BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0290.0013.p (535 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DHH8.1 B1DHH8_9BACL Two component transcriptional regulator, A... 394 e-107 B1DGI8.1 B1DGI8_9BACL Two component transcriptional regulator, A... 378 e-103 B1D8T6.1 B1D8T6_9BACL Two component transcriptional regulator, A... 375 e-102 B3KD31.1 B3KD31_9BACI Response regulator receiver 369 e-100 B1DAG4.1 B1DAG4_9BACL Two component transcriptional regulator, A... 350 2e-94 >B1DHH8.1 B1DHH8_9BACL Two component transcriptional regulator, AraC family Length = 542 Score = 394 bits (1011), Expect = e-107, Method: Compositional matrix adjust. Identities = 204/539 (37%), Positives = 329/539 (61%), Gaps = 10/539 (1%) Query: 1 MHQILLVDDEPYVVDDLSISLPWAELGFEQVHKAYSGYEALELLQRHPIDIVVTDINMPE 60 M Q+LLVDDE VV+ L+ ++PW E G VH+A SG AL++++ H IDIV+TDI MP Sbjct: 1 MLQLLLVDDERSVVETLAETIPWEECGISVVHEALSGPIALQIMEDHAIDIVITDIKMPG 60 Query: 61 ISGIELIAAIRSRWKHIRVVMLTGYAEFEYARKAIEEQASAYLLKPIANDQLIAVIVKLR 120 +SGIELI AI S+W H+R ++LTGYA+F+YA++AI + YLLKP++++ LI + ++ Sbjct: 61 MSGIELITAINSKWPHVRTILLTGYADFDYAKQAIAQNTFDYLLKPVSDEDLIDSVERVV 120 Query: 121 EELRSEWEAWSSYQRTMQTFXXXXXXXXXXXXXXXXXXXKMPKAQLEERLAQFDLPLSTA 180 ++++ +WE +SY++T+ T ++ L ++LA +LP + Sbjct: 121 KQIKEKWEEVASYRKTLYTLNENLPLLRANTLNELLRGSN--QSALADKLALLELPFAED 178 Query: 181 LPVCLAVVRPEEFFRRQDMHSMLLFEYAIINIAQELFQNRFRIWSCKDVHDYLVFLLQPR 240 VC+ ++R EE F L EYAI NI E+ QN + IW +D HDY+V +++P+ Sbjct: 179 DGVCMMLIRMEERFAEMPGQDSALMEYAICNITSEIMQNDYHIWHARDAHDYIVLIVKPK 238 Query: 241 DDIEAGGNPGDDVAQAAYQLQNHVGTLIGGGLSVVTTGWGGFPDQVYTLYQSAISAIRQH 300 + A + + A Q+Q +V + G +SV+ G G FP QV +Y+ A++++R+ Sbjct: 239 NTAVADMEARSLLERYAAQIQTNVQNYLKGAISVLVGGQGTFPGQVKEIYEHAVTSMRRK 298 Query: 301 IGSETGIYLDASDNSGSQPVEILQPLYEPPLFFHMFEANNWQGIEDKLNAIAS---ELGR 357 +G G+++ + S P+ + LYEPP + +A + +E K+ I E G Sbjct: 299 MGHGKGLFVTTQEALDSSPMNTVWSLYEPPTLISLLDAGRFDDVETKIRHIFRDMLETGG 358 Query: 358 NPDRSLEHIHEARLHLETAFYYFAHKNNKMLSEIVGNPLLE--QAP-FQTPDMLRDWALE 414 D S E + EA L AF Y HKN K+LS ++ L+ AP + T L +W++ Sbjct: 359 EQDMS-EQLIEAYHVLAGAFSYIIHKNGKLLSSVLSPEALKFFHAPAYTTAAQLMEWSIR 417 Query: 415 VIVLLREHFESERRDSRTVLIRSIHEYINSNLHY-VSLQAIADHVQMHPVYLSKMYKLET 473 ++ +RE + E +D+ + ++R++ +I++NL VSL AIADHV +HPVYLSK+YK ET Sbjct: 418 ILQGIREDADQELKDNHSTIVRAVRSFIDANLAKDVSLPAIADHVHLHPVYLSKIYKAET 477 Query: 474 GKRISDYISQAKMEKAAYLLIHTPLKIYEVSAELGYSNAHYFIKLFKEYSGMTPHEFRD 532 G+ +++Y+ + +MEKAA+LL TP K++E+S +GY+N YFI++FK++ +TP E+RD Sbjct: 478 GEPLTEYVYRLRMEKAAFLLRTTPSKVFEISEIVGYNNTAYFIRVFKKFFDVTPQEYRD 536 >B1DGI8.1 B1DGI8_9BACL Two component transcriptional regulator, AraC family Length = 539 Score = 378 bits (971), Expect = e-103, Method: Compositional matrix adjust. Identities = 205/538 (38%), Positives = 312/538 (57%), Gaps = 9/538 (1%) Query: 1 MHQILLVDDEPYVVDDLSISLPWAELGFEQVHKAYSGYEALELLQRHPIDIVVTDINMPE 60 M Q+L+VDDE +VVD L+ ++ W +G +QV+KAYSG EALE L + IDIV+TDI MP Sbjct: 1 MAQLLIVDDEAHVVDRLATTVDWESVGIDQVYKAYSGQEALEQLHQFSIDIVITDIRMPG 60 Query: 61 ISGIELIAAIRSRWKHIRVVMLTGYAEFEYARKAIEEQASAYLLKPIANDQLIAVIVKLR 120 +SG++LI+ I+ +W + ++L+GY+EF YA++A++ Q YLLKP+ L++ + ++ Sbjct: 61 MSGLQLISEIKRQWPKTKSILLSGYSEFNYAKQAMQFQTEDYLLKPVKTSDLLSTVERVL 120 Query: 121 EELRSEWEAWSSYQRTMQTFXXXXXXXXXXXXXXXXXXXKMPKAQLEERLAQFDLPLSTA 180 +L+ EWE S QR T K L E++ + +L Sbjct: 121 RKLKQEWEEVISAQRITYTLKEHLPLLRANLLQELLQGKLWSKQTLREKMTRLELGDRDW 180 Query: 181 LPVCLAVVRPEEFFRRQDMHSMLLFEYAIINIAQELFQNRFRIWSCKDVHDYLVFLLQPR 240 L VR ++ F + EYA+ N+A+ELF R+ +W KD HDYLVFLL + Sbjct: 181 QRFSLMAVRLDDRFGEFTEEDLSWKEYAVANMAEELFGGRYSLWHAKDAHDYLVFLLTLK 240 Query: 241 DDIEAGGNPGDDVAQAAYQLQNHVGTLIGGGLSVVTTGWGGFPDQVYTLYQSAISAIRQH 300 D+ E G +PG + + A LQ+ VG + G +SV+ + G FP+ V Y +I+A R Sbjct: 241 DEAE-GDDPG-WLERTASVLQSAVGVYLKGKVSVMVSSAGAFPEDVPGFYNRSITAFRNR 298 Query: 301 IGSETGIYLDASDNSGSQPVEI--LQPLYEPPLFFHMFEANNWQGIEDKLNAIASELGRN 358 IG E ++ + S+P I L LYEPP H+ EA W+ +E++ I + + Sbjct: 299 IGQEPEQFMRLEEKE-SEPAAIRSLDCLYEPPALIHLLEAARWEAVEERYKRIFTGVESG 357 Query: 359 PDRSLEHIHEARLHLETAFYYFAHKNNKMLSEIVG---NPLLEQAPFQTPDMLRDWALEV 415 S EH+ E + +A+ Y AHKN ++L+E +G N + P +T LR+WA Sbjct: 358 ETVSEEHLLEIYFTVASAYAYIAHKNGRLLNETLGTDYNRMATGMPLRTVQHLREWAFRT 417 Query: 416 IVLLREHFESERRDSRTVLIRSIHEYINSNLHY-VSLQAIADHVQMHPVYLSKMYKLETG 474 + L+E E +D+R LI I +I+ N+ +SLQ++AD+V++HPVY+SK+YKLETG Sbjct: 418 LKALQEDMAKETKDNRHSLIERIRSFIDDNVTGDISLQSVADYVKLHPVYVSKVYKLETG 477 Query: 475 KRISDYISQAKMEKAAYLLIHTPLKIYEVSAELGYSNAHYFIKLFKEYSGMTPHEFRD 532 + +SDYI + KME+A +L + K+Y ++A LGY H FI FK+ GMTP E+RD Sbjct: 478 ENLSDYIQRVKMEEAQSMLRRSDEKVYVIAARLGYQRPHSFISAFKKTFGMTPQEYRD 535 >B1D8T6.1 B1D8T6_9BACL Two component transcriptional regulator, AraC family Length = 541 Score = 375 bits (962), Expect = e-102, Method: Compositional matrix adjust. Identities = 200/538 (37%), Positives = 314/538 (58%), Gaps = 5/538 (0%) Query: 1 MHQILLVDDEPYVVDDLSISLPWAELGFEQVHKAYSGYEALELLQRHPIDIVVTDINMPE 60 M Q+L+VDD+ + DDL+ LPW E G + VHKAYSG EA+ LL H ID+V+TDI MP Sbjct: 1 MRQLLIVDDQSILADDLADMLPWEEAGVDVVHKAYSGPEAIGLLHEHAIDVVITDIRMPG 60 Query: 61 ISGIELIAAIRSRWKHIRVVMLTGYAEFEYARKAIEEQASAYLLKPIANDQLIAVIVKLR 120 ++G+ELI I+ WKH + ++L+GY++FEY ++A++ ++S YLLKP ++D+L+ + + Sbjct: 61 MTGLELIQEIKQNWKHTKCILLSGYSDFEYTKQALKLKSSDYLLKPASDDELLTSVRRAI 120 Query: 121 EELRSEWEAWSSYQRTMQTFXXXXXXXXXXXXXXXXXXXK-MPKAQLEERLAQFDLPLST 179 +EL EW SS QR M + + + +L ++LA + +P Sbjct: 121 KELEQEWLEISSMQRAMYSLREQLPKLREYLLLDMLSGKQSLSPQRLSKKLATYTVPFQE 180 Query: 180 ALPVCLAVVRPEEFFR-RQDMHSMLLFEYAIINIAQELFQNRFRIWSCKDVHDYLVFLLQ 238 + ++R ++ R D S L +YA+ NIA+E+F ++ +W CKD + ++V LL+ Sbjct: 181 NDDFHVMLLRIDDEDRLYDDGESEALIDYALANIAEEVFGDQLDMWHCKDSNGFIVCLLK 240 Query: 239 PRDDIEAGGNPGDDVAQAAYQLQNHVGTLIGGGLSVVTTGWGGFPDQVYTLYQSAISAIR 298 + + + + A+QLQ+ V + + G+S++T+ G FP V LYQ++I+ R Sbjct: 241 AKAGSTITSDLDEWIESHAFQLQHVVKSYLKVGISILTSKRGSFPQDVGPLYQTSITNFR 300 Query: 299 QHIGSETGIYLDASDNSGSQPVEILQPLYEPPLFFHMFEANNWQGIEDKLNAIASELGRN 358 Q IGSE +++ + ++L LY PP M E W +KL AI E+ Sbjct: 301 QFIGSEQELFVSLAKEPTRGTPQLLGELYRPPSVLQMLELGQWDAAGEKLEAIFREIEEE 360 Query: 359 PDRSLEHIHEARLHLETAFYYFAHKNNKMLSEIVGN---PLLEQAPFQTPDMLRDWALEV 415 S EH+ EA + AHKN K LS+++G+ +P T D LR W Sbjct: 361 WRGSQEHVLEAYFSIAATLAALAHKNKKWLSDMIGDDFHAFANGSPIHTVDDLRTWTART 420 Query: 416 IVLLREHFESERRDSRTVLIRSIHEYINSNLHYVSLQAIADHVQMHPVYLSKMYKLETGK 475 I R+ SE +DSR+ +IR + E+I+++L SL +I+ HV ++P YLSK+YK ETG+ Sbjct: 421 IDSYRKSVNSEDKDSRSSIIRKVQEFIHNHLEQASLHSISTHVYLNPSYLSKIYKTETGE 480 Query: 476 RISDYISQAKMEKAAYLLIHTPLKIYEVSAELGYSNAHYFIKLFKEYSGMTPHEFRDR 533 IS+Y+ +A+MEK+A LL T KIYE+S LGY YFI+LFK++ G+TP E+R++ Sbjct: 481 GISEYLLRARMEKSADLLAQTDEKIYEISVMLGYQKPSYFIQLFKKHFGITPQEYRNK 538 >B3KD31.1 B3KD31_9BACI Response regulator receiver Length = 586 Score = 369 bits (948), Expect = e-100, Method: Compositional matrix adjust. Identities = 202/581 (34%), Positives = 322/581 (55%), Gaps = 51/581 (8%) Query: 1 MHQILLVDDEPYVVDDLSISLPWAELGFEQVHKAYSGYEALELLQRHPIDIVVTDINMPE 60 M+ +L+VDDE VV+ L+ ++PW ++G ++V KAYS +EALE+LQ P+DI+++DI MP Sbjct: 1 MYTLLIVDDEASVVEGLAHTIPWQKIGIDEVRKAYSAFEALEILQTQPVDIMISDITMPR 60 Query: 61 ISGIELIAAIRSRWKHIRVVMLTGYAEFEYARKAIEEQASAYLLKPIANDQLIAVIVKLR 120 ++G+EL+ +S+WKHI+ ++L+GYA+F YA++AI YLLKP++++ ++ + Sbjct: 61 MNGLELVEITKSKWKHIKTILLSGYADFAYAKEAITLGTYEYLLKPVSDEVVLEKVGGAV 120 Query: 121 EELRSEWEAWSSYQRTMQTFXXXXXXXXXXXXXXXXXXXKMPKAQLEERLAQFDLPLSTA 180 E LR E E+ +Y R +Q F K PK E+L ++ + Sbjct: 121 ESLRQERESSETYNRAVQAFRANLPQIRGEFLNQLLQGMKSPKNVWAEKLELLEMKSAIG 180 Query: 181 LPVCLAVVRPEEFFRRQDMHSMLLFEYAIINIAQELFQNRFRIWSCKDVHDYLVFLLQPR 240 L +VR E+ + + EYAI N+A E+F RFR+W C+D+H YLVF + Sbjct: 181 NQAALMLVRMEDRLTEMSPYDSSIMEYAIGNMADEIFGERFRLWRCRDIHGYLVFFV--F 238 Query: 241 DDI---------------------EAGGNPG------------------------DDVAQ 255 +DI ++ +P +++ Sbjct: 239 EDISKYKLSSTSSLISQEKLPLMKDSTTSPSGFDSSFSYSDDSAARVHPHEHTEENELKH 298 Query: 256 AAYQLQNHVGTLIGGGLSVVTTGWGGFPDQVYTLYQSAISAIRQHIGSETGIYLDASDNS 315 A QLQ +V + G +SV+ G FP+ V LYQ ++ A+R+HIGS + +++ A D Sbjct: 299 FAAQLQMNVSRYLKGTISVLIGKRGSFPEDVRKLYQDSLFALRRHIGSHSDMFVYAEDEE 358 Query: 316 GSQPVEILQPLYEPPLFFHMFEANNWQGIEDKLNAIASELGRNPDRSLEHIHEARLHLET 375 PV LQ YEPPL H+ E+ +W+ I++KL I EL +S EH+ EA + + Sbjct: 359 ELHPVRSLQKCYEPPLLHHLLESGSWKQIQEKLEQILKELSLAHSQSQEHVIEAFFFIYS 418 Query: 376 AFYYFAHKNNKMLSEIVGNPLLEQAPFQ---TPDMLRDWALEVIVLLREHFESERRDSRT 432 + +AHKN + L++IVG L + T L W +V+ LL E R R+ Sbjct: 419 SLSAYAHKNGRSLADIVGASLADVTGLSQCTTAATLGKWVGQVLPLLESSAEQATRSDRS 478 Query: 433 VLIRSIHEYINSNLHY-VSLQAIADHVQMHPVYLSKMYKLETGKRISDYISQAKMEKAAY 491 + + +I +L +SLQAIADH+ MHPV++S+++K+ETG +SDY+ + KME+AA Sbjct: 479 AAVSRMKRFIRDHLSQDISLQAIADHMYMHPVHVSRLFKMETGFNVSDYVLRLKMEQAAE 538 Query: 492 LLIHTPLKIYEVSAELGYSNAHYFIKLFKEYSGMTPHEFRD 532 LL LK +E++ +LGY N +YFI++FK+Y +TP E+R+ Sbjct: 539 LLADHSLKNFEIALKLGYHNPNYFIRVFKKYYSVTPQEYRN 579 >B1DAG4.1 B1DAG4_9BACL Two component transcriptional regulator, AraC family Length = 535 Score = 350 bits (899), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 197/534 (36%), Positives = 309/534 (57%), Gaps = 6/534 (1%) Query: 3 QILLVDDEPYVVDDLSISLPWAELGFEQVHKAYSGYEALELLQRHPIDIVVTDINMPEIS 62 Q+L+VDDE + V++LS+ PW LG E VH+AYS EAL+++ +PIDIV++D+ MPE++ Sbjct: 2 QLLIVDDEAHWVENLSMHKPWHTLGIEYVHRAYSAREALQIIGTNPIDIVISDVLMPEMT 61 Query: 63 GIELIAAIRSRWKHIRVVMLTGYAEFEYARKAIEEQASAYLLKPIANDQLIAVIVKLREE 122 GIELI IR + K I+ ++L+G+A+FEYA++A+ A YLLKP N++L+ ++ Sbjct: 62 GIELIERIREQDKRIKCIILSGHADFEYAKEALRHHAVDYLLKPPTNEELLGAAQTAIDQ 121 Query: 123 LRSEWEAWSSYQRTMQTFXXXXXXXXXXXXXXXXXXXKMPKAQLEERLAQFDLPLSTALP 182 L++EWE SS +RT ++ + + +L + LP + Sbjct: 122 LKAEWENVSSQERTQFALRENLPLLRGQLLLGAFRGERIAEEEWIRKLDMYGLPFRSG-S 180 Query: 183 VCLAVVRPEEFFRRQDMHSMLLFEYAIINIAQELFQNRFRIWSCKDVHDYLVFLLQPRDD 242 LA+VR E+ F + L EYAI+NIA+E+ Q +WS K+ H YL FLLQ ++ Sbjct: 181 CALALVRLEDEFGHYRGNGQHLVEYAIMNIAEEILQEFMGVWSVKEEHGYLAFLLQAKEH 240 Query: 243 IEAGGNPGDDVAQAAYQLQNHVGTLIGGGLSVVTTGWGGFPDQVYTLYQSAISAIRQHIG 302 A P + + A Q+Q V + G +SVV T FP+++ Y+ A+S RQ +G Sbjct: 241 -PAVDRPDILLEKLAMQIQAKVKQFLKGAVSVVVTDSFLFPEELPEQYRQAVSYFRQIVG 299 Query: 303 SETGIYLDASDNSGSQPVEILQPLYEPPLFFHMFEANNWQGIEDKLNAIASELGRNPDRS 362 E + + L ++ P ++ EA W+ EDKL A EL S Sbjct: 300 DEQEFVMKVDGTRKATAFGALDVIHGHPGLLNLAEAGRWEAAEDKLAAAFDELEDKGSES 359 Query: 363 LEHIHEARLHLETAFYYFAHKNNKMLSEIVG--NPLLEQA-PFQTPDMLRDWALEVIVLL 419 EH E + +AF + AH++ L++++G LL+ F + LR W+L + L Sbjct: 360 WEHCLEMGYTISSAFMHLAHRSGHTLADLIGPDMELLQSGEAFASIGKLRKWSLNALAKL 419 Query: 420 REHFESERRDSRTVLIRSIHEYINSNLHY-VSLQAIADHVQMHPVYLSKMYKLETGKRIS 478 RE + +++R+ ++ I +Y++ +LH VSL+A+AD+V +HP +LSK+YKLETG+ IS Sbjct: 420 REGTAHDAKNARSQYVQKIRDYVDKHLHLDVSLRALADYVNLHPTHLSKIYKLETGEGIS 479 Query: 479 DYISQAKMEKAAYLLIHTPLKIYEVSAELGYSNAHYFIKLFKEYSGMTPHEFRD 532 DY++ +ME+A +LL T KIYE+SA++GY + YFIK+FK +TP E+RD Sbjct: 480 DYVASVRMERACHLLKATDKKIYEISADIGYLDPAYFIKVFKRQFDVTPQEYRD 533 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.137 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,085,405,384 Number of extensions: 125536927 Number of successful extensions: 380922 Number of sequences better than 1.0e-05: 9008 Number of HSP's gapped: 393044 Number of HSP's successfully gapped: 9624 Length of query: 535 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 394 Effective length of database: 1,732,333,088 Effective search space: 682539236672 Effective search space used: 682539236672 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 134 (56.2 bits)