVSFVANSVLRDGVPLPGV 103 +K+ + + G+ L YT+ N GN A T L+ D +P +FV NS +G + G Sbjct: 3532 LKAVNAPQTTTGDILTYTITLENTGNIQA-TNLIFSDTIPQDTTFVENSFTLNGTAILGA 3590 Query: 104 SPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTTPEGRHVEGEVFSNQ 163 +P G+ L +A I+FQ+++ + N++ Y+ G+ E ++ Sbjct: 3591 NPNVGVTLPTLAANATHLISFQILIKDSFSRESITNQSNTTYTIQPDPGQSPITETSTSN 3650 Query: 164 ITVSLLAYKLSILLASSTPTTF-VGDAVTFTLRVRNEGTRLMSGILTTLPVPEGAIFLPG 222 I ++ + +S PTT +G + + V+N G I+ T +P G F+P Sbjct: 3651 IVITNFVQAQLTITKTSNPTTVDIGGTILYISEVKNIGNVDAINIVFTDSIPAGTTFVPD 3710 Query: 223 SVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVPALTA---QAVVTYD----- 274 SV G+ P +P+ GIP+ + + I FQV+ + P T Q+ TY Sbjct: 3711 SVTINGVLQPGVNPENGIPIGTIPANSSKTILFQVQTNNPPTETEIVNQSSATYQYVSIP 3770 Query: 275 -ADGDTDGTKSNTVTVAVIQSGLSVSLK-VDKYSAAPGDRLGYRFTIRNSGKL-AVDAML 331 A SN VT + +Q+ +S+K D A+ G + Y T++N G + A + + Sbjct: 3771 TAPPVNRSANSNIVTTS-LQNANIISVKSADITFASIGQIITYTNTLQNIGTVPANNTVF 3829 Query: 332 AGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDL---LVSIPAEADIL 388 IP GT+F+ DS+ I+ + Q G +P G+ LGTI+ + L +IP ++ Sbjct: 3830 IDNIPEGTIFIEDSLAINNVIQPGANPENGVTLGTIQPNETVTISFQVQLTNIPVGNVVI 3889 Query: 389 QMPAIQNQGSVEYTFTLPDGRNVRERVRSNTVTTLLFSPVISIEMTGEPPMVEPGGIAEF 448 + + S EY P + ++ R SN V T + + +S + + G I + Sbjct: 3890 NI----SDTSYEYQID-PSSQIIQRRSLSNAVNTEVRTANVSAIKSANRSITRIGQIITY 3944 Query: 449 NIAVTNSGNYP-AEVSVIQIIPQGCTLETGKVTIS-VHTVPESKYSGIVSLGVMDPGQTA 506 +AVTN+G P ++ I G T + + V + E+ +GI +L ++ P T Sbjct: 3945 TVAVTNAGTIPITNTLLLDAIASGTTFVPNSILVDGVPRLNENPITGI-NLDIILPNNTI 4003 Query: 507 QLSYLVRV 514 +++ V V Sbjct: 4004 IVTFQVSV 4011 Score = 126 bits (316), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 135/462 (29%), Positives = 216/462 (46%), Gaps = 25/462 (5%) Query: 30 YSNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGNAPALTT-LVDALPSGVSF 88 +SN V+T + +TL KS + A++GET+ YT++ N GN A L D LP+G Sbjct: 735 FSNLVSTQINNANVTLTKSTNKQFATIGETISYTILITNSGNMAANNVQLTDPLPNGTIL 794 Query: 89 VANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFT 148 +V +GV L V + +G + ++FQV V+++ + N A A Y +T Sbjct: 795 TPGTVTLNGV-LQNVDSLVALPIGTIPGGATFTLSFQVTVINITTQNPIINNAFASYLYT 853 Query: 149 -TPEGRHVEGEVFSNQITVSLLAYKLSILLAS-STPTTF--VGDAVTFTLRVRNEGTRLM 204 P SN +T ++ +L+ L A+ S TF VGD +T+T + N+G Sbjct: 854 VNPNLPPTSKTANSNSVTSTI---RLANLHANKSVDKTFAEVGDVLTYTFALTNDGNVAA 910 Query: 205 SGILTTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVPA 264 + +L + + G F+P SVI G+ P P I + ++ T SFQV + S+P Sbjct: 911 NNVLLSDSIANGTAFVPNSVIVNGVTQPGVTP-TSINIGSINANTTITASFQVVITSIPN 969 Query: 265 ---LTAQAVVTYD--ADGDTDGTKSNTVTVAV---IQSGLSVSLK-VDKYSAAPGDRLGY 315 ++ A ++Y+ D + NT + + +S K VD+ A GD L Y Sbjct: 970 PNPISNSASISYNFIVDPNASPVSKNTTSTTTFTQVNDANVISAKTVDRAFATVGDILTY 1029 Query: 316 RFTIRNSGKLAVDA-MLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAV 374 T+ N+G ++ D+ P GT F+ ++ I+G+ Q P G+PL +I A + Sbjct: 1030 TVTLTNAGSVSADSPTFVDTNPDGTTFIPNTFLINGVLQNNADPNIGVPLPSIAANGSLT 1089 Query: 375 VDLLVSIPAEADILQMPAIQNQGSVEYTFTL-PDGRNVRERVRSNTVTTLLFSPVISIEM 433 V V++ + Q P I N S +Y+F L P E SNTV+T + + I Sbjct: 1090 VSYQVTVTSLP--TQNPTI-NSSSTQYSFILNPGDPPTVETSVSNTVSTQINLANVVIVK 1146 Query: 434 TGEPPMVEPGGIAEFNIAVTNSGNYPA-EVSVIQIIPQGCTL 474 + + + G + I + N GN A V V IIP G T+ Sbjct: 1147 EVDLTIADVGQPITYTIYLANLGNTIANNVIVTDIIPNGTTI 1188 Score = 124 bits (311), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 135/503 (26%), Positives = 235/503 (46%), Gaps = 23/503 (4%) Query: 29 TYSNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGNAPALTTL-VDALPSGVS 87 T SN V+T + + +KS + T A++ +T+ YT+ N GN + + D LP G + Sbjct: 2065 TTSNPVSTQINSGEIVAIKSVNKTFATISDTISYTITLSNPGNVTSQNIIFTDTLPDGTT 2124 Query: 88 FVANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSF 147 F++ ++ D +P +GI +G + P I V+V ++P + N + ++ Sbjct: 2125 FISGTLTNDSGTQQIGNPANGIQIGNINPNGTAVITLNVLVTNIPSINPISNSSSVQFAH 2184 Query: 148 TT-PEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSG 206 P V SN ++ ++ + L+ ++ VGD +T+T +RN G + Sbjct: 2185 VVDPSQPAVSQTNVSNTVSTTINSAILTTKKSADKSIVSVGDTITYTTTIRNTGNTAATN 2244 Query: 207 ILTTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVPALT 266 I T +P F+P SV + A P G+ +P + PG+T ++FQV V+SV + Sbjct: 2245 ITFTSAIPANTTFIPNSVTINSVQQSGAQPALGVNIPNIAPGETVTVTFQVNVISVSPSS 2304 Query: 267 AQA-----VVTYDADGD----TDGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGD-RLGYR 316 + + +Y D + T T +N T V+ + +++ VD+ GD Sbjct: 2305 SIMGNDTILYSYTVDPNSAPATTSTSTNIATNPVLDAMITMVKSVDQTLVTLGDTITYTT 2364 Query: 317 FTIRNSGKLAVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVD 376 N A + IP+GT F+ DSV I+G+ Q G++P GI +G+I S+ + Sbjct: 2365 NLTNNGNTNATNITFTDLIPNGTTFITDSVTINGLTQIGLNPNTGITIGSIAPNSS--IS 2422 Query: 377 LLVSIPAEADILQMPAIQNQGSVEYTFTL-PDGRNVRERVRSNTV-TTLLFSPVISIEMT 434 + + A + +Q P I N + YTF P+ V V SNTV TT+ + ++S++ Sbjct: 2423 IAFQVTATSTPVQNP-IANSATASYTFIADPNAPIVSRNVTSNTVFTTINTANILSLKQV 2481 Query: 435 GEPPMVEPGGIAEFNIAVTNSGNYPAE-VSVIQIIPQGCTLETGKVTISVHTVPESKY-- 491 + G + + +TN+GN A+ V +P T T S++ VP+S Sbjct: 2482 -DKSFSRIGDTLTYTVVLTNNGNSSAQNVIFTDTVPSVTTFIAN--TFSINGVPQSGADP 2538 Query: 492 SGIVSLGVMDPGQTAQLSYLVRV 514 S V++G + G T +S+ V V Sbjct: 2539 SNGVNIGTITAGTTVTVSFQVTV 2561 Score = 123 bits (309), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 108/428 (25%), Positives = 197/428 (46%), Gaps = 17/428 (3%) Query: 47 KSADHTSASLGETLVYTLIARNEGNAPALTTL-VDALPSGVSFVANSVLRDGVPLPGVSP 105 KS + +GETL Y++ N GN A + D +PSG +F++ SV +GV G +P Sbjct: 488 KSVNKLFTDIGETLTYSIALANIGNIAATNVIYTDPIPSGTTFISGSVTVNGVTQAGANP 547 Query: 106 FSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFT-TPEGRHVEGEVFSNQI 164 +GI +G++A + I+FQV+V S+P + + N Y + P V G +N + Sbjct: 548 ANGISIGSIAANSTTTISFQVLVPSIPQTNPILNSGTTTYQYIPVPNQPAVSGTDKTNIV 607 Query: 165 TVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGILTTLPVPEGAIFLPGSV 224 + + +++ A +GD +T+T+ G + ++ +P G F+ S+ Sbjct: 608 STQVNNATVTMTKAVDKNFADIGDTLTYTVSFTATGNTNANNVIFIDVIPTGTTFVLNSL 667 Query: 225 ISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVPA---------LTAQAVVTYDA 275 G A+P G+ + + G T +++FQV V ++PA + Q V Sbjct: 668 TIDGTTQVGANPANGVNIGSIPSGTTKNVAFQVVVNTIPASNVVSNGSSASYQYTVNPSQ 727 Query: 276 DGDTDGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTIRNSGKLAVDAM-LAGA 334 T SN V+ + + ++++ +K A G+ + Y I NSG +A + + L Sbjct: 728 SPVTKNIFSNLVSTQINNANVTLTKSTNKQFATIGETISYTILITNSGNMAANNVQLTDP 787 Query: 335 IPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDLLVSIPAEADILQMPAIQ 394 +P+GT+ +V ++G+ Q V +P+GTI G+ + V++ +I I Sbjct: 788 LPNGTILTPGTVTLNGVLQN-VDSLVALPIGTIPGGATFTLSFQVTV---INITTQNPII 843 Query: 395 NQGSVEYTFTL-PDGRNVRERVRSNTVTTLLFSPVISIEMTGEPPMVEPGGIAEFNIAVT 453 N Y +T+ P+ + SN+VT+ + + + + E G + + A+T Sbjct: 844 NNAFASYLYTVNPNLPPTSKTANSNSVTSTIRLANLHANKSVDKTFAEVGDVLTYTFALT 903 Query: 454 NSGNYPAE 461 N GN A Sbjct: 904 NDGNVAAN 911 Score = 97.4 bits (241), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 66/229 (28%), Positives = 122/229 (53%), Gaps = 3/229 (1%) Query: 38 VVGPVLTLVKSADHTSASLGETLVYTLIARNEGNAPALTT-LVDALPSGVSFVANSVLRD 96 V+ P++ + K+AD + +G+ + +TL N P ++T ++D +P+G +F+ NSV + Sbjct: 4705 VIDPMVRIEKTADKSIVVIGDIITFTLAVFNHSPIPTISTSVIDTIPAGTTFIENSVTIN 4764 Query: 97 GVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFT-TPEGRHV 155 G P+P V P +GI +G+++ T I FQV+ S+P + + N A +F TP+ + Sbjct: 4765 GTPVPNVRPDTGINIGSLSAGTVATITFQVLATSIPSNSTIINSATVTAAFQLTPQDPII 4824 Query: 156 EGEVFSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGILTTLPVPE 215 V SN + + + ++ +S + ++ +T+R+ N +S I +P Sbjct: 4825 TFIVNSNIVRIPVQFITATVTKNASVSSAYLNQYFDYTVRITNTSEISLSNISLQDTIPA 4884 Query: 216 GAIFLPGSVISGGIYSPDADPDKGIPLPP-LDPGKTADISFQVRVVSVP 263 G F+ G+V G SP A+P+ G + L+P +T + F V+V+S P Sbjct: 4885 GLQFINGTVFINGERSPLANPNIGFLVATNLEPNETIIVLFTVQVISPP 4933 >C2PTW7.1 C2PTW7_BACCE Cell surface protein Length = 5010 Score = 197 bits (501), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 164/523 (31%), Positives = 252/523 (48%), Gaps = 23/523 (4%) Query: 31 SNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGNAPALT-TLVDALPSGVSFV 89 SNTVNT VV L+++K+ D S T+ YT++ +N GN A T L D +P G +F+ Sbjct: 3385 SNTVNTAVVDASLSVIKNTDSLVQSTNGTITYTVVVQNNGNTTANTVNLTDLVPEGTTFI 3444 Query: 90 ANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTT 149 NSV + V +PG P GI L A+AP V + FQVIV S+P + N AR Y+F Sbjct: 3445 PNSVTINSVSVPGADPNVGIPLNAIAPSEIVTVTFQVIVQSIPSVNPISNTARIDYTFIA 3504 Query: 150 -PEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGIL 208 P + + SN + + L A + GD +T+T+ + N G + ++ Sbjct: 3505 DPTSPIISRTITSNPAFTQISDANVLSLKAVNAQQATTGDILTYTITLENTGNIPATNLI 3564 Query: 209 TTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRV---VSVPAL 265 + +PEG F+ S G A+P+ G+ LP L T ISFQ+ + S ++ Sbjct: 3565 FSDTIPEGTTFVENSFTLNGTAILGANPNVGVTLPNLAANATHLISFQILINDPFSQESI 3624 Query: 266 TAQAVVTYDADGD------TDGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTI 319 T Q+ TY D T+ + SN V +Q+ L ++ + + G + Y + Sbjct: 3625 TNQSNTTYTIQPDPSQPPITETSTSNIVITNFVQAQLIITKTSNPITVDIGGTILYISEV 3684 Query: 320 RNSGKL-AVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDLL 378 +N G + A++ + +IP+GT FV DSV I+G+ Q GVHP GIP+GTI A S+ + Sbjct: 3685 KNIGNVDAINIIFTDSIPAGTTFVPDSVTINGVLQPGVHPENGIPIGTIPANSSKTILFQ 3744 Query: 379 VSI---PAEADILQMPAIQNQGSVEYTF-TLPDGRNVRERVRSNTVTTLLFSPVISIEMT 434 V P E +I+ NQ S Y + ++P V SN VTT L + I + Sbjct: 3745 VQTNNPPTETEIV------NQSSATYQYVSIPTAPPVNRSANSNIVTTSLQNANIISVKS 3798 Query: 435 GEPPMVEPGGIAEFNIAVTNSGNYPAEVSV-IQIIPQGCTLETGKVTISVHTVPESKYSG 493 + V G I + + N G PA +V I IP+G ++I+ P + Sbjct: 3799 ADVTFVSIGQIITYTNTLQNIGTIPANNTVFIDNIPEGTIFIEDSLSINNVIQPGANPEN 3858 Query: 494 IVSLGVMDPGQTAQLSYLVRVHPGYMGSALQGSSTALYLYTID 536 V+LG + P +T +S+ V++ G+ + S Y Y ID Sbjct: 3859 GVTLGTIQPNETVTISFQVQLTNIPSGNTVINLSDTSYEYQID 3901 Score = 171 bits (432), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 158/540 (29%), Positives = 252/540 (46%), Gaps = 40/540 (7%) Query: 41 PVLTLVKSADHTSASLGETLVYTLIARNEGNAPALT-TLVDALPSGVSFVANSVLRDGVP 99 P + KS + + A++G+ L YT+ N G PA T D LP+G SF+ SV D VP Sbjct: 350 PNIQATKSVNKSVATIGDILTYTVTVPNTGLLPANNVTFTDVLPNGTSFIPGSVTIDNVP 409 Query: 100 LPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTTPEGRHVEGEV 159 +P +GI LG + + +AFQ VVSLP + N A + +T G G Sbjct: 410 QTNANPVAGISLGTINNGSSRTVAFQATVVSLPSQNPISNTANITFQYTPIAG----GTT 465 Query: 160 FSNQITVSLLAYKLSILLASSTPT-----TFVGDAVTFTLRVRNEGTRLMSGILTTLPVP 214 F+ T + ++++ + T + T +G+ +T+++ + N G + ++ T P+P Sbjct: 466 FNGLATSNSAGTQINLADINGTKSVNKLFTDIGETLTYSIALANIGNIAATNVIYTDPIP 525 Query: 215 EGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVPA---LTAQAVV 271 G F+PGSV G+ A+P GI + + T ISFQV V S+P + Sbjct: 526 SGTTFIPGSVTVNGVTQGGANPANGISIGSIAANSTTTISFQVFVPSIPQTNPILNSGTT 585 Query: 272 TYD--------ADGDTDGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTIRNSG 323 TY A TD T N V+ V + ++++ VDK A GD L Y +G Sbjct: 586 TYQYIPVPNQPAVSGTDTT--NIVSTQVNNATVTMTKAVDKNYADIGDTLTYTVAFTGTG 643 Query: 324 KL-AVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDLLV--- 379 A + + IP+GT FV +S+ IDG Q G +P G+ +G+I G+ V V Sbjct: 644 NTNANNVIFTDVIPTGTTFVLNSLTIDGSTQVGANPANGVNIGSIPTGTTKSVSFQVVVN 703 Query: 380 SIPAEADILQMPAIQNQGSVEYTFTL-PDGRNVRERVRSNTVTTLLFSPVISIEMTGEPP 438 +IPA A+ N S Y +T+ P + + + SN VTT + + +++ + Sbjct: 704 TIPASN------AVSNGSSASYQYTVNPSQSPIMKNISSNVVTTQINNANLTLTKSTNKQ 757 Query: 439 MVEPGGIAEFNIAVTNSGNYPA-EVSVIQIIPQGCTLETGKVTISVHTVPESKYSGI-VS 496 G + I +TNSGN A V + +P G L G VT+ + V ++ S + + Sbjct: 758 FATIGETISYTILITNSGNTAANNVQLTDPLPNGTILTLGSVTL--NGVLQNVDSLVALP 815 Query: 497 LGVMDPGQTAQLSYLVRVHPGYMGSALQGSSTALYLYTIDGRR--YSGEARSNSYKLMIE 554 +G + G T LS+ V V + + ++ + Y+YT++ S A SNS I Sbjct: 816 IGTIPGGATFTLSFQVTVINITAQNPIINNAFSSYIYTVNPSLPPTSKTANSNSVTSTIR 875 Score = 169 bits (429), Expect = 5e-40, Method: Compositional matrix adjust. Identities = 141/508 (27%), Positives = 239/508 (47%), Gaps = 25/508 (4%) Query: 42 VLTLVKSADHTSASLGETLVYTLIARNEGNAPALT-TLVDALPSGVSFVANSVLRDGVPL 100 +L+ VK+A+ A++G+T+ YT++ +N GN A D +P+G +FV NS +G + Sbjct: 3132 ILSAVKTANTAFANIGDTITYTVLIQNSGNTNATNLNFSDLIPAGTTFVENSFSVNGSII 3191 Query: 101 PGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTT-PEGRHVEGEV 159 PG P +G+ +G V+ + + + FQV+V S PPS + N ++F P V + Sbjct: 3192 PGADPNNGVNIGTVSTNSSLTVTFQVMVASTPPSNPITNVGSIQFTFIVDPAAPPVTSTI 3251 Query: 160 FSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGILTTLPVPEGAIF 219 SN + + ++ +L ++ +GD +T+T + N G + +L VP GA+F Sbjct: 3252 NSNGASTQINNATVTTVLEANRSIVSIGDIITYTATLTNTGNFPANSVLLINGVPVGAVF 3311 Query: 220 LPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVP---ALTAQAVVTYDAD 276 +P SV G+ P+A P GIP+ + PG A I+FQ S+P A+ QA+ +Y Sbjct: 3312 VPNSVTLNGMSLPNASPTLGIPVGIIAPGDFATITFQFLASSIPPQGAIINQAITSYTYI 3371 Query: 277 GD------TDGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTIRNSGKLAVDAM 330 D T + SNTV AV+ + LSV D + + Y ++N+G + + Sbjct: 3372 VDPSQPPVTATSSSNTVNTAVVDASLSVIKNTDSLVQSTNGTITYTVVVQNNGNTTANTV 3431 Query: 331 -LAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDLLV---SIPAEAD 386 L +P GT F+ +SV I+ + G P GIPL I V V SIP+ Sbjct: 3432 NLTDLVPEGTTFIPNSVTINSVSVPGADPNVGIPLNAIAPSEIVTVTFQVIVQSIPS--- 3488 Query: 387 ILQMPAIQNQGSVEYTFTL-PDGRNVRERVRSN-TVTTLLFSPVISIEMTGEPPMVEPGG 444 + I N ++YTF P + + SN T + + V+S++ G Sbjct: 3489 ---VNPISNTARIDYTFIADPTSPIISRTITSNPAFTQISDANVLSLKAVNA-QQATTGD 3544 Query: 445 IAEFNIAVTNSGNYPAEVSVI-QIIPQGCTLETGKVTISVHTVPESKYSGIVSLGVMDPG 503 I + I + N+GN PA + IP+G T T++ + + + V+L + Sbjct: 3545 ILTYTITLENTGNIPATNLIFSDTIPEGTTFVENSFTLNGTAILGANPNVGVTLPNLAAN 3604 Query: 504 QTAQLSYLVRVHPGYMGSALQGSSTALY 531 T +S+ + ++ + ++ S Y Sbjct: 3605 ATHLISFQILINDPFSQESITNQSNTTY 3632 Score = 169 bits (427), Expect = 9e-40, Method: Compositional matrix adjust. Identities = 150/542 (27%), Positives = 249/542 (45%), Gaps = 32/542 (5%) Query: 17 VLYS-----SAAGADVITYSNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGN 71 +LYS S A T +N V PV+ ++T+VKS D T +LG+T+ YT I +N GN Sbjct: 2312 ILYSYTVDPSGAPITTSTSTNIVTNPVLDAMITMVKSVDQTLVTLGDTITYTTILKNSGN 2371 Query: 72 APALT-TLVDALPSGVSFVANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVS 130 A T D +P G +F+ +S+ DG+ G++P +GI +G++AP + + IAFQV S Sbjct: 2372 TNATNITFTDLIPDGTTFITDSITIDGITQIGLNPNTGITIGSIAPNSSISIAFQVTATS 2431 Query: 131 LPPSLELGNRARAVYSFTT-PEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTF--VG 187 P + N A A Y+F P V V S T +IL + F +G Sbjct: 2432 TPVQNPIANSATASYTFIADPNAPIVSRNVTS--NTTFTTINTATILSSKQVDKAFSHIG 2489 Query: 188 DAVTFTLRVRNEGTRLMSGILTTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDP 247 D +T+T+ + N G ++ T VP G F+ + GI A+P G+ + P+ Sbjct: 2490 DTLTYTVTLTNNGNSSAQNVIFTDTVPSGTTFIANTFSINGIPQSGANPTNGVNIGPITA 2549 Query: 248 GKTADISFQVRVVSVPALTAQAVVTYDADG-------DTDGTKSNTVTVAVIQSGLSVSL 300 G T ++SF+V V S+P T +V + + D + + SN V+ + ++ LS++ Sbjct: 2550 GSTVNVSFRVNVTSLP--TENPIVNFSSTSYQLVSPPDAETSISNPVSTQIREAILSMTK 2607 Query: 301 KVDKYSAAPGDRLGYRFTIRNSGKL-AVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPG 359 A G Y +I N G A + + +PSG F+ +++ +DGI Q P Sbjct: 2608 NESLSFADVGQTAFYTTSITNVGNTDATNIVFTDVLPSGLTFIPNTLTVDGILQPNADPN 2667 Query: 360 EGIPLGTIRAGSAAVVDLLVSIPAEADILQMPAIQ---NQGSVEYTFTL-PDGRNVRERV 415 G+ L + + SI + + +P I N S Y FT+ P V Sbjct: 2668 TGVLLAALPPNE------IYSIVFQVTVNSIPPINPAPNTASTTYEFTVDPGNPPVSNTA 2721 Query: 416 RSNTVTTLLFSPVISIEMTGEPPMVEPGGIAEFNIAVTNSGNYPA-EVSVIQIIPQGCTL 474 SNT + + I T + G F + + N+GN A +V++I I+ + Sbjct: 2722 SSNTTLLQINNANIISTKTANLTFADVGNTITFTLNLPNTGNVAATDVTIIDILDSNLSF 2781 Query: 475 ETGKVTISVHTVPESKYSGIVSLGVMDPGQTAQLSYLVRVHPGYMGSALQGSSTALYLYT 534 T++ T+P + S V++G ++ G TA +++ V + + ++ Y Y Sbjct: 2782 IPNSFTVNGQTIPNADLSTGVNIGSINGGNTAIVTFQATVTTLPTLNPISNFASTTYHYV 2841 Query: 535 ID 536 +D Sbjct: 2842 VD 2843 Score = 165 bits (417), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 152/519 (29%), Positives = 238/519 (45%), Gaps = 21/519 (4%) Query: 31 SNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGNAPALTTL-VDALPSGVSFV 89 SN +T + +T V A+ + S+G+ + YT N GN PA + L ++ +P G FV Sbjct: 3253 SNGASTQINNATVTTVLEANRSIVSIGDIITYTATLTNTGNFPANSVLLINGVPVGAVFV 3312 Query: 90 ANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTT 149 NSV +G+ LP SP GI +G +AP I FQ + S+PP + N+A Y++ Sbjct: 3313 PNSVTLNGMSLPNASPTLGIPVGIIAPGDFATITFQFLASSIPPQGAIINQAITSYTYIV 3372 Query: 150 -PEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGIL 208 P V SN + +++ LS++ + + +T+T+ V+N G + + Sbjct: 3373 DPSQPPVTATSSSNTVNTAVVDASLSVIKNTDSLVQSTNGTITYTVVVQNNGNTTANTVN 3432 Query: 209 TTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVPAL--- 265 T VPEG F+P SV + P ADP+ GIPL + P + ++FQV V S+P++ Sbjct: 3433 LTDLVPEGTTFIPNSVTINSVSVPGADPNVGIPLNAIAPSEIVTVTFQVIVQSIPSVNPI 3492 Query: 266 --TAQAVVTYDADGDTDGTKSNTVT----VAVIQSGLSVSLK-VDKYSAAPGDRLGYRFT 318 TA+ T+ AD T S T+T I +SLK V+ A GD L Y T Sbjct: 3493 SNTARIDYTFIAD-PTSPIISRTITSNPAFTQISDANVLSLKAVNAQQATTGDILTYTIT 3551 Query: 319 IRNSGKL-AVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDL 377 + N+G + A + + + IP GT FV +S ++G G +P G+ L + A + ++ Sbjct: 3552 LENTGNIPATNLIFSDTIPEGTTFVENSFTLNGTAILGANPNVGVTLPNLAANATHLISF 3611 Query: 378 LVSIPAEADILQMPAIQNQGSVEYTFTLPDGRN--VRERVRSNTVTTLLFSPVISIEMTG 435 + I D +I NQ + YT PD + E SN V T + I T Sbjct: 3612 QILI---NDPFSQESITNQSNTTYTIQ-PDPSQPPITETSTSNIVITNFVQAQLIITKTS 3667 Query: 436 EPPMVEPGGIAEFNIAVTNSGNYPA-EVSVIQIIPQGCTLETGKVTISVHTVPESKYSGI 494 P V+ GG + V N GN A + IP G T VTI+ P Sbjct: 3668 NPITVDIGGTILYISEVKNIGNVDAINIIFTDSIPAGTTFVPDSVTINGVLQPGVHPENG 3727 Query: 495 VSLGVMDPGQTAQLSYLVRVHPGYMGSALQGSSTALYLY 533 + +G + + + + V+ + + + S+A Y Y Sbjct: 3728 IPIGTIPANSSKTILFQVQTNNPPTETEIVNQSSATYQY 3766 Score = 163 bits (413), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 147/521 (28%), Positives = 243/521 (46%), Gaps = 25/521 (4%) Query: 11 VSNQSMVLYSSAAGADVITYSNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEG 70 + NQS Y+ G + I+ SN T V+ + K+ A L + YT+ N G Sbjct: 4284 IQNQSTSRYT-INGEEQISTSNITFTEVISANVIATKTTPIQYADLQTIIPYTISIINNG 4342 Query: 71 NAPALTTLV-DALPSGVSFVANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVV 129 N +V D +P+ +F+ NSV+ +G P +P SGI + + P T I FQV V+ Sbjct: 4343 NIQVENIIVTDIIPANTNFIENSVIVNGNARPNDNPLSGIPIDNIPPNTTATILFQVRVI 4402 Query: 130 SLPPSLELGNRARAVYSFTTPEGRHVEGEVFSN----QITVSLLAYKLSILLASSTPTTF 185 S+P + + N + Y +T P+ + + S+ +I + L + LA +T Sbjct: 4403 SIPQTNPISNTSTIEYEYTVPDQPPITETIISSTAVTEIHHANLDSNKDVDLAFAT---- 4458 Query: 186 VGDAVTFTLRVRNEGTRLMSGILTTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPL 245 VGD +T+T+ + G + ++ +P+G F+ SVI G P +P GIP+ + Sbjct: 4459 VGDTLTYTITLNQTGNVSANDVIIQDIIPQGTTFIENSVIVNGETLPGVNPVSGIPIGTI 4518 Query: 246 DPGKTADISFQVRVVSVPA---LTAQAVVTYDADGDTDG-----TKSNTVTVAVIQSGLS 297 G A SFQV V S+P L +A+ T++ + + T + +Q+ Sbjct: 4519 IVGGNAIASFQVTVTSIPTPNELNNKAITTFNYIVNPNNLPVTNTTTTNTVTTTVQNDNV 4578 Query: 298 VSLK-VDKYSAAPGDRLGYRFTIRNSGKLAVDAMLA-GAIPSGTLFVWDSVHIDGIPQRG 355 V+ K V+ +A P L Y TI NSG + ++ +LA +P T FV SV I+GI Q Sbjct: 4579 VATKSVNATNALPSQTLTYTITITNSGNVTIEDLLAIDTVPVDTTFVTSSVTINGINQPN 4638 Query: 356 VHPGEGIPLGTIRAGSAAVVDLLVSIPAEADILQMPAIQNQGSVEYTFTL-PDGRNVRER 414 +P GI LG + + ++ ++I + +PAI N SV YT + P+ + Sbjct: 4639 ANPENGITLGNLAPNESVIITFQITISSST---LLPAINNDASVSYTVIIDPNEPPITMT 4695 Query: 415 VRSNTVTTLLFSPVISIEMTGEPPMVEPGGIAEFNIAVTNSGNYPA-EVSVIQIIPQGCT 473 ++N VTT + P++ I + G I F + V N P SV+ +IP G T Sbjct: 4696 KQTNVVTTTIVDPMVGIAKIANKSITITGDIITFTLDVFNHSPIPTVNTSVLDMIPAGTT 4755 Query: 474 LETGKVTISVHTVPESKYSGIVSLGVMDPGQTAQLSYLVRV 514 VTI+ +P + +++G + A +++ V V Sbjct: 4756 FIENSVTINGTQIPNIRPDTGINIGALPADGVATITFKVLV 4796 Score = 155 bits (393), Expect = 8e-36, Method: Compositional matrix adjust. Identities = 145/537 (27%), Positives = 246/537 (45%), Gaps = 30/537 (5%) Query: 17 VLYSSAAGADVITYSNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGNAPALT 76 V+ +A V T NT N +V LT SAD +G+ ++Y I N GN PA Sbjct: 1255 VVVKNATSNIVTTQINTAN--IVATKLTSTNSAD-----VGDVILYATILTNNGNIPASN 1307 Query: 77 -TLVDALPSGVSFVANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSL 135 T D +P+G F+ N+V + VP+ +P +GI +G + + +AFQV+V ++P Sbjct: 1308 VTFTDIIPAGTLFIPNTVTINNVPIANANPANGIFIGTIGANSSRTVAFQVLVPTIPAVN 1367 Query: 136 ELGNRARAVYSFT-TPEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTL 194 + N++ + +T P V V SN + ++ ++ ++ V D +T+T Sbjct: 1368 PITNQSGTTFQYTYDPSKPAVMQMVASNTVQTTINNASIAATKSADKQFANVNDIITYTT 1427 Query: 195 RVRNEGTRLMSGILTTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADIS 254 + N G L S I+ T +P G F+P SV G P+ +P GI + P++P IS Sbjct: 1428 TLTNNGNTLASNIVFTDAIPSGTSFIPNSVTVNGTTLPNVNPANGIAIDPINPNANTTIS 1487 Query: 255 FQVRVVSVPA---------LTAQAVVTYDADGDTDGTKSNTVTVAVIQSGLSVSLKVDKY 305 FQ++V S+P+ T Q +V + + SN +T + + + + V+ Sbjct: 1488 FQIKVNSIPSPNPIPNQSNTTYQYIVNPNLPPASANALSNVITTQINNATIVATKSVNTP 1547 Query: 306 SAAPGDRLGYRFTIRNSGKLAVDA-MLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPL 364 +AA GD + Y + N+G + A +L + +G F+ +SV I+ +PQ G+ P GI L Sbjct: 1548 TAAIGDIVTYTIAVTNTGNIPASANVLTDGLGAGASFIQNSVTINNVPQPGLDPSLGIHL 1607 Query: 365 GTIRAGSAAVVDLLVSIPAEADILQMP---AIQNQGSVEYTFTL-PDGRNVRERVRSNTV 420 I G+ + +A IL +P + N V Y +T+ P+ +NT Sbjct: 1608 ADIPPGNTVFITF------QAQILAIPPSGTLTNNALVNYEYTVNPNQSPAVGSTITNTT 1661 Query: 421 TTLLFSPVISIEMTGEPPMVEPGGIAEFNIAVTNSGNYPA-EVSVIQIIPQGCTLETGKV 479 T + +SI T G F +TNSGN A V +IP G T Sbjct: 1662 ITPIIDATLSINKTVNSTFATIGDTLTFTSTITNSGNTTANNVIFTDLIPDGTTFIPNSF 1721 Query: 480 TISVHTVPESKYSGIVSLGVMDPGQTAQLSYLVRVHPGYMGSALQGSSTALYLYTID 536 T++ T+P + +++G ++ + LS+ V + + + S+ Y + +D Sbjct: 1722 TVNGTTIPNANPQNGINIGNINSNASVILSFQVNIATIPNPNPIPNKSSVQYSFIVD 1778 Score = 146 bits (368), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 129/474 (27%), Positives = 213/474 (44%), Gaps = 27/474 (5%) Query: 78 LVDALPSGVSFVANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLEL 137 D +P G +F+ SVL + +P +P +GIL+G +AP + + F VV+LP S + Sbjct: 4225 FTDNIPDGTTFIDGSVLVNNIPQLNANPSTGILVGTIAPDISIPVTFSATVVALPASGRI 4284 Query: 138 GNRARAVYSFTTPEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTF--VGDAVTFTLR 195 N++ + Y+ E F+ I+ +++A K +TP + + + +T+ Sbjct: 4285 QNQSTSRYTINGEEQISTSNITFTEVISANVIATK-------TTPIQYADLQTIIPYTIS 4337 Query: 196 VRNEGTRLMSGILTTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISF 255 + N G + I+ T +P F+ SVI G P+ +P GIP+ + P TA I F Sbjct: 4338 IINNGNIQVENIIVTDIIPANTNFIENSVIVNGNARPNDNPLSGIPIDNIPPNTTATILF 4397 Query: 256 QVRVVSVPA---LTAQAVVTY-----DADGDTDGTKSNTVTVAVIQSGLSVSLKVDKYSA 307 QVRV+S+P ++ + + Y D T+ S+T + + L + VD A Sbjct: 4398 QVRVISIPQTNPISNTSTIEYEYTVPDQPPITETIISSTAVTEIHHANLDSNKDVDLAFA 4457 Query: 308 APGDRLGYRFTIRNSGKL-AVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGT 366 GD L Y T+ +G + A D ++ IP GT F+ +SV ++G GV+P GIP+GT Sbjct: 4458 TVGDTLTYTITLNQTGNVSANDVIIQDIIPQGTTFIENSVIVNGETLPGVNPVSGIPIGT 4517 Query: 367 IRAGSAAVVDLLV---SIPAEADILQMPAIQNQGSVEYTFTLPDGRNVRERVRSNTVTTL 423 I G A+ V SIP + L AI + LP + TV Sbjct: 4518 IIVGGNAIASFQVTVTSIPTPNE-LNNKAITTFNYIVNPNNLPVTNTTTTNTVTTTVQND 4576 Query: 424 LFSPVISIEMTGEPPMVEPGGIAEFNIAVTNSGNYPAE-VSVIQIIPQGCTLETGKVTIS 482 S+ T P + I +TNSGN E + I +P T T VTI+ Sbjct: 4577 NVVATKSVNATNA----LPSQTLTYTITITNSGNVTIEDLLAIDTVPVDTTFVTSSVTIN 4632 Query: 483 VHTVPESKYSGIVSLGVMDPGQTAQLSYLVRVHPGYMGSALQGSSTALYLYTID 536 P + ++LG + P ++ +++ + + + A+ ++ Y ID Sbjct: 4633 GINQPNANPENGITLGNLAPNESVIITFQITISSSTLLPAINNDASVSYTVIID 4686 Score = 140 bits (354), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 113/391 (28%), Positives = 193/391 (49%), Gaps = 29/391 (7%) Query: 31 SNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGNAPALTTL-VDALPSGVSFV 89 +N V+T V +T+ K+ D A +G+TL YT+ GN A + D +P+G +FV Sbjct: 604 TNIVSTQVNNATVTMTKAVDKNYADIGDTLTYTVAFTGTGNTNANNVIFTDVIPTGTTFV 663 Query: 90 ANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFT- 148 NS+ DG G +P +G+ +G++ T ++FQV+V ++P S + N + A Y +T Sbjct: 664 LNSLTIDGSTQVGANPANGVNIGSIPTGTTKSVSFQVVVNTIPASNAVSNGSSASYQYTV 723 Query: 149 TPEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGIL 208 P + + SN +T + L++ +++ +G+ +++T+ + N G + + Sbjct: 724 NPSQSPIMKNISSNVVTTQINNANLTLTKSTNKQFATIGETISYTILITNSGNTAANNVQ 783 Query: 209 TTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVPALTAQ 268 T P+P G I GSV G+ + D +P+ + G T +SFQV V+++ TAQ Sbjct: 784 LTDPLPNGTILTLGSVTLNGVLQ-NVDSLVALPIGTIPGGATFTLSFQVTVINI---TAQ 839 Query: 269 AVVTYDADGD------------TDGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYR 316 + +A + SN+VT + + L + V + A GD L Y Sbjct: 840 NPIINNAFSSYIYTVNPSLPPTSKTANSNSVTSTIRLANLHANKSVSQTFAEVGDVLTYT 899 Query: 317 FTIRNSGKL-AVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAG---SA 372 F + N G + A + +L+ +I +GT FV +SV ++G+ Q G P I +G+I A +A Sbjct: 900 FALTNDGNVTANNVLLSDSIANGTSFVPNSVIVNGVTQPGATPAS-INIGSINANTTITA 958 Query: 373 AVVDLLVSIPAEADILQMPAIQNQGSVEYTF 403 + L+ SIP IL N S+ Y F Sbjct: 959 SFQILITSIPNPNPIL------NSASISYNF 983 Score = 140 bits (352), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 141/539 (26%), Positives = 248/539 (46%), Gaps = 34/539 (6%) Query: 1 MIRDSRLQPVVSNQSMVLYS-----SAAGADVITYSNTVNTPVVGPVLTLVKSADHTSAS 55 +I D Q ++NQS Y+ S + SN V T V L + K+++ + Sbjct: 3614 LINDPFSQESITNQSNTTYTIQPDPSQPPITETSTSNIVITNFVQAQLIITKTSNPITVD 3673 Query: 56 LGETLVYTLIARNEGNAPALTTL-VDALPSGVSFVANSVLRDGVPLPGVSPFSGILLGAV 114 +G T++Y +N GN A+ + D++P+G +FV +SV +GV PGV P +GI +G + Sbjct: 3674 IGGTILYISEVKNIGNVDAINIIFTDSIPAGTTFVPDSVTINGVLQPGVHPENGIPIGTI 3733 Query: 115 APQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTT-PEGRHVEGEVFSNQITVSLLAYKL 173 + I FQV + P E+ N++ A Y + + P V SN +T SL Sbjct: 3734 PANSSKTILFQVQTNNPPTETEIVNQSSATYQYVSIPTAPPVNRSANSNIVTTSL--QNA 3791 Query: 174 SILLASSTPTTFV--GDAVTFTLRVRNEGTRLMSGILTTLPVPEGAIFLPGSVISGGIYS 231 +I+ S TFV G +T+T ++N GT + + +PEG IF+ S+ + Sbjct: 3792 NIISVKSADVTFVSIGQIITYTNTLQNIGTIPANNTVFIDNIPEGTIFIEDSLSINNVIQ 3851 Query: 232 PDADPDKGIPLPPLDPGKTADISFQVRVVSVPA---LTAQAVVTYDADGDTDG------T 282 P A+P+ G+ L + P +T ISFQV++ ++P+ + + +Y+ D + Sbjct: 3852 PGANPENGVTLGTIQPNETVTISFQVQLTNIPSGNTVINLSDTSYEYQIDPSSPIIQRRS 3911 Query: 283 KSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTIRNSGKLAV-DAMLAGAIPSGTLF 341 SN V V + +S ++ G + Y + N+G + + +A+L AI +GT F Sbjct: 3912 LSNAVNTEVRTANVSAIKSANRSITRIGQIITYTVAVTNAGTVPITNALLIDAIAAGTTF 3971 Query: 342 VWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDL---LVSIPAEADILQMPAIQNQGS 398 V +S+ +DGI + +P GI LG I + +V +VSIP++ +I + I Sbjct: 3972 VPNSILVDGITRPNENPITGITLGIILPNNTIIVTFQVNVVSIPSQNNINNIAVIH---- 4027 Query: 399 VEYTFTLPDGRN--VRERVRSNTVTTLLFSPVISIEMTGEPPMVEPGGIAEFNIAVTNSG 456 EY PD + + E SN+ ++ + + I E+ + + N+G Sbjct: 4028 YEYQ---PDPSSPPISETTSSNSTNIQFIDAILIATKSANKVLANIDEIIEYTVLIQNNG 4084 Query: 457 NYPAE-VSVIQIIPQGCTLETGKVTISVHTVPESKYSGIVSLGVMDPGQTAQLSYLVRV 514 + + I G G V ++ +P + + S+ + GQ+ + + V V Sbjct: 4085 STTTNSIFFTDTIEDGTVFIPGSVIVNNTVLPAADPNIGFSIPNIASGQSTTIKFQVSV 4143 Score = 137 bits (344), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 110/405 (27%), Positives = 192/405 (47%), Gaps = 22/405 (5%) Query: 31 SNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGNAPALTT-LVDALPSGVSFV 89 SN V T + + VKSAD T S+G+ + YT +N G PA T +D +P G F+ Sbjct: 3781 SNIVTTSLQNANIISVKSADVTFVSIGQIITYTNTLQNIGTIPANNTVFIDNIPEGTIFI 3840 Query: 90 ANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTT 149 +S+ + V PG +P +G+ LG + P V I+FQV + ++P + N + Y + Sbjct: 3841 EDSLSINNVIQPGANPENGVTLGTIQPNETVTISFQVQLTNIPSGNTVINLSDTSYEYQI 3900 Query: 150 -PEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGIL 208 P ++ SN + + +S + +++ T +G +T+T+ V N GT ++ L Sbjct: 3901 DPSSPIIQRRSLSNAVNTEVRTANVSAIKSANRSITRIGQIITYTVAVTNAGTVPITNAL 3960 Query: 209 TTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVPA---L 265 + G F+P S++ GI P+ +P GI L + P T ++FQV VVS+P+ + Sbjct: 3961 LIDAIAAGTTFVPNSILVDGITRPNENPITGITLGIILPNNTIIVTFQVNVVSIPSQNNI 4020 Query: 266 TAQAVVTYDADGD------TDGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTI 319 AV+ Y+ D ++ T SN+ + I + L + +K A + + Y I Sbjct: 4021 NNIAVIHYEYQPDPSSPPISETTSSNSTNIQFIDAILIATKSANKVLANIDEIIEYTVLI 4080 Query: 320 RNSGKLAVDAM-LAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDLL 378 +N+G +++ I GT+F+ SV ++ P G + I +G + + Sbjct: 4081 QNNGSTTTNSIFFTDTIEDGTVFIPGSVIVNNTVLPAADPNIGFSIPNIASGQSTTIKFQ 4140 Query: 379 VSIPAEADILQMPAIQ---NQGSVEYTFTL-PDGRNVRERVRSNT 419 VS + +PA+ N ++ Y F PD +++ SNT Sbjct: 4141 VS------VTNLPAVNPTPNTANIVYDFIFNPDFAPIQKSTTSNT 4179 Score = 134 bits (336), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 133/523 (25%), Positives = 240/523 (45%), Gaps = 19/523 (3%) Query: 42 VLTLVKSADHTSASLGETLVYTLIARNEGNAPALTTL-VDALPSGVSFVANSVLRDGVPL 100 +LT K+++ + +G+ +VY++ N GN A + D +P+G SF NS +G+ + Sbjct: 2866 ILTAQKNSNAETVDIGQDIVYSVTITNSGNVSATNVIFTDLIPAGTSFEPNSFTLNGISI 2925 Query: 101 PGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYS-FTTPEGRHVEGEV 159 P + +G+ +G +AP V +AF + +PP + N+A + P V + Sbjct: 2926 PNANIITGVPIGDIAPNQSVIVAFHINANEIPPINPISNQASVSFQHIVNPANPPVSKNI 2985 Query: 160 FSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGILTTLPVPEGAIF 219 SN +T + + L+ + +GD +T+T + N G + ++ + P+P F Sbjct: 2986 TSNSVTTKIESAILNTIKIGDKAFATIGDTITYTTTITNTGNISANNVVFSDPIPTWTQF 3045 Query: 220 LPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVS-----VPALTAQAVVTYD 274 + GSV+ G P A G+ + + P + I FQV++VS P L V + Sbjct: 3046 VAGSVVVDGTPLPSASIISGVGINTITPNQIVTIVFQVQIVSNPTTFTPELQNLGFVNFQ 3105 Query: 275 AD-GDT----DGTKSNTVTVAVIQSGLSVSLKVDKYSAAP-GDRLGYRFTIRNSGKL-AV 327 + G++ G V V I S + ++K + A GD + Y I+NSG A Sbjct: 3106 YNVGNSLQAQPGNVETNVFVTSINSAILSAVKTANTAFANIGDTITYTVLIQNSGNTNAT 3165 Query: 328 DAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDLLVSIPAEADI 387 + + IP+GT FV +S ++G G P G+ +GT+ S+ V V + A Sbjct: 3166 NLNFSDLIPAGTTFVENSFSVNGSIIPGADPNNGVNIGTVSTNSSLTVTFQVMV---AST 3222 Query: 388 LQMPAIQNQGSVEYTFTL-PDGRNVRERVRSNTVTTLLFSPVISIEMTGEPPMVEPGGIA 446 I N GS+++TF + P V + SN +T + + ++ + +V G I Sbjct: 3223 PPSNPITNVGSIQFTFIVDPAAPPVTSTINSNGASTQINNATVTTVLEANRSIVSIGDII 3282 Query: 447 EFNIAVTNSGNYPAE-VSVIQIIPQGCTLETGKVTISVHTVPESKYSGIVSLGVMDPGQT 505 + +TN+GN+PA V +I +P G VT++ ++P + + + +G++ PG Sbjct: 3283 TYTATLTNTGNFPANSVLLINGVPVGAVFVPNSVTLNGMSLPNASPTLGIPVGIIAPGDF 3342 Query: 506 AQLSYLVRVHPGYMGSALQGSSTALYLYTIDGRRYSGEARSNS 548 A +++ A+ + Y Y +D + A S+S Sbjct: 3343 ATITFQFLASSIPPQGAIINQAITSYTYIVDPSQPPVTATSSS 3385 Score = 133 bits (334), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 144/502 (28%), Positives = 239/502 (47%), Gaps = 21/502 (4%) Query: 29 TYSNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGNAPALTTL-VDALPSGVS 87 T SN+V+T + + VKSAD A++G+T+ YT+ N GN + + D LP G + Sbjct: 2065 TTSNSVSTQINSGEIVAVKSADKNFATIGDTISYTITLNNPGNVTSQNIIFTDILPDGTT 2124 Query: 88 FVANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYS- 146 F++ ++ D +P SGI +G + P + I V+V ++P + N + + Sbjct: 2125 FISGTLTSDSGTQQIGNPASGIQIGNINPGSTATITINVLVTNIPSINPISNSSSIQFQH 2184 Query: 147 FTTPEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSG 206 P + V SN +T ++ + L+ ++ VGD +T+T + N G + Sbjct: 2185 IVDPSQPAITQTVSSNTVTTTINSAILTTTKSADKSIVSVGDTITYTTTITNTGNTAATN 2244 Query: 207 ILTTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVP--- 263 I T +P F+P SV G+ P A P G+ LP + PG+T ++FQV V+S+P Sbjct: 2245 ITFTSAIPASTTFIPNSVTVNGVQQPGAQPALGVNLPNIAPGETVTVTFQVNVISIPPSS 2304 Query: 264 ALTAQAVVTYDADGDTDG------TKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRF 317 ++ + Y D G T +N VT V+ + +++ VD+ GD + Y Sbjct: 2305 SIMDNDTILYSYTVDPSGAPITTSTSTNIVTNPVLDAMITMVKSVDQTLVTLGDTITYTT 2364 Query: 318 TIRNSGKL-AVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVD 376 ++NSG A + IP GT F+ DS+ IDGI Q G++P GI +G+I S+ + Sbjct: 2365 ILKNSGNTNATNITFTDLIPDGTTFITDSITIDGITQIGLNPNTGITIGSIAPNSS--IS 2422 Query: 377 LLVSIPAEADILQMPAIQNQGSVEYTFTL-PDGRNVRERVRSNTVTTLLFSPVISIEMTG 435 + + A + +Q P I N + YTF P+ V V SNT T + + I Sbjct: 2423 IAFQVTATSTPVQNP-IANSATASYTFIADPNAPIVSRNVTSNTTFTTINTATILSSKQV 2481 Query: 436 EPPMVEPGGIAEFNIAVTNSGNYPAE-VSVIQIIPQGCTLETGKVTISVHTVPES--KYS 492 + G + + +TN+GN A+ V +P G T T S++ +P+S + Sbjct: 2482 DKAFSHIGDTLTYTVTLTNNGNSSAQNVIFTDTVPSGTTFIAN--TFSINGIPQSGANPT 2539 Query: 493 GIVSLGVMDPGQTAQLSYLVRV 514 V++G + G T +S+ V V Sbjct: 2540 NGVNIGPITAGSTVNVSFRVNV 2561 Score = 132 bits (331), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 133/525 (25%), Positives = 229/525 (43%), Gaps = 19/525 (3%) Query: 47 KSADHTSASLGETLVYTLIARNEGNAPALT-TLVDALPSGVSFVANSVLRDGVPLPGVSP 105 KS D A++G+ L YT+I N G+ A T +D P G +F+ N+ L +GV P Sbjct: 1014 KSVDREFATVGDILTYTVILTNAGSVSADNPTFIDINPDGTTFIPNTFLINGVLQNNADP 1073 Query: 106 FSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFT-TPEGRHVEGEVFSNQI 164 G+LL ++ + +++QV V +LP N + YSF P + SN + Sbjct: 1074 NIGVLLPSIPASGLITVSYQVTVTALPAQNPTTNSSSTQYSFVLNPGDPPIIETSLSNTV 1133 Query: 165 TVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGILTTLPVPEGAIFLPGSV 224 + + + I+ VG +T+T+ + N G + ++ T +P G +P S+ Sbjct: 1134 STQINLANVVIVKEVDLTIADVGQPITYTISLANLGNTTANNVVVTDIIPPGTTIVPNSI 1193 Query: 225 ISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVPA---LTAQAVVTYDADGDTD- 280 GG ADP G+ + + G I FQ+ +P+ + A + Y+ D + Sbjct: 1194 FIGGALQLGADPSTGLQVGSIPAGGFTTIVFQISANGLPSPNPIQNSASLQYNFIADPNL 1253 Query: 281 -----GTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTIRNSGKL-AVDAMLAGA 334 SN VT + + + + SA GD + Y + N+G + A + Sbjct: 1254 PVVVKNATSNIVTTQINTANIVATKLTSTNSADVGDVILYATILTNNGNIPASNVTFTDI 1313 Query: 335 IPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDLLVSIPAEADILQMPAIQ 394 IP+GTLF+ ++V I+ +P +P GI +GTI A S+ V V +P I + I Sbjct: 1314 IPAGTLFIPNTVTINNVPIANANPANGIFIGTIGANSSRTVAFQVLVPT---IPAVNPIT 1370 Query: 395 NQGSVEYTFTL-PDGRNVRERVRSNTVTTLLFSPVISIEMTGEPPMVEPGGIAEFNIAVT 453 NQ + +T P V + V SNTV T + + I+ + + I + +T Sbjct: 1371 NQSGTTFQYTYDPSKPAVMQMVASNTVQTTINNASIAATKSADKQFANVNDIITYTTTLT 1430 Query: 454 NSGNYPA-EVSVIQIIPQGCTLETGKVTISVHTVPESKYSGIVSLGVMDPGQTAQLSYLV 512 N+GN A + IP G + VT++ T+P + +++ ++P +S+ + Sbjct: 1431 NNGNTLASNIVFTDAIPSGTSFIPNSVTVNGTTLPNVNPANGIAIDPINPNANTTISFQI 1490 Query: 513 RVHPGYMGSALQGSSTALYLYTIDGRR--YSGEARSNSYKLMIEE 555 +V+ + + S Y Y ++ S A SN I Sbjct: 1491 KVNSIPSPNPIPNQSNTTYQYIVNPNLPPASANALSNVITTQINN 1535 Score = 127 bits (320), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 103/366 (28%), Positives = 171/366 (46%), Gaps = 31/366 (8%) Query: 47 KSADHTSASLGETLVYTLIARNEGNAPALTTLV-DALPSGVSFVANSVLRDGVPLPGVSP 105 K D A++G+TL YT+ GN A ++ D +P G +F+ NSV+ +G LPGV+P Sbjct: 4450 KDVDLAFATVGDTLTYTITLNQTGNVSANDVIIQDIIPQGTTFIENSVIVNGETLPGVNP 4509 Query: 106 FSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSF-TTPEG--------RHVE 156 SGI +G + +FQV V S+P EL N+A +++ P + Sbjct: 4510 VSGIPIGTIIVGGNAIASFQVTVTSIPTPNELNNKAITTFNYIVNPNNLPVTNTTTTNTV 4569 Query: 157 GEVFSNQITVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGILTTLPVPEG 216 N V+ + + L S T +T+T+ + N G + +L VP Sbjct: 4570 TTTVQNDNVVATKSVNATNALPSQT--------LTYTITITNSGNVTIEDLLAIDTVPVD 4621 Query: 217 AIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVS---VPALTAQAVVTY 273 F+ SV GI P+A+P+ GI L L P ++ I+FQ+ + S +PA+ A V+Y Sbjct: 4622 TTFVTSSVTINGINQPNANPENGITLGNLAPNESVIITFQITISSSTLLPAINNDASVSY 4681 Query: 274 DADGD------TDGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTIRNSGKL-A 326 D T ++N VT ++ + ++ +K GD + + + N + Sbjct: 4682 TVIIDPNEPPITMTKQTNVVTTTIVDPMVGIAKIANKSITITGDIITFTLDVFNHSPIPT 4741 Query: 327 VDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVD---LLVSIPA 383 V+ + IP+GT F+ +SV I+G + P GI +G + A A + L+ SIP+ Sbjct: 4742 VNTSVLDMIPAGTTFIENSVTINGTQIPNIRPDTGINIGALPADGVATITFKVLVTSIPS 4801 Query: 384 EADILQ 389 + I+ Sbjct: 4802 NSTIIN 4807 Score = 127 bits (319), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 119/420 (28%), Positives = 189/420 (45%), Gaps = 18/420 (4%) Query: 31 SNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGNAPALT-TLVDALPSGVSFV 89 SN V+T + +L++ K+ + A +G+T YT N GN A D LPSG++F+ Sbjct: 2591 SNPVSTQIREAILSMTKNESLSFADVGQTAFYTTSITNVGNTDATNIVFTDVLPSGLTFI 2650 Query: 90 ANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTT 149 N++ DG+ P P +G+LL A+ P I FQV V S+PP N A Y FT Sbjct: 2651 PNTLTVDGILQPNADPNTGVLLAALPPNEIYSIVFQVTVNSIPPINPAPNTASTTYEFTV 2710 Query: 150 PEGRHVEGEVFSNQITVSLLAYKLSILLASSTPTTF--VGDAVTFTLRVRNEGTRLMSGI 207 G S+ T+ L +I+ + TF VG+ +TFTL + N G + + Sbjct: 2711 DPGNPPVSNTASSNTTL-LQINNANIISTKTANLTFADVGNTITFTLNLPNTGNVAATDV 2769 Query: 208 LTTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVPALT- 266 + F+P S G P+AD G+ + ++ G TA ++FQ V ++P L Sbjct: 2770 TIIDILDSNLSFIPNSFTVNGQTIPNADLSTGVNIGSINGGNTAIVTFQATVTTLPTLNP 2829 Query: 267 ----AQAVVTYDADGDTDGTKSNTVTVAVIQSGLSVSLKVDKYSAAP----GDRLGYRFT 318 A Y D ++ + S L K S A G + Y T Sbjct: 2830 ISNFASTTYHYVVDPSLPPITTSNQSNTTTTQINSAILTAQKNSNAETVDIGQDIVYSVT 2889 Query: 319 IRNSGKL-AVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDL 377 I NSG + A + + IP+GT F +S ++GI + G+P+G I + +V Sbjct: 2890 ITNSGNVSATNVIFTDLIPAGTSFEPNSFTLNGISIPNANIITGVPIGDIAPNQSVIVAF 2949 Query: 378 LVSIPAEADILQMPAIQNQGSVEYTFTL-PDGRNVRERVRSNTVTTLLFSPVISIEMTGE 436 ++ +I + I NQ SV + + P V + + SN+VTT + S +++ G+ Sbjct: 2950 HIN---ANEIPPINPISNQASVSFQHIVNPANPPVSKNITSNSVTTKIESAILNTIKIGD 3006 Score = 124 bits (312), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 113/428 (26%), Positives = 191/428 (44%), Gaps = 17/428 (3%) Query: 47 KSADHTSASLGETLVYTLIARNEGNAPALTTL-VDALPSGVSFVANSVLRDGVPLPGVSP 105 KS + +GETL Y++ N GN A + D +PSG +F+ SV +GV G +P Sbjct: 488 KSVNKLFTDIGETLTYSIALANIGNIAATNVIYTDPIPSGTTFIPGSVTVNGVTQGGANP 547 Query: 106 FSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFT-TPEGRHVEGEVFSNQI 164 +GI +G++A + I+FQV V S+P + + N Y + P V G +N + Sbjct: 548 ANGISIGSIAANSTTTISFQVFVPSIPQTNPILNSGTTTYQYIPVPNQPAVSGTDTTNIV 607 Query: 165 TVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGILTTLPVPEGAIFLPGSV 224 + + +++ A +GD +T+T+ G + ++ T +P G F+ S+ Sbjct: 608 STQVNNATVTMTKAVDKNYADIGDTLTYTVAFTGTGNTNANNVIFTDVIPTGTTFVLNSL 667 Query: 225 ISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVPALTA---------QAVVTYDA 275 G A+P G+ + + G T +SFQV V ++PA A Q V Sbjct: 668 TIDGSTQVGANPANGVNIGSIPTGTTKSVSFQVVVNTIPASNAVSNGSSASYQYTVNPSQ 727 Query: 276 DGDTDGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTIRNSGKLAVDAM-LAGA 334 SN VT + + L+++ +K A G+ + Y I NSG A + + L Sbjct: 728 SPIMKNISSNVVTTQINNANLTLTKSTNKQFATIGETISYTILITNSGNTAANNVQLTDP 787 Query: 335 IPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVDLLVSIPAEADILQMPAIQ 394 +P+GT+ SV ++G+ Q V +P+GTI G+ + V++ +I I Sbjct: 788 LPNGTILTLGSVTLNGVLQN-VDSLVALPIGTIPGGATFTLSFQVTV---INITAQNPII 843 Query: 395 NQGSVEYTFTL-PDGRNVRERVRSNTVTTLLFSPVISIEMTGEPPMVEPGGIAEFNIAVT 453 N Y +T+ P + SN+VT+ + + + E G + + A+T Sbjct: 844 NNAFSSYIYTVNPSLPPTSKTANSNSVTSTIRLANLHANKSVSQTFAEVGDVLTYTFALT 903 Query: 454 NSGNYPAE 461 N GN A Sbjct: 904 NDGNVTAN 911 Score = 119 bits (298), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 131/464 (28%), Positives = 215/464 (46%), Gaps = 31/464 (6%) Query: 31 SNTVNTPVVGPVLTLVKSADHTSASLGETLVYTLIARNEGNAPALTT-LVDALPSGVSFV 89 SN V T + LTL KS + A++GET+ YT++ N GN A L D LP+G Sbjct: 736 SNVVTTQINNANLTLTKSTNKQFATIGETISYTILITNSGNTAANNVQLTDPLPNGTILT 795 Query: 90 ANSVLRDGVPLPGVSPFSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFT- 148 SV +GV L V + +G + ++FQV V+++ + N A + Y +T Sbjct: 796 LGSVTLNGV-LQNVDSLVALPIGTIPGGATFTLSFQVTVINITAQNPIINNAFSSYIYTV 854 Query: 149 TPEGRHVEGEVFSNQITVSLLAYKLSILLAS-STPTTF--VGDAVTFTLRVRNEGTRLMS 205 P SN +T ++ +L+ L A+ S TF VGD +T+T + N+G + Sbjct: 855 NPSLPPTSKTANSNSVTSTI---RLANLHANKSVSQTFAEVGDVLTYTFALTNDGNVTAN 911 Query: 206 GILTTLPVPEGAIFLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVPA- 264 +L + + G F+P SVI G+ P A P I + ++ T SFQ+ + S+P Sbjct: 912 NVLLSDSIANGTSFVPNSVIVNGVTQPGATP-ASINIGSINANTTITASFQILITSIPNP 970 Query: 265 --LTAQAVVTYDADGDTDGTKSNTVT------VAVIQSGLSVSLKVDKYSAAPGDRLGYR 316 + A ++Y+ D + + +T T + V + + + VD+ A GD L Y Sbjct: 971 NPILNSASISYNFIVDPNASPVSTNTTTNTTFIQVNDANVISAKSVDREFATVGDILTYT 1030 Query: 317 FTIRNSGKLAVDA-MLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVV 375 + N+G ++ D P GT F+ ++ I+G+ Q P G+ L +I A Sbjct: 1031 VILTNAGSVSADNPTFIDINPDGTTFIPNTFLINGVLQNNADPNIGVLLPSIPASG---- 1086 Query: 376 DLLVSIPAEADILQMPA---IQNQGSVEYTFTL-PDGRNVRERVRSNTVTTLLFSPVISI 431 L+++ + + +PA N S +Y+F L P + E SNTV+T + + I Sbjct: 1087 --LITVSYQVTVTALPAQNPTTNSSSTQYSFVLNPGDPPIIETSLSNTVSTQINLANVVI 1144 Query: 432 EMTGEPPMVEPGGIAEFNIAVTNSGNYPA-EVSVIQIIPQGCTL 474 + + + G + I++ N GN A V V IIP G T+ Sbjct: 1145 VKEVDLTIADVGQPITYTISLANLGNTTANNVVVTDIIPPGTTI 1188 Score = 105 bits (261), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 146/523 (27%), Positives = 244/523 (46%), Gaps = 42/523 (8%) Query: 47 KSADHTSASLGETLVYTLIARNEGNAPALT-TLVDALPSGVSFVANSVLRDGVPLPGVSP 105 K+A A++G+T+ YT N GN A T +D LP +SFV +SV + P G P Sbjct: 1806 KTASSAFAAVGDTITYTTTLTNSGNTTANTPVFIDILPPELSFVPDSVQINTTPQLGFRP 1865 Query: 106 FSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYSFTT-PEGRHVEGEVFSNQI 164 +G+ L + I+FQ IV S+P S N++ YS P V SN + Sbjct: 1866 DNGVPLDPIPVGGTTTISFQAIVGSIPDSNPTMNQSSTTYSIIIDPTEPPVTETATSNPV 1925 Query: 165 TVSLLAYKLSILLASSTPTTFVGDA------VTFTLRVRNEGTRLMSGILTTLPVPEGAI 218 L+ +I+ A+ + D +T+T+ + N G + I+ T P+P + Sbjct: 1926 ---LVQINEAIIQATKSVDRIFSDVAPGNSFLTYTVLLENIGNTTATNIIFTDPIPNNTV 1982 Query: 219 FLPGSVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVP--------------- 263 F+ SV GG+ P +P GIP+ + G +++F+V+VVS+P Sbjct: 1983 FIEDSVRVGGVLLPGVNPANGIPIGDIIAGDFINVTFRVQVVSIPNPIFTIGPGGPNSPV 2042 Query: 264 ----ALTAQAVVTYDADGDTDGTKSNTVTVAVIQSGLSVSLK-VDKYSAAPGDRLGYRFT 318 ++ Q + + + T SN+V+ I SG V++K DK A GD + Y T Sbjct: 2043 VNGASINYQFMTGPNLPLVSQSTTSNSVSTQ-INSGEIVAVKSADKNFATIGDTISYTIT 2101 Query: 319 IRNSGKL-AVDAMLAGAIPSGTLFVWDSVHIDGIPQRGVHPGEGIPLGTIRAGSAAVVD- 376 + N G + + + + +P GT F+ ++ D Q+ +P GI +G I GS A + Sbjct: 2102 LNNPGNVTSQNIIFTDILPDGTTFISGTLTSDSGTQQIGNPASGIQIGNINPGSTATITI 2161 Query: 377 --LLVSIPAEADILQMPAIQNQGSVEYTFTLPDGRNVRERVRSNTVTTLLFSPVISIEMT 434 L+ +IP+ I +IQ Q V+ P + + V SNTVTT + S +++ + Sbjct: 2162 NVLVTNIPSINPISNSSSIQFQHIVD-----PSQPAITQTVSSNTVTTTINSAILTTTKS 2216 Query: 435 GEPPMVEPGGIAEFNIAVTNSGNYPA-EVSVIQIIPQGCTLETGKVTISVHTVPESKYSG 493 + +V G + +TN+GN A ++ IP T VT++ P ++ + Sbjct: 2217 ADKSIVSVGDTITYTTTITNTGNTAATNITFTSAIPASTTFIPNSVTVNGVQQPGAQPAL 2276 Query: 494 IVSLGVMDPGQTAQLSYLVRVHPGYMGSALQGSSTALYLYTID 536 V+L + PG+T +++ V V S++ + T LY YT+D Sbjct: 2277 GVNLPNIAPGETVTVTFQVNVISIPPSSSIMDNDTILYSYTVD 2319 Score = 90.5 bits (223), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 72/270 (26%), Positives = 135/270 (50%), Gaps = 8/270 (2%) Query: 2 IRDSRLQPVVSNQSMVLYSSAAGAD-----VITYSNTVNTPVVGPVLTLVKSADHTSASL 56 I S L P ++N + V Y+ + + +N V T +V P++ + K A+ + Sbjct: 4664 ISSSTLLPAINNDASVSYTVIIDPNEPPITMTKQTNVVTTTIVDPMVGIAKIANKSITIT 4723 Query: 57 GETLVYTLIARNEGNAPAL-TTLVDALPSGVSFVANSVLRDGVPLPGVSPFSGILLGAVA 115 G+ + +TL N P + T+++D +P+G +F+ NSV +G +P + P +GI +GA+ Sbjct: 4724 GDIITFTLDVFNHSPIPTVNTSVLDMIPAGTTFIENSVTINGTQIPNIRPDTGINIGALP 4783 Query: 116 PQTEVRIAFQVIVVSLPPSLELGNRARAVYSFT-TPEGRHVEGEVFSNQITVSLLAYKLS 174 I F+V+V S+P + + N A +F TP+ + V SN + + + + Sbjct: 4784 ADGVATITFKVLVTSIPSNSTIINSATVTAAFQLTPQDPIITFIVNSNIVRIPVQFITAT 4843 Query: 175 ILLASSTPTTFVGDAVTFTLRVRNEGTRLMSGILTTLPVPEGAIFLPGSVISGGIYSPDA 234 +L +S + ++ +T+ + N ++ I +P G F+ G+V G SP A Sbjct: 4844 VLKNASVSSAYLNQYFDYTVHITNTSEFSITNISLQDTIPAGLRFMNGTVFINGERSPLA 4903 Query: 235 DPDKGIPLPP-LDPGKTADISFQVRVVSVP 263 +P+ G + L+P +T + F V+V+S P Sbjct: 4904 NPNIGFLVATNLEPNETIIVLFTVQVISPP 4933 Score = 89.0 bits (219), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 87/325 (26%), Positives = 146/325 (44%), Gaps = 30/325 (9%) Query: 47 KSADHTSASLGETLVYTLIARNEGNAPALTTL-VDALPSGVSFVANSVLRDGVPLPGVSP 105 KS + T+A +TL YT+ N GN L +D +P +FV +SV +G+ P +P Sbjct: 4582 KSVNATNALPSQTLTYTITITNSGNVTIEDLLAIDTVPVDTTFVTSSVTINGINQPNANP 4641 Query: 106 FSGILLGAVAPQTEVRIAFQVIVVSLPPSLELGNRARAVYS-FTTPEGRHVEGEVFSNQI 164 +GI LG +AP V I FQ+ + S + N A Y+ P + +N + Sbjct: 4642 ENGITLGNLAPNESVIITFQITISSSTLLPAINNDASVSYTVIIDPNEPPITMTKQTNVV 4701 Query: 165 TVSLLAYKLSILLASSTPTTFVGDAVTFTLRVRNEGT--RLMSGILTTLPVPEGAIFLPG 222 T +++ + I ++ T GD +TFTL V N + + +L +P G F+ Sbjct: 4702 TTTIVDPMVGIAKIANKSITITGDIITFTLDVFNHSPIPTVNTSVLDM--IPAGTTFIEN 4759 Query: 223 SVISGGIYSPDADPDKGIPLPPLDPGKTADISFQVRVVSVPA---------------LTA 267 SV G P+ PD GI + L A I+F+V V S+P+ LT Sbjct: 4760 SVTINGTQIPNIRPDTGINIGALPADGVATITFKVLVTSIPSNSTIINSATVTAAFQLTP 4819 Query: 268 Q-AVVTYDADGDTDGTKSNTVTVAVIQSGLSVSLKVDKYSAAPGDRLGYRFTIRNSGKLA 326 Q ++T+ + + +T V+++ S +++Y Y I N+ + + Sbjct: 4820 QDPIITFIVNSNIVRIPVQFITATVLKNASVSSAYLNQY-------FDYTVHITNTSEFS 4872 Query: 327 VDAM-LAGAIPSGTLFVWDSVHIDG 350 + + L IP+G F+ +V I+G Sbjct: 4873 ITNISLQDTIPAGLRFMNGTVFING 4897 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.315 0.133 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,296,250,212 Number of extensions: 144436863 Number of successful extensions: 386468 Number of sequences better than 1.0e-05: 283 Number of HSP's gapped: 366199 Number of HSP's successfully gapped: 3048 Length of query: 558 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 417 Effective length of database: 1,732,333,088 Effective search space: 722382897696 Effective search space used: 722382897696 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 134 (56.2 bits)