BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0273.0011.p (484 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KC26.1 B3KC26_9BACI Sensor protein EC=2.7.13.3 373 e-101 A3I5H2.1 A3I5H2_9BACI Sensor protein EC=2.7.13.3 368 e-100 Q97M81.1 Q97M81_CLOAB Sensor protein EC=2.7.13.3 161 2e-37 Q65HY2.1 Q65HY2_BACLD Sensor protein EC=2.7.13.3 157 2e-36 B0MI01.1 B0MI01_9FIRM Sensor protein EC=2.7.13.3 155 1e-35 >B3KC26.1 B3KC26_9BACI Sensor protein EC=2.7.13.3 Length = 479 Score = 373 bits (957), Expect = e-101, Method: Compositional matrix adjust. Identities = 190/413 (46%), Positives = 266/413 (64%), Gaps = 7/413 (1%) Query: 75 IREELLMWSQQKKLNLLYAGLDGTVLFDSSTPLLSGQDKLALKNELHYDLSSARTELGSF 134 IRE+L WSQ+ ++ L DGT+++DS S ++ + EL Y L + + + Sbjct: 69 IREKLTSWSQETRIGLKVVLPDGTMIYDSDD---SSVRRIHPRFELDYTLRMSDGDPPEY 125 Query: 135 RLAFPVIDSKSGIQAGNAVFTLPESALAYGQAAS--FPVTAAXXXXXXXXXXXXXXXXXX 192 LAFP++D+ + AG A FT+P SA+ +S V Sbjct: 126 HLAFPLLDAGTNAFAGYAQFTVPASAVTAAIPSSGLLLVVPWISLSLALLTLLYVIFSAG 185 Query: 193 XXXXXXXXXXIAGLKDHSEAILKGDYEKKAEYGTQNEIGEVYAVFDQMRSEMMELSLQRE 252 +AGLK ++EAILKGDYE++AE+ + NE+GE+YAVFD MR E+ L +Q+ Sbjct: 186 RRVQRDLVEPVAGLKPYAEAILKGDYEQRAEWTSNNEVGELYAVFDLMREEIRNLHMQQA 245 Query: 253 AQDKAQKELISNISHDLKTPLTAVKAYIEAIQAGVCPDLPAVMEYMDIIQTQTNKMAGLV 312 + ++ KELISN+SHDLKTPL +KAYI+AI+ G+CPDLP+VM Y++++ T+KMA LV Sbjct: 246 SHSQSHKELISNLSHDLKTPLATIKAYIDAIREGICPDLPSVMTYLEVVHANTSKMAVLV 305 Query: 313 EDLLVHALRDLGQISVNPVECYSREIFESILKPMGPYIRRTGVEFTGPTEIPNVLIRIDP 372 +DLL+HALRDL QI+V P+E YS E +L+ M YIR GV P+ IPNVL+ ID Sbjct: 306 DDLLLHALRDLDQIAVRPLEQYSSSTIEPVLRTMAHYIRTMGVRCVEPSSIPNVLVIIDA 365 Query: 373 VRMEQLLSNLIANALKHTAAGDSIRIAIDR--QQDQLKLTVADTGEGILQQDMPFIFERY 430 VR EQ+++NL+ NALKHT GD+I +A++ + L++ ++DTG GI QDMPFIFERY Sbjct: 366 VRFEQVIANLVTNALKHTKPGDTITLAVEEFAESSSLRIIISDTGSGISPQDMPFIFERY 425 Query: 431 FQGHAPSQYEKRFKEGSGLGLSICKHIIEAHHGSISFKSIKHQGTEFYLTLPL 483 +QG P + + + G GLGLSICK+I+EAH G+I+F S + QGT F LTLPL Sbjct: 426 YQGSVPDRKKLAERHGVGLGLSICKYIMEAHGGTITFHSKQQQGTTFCLTLPL 478 >A3I5H2.1 A3I5H2_9BACI Sensor protein EC=2.7.13.3 Length = 480 Score = 368 bits (944), Expect = e-100, Method: Compositional matrix adjust. Identities = 190/484 (39%), Positives = 285/484 (58%), Gaps = 6/484 (1%) Query: 1 MYWSSWFKAWFASAIACIILFAVCGTFLTYKLLHQKQSAFPPYVVNQARVEVSDIMFXXX 60 MY W W + I C+ L + L + ++ + YV+NQ R+ V+ ++ Sbjct: 1 MYLKKWINKWIWTLIICVGLLFIGTLILFFATNKSQEVSEDQYVINQIRLSVNQLLLYIE 60 Query: 61 XXXXXXXRAGGQPNIREELLMWSQQKKLNLLYAGLDGTVLFDSSTPLLSGQDKLALKNEL 120 R IR L S +++++ LDG V+F + L+ + +KN++ Sbjct: 61 DHLSILERDS---EIRSMLQQMSDDQEIDMTVLHLDGKVIFHTKENDLTS--TIQIKNDI 115 Query: 121 HYDLSSARTELGSFRLAFPVIDSKSGIQAGNAVFTLPESAL-AYGQAASFPVTAAXXXXX 179 HYDL +++ E G +AFP+++ +S Q GNA+FTL + +L Q S + Sbjct: 116 HYDLFTSQQEPGKINIAFPIVNDESHEQIGNAIFTLNKDSLFPSKQPNSNYLFLVVMMGA 175 Query: 180 XXXXXXXXXXXXXXXXXXXXXXXIAGLKDHSEAILKGDYEKKAEYGTQNEIGEVYAVFDQ 239 + LK ++E I+KG+YE+ + Y +E+GE+YAVFDQ Sbjct: 176 LSFFIICFALYMNRKVQKDILTPLHELKKNTEEIVKGNYEQMSSYPKLDELGELYAVFDQ 235 Query: 240 MRSEMMELSLQREAQDKAQKELISNISHDLKTPLTAVKAYIEAIQAGVCPDLPAVMEYMD 299 MR E+ +L +QR Q++ QK+LISNISHD+KTPLT +KAY++AI GVC D ++M Y+ Sbjct: 236 MRLEIKQLVIQRNEQEQHQKKLISNISHDVKTPLTTIKAYLDAISEGVCRDEDSLMSYIH 295 Query: 300 IIQTQTNKMAGLVEDLLVHALRDLGQISVNPVECYSREIFESILKPMGPYIRRTGVEFTG 359 I+Q T KM+ L+EDL +H L++LG I ++ E YSR++ +IL+P+ Y++ T + F Sbjct: 296 IMQINTEKMSRLIEDLFIHTLKELGHIPIHLKEQYSRDVLTNILQPIHYYVQTTNIHFIK 355 Query: 360 PTEIPNVLIRIDPVRMEQLLSNLIANALKHTAAGDSIRIAIDRQQDQLKLTVADTGEGIL 419 P IPNVLI++D R+EQ++SNL+ NALKHT+ GD+I I + L + V D G G+L Sbjct: 356 PAMIPNVLIQVDEGRLEQVISNLVTNALKHTSNGDTITITTYIEDQTLYIQVIDNGNGML 415 Query: 420 QQDMPFIFERYFQGHAPSQYEKRFKEGSGLGLSICKHIIEAHHGSISFKSIKHQGTEFYL 479 +DMPFIFERYF+GH + EG+GLGLSIC+HI+E H+GSISF S +GT F L Sbjct: 416 PEDMPFIFERYFRGHQAERESAIKNEGAGLGLSICQHIMEEHYGSISFHSKHKEGTTFTL 475 Query: 480 TLPL 483 TLP+ Sbjct: 476 TLPI 479 >Q97M81.1 Q97M81_CLOAB Sensor protein EC=2.7.13.3 Length = 498 Score = 161 bits (407), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 98/282 (34%), Positives = 163/282 (57%), Gaps = 9/282 (3%) Query: 206 LKDHSEAILKGDYEKKAEYGTQNEIGEVYAVFDQMRSEMMELSLQREAQ-DKAQKELISN 264 LK +E I G+ + K + +EIGE+ FD MR ++ E S++ +AQ + +KELISN Sbjct: 217 LKIGTEKIKHGNLDFKVRAESSDEIGELCDAFDSMRKKLKE-SVELQAQYENNRKELISN 275 Query: 265 ISHDLKTPLTAVKAYIEAIQAGVCPDLPAVME-YMDIIQTQTNKMAGLVEDLLVHALRDL 323 ISHDLKTP+T++K YIE I+ GV D P ME Y++ I +T M L+E+LL ++ DL Sbjct: 276 ISHDLKTPITSIKGYIEGIRDGVA-DTPEKMEKYVNTIYNKTQSMNYLIEELLTYSKLDL 334 Query: 324 GQISVNPVECYSREIFESILKPMGPYIRRTGVEFTGPTEIP-NVLIRIDPVRMEQLLSNL 382 ++ ++ +++ + + +EF+ I +RID + +++SN+ Sbjct: 335 KKLPFYFIDMDFVSYMNDLMEEFKFDVEKNNMEFSYDNHIKGKANVRIDVQNINRVISNI 394 Query: 383 IANALKH-TAAGDSIRIAIDRQQDQLKLTVADTGEGILQQDMPFIFERYFQGHAPSQYEK 441 I+N++K+ I + +D +++ + + D G GI ++ +P++F+R+++ K Sbjct: 395 ISNSIKYMDKEHGKISVEVDSNNEEVLVGIKDNGMGISEEALPYVFDRFYREDFSRNTSK 454 Query: 442 RFKEGSGLGLSICKHIIEAHHGSISFKSIKHQGTEFYLTLPL 483 GSGLGL+ICK IIE H GSI KS K GTE + ++ L Sbjct: 455 G---GSGLGLAICKKIIEEHGGSIWAKSQKGHGTEIWFSIKL 493 >Q65HY2.1 Q65HY2_BACLD Sensor protein EC=2.7.13.3 Length = 593 Score = 157 bits (397), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 83/230 (36%), Positives = 136/230 (59%), Gaps = 7/230 (3%) Query: 255 DKAQKELISNISHDLKTPLTAVKAYIEAIQAGVCPDLPAVMEYMDIIQTQTNKMAGLVED 314 DK +K+ I+N+SH+L+TP++ ++ Y EAI + E +I ++ +M LV D Sbjct: 360 DKLRKDFIANVSHELRTPISMLQGYSEAIVDDIASSEEEKKEIAQVIYDESLRMGRLVND 419 Query: 315 LLVHALRDLGQISVN--PVECYSREIFESILKPMGPYIRRTGVEFTGPTEIPNVLIRIDP 372 LL A + G IS+N PVE RE FE + + + + ++ DP Sbjct: 420 LLDLARMEAGHISLNVEPVEL--REFFERVFRKFYGVAGDKNITLSHNLDLHEAKFVFDP 477 Query: 373 VRMEQLLSNLIANALKHTAAGDSIRIAIDRQQDQLKLTVADTGEGILQQDMPFIFERYFQ 432 +MEQ+L+NLI NA++HT AG ++ + + + LK+ V D+G GI ++D+PFIFER+++ Sbjct: 478 DKMEQVLTNLIDNAIRHTNAGGTVHVDVQSAESGLKIAVKDSGSGIPEEDLPFIFERFYK 537 Query: 433 GHAPSQYEKRFKEGSGLGLSICKHIIEAHHGSISFKSIKHQGTEFYLTLP 482 + R K G+GLGL+I K+I++AH+GSI+ S+ ++GT F +P Sbjct: 538 A---DKARTRGKGGTGLGLAIVKNIVDAHNGSITVHSMLNEGTSFTFYIP 584 >B0MI01.1 B0MI01_9FIRM Sensor protein EC=2.7.13.3 Length = 497 Score = 155 bits (391), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 95/279 (34%), Positives = 156/279 (55%), Gaps = 8/279 (2%) Query: 206 LKDHSEAILKGDYEKKAEYGTQNEIGEVYAVFDQMRSEMMELSLQREAQDKAQKELISNI 265 LK+ ++ I +G+ + E +++EIGE+ A F+ MR+E+ E R +K ++LISNI Sbjct: 211 LKEGADRIKEGNLDDDVEINSKDEIGELCASFNAMRAELKESIEARIIYEKQNRDLISNI 270 Query: 266 SHDLKTPLTAVKAYIEAIQAGVCPDLPAVME-YMDIIQTQTNKMAGLVEDLLVHALRDLG 324 SHDLKTP+TA+K Y+E I GV D P M+ Y+ I + N M L+ +L +++ D Sbjct: 271 SHDLKTPITAIKGYVEGIMDGVA-DTPEKMDRYIKTIYNKANDMDVLINELSLYSKIDSN 329 Query: 325 QISVNPVECYSREIFESILKPMGPYIRRTGVEFTGPTEIP-NVLIRIDPVRMEQLLSNLI 383 I N + F+ + +G + + G+ F+ NV + DP +++++++N+I Sbjct: 330 IIPYNFRKIDINAYFKDCVDEIGSDLEQKGMMFSYSNYCSANVAVMADPEQLKRVMNNII 389 Query: 384 ANALKHT-AAGDSIRIAIDRQQDQLKLTVADTGEGILQQDMPFIFERYFQGHAPSQYEKR 442 NA K+T A + I + ++++ + D G GI ++D+P IF R ++ + + Sbjct: 390 NNACKYTNKAKGKVSITLKELDRKIQVAIKDNGIGISKEDLPNIFRRTYR----ADMSRN 445 Query: 443 FKEGSGLGLSICKHIIEAHHGSISFKSIKHQGTEFYLTL 481 GSGLGLSICK IIE H G I +S GT + TL Sbjct: 446 SAGGSGLGLSICKKIIEEHGGEIWAESRLRSGTTIFFTL 484 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.135 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,530,816,555 Number of extensions: 94923512 Number of successful extensions: 367388 Number of sequences better than 1.0e-05: 27921 Number of HSP's gapped: 320694 Number of HSP's successfully gapped: 28026 Length of query: 484 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 344 Effective length of database: 1,741,754,103 Effective search space: 599163411432 Effective search space used: 599163411432 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 133 (55.8 bits)