BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0290.0052.p (390 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KG04.1 B3KG04_9BACI Oxygen-independent coproporphyrinogen III ... 602 e-170 B1DFS5.1 B1DFS5_9BACL Oxygen-independent coproporphyrinogen III ... 485 e-135 C0ZB45.1 C0ZB45_BREBN Putative oxygen-independent coproporphyrin... 424 e-117 C2C1Y6.1 C2C1Y6_LISGR Coproporphyrinogen dehydrogenase EC=1.3.99.22 358 7e-97 P54304.3 HEMN_BACSU Oxygen-independent coproporphyrinogen-III ox... 357 8e-97 >B3KG04.1 B3KG04_9BACI Oxygen-independent coproporphyrinogen III oxidase EC=1.3.99.22 Length = 388 Score = 602 bits (1552), Expect = e-170, Method: Compositional matrix adjust. Identities = 278/383 (72%), Positives = 325/383 (84%) Query: 6 NGRPPEAVYIHIPFCTNKCFYCDFNSYVLKDQPVMDYLRALDREMEMTVKHTTPGVIKTI 65 N + EAVYIHIPFCTNKCFYCDFNSYVLKDQPVMDYLRALD+EME+TV+ PG IK+I Sbjct: 4 NDQRTEAVYIHIPFCTNKCFYCDFNSYVLKDQPVMDYLRALDKEMELTVQANPPGRIKSI 63 Query: 66 FVGGGTPTVLKPEEMAYFLKSVRTHFPQWDENIEFSMEANPGTTDKDKLAVMKEGGVNRV 125 FVGGGTPTVLKP EM YFL+SV+ HFP+W ++IEFSMEANPGTTD +KL+VM++GGVNR+ Sbjct: 64 FVGGGTPTVLKPNEMEYFLQSVKRHFPEWSDSIEFSMEANPGTTDLEKLSVMRQGGVNRI 123 Query: 126 SFGVQAFQNELLSGIGRIHNVDDVYRSLENARSVGLHNLSVDLMFGLPNQTVDMLRESVS 185 SFGVQAFQN LL+GIGRIH+ DDVYRSL+NAR G N+S+DLMFGLPNQT+DML ESV Sbjct: 124 SFGVQAFQNTLLTGIGRIHDTDDVYRSLDNARRAGFDNMSIDLMFGLPNQTLDMLAESVD 183 Query: 186 KALELNLPHYSIYSLKVEENTLFHTLFNKNKLPLPSXXXXXXXXXXXXSTMEAAGYGQYE 245 KALEL LPHYSIYSLKVEENTLFHT++ +N+LPLP M+AAGY QYE Sbjct: 184 KALELELPHYSIYSLKVEENTLFHTMYQRNQLPLPDEEDELNMYLLLMERMKAAGYKQYE 243 Query: 246 ISNFAKPGMESRHNITYWRNEDYYGLGAGAHGYVKRQRHMNIKGVNPYIEASHSGLPRLD 305 ISNFAKPG ESRHN+TYWRNEDYYGLGAGAHGYV RQRH+NIKGVNPY EA++ GLPRL+ Sbjct: 244 ISNFAKPGFESRHNMTYWRNEDYYGLGAGAHGYVGRQRHVNIKGVNPYNEAANKGLPRLE 303 Query: 306 TFRISEQEAMEDFMMVGLRMREGVSDQAFRAQFGKSLQDIFAGSLKKMLAAGLIEQNGDA 365 +F IS++EAMEDF+MVGLR+ +GVS FR QFG S++D+FAG L KM+ AGL++ + Sbjct: 304 SFEISKEEAMEDFLMVGLRVLDGVSRSRFREQFGISMEDVFAGPLNKMVGAGLLDATEEG 363 Query: 366 YRLSKQGILFGNDVFGEFVGVLT 388 Y+LS +GILFGNDVFGEF+G LT Sbjct: 364 YKLSSKGILFGNDVFGEFIGSLT 386 >B1DFS5.1 B1DFS5_9BACL Oxygen-independent coproporphyrinogen III oxidase EC=1.3.99.22 Length = 392 Score = 485 bits (1249), Expect = e-135, Method: Compositional matrix adjust. Identities = 237/386 (61%), Positives = 290/386 (75%), Gaps = 6/386 (1%) Query: 10 PEAVYIHIPFCTNKCFYCDFNSYVLKDQPVMDYLRALDREMEMTVKHTTPGVIKTIFVGG 69 P+A+YIHIPFCTNKC YCDF SYVLK QPV +YL AL+REM +TV P I T+FVGG Sbjct: 6 PKALYIHIPFCTNKCHYCDFTSYVLKGQPVDEYLDALEREMALTVAQMPPERIDTVFVGG 65 Query: 70 GTPTVLKPEEMAYFLKSVRTHFPQWDENIEFSMEANPGTTDKDKLAVMKEGGVNRVSFGV 129 GTPTVL P +M FL SV+ +FP D ++EF+MEANPGTTD +KLA M GGVNR+SFGV Sbjct: 66 GTPTVLTPPQMERFLTSVKKYFPLAD-DVEFTMEANPGTTDPEKLAAMFAGGVNRISFGV 124 Query: 130 QAFQNELLSGIGRIHNVDDVYRSLENARSVGLHNLSVDLMFGLPNQTVDMLRESVSKALE 189 Q+F N LL IGRIHNVDDVYRSLENAR+ G NLS+DLMFGLP QTV+ML +SV+KAL Sbjct: 125 QSFDNGLLERIGRIHNVDDVYRSLENARAAGFTNLSIDLMFGLPKQTVEMLEDSVNKALA 184 Query: 190 LNLPHYSIYSLKVEENTLFHTLFNKNKLPLPSXXXXXXXXXXXXSTMEAAGYGQYEISNF 249 L+LPHYS+YSLKVEENTLFH L+ +++LPLP ++ AGY YEISNF Sbjct: 185 LDLPHYSLYSLKVEENTLFHKLYQRDELPLPPEDEEFNMYTLLMDRLKQAGYVHYEISNF 244 Query: 250 AKPGMESRHNITYWRNEDYYGLGAGAHGYVKRQRHMNIKGVNPYIEASHSGLPRLDTFRI 309 AKPG ESRHN TYWRNE YYGLGAGAHGY + RH+N+KGV P+I+ + + LPRL+ + Sbjct: 245 AKPGYESRHNSTYWRNEPYYGLGAGAHGYARGLRHVNVKGVQPFIDYTKTKLPRLEENVV 304 Query: 310 SEQEAMEDFMMVGLRMREGVSDQAFRAQF-GKSLQDIFAGSLKKMLAAGLIE---QNGDA 365 E EAMEDFMMVGLR+ +GV + AQF G+ L+D F ++K+L GL+E + GD Sbjct: 305 PEYEAMEDFMMVGLRLLKGVRTSDYAAQFEGQKLEDKFGPIIEKLLKDGLLEKVLEEGDT 364 Query: 366 -YRLSKQGILFGNDVFGEFVGVLTEV 390 Y+L+ +G+LFGNDVFG F+G+ E Sbjct: 365 IYKLTDKGVLFGNDVFGSFIGLEEEA 390 >C0ZB45.1 C0ZB45_BREBN Putative oxygen-independent coproporphyrinogen III oxidase Length = 379 Score = 424 bits (1091), Expect = e-117, Method: Compositional matrix adjust. Identities = 200/377 (53%), Positives = 269/377 (71%), Gaps = 2/377 (0%) Query: 10 PEAVYIHIPFCTNKCFYCDFNSYVLKD-QPVMDYLRALDREMEMTVKHTTPGVIKTIFVG 68 P++VYIHIPFCTNKC+YCDFNS+V + Q + DYL AL EME+T +KTIFVG Sbjct: 2 PQSVYIHIPFCTNKCYYCDFNSFVTNNPQLIWDYLDALKSEMEITFSQQLIEQVKTIFVG 61 Query: 69 GGTPTVLKPEEMAYFLKSVRTHFPQ-WDENIEFSMEANPGTTDKDKLAVMKEGGVNRVSF 127 GGTPT L +M FL+ V+ + W ++IEFSMEANPGTTD +KL +M+E GVNR+SF Sbjct: 62 GGTPTFLDHAQMRAFLEMVQKQLGKYWTDDIEFSMEANPGTTDVEKLRIMRELGVNRLSF 121 Query: 128 GVQAFQNELLSGIGRIHNVDDVYRSLENARSVGLHNLSVDLMFGLPNQTVDMLRESVSKA 187 GVQ+F + LL +GRIH+ + VYRS++NA+ VG N S+DLMFGLP+QT+D+ R+++ KA Sbjct: 122 GVQSFDDALLKRLGRIHDQEAVYRSIDNAKKVGFDNFSIDLMFGLPDQTLDIFRQTLDKA 181 Query: 188 LELNLPHYSIYSLKVEENTLFHTLFNKNKLPLPSXXXXXXXXXXXXSTMEAAGYGQYEIS 247 L H+S YSLKVEENTLFHTL+ K++LPLPS ME GY QYEIS Sbjct: 182 FGLGTTHFSAYSLKVEENTLFHTLYQKDQLPLPSEETELEMYMVLIEEMERHGYKQYEIS 241 Query: 248 NFAKPGMESRHNITYWRNEDYYGLGAGAHGYVKRQRHMNIKGVNPYIEASHSGLPRLDTF 307 NFAKPG ES+HN TYW N +YYGLGAGAHGYV RH+N + Y++ GLPR++ F Sbjct: 242 NFAKPGFESKHNKTYWLNREYYGLGAGAHGYVCGHRHVNAGPLAIYLQKCKEGLPRVEQF 301 Query: 308 RISEQEAMEDFMMVGLRMREGVSDQAFRAQFGKSLQDIFAGSLKKMLAAGLIEQNGDAYR 367 + ++AME+ M++GLR+REGV AF ++FG ++ D+F +++ +A G++E+ G + Sbjct: 302 EVPREDAMEEQMILGLRLREGVDLSAFASRFGATVHDVFGTIIEEEVAKGMLEEKGGFLK 361 Query: 368 LSKQGILFGNDVFGEFV 384 L+KQG+ GN+VF F+ Sbjct: 362 LTKQGLPLGNEVFARFL 378 >C2C1Y6.1 C2C1Y6_LISGR Coproporphyrinogen dehydrogenase EC=1.3.99.22 Length = 375 Score = 358 bits (918), Expect = 7e-97, Method: Compositional matrix adjust. Identities = 178/374 (47%), Positives = 239/374 (63%), Gaps = 2/374 (0%) Query: 12 AVYIHIPFCTNKCFYCDFNSYVLKDQPVMDYLRALDREMEMTVKHTTPGVIKTIFVGGGT 71 +VYIHIPFC + C+YCDFN L+ QPV Y+ L REMEM I T+FVGGGT Sbjct: 3 SVYIHIPFCEHICYYCDFNKVFLEGQPVDRYVDLLIREMEMVTGKQELEPIDTVFVGGGT 62 Query: 72 PTVLKPEEMAYFLKSVRTHFPQWDENIEFSMEANPGTTDKDKLAVMKEGGVNRVSFGVQA 131 PT L +++A ++ P EN EFS EANPG +K+ V+K+ GVNR+S GVQ+ Sbjct: 63 PTTLNEKQLARLCTAIHRLLP-LRENAEFSFEANPGDLSLEKIQVLKDHGVNRISMGVQS 121 Query: 132 FQNELLSGIGRIHNVDDVYRSLENARSVGLHNLSVDLMFGLPNQTVDMLRESVSKALELN 191 F NELL IGRIH DVY+S++N R +GL N+S+DL+F LP QT ++++++AL+L+ Sbjct: 122 FNNELLKKIGRIHTTKDVYQSVDNLRKIGLDNVSIDLIFSLPTQTFADFKDTLTQALDLD 181 Query: 192 LPHYSIYSLKVEENTLFHTLFNKNKLPLPSXXXXXXXXXXXXSTMEAAGYGQYEISNFAK 251 LPHYS YSL +E T+F+ L K +L LP + ME G QYEISNFAK Sbjct: 182 LPHYSAYSLIIEPKTIFYNLMQKGQLILPKQEIEANMYDTLMNEMEKHGRRQYEISNFAK 241 Query: 252 PGMESRHNITYWRNEDYYGLGAGAHGYVKRQRHMNIKGVNPYIEASHSG-LPRLDTFRIS 310 PG ESRHNI YW NE YYG GAGAHGY+ QR+ N + Y+E +G LP + + Sbjct: 242 PGFESRHNIVYWSNEHYYGFGAGAHGYLGEQRYSNFGPIKKYMEPLENGELPVFQSRVLP 301 Query: 311 EQEAMEDFMMVGLRMREGVSDQAFRAQFGKSLQDIFAGSLKKMLAAGLIEQNGDAYRLSK 370 QE ME+ M +GLR +GVS F +FG++L D+F +++K LA GL+ +N + L++ Sbjct: 302 LQEKMEEEMFLGLRKVDGVSKAHFLQKFGQNLNDVFPHAIEKTLAEGLLYENEERIALTR 361 Query: 371 QGILFGNDVFGEFV 384 G GN+VF EF+ Sbjct: 362 DGRFLGNNVFQEFI 375 >P54304.3 HEMN_BACSU Oxygen-independent coproporphyrinogen-III oxidase 1 EC=1.3.99.22 Length = 379 Score = 357 bits (917), Expect = 8e-97, Method: Compositional matrix adjust. Identities = 176/378 (46%), Positives = 238/378 (62%), Gaps = 1/378 (0%) Query: 11 EAVYIHIPFCTNKCFYCDFNSYVLKDQPVMDYLRALDREMEMTVKHTTPGVIKTIFVGGG 70 ++ YIHIPFC + C YCDFN Y ++ QPV +YL AL++EM T+ T +KTIF+GGG Sbjct: 2 KSAYIHIPFCEHICHYCDFNKYFIQSQPVDEYLNALEQEMINTIAKTGQPDLKTIFIGGG 61 Query: 71 TPTVLKPEEMAYFLKSVRTHFPQWDENIEFSMEANPGTTDKDKLAVMKEGGVNRVSFGVQ 130 TPT L E++ + + + EF++EANP +KL ++KE GVNR+SFGVQ Sbjct: 62 TPTSLSEEQLKKLMDMINRVLKPSSDLSEFAVEANPDDLSAEKLKILKEAGVNRLSFGVQ 121 Query: 131 AFQNELLSGIGRIHNVDDVYRSLENARSVGLHNLSVDLMFGLPNQTVDMLRESVSKALEL 190 F+++LL IGR+H DV+ S E AR +G N+S+DLMFGLP QT+ L S++ AL L Sbjct: 122 TFEDDLLEKIGRVHKQKDVFTSFERAREIGFENISLDLMFGLPGQTLKHLEHSINTALSL 181 Query: 191 NLPHYSIYSLKVEENTLFHTLFNKNKLPLPSXXXXXXXXXXXXSTMEAAGYGQYEISNFA 250 + HYS+YSL VE T+F+ L K +L LP S MEA G QYEISNFA Sbjct: 182 DAEHYSVYSLIVEPKTVFYNLMQKGRLHLPPQEQEAEMYEIVMSKMEAHGIHQYEISNFA 241 Query: 251 KPGMESRHNITYWRNEDYYGLGAGAHGYVKRQRHMNIKGVNPYIE-ASHSGLPRLDTFRI 309 K GMES+HN+TYW NE Y+G GAGAHGY+ R +N+ V YI+ + G P DT + Sbjct: 242 KAGMESKHNLTYWSNEQYFGFGAGAHGYIGGTRTVNVGPVKHYIDLIAEKGFPYRDTHEV 301 Query: 310 SEQEAMEDFMMVGLRMREGVSDQAFRAQFGKSLQDIFAGSLKKMLAAGLIEQNGDAYRLS 369 + +E +E+ M +GLR GVS + F ++G+SL +F LK + GLI + A L+ Sbjct: 302 TTEEQIEEEMFLGLRKTAGVSKKRFAEKYGRSLDGLFPSVLKDLAEKGLIHNSESAVYLT 361 Query: 370 KQGILFGNDVFGEFVGVL 387 QG L GN+VFG F+G L Sbjct: 362 HQGKLLGNEVFGAFLGEL 379 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.137 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,300,223,342 Number of extensions: 93934803 Number of successful extensions: 215066 Number of sequences better than 1.0e-05: 2677 Number of HSP's gapped: 207698 Number of HSP's successfully gapped: 2685 Length of query: 390 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 252 Effective length of database: 1,760,596,133 Effective search space: 443670225516 Effective search space used: 443670225516 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 132 (55.5 bits)