BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0290.0036.p (585 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q97FI3.1 Q97FI3_CLOAB MDR-type ABC transporter (Membrane associa... 633 e-179 B0K4H9.1 B0K4H9_THEPX ABC transporter related 491 e-136 B0KAL3.1 B0KAL3_THEP3 ABC transporter related 489 e-136 B7R6K1.1 B7R6K1_9THEO ABC transporter, ATP-binding protein 472 e-131 Q8RBI1.1 Q8RBI1_THETN ABC-type multidrug/protein/lipid transport... 469 e-130 >Q97FI3.1 Q97FI3_CLOAB MDR-type ABC transporter (Membrane associated ATPase) Length = 576 Score = 633 bits (1633), Expect = e-179, Method: Compositional matrix adjust. Identities = 303/578 (52%), Positives = 424/578 (73%), Gaps = 2/578 (0%) Query: 1 MDFSVLLRFFKAHKFSYLTGFAFMFAASFIQTLFPRVLGSAVDLMKESGFAVRQVMFQVL 60 M+ ++LL FF +KF Y+ G F+F +S+IQTLFP+VLG+ +D++K++ F++ V +L Sbjct: 1 MNKNILLNFFYRNKFKYIIGLIFVFLSSYIQTLFPKVLGNTIDILKKNNFSMISVKKNIL 60 Query: 61 WMTLIAAAVFACTFLWRNIIIANARNLECYFREELVRHFLKLSPAFYNTRKTGDLIAYAI 120 ++ LIA F T++WRN+II R LECY RE+L F +LSP FYN K G+LIAYAI Sbjct: 61 YIVLIAFFTFLLTYIWRNLIIGTGRTLECYLREKLFNKFQELSPEFYNNEKVGNLIAYAI 120 Query: 121 NDISAVRMTFGPATAMSFNGIVICFSSVYFMFATVDARLTLITLAPLPFIILLMLFTGRK 180 NDISAVR+TFGP+ AM+ NG+ +C SS+Y M ++ +LTL+ LAP+PFI+++M+ R Sbjct: 121 NDISAVRITFGPSIAMTVNGLTVCLSSIYSMIFSISLKLTLLCLAPIPFIVIIMIKISRL 180 Query: 181 VQTRFRIVQNQFGAVSDRVQENISGIRVIKAYVQERSEMERFSALSSRMKQANLDLIRVS 240 ++ RF VQ FG +SDRV ENI+GIRVIK+YV+E E+E F L+ M ANL ++RVS Sbjct: 181 IRARFTTVQESFGNISDRVNENINGIRVIKSYVEEEKEVENFEKLNDAMAIANLRMVRVS 240 Query: 241 AALPAMIEFGFAICFVLNLVFGSRMVLRGEISIGMFVAFNGYLSLIVNPIVSIGRIVTIF 300 + L +IE F++ F NL+ G MVL+G +S+G FVAFN YL++I+ P++SIGRI+ IF Sbjct: 241 STLSPIIELCFSLSFCANLIIGGNMVLKGTVSLGDFVAFNTYLAMIMAPVMSIGRILVIF 300 Query: 301 QRGMASLGRLHDILRIQPDIQDLPQAADIQPEGPVELRDLTFHYDGTGTPALKDISLVLP 360 QRGMASL RL+ I + DI D ++ +I +G +E+R+L+F Y T LK+I+L + Sbjct: 301 QRGMASLKRLNKIFSTKKDILDGEKSINIPLKGNIEIRNLSFKYKDTDIKTLKNINLSIK 360 Query: 361 KGHTLGIIGHTGSGKSTLASLLFRFFNVEPGRILLNGRXXXXNGYTLEALRGGLGYVPQD 420 KG +GIIG TGSGKSTL +LL + +NVE G I +GR N YTL +R +GYVPQD Sbjct: 361 KGELIGIIGKTGSGKSTLVNLLLKLYNVENGSIAFDGR--DINDYTLACIRNNIGYVPQD 418 Query: 421 TFIFAASVRENIVFFKDGYSEEEVREAARLSMIADSIGGLPEGYDTILGERGVNLSGGQK 480 F+F++++++NI FFKD Y + V +AA++S I D+I +G++T+LGERG+NLSGGQK Sbjct: 419 NFLFSSTIKDNIKFFKDVYDDAAVEKAAKISCIYDTILKFKDGFNTVLGERGINLSGGQK 478 Query: 481 QRLAIARALIRDPAILILDDALSAVDAVTEGLILERLRQTRQGKTNILISHRVSAVMEAD 540 QR++IARA+I+DP ILILDDALSAVD +TE I+E L+ R KT+I+I+HR+SAV AD Sbjct: 479 QRVSIARAVIKDPPILILDDALSAVDTITETNIIENLKLFRNEKTSIIIAHRLSAVKNAD 538 Query: 541 EIIVLDKGMIVERGTHAQLLKEGGLYYDIYTEQHEDGQ 578 +IIVL+KG I E G+H +LL +GG+YYDIY EQ+ED + Sbjct: 539 KIIVLNKGEIAEIGSHKELLAKGGIYYDIYKEQYEDKK 576 >B0K4H9.1 B0K4H9_THEPX ABC transporter related Length = 582 Score = 491 bits (1264), Expect = e-136, Method: Compositional matrix adjust. Identities = 258/580 (44%), Positives = 368/580 (63%), Gaps = 11/580 (1%) Query: 3 FSVLLRFFKAHKFSYLTGFAFMFAASFIQTLFPRVLGSAVDLMKESGFAVRQVMFQVLWM 62 F+ ++ F K HK+ Y+ G F+ A +Q + P +LGS DL K + ++ W+ Sbjct: 4 FATVIPFIKKHKWDYIIGIIFLLAVDLLQMIVPHLLGSVTDLFKSKDLTPKVLLTYSFWI 63 Query: 63 TLIAAAVFACTFLWRNIIIANARNLECYFREELVRHFLKLSPAFYNTRKTGDLIAYAIND 122 IA VFA F+WR I+ +R LE RE+L FL+LSP +YN KTGDL+A+A ND Sbjct: 64 IGIAILVFAFRFIWRMKIMGMSRLLEKELREQLFAKFLELSPQYYNEHKTGDLMAHATND 123 Query: 123 ISAVRMTFGPATAMSFNGIVICFSSVYFMFATVDARLTLITLAPLPFIILLMLFTGRKVQ 182 I+AVRM GP +S + + S + M T+D +LT++ L PLP I L++ G+ + Sbjct: 124 INAVRMAVGPGIILSVDASFLGISIILIMVFTIDPKLTILALLPLPVIALVVSRFGKVIH 183 Query: 183 TRFRIVQNQFGAVSDRVQENISGIRVIKAYVQERSEMERFSALSSRMKQANLDLIRVSAA 242 +RF VQ F +++D+VQE+ISGIRVIKA+VQE+ E+E F + R +AN+D+I++ Sbjct: 184 SRFLKVQEAFASLTDKVQESISGIRVIKAFVQEKEEIENFRGENLRNFKANMDMIKIWGL 243 Query: 243 LPAMIEFGFAICFVLNLVFGSRMVLRGEISIGMFVAFNGYLSLIVNPIVSIGRIVTIFQR 302 ++F A+ F + L++G V++G I++G FVAF YL +++ P+++ G ++ IFQR Sbjct: 244 FDPTVQFLAALSFTIALLYGGIQVIKGIITLGDFVAFTSYLGMLIWPMMAFGWVINIFQR 303 Query: 303 GMASLGRLHDILRIQPDIQDLPQAADIQP-EGPVELRDLTFHYDGTGTPALKDISLVLPK 361 G AS+ RL+ I P+I D +I +G +E+++LTF Y P LK+I++ LPK Sbjct: 304 GSASMERLNIIFSEVPEITDNYADPNITVIDGNIEIKNLTFSYKKGLPPVLKNINISLPK 363 Query: 362 GHTLGIIGHTGSGKSTLASLLFRFFNVEPGRILLNGRXXXXNGYTLEALRGGLGYVPQDT 421 G TL IIG TGSGKSTL +LL R + V I ++G N L+ LR +G+VPQD Sbjct: 364 GKTLAIIGKTGSGKSTLVNLLARLYKVPQDTIFIDGH--DINEIPLKVLRENIGFVPQDN 421 Query: 422 FIFAASVRENIVFFKDGYSEEEVREAARLSMIAD---SIGGLPEGYDTILGERGVNLSGG 478 FIF+ ++ NI F +EE + + + + IAD I P+ Y TI+GERGV LSGG Sbjct: 422 FIFSDTIANNIAFV----NEEPLEKIQQFATIADVHKDIMDFPQQYQTIVGERGVTLSGG 477 Query: 479 QKQRLAIARALIRDPAILILDDALSAVDAVTEGLILERLRQTRQGKTNILISHRVSAVME 538 QKQR+AIARALI++P ILILDD+LSAVD TE IL LR+ + +T I++SHR+S + Sbjct: 478 QKQRIAIARALIKEPKILILDDSLSAVDTNTEETILSNLRKYMKNRTTIIVSHRISTIKN 537 Query: 539 ADEIIVLDKGMIVERGTHAQLLKEGGLYYDIYTEQH-EDG 577 ADEIIVLD G IVERGTH +L+K GLY IY +Q ED Sbjct: 538 ADEIIVLDNGEIVERGTHEELIKLKGLYNSIYEKQQLEDA 577 >B0KAL3.1 B0KAL3_THEP3 ABC transporter related Length = 582 Score = 489 bits (1259), Expect = e-136, Method: Compositional matrix adjust. Identities = 257/580 (44%), Positives = 368/580 (63%), Gaps = 11/580 (1%) Query: 3 FSVLLRFFKAHKFSYLTGFAFMFAASFIQTLFPRVLGSAVDLMKESGFAVRQVMFQVLWM 62 F+ ++ F K HK+ Y+ G F+ A +Q + P +LGS DL K + ++ W+ Sbjct: 4 FATVIPFIKKHKWDYIIGIIFLLAVDLLQMIVPHLLGSVTDLFKSKDLTPKVLLTYSFWI 63 Query: 63 TLIAAAVFACTFLWRNIIIANARNLECYFREELVRHFLKLSPAFYNTRKTGDLIAYAIND 122 IA VFA F+WR I+ +R LE RE+L FL+LSP +YN KTGDL+A+A ND Sbjct: 64 IGIAILVFAFRFIWRMKIMGMSRLLEKELREQLFAKFLELSPQYYNEHKTGDLMAHATND 123 Query: 123 ISAVRMTFGPATAMSFNGIVICFSSVYFMFATVDARLTLITLAPLPFIILLMLFTGRKVQ 182 I+AVRM GP +S + + S + M T+D +LT++ L PLP I L++ G+ + Sbjct: 124 INAVRMAVGPGIILSVDASFLGISIILIMVFTIDPKLTILALLPLPVIALVVSRFGKVIH 183 Query: 183 TRFRIVQNQFGAVSDRVQENISGIRVIKAYVQERSEMERFSALSSRMKQANLDLIRVSAA 242 +RF VQ F +++D+VQE+ISGIRVIKA+VQE+ E+E F + R +AN+D+I++ Sbjct: 184 SRFLKVQEAFASLTDKVQESISGIRVIKAFVQEKEEIENFRGENLRNFKANMDMIKIWGL 243 Query: 243 LPAMIEFGFAICFVLNLVFGSRMVLRGEISIGMFVAFNGYLSLIVNPIVSIGRIVTIFQR 302 ++F A+ F + L++G V++G I++G FVAF YL +++ P+++ G ++ IFQR Sbjct: 244 FDPTVQFLAALSFTIALLYGGIQVIKGIITLGDFVAFTSYLGMLIWPMMAFGWVINIFQR 303 Query: 303 GMASLGRLHDILRIQPDIQDLPQAADIQP-EGPVELRDLTFHYDGTGTPALKDISLVLPK 361 G AS+ RL+ I P+I D +I +G +++++LTF Y P LK+I++ LPK Sbjct: 304 GSASMERLNIIFSEVPEITDNYADPNITVIDGNIKIKNLTFSYKKGLPPVLKNINISLPK 363 Query: 362 GHTLGIIGHTGSGKSTLASLLFRFFNVEPGRILLNGRXXXXNGYTLEALRGGLGYVPQDT 421 G TL IIG TGSGKSTL +LL R + V I ++G N L+ LR +G+VPQD Sbjct: 364 GKTLAIIGKTGSGKSTLVNLLARLYKVPQDTIFIDGH--DINEIPLKVLRENIGFVPQDN 421 Query: 422 FIFAASVRENIVFFKDGYSEEEVREAARLSMIAD---SIGGLPEGYDTILGERGVNLSGG 478 FIF+ ++ NI F +EE + + + + IAD I P+ Y TI+GERGV LSGG Sbjct: 422 FIFSDTIANNIAFV----NEEPLEKIQQFATIADVHKDIMDFPQQYQTIVGERGVTLSGG 477 Query: 479 QKQRLAIARALIRDPAILILDDALSAVDAVTEGLILERLRQTRQGKTNILISHRVSAVME 538 QKQR+AIARALI++P ILILDD+LSAVD TE IL LR+ + +T I++SHR+S + Sbjct: 478 QKQRIAIARALIKEPKILILDDSLSAVDTNTEETILSNLRKYMKNRTTIIVSHRISTIKN 537 Query: 539 ADEIIVLDKGMIVERGTHAQLLKEGGLYYDIYTEQH-EDG 577 ADEIIVLD G IVERGTH +L+K GLY IY +Q ED Sbjct: 538 ADEIIVLDNGEIVERGTHEELIKLKGLYNSIYEKQQLEDA 577 >B7R6K1.1 B7R6K1_9THEO ABC transporter, ATP-binding protein Length = 582 Score = 472 bits (1214), Expect = e-131, Method: Compositional matrix adjust. Identities = 250/573 (43%), Positives = 366/573 (63%), Gaps = 4/573 (0%) Query: 3 FSVLLRFFKAHKFSYLTGFAFMFAASFIQTLFPRVLGSAVDLMKESGFAVRQVMFQVLWM 62 F+ ++ F K HK+ Y+ G F+ +Q + P +LGS DL K + ++ LW+ Sbjct: 4 FATVIPFIKKHKWDYIIGIIFLLGVDLLQMIIPHLLGSVTDLFKSKDLTPKILLNYSLWI 63 Query: 63 TLIAAAVFACTFLWRNIIIANARNLECYFREELVRHFLKLSPAFYNTRKTGDLIAYAIND 122 I+ VFA F+WR I+ +R LE REEL L LSP +Y+ KTGDL+A+A ND Sbjct: 64 VGISLLVFAFRFVWRIKIMGMSRLLEKDLREELFSKLLTLSPQYYHEHKTGDLMAHATND 123 Query: 123 ISAVRMTFGPATAMSFNGIVICFSSVYFMFATVDARLTLITLAPLPFIILLMLFTGRKVQ 182 I+A+RM GP MS + + + + M T++ +LTL L PLP + L++ G+ + Sbjct: 124 INAIRMAAGPGIIMSIDASFLSITIILIMIFTINFKLTLFALLPLPVLALVVNRFGKIIH 183 Query: 183 TRFRIVQNQFGAVSDRVQENISGIRVIKAYVQERSEMERFSALSSRMKQANLDLIRVSAA 242 RF VQ F +++D+VQE+ISGIRVIKA+VQE+ E+E F + R AN+++I++ Sbjct: 184 ARFTKVQEAFASLTDKVQESISGIRVIKAFVQEKEEIENFRQENFRNFLANMNMIKIWGL 243 Query: 243 LPAMIEFGFAICFVLNLVFGSRMVLRGEISIGMFVAFNGYLSLIVNPIVSIGRIVTIFQR 302 ++F A+ F + L++G V+RG IS+G FVAF YL +++ P+++ G ++ IFQR Sbjct: 244 FDPAVQFLAALSFTIALLYGGTQVIRGVISLGEFVAFTAYLGMLIWPMMAFGWVINIFQR 303 Query: 303 GMASLGRLHDILRIQPDIQDLPQAADIQP-EGPVELRDLTFHYDGTGTPALKDISLVLPK 361 G AS+ R++ IL P+I D +I +G +E+++LTF Y P LK+I+L +P+ Sbjct: 304 GAASMERINVILNEVPEITDKFADPNITTIKGDIEIKNLTFSYKKDLPPVLKNINLKIPR 363 Query: 362 GHTLGIIGHTGSGKSTLASLLFRFFNVEPGRILLNGRXXXXNGYTLEALRGGLGYVPQDT 421 G TL IIG TGSGKSTL +L+ R + V +I ++G N L+ LR +G+VPQD Sbjct: 364 GKTLAIIGKTGSGKSTLVNLIARLYTVPCDKIFIDGH--DINEIPLKVLRENIGFVPQDN 421 Query: 422 FIFAASVRENIVFFKDGYSEEEVREAARLSMIADSIGGLPEGYDTILGERGVNLSGGQKQ 481 FIF+ ++ NI F K+ E++++ A ++ + I P+ YDT++GERGV LSGGQKQ Sbjct: 422 FIFSDTIANNIAFTKEE-PLEKIQKFAEMADVHKDIVEFPQQYDTVVGERGVTLSGGQKQ 480 Query: 482 RLAIARALIRDPAILILDDALSAVDAVTEGLILERLRQTRQGKTNILISHRVSAVMEADE 541 R+AIARALI+DP ILILDD+LSAVD TE IL L++ + +T I++SHR+S + ADE Sbjct: 481 RIAIARALIKDPKILILDDSLSAVDTNTEERILNNLKEFMKDRTTIIVSHRISTIKNADE 540 Query: 542 IIVLDKGMIVERGTHAQLLKEGGLYYDIYTEQH 574 IIVLD+G IVERGTH +LL GLYY IY +Q Sbjct: 541 IIVLDEGEIVERGTHEELLNLKGLYYSIYEKQQ 573 >Q8RBI1.1 Q8RBI1_THETN ABC-type multidrug/protein/lipid transport system, ATPase component Length = 582 Score = 469 bits (1208), Expect = e-130, Method: Compositional matrix adjust. Identities = 249/573 (43%), Positives = 366/573 (63%), Gaps = 4/573 (0%) Query: 3 FSVLLRFFKAHKFSYLTGFAFMFAASFIQTLFPRVLGSAVDLMKESGFAVRQVMFQVLWM 62 F+ ++ F K HK+ Y+ G F+ +Q + P +LGS DL K + ++ LW+ Sbjct: 4 FTTVIPFIKRHKWDYIIGIIFLLGVDLLQMIIPHLLGSVTDLFKSKDLTPKILLNYSLWI 63 Query: 63 TLIAAAVFACTFLWRNIIIANARNLECYFREELVRHFLKLSPAFYNTRKTGDLIAYAIND 122 I+ VFA F+WR I+ +R LE RE+L L LSP +Y+ KTGDL+A+A ND Sbjct: 64 IGISLLVFAFRFIWRIKIMGMSRLLEKDLREDLFSKLLTLSPQYYHEHKTGDLMAHATND 123 Query: 123 ISAVRMTFGPATAMSFNGIVICFSSVYFMFATVDARLTLITLAPLPFIILLMLFTGRKVQ 182 I+A+RM GP MS + + + + M T++ +LTL L PLP + L++ G+ + Sbjct: 124 INAIRMAAGPGIIMSIDASFLSITIILIMIFTINFKLTLFALLPLPVLALVVNRFGKIIH 183 Query: 183 TRFRIVQNQFGAVSDRVQENISGIRVIKAYVQERSEMERFSALSSRMKQANLDLIRVSAA 242 RF VQ F +++D+VQE+ISGIRVIKA+VQE+ E+E F + R AN+++I++ Sbjct: 184 ARFTKVQEAFASLTDKVQESISGIRVIKAFVQEKEEIENFRQENFRNFLANMNMIKIWGL 243 Query: 243 LPAMIEFGFAICFVLNLVFGSRMVLRGEISIGMFVAFNGYLSLIVNPIVSIGRIVTIFQR 302 ++F A+ F + L++G V+RG IS+G FVAF YL +++ P+++ G ++ IFQR Sbjct: 244 FDPAVQFLAALSFTIALLYGGTQVIRGVISLGEFVAFTAYLGMLIWPMMAFGWVINIFQR 303 Query: 303 GMASLGRLHDILRIQPDIQDLPQAADIQP-EGPVELRDLTFHYDGTGTPALKDISLVLPK 361 G AS+ R++ IL P+I D +I +G +E+++LTF Y P LK+I+L +P+ Sbjct: 304 GAASMERINVILNEVPEITDKFADPNITTIKGDIEIKNLTFSYKKDLPPVLKNINLKIPR 363 Query: 362 GHTLGIIGHTGSGKSTLASLLFRFFNVEPGRILLNGRXXXXNGYTLEALRGGLGYVPQDT 421 G TL IIG TGSGKSTL +L+ R + V +I ++G N L+ LR +G+VPQD Sbjct: 364 GKTLAIIGKTGSGKSTLVNLIARLYTVPCDKIFIDGH--DINEIPLKVLRENIGFVPQDN 421 Query: 422 FIFAASVRENIVFFKDGYSEEEVREAARLSMIADSIGGLPEGYDTILGERGVNLSGGQKQ 481 FIF+ ++ NI F K+ E++++ A ++ + I P+ YDT++GERGV LSGGQKQ Sbjct: 422 FIFSDTIANNIAFTKEE-PLEKIQKFAEMADVHKDIVEFPQQYDTVVGERGVTLSGGQKQ 480 Query: 482 RLAIARALIRDPAILILDDALSAVDAVTEGLILERLRQTRQGKTNILISHRVSAVMEADE 541 R+AIARALI+DP ILILDD+LSAVD TE IL L++ + +T I++SHR+S + ADE Sbjct: 481 RIAIARALIKDPKILILDDSLSAVDTNTEERILNNLKEFMKDRTTIIVSHRISTIKNADE 540 Query: 542 IIVLDKGMIVERGTHAQLLKEGGLYYDIYTEQH 574 IIVLD+G IVERGTH +LL GLYY IY +Q Sbjct: 541 IIVLDEGEIVERGTHEELLNLKGLYYSIYEKQQ 573 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.327 0.142 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,194,865,574 Number of extensions: 130017787 Number of successful extensions: 761753 Number of sequences better than 1.0e-05: 79589 Number of HSP's gapped: 663711 Number of HSP's successfully gapped: 86287 Length of query: 585 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 444 Effective length of database: 1,732,333,088 Effective search space: 769155891072 Effective search space used: 769155891072 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 134 (56.2 bits)