BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0271.0006.p (890 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KBR1.1 B3KBR1_9BACI DNA polymerase I EC=2.7.7.7 1374 0.0 B1D704.1 B1D704_9BACL DNA polymerase I EC=2.7.7.7 1142 0.0 C0Z7Y9.1 C0Z7Y9_BREBN DNA polymerase I EC=2.7.7.7 994 0.0 Q2B2H6.1 Q2B2H6_9BACI DNA polymerase I EC=2.7.7.7 965 0.0 B7GGU2.1 B7GGU2_ANOFW DNA polymerase I EC=2.7.7.7 964 0.0 >B3KBR1.1 B3KBR1_9BACI DNA polymerase I EC=2.7.7.7 Length = 886 Score = 1374 bits (3557), Expect = 0.0, Method: Compositional matrix adjust. Identities = 676/890 (75%), Positives = 765/890 (85%), Gaps = 4/890 (0%) Query: 1 VDKLILIDGNNIIYRAFFAMPPLTNTAGQQTNAVYGFTTMLLRLIEEHKPTHMIVAFDAG 60 +DKLILIDGNNIIYRAFFAMPPLTN +GQQTNAVYGFTTMLLRLIEEHKPTHM+VAFDAG Sbjct: 1 MDKLILIDGNNIIYRAFFAMPPLTNASGQQTNAVYGFTTMLLRLIEEHKPTHMMVAFDAG 60 Query: 61 KITFRHEGYEDYKGGRQKTPPELSEQFPMLKDLLRNLGVPQFEIDGYEADDIIGSISREA 120 K TFRH +++YKGGRQKTPPELS QFP+LK+LL+ LGV QFEI GYEADDIIG+I+R+A Sbjct: 61 KETFRHADFQEYKGGRQKTPPELSGQFPLLKELLKGLGVSQFEIGGYEADDIIGTITRQA 120 Query: 121 DEAGRQVMIVSGDKDMLQLASEHTTVALVRKGVTEVEMYGPRQIREKYDLTPQQIIDLKG 180 DEAGR+VM+VSGDKDMLQLASEHTT+A+VRKGVTE+E YGP QI+E+Y+LTP QIIDLKG Sbjct: 121 DEAGRKVMVVSGDKDMLQLASEHTTIAMVRKGVTEIEYYGPEQIKERYNLTPDQIIDLKG 180 Query: 181 LMGDASDNIPGVPGVGEKTALKLLQQFGSVEGVLAGTDXXXXXXXXXXXXHADSAIMSKK 240 LMGDASDNIPGVPGVGEKTALKLL +FGSVE V++ TD HADSAI+SKK Sbjct: 181 LMGDASDNIPGVPGVGEKTALKLLHEFGSVEAVVSRTDELKGKMKEKIEEHADSAILSKK 240 Query: 241 LATIYREVPLEHAWEDMVFTGIRSDTAGPALAKLEFKSLLERLSLSAYXXXXXXXXXXXX 300 LATI+REVPLE + ++M FTG+ +TAGPALAKLEFKSL+ERL+LS Sbjct: 241 LATIFREVPLEQSLDEMAFTGLNEETAGPALAKLEFKSLIERLNLSTSGAPGDAAESKPE 300 Query: 301 XXXXXVLDITIVHEAELPDLIAALPGISALHVESNGENPHRAEVIGLGLSSPEQHYFVPF 360 +D+T+V + ++ L ++ LHVE++G+NPH A+VIGL L++ E+ YF+PF Sbjct: 301 AK----IDVTLVDATGIAEVADHLAQVTVLHVETHGDNPHHADVIGLALATEERQYFLPF 356 Query: 361 ELLKSPAAEKLRDWLEDEKAPKSGYDLHRADLALHWQGIAFAGAANDVQLAAYLLDPTEA 420 ++LKS AE +R WL D + PK GYDLHR DLALHWQGIAFAGAA DV LAAYLLDPTE+ Sbjct: 357 DVLKSEEAEPVRAWLADSEIPKRGYDLHRIDLALHWQGIAFAGAAFDVHLAAYLLDPTES 416 Query: 421 NQNLYDLTAKYGLPRLSPDEEVFGKGAKYKIPELEILGNHIARKSAAVLGIVQKQQQELT 480 NQ L L +KYGL L DE+VFGKGAKYK+P++E L H+ARK AV +V Q++EL Sbjct: 417 NQTLSGLASKYGLAYLQADEDVFGKGAKYKVPDVEKLSEHMARKCLAVSELVPIQEKELA 476 Query: 481 DTDMTGLFVDLEMPLSRILADMEKQGIAVNKEDLIDLGKEFEAQISRLAADIYAICGTEF 540 +M LF DLEMPLSRILADMEKQGIAVN EDL +LG+EFE QI++L +IY I GTEF Sbjct: 477 ANEMLPLFHDLEMPLSRILADMEKQGIAVNAEDLKELGREFEGQIAKLVQEIYEIAGTEF 536 Query: 541 NLNSPKQLGEILFVKLGLPVVKKTKTGYSTDAEVLEKLAPYHDAVRLILQYRTIAKLQST 600 NLNSPKQLGEILFVKL LPV+KKTKTGYSTDAEVLEKLAPYHD VRLILQYRT+AKLQST Sbjct: 537 NLNSPKQLGEILFVKLELPVIKKTKTGYSTDAEVLEKLAPYHDIVRLILQYRTLAKLQST 596 Query: 601 YVEGLLKEISPDTGKVHTFYRQTIAATGRLSSQFPNLQNIPIRLEEGRKIRKIFVPSEPG 660 YVEGLLKEIS TGKVHT+YRQTIAATGRLSSQ+PNLQNIPIRLEEGRK+RK+FVPSEPG Sbjct: 597 YVEGLLKEISSVTGKVHTYYRQTIAATGRLSSQYPNLQNIPIRLEEGRKLRKVFVPSEPG 656 Query: 661 WSILAADYSQIELRVLAHISGDERMKEAFVEDMDIHTKTAMDVFGVSADQVDSNMRRSAK 720 WSILAADYSQIELRVLAHIS DER+KEAFV DMDIHTKTAMDVFGV D+VDSNMRRSAK Sbjct: 657 WSILAADYSQIELRVLAHISDDERLKEAFVHDMDIHTKTAMDVFGVGMDEVDSNMRRSAK 716 Query: 721 AVNFGIVYGISDYGLSQNLNISRKEASQFIEQYFEVFKGVRRYMDEIVVEARKQGYVTTL 780 AVNFGIVYGISDYGLSQNLNI+RKEA+ FI+QYFEVF+GVRRYMD IV +A++ GYV TL Sbjct: 717 AVNFGIVYGISDYGLSQNLNITRKEAAAFIDQYFEVFQGVRRYMDVIVKQAKQDGYVKTL 776 Query: 781 LERRRYLPEINAKNFNLRSFAERTAMNTPIQGTAADIIKLAMVHMDKALHERGLRSRMLL 840 LERRRYLPEINA NFNLRSFAERTAMNTPIQGTAADIIKLAMVHMDKALHER L+SRMLL Sbjct: 777 LERRRYLPEINASNFNLRSFAERTAMNTPIQGTAADIIKLAMVHMDKALHERQLKSRMLL 836 Query: 841 QVHDELVFEVPEDELELMKTLLPEVMAGALKLSVPLKAEVSYGSNWYEAK 890 QVHDELVFEVPEDELE+MK L+P+VM+ ALKLSVPLK+EVSYG NWYEAK Sbjct: 837 QVHDELVFEVPEDELEVMKELVPDVMSQALKLSVPLKSEVSYGENWYEAK 886 >B1D704.1 B1D704_9BACL DNA polymerase I EC=2.7.7.7 Length = 855 Score = 1142 bits (2953), Expect = 0.0, Method: Compositional matrix adjust. Identities = 560/854 (65%), Positives = 673/854 (78%), Gaps = 2/854 (0%) Query: 1 VDKLILIDGNNIIYRAFFAMPPLTNTAGQQTNAVYGFTTMLLRLIEEHKPTHMIVAFDAG 60 +DK ILIDGN+I RAF+AMPPLTN+AG TNAV+GFTTMLL+L+E+ KPTH++VAFDAG Sbjct: 1 MDKWILIDGNSIANRAFYAMPPLTNSAGLHTNAVFGFTTMLLKLLEDEKPTHVLVAFDAG 60 Query: 61 KITFRHEGYEDYKGGRQKTPPELSEQFPMLKDLLRNLGVPQFEIDGYEADDIIGSISREA 120 K+ FRHEGY +YKGGR KTP ELSEQFP++KDLL+ G+ QFE+ GYEADDIIG+++R A Sbjct: 61 KVVFRHEGYTEYKGGRAKTPSELSEQFPVMKDLLKAFGISQFELSGYEADDIIGTLTRLA 120 Query: 121 DEAGRQVMIVSGDKDMLQLASEHTTVALVRKGVTEVEMYGPRQIREKYDLTPQQIIDLKG 180 DE + ++V+GDKDMLQLAS++ T+A+ RKG++EVE + P I EKY L P QIIDLKG Sbjct: 121 DEQKVETLVVTGDKDMLQLASDNVTIAITRKGISEVEHFSPAAIDEKYGLKPMQIIDLKG 180 Query: 181 LMGDASDNIPGVPGVGEKTALKLLQQFGSVEGVLAGTDXXXXXXXXXXXXHADSAIMSKK 240 LMGDASDNIPG+PGVGEKTALK+L +FG+VE VLA T+ H D AIMSKK Sbjct: 181 LMGDASDNIPGIPGVGEKTALKMLHEFGTVEEVLANTESLKGKMKEKVETHKDDAIMSKK 240 Query: 241 LATIYREVPLEHAWEDMVFTGIRSDTAGPALAKLEFKSLLERLSLSAYXXXXXXXXXXXX 300 LATI+REVPLEH+ ED+ + G + T A KLEFKSL+ERL L+ Sbjct: 241 LATIFREVPLEHSAEDIRYEGYQPATLADAFRKLEFKSLIERLDLNGAGAGSNESAAPAV 300 Query: 301 XXXXXVLDITIVHEAELPDLIAALPGIS-ALHVESNGENPHRAEVIGLGLSSPEQHYFVP 359 V++ EA L D+++AL G L+VE+ GENPH+AEV+GL + + Y VP Sbjct: 301 ELNIVVIESDNDGEA-LKDMLSALQGTEHGLYVEAIGENPHQAEVLGLAAAVGDTAYVVP 359 Query: 360 FELLKSPAAEKLRDWLEDEKAPKSGYDLHRADLALHWQGIAFAGAANDVQLAAYLLDPTE 419 L+ P +LR WLED PK+G+D H+ +LAL W+GI + GAA DVQLAAYLLDPT+ Sbjct: 360 VAALQQPFTAELRKWLEDADKPKNGFDTHKIELALGWRGIEWHGAAFDVQLAAYLLDPTD 419 Query: 420 ANQNLYDLTAKYGLPRLSPDEEVFGKGAKYKIPELEILGNHIARKSAAVLGIVQKQQQEL 479 N L L +YG + DE V+GKGAK+K+P+ E L H++ K+ AV + + +L Sbjct: 420 TNLTLNALCDRYGQSSVPHDEAVYGKGAKFKVPDNETLHRHLSAKADAVRKLTSLMRADL 479 Query: 480 TDTDMTGLFVDLEMPLSRILADMEKQGIAVNKEDLIDLGKEFEAQISRLAADIYAICGTE 539 M L+ +LE PLS ILA ME+QGI V K +L LG E E ++S ++IY + E Sbjct: 480 EKRGMNELYFELEQPLSVILAGMERQGIKVEKAELERLGSELETKLSAAVSEIYRLAEME 539 Query: 540 FNLNSPKQLGEILFVKLGLPVVKKTKTGYSTDAEVLEKLAPYHDAVRLILQYRTIAKLQS 599 FN+ SPKQLGE+LF KLGLPV KKTKTGYSTDAEVLEKLAPYH+ V LIL YRT++KLQS Sbjct: 540 FNIGSPKQLGEVLFEKLGLPVQKKTKTGYSTDAEVLEKLAPYHEIVPLILHYRTLSKLQS 599 Query: 600 TYVEGLLKEISPDTGKVHTFYRQTIAATGRLSSQFPNLQNIPIRLEEGRKIRKIFVPSEP 659 TY+EGLLKE+ P+TGK+HT+YRQTIAATGRLSSQFPNLQNIPIRLEEGR+IRK FVPSEP Sbjct: 600 TYIEGLLKEVRPETGKIHTYYRQTIAATGRLSSQFPNLQNIPIRLEEGRQIRKAFVPSEP 659 Query: 660 GWSILAADYSQIELRVLAHISGDERMKEAFVEDMDIHTKTAMDVFGVSADQVDSNMRRSA 719 GW ILAADYSQIELRVLAHISGDER+KEAF+ DMDIHTKTAMDVFGVSADQVDSNMRRSA Sbjct: 660 GWYILAADYSQIELRVLAHISGDERLKEAFIHDMDIHTKTAMDVFGVSADQVDSNMRRSA 719 Query: 720 KAVNFGIVYGISDYGLSQNLNISRKEASQFIEQYFEVFKGVRRYMDEIVVEARKQGYVTT 779 KAVNFGIVYGISD+GLSQNLNI+RKEA++FIEQYFEVF+GVR+YMD+IV++AR+ G+VTT Sbjct: 720 KAVNFGIVYGISDFGLSQNLNITRKEAAKFIEQYFEVFQGVRKYMDDIVMQARRDGFVTT 779 Query: 780 LLERRRYLPEINAKNFNLRSFAERTAMNTPIQGTAADIIKLAMVHMDKALHERGLRSRML 839 LLERRRYLP+I A NFNLRSFAERTAMNTPIQGTAADIIKLAMV M++ L ERGL+SRML Sbjct: 780 LLERRRYLPDIKASNFNLRSFAERTAMNTPIQGTAADIIKLAMVRMNETLRERGLKSRML 839 Query: 840 LQVHDELVFEVPED 853 LQVHDELVFEVPE+ Sbjct: 840 LQVHDELVFEVPEE 853 >C0Z7Y9.1 C0Z7Y9_BREBN DNA polymerase I EC=2.7.7.7 Length = 882 Score = 994 bits (2570), Expect = 0.0, Method: Compositional matrix adjust. Identities = 498/888 (56%), Positives = 635/888 (71%), Gaps = 10/888 (1%) Query: 4 LILIDGNNIIYRAFFAMPPLTNTAGQQTNAVYGFTTMLLRLIEEHKPTHMIVAFDAGKIT 63 +LIDGN++ RAF+A+P L+ +AG TNAV GFTTMLL+++EE KPTH++VAFDAGK+ Sbjct: 4 FVLIDGNSVANRAFYALPLLSTSAGLHTNAVLGFTTMLLKVLEEMKPTHIMVAFDAGKVV 63 Query: 64 FRHEGYEDYKGGRQKTPPELSEQFPMLKDLLRNLGVPQFEIDGYEADDIIGSISREADEA 123 FRH Y +YKGGR KTPPELSEQFP++++LL + +FE++GYEADDIIG+++++ADE Sbjct: 64 FRHSEYAEYKGGRSKTPPELSEQFPLIRELLDAFSIKRFELEGYEADDIIGTLTKQADEQ 123 Query: 124 GRQVMIVSGDKDMLQLASEHTTVALVRKGVTEVEMYGPRQIREKYDLTPQQIIDLKGLMG 183 + +++GDKDMLQL SEH +VAL RKGV+E+EMY P +I EKY L P QIIDLKGLMG Sbjct: 124 AWKTTVITGDKDMLQLVSEHVSVALTRKGVSEIEMYTPEEIHEKYGLKPLQIIDLKGLMG 183 Query: 184 DASDNIPGVPGVGEKTALKLLQQFGSVEGVLAGTDXXX-XXXXXXXXXHADSAIMSKKLA 242 D+SDNIPGVPGVGEKTALKLL ++GSVE VL D + D A MSK LA Sbjct: 184 DSSDNIPGVPGVGEKTALKLLHEYGSVEQVLENIDKVSGKKLQENLRENVDKANMSKALA 243 Query: 243 TIYREVPLEHAWEDMVFTGIRSDTAGPALAKLEFKSLLERLSLSAYXXXXXXXXXXXXXX 302 TI RE P+E ++ F G K+EFKSLL ++ ++ Sbjct: 244 TILREAPVELDVQETGFEGYDGLPVSEFFKKMEFKSLLSKIKVA-------QPEGGSGQA 296 Query: 303 XXXVLDITIVHEAELPDLIAALPGISALHVESNGENPHRAEVIGLGLSSPEQHYFVPFEL 362 ++ E + L AL++E +GEN H A +G+GL++ + FVP+++ Sbjct: 297 DAKPFSFEMISEENKAAYESKLTSPMALYIEMDGENYHHAPFLGIGLATEDTVMFVPWDV 356 Query: 363 LKSPAAEKLRDWLEDEKAPKSGYDLHRADLALHWQGIAFAGAANDVQLAAYLLDPTEANQ 422 K A L +WL D K +D R + L W A G + DV LA+YLL+ E+N Sbjct: 357 AKEWKA--LCEWLADPAKEKWVFDGKRDTVGLAWHDFAIKGISFDVYLASYLLNAAESNP 414 Query: 423 NLYDLTAKYGLPRLSPDEEVFGKGAKYKIPELEILGNHIARKSAAVLGIVQKQQQELTDT 482 L + A+Y R+ DEEV+GKGAK +PE+++L H+A K+AA+ V +++L + Sbjct: 415 TLDSIAAQYAQTRVLSDEEVYGKGAKRLVPEMDVLSEHVAHKAAAIWQSVPVLREQLAEN 474 Query: 483 DMTGLFVDLEMPLSRILADMEKQGIAVNKEDLIDLGKEFEAQISRLAADIYAICGTEFNL 542 +M L +LE PLS +LA MEKQG+ VN E L+ +G++ + +++ L IY + G FN+ Sbjct: 475 EMEKLLGELEAPLSMVLALMEKQGVKVNSERLVQMGEDLDKKLAGLTDQIYELAGGAFNI 534 Query: 543 NSPKQLGEILFVKLGLPVVKKTKTGYSTDAEVLEKLAPYHDAVRLILQYRTIAKLQSTYV 602 NSPKQLGEILF +L LPV+KKTKTG ST A+VLEKLAPYH + IL +R + KL+STY+ Sbjct: 535 NSPKQLGEILFDRLSLPVLKKTKTGPSTSADVLEKLAPYHPIIDAILTFRQLGKLRSTYI 594 Query: 603 EGLLKEISPDTGKVHTFYRQTIAATGRLSSQFPNLQNIPIRLEEGRKIRKIFVPSEPGWS 662 EGL KEI T KVHT Y Q ATGRLSS PNLQNIPIR+EEGRKIR+ F+PSE GW Sbjct: 595 EGLTKEIHTKTSKVHTLYNQATTATGRLSSTDPNLQNIPIRMEEGRKIREAFIPSEDGWY 654 Query: 663 ILAADYSQIELRVLAHISGDERMKEAFVEDMDIHTKTAMDVFGVSADQVDSNMRRSAKAV 722 +LAADYSQIELR+LAHIS DE + +AF + MDIHT+TAMDVFGVS ++V S MRR AKAV Sbjct: 655 MLAADYSQIELRILAHISQDENLIDAFQKGMDIHTRTAMDVFGVSEEEVTSLMRRQAKAV 714 Query: 723 NFGIVYGISDYGLSQNLNISRKEASQFIEQYFEVFKGVRRYMDEIVVEARKQGYVTTLLE 782 NFGIVYGISDYGLSQNLNI+RKEA FIE+YF+VF GV+R+MDEIV +A+ G+VTTLL Sbjct: 715 NFGIVYGISDYGLSQNLNITRKEAGDFIERYFDVFSGVKRWMDEIVQQAKADGHVTTLLN 774 Query: 783 RRRYLPEINAKNFNLRSFAERTAMNTPIQGTAADIIKLAMVHMDKALHERGLRSRMLLQV 842 RRRYLP+I + NFNLRSFAERTAMNTPIQGTAAD+IKLAM+ M +AL E+GL SRMLLQV Sbjct: 775 RRRYLPDIRSSNFNLRSFAERTAMNTPIQGTAADVIKLAMIRMQEALEEKGLASRMLLQV 834 Query: 843 HDELVFEVPEDELELMKTLLPEVMAGALKLSVPLKAEVSYGSNWYEAK 890 HDELVFEVP++ELE+M+ L+PEVM AL L VPLK +VS G WY+AK Sbjct: 835 HDELVFEVPDNELEVMRKLVPEVMESALSLDVPLKVDVSDGRTWYDAK 882 >Q2B2H6.1 Q2B2H6_9BACI DNA polymerase I EC=2.7.7.7 Length = 877 Score = 965 bits (2495), Expect = 0.0, Method: Compositional matrix adjust. Identities = 484/889 (54%), Positives = 623/889 (70%), Gaps = 16/889 (1%) Query: 3 KLILIDGNNIIYRAFFAMPPLTNTAGQQTNAVYGFTTMLLRLIEEHKPTHMIVAFDAGKI 62 KL+LIDGN+I YRAFFA+P L N G TNAVYGFT ML+R++E+ P+H++VAFDAGK Sbjct: 4 KLVLIDGNSIAYRAFFALPLLNNDKGIHTNAVYGFTMMLMRILEDEDPSHILVAFDAGKT 63 Query: 63 TFRHEGYEDYKGGRQKTPPELSEQFPMLKDLLRNLGVPQFEIDGYEADDIIGSISREADE 122 TFRH+ + +YKGGRQKTPPELSEQFP ++DLL +P++E++ YEADDIIG++S +A++ Sbjct: 64 TFRHKTFTEYKGGRQKTPPELSEQFPFIRDLLDAYQIPRYELENYEADDIIGTLSLQAEQ 123 Query: 123 AGRQVMIVSGDKDMLQLASEHTTVALVRKGVTEVEMYGPRQIREKYDLTPQQIIDLKGLM 182 G +V ++SGDKD+ QL+SEHTTV + RKG+T++E Y P IREKY L+P QIID+KGLM Sbjct: 124 EGFEVKVISGDKDLTQLSSEHTTVGITRKGITDIEEYTPEHIREKYGLSPGQIIDMKGLM 183 Query: 183 GDASDNIPGVPGVGEKTALKLLQQFGSVEGVLAGTDXXX-XXXXXXXXXHADSAIMSKKL 241 GD+SDNIPGVPGVGEKTA+KLL++F ++E +L D H D A+MSK+L Sbjct: 184 GDSSDNIPGVPGVGEKTAIKLLKEFETLENLLGSIDRVSGQKLKEKLEEHKDLAVMSKEL 243 Query: 242 ATIYREVPLEHAWEDMVFTGIRSDTAGPALAKLEFKSLLERLSLSAYXXXXXXXXXXXXX 301 ATI RE P+E ED+ ++G L F SLLE++ Sbjct: 244 ATITREAPVEVKVEDVGYSGYDQAKVVSLFKDLGFNSLLEKIGGELPEETAAPLEDIQFE 303 Query: 302 XXXXVLDITIVHEAELPDLIAALPGISALHVESNGENPHRAEVIGLGLSSPEQHYFVPFE 361 +LD E +A +VE EN H AE+ G +S YF+P E Sbjct: 304 TAENILDDLFADE-------------TAFYVEMLEENYHTAEIAGFSAASGNGVYFIPAE 350 Query: 362 LLKSPAAEKLRDWLEDEKAPKSGYDLHRADLALHWQGIAFAGAANDVQLAAYLLDPTEAN 421 L S +E + W EDE K YD R +++L GI G D+ +A+Y+++P+E+ Sbjct: 351 LALS--SETFKKWAEDESKKKIVYDAKRTEVSLRHHGIHLKGVEFDLLIASYIINPSESI 408 Query: 422 QNLYDLTAKYGLPRLSPDEEVFGKGAKYKIPELEILGNHIARKSAAVLGIVQKQQQELTD 481 ++ + ++G + D+ V+GKGAK KIP E L H+ARK+AA+ + K + EL + Sbjct: 409 EDFASVAKRHGYNGVQTDDAVYGKGAKRKIPAQEELAGHLARKAAALEALRDKLEDELKE 468 Query: 482 TDMTGLFVDLEMPLSRILADMEKQGIAVNKEDLIDLGKEFEAQISRLAADIYAICGTEFN 541 LF DLEMPLS ILADME QG+ V+ E L +G++ ++ + I+ + G FN Sbjct: 469 NRQYELFYDLEMPLSLILADMESQGVKVDLERLQAMGEQINQKLGDIEERIHELAGEAFN 528 Query: 542 LNSPKQLGEILFVKLGLPVVKKTKTGYSTDAEVLEKLAPYHDAVRLILQYRTIAKLQSTY 601 +NSPKQLG ILF KLGLP VKKTKTGYST A+VLEKL H+ +R ILQYR + KLQSTY Sbjct: 529 INSPKQLGVILFEKLGLPPVKKTKTGYSTSADVLEKLEDKHEIIREILQYRQLGKLQSTY 588 Query: 602 VEGLLKEISPDTGKVHTFYRQTIAATGRLSSQFPNLQNIPIRLEEGRKIRKIFVPSEPGW 661 +EGLLK TGKVHT + Q + TGRLSS PNLQNIPIRLEEGRKIR+ FVPSE GW Sbjct: 589 IEGLLKVTDKKTGKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEKGW 648 Query: 662 SILAADYSQIELRVLAHISGDERMKEAFVEDMDIHTKTAMDVFGVSADQVDSNMRRSAKA 721 I AADYSQIELRVLAHI+GDE++ EAF ED D+HTKTAM+VF VS +V SNMRR AKA Sbjct: 649 VIFAADYSQIELRVLAHIAGDEKLIEAFREDQDVHTKTAMEVFHVSEGEVTSNMRRHAKA 708 Query: 722 VNFGIVYGISDYGLSQNLNISRKEASQFIEQYFEVFKGVRRYMDEIVVEARKQGYVTTLL 781 VNFGIVYGISDYGLSQ+L I+RKEA QFI++Y E + GVR YMD+I+ EA+++GYV+TLL Sbjct: 709 VNFGIVYGISDYGLSQSLGITRKEAGQFIDRYLESYPGVREYMDDIIQEAKQKGYVSTLL 768 Query: 782 ERRRYLPEINAKNFNLRSFAERTAMNTPIQGTAADIIKLAMVHMDKALHERGLRSRMLLQ 841 RRRYLPEI ++NFNLRSFAERTAMNTPIQG+AAD+IK AM+ M L E GL+SR+LL Sbjct: 769 HRRRYLPEITSRNFNLRSFAERTAMNTPIQGSAADVIKKAMIDMADRLREEGLQSRLLLS 828 Query: 842 VHDELVFEVPEDELELMKTLLPEVMAGALKLSVPLKAEVSYGSNWYEAK 890 VHDEL+FE PE+E+E++K ++P+VM + L VPLK + SYG W++AK Sbjct: 829 VHDELIFEAPEEEIEILKRIVPDVMENTVDLDVPLKVDFSYGPTWFDAK 877 >B7GGU2.1 B7GGU2_ANOFW DNA polymerase I EC=2.7.7.7 Length = 875 Score = 964 bits (2493), Expect = 0.0, Method: Compositional matrix adjust. Identities = 478/890 (53%), Positives = 634/890 (71%), Gaps = 18/890 (2%) Query: 2 DKLILIDGNNIIYRAFFAMPPLTNTAGQQTNAVYGFTTMLLRLIEEHKPTHMIVAFDAGK 61 +KL+LIDGN+I YRAFFA+P L N G TNA+YGFT ML++LIEE KPTH++VAFDAGK Sbjct: 3 NKLVLIDGNSIAYRAFFALPLLHNDKGIHTNAIYGFTMMLMKLIEEEKPTHILVAFDAGK 62 Query: 62 ITFRHEGYEDYKGGRQKTPPELSEQFPMLKDLLRNLGVPQFEIDGYEADDIIGSISREAD 121 TFRHE Y +YKGGRQKTPPELSEQFP L++LL + +E++ YEADDIIG+++ +A+ Sbjct: 63 TTFRHEVYTEYKGGRQKTPPELSEQFPFLRELLDAYNIRTYELENYEADDIIGTLATKAE 122 Query: 122 EAGRQVMIVSGDKDMLQLASEHTTVALVRKGVTEVEMYGPRQIREKYDLTPQQIIDLKGL 181 + G V+I+SGD+D+ QLASE V + +KG+T++E Y P+ + EKY LTP QI+DLKGL Sbjct: 123 KEGFDVVIISGDRDLTQLASERIHVHVTKKGITDMERYTPKHVLEKYGLTPAQIVDLKGL 182 Query: 182 MGDASDNIPGVPGVGEKTALKLLQQFGSVEGVLAGTDXXX-XXXXXXXXXHADSAIMSKK 240 MGDASDNIPGVPGVGEKTALKLL+++G+VE VLA + + + A++SK+ Sbjct: 183 MGDASDNIPGVPGVGEKTALKLLKEYGTVEHVLASLEHISGKKLKENLQTYHEQALLSKQ 242 Query: 241 LATIYREVPLEHAWEDMVFTGIRSDTAGPALAKLEFKSLLERLSLSAYXXXXXXXXXXXX 300 LATI R+VPL + +++ + ++ +L F SL++++ S+ Sbjct: 243 LATIRRDVPLTLSLDELAWHSYDAERVAALFQELGFTSLMDKIGQSS------------- 289 Query: 301 XXXXXVLDITIVHEAELPDLIAALPGISALHVESNGENPHRAEVIGLGLSSPEQHYFVPF 360 + DI+ V + + + G AL VE EN H+A ++G L + H+F+P Sbjct: 290 QEQLSLTDISFVTVQTIDEHMLTKEG--ALVVEVLDENYHQAPIVGFALVNERGHFFIPT 347 Query: 361 ELLKSPAAEKLRDWLEDEKAPKSGYDLHRADLALHWQGIAFAGAANDVQLAAYLLDPTEA 420 ++ + A+ + + WLEDE+ KS +D RA +AL W GI G D+ LAAYLL+PT+A Sbjct: 348 DI--ALASSRFKRWLEDEQCKKSVFDAKRAIVALKWNGIELKGVDFDLLLAAYLLNPTDA 405 Query: 421 NQNLYDLTAKYGLPRLSPDEEVFGKGAKYKIPELEILGNHIARKSAAVLGIVQKQQQELT 480 N ++ + + DEEV+GKGAK IP +L H+ RK+ A+ + + QEL Sbjct: 406 NGDVAAVAKTKQYTDVQSDEEVYGKGAKQAIPPTNVLAEHLVRKAKAIASLKETYIQELK 465 Query: 481 DTDMTGLFVDLEMPLSRILADMEKQGIAVNKEDLIDLGKEFEAQISRLAADIYAICGTEF 540 + L V LE+PL+ ILA ME G+ V+ + L +GKEF AQ+ ++ IY + GT F Sbjct: 466 RNEQFELLVHLELPLTFILAQMEFYGVKVDVDRLEQMGKEFTAQLEQIEQRIYELAGTTF 525 Query: 541 NLNSPKQLGEILFVKLGLPVVKKTKTGYSTDAEVLEKLAPYHDAVRLILQYRTIAKLQST 600 N+NSPKQLG ILF KL LP+VKKTKTGYST A+VLEKLAPYH+ + IL YR + KLQST Sbjct: 526 NINSPKQLGTILFEKLQLPIVKKTKTGYSTSADVLEKLAPYHEIIEQILHYRQLGKLQST 585 Query: 601 YVEGLLKEISPDTGKVHTFYRQTIAATGRLSSQFPNLQNIPIRLEEGRKIRKIFVPSEPG 660 YVEGL+K + DTGKVHT ++Q + TGRLSS PNLQNIPIR+EEGRKIR+ FVPS Sbjct: 586 YVEGLMKVVRKDTGKVHTIFQQALTQTGRLSSTEPNLQNIPIRIEEGRKIRQAFVPSSDD 645 Query: 661 WSILAADYSQIELRVLAHISGDERMKEAFVEDMDIHTKTAMDVFGVSADQVDSNMRRSAK 720 W I AADYSQIELRVLAHI+ DE + AF D+DIHTKTAMD+F V D+V ++MRR AK Sbjct: 646 WVIFAADYSQIELRVLAHIANDENLIAAFHHDLDIHTKTAMDIFHVKEDEVTAHMRRQAK 705 Query: 721 AVNFGIVYGISDYGLSQNLNISRKEASQFIEQYFEVFKGVRRYMDEIVVEARKQGYVTTL 780 AVNFGIVYGISDYGLSQNL I+RKEA++FIE+YF + GV+RYM+E+V +A+++GYVTTL Sbjct: 706 AVNFGIVYGISDYGLSQNLGITRKEAAEFIERYFRSYPGVKRYMEEVVQDAKQKGYVTTL 765 Query: 781 LERRRYLPEINAKNFNLRSFAERTAMNTPIQGTAADIIKLAMVHMDKALHERGLRSRMLL 840 L RRRYLP+I + NFN+RSFAERTAMNTPIQG+AADIIK AM+ + LHE L++R+LL Sbjct: 766 LHRRRYLPDITSGNFNVRSFAERTAMNTPIQGSAADIIKKAMIDLANRLHEERLQTRLLL 825 Query: 841 QVHDELVFEVPEDELELMKTLLPEVMAGALKLSVPLKAEVSYGSNWYEAK 890 QVHDEL+ E P++E+EL+K ++P+VM A+ L VPLK + +G WY+AK Sbjct: 826 QVHDELILEAPKEEIELLKKIVPDVMENAVSLRVPLKVDYHFGPTWYDAK 875 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.136 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 4,968,904,463 Number of extensions: 205564118 Number of successful extensions: 528173 Number of sequences better than 1.0e-05: 2703 Number of HSP's gapped: 518093 Number of HSP's successfully gapped: 3819 Length of query: 890 Length of database: 3,060,696,203 Length adjustment: 145 Effective length of query: 745 Effective length of database: 1,694,649,028 Effective search space: 1262513525860 Effective search space used: 1262513525860 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 136 (57.0 bits)