BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0280.0007.p (516 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KIK8.1 B3KIK8_9BACI YmdA/YtgF protein 783 0.0 B1DLE8.1 B1DLE8_9BACL RNA binding metal dependent phosphohydrolase 748 0.0 C0ZF12.1 C0ZF12_BREBN 2',3'-cyclic-nucleotide 2'-phosphodiestera... 681 0.0 Q9KAB2.1 CNPD_BACHD 2',3'-cyclic-nucleotide 2'-phosphodiesterase... 623 e-176 Q5WFX6.1 CNPD_BACSK 2',3'-cyclic-nucleotide 2'-phosphodiesterase... 619 e-175 >B3KIK8.1 B3KIK8_9BACI YmdA/YtgF protein Length = 513 Score = 783 bits (2022), Expect = 0.0, Method: Compositional matrix adjust. Identities = 404/513 (78%), Positives = 415/513 (80%) Query: 4 MHPAIWXXXXXXXXXXXXGFGYFIRXXXXXXXXXXXXXXXVVIXXXXXXXXXXXXXXXXX 63 M IW GFGYFIR + I Sbjct: 1 METWIWIIIVLAVAAIFFGFGYFIRKSLAEAKISSAEHAALQIVESAKKEAEALKKETVL 60 Query: 64 XXXDEVHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDKKMESLERKEEQVANKEKRID 123 DEVH DKK+ESLERKEEQVANKEKRI+ Sbjct: 61 EAKDEVHKIRAEAEKDTRERRNEIQRQERRLLQKEESLDKKIESLERKEEQVANKEKRIE 120 Query: 124 ETQQQIDVIYKNQVTELERISNLSIDDARSIILSNVEQEVRHETAQMIKEIEQQAKEEAD 183 ETQQQID IYK Q TELERISNL+++DARSIILSNVEQEVRHETAQMIKEIEQQAKEEAD Sbjct: 121 ETQQQIDAIYKKQTTELERISNLTMEDARSIILSNVEQEVRHETAQMIKEIEQQAKEEAD 180 Query: 184 KKAREIITLAIQRCAADHVAETTVSVVTLPNEEMKXXXXXXXXXXXXALETLTGIDLIID 243 KK+REIITLAIQRCAADHVAETTVSVVTLPNEEMK ALETLTGIDLIID Sbjct: 181 KKSREIITLAIQRCAADHVAETTVSVVTLPNEEMKGRIIGREGRNIRALETLTGIDLIID 240 Query: 244 DTPEAVILSGFDPIRREVARTALEKLVADGRIHPARIEEMVEKSRKEVDERIREYGEQAT 303 DTPEAVILSGFDPIRRE+ARTALEKLVADGRIHPARIEEMVEKSRKEVDERIREYGEQAT Sbjct: 241 DTPEAVILSGFDPIRREIARTALEKLVADGRIHPARIEEMVEKSRKEVDERIREYGEQAT 300 Query: 304 FEVGVHGLHPDLIKILGRLKFRTSYGQNVLKHSMEVAYLTGLMAGELGEDIVLAKRAGLL 363 FEVGVHGLHPDLIKILGRLKFRTSYGQNVLKHSMEVAYLTGLMAGELGEDIVLAKRAGLL Sbjct: 301 FEVGVHGLHPDLIKILGRLKFRTSYGQNVLKHSMEVAYLTGLMAGELGEDIVLAKRAGLL 360 Query: 364 HDIGKALDHEVEGSHVEIGVELAKKYKEHPVVINSIASHHGDCEATSVIAMLVGAADALS 423 HDIGKALDHEVEGSHVEIGVELAKKYKEHPVVINSIASHHGDCEATSVIAMLVGAADALS Sbjct: 361 HDIGKALDHEVEGSHVEIGVELAKKYKEHPVVINSIASHHGDCEATSVIAMLVGAADALS 420 Query: 424 AARPGARRETLETYIKRLEKLEEISESFEGVEKSYAIQAGREVRVMVQPEKIDDAEAFRL 483 AARPGARRETLETYI+RLEKLEEISESFEGVEKSYAIQAGREVRVMVQPEKIDDAEAFRL Sbjct: 421 AARPGARRETLETYIRRLEKLEEISESFEGVEKSYAIQAGREVRVMVQPEKIDDAEAFRL 480 Query: 484 ARDITKMIESELDYPGHIKVTVIRETRAVEYAK 516 ARDITK IE+ELDYPGHIKVTVIRETRAV+YAK Sbjct: 481 ARDITKTIENELDYPGHIKVTVIRETRAVDYAK 513 >B1DLE8.1 B1DLE8_9BACL RNA binding metal dependent phosphohydrolase Length = 429 Score = 748 bits (1931), Expect = 0.0, Method: Compositional matrix adjust. Identities = 375/415 (90%), Positives = 395/415 (95%) Query: 102 DKKMESLERKEEQVANKEKRIDETQQQIDVIYKNQVTELERISNLSIDDARSIILSNVEQ 161 DKK+E+LERKEE VANKEKRIDETQ+QI+ IYK Q++ELERIS+L+++DA+SIILSNVEQ Sbjct: 15 DKKIEALERKEELVANKEKRIDETQEQIESIYKQQLSELERISSLTMEDAKSIILSNVEQ 74 Query: 162 EVRHETAQMIKEIEQQAKEEADKKAREIITLAIQRCAADHVAETTVSVVTLPNEEMKXXX 221 EVRHETAQMIKEIEQQAKEEAD+KAR+II+LAIQRCAADHVAETTVSVVTLPNEEMK Sbjct: 75 EVRHETAQMIKEIEQQAKEEADRKARDIISLAIQRCAADHVAETTVSVVTLPNEEMKGRI 134 Query: 222 XXXXXXXXXALETLTGIDLIIDDTPEAVILSGFDPIRREVARTALEKLVADGRIHPARIE 281 ALETLTGIDLIIDDTPEAVILSGFDPIRRE+ART+LEKLVADGRIHPARIE Sbjct: 135 IGREGRNIRALETLTGIDLIIDDTPEAVILSGFDPIRREIARTSLEKLVADGRIHPARIE 194 Query: 282 EMVEKSRKEVDERIREYGEQATFEVGVHGLHPDLIKILGRLKFRTSYGQNVLKHSMEVAY 341 EMVEKSRKEVDERIREYGEQATFEVGVHGLHPDLIKILGRLK+RTSYGQNVLKHSMEVAY Sbjct: 195 EMVEKSRKEVDERIREYGEQATFEVGVHGLHPDLIKILGRLKYRTSYGQNVLKHSMEVAY 254 Query: 342 LTGLMAGELGEDIVLAKRAGLLHDIGKALDHEVEGSHVEIGVELAKKYKEHPVVINSIAS 401 LTGLMA ELGEDI LAKRAGLLHDIGKALDHEVEGSHVEIGVELAKKYKEHPVVINSIAS Sbjct: 255 LTGLMAAELGEDITLAKRAGLLHDIGKALDHEVEGSHVEIGVELAKKYKEHPVVINSIAS 314 Query: 402 HHGDCEATSVIAMLVGAADALSAARPGARRETLETYIKRLEKLEEISESFEGVEKSYAIQ 461 HHGD EATSVIAMLVGAADALSAARPGARRETLETYIKRLEKLE+ISESF+GVEKS+AIQ Sbjct: 315 HHGDVEATSVIAMLVGAADALSAARPGARRETLETYIKRLEKLEDISESFDGVEKSFAIQ 374 Query: 462 AGREVRVMVQPEKIDDAEAFRLARDITKMIESELDYPGHIKVTVIRETRAVEYAK 516 AGREVRVMVQPEKIDD EAFRLARDITK IESELDYPGHIKVTVIRETRAVEYAK Sbjct: 375 AGREVRVMVQPEKIDDTEAFRLARDITKKIESELDYPGHIKVTVIRETRAVEYAK 429 >C0ZF12.1 C0ZF12_BREBN 2',3'-cyclic-nucleotide 2'-phosphodiesterase EC=3.1.4.16 Length = 513 Score = 681 bits (1756), Expect = 0.0, Method: Compositional matrix adjust. Identities = 339/415 (81%), Positives = 376/415 (90%) Query: 102 DKKMESLERKEEQVANKEKRIDETQQQIDVIYKNQVTELERISNLSIDDARSIILSNVEQ 161 D+KME LERKEE+++ +++ I E Q +++ +YK QV+ELERIS L+ D+A++IIL++VE Sbjct: 99 DRKMEQLERKEEELSERDRAIAELQSKVEHLYKEQVSELERISGLTQDEAKTIILTDVEN 158 Query: 162 EVRHETAQMIKEIEQQAKEEADKKAREIITLAIQRCAADHVAETTVSVVTLPNEEMKXXX 221 VRHE A MIKEIE QAKEEADK+AREIIT +IQRCAADHVAETTVSVVTLPN+EMK Sbjct: 159 TVRHEMAVMIKEIETQAKEEADKRAREIITTSIQRCAADHVAETTVSVVTLPNDEMKGRI 218 Query: 222 XXXXXXXXXALETLTGIDLIIDDTPEAVILSGFDPIRREVARTALEKLVADGRIHPARIE 281 ALETLTGIDLIIDDTPEAVILSGFDPIRRE+A+TAL+KLVADGRIHPARIE Sbjct: 219 IGREGRNIRALETLTGIDLIIDDTPEAVILSGFDPIRREIAKTALDKLVADGRIHPARIE 278 Query: 282 EMVEKSRKEVDERIREYGEQATFEVGVHGLHPDLIKILGRLKFRTSYGQNVLKHSMEVAY 341 EMVEK+R+EVDERIREYGEQATFE GVHGLHPDLIKILGRL++RTSYGQNVLKHSMEVA+ Sbjct: 279 EMVEKARREVDERIREYGEQATFETGVHGLHPDLIKILGRLRYRTSYGQNVLKHSMEVAH 338 Query: 342 LTGLMAGELGEDIVLAKRAGLLHDIGKALDHEVEGSHVEIGVELAKKYKEHPVVINSIAS 401 L GLMA EL ED+ LAKRAGLLHDIGKA+DHEVEGSHVEIGVELAKKY EH VV+NSIAS Sbjct: 339 LAGLMAAELKEDVKLAKRAGLLHDIGKAIDHEVEGSHVEIGVELAKKYNEHHVVVNSIAS 398 Query: 402 HHGDCEATSVIAMLVGAADALSAARPGARRETLETYIKRLEKLEEISESFEGVEKSYAIQ 461 HHGD E TSVIAMLVGAADALSAARPGARRETLETYI+RLEKLEEISESF+GVEKSYAIQ Sbjct: 399 HHGDTEPTSVIAMLVGAADALSAARPGARRETLETYIRRLEKLEEISESFDGVEKSYAIQ 458 Query: 462 AGREVRVMVQPEKIDDAEAFRLARDITKMIESELDYPGHIKVTVIRETRAVEYAK 516 AGRE+RVMVQP+KIDDAEA RLARDITK IE+ELDYPGHIKVTVIRETRAVEYAK Sbjct: 459 AGREIRVMVQPDKIDDAEATRLARDITKRIENELDYPGHIKVTVIRETRAVEYAK 513 >Q9KAB2.1 CNPD_BACHD 2',3'-cyclic-nucleotide 2'-phosphodiesterase EC=3.1.4.16 Length = 521 Score = 623 bits (1607), Expect = e-176, Method: Compositional matrix adjust. Identities = 319/415 (76%), Positives = 362/415 (87%) Query: 102 DKKMESLERKEEQVANKEKRIDETQQQIDVIYKNQVTELERISNLSIDDARSIILSNVEQ 161 DKK ESL+++EE + K+++I+E +++ I Q ELERIS S ++AR +I + VEQ Sbjct: 107 DKKEESLDKREESLTKKQRQIEEMDSKVEEILNKQQVELERISGFSREEAREVIRAEVEQ 166 Query: 162 EVRHETAQMIKEIEQQAKEEADKKAREIITLAIQRCAADHVAETTVSVVTLPNEEMKXXX 221 E+ HETA +IKE +AKEEADKKAREI++LAIQRC+ADHVAETTVSVV LPN+EMK Sbjct: 167 EMAHETALLIKERVAKAKEEADKKAREILSLAIQRCSADHVAETTVSVVNLPNDEMKGRI 226 Query: 222 XXXXXXXXXALETLTGIDLIIDDTPEAVILSGFDPIRREVARTALEKLVADGRIHPARIE 281 ALETLTGIDLIIDDTPEAVILSGFDPIRRE+ARTALEKLV DGRIHPARIE Sbjct: 227 IGREGRNIRALETLTGIDLIIDDTPEAVILSGFDPIRREIARTALEKLVQDGRIHPARIE 286 Query: 282 EMVEKSRKEVDERIREYGEQATFEVGVHGLHPDLIKILGRLKFRTSYGQNVLKHSMEVAY 341 EMV+K+R+EVDE IREYGEQ TFE+G+HGLHPDLIKILGRLKFRTSYGQNVLKHSMEVAY Sbjct: 287 EMVDKARREVDEAIREYGEQTTFEMGIHGLHPDLIKILGRLKFRTSYGQNVLKHSMEVAY 346 Query: 342 LTGLMAGELGEDIVLAKRAGLLHDIGKALDHEVEGSHVEIGVELAKKYKEHPVVINSIAS 401 L GLMA ELGED+ LA+RAGLLHDIGKA+DHEVEGSHVEIGVELA KYKEHPVVIN+IAS Sbjct: 347 LAGLMAAELGEDVKLARRAGLLHDIGKAIDHEVEGSHVEIGVELATKYKEHPVVINAIAS 406 Query: 402 HHGDCEATSVIAMLVGAADALSAARPGARRETLETYIKRLEKLEEISESFEGVEKSYAIQ 461 HHGD EATS+I+ LV AADALSAARPGARRETLETYI+RLEKLEEISESF+GVEK+YAIQ Sbjct: 407 HHGDTEATSIISSLVAAADALSAARPGARRETLETYIRRLEKLEEISESFDGVEKTYAIQ 466 Query: 462 AGREVRVMVQPEKIDDAEAFRLARDITKMIESELDYPGHIKVTVIRETRAVEYAK 516 AGREVR+MV+P+ +DD A +LARDITK IE ELDYPGHI+VTVIRETRAVEYAK Sbjct: 467 AGREVRIMVKPDIVDDVLAHKLARDITKKIEEELDYPGHIRVTVIRETRAVEYAK 521 >Q5WFX6.1 CNPD_BACSK 2',3'-cyclic-nucleotide 2'-phosphodiesterase EC=3.1.4.16 Length = 525 Score = 619 bits (1595), Expect = e-175, Method: Compositional matrix adjust. Identities = 315/415 (75%), Positives = 363/415 (87%) Query: 102 DKKMESLERKEEQVANKEKRIDETQQQIDVIYKNQVTELERISNLSIDDARSIILSNVEQ 161 DKK ESLE++EE +A K+++++E + ++ + Q ELER+S LS ++AR II VEQ Sbjct: 111 DKKEESLEKREESLAKKQRQVEEMESKMSQLLVEQKQELERVSGLSREEARMIIRQEVEQ 170 Query: 162 EVRHETAQMIKEIEQQAKEEADKKAREIITLAIQRCAADHVAETTVSVVTLPNEEMKXXX 221 E+ HETA +IKE +AKE ADK+++EI++LAIQRC+ADHVAETTVSVV LPN+EMK Sbjct: 171 EIAHETALLIKEKTAEAKETADKRSKEILSLAIQRCSADHVAETTVSVVNLPNDEMKGRI 230 Query: 222 XXXXXXXXXALETLTGIDLIIDDTPEAVILSGFDPIRREVARTALEKLVADGRIHPARIE 281 ALETLTGIDLIIDDTPEAVILSGFDPIRRE+AR+ALEKLV DGRIHPARIE Sbjct: 231 IGREGRNIRALETLTGIDLIIDDTPEAVILSGFDPIRREIARSALEKLVQDGRIHPARIE 290 Query: 282 EMVEKSRKEVDERIREYGEQATFEVGVHGLHPDLIKILGRLKFRTSYGQNVLKHSMEVAY 341 EMV+KSR+EVDE IREYGEQ TFEVGVHGLHPDLIKILGRL+FRTSYGQNVLKHSMEVA+ Sbjct: 291 EMVDKSRREVDETIREYGEQTTFEVGVHGLHPDLIKILGRLRFRTSYGQNVLKHSMEVAH 350 Query: 342 LTGLMAGELGEDIVLAKRAGLLHDIGKALDHEVEGSHVEIGVELAKKYKEHPVVINSIAS 401 L G+MA ELGED+ LAKRAGLLHDIGKA+DHEVEGSHVEIGVELA KYKEHPVVIN+IAS Sbjct: 351 LAGIMAAELGEDVKLAKRAGLLHDIGKAIDHEVEGSHVEIGVELATKYKEHPVVINAIAS 410 Query: 402 HHGDCEATSVIAMLVGAADALSAARPGARRETLETYIKRLEKLEEISESFEGVEKSYAIQ 461 HHGD E+TS+I+ LV AADALSAARPGARRETLETYI+RLEKLEEISESF+GVEK++AIQ Sbjct: 411 HHGDTESTSIISTLVAAADALSAARPGARRETLETYIRRLEKLEEISESFDGVEKTFAIQ 470 Query: 462 AGREVRVMVQPEKIDDAEAFRLARDITKMIESELDYPGHIKVTVIRETRAVEYAK 516 AGREVR+MV+P+ +DDA A +LARDITK IE ELDYPGHI+VTVIRETRAVEYAK Sbjct: 471 AGREVRIMVRPDVVDDALAHKLARDITKKIEQELDYPGHIRVTVIRETRAVEYAK 525 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.316 0.133 0.359 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,205,116,530 Number of extensions: 82088621 Number of successful extensions: 426034 Number of sequences better than 1.0e-05: 688 Number of HSP's gapped: 425679 Number of HSP's successfully gapped: 688 Length of query: 516 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 376 Effective length of database: 1,741,754,103 Effective search space: 654899542728 Effective search space used: 654899542728 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 134 (56.2 bits)