BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0290.0040.p (214 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q2B7P8.1 Q2B7P8_9BACI Keto-hydroxyglutarate-aldolase/keto-deoxy-... 250 5e-65 Q832G3.1 Q832G3_ENTFA 2-dehydro-3-deoxyphosphogluconate aldolase... 238 2e-61 C2JQJ5.1 C2JQJ5_ENTFA Keto-hydroxyglutarate-aldolase/keto-deoxy-... 238 2e-61 C0X0N7.1 C0X0N7_ENTFA Keto-hydroxyglutarate-aldolase/keto-deoxy-... 238 2e-61 B1BAQ2.1 B1BAQ2_CLOBO Khg/kdpg aldolase EC=4.1.2.14 EC=4.1.3.16 238 2e-61 >Q2B7P8.1 Q2B7P8_9BACI Keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase Length = 209 Score = 250 bits (639), Expect = 5e-65, Method: Compositional matrix adjust. Identities = 118/200 (59%), Positives = 152/200 (76%), Gaps = 2/200 (1%) Query: 15 GVVAVIRADNADDAVKMSAACIEGGLNNIEVTFTTPDADVAIKRLAAEYG--SRAVIGAG 72 GVVAV+RAD+ ++AVK+S AC++GG+ IE+TFT A+ +K L+ + SRAV+GAG Sbjct: 5 GVVAVVRADSREEAVKISEACVKGGIAGIEITFTIDGAEAVLKELSGYFADDSRAVLGAG 64 Query: 73 TVLDPLTARIAILAGXXXXXXXXXXXXTAKMCNLYGIPYMPGCMTLNEMKEALKLGVDVL 132 TVLD TARIAILAG TAK+CNLY +PYMPGCMT+ EMKEAL+ G D++ Sbjct: 65 TVLDAATARIAILAGAEFIVSPAFDRETAKLCNLYQVPYMPGCMTITEMKEALEYGADII 124 Query: 133 KLFPGSAFGPDYVKAVKGPMPHVNIMPTGGVDLNNMEKWIANGCIAVGIGGNLTAPAKEG 192 KLFPG+AFGPD++KAVK P+P NIMPTGGV L N +WI NGC+AVG+GGNL APAK G Sbjct: 125 KLFPGNAFGPDFIKAVKSPLPQANIMPTGGVSLENAGEWIRNGCVAVGVGGNLAAPAKTG 184 Query: 193 RYDQITELAAKYVAKFKEIK 212 Y++ITE++A+Y+ KE + Sbjct: 185 NYEKITEMSAEYIKIVKEAR 204 >Q832G3.1 Q832G3_ENTFA 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase, putative Length = 215 Score = 238 bits (608), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 111/213 (52%), Positives = 153/213 (71%), Gaps = 2/213 (0%) Query: 2 MKKIKVLQNITSVGVVAVIRADNADDAVKMSAACIEGGLNNIEVTFTTPDADVAIKRLAA 61 MKK++VL+ + + GV+AV+RAD+ ++A+K+S A +EGG+ +E+TFT P AD I+ L Sbjct: 1 MKKVEVLKRLENAGVIAVLRADSKEEALKISHAVVEGGMIGLELTFTVPQADEVIRSLVE 60 Query: 62 EYGSRA--VIGAGTVLDPLTARIAILAGXXXXXXXXXXXXTAKMCNLYGIPYMPGCMTLN 119 Y VIGAGTVLD +TAR+AI+AG TA++CNLY +PY+PGCMT+ Sbjct: 61 TYHDEKDIVIGAGTVLDAVTARLAIMAGAEFIVSPSFNRETAEICNLYQVPYLPGCMTIT 120 Query: 120 EMKEALKLGVDVLKLFPGSAFGPDYVKAVKGPMPHVNIMPTGGVDLNNMEKWIANGCIAV 179 EM+ ALK GVD++KLFPGS +GP + A + P+P++NIMPTGGV L+NM W G AV Sbjct: 121 EMQTALKSGVDIVKLFPGSTYGPSIISAFQAPLPYLNIMPTGGVSLDNMASWFEAGVTAV 180 Query: 180 GIGGNLTAPAKEGRYDQITELAAKYVAKFKEIK 212 G+GGNL A AK G + ++T LA +Y+AKF+EIK Sbjct: 181 GVGGNLLAHAKTGEFGKVTALAKQYMAKFREIK 213 >C2JQJ5.1 C2JQJ5_ENTFA Keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase EC=4.1.3.16 Length = 215 Score = 238 bits (608), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 111/213 (52%), Positives = 153/213 (71%), Gaps = 2/213 (0%) Query: 2 MKKIKVLQNITSVGVVAVIRADNADDAVKMSAACIEGGLNNIEVTFTTPDADVAIKRLAA 61 MKK++VL+ + + GV+AV+RAD+ ++A+K+S A +EGG+ +E+TFT P AD I+ L Sbjct: 1 MKKVEVLKRLENAGVIAVLRADSKEEALKISHAVVEGGMIGLELTFTVPQADEVIRSLVE 60 Query: 62 EYGSRA--VIGAGTVLDPLTARIAILAGXXXXXXXXXXXXTAKMCNLYGIPYMPGCMTLN 119 Y VIGAGTVLD +TAR+AI+AG TA++CNLY +PY+PGCMT+ Sbjct: 61 TYHDEKDIVIGAGTVLDAVTARLAIMAGAEFIVSPSFNRETAEICNLYQVPYLPGCMTIT 120 Query: 120 EMKEALKLGVDVLKLFPGSAFGPDYVKAVKGPMPHVNIMPTGGVDLNNMEKWIANGCIAV 179 EM+ ALK GVD++KLFPGS +GP + A + P+P++NIMPTGGV L+NM W G AV Sbjct: 121 EMQTALKSGVDIVKLFPGSTYGPSIISAFQAPLPYLNIMPTGGVSLDNMASWFEAGVTAV 180 Query: 180 GIGGNLTAPAKEGRYDQITELAAKYVAKFKEIK 212 G+GGNL A AK G + ++T LA +Y+AKF+EIK Sbjct: 181 GVGGNLLAHAKTGEFGKVTALAKQYMAKFREIK 213 >C0X0N7.1 C0X0N7_ENTFA Keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase EC=4.1.3.16 Length = 215 Score = 238 bits (608), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 111/213 (52%), Positives = 153/213 (71%), Gaps = 2/213 (0%) Query: 2 MKKIKVLQNITSVGVVAVIRADNADDAVKMSAACIEGGLNNIEVTFTTPDADVAIKRLAA 61 MKK++VL+ + + GV+AV+RAD+ ++A+K+S A +EGG+ +E+TFT P AD I+ L Sbjct: 1 MKKVEVLKRLENAGVIAVLRADSKEEALKISHAVVEGGMIGLELTFTVPQADEVIRSLVE 60 Query: 62 EYGSRA--VIGAGTVLDPLTARIAILAGXXXXXXXXXXXXTAKMCNLYGIPYMPGCMTLN 119 Y VIGAGTVLD +TAR+AI+AG TA++CNLY +PY+PGCMT+ Sbjct: 61 TYHDEKDIVIGAGTVLDAVTARLAIMAGAEFIVSPSFNRETAEICNLYQVPYLPGCMTIT 120 Query: 120 EMKEALKLGVDVLKLFPGSAFGPDYVKAVKGPMPHVNIMPTGGVDLNNMEKWIANGCIAV 179 EM+ ALK GVD++KLFPGS +GP + A + P+P++NIMPTGGV L+NM W G AV Sbjct: 121 EMQTALKSGVDIVKLFPGSTYGPSIISAFQAPLPYLNIMPTGGVSLDNMASWFEAGVTAV 180 Query: 180 GIGGNLTAPAKEGRYDQITELAAKYVAKFKEIK 212 G+GGNL A AK G + ++T LA +Y+AKF+EIK Sbjct: 181 GVGGNLLAHAKTGEFGKVTALAKQYMAKFREIK 213 >B1BAQ2.1 B1BAQ2_CLOBO Khg/kdpg aldolase EC=4.1.2.14 EC=4.1.3.16 Length = 218 Score = 238 bits (607), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 113/211 (53%), Positives = 153/211 (72%), Gaps = 1/211 (0%) Query: 1 MMKKIKVLQNITSVGVVAVIRADNADDAVKMSAACIEGGLNNIEVTFTTPDADVAIKRLA 60 MMKKI+VL+ I VGV+AV+RAD+ + A+K+S ACI GG++ IEVTFT DAD IKRL Sbjct: 1 MMKKIRVLEKIIKVGVIAVVRADSVEQALKVSEACITGGISAIEVTFTVNDADKVIKRLK 60 Query: 61 AEYGSRA-VIGAGTVLDPLTARIAILAGXXXXXXXXXXXXTAKMCNLYGIPYMPGCMTLN 119 E+ ++GAGT+LD TAR AIL G TAK+CN Y +PYM GCMT+ Sbjct: 61 QEFSKEELIVGAGTILDSETARTAILNGAEYIVSPGFDLETAKLCNRYQVPYMAGCMTVT 120 Query: 120 EMKEALKLGVDVLKLFPGSAFGPDYVKAVKGPMPHVNIMPTGGVDLNNMEKWIANGCIAV 179 E+ +A+++GVD++KLFPGSA+GP VKA+K P+P I+PTGGV + N+++WI +GC+AV Sbjct: 121 EIIKAMEVGVDIIKLFPGSAYGPSIVKAIKDPIPQAPIIPTGGVSIENVKEWIKSGCVAV 180 Query: 180 GIGGNLTAPAKEGRYDQITELAAKYVAKFKE 210 G+GG+LT AK G Y+ ITE A K+V + K+ Sbjct: 181 GVGGSLTKSAKTGNYELITETAKKFVEEVKK 211 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,191,172,154 Number of extensions: 46797393 Number of successful extensions: 119889 Number of sequences better than 1.0e-05: 1309 Number of HSP's gapped: 117352 Number of HSP's successfully gapped: 1309 Length of query: 214 Length of database: 3,060,696,203 Length adjustment: 130 Effective length of query: 84 Effective length of database: 1,835,964,253 Effective search space: 154220997252 Effective search space used: 154220997252 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 128 (53.9 bits)