BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0284.0013.p (565 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DBI1.1 B1DBI1_9BACL Integral membrane sensor signal transducti... 302 5e-80 B3KA97.1 B3KA97_9BACI Histidine kinase internal region 271 1e-70 A9U806.1 A9U806_PHYPA Predicted protein 189 8e-46 C5EFW3.1 C5EFW3_9FIRM Histidine kinase internal region 160 3e-37 A6NTG2.1 A6NTG2_9BACE Putative uncharacterized protein 156 6e-36 >B1DBI1.1 B1DBI1_9BACL Integral membrane sensor signal transduction histidine kinase Length = 605 Score = 302 bits (774), Expect = 5e-80, Method: Compositional matrix adjust. Identities = 188/578 (32%), Positives = 312/578 (53%), Gaps = 23/578 (3%) Query: 2 LYITNAYSKLIIREHSLEKATQSLTIVQSQINVILEEMVSVSNFVHFDPEIKT---LLEE 58 + I N+ ++ + + E AT S+ +V IN + + M++ +N++ + ++K+ + Sbjct: 31 MLIYNSLTREAVERQAKENATDSMQLVNGSINNLFQGMLNTANYLQANADMKSSFIKMLN 90 Query: 59 AKTNPVAARTLTSRLEQ------VAGETADLRITLLGKDGHAYSDYSFYDFNPRQFIEKS 112 +P T TSR+ Q GE + IT++ +G +++YS + +P F ++S Sbjct: 91 TDLDPYEKFTATSRIMQQLETLTYIGEKS--YITIILTNGETFTNYSKDEMDPLTFQKES 148 Query: 113 WFSTLERLSPYGTLFLGAEANYLSSSESDKPFVFMTARALREGTATAPYAYLIVSRSEAS 172 WF+ L++L+ + ++ P+ AR LR +T Y Y+IV+ E Sbjct: 149 WFNNLKQLTGLQSYWVSTSPTIFPYDRISSPYQISVARTLR-FDSTRIYGYVIVTMMENK 207 Query: 173 IRERFASM--EEDVYLLDETETILSNRNQALIGSNF---NTLLPIDELVFPDIVEFKDEN 227 + S+ ++V L+D ILS+ + NF + D V I+ KDEN Sbjct: 208 FSKILGSLTGSQEVVLVDGDGKILSSPQLEQVNGNFEYSKQMAERDSRVASSII--KDEN 265 Query: 228 Q--LLLSLPLKYAKWRLVSVAPYEQLTERLNGINRTGILLQAVFAISFLFALTYLLRRFT 285 + LL + L + W LV+ PY+ ++ I L Q V I+FL L L+R+ T Sbjct: 266 KKLLLTTADLSFNDWHLVATEPYQDAIVNISSIFSRVFLFQIVSFIAFLVVLLLLMRQLT 325 Query: 286 RPVHVLGKVARRVESGDMMVRSNIRGTDEMGSLGFSFDKMLDRVQLMLEQVETEQELKRQ 345 +P+ LGKVA V+ G++ VRS+IRG DE+G LGF FD+MLDR++ M+ +V Q KR+ Sbjct: 326 KPLIKLGKVASSVQRGNLEVRSSIRGADEIGRLGFLFDQMLDRIKEMITEVSLTQARKRK 385 Query: 346 AEIAMLQAQINPHFLFNVLSSIRLKLLMKQDEENAFIVGXXXXXXXXXXXXHDEFVSVAY 405 AE+AMLQAQINPHFLFNVL+SIR+K++ D+++A ++ ++ + + Sbjct: 386 AELAMLQAQINPHFLFNVLNSIRMKVMRSGDQDSAKMIASLSKLLRMTISRDEDAILLHE 445 Query: 406 ELESAKQYMELMRFTMRYPTDSLVNVNMDLLLETLPRFILQPIIENAYKHGFAQGGGRII 465 E+E Y+ELM + LV+V++ +PRFILQP++ENA HGF Q G I Sbjct: 446 EIELLTHYVELMNLRQKEEAQLLVDVDVTSFDIRVPRFILQPLVENALIHGFNQSAGTIR 505 Query: 466 ISIEKIKSMLQIRVEDNGTGMDEDTLAALMQHIKQKDAEIDTLKIAGTHGSSPFQGIGLI 525 I+ E+ L++ VED+G GMDE+ L L + A + ++ G GIG+ Sbjct: 506 ITAERKDRFLELSVEDDGIGMDEEGLERLRARLMTAGAGAEEVQETGRSKGPGMSGIGVA 565 Query: 526 NVYQRLKLIYGDRFEMDIESIHGHRTTVQLVLPVKRIG 563 NV +R+++++GD F + ++S HG R + + +P++ G Sbjct: 566 NVAERMRIMFGDAFHITVDSDHGTR--IMMHIPIREEG 601 >B3KA97.1 B3KA97_9BACI Histidine kinase internal region Length = 603 Score = 271 bits (694), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 178/570 (31%), Positives = 298/570 (52%), Gaps = 19/570 (3%) Query: 2 LYITNAYSKLIIREHSLEKATQSLTIVQSQINVILEEMVSVSNFVHFDPEIKTLLEE--- 58 L + N+ +K +R+ ++ A+ +L +V+ + +L ++++N++ + + + ++ Sbjct: 33 LILYNSLTKEALRQQAVSNASDALQLVRGSVTNLLLSKINIANYIQMNSGLNSYFKQVVS 92 Query: 59 AKTNPVAARTLTSR---LEQ-----VAGETADLRITLLGKDGHAYSDYSFYDFNPRQFIE 110 +P R LE V GE + +T++ ++G Y +YS D+NP + + Sbjct: 93 GNEDPDPYRRFIESNRVLEHLDSLTVVGEKS--YVTVILENGSYYMNYSVSDYNPLDYRQ 150 Query: 111 KSWFSTLERLSPYGTLFLGAEANYLSSSESDKPFVFMTARALREGTATAPYAYLIVSRSE 170 + WF + L +L+ EA S + D P R LR + Y Y+IV+ E Sbjct: 151 RPWFGQISELQGLESLWTEPEATMFRSDQIDHPTQLSVVRTLRLPDSEI-YGYVIVTFME 209 Query: 171 ASIRERFASMEE--DVYLLDETETILSNRNQALIGSNFNTLLPIDELVFPDIVEFKDENQ 228 I F S+ E D+ LLD TI+S +Q+ IG+ F +D+ IV K E Q Sbjct: 210 DQISGIFNSLSEGNDMVLLDAKGTIVSGTHQSQIGTTFAYHDDLDQEKPYSIVSMKGEKQ 269 Query: 229 LLLSLPLKYAKWRLVSVAPYEQLTERLNGINRTGILLQAVFAISFLFALTYLLRRFTRPV 288 L++ + +A WRLV + PY+ +N I Q + FL L L+R FT+P+ Sbjct: 270 LMVHQDIPFAGWRLVLMQPYKDAIVNINSIFNRVFWFQMCSFLIFLLLLIGLVRAFTKPL 329 Query: 289 HVLGKVARRVESGDMMVRSNIRGTDEMGSLGFSFDKMLDRVQLMLEQVETEQELKRQAEI 348 LGKVA V+ G++ VRS++ G DE+G LG FD MLDR + M+ ++ Q KR+AE+ Sbjct: 330 VKLGKVATAVQRGNLEVRSHVHGNDEVGRLGHLFDDMLDRFKAMISEISENQARKRKAEL 389 Query: 349 AMLQAQINPHFLFNVLSSIRLKLLMKQDEENAFIVGXXXXXXXXXXXXHDEFVSVAYELE 408 MLQAQI+PHFLFNVL+SIR+K++ + D E+A ++G ++ +++ E++ Sbjct: 390 RMLQAQIHPHFLFNVLNSIRMKVMKRGDPESAKMIGSLSVLLRMTISREEDEIALHEEID 449 Query: 409 SAKQYMELMRFTMRYPTDSLVNVNMDLLLETLPRFILQPIIENAYKHGFAQGGGRIIISI 468 Y+ LM + +++ + L +PRF LQPI+ENA HG Q G I I+ Sbjct: 450 LISHYVALMNLRQKEEVRLELDIAPEAFLFKVPRFFLQPIVENALIHGLNQQAGTIRIAA 509 Query: 469 EKIKSMLQIRVEDNGTGMDEDTLAALMQHIKQKDAEIDTLKIAGTHGSSPFQGIGLINVY 528 L + V+D+G GMD ++ + I+ A T + A + GS F IGL NV Sbjct: 510 AMKGRHLVLAVKDDGIGMDAAIRESIARRIQGGSAGSSTQEEA-SGGS--FSHIGLQNVM 566 Query: 529 QRLKLIYGDRFEMDIESIHGHRTTVQLVLP 558 +R+ +++G+ F+ + S G T +++ +P Sbjct: 567 ERMSMVFGEAFQCHVYSEPGQGTVIEMYIP 596 >A9U806.1 A9U806_PHYPA Predicted protein Length = 292 Score = 189 bits (479), Expect = 8e-46, Method: Compositional matrix adjust. Identities = 110/280 (39%), Positives = 166/280 (59%), Gaps = 23/280 (8%) Query: 283 RFTRPVHVLGKVARRVESGDMMVRSNIRGTDEMGSLGFSFDKMLDRVQLMLEQVETEQEL 342 ++T+PV L + A +VE G + RS +RG E+G LG +FD+MLDR+ M+ Q+E EQ Sbjct: 26 QWTKPVIRLARTASKVEKGFLDERSGVRGRHEVGFLGLAFDRMLDRISDMIVQIEEEQTR 85 Query: 343 KRQAEIAMLQAQINPHFLFNVLSSIRLKLLMKQDEENAFIVGXXXXXXXXXXXXHDEFVS 402 KR AE+ +LQAQINPHFLFN L+SIR+++++K +EE I+G ++E++ Sbjct: 86 KRMAELELLQAQINPHFLFNTLNSIRMQVILKGEEEIGGIIGSLSTLLRMTINRNNEYIP 145 Query: 403 VAYELESAKQYMELMRFTMRYPTDSLVNVNM--DLLLETLPRFILQPIIENAYKHGFAQG 460 + E+ + YM+LM F R+ + +NVN+ D LL ++PRF LQP++ENAY HG Q Sbjct: 146 LHEEVATVGHYMQLMNF--RHHEHAELNVNLASDTLLASIPRFTLQPLVENAYIHGLRQK 203 Query: 461 GGRIIISIEKIKSMLQIRVEDNGTGMDEDTLAALMQHIKQKDAEIDTLKIAGTHGSSPFQ 520 G I I+ K + L I++ D+G GM E+ L +P Sbjct: 204 SGEIAITSWKRQGTLFIQIHDDGIGMAEEVLERF-------------------RSGAPMS 244 Query: 521 GIGLINVYQRLKLIYGDRFEMDIESIHGHRTTVQLVLPVK 560 GIGL NV +RL+++YG RFEM++ S G + L +P++ Sbjct: 245 GIGLRNVKERLQIMYGIRFEMEMTSEPGEGLRIILKIPLQ 284 >C5EFW3.1 C5EFW3_9FIRM Histidine kinase internal region Length = 598 Score = 160 bits (405), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 127/475 (26%), Positives = 229/475 (48%), Gaps = 36/475 (7%) Query: 86 TLLGKDGHAYSDYSFYDFNPRQFIEKSWFSTLERLSPYGTLFLGAEANYLSSSESDKPFV 145 TL+G +G YS+ + + ++ F + W + + E +Y S + + Sbjct: 95 TLIGLNGFQYSNAAGFRYD--SFRQAPWMDAVLEANGQVVWIPTMEDSYAPFSSKN---I 149 Query: 146 FMTARALREGTATAPYAYLIVSRSEASIRERFASMEE---DVYLLDETETILSNRNQALI 202 ++ +R +R G P L + E S+ + +AS E +++D+ ++S++++ALI Sbjct: 150 YIMSRTIRTGHRLTPAGILSIMIDEDSLYKIYASSESADASYFIVDQEGAVISHKDKALI 209 Query: 203 GSNFNTLLPIDELVFPDIVEFKDENQLLLSLPLKYAK-----WRLVSVAPYEQL---TER 254 G+++++ +P+D + P + L Y K W LV P L + R Sbjct: 210 GTHWDSPVPLDSIRGPSGQSIARGGEAGLDNLYSYHKLNSSGWWLVESVPMSTLIHSSSR 269 Query: 255 LNGINRTGILLQAVFAISFLFALTYLLRRFTRPVHVLGKVARRVESGDMMVRSNIRGTDE 314 I ++ + + F +A + R +RP+ L + R+ GD+ +R DE Sbjct: 270 FLDIILIAAIICLISGLLFSYAFS---RYISRPIVELDRGMERIAQGDLQLRLPKTSQDE 326 Query: 315 MGSLGFSFDKMLDRVQLMLEQVETEQELKRQAEIAMLQAQINPHFLFNVLSSIRLKLLMK 374 +GSL F++M + +L ++ ++ KR+AEI LQAQINPHF++N L+SIR LM+ Sbjct: 327 LGSLIDGFNRMSRELDTLLSRIREQERHKRKAEIGFLQAQINPHFIYNTLNSIRCMTLMQ 386 Query: 375 QDEENAFIVGXXXXXXXXXXXXHDEFVSVAYELESAKQYMELMRFTMRYPTDSLVNVNMD 434 EE A ++ FV + EL S + Y+E+ + + ++++ + Sbjct: 387 NTEEAAKMLVSVISMMRTVLDTRKMFVPLDTELSSLENYLEIQKVIYSQKLEMELDISPN 446 Query: 435 LLLETLPRFILQPIIENAYKHGFAQGGGRIIISIEKIK------SMLQIRVEDNGTGMDE 488 + + +P+ ILQPI+EN+ HG + +I I + +L + V DNG M+ Sbjct: 447 VHMSMVPKLILQPIVENSVFHGIMRNNLNGVIHISAYREDADGVDLLHLVVTDNGR-MEP 505 Query: 489 DTLAALMQHIKQKDAEIDTLKIAGTHGSSPFQGIGLINVYQRLKLIYGDRFEMDI 543 TL L QH +++ E D+L G H IGL N+ +R+K IYG+ + + I Sbjct: 506 GTLKEL-QHRLEENQE-DSLS-NGNH-------IGLTNILRRIKQIYGEEYGLTI 550 >A6NTG2.1 A6NTG2_9BACE Putative uncharacterized protein Length = 576 Score = 156 bits (394), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 124/423 (29%), Positives = 196/423 (46%), Gaps = 27/423 (6%) Query: 146 FMTARALREGTATAPYAYLIVSRSEASIRERF---ASMEEDVYLLDETETILSNRNQALI 202 F A+ +R+ P +I++ SE S+ ++ S + + LLD T ++S +++ I Sbjct: 174 FQFAQLIRDHLTHEPLGIVILNISEVSLYSQYLELQSSDSNFVLLDGTGCVVSAKDKRRI 233 Query: 203 GSNFN-TLLPIDEL-VFPDIVEFKDENQLLLSLPLKYAKWRLVSVAPYEQLTERLNGINR 260 + TL +D D + Q+ LS + W +V LN + Sbjct: 234 AQPYAYTLEELDAFSAQTDPSSRVVDGQIYLSARIPGTDWHVVEELTAHSAFGTLNQLGA 293 Query: 261 TGILLQAVFAISFLFALTYLLRRFTRPVHVLGKVARRVESGDMMVRSNIRGTDEMGSLGF 320 +L + A L L Y R+ RP+ L RV G + +R DE G + Sbjct: 294 YTLLATVLCAALMLAVLLYAYRQIVRPIAQLQYSLGRVMDGHLDEHIEVRRQDEFGRIQM 353 Query: 321 SFDKMLDRVQLMLEQVETEQELKRQAEIAMLQAQINPHFLFNVLSSIRLKLLMKQDEENA 380 +F+ M+D++ +LE V+ E+ KR AE+ LQAQINPHF++N LSSIR L M + +E Sbjct: 354 AFNGMVDQLSTLLESVKREEREKRLAELDFLQAQINPHFIYNTLSSIRFLLEMDKVQEAG 413 Query: 381 FIVGXXXXXXXXXXXXHDEFVSVAYELESAKQYMELMRFTMRYPTDSLVNVNMD--LLLE 438 +V DEF+ + ELE + Y++L R +RYP + +D L Sbjct: 414 EMVFYFSKLLRQTLSRSDEFIPLGEELEMLECYVDLQR--LRYPETFRYSCEVDRSLWGN 471 Query: 439 TLPRFILQPIIENAYKHGFAQGGGRIIISIEKIKSMLQIRVEDNGTGMDEDTLAALMQHI 498 TLP+ +LQP++EN+ HG Q I + L ++VED+G G+ +D L +H+ Sbjct: 472 TLPKLLLQPVVENSIFHGVGQHQIHIRVRGWLEGDALILQVEDDGVGISKDKL----EHV 527 Query: 499 KQKDAEIDTLKIAGTHGSSPFQGIGLINVYQRLKLIYGDRFEMDIESIHGHRTTVQLVLP 558 KD +I+ +GL NV R++L YG + + I T V LP Sbjct: 528 MNKDLQINR--------------VGLKNVQDRIRLNYGPEYGLTIAGGPSGGTVVTFRLP 573 Query: 559 VKR 561 R Sbjct: 574 RTR 576 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.136 0.376 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,937,815,184 Number of extensions: 116962483 Number of successful extensions: 343456 Number of sequences better than 1.0e-05: 1769 Number of HSP's gapped: 340285 Number of HSP's successfully gapped: 1770 Length of query: 565 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 424 Effective length of database: 1,732,333,088 Effective search space: 734509229312 Effective search space used: 734509229312 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)