BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0298.0002.p (799 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K5V3.1 B3K5V3_9BACI Polyprenyl synthetase 1121 0.0 Q2B3T0.1 Q2B3T0_9BACI Geranyltranstransferase (Farnesyl-diphosph... 886 0.0 A0LI56.1 A0LI56_SYNFM Farnesyl-diphosphate synthase EC=2.5.1.10 164 3e-38 A3DDN7.1 A3DDN7_CLOTH Farnesyl-diphosphate synthase EC=2.5.1.10 161 3e-37 B4BCZ4.1 B4BCZ4_CLOTM Polyprenyl synthetase 161 3e-37 >B3K5V3.1 B3K5V3_9BACI Polyprenyl synthetase Length = 794 Score = 1121 bits (2900), Expect = 0.0, Method: Compositional matrix adjust. Identities = 540/797 (67%), Positives = 638/797 (80%), Gaps = 3/797 (0%) Query: 3 MNENFTEQGDTVYRLAEHKAAQYFAALNMQVMDKTYVPILTKDIQSWKKNHIRQWSWLSF 62 MN +T+ DT YR AE KAAQYFA+L++QV DK+YVPILT+DI WK+ H+++ SWLS Sbjct: 1 MNVAYTDYADTGYRQAEQKAAQYFASLHVQVKDKSYVPILTEDILIWKRKHVQRQSWLSS 60 Query: 63 FTRRKRAGDTRDDQKYLEWLNYTGRLDNYLDRSVSYIYMRDLGKALDDPRTKTRIQRVVT 122 K+ D RD +Y+ WLNYTG LD+YLDRS+SYIYMRDLG ALD P TK RI+RVV Sbjct: 61 ILPAKKKPDNRDYHRYIGWLNYTGELDDYLDRSISYIYMRDLGMALDSPDTKERIRRVVA 120 Query: 123 DLKRHLMHSGANEQEDQTGLTGLSSIAGFYRWAQKEGIEAAAIWVIDKLKAVSSHIPEEM 182 + ++ L+ S ++ D S+AG YRWAQKEGIE A IWVI+KLK V+SHIP++M Sbjct: 121 NTRKLLVRSNGAKEGDTPDFM---SLAGLYRWAQKEGIETAVIWVINKLKHVASHIPDKM 177 Query: 183 DAEQAERKLIKIIVGVILHVVEEMDEQTTPAERTRRLDEAIRIGYSYGLTYPFIDDLLDS 242 DAEQA+RKLIKIIVGV++HV+E+++ +T+PAER+ RLD+AIR+GYSYGLTYPFIDDLLDS Sbjct: 178 DAEQAQRKLIKIIVGVVMHVMEDLNGETSPAERSARLDDAIRLGYSYGLTYPFIDDLLDS 237 Query: 243 RVLTAPEKEQYSAMIRTALLTGKVPELSEWPGVHMEIIQYVHTELRTAFEYIQSLQKPET 302 VL A EKEQYS MIR ALLTGKVPEL +W G +ME++ +VH ELR AFEYIQ Q+PET Sbjct: 238 GVLNAQEKEQYSHMIRQALLTGKVPELGQWSGKNMELVHFVHQELRDAFEYIQGRQRPET 297 Query: 303 GATFFEQSYVFFHSQDIDRNKEPANADYTNEELYIPXXXXXXXXXXXXXXXXXAAEDKGF 362 TFFEQS VFFHSQ IDR K+ AN DYTNEELY+P AA D GF Sbjct: 298 QQTFFEQSNVFFHSQHIDRIKDLANPDYTNEELYLPIILKSSSSRLIVRSVISAAADGGF 357 Query: 363 EERTFFYGIYNQLXXXXXXXXXXXXXGAVTPYTYYLKYRKQCPDLINPYELYWTVISHLI 422 E+RTF+YGIYNQL GAVTPYTYYLKYR Q DLINP+ELYW VISHLI Sbjct: 358 EDRTFYYGIYNQLADDFADMFQDLNDGAVTPYTYYLKYRGQRQDLINPFELYWAVISHLI 417 Query: 423 HNVYHSDAKTLEVIMDRAINGLKRCKERVGTERYNEIMEIFASGNPEFNRLIQQMVRKAD 482 HNVYHSDAKT EV++DRAINGLKRCKERVGTE+YNEIM+IFASGNPEFNRLIQ MV KAD Sbjct: 418 HNVYHSDAKTREVMLDRAINGLKRCKERVGTEKYNEIMDIFASGNPEFNRLIQHMVSKAD 477 Query: 483 DVDFFDKLLRDQINTQLQNDRKEKEKFQTTVRTVREQINGLLKIPRPDGIPPMKESLIEA 542 VDF DKLLRDQ+ T L+N+RKEK+ F T ++VR++IN L+I + GIPPMKESLI+A Sbjct: 478 QVDFLDKLLRDQMVTVLRNERKEKDYFIDTFKSVRDEINQHLQIDKTPGIPPMKESLIDA 537 Query: 543 ANYSLTGDGKRIRPILTWVLGVEVYGLQAAAIEPLLRSLEFMHTASLIFDDLPSQDNAST 602 ANYSL GDGKR+RPILTWV+ V+ YGLQA AI PLLRSLE+MHTASLIFDDLPSQDNAST Sbjct: 538 ANYSLEGDGKRLRPILTWVMAVKEYGLQATAIVPLLRSLEYMHTASLIFDDLPSQDNAST 597 Query: 603 RRGRPTLHQVHNSATAELTGLYLIQKAIQEQASLRAFDPAAVLALMHYSAEKAEDMCMGQ 662 RRGRPTLHQVH+SATAE+TGL+LIQKAI+EQ+SL FDP VL L+ YS+++A DMC GQ Sbjct: 598 RRGRPTLHQVHDSATAEITGLFLIQKAIEEQSSLEGFDPKTVLKLIRYSSQRAGDMCSGQ 657 Query: 663 AMDLHSKGKAMTLEQLNMMCFYKTGLAFEASLVMPAILAGVPQAEINALKKYAYHAGIAF 722 AMDL+SKGKA++LEQLN +C+YKTG+AFEASLVMPAILA V + EI LKK+AYHAGIAF Sbjct: 658 AMDLNSKGKALSLEQLNTVCYYKTGIAFEASLVMPAILAQVKETEIAILKKFAYHAGIAF 717 Query: 723 QIKDDLLDLEGDQQVLGKNTRMDAENNNSTFVSVLGAEAARFEMWDHYCHAVEALNAVPR 782 QI+DDLLD++G+ + LGK DAENN STFVS+LG E A EMWDHYC A+EAL +PR Sbjct: 718 QIQDDLLDVQGNVEQLGKPGGQDAENNTSTFVSILGQEGASREMWDHYCQAMEALQEMPR 777 Query: 783 KIAFLNHLLDYIINRNR 799 AFL HLL+Y++NR R Sbjct: 778 NTAFLKHLLNYMVNRER 794 >Q2B3T0.1 Q2B3T0_9BACI Geranyltranstransferase (Farnesyl-diphosphate synthase) Length = 788 Score = 886 bits (2289), Expect = 0.0, Method: Compositional matrix adjust. Identities = 428/788 (54%), Positives = 554/788 (70%), Gaps = 9/788 (1%) Query: 12 DTVYRLAEHKAAQYFAALNMQVMDKTYVPILTKDIQSWKKNHIRQWSWLSFFTRRKRAGD 71 + YR AE KAA YF AL Q +K+++P+L +D SWKKNH + S+L FF+R+ R D Sbjct: 10 EACYREAEKKAAAYFQALFAQASEKSFIPVLERDFHSWKKNHRQTSSFLPFFSRKNRKPD 69 Query: 72 TRDDQKYLEWLNYTGRLDNYLDRSVSYIYMRDLGKALDDPRTKTRIQRVVTDLKRHLMHS 131 ++ Y++WL Y G+LD+YLDRS+SY+YMRDLGK+LDD TK I R V LK L Sbjct: 70 SKAYHSYIKWLEYRGKLDDYLDRSISYLYMRDLGKSLDDRDTKESIGRAVESLKERLTAP 129 Query: 132 GANEQEDQTGLTGLSSIAGFYRWAQKEGIEAAAIWVIDKLKAVSSHIPEEMDAEQAERKL 191 E E +AG YRWA+KEGI++A IW+++KL+ + +IPE MDA A+RKL Sbjct: 130 KQQEAE-------YFGMAGLYRWAEKEGIQSAVIWLMEKLQQTARNIPEGMDAAHAQRKL 182 Query: 192 IKIIVGVILHVVEEMDEQTTPAERTRRLDEAIRIGYSYGLTYPFIDDLLDSRVLTAPEKE 251 IKII GV++H E M E ER RRL+ AIR+GYSYGLTYPFIDDLLDSRVL+ EK+ Sbjct: 183 IKIIAGVLMHETEAMKEGIEAGERKRRLERAIRLGYSYGLTYPFIDDLLDSRVLSEDEKK 242 Query: 252 QYSAMIRTALLTGKVPELSEWPGVHMEIIQYVHTELRTAFEYIQSLQKPETGATFFEQSY 311 Q+S +I T L TG VP L W + +I YVH ELR AF YI++ Q PET A+F EQ+Y Sbjct: 243 QFSELICTTLTTGSVPPLGRWQRAILPLITYVHNELREAFHYIKAQQTPETLASFLEQAY 302 Query: 312 VFFHSQDIDRNKEPANADYTNEELYIPXXXXXXXXXXXXXXXXXAAEDKGFEERTFFYGI 371 VFF SQ++DR K+ ++ YTNEELYIP + +D GF+ RTF+YGI Sbjct: 303 VFFQSQEVDRQKDLNDSSYTNEELYIPVILKSSSSRLIVRSVLNSGKDDGFDSRTFYYGI 362 Query: 372 YNQLXXXXXXXXXXXXXGAVTPYTYYLKYRKQCPDLINPYELYWTVISHLIHNVYHSDAK 431 YNQL GAVTPYTYYL + + DL+NP+E+YWTVI HLIH+VY S+ K Sbjct: 363 YNQLADDFADLFADLEDGAVTPYTYYLTHYRARHDLLNPFEVYWTVIVHLIHDVYGSNPK 422 Query: 432 TLEVIMDRAINGLKRCKERVGTERYNEIMEIFASGNPEFNRLIQQMVRKADDVDFFDKLL 491 EVI+DRAINGLKR KER+G E+Y E+ME+FA G+PEF+RLIQQM KA DVDFFDKLL Sbjct: 423 AREVILDRAINGLKRSKERLGKEKYREVMELFAPGSPEFSRLIQQMAAKAADVDFFDKLL 482 Query: 492 RDQINTQLQNDRKEKEKFQTTVRTVREQINGLLKIPRPDGIPPMKESLIEAANYSLTGDG 551 RD + LQ +R +E F+ V V+++IN +L+I D + M E + EAANYSL G Sbjct: 483 RDHMLDSLQKERLGQEDFRYKVEEVQKRINNVLRIEDKDLL--MGEPVREAANYSLAAGG 540 Query: 552 KRIRPILTWVLGVEVYGLQAAAIEPLLRSLEFMHTASLIFDDLPSQDNASTRRGRPTLHQ 611 KR+RP++ W +GVE YG++ A+ PLLRSLE+MHTASLIFDDLP+QDNA +RRG+ +H+ Sbjct: 541 KRLRPVIAWFVGVEAYGMEETALMPLLRSLEYMHTASLIFDDLPAQDNAPSRRGKAAVHE 600 Query: 612 VHNSATAELTGLYLIQKAIQEQASLRAFDPAAVLALMHYSAEKAEDMCMGQAMDLHSKGK 671 V+ +A AEL+GLYL QKA+++QASL + P AVL L+ Y+A +MC GQAMDL +KGK Sbjct: 601 VYGTAAAELSGLYLTQKAMEDQASLTSSTPDAVLELIRYTARSTAEMCRGQAMDLEAKGK 660 Query: 672 AMTLEQLNMMCFYKTGLAFEASLVMPAILAGVPQAEINALKKYAYHAGIAFQIKDDLLDL 731 A+T +L+ +CFYKTG+AFEAS++MPAILAG Q EI+ LKK+A HAGIAFQI+DDLLD+ Sbjct: 661 ALTAGELDALCFYKTGIAFEASIIMPAILAGAEQDEIDVLKKFARHAGIAFQIRDDLLDV 720 Query: 732 EGDQQVLGKNTRMDAENNNSTFVSVLGAEAARFEMWDHYCHAVEALNAVPRKIAFLNHLL 791 EGD +LGK D N T+VS LG + A+ MW+HYC A E L + + AFL +LL Sbjct: 721 EGDPMLLGKPVGTDRRNQKETYVSALGKDGAKRSMWEHYCSAAELLQELRAEFAFLGYLL 780 Query: 792 DYIINRNR 799 DY+++R + Sbjct: 781 DYMVHREK 788 >A0LI56.1 A0LI56_SYNFM Farnesyl-diphosphate synthase EC=2.5.1.10 Length = 296 Score = 164 bits (416), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 103/275 (37%), Positives = 150/275 (54%), Gaps = 7/275 (2%) Query: 527 PRPDGIPPMKESLIEAANYSLTGDGKRIRPILTWVLGVEVYGLQAAAIEPLLRSLEFMHT 586 P P G +++S++EAA YSL GKR+RPIL EV G A P +LE +HT Sbjct: 25 PVPSG---LEKSVLEAARYSLFAGGKRLRPILCLA-AAEVAGGSREAAMPAACALEMIHT 80 Query: 587 ASLIFDDLPSQDNASTRRGRPTLHQVHNSATAELTGLYLIQKAIQEQASLRA-FDPAAVL 645 SLI DDLP+ DN RRG+PT H+V A A L G L+ +A + + P +L Sbjct: 81 YSLIHDDLPAMDNDDFRRGKPTNHKVFGEAIAVLAGDALLTEAFDFVSKMDGDIPPRKIL 140 Query: 646 ALMH--YSAEKAEDMCMGQAMDLHSKGKAMTLEQLNMMCFYKTGLAFEASLVMPAILAGV 703 A++ A M GQ +DL + + + L + M +KTG ASL + A+L G Sbjct: 141 AVVATLVRASGYRGMIGGQVIDLECENRTVDLATVEYMHIHKTGALLSASLEVGALLGGG 200 Query: 704 PQAEINALKKYAYHAGIAFQIKDDLLDLEGDQQVLGKNTRMDAENNNSTFVSVLGAEAAR 763 A++++LK+Y +H G+AFQI DDLLD+EGD + +GK DA N T+ ++LG +R Sbjct: 201 SDAQVSSLKRYGHHLGLAFQITDDLLDVEGDAREMGKKPGSDAAKNKKTYPALLGITRSR 260 Query: 764 FEMWDHYCHAVEALNAVPRKIAFLNHLLDYIINRN 798 +H A++AL A + L + Y++ R Sbjct: 261 EAAREHVDAALQALAAFDDRAEPLRAIARYLLVRK 295 >A3DDN7.1 A3DDN7_CLOTH Farnesyl-diphosphate synthase EC=2.5.1.10 Length = 295 Score = 161 bits (407), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 104/266 (39%), Positives = 147/266 (55%), Gaps = 5/266 (1%) Query: 536 KESLIEAANYSLTGDGKRIRPILTWVLGVEVYGLQAAAIEPLLRSLEFMHTASLIFDDLP 595 ++SL A YSL GKR+RP+L+ + ++ G + P ++E +HT SLI DDLP Sbjct: 29 EKSLYSAMRYSLMAGGKRLRPVLSLAV-CDMLGGSVEQVLPFACAVEMIHTYSLIHDDLP 87 Query: 596 SQDNASTRRGRPTLHQVHNSATAELTGLYLIQKA--IQEQASLRAFD--PAAVLALMHYS 651 + DN RRGRPT H+V+ A A L G L+ A I + ++ D + A + Sbjct: 88 AMDNDDFRRGRPTNHKVYGEALAILAGDGLLNLAFEIMLENIIKNGDMERKSKAAAVIAK 147 Query: 652 AEKAEDMCMGQAMDLHSKGKAMTLEQLNMMCFYKTGLAFEASLVMPAILAGVPQAEINAL 711 A M GQ +DL S+GK + E LN M KTG +A +V AIL G +I L Sbjct: 148 AAGMNGMIAGQVIDLESEGKQVDNEILNRMHRLKTGALIKAPVVSAAILCGADADDIQKL 207 Query: 712 KKYAYHAGIAFQIKDDLLDLEGDQQVLGKNTRMDAENNNSTFVSVLGAEAARFEMWDHYC 771 ++A + G+AFQIKDD+LD+EG + LGK DA+NN ST+V+V G E ++ + D Sbjct: 208 DEFAENLGLAFQIKDDILDVEGSSEKLGKKVGSDADNNKSTYVTVYGLEKSKEILSDVTK 267 Query: 772 HAVEALNAVPRKIAFLNHLLDYIINR 797 AV+AL K FL L Y++ R Sbjct: 268 KAVDALEKFGEKADFLRSLAKYLLER 293 >B4BCZ4.1 B4BCZ4_CLOTM Polyprenyl synthetase Length = 298 Score = 161 bits (407), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 104/266 (39%), Positives = 147/266 (55%), Gaps = 5/266 (1%) Query: 536 KESLIEAANYSLTGDGKRIRPILTWVLGVEVYGLQAAAIEPLLRSLEFMHTASLIFDDLP 595 ++SL A YSL GKR+RP+L+ + ++ G + P ++E +HT SLI DDLP Sbjct: 32 EKSLYSAMRYSLMAGGKRLRPVLSLAV-CDMLGGSVEQVLPFACAVEMIHTYSLIHDDLP 90 Query: 596 SQDNASTRRGRPTLHQVHNSATAELTGLYLIQKA--IQEQASLRAFD--PAAVLALMHYS 651 + DN RRGRPT H+V+ A A L G L+ A I + ++ D + A + Sbjct: 91 AMDNDDFRRGRPTNHKVYGEALAILAGDGLLNLAFEIMLENIIKNGDMERKSKAAAVIAK 150 Query: 652 AEKAEDMCMGQAMDLHSKGKAMTLEQLNMMCFYKTGLAFEASLVMPAILAGVPQAEINAL 711 A M GQ +DL S+GK + E LN M KTG +A +V AIL G +I L Sbjct: 151 AAGMNGMIAGQVIDLESEGKQVDNEILNRMHRLKTGALIKAPVVSAAILCGADADDIQKL 210 Query: 712 KKYAYHAGIAFQIKDDLLDLEGDQQVLGKNTRMDAENNNSTFVSVLGAEAARFEMWDHYC 771 ++A + G+AFQIKDD+LD+EG + LGK DA+NN ST+V+V G E ++ + D Sbjct: 211 DEFAENLGLAFQIKDDILDVEGSSEKLGKKVGSDADNNKSTYVTVYGLEKSKEILSDVTK 270 Query: 772 HAVEALNAVPRKIAFLNHLLDYIINR 797 AV+AL K FL L Y++ R Sbjct: 271 KAVDALEKFGEKADFLRSLAKYLLER 296 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.134 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 4,509,800,911 Number of extensions: 183384484 Number of successful extensions: 458564 Number of sequences better than 1.0e-05: 3199 Number of HSP's gapped: 452656 Number of HSP's successfully gapped: 3201 Length of query: 799 Length of database: 3,060,696,203 Length adjustment: 144 Effective length of query: 655 Effective length of database: 1,704,070,043 Effective search space: 1116165878165 Effective search space used: 1116165878165 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 136 (57.0 bits)