BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0267.0008.p (213 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K8V5.1 B3K8V5_9BACI dTMP kinase EC=2.7.4.9 312 1e-83 C1PDV6.1 C1PDV6_BACCO Thymidylate kinase EC=2.7.4.9 270 6e-71 C0ZHB1.1 C0ZHB1_BREBN Thymidylate kinase EC=2.7.4.9 266 1e-69 A0Q3M5.1 KTHY_CLONN Thymidylate kinase EC=2.7.4.9 261 4e-68 B1DIK3.1 B1DIK3_9BACL dTMP kinase EC=2.7.4.9 260 5e-68 >B3K8V5.1 B3K8V5_9BACI dTMP kinase EC=2.7.4.9 Length = 214 Score = 312 bits (799), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 148/211 (70%), Positives = 179/211 (84%) Query: 3 REGFFITLEGGDGSGKTTVLGRVAAYLQNHSMPYLITREPGGIEIAEKIRSIILDPAHTA 62 R FIT+EGG+GSGKTT++GR+AA++QNHS+PYLITREPGGI+IAEKIRSIILDP HTA Sbjct: 4 RRPLFITVEGGEGSGKTTMMGRLAAFMQNHSIPYLITREPGGIDIAEKIRSIILDPEHTA 63 Query: 63 MDARTEALLYAASRSQHLAEVVEPALKEGLTVLCDRFVDSSLVYQGYARGLGIEEVRSIN 122 MDARTEALLYAA+R QHL E VEPAL++GLTVLCDRFVDSSLVYQGYARGLG+EEV SIN Sbjct: 64 MDARTEALLYAAARRQHLVEKVEPALRQGLTVLCDRFVDSSLVYQGYARGLGMEEVWSIN 123 Query: 123 QFATGGLMPDLTFYLDVDPEVGLSRIAANQDREVNRLDLESMAFHQKVREGYRQVVESDP 182 QFA MPDLT D++P +GLSRIAAN +RE NRLD+E++ FH+KVREGY V E +P Sbjct: 124 QFAIDTRMPDLTLLFDIEPRIGLSRIAANAEREWNRLDMENLTFHEKVREGYLLVAERNP 183 Query: 183 QRIVVLDANRPIHMVEQDIVQTLKDRILKDF 213 RI ++DA++ VE+++ + L+D ILKDF Sbjct: 184 DRIRIVDASKTPAQVEREMNRHLEDAILKDF 214 >C1PDV6.1 C1PDV6_BACCO Thymidylate kinase EC=2.7.4.9 Length = 217 Score = 270 bits (690), Expect = 6e-71, Method: Compositional matrix adjust. Identities = 128/210 (60%), Positives = 166/210 (79%) Query: 4 EGFFITLEGGDGSGKTTVLGRVAAYLQNHSMPYLITREPGGIEIAEKIRSIILDPAHTAM 63 +G FIT EG +G+GKTT+ G +AA+L+ + P ++TREPGGI+IAE+IR IIL+P +T M Sbjct: 2 KGIFITAEGPEGAGKTTITGMIAAHLKENGYPVVLTREPGGIKIAEQIRHIILNPENTEM 61 Query: 64 DARTEALLYAASRSQHLAEVVEPALKEGLTVLCDRFVDSSLVYQGYARGLGIEEVRSINQ 123 DARTEALLYAASR QHLAE V PAL++G VLCDRF+DSSL YQGYARG+GIEEV INQ Sbjct: 62 DARTEALLYAASRRQHLAEKVLPALEQGRIVLCDRFIDSSLAYQGYARGIGIEEVYRINQ 121 Query: 124 FATGGLMPDLTFYLDVDPEVGLSRIAANQDREVNRLDLESMAFHQKVREGYRQVVESDPQ 183 FATGGL+PDLT Y DV+ E GLSRIA N +REVNRLDLE++ FH+KVREG++ +++ P+ Sbjct: 122 FATGGLLPDLTLYFDVEAETGLSRIAKNHNREVNRLDLEAIDFHRKVREGFQILLKRFPE 181 Query: 184 RIVVLDANRPIHMVEQDIVQTLKDRILKDF 213 RI +DAN+ + + +Q + D I + + Sbjct: 182 RIHAIDANKEVEYIYHTALQKVLDAIFRHY 211 >C0ZHB1.1 C0ZHB1_BREBN Thymidylate kinase EC=2.7.4.9 Length = 213 Score = 266 bits (679), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 128/209 (61%), Positives = 161/209 (77%) Query: 1 VAREGFFITLEGGDGSGKTTVLGRVAAYLQNHSMPYLITREPGGIEIAEKIRSIILDPAH 60 ++G FIT+EGG+G+GK+TV+ ++ L+ + L+TREPGGI+IAEKIR IIL+PAH Sbjct: 5 TGKKGRFITIEGGEGAGKSTVIAKLYEELKTRGVDVLLTREPGGIDIAEKIREIILNPAH 64 Query: 61 TAMDARTEALLYAASRSQHLAEVVEPALKEGLTVLCDRFVDSSLVYQGYARGLGIEEVRS 120 T MD RTEALLYAA+R QHLAE V PAL EG VLCDRF+DSSL YQG+ARGLGI+ V Sbjct: 65 TQMDERTEALLYAAARGQHLAEKVLPALAEGKLVLCDRFIDSSLAYQGHARGLGIDAVYQ 124 Query: 121 INQFATGGLMPDLTFYLDVDPEVGLSRIAANQDREVNRLDLESMAFHQKVREGYRQVVES 180 IN+FA G MP+LT + DV PE GL+RI A++ REVNRLDLE M FH+ VREGY+ V+E Sbjct: 125 INRFAVGDCMPELTLFFDVQPETGLARINASRGREVNRLDLEGMRFHELVREGYQLVMER 184 Query: 181 DPQRIVVLDANRPIHMVEQDIVQTLKDRI 209 DP+R VV+DA +P+ V Q +Q L DR+ Sbjct: 185 DPERFVVIDAEQPMEQVYQSALQALLDRL 213 >A0Q3M5.1 KTHY_CLONN Thymidylate kinase EC=2.7.4.9 Length = 205 Score = 261 bits (666), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 122/203 (60%), Positives = 160/203 (78%) Query: 4 EGFFITLEGGDGSGKTTVLGRVAAYLQNHSMPYLITREPGGIEIAEKIRSIILDPAHTAM 63 +G FITLEG +GSGKTT++ + YL +++ Y+ TREPGGI I+E+IR +IL+ + AM Sbjct: 3 KGAFITLEGPEGSGKTTIVKMIEKYLSENNIEYISTREPGGINISEQIRDVILNKDNVAM 62 Query: 64 DARTEALLYAASRSQHLAEVVEPALKEGLTVLCDRFVDSSLVYQGYARGLGIEEVRSINQ 123 DARTEALLY ASR QHLAE V PA+KEG V+CDRF+DSSL YQGYARG+GI+EV +IN+ Sbjct: 63 DARTEALLYVASRRQHLAERVIPAIKEGKVVICDRFIDSSLAYQGYARGIGIDEVMAINE 122 Query: 124 FATGGLMPDLTFYLDVDPEVGLSRIAANQDREVNRLDLESMAFHQKVREGYRQVVESDPQ 183 FA G MPDLT YLD++PEVGL RI+ N +REVNRLDLE++ FH+KVREGY +++E P Sbjct: 123 FAIDGYMPDLTLYLDIEPEVGLKRISKNNEREVNRLDLEALDFHKKVREGYFKLLEKYPN 182 Query: 184 RIVVLDANRPIHMVEQDIVQTLK 206 RI ++AN+P+ V +++ LK Sbjct: 183 RIKKINANQPVDKVFEEVKGFLK 205 >B1DIK3.1 B1DIK3_9BACL dTMP kinase EC=2.7.4.9 Length = 217 Score = 260 bits (665), Expect = 5e-68, Method: Compositional matrix adjust. Identities = 126/205 (61%), Positives = 160/205 (78%) Query: 4 EGFFITLEGGDGSGKTTVLGRVAAYLQNHSMPYLITREPGGIEIAEKIRSIILDPAHTAM 63 +G FIT+EGG+G+GKTT++ ++A +Q + TREPGGI IAE+IRS+ILD HT M Sbjct: 3 KGIFITIEGGEGAGKTTLIEQLAHTMQQRGKTVITTREPGGIPIAEQIRSVILDRNHTGM 62 Query: 64 DARTEALLYAASRSQHLAEVVEPALKEGLTVLCDRFVDSSLVYQGYARGLGIEEVRSINQ 123 DARTEALLYAASR QHL E V PAL +G V+CDRFVDSSL YQG+ARGLG+EEV SIN+ Sbjct: 63 DARTEALLYAASRRQHLVEKVMPALADGQIVICDRFVDSSLAYQGHARGLGMEEVWSINR 122 Query: 124 FATGGLMPDLTFYLDVDPEVGLSRIAANQDREVNRLDLESMAFHQKVREGYRQVVESDPQ 183 FA G MP LT Y+D+DPEVGL+RI A +REVNRLDLES+AFHQ VREGY++++E P+ Sbjct: 123 FAVDGAMPQLTIYMDIDPEVGLARIRAAGEREVNRLDLESLAFHQLVREGYQKLLEQFPE 182 Query: 184 RIVVLDANRPIHMVEQDIVQTLKDR 208 RIV +DA + V ++++ T+ R Sbjct: 183 RIVQIDAGNAANAVLEEVILTIDHR 207 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.138 0.386 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,200,897,903 Number of extensions: 46350685 Number of successful extensions: 227501 Number of sequences better than 1.0e-05: 1494 Number of HSP's gapped: 225283 Number of HSP's successfully gapped: 1494 Length of query: 213 Length of database: 3,060,696,203 Length adjustment: 130 Effective length of query: 83 Effective length of database: 1,835,964,253 Effective search space: 152385032999 Effective search space used: 152385032999 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 128 (53.9 bits)