BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0269.0011.p (387 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A9KIC4.1 A9KIC4_CLOPH Multi-sensor signal transduction histidine... 283 2e-74 A9AWB2.1 A9AWB2_HERA2 Histidine kinase internal region 268 6e-70 B1D4P2.1 B1D4P2_9BACL Multi-sensor signal transduction histidine... 263 2e-68 A7B0I5.1 A7B0I5_RUMGN Putative uncharacterized protein 262 4e-68 B3KJG0.1 B3KJG0_9BACI Histidine kinase internal region 256 3e-66 >A9KIC4.1 A9KIC4_CLOPH Multi-sensor signal transduction histidine kinase Length = 585 Score = 283 bits (724), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 142/387 (36%), Positives = 233/387 (60%), Gaps = 10/387 (2%) Query: 1 VTIGTTGFFYLLDEQNNPLYVPPVQAGELALVQDNLIPAGEKGRSGSFVLQTGGPPRFIV 60 + +G G+ +LLDE+ N +Y P Q L+ + + E S + L G + V Sbjct: 209 INLGYKGYIFLLDEEGNIIYHPKQQLIYNGLINEKTLEVKECKES--YFLTEGTDRKLYV 266 Query: 61 HTSSLATGWTIIGIAPLQEIVAEANRIRQLIIISVGLSIIFAIXXXXXXXXXXXXPIQLL 120 + S TGWT +G+A + E+ + + ++L +IS ++ A+ PI+ L Sbjct: 267 ISRSEKTGWTAVGVANVSELFLQREQTQRLYLISTVAILLIAMLLSILISRAITKPIKKL 326 Query: 121 QHKMRLTASGYLEAKVKPDGTDEIADLGQSFNIMVEQIKELLAQSIRKQQQLQKAELRTL 180 + M+ G KV+ G+DEIA+LG+S+NIM++ + EL+ ++ Q+Q +K+ELR L Sbjct: 327 RDSMKEVEKGNFHEKVETSGSDEIANLGKSYNIMIQTVDELMEARVKDQEQKRKSELRAL 386 Query: 181 QAQINPHFLYNTLDSIVWMAEAGNHDGVIRLVKALSAFFRLSLNNGRDWIQIRSELAHVQ 240 QAQINPHFLYNTLDSIVWMAE G + V+ + +L+ FR S++N + +R E+ +V+ Sbjct: 387 QAQINPHFLYNTLDSIVWMAEEGKNQEVVTMTASLAKLFRQSISNEAEEFTLRQEVDYVR 446 Query: 241 SYLIIQQMRYHDILEFKLEVAEELQEYPILNMTLQPLVENALYHGIKNKRGMGLIRIGGY 300 +YL+IQ+MRY + L + ++V E + Y ++ + LQPLVENALYHG+K K G+G I + GY Sbjct: 447 NYLVIQKMRYKEQLNYDIQVPESILNYYVIKLILQPLVENALYHGVKYKDGVGTIFVDGY 506 Query: 301 TDGGSIMLTVSDNGIGIPAGRLEILRESIEHPIQSEDTEDTGQGGFGLQNVHQRLRLYFG 360 +++L V D+GIG+ L L E + + T T + ++N+H R++L++G Sbjct: 507 ETESTVVLQVIDDGIGMDEEELSHLFE------KRKSTHKTSR--VAIRNIHNRIQLHYG 558 Query: 361 PEYGIRLDSSEGYGTQITVRIPKNKGV 387 E+G+ +S +GYGT++ + +PK G+ Sbjct: 559 KEFGLSFESKKGYGTKVMITLPKKMGL 585 >A9AWB2.1 A9AWB2_HERA2 Histidine kinase internal region Length = 516 Score = 268 bits (685), Expect = 6e-70, Method: Compositional matrix adjust. Identities = 139/296 (46%), Positives = 195/296 (65%), Gaps = 10/296 (3%) Query: 98 SIIFAIXXXXXXXXXXXXPIQLLQHKMRLTASGYLEAKVKPDGTDEIADLGQSFNIMVEQ 157 SI+F+I PI+ L A LE V D DEI +LG SFNIMV + Sbjct: 214 SILFSIVAAWRISKGIYIPIKKLHDVTTTIARQDLEGLVMADNADEITELGLSFNIMVGK 273 Query: 158 IKELLAQSIRKQQQLQKAELRTLQAQINPHFLYNTLDSIVWMAEAGNHDGVIRLVKALSA 217 IKELL + + + L+KAELR LQAQINPHFLYNTLD+I+WMAEA +I LV ALS Sbjct: 274 IKELLDAKLEEHENLKKAELRVLQAQINPHFLYNTLDAIIWMAEAKRTAQIIDLVSALSR 333 Query: 218 FFRLSLNNGRDWIQIRSELAHVQSYLIIQQMRYHDILEFKLEVAEELQEYPILNMTLQPL 277 FFR++L+ GRDWI + E+AH++SYL IQ++RY DIL++++++ E+ Q +L +TLQPL Sbjct: 334 FFRITLSKGRDWISVPDEIAHIESYLAIQKIRYRDILDYQIDIPEDTQSTEMLKLTLQPL 393 Query: 278 VENALYHGIKNKRGMGLIRI-GGYTDGGSIMLTVSDNGIGIPAGRLEILRESIEHPIQSE 336 VENALYHGIKNKR G I + G + DG + + V DNGIG+ RL+ +R +E + Sbjct: 394 VENALYHGIKNKRSGGTIVVRGRWLDGDRLRIEVEDNGIGMTQERLQQVRTLLE----AG 449 Query: 337 DTEDTG-----QGGFGLQNVHQRLRLYFGPEYGIRLDSSEGYGTQITVRIPKNKGV 387 + TG + G+G+ NV+QR++LY+G +YG+ ++S G GT + + IP+ +G+ Sbjct: 450 NLWVTGVMPIVEDGYGISNVNQRIKLYYGSDYGLSIESEHGRGTCVALIIPRYRGI 505 >B1D4P2.1 B1D4P2_9BACL Multi-sensor signal transduction histidine kinase Length = 596 Score = 263 bits (673), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 151/387 (39%), Positives = 226/387 (58%), Gaps = 12/387 (3%) Query: 1 VTIGTTGFFYLLDEQNNPLYVPPVQAGELALVQDNLIPAGEKGRSGSFVLQTGGPPRFIV 60 + + G+ +++DE N +Y P Q L + + KG SGSF+ G R I Sbjct: 212 IDLSKRGYIFIVDEDGNIVYHPQQQLIYSNLKSEKIDEVLAKG-SGSFMTDEGKTSR-IY 269 Query: 61 HTSSLATGWTIIGIAPLQEIVAEANRIRQLIIISVGL-SIIFAIXXXXXXXXXXXXPIQL 119 GW I+G++ + E++ R QL +++ G+ +I + PI+ Sbjct: 270 TIQDTGFGWKIVGVSYVNELIGN-KREMQLSMVAAGIFCLIVGLLLAVFISRNLSRPIKQ 328 Query: 120 LQHKMRLTASGYLEAKVKPDGTDEIADLGQSFNIMVEQIKELLAQSIRKQQQLQKAELRT 179 LQ M+ G +V EIA L ++FN+MV +I+EL++Q +R+Q+ +K+EL Sbjct: 329 LQEHMKKVEKGIFNIRVPIGNPREIASLARTFNLMVVKIEELMSQVVREQEIKRKSELTA 388 Query: 180 LQAQINPHFLYNTLDSIVWMAEAGNHDGVIRLVKALSAFFRLSLNNGRDWIQIRSELAHV 239 LQAQINPHFLYNTLDSI+WMAE D V+ + AL+ FR S++ G++ + IR+E+ HV Sbjct: 389 LQAQINPHFLYNTLDSIIWMAEGKKTDEVVLMTSALARLFRSSISRGQELVSIRTEIEHV 448 Query: 240 QSYLIIQQMRYHDILEFKLEVAEELQEYPILNMTLQPLVENALYHGIKNKRGMGLIRIGG 299 +YL IQ++RY D L+F ++V ++ Y L + LQPL+ENA+YHGIKN+ G G I++ G Sbjct: 449 ANYLTIQKIRYKDKLDFHIDVDPDIYAYRTLKVLLQPLLENAIYHGIKNRIGTGTIQVTG 508 Query: 300 YTDGGSIMLTVSDNGIGIPAGRLEILRESIEHPIQSEDTEDTGQGGFGLQNVHQRLRLYF 359 G I L VSDNG+G+ A E LR +E P +S D G G+ NVH+R++LYF Sbjct: 509 GKRDGYIWLEVSDNGVGMEA---EALRTILE-PRRS----DRESKGVGVVNVHERIQLYF 560 Query: 360 GPEYGIRLDSSEGYGTQITVRIPKNKG 386 G +YG+ S + GT +TVRI +G Sbjct: 561 GKDYGLTYKSVQDEGTTVTVRIAAIEG 587 >A7B0I5.1 A7B0I5_RUMGN Putative uncharacterized protein Length = 602 Score = 262 bits (670), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 147/396 (37%), Positives = 222/396 (56%), Gaps = 28/396 (7%) Query: 1 VTIGTTGFFYLLDEQNNPLYVPPVQAGELALVQDNLIPAGEK--------GRSGSFV-LQ 51 +IG+ G+ ++LDE+ + +Y P Q LI G K G F+ + Sbjct: 217 TSIGSKGYIFILDEKGSMIYHP----------QQQLIYGGLKEERIEDILASKGDFLETE 266 Query: 52 TGGPPRFIVHTSSLATGWTIIGIAPLQEIVAEANRIRQLIIISVGLSIIFAIXXXXXXXX 111 G + + S TGWT++G + + E++ + + L +++ +I I Sbjct: 267 EGEDSKLYTMSKSEKTGWTVVGASYVTELMKNNRQAQMLYLLAAAGILIGVILISSFISS 326 Query: 112 XXXXPIQLLQHKMRLTASGYLE-AKVKPDGTDEIADLGQSFNIMVEQIKELLAQSIRKQQ 170 P++ L+ M L G E A V+ +EI L +SFN M ++I L+ Q+I +Q+ Sbjct: 327 EITKPLRRLRDSMSLVEKGDFEQASVEITAENEIGSLSKSFNAMTQKIHALMEQNIYEQK 386 Query: 171 QLQKAELRTLQAQINPHFLYNTLDSIVWMAEAGNHDGVIRLVKALSAFFRLSLNNGRDWI 230 Q +K+E++ LQAQINPHFLYNTLDSI+WM+EAG +D V+ + AL+ R S++N R+ I Sbjct: 387 QKRKSEMKALQAQINPHFLYNTLDSIIWMSEAGENDQVVLMTSALAKLLRQSISNDREQI 446 Query: 231 QIRSELAHVQSYLIIQQMRYHDILEFKLEVAEELQEYPILNMTLQPLVENALYHGIKNKR 290 + E+ +V+SYL IQ+MRY D LE+ ++V E + + I+ LQPLVENA+YHG+K K Sbjct: 447 TVAEEIDYVRSYLTIQKMRYKDKLEYTIDVEERILDVRIIKFVLQPLVENAIYHGLKYKE 506 Query: 291 GMGLIRIGGYTDGGSIMLTVSDNGIGIPAGRLEILRESIEHPIQSEDTEDTGQGGFGLQN 350 G + I GY G + L V+D+G G+ LE + E E +S G G+ N Sbjct: 507 TKGNLDIRGYRRGNRVCLVVADDGAGMEESELEHILEKKEKKTKS--------NGVGVYN 558 Query: 351 VHQRLRLYFGPEYGIRLDSSEGYGTQITVRIPKNKG 386 V +RL+LY+GPEYGI S +G GT TV IP + G Sbjct: 559 VQKRLQLYYGPEYGISYISRKGEGTVATVTIPLDGG 594 >B3KJG0.1 B3KJG0_9BACI Histidine kinase internal region Length = 598 Score = 256 bits (654), Expect = 3e-66, Method: Compositional matrix adjust. Identities = 149/384 (38%), Positives = 214/384 (55%), Gaps = 18/384 (4%) Query: 3 IGTTGFFYLLDEQNNPLYVPPVQAGELALVQDNL----IPAGEKGRSGSFVLQTGGPPRF 58 +G G+ +++D + +Y P Q L+ NL + + + GSFV++ G R Sbjct: 214 LGNRGYVFVIDREGRIVYHPQQQ-----LLYSNLKTERLDQVLQDKHGSFVVKEDGASR- 267 Query: 59 IVHTSSLATGWTIIGIAPLQEIVAEANRIRQLIIISVGLSIIFAIXXXXXXXXXXXXPIQ 118 I + GW I+G+ E+V +++ I+ L ++ + PI+ Sbjct: 268 IYSIKNTDFGWKIVGVFYENELVDNKKQMQLSFAIAGLLCLVVGVLFSVVLSRNLTRPIK 327 Query: 119 LLQHKMRLTASGYLEAKVKPDGTDEIADLGQSFNIMVEQIKELLAQSIRKQQQLQKAELR 178 LQ KM G + +V + EI+ L +SFN+MV +IKEL+ Q + +Q+ +K+EL Sbjct: 328 KLQEKMMEVEKGNFDIRVPVGHSREISGLARSFNVMVLKIKELMYQIVVEQEIKRKSELN 387 Query: 179 TLQAQINPHFLYNTLDSIVWMAEAGNHDGVIRLVKALSAFFRLSLNNGRDWIQIRSELAH 238 LQAQINPHFLYNTLDSI+WMAE+ HD VI + AL+ FR SL+ G++ I I +E+ H Sbjct: 388 ALQAQINPHFLYNTLDSIIWMAESKKHDEVILMTSALARLFRASLSKGKELIPIATEVEH 447 Query: 239 VQSYLIIQQMRYHDILEFKLEVAEELQEYPILNMTLQPLVENALYHGIKNKRGMGLIRIG 298 + +YL IQQMRY D + F L++ L Y L + LQPLVENA+YHGIKNK G G I I Sbjct: 448 ITNYLKIQQMRYQDKITFALDIDRGLYPYLTLKVLLQPLVENAIYHGIKNKEGPGTITIT 507 Query: 299 GYTDGGSIMLTVSDNGIGIPAGRLEILRESIEHPIQSEDTEDTGQGGFGLQNVHQRLRLY 358 G I V D+GIG+ ++E L S E + G+ NVHQR++LY Sbjct: 508 GVRRDTRIEFQVKDDGIGMDQSKVETLLTSKEGT--------RSRNSVGIANVHQRIQLY 559 Query: 359 FGPEYGIRLDSSEGYGTQITVRIP 382 FG EYG+ S G GT +T+ IP Sbjct: 560 FGTEYGLSYASVPGSGTSVTLVIP 583 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.139 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,225,401,338 Number of extensions: 91908658 Number of successful extensions: 261772 Number of sequences better than 1.0e-05: 2202 Number of HSP's gapped: 259228 Number of HSP's successfully gapped: 2202 Length of query: 387 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 249 Effective length of database: 1,760,596,133 Effective search space: 438388437117 Effective search space used: 438388437117 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 132 (55.5 bits)