BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0294.0007.p (535 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KKD6.1 B3KKD6_9BACI CTP synthase EC=6.3.4.2 962 0.0 B1DK77.1 B1DK77_9BACL CTP synthase EC=6.3.4.2 904 0.0 B4AJA2.1 B4AJA2_BACPU CTP synthase EC=6.3.4.2 826 0.0 A8FIE5.1 PYRG_BACP2 CTP synthase EC=6.3.4.2 826 0.0 Q65DT7.1 PYRG_BACLD CTP synthase EC=6.3.4.2 824 0.0 >B3KKD6.1 B3KKD6_9BACI CTP synthase EC=6.3.4.2 Length = 533 Score = 962 bits (2487), Expect = 0.0, Method: Compositional matrix adjust. Identities = 466/531 (87%), Positives = 493/531 (92%) Query: 1 VTKYIFVTGGVVSSLGKGITAASLGRLLKNRGLKVTIQKFDPYINVDPGTMSPYQHGEVF 60 +TKYIFVTGGVVSSLGKGITAASLGRLLKNRGLKVTIQKFDPYIN+DPGTMSPYQHGEVF Sbjct: 1 MTKYIFVTGGVVSSLGKGITAASLGRLLKNRGLKVTIQKFDPYINIDPGTMSPYQHGEVF 60 Query: 61 VTDDGAETDLDLGHYERFIDINLSKNSNVTTGKIYSSVISKERRGEYLGGTVQVIPHITN 120 VTDDGAETDLDLGHYERFIDINLSKNSNVTTGK+YSSVISKERRGEYLGGTVQVIPHITN Sbjct: 61 VTDDGAETDLDLGHYERFIDINLSKNSNVTTGKVYSSVISKERRGEYLGGTVQVIPHITN 120 Query: 121 EIKERVFRAGRETGSDVVITEIGGTVGDIESLPFLEAIRQIKSDIGRENVMYIHVTLIPY 180 EIKERVFRAGRE GSDVVITEIGGTVGDIESLPFLEAIRQIKSD+GRENVMYIHVTLIPY Sbjct: 121 EIKERVFRAGREAGSDVVITEIGGTVGDIESLPFLEAIRQIKSDVGRENVMYIHVTLIPY 180 Query: 181 IKAAGEVKTKPTQHSVKELRSIGIQPNVIVCRTEYALSDDMKAKIALFCDIDANAVVECR 240 IKAAGEVKTKPTQHSVKELRSIGIQPNVIVCRTE+ LS +MKAKIALFCDID NAVVECR Sbjct: 181 IKAAGEVKTKPTQHSVKELRSIGIQPNVIVCRTEHELSTEMKAKIALFCDIDPNAVVECR 240 Query: 241 DASTLYEVPLNLRDEGLDEIVVNHLKLTTPAPDMREWENMLGRIQKLERTVEIAIVGKYV 300 DAS+LYEVPLNLRDEGLDEIVVNHLKLTTPAPDM EWE+++ R+ KLE+TVEIAIVGKYV Sbjct: 241 DASSLYEVPLNLRDEGLDEIVVNHLKLTTPAPDMSEWEDLVERVSKLEKTVEIAIVGKYV 300 Query: 301 ALHDAYLSVVESLSHAGFAANAEVKVRWVDAELVTDENXXXXXXXXXXXXXXXXXXDRGI 360 ALHDAYLSVVESLSHAGF ANA+VK+RWV+AE +T +N DRGI Sbjct: 301 ALHDAYLSVVESLSHAGFDANADVKIRWVNAEEITADNVEETLNGIGGILVPGGFGDRGI 360 Query: 361 EGKISAIRYAREQSIPFFGICLGMQVSVIEYGRSILGLAGANSSEIDPATLHPLIDLLPE 420 EGKISAIRYARE +IPFFGICLGMQVSVIEY RSI+GL GANSSEIDPAT +P+IDLLPE Sbjct: 361 EGKISAIRYAREHNIPFFGICLGMQVSVIEYARSIVGLNGANSSEIDPATEYPVIDLLPE 420 Query: 421 QKDIEDMGGTMRLGLYPCKLLPESLAMSCYDDELVYERHRHRYEFNNAYRDEIEKAGLVI 480 QKDIED+GGTMRLGLYPCKL+P SLA SCY DELVYERHRHRYEFNN YR++IEKAGL I Sbjct: 421 QKDIEDLGGTMRLGLYPCKLVPGSLAESCYQDELVYERHRHRYEFNNQYREDIEKAGLRI 480 Query: 481 SGTSPDGRLVEIVELPGHPWFLSVQFHPEFTSRPNRPQPLFREFVKASLTH 531 SGTSPDGRLVEIVELPGHPWFL+VQFHPEFTSRPNRPQPLFREFVKAS+ H Sbjct: 481 SGTSPDGRLVEIVELPGHPWFLAVQFHPEFTSRPNRPQPLFREFVKASIQH 531 >B1DK77.1 B1DK77_9BACL CTP synthase EC=6.3.4.2 Length = 534 Score = 904 bits (2336), Expect = 0.0, Method: Compositional matrix adjust. Identities = 436/534 (81%), Positives = 481/534 (90%) Query: 1 VTKYIFVTGGVVSSLGKGITAASLGRLLKNRGLKVTIQKFDPYINVDPGTMSPYQHGEVF 60 +TKYIFVTGGVVSSLGKGITAASLGRLLKNRGLKVTIQKFDPYINVDPGTMSPYQHGEVF Sbjct: 1 MTKYIFVTGGVVSSLGKGITAASLGRLLKNRGLKVTIQKFDPYINVDPGTMSPYQHGEVF 60 Query: 61 VTDDGAETDLDLGHYERFIDINLSKNSNVTTGKIYSSVISKERRGEYLGGTVQVIPHITN 120 VTDDGAETDLDLGHYERFIDINL+K S+VTTGKIYS+VISKERRGEYLGGTVQVIPHITN Sbjct: 61 VTDDGAETDLDLGHYERFIDINLTKYSSVTTGKIYSNVISKERRGEYLGGTVQVIPHITN 120 Query: 121 EIKERVFRAGRETGSDVVITEIGGTVGDIESLPFLEAIRQIKSDIGRENVMYIHVTLIPY 180 EIKERV+RAG+E GSDVVITEIGGTVGDIESLPFLEAIRQIKSDIGR+NVMYIHVTLIPY Sbjct: 121 EIKERVYRAGKEAGSDVVITEIGGTVGDIESLPFLEAIRQIKSDIGRDNVMYIHVTLIPY 180 Query: 181 IKAAGEVKTKPTQHSVKELRSIGIQPNVIVCRTEYALSDDMKAKIALFCDIDANAVVECR 240 IKAAGEVKTKPTQHSVKELRSIGIQPNVIVCRTE+ALS+D+K KI LFCDIDANAVVEC Sbjct: 181 IKAAGEVKTKPTQHSVKELRSIGIQPNVIVCRTEHALSEDLKRKIGLFCDIDANAVVECI 240 Query: 241 DASTLYEVPLNLRDEGLDEIVVNHLKLTTPAPDMREWENMLGRIQKLERTVEIAIVGKYV 300 DASTLYEVPL LR++GLD+IVVNHLKLTT PDM +WE+++ R++ L +T EIAIVGKYV Sbjct: 241 DASTLYEVPLMLREQGLDDIVVNHLKLTTNQPDMTQWEDLVNRVKSLHKTTEIAIVGKYV 300 Query: 301 ALHDAYLSVVESLSHAGFAANAEVKVRWVDAELVTDENXXXXXXXXXXXXXXXXXXDRGI 360 ALHDAYLS+VE+L HAG+ A++EVK+RWV+AE + DEN DRGI Sbjct: 301 ALHDAYLSIVEALGHAGYDADSEVKLRWVNAEEIDDENVSEMLKGVHGILVPGGFGDRGI 360 Query: 361 EGKISAIRYAREQSIPFFGICLGMQVSVIEYGRSILGLAGANSSEIDPATLHPLIDLLPE 420 EGK+SAIRYAREQ IPFFGICLGMQV+VIEY RS+ GL ANS+EI+P+T +P+IDLLP+ Sbjct: 361 EGKVSAIRYAREQQIPFFGICLGMQVAVIEYARSVAGLFNANSAEINPSTPYPVIDLLPD 420 Query: 421 QKDIEDMGGTMRLGLYPCKLLPESLAMSCYDDELVYERHRHRYEFNNAYRDEIEKAGLVI 480 QKDIEDMGGTMRLGLYPCKL P SLA + Y+DELVYERHRHRYEFNN YR+ IE AGL I Sbjct: 421 QKDIEDMGGTMRLGLYPCKLKPGSLAATEYNDELVYERHRHRYEFNNEYRERIESAGLRI 480 Query: 481 SGTSPDGRLVEIVELPGHPWFLSVQFHPEFTSRPNRPQPLFREFVKASLTHSEQ 534 SGTSPDGRLVE+VELP HPWFL+VQFHPEFTSRPNRPQPLFR FV+A+L +S Q Sbjct: 481 SGTSPDGRLVEMVELPEHPWFLAVQFHPEFTSRPNRPQPLFRGFVRAALKYSGQ 534 >B4AJA2.1 B4AJA2_BACPU CTP synthase EC=6.3.4.2 Length = 535 Score = 826 bits (2133), Expect = 0.0, Method: Compositional matrix adjust. Identities = 387/533 (72%), Positives = 451/533 (84%) Query: 1 VTKYIFVTGGVVSSLGKGITAASLGRLLKNRGLKVTIQKFDPYINVDPGTMSPYQHGEVF 60 +TKYIFVTGGVVSSLGKGITAASLGRLLKNRG+ VTIQKFDPYINVDPGTMSPYQHGEVF Sbjct: 1 MTKYIFVTGGVVSSLGKGITAASLGRLLKNRGMDVTIQKFDPYINVDPGTMSPYQHGEVF 60 Query: 61 VTDDGAETDLDLGHYERFIDINLSKNSNVTTGKIYSSVISKERRGEYLGGTVQVIPHITN 120 VTDDGAETDLDLGHYERFIDINL+K SNVTTGKIYS+V+ KERRG+YLGGTVQVIPHITN Sbjct: 61 VTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSTVLKKERRGDYLGGTVQVIPHITN 120 Query: 121 EIKERVFRAGRETGSDVVITEIGGTVGDIESLPFLEAIRQIKSDIGRENVMYIHVTLIPY 180 EIK+RV+RAG+ETG+DVVITEIGGTVGDIESLPFLEAIRQ+KSDIGRENVMYIH TL+PY Sbjct: 121 EIKDRVYRAGKETGADVVITEIGGTVGDIESLPFLEAIRQMKSDIGRENVMYIHCTLVPY 180 Query: 181 IKAAGEVKTKPTQHSVKELRSIGIQPNVIVCRTEYALSDDMKAKIALFCDIDANAVVECR 240 I+AAGE+KTKPTQHSVKELRS+GIQPNVIV RTE ++ DMK KIALFCDID AV+EC+ Sbjct: 181 IRAAGELKTKPTQHSVKELRSLGIQPNVIVVRTEMPMTQDMKDKIALFCDIDTKAVIECQ 240 Query: 241 DASTLYEVPLNLRDEGLDEIVVNHLKLTTPAPDMREWENMLGRIQKLERTVEIAIVGKYV 300 DA TLY +PL+L+ +GLD++V H+KL DM EW ++ ++Q L + V I +VGKYV Sbjct: 241 DADTLYSIPLDLQKQGLDKLVCEHMKLDCQDADMTEWTALVDKVQNLSKQVTIGLVGKYV 300 Query: 301 ALHDAYLSVVESLSHAGFAANAEVKVRWVDAELVTDENXXXXXXXXXXXXXXXXXXDRGI 360 L DAY+SVVESL HAG+A +A+V+++W++AE VT EN DRG+ Sbjct: 301 ELQDAYISVVESLRHAGYAFDADVQIKWINAEEVTAENMADFAQDVDGIIVPGGFGDRGV 360 Query: 361 EGKISAIRYAREQSIPFFGICLGMQVSVIEYGRSILGLAGANSSEIDPATLHPLIDLLPE 420 EGKI A +YARE +PFFGICLGMQV+ IEY R++LGL GA+S+EIDP T P+IDLLPE Sbjct: 361 EGKIIATQYARENKVPFFGICLGMQVASIEYARNVLGLEGAHSAEIDPETAFPIIDLLPE 420 Query: 421 QKDIEDMGGTMRLGLYPCKLLPESLAMSCYDDELVYERHRHRYEFNNAYRDEIEKAGLVI 480 QKD++D+GGT+RLGLYPCKL +S A + Y+DE+VYERHRHRYEFNN +R ++E AG V Sbjct: 421 QKDVDDLGGTLRLGLYPCKLNEDSKAFAAYNDEVVYERHRHRYEFNNEFRQQMEAAGFVF 480 Query: 481 SGTSPDGRLVEIVELPGHPWFLSVQFHPEFTSRPNRPQPLFREFVKASLTHSE 533 SGTSPDGRLVEI+EL HPWFL+ QFHPEF SRP RPQPLFR+FV ASL SE Sbjct: 481 SGTSPDGRLVEIIELKDHPWFLASQFHPEFVSRPTRPQPLFRDFVGASLQASE 533 >A8FIE5.1 PYRG_BACP2 CTP synthase EC=6.3.4.2 Length = 535 Score = 826 bits (2133), Expect = 0.0, Method: Compositional matrix adjust. Identities = 387/533 (72%), Positives = 451/533 (84%) Query: 1 VTKYIFVTGGVVSSLGKGITAASLGRLLKNRGLKVTIQKFDPYINVDPGTMSPYQHGEVF 60 +TKYIFVTGGVVSSLGKGITAASLGRLLKNRG+ VTIQKFDPYINVDPGTMSPYQHGEVF Sbjct: 1 MTKYIFVTGGVVSSLGKGITAASLGRLLKNRGMDVTIQKFDPYINVDPGTMSPYQHGEVF 60 Query: 61 VTDDGAETDLDLGHYERFIDINLSKNSNVTTGKIYSSVISKERRGEYLGGTVQVIPHITN 120 VTDDGAETDLDLGHYERFIDINL+K SNVTTGKIYS+V+ KERRG+YLGGTVQVIPHITN Sbjct: 61 VTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSTVLKKERRGDYLGGTVQVIPHITN 120 Query: 121 EIKERVFRAGRETGSDVVITEIGGTVGDIESLPFLEAIRQIKSDIGRENVMYIHVTLIPY 180 EIK+RV+RAG+ETG+DVVITEIGGTVGDIESLPFLEAIRQ+KSDIGRENVMYIH TL+PY Sbjct: 121 EIKDRVYRAGKETGADVVITEIGGTVGDIESLPFLEAIRQMKSDIGRENVMYIHCTLVPY 180 Query: 181 IKAAGEVKTKPTQHSVKELRSIGIQPNVIVCRTEYALSDDMKAKIALFCDIDANAVVECR 240 I+AAGE+KTKPTQHSVKELRS+GIQPNVIV RTE ++ DMK KIALFCDID AV+EC+ Sbjct: 181 IRAAGELKTKPTQHSVKELRSLGIQPNVIVVRTEMPMTQDMKDKIALFCDIDTKAVIECQ 240 Query: 241 DASTLYEVPLNLRDEGLDEIVVNHLKLTTPAPDMREWENMLGRIQKLERTVEIAIVGKYV 300 DA TLY +PL+L+ +GLD++V H+KL DM EW ++ ++Q L + V I +VGKYV Sbjct: 241 DADTLYSIPLDLQKQGLDKLVCEHMKLDCQDADMTEWTALVDKVQNLSKQVTIGLVGKYV 300 Query: 301 ALHDAYLSVVESLSHAGFAANAEVKVRWVDAELVTDENXXXXXXXXXXXXXXXXXXDRGI 360 L DAY+SVVESL HAG+A +A+V+++W++AE VT EN DRG+ Sbjct: 301 ELQDAYISVVESLRHAGYAFDADVQIKWINAEEVTAENMADFAQDVDGIIVPGGFGDRGV 360 Query: 361 EGKISAIRYAREQSIPFFGICLGMQVSVIEYGRSILGLAGANSSEIDPATLHPLIDLLPE 420 EGKI A +YARE +PFFGICLGMQV+ IEY R++LGL GA+S+EIDP T P+IDLLPE Sbjct: 361 EGKIIATQYARENKVPFFGICLGMQVASIEYARNVLGLEGAHSAEIDPETAFPIIDLLPE 420 Query: 421 QKDIEDMGGTMRLGLYPCKLLPESLAMSCYDDELVYERHRHRYEFNNAYRDEIEKAGLVI 480 QKD++D+GGT+RLGLYPCKL +S A + Y+DE+VYERHRHRYEFNN +R ++E AG V Sbjct: 421 QKDVDDLGGTLRLGLYPCKLNEDSKAFAAYNDEVVYERHRHRYEFNNEFRQQMEAAGFVF 480 Query: 481 SGTSPDGRLVEIVELPGHPWFLSVQFHPEFTSRPNRPQPLFREFVKASLTHSE 533 SGTSPDGRLVEI+EL HPWFL+ QFHPEF SRP RPQPLFR+FV ASL SE Sbjct: 481 SGTSPDGRLVEIIELKDHPWFLASQFHPEFVSRPTRPQPLFRDFVGASLQASE 533 >Q65DT7.1 PYRG_BACLD CTP synthase EC=6.3.4.2 Length = 535 Score = 824 bits (2128), Expect = 0.0, Method: Compositional matrix adjust. Identities = 389/535 (72%), Positives = 457/535 (85%) Query: 1 VTKYIFVTGGVVSSLGKGITAASLGRLLKNRGLKVTIQKFDPYINVDPGTMSPYQHGEVF 60 +TKYIFVTGGVVSSLGKGITA+SLGRLLKNRGL VTIQKFDPYINVDPGTMSPYQHGEVF Sbjct: 1 MTKYIFVTGGVVSSLGKGITASSLGRLLKNRGLNVTIQKFDPYINVDPGTMSPYQHGEVF 60 Query: 61 VTDDGAETDLDLGHYERFIDINLSKNSNVTTGKIYSSVISKERRGEYLGGTVQVIPHITN 120 VTDDGAETDLDLGHYERFIDINL+K SNVTTGKIYS+V+ KERRG+YLGGTVQVIPHITN Sbjct: 61 VTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSTVLKKERRGDYLGGTVQVIPHITN 120 Query: 121 EIKERVFRAGRETGSDVVITEIGGTVGDIESLPFLEAIRQIKSDIGRENVMYIHVTLIPY 180 EIK+RVFRAG+ET +DVVITEIGGTVGDIESLPFLEAIRQIKSD+GR+NVMYIH TL+PY Sbjct: 121 EIKDRVFRAGKETHADVVITEIGGTVGDIESLPFLEAIRQIKSDVGRDNVMYIHCTLVPY 180 Query: 181 IKAAGEVKTKPTQHSVKELRSIGIQPNVIVCRTEYALSDDMKAKIALFCDIDANAVVECR 240 +KAAGE+KTKPTQHSVKELRS+GIQPNVIV RTE +S DMK KIALFCDID AV+E Sbjct: 181 LKAAGEMKTKPTQHSVKELRSLGIQPNVIVVRTEMPISQDMKDKIALFCDIDPKAVIEAG 240 Query: 241 DASTLYEVPLNLRDEGLDEIVVNHLKLTTPAPDMREWENMLGRIQKLERTVEIAIVGKYV 300 DA TLY +PL+L+ +GLD +V +HLKL DM EW+ ++ +++ L +TV IA+VGKYV Sbjct: 241 DADTLYSIPLDLQKQGLDSLVCSHLKLDCREADMEEWKELVKKVKNLSKTVTIALVGKYV 300 Query: 301 ALHDAYLSVVESLSHAGFAANAEVKVRWVDAELVTDENXXXXXXXXXXXXXXXXXXDRGI 360 L DAY+SVVESL HAG+A +A+++V+W++AE VT++N DRG+ Sbjct: 301 ELPDAYISVVESLRHAGYAFDADIQVKWINAEEVTEDNVADLVQNADGILVPGGFGDRGV 360 Query: 361 EGKISAIRYAREQSIPFFGICLGMQVSVIEYGRSILGLAGANSSEIDPATLHPLIDLLPE 420 EGKI+ ++YAREQ IPFFGICLGMQV+ IEY R++LGL GA+S+EIDP+T +P+IDLLPE Sbjct: 361 EGKITTVKYAREQKIPFFGICLGMQVASIEYARNVLGLEGAHSAEIDPSTPYPIIDLLPE 420 Query: 421 QKDIEDMGGTMRLGLYPCKLLPESLAMSCYDDELVYERHRHRYEFNNAYRDEIEKAGLVI 480 QKDIED+GGT+RLGLYPCKL S A Y++E+VYERHRHRYEFNN +R ++E+AG V Sbjct: 421 QKDIEDLGGTLRLGLYPCKLQEGSKAYQAYENEVVYERHRHRYEFNNEFRQQMEEAGFVF 480 Query: 481 SGTSPDGRLVEIVELPGHPWFLSVQFHPEFTSRPNRPQPLFREFVKASLTHSEQL 535 SGTSPDGRLVEI+EL HPWF++ QFHPEFTSRP RPQ LFR+FV ASL SE+L Sbjct: 481 SGTSPDGRLVEIIELKDHPWFVASQFHPEFTSRPTRPQALFRDFVHASLKTSEKL 535 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.137 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,110,191,064 Number of extensions: 130642738 Number of successful extensions: 338539 Number of sequences better than 1.0e-05: 2057 Number of HSP's gapped: 332577 Number of HSP's successfully gapped: 2148 Length of query: 535 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 394 Effective length of database: 1,732,333,088 Effective search space: 682539236672 Effective search space used: 682539236672 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 134 (56.2 bits)