BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0271.0011.p (585 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KBQ3.1 B3KBQ3_9BACI Sensor protein EC=2.7.13.3 746 0.0 B1D726.1 B1D726_9BACL Sensor protein EC=2.7.13.3 566 e-159 A0P8X1.1 A0P8X1_BACCI Putative two-component sensor histidine ki... 435 e-120 C0Z7X8.1 C0Z7X8_BREBN Two-component sensor histidine kinase EC=2... 422 e-116 C1P968.1 C1P968_BACCO PAS/PAC sensor signal transduction histidi... 404 e-110 >B3KBQ3.1 B3KBQ3_9BACI Sensor protein EC=2.7.13.3 Length = 605 Score = 746 bits (1925), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/588 (62%), Positives = 461/588 (78%), Gaps = 7/588 (1%) Query: 1 MALIGISMIGAGITMAKLFKDSHISALEENMSREINLLSGTFQFTDTDSPGAVSYYTEQA 60 + LIG+SM+ AG+ M +FK SHI LE+NM REI LL +F DTD AVSYYT+++ Sbjct: 13 LTLIGLSMLAAGLAMVTVFKQSHIQLLEDNMVREIRLLQTMMEFPDTDGAEAVSYYTDRS 72 Query: 61 EHIAKLTNSRITFITKDGKVIGDSEKNPLEMDNHSTREEEVLAAKEGIGRAIRYSDTLNR 120 + +L+++R+TFI KDG+VIGDSE +PL MDNH+ REE + A KEG G IR SDTL + Sbjct: 73 LQLEELSDARVTFILKDGRVIGDSESDPLTMDNHAYREEMLQALKEGRGSTIRRSDTLQQ 132 Query: 121 EMLYVAGAVVSDQGFDGYIRLSMALDAVTEGLNRAWMVMAGGLVLLFIAATFVSYKVASG 180 +MLYVA V + + FDG++RLS++L V +G+ + W VM GL++LF+ A VSY+VA G Sbjct: 133 DMLYVALPVKAGENFDGFVRLSVSLKEVDQGVKQGWTVMGIGLLVLFLIAALVSYRVAQG 192 Query: 181 MTSPLEQITRVARRITDLDYDARVPMNRRDEIGQLATAINAMADSLQAQLKTIRDNEDLL 240 +TSPLE+ITRVARRI+ L+YDARV ++R+DEIGQLA AIN MADSLQ QL+TIRDNEDLL Sbjct: 193 LTSPLEKITRVARRISRLEYDARVKIHRKDEIGQLAQAINGMADSLQTQLRTIRDNEDLL 252 Query: 241 QSVLDNMTGGIVMINAEGEIALLNRAAEQLLDVKNSEMAGHSFKELKHHYELSRLIEEGV 300 QSVL+NMTGGIV+++ G+I L+NRAAE++L + + G S++ELK HYEL++L+EEG+ Sbjct: 253 QSVLNNMTGGIVLVSGAGQIILVNRAAEKMLGINAEVITGKSYRELKQHYELTKLMEEGL 312 Query: 301 SRNEAVHEERSIYNPTERIVRLDGVPMIQDGSN----RGMLFLLQEVTEIRRLEKMRSEF 356 HEER++Y P E I+R+DGV M+Q+ RGMLFLLQ+V++IRRLE+MRSEF Sbjct: 313 GSQADFHEERNVYYPVESIIRIDGVTMMQEEEQEPYRRGMLFLLQDVSDIRRLERMRSEF 372 Query: 357 VANVSHELKTPVAAVKGFAETLLGGGVKDEKTARSFLQIIYDENERLNRLIGDILELSKI 416 VANVSHELKTP+AAVKGFAETLLGGGV DEKT+RSFLQIIYDE+ERLNRLIGDILELSKI Sbjct: 373 VANVSHELKTPLAAVKGFAETLLGGGVTDEKTSRSFLQIIYDESERLNRLIGDILELSKI 432 Query: 417 ESKRAQLECSPVHLIEFFDSLLETLSKVAEKKNISLNASVPEELFMEGDEDKLRQIFINL 476 ESKR Q++ SP+HL FFD++ E + VAEKK I L VPEELFMEGDEDKLRQIF+NL Sbjct: 433 ESKRIQMDYSPIHLSAFFDTISEMMRTVAEKKRIGLELDVPEELFMEGDEDKLRQIFMNL 492 Query: 477 ISNAINYTQDGGSXXXXXXXGQKADGT--ETVVFTVRDTGMGIPRKDLPRIFERFYRVDK 534 +SNAI+YTQ+GG + DG+ + V F V+D+G+GIP+KDLPRIFERFYRVDK Sbjct: 493 LSNAISYTQEGGRVKLTARE-KHNDGSADDFVEFVVKDSGIGIPKKDLPRIFERFYRVDK 551 Query: 535 AXXXXXXXXXXXXXIVKHLVELHHGSISVESDLGIGSSFILELPLLQD 582 A IVKHLV+LHHG+I VES+LGIGSSFI+ELP+LQ+ Sbjct: 552 ARSRGSGGTGLGLSIVKHLVDLHHGTIKVESELGIGSSFIIELPILQE 599 >B1D726.1 B1D726_9BACL Sensor protein EC=2.7.13.3 Length = 591 Score = 566 bits (1458), Expect = e-159, Method: Compositional matrix adjust. Identities = 294/580 (50%), Positives = 402/580 (69%), Gaps = 5/580 (0%) Query: 3 LIGISMIGAGITMAKLFKDSHISALEENMSREINLLSGTFQFTDTDSPGAVSYYTEQAEH 62 ++ +S+ AG+ MAK FKD+HI+ALE+NM RE++++ ++ D+ Y+T++AE Sbjct: 15 ILALSVTAAGLFMAKTFKDNHINALEDNMVREMHIILAKTEWKQGDNAVLFPYFTKEAET 74 Query: 63 IAKLTNSRITFITKDGKVIGDSEKNPLEMDNHSTREEEVLAAKEGIGRAIRYSDTLNREM 122 + +SR+TFI DG V+GDS+ P MDNHS R E V A K+GIGRAIRYSDTL + Sbjct: 75 LRTYADSRVTFIAGDGTVLGDSDHAPETMDNHSKRVEVVEAHKDGIGRAIRYSDTLKENL 134 Query: 123 LYVAGAVVSDQGFDGYIRLSMALDAVTEGLNRAWMVMAGGLVLLFIAATFVSYKVASGMT 182 LYVA IRL+M+L V + +++ W V+ GL++LFI A F+SY++A +T Sbjct: 135 LYVAITANPSDPNSNVIRLAMSLKEVDKSIDQLWTVLIIGLLILFIVAAFISYRIALSLT 194 Query: 183 SPLEQITRVARRITDLDYDARVPMNRRDEIGQLATAINAMADSLQAQLKTIRDNEDLLQS 242 PLEQIT+VA+RI +DY ARV + ++DE+G+L AINAMA+SL+ Q+ IR NE L+S Sbjct: 195 RPLEQITKVAQRIKQMDYKARVKVRKQDEVGELGHAINAMAESLEVQMTRIRQNESQLES 254 Query: 243 VLDNMTGGIVMINAEGEIALLNRAAEQLLDVKNSEMAGHSFKELKHHYELSRLIEEGVSR 302 VLDNM G++MI+ G+I L++R A +LL + + E+ G ++ E K YELS+LI+E + Sbjct: 255 VLDNMINGVMMIDPAGKILLMSRRAGELLGISSGELVGRNYAEAKQQYELSQLIQEALEG 314 Query: 303 NEAVHEERSIYNPTERIVRLDGVPMIQDGSN-RGMLFLLQEVTEIRRLEKMRSEFVANVS 361 E + EE + Y P ER++ L+ VP+ Q+ G+L +L +VT IRRLE+MRSEFVANVS Sbjct: 315 REHIREEITFYFPEERLLELNLVPINQENQEFGGVLLVLADVTAIRRLERMRSEFVANVS 374 Query: 362 HELKTPVAAVKGFAETLLGGGVKDEKTARSFLQIIYDENERLNRLIGDILELSKIESKRA 421 HELKTP+AAVKGFAETLLGG V DE+TARSFLQIIYDE++RLNRLIGDIL LSKIESKR Sbjct: 375 HELKTPIAAVKGFAETLLGGAVNDEETARSFLQIIYDESDRLNRLIGDILALSKIESKRV 434 Query: 422 QLECSPVHLIEFFDSLLETLSKVAEKKNISLNASVPEELFMEGDEDKLRQIFINLISNAI 481 L SPV + F + + A KK+I L + L++E DED+LRQI +N+I+N + Sbjct: 435 PLYFSPVEMDSFMTKTVTMMESEAAKKSIKLQLEMEHGLYVEADEDRLRQIMMNVIANGV 494 Query: 482 NYTQDGGSXXXXXXXGQKADGTETVVFTVRDTGMGIPRKDLPRIFERFYRVDKAXXXXXX 541 NYT +GG ++ + + + DTG+GIP+KDLPRIFERFYRVDKA Sbjct: 495 NYTPEGGKVSVNI----ESIDEDHIRIQISDTGIGIPKKDLPRIFERFYRVDKARSRSSG 550 Query: 542 XXXXXXXIVKHLVELHHGSISVESDLGIGSSFILELPLLQ 581 IVKHLVELH G+I+V S +G+GS+F++ELP+LQ Sbjct: 551 GTGLGLSIVKHLVELHKGTIAVTSAVGVGSTFVIELPVLQ 590 >A0P8X1.1 A0P8X1_BACCI Putative two-component sensor histidine kinase (Fragment) Length = 253 Score = 435 bits (1118), Expect = e-120, Method: Compositional matrix adjust. Identities = 209/241 (86%), Positives = 224/241 (92%) Query: 1 MALIGISMIGAGITMAKLFKDSHISALEENMSREINLLSGTFQFTDTDSPGAVSYYTEQA 60 MALIGISM GAGITMA+LFKDSHIS LEENMSREI LLSGTF F DT SP A++YYTEQA Sbjct: 13 MALIGISMTGAGITMAQLFKDSHISVLEENMSREIKLLSGTFSFMDTSSPDALNYYTEQA 72 Query: 61 EHIAKLTNSRITFITKDGKVIGDSEKNPLEMDNHSTREEEVLAAKEGIGRAIRYSDTLNR 120 + I+ LT SR+TFITK G+VIGDSEKNP EMDNHSTREEE+LAAKEGIGRAIRYSDTL+R Sbjct: 73 QKISTLTGSRVTFITKQGRVIGDSEKNPREMDNHSTREEELLAAKEGIGRAIRYSDTLDR 132 Query: 121 EMLYVAGAVVSDQGFDGYIRLSMALDAVTEGLNRAWMVMAGGLVLLFIAATFVSYKVASG 180 EM+YVAG+V SDQGFDGYIRLSM LD V+EGLNRAWM+MAGGLVLLFIAATFVSYKVAS Sbjct: 133 EMMYVAGSVSSDQGFDGYIRLSMGLDTVSEGLNRAWMIMAGGLVLLFIAATFVSYKVASS 192 Query: 181 MTSPLEQITRVARRITDLDYDARVPMNRRDEIGQLATAINAMADSLQAQLKTIRDNEDLL 240 MTSPLEQITRVARRITDLDYDARVP+ R+DEIGQLATAINAMADSLQAQLKTIRDNEDLL Sbjct: 193 MTSPLEQITRVARRITDLDYDARVPLKRKDEIGQLATAINAMADSLQAQLKTIRDNEDLL 252 Query: 241 Q 241 Q Sbjct: 253 Q 253 >C0Z7X8.1 C0Z7X8_BREBN Two-component sensor histidine kinase EC=2.7.3.- Length = 587 Score = 422 bits (1086), Expect = e-116, Method: Compositional matrix adjust. Identities = 240/581 (41%), Positives = 360/581 (61%), Gaps = 9/581 (1%) Query: 1 MALIGISMIGAGITMAKLFKDSHISALEENMSREINLLSGTFQFTDTDSPGAVSYYTEQA 60 + LI + ++ G+ AK+ ++S++ +L E +SRE L++ +F D S A ++ Sbjct: 13 LGLISLVLLVMGMYFAKVLENSYLQSLNELLSRESKLIAQAVRFPDVFSDKAT--LEDRV 70 Query: 61 EHIAKLTNSRITFITKDGKVIGDSEKNPLEMDNHSTREEEVLAAKEGIGRAIRYSDTLNR 120 + +A RIT I KDG+V+ D+ + EM+NH R E A + G + R+S+TL Sbjct: 71 KQVAPADEVRITIIDKDGQVMYDNSSHSEEMENHHDRPEMKAALQGETGISRRFSETLGY 130 Query: 121 EMLYVAGAVVSDQGFDGYIRLSMALDAVTEGLNRAWMVMAGGLVLLFIAATFVSYKVASG 180 +M+YVA V + G +R +M++ +T+ +++ W + GL++ + + V +++ Sbjct: 131 DMMYVAVPVELNNEIFGVVRSAMSMKDITDTIHKMWYSLLTGLLVTLVVGSIVVSRISFS 190 Query: 181 MTSPLEQITRVARRITDLDYDARVPMNRRDEIGQLATAINAMADSLQAQLKTIRDNEDLL 240 + P+E+ITRVAR IT Y++RV + +DEIGQLA AIN MA SL+ Q+ I +N+ L Sbjct: 191 IIRPIEEITRVARNITQRQYESRVRIKAKDEIGQLAGAINFMASSLEQQMYEISENQQRL 250 Query: 241 QSVLDNMTGGIVMINAEGEIALLNRAAEQLLDVKNSEMAGHSFKELKHHYELSRLIEEGV 300 VL NMT G++ I+ + I L+N A E+LL E+ G E + LS+ I+ + Sbjct: 251 AGVLTNMTSGVIFISEQRRIMLVNPAVEKLLGTAGHEIVGKLHIEAGKSFGLSQYIDRCL 310 Query: 301 SRNEAVHEERSIYNPTERIVRLDGVPMIQ-DGSNRGMLFLLQEVTEIRRLEKMRSEFVAN 359 R+E +E IY P ERI+ ++ P I G +RG++ +L ++T+IRRLEKMRSEFVAN Sbjct: 311 DRSEKFRQEVHIYYPQERILDVNFAPYINFKGESRGVVVVLHDITDIRRLEKMRSEFVAN 370 Query: 360 VSHELKTPVAAVKGFAETLLGGGVKDEKTARSFLQIIYDENERLNRLIGDILELSKIESK 419 VSHEL+TP+ ++KGF ETLL G ++DE+T R+FLQII DE+ERL R+I DIL+LSKIE K Sbjct: 371 VSHELRTPITSIKGFTETLLEGAMQDEETCRNFLQIISDESERLYRMIRDILDLSKIEQK 430 Query: 420 RAQLECSPVHLIEFFDSLLETLSKVAEKKNISLNASVPE-ELFMEGDEDKLRQIFINLIS 478 R L VHL + S + + A++K +++ P+ ++++ D+D L+QI +NL++ Sbjct: 431 RIPLHLGQVHLQDLISSAVAIMHDQAQRKELTITLPSPKPDIWLMTDKDCLQQIILNLLT 490 Query: 479 NAINYTQDGGSXXXXXXXGQKADGTETVVFTVRDTGMGIPRKDLPRIFERFYRVDKAXXX 538 NAI YTQ+GG +AD +E + V DTG+GIP K+L RIFERFYRVDKA Sbjct: 491 NAIAYTQEGGKISIKT----EAD-SENITIQVMDTGIGIPEKELTRIFERFYRVDKARSR 545 Query: 539 XXXXXXXXXXIVKHLVELHHGSISVESDLGIGSSFILELPL 579 IVKHLVE HG ISVES G G++F + LPL Sbjct: 546 DSGGTGLGLAIVKHLVENLHGHISVESKEGRGTTFTVTLPL 586 >C1P968.1 C1P968_BACCO PAS/PAC sensor signal transduction histidine kinase Length = 595 Score = 404 bits (1037), Expect = e-110, Method: Compositional matrix adjust. Identities = 236/595 (39%), Positives = 346/595 (58%), Gaps = 26/595 (4%) Query: 1 MALIGISMIGAGITMAKLFKDSHISALEENMSREINLLSGTFQF-TDTDSP----GAVSY 55 ++++ ++ G +A + + +++ +S++ +LL T + T D P G V + Sbjct: 13 LSILAAVLLAIGFFVADMIQHTYMDMARTQLSQDADLLMKTIRPQTFKDKPDVLQGKVRH 72 Query: 56 YTEQAEHIAKLTNSRITFITKDGKVIGDSEKNPLEMDNHSTREE--EVLAAKEGIGRAIR 113 Y E RIT I +GKV+ DS+ +P +M+NH+ R E +V+ + G +IR Sbjct: 73 YYSNHE-------PRITIIDTNGKVLADSDDDPAKMENHANRPEFRQVIRQHKASGESIR 125 Query: 114 YSDTLNREMLYVAGAVVSDQGFDGYIRLSMAL---DAVTEGLNRAWMVMAGGLVLLFIAA 170 S TL M+YVA V + IR S+AL DAV +GL W + + + F+ + Sbjct: 126 SSHTLGYNMMYVANPVKENGKVIAVIRTSIALNRIDAVLKGL---WFSLGLAMAVAFLIS 182 Query: 171 TFVSYKVASGMTSPLEQITRVARRITDLDYDARVPMNRRDEIGQLATAINAMADSLQAQL 230 ++SY +A T P+E V+ R+ + DYD+RV +N E+ QL AIN +A +L+ Q+ Sbjct: 183 GWISYVLARKFTRPIEASIEVSNRLIEKDYDSRVRVNASGELRQLTKAINNLAHNLKQQM 242 Query: 231 KTIRDNEDLLQSVLDNMTGGIVMINAEGEIALLNRAAEQLLDVKNSEMAGHSFKELKHHY 290 I +NE L +VL+NM G+++I G I L+NRA E++ + + E+ G E + Sbjct: 243 NEIDENEQQLTAVLENMDSGVMLIQTSGRIMLVNRAMEEMTGLSSGELIGKRHIEAGKSF 302 Query: 291 ELSRLIEEGVSRNEAVHEERSIYNPTERIVRLDGVPMI-QDGSNRGMLFLLQEVTEIRRL 349 LS+LI+ + E +E +Y P ERI+ P + + G RG++ +L +VTE RRL Sbjct: 303 GLSQLIDRSLKTGERFRDEVHLYYPKERILDAHIAPYVGESGELRGVVAVLHDVTETRRL 362 Query: 350 EKMRSEFVANVSHELKTPVAAVKGFAETLLGGGVKDEKTARSFLQIIYDENERLNRLIGD 409 E++RSEFVANVSHELKTPV +VKGFAETLL G + DE T R FL+IIYDE++RL+RLI D Sbjct: 363 EQIRSEFVANVSHELKTPVTSVKGFAETLLDGAMYDEATLREFLKIIYDESDRLHRLISD 422 Query: 410 ILELSKIESKRAQLECSPVHLIEFFDSLLETLSKVAEKKNISLNASVPEELFMEGDEDKL 469 IL+LS+IE R L+ +++++ ++T+ K EKK + L + ME D+D+L Sbjct: 423 ILDLSRIEQHRILLKMEQLNVVDVVAETVQTMRKRIEKKQLELVLPQKRHVMMEADKDRL 482 Query: 470 RQIFINLISNAINYTQDGGSXXXXXXXGQKADGTETVVFTVRDTGMGIPRKDLPRIFERF 529 RQI +NL++NAI YT D G + + V DTG+GI KDLPRIFERF Sbjct: 483 RQILLNLVTNAIAYTPDKGRIEISLIERENE-----LDLIVSDTGIGISEKDLPRIFERF 537 Query: 530 YRVDKAXXXXXXXXXXXXXIVKHLVELHHGSISVESDLGIGSSFILELPLLQDEP 584 YRVDKA IVKHLVE +HG I VES+ G GS+FI+ LP Q P Sbjct: 538 YRVDKARSRQSGGTGLGLAIVKHLVESYHGKIRVESEEGKGSTFIVTLPRTQTRP 592 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.134 0.366 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,062,072,691 Number of extensions: 120008530 Number of successful extensions: 497790 Number of sequences better than 1.0e-05: 26832 Number of HSP's gapped: 444224 Number of HSP's successfully gapped: 27235 Length of query: 585 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 444 Effective length of database: 1,732,333,088 Effective search space: 769155891072 Effective search space used: 769155891072 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 134 (56.2 bits)