BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0265.0009.p (417 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KFJ6.1 B3KFJ6_9BACI Histidyl-tRNA synthetase EC=6.1.1.21 626 e-177 B1DIY7.1 B1DIY7_9BACL Histidyl-tRNA synthetase EC=6.1.1.21 592 e-167 A7GT85.1 SYH_BACCN Histidyl-tRNA synthetase EC=6.1.1.21 464 e-129 C3BQD4.1 C3BQD4_9BACI Histidyl-tRNA synthetase 2 459 e-127 C3B8E2.1 C3B8E2_BACMY Histidyl-tRNA synthetase 2 457 e-126 >B3KFJ6.1 B3KFJ6_9BACI Histidyl-tRNA synthetase EC=6.1.1.21 Length = 417 Score = 626 bits (1614), Expect = e-177, Method: Compositional matrix adjust. Identities = 299/412 (72%), Positives = 337/412 (81%) Query: 1 VAKERFEKPTGTQDVLPGAVEKWLVVESKARDLCRRFNYREIRTPMFEHTGLFERGVGET 60 +A E+FEKPTGTQD+LPGAVEKW +E KARDLCRR+NYREIRTP+FE T LFERGVGET Sbjct: 1 MANEKFEKPTGTQDILPGAVEKWQFIEEKARDLCRRYNYREIRTPIFEQTELFERGVGET 60 Query: 61 TDIVEGEMYTFKDKGDRDLALRPEGTAGVVRAYVQNKLYGEPDVSKLYYIGPMFRYERPQ 120 TDIVE EMYTFKDKGDR + LRPEGTAGVVRAYVQNKLYGEPDV+KLYY+GPMFRYERPQ Sbjct: 61 TDIVEKEMYTFKDKGDRSMTLRPEGTAGVVRAYVQNKLYGEPDVTKLYYLGPMFRYERPQ 120 Query: 121 AGRYRQFHQFGIEAFGAVDPAIDAEVVSMGYQFYKDLGLKDVKVELNSVGNAPSRAAYRE 180 AGRYRQFHQFG+E FG DPAIDAEV+++GY FYK+LGL VK E+NSVG RAAYR Sbjct: 121 AGRYRQFHQFGVEVFGTADPAIDAEVIALGYSFYKELGLNGVKAEINSVGTPEVRAAYRS 180 Query: 181 KLLNFLRPMRDTLCSDCQRRMERNPLRVLDCKVDQDKFGGAPSILDSLDEECTTHFEQVK 240 LL FL PM+D+LCSDCQ RMERNPLRVLDCK DQ KFG APSIL+SLDEEC+THFE+V+ Sbjct: 181 ALLAFLEPMKDSLCSDCQSRMERNPLRVLDCKKDQGKFGDAPSILESLDEECSTHFEKVQ 240 Query: 241 AHLDVMGVEYSINPRLVRGLDYYTHTAFEYKAAXXXXXXXXXXXXRYNGLVEEIGGPDQP 300 +LD MG+EY INPRLVRGLDYYTHTAFE+KA R+NGLV +IGGPDQP Sbjct: 241 GYLDAMGIEYEINPRLVRGLDYYTHTAFEFKAQGIGAIDTVGGGGRFNGLVGQIGGPDQP 300 Query: 301 XXXXXXXXXXXXXXXENQGVELEAAKPLDVYFVALGEAADKEITKQLFTLRSLGYAAERD 360 E+QGV L A+KPLDVY VALGEAA++E+ K ++ LR G +AERD Sbjct: 301 GIGFGIGLERIQLILEHQGVNLSASKPLDVYLVALGEAAERELAKLIYELRRNGVSAERD 360 Query: 361 YLGRKMKAQMKSADRMNARYTAILGEDELNSGVIALKSMATGEQRTVKLEDL 412 YLGRKMKAQMKSADR+ ARYTAILG+DEL G IALKSM TGEQRTV+L+ L Sbjct: 361 YLGRKMKAQMKSADRLQARYTAILGDDELARGEIALKSMETGEQRTVRLDSL 412 >B1DIY7.1 B1DIY7_9BACL Histidyl-tRNA synthetase EC=6.1.1.21 Length = 416 Score = 592 bits (1525), Expect = e-167, Method: Compositional matrix adjust. Identities = 285/412 (69%), Positives = 325/412 (78%) Query: 6 FEKPTGTQDVLPGAVEKWLVVESKARDLCRRFNYREIRTPMFEHTGLFERGVGETTDIVE 65 F+K GTQD+LPG VE+W E KARD+CRRFN+REIRTP+FE T LF+RGVGETTDIVE Sbjct: 3 FQKSPGTQDILPGVVERWQYAEQKARDICRRFNFREIRTPIFEATELFQRGVGETTDIVE 62 Query: 66 GEMYTFKDKGDRDLALRPEGTAGVVRAYVQNKLYGEPDVSKLYYIGPMFRYERPQAGRYR 125 EMYTF D+GDR + LRPEGTAGVVR+YV+NKLYGEPDVSKLYYIGPMFRYER QAGRYR Sbjct: 63 KEMYTFTDRGDRSITLRPEGTAGVVRSYVENKLYGEPDVSKLYYIGPMFRYERQQAGRYR 122 Query: 126 QFHQFGIEAFGAVDPAIDAEVVSMGYQFYKDLGLKDVKVELNSVGNAPSRAAYREKLLNF 185 QFHQFGIEA G+V+PAIDAEV+++GY F+ ++GLK V+VE+NSVG RAA+REKLL F Sbjct: 123 QFHQFGIEALGSVEPAIDAEVIALGYTFFTEVGLKGVRVEINSVGTPAVRAAFREKLLAF 182 Query: 186 LRPMRDTLCSDCQRRMERNPLRVLDCKVDQDKFGGAPSILDSLDEECTTHFEQVKAHLDV 245 L PMR+ LC DCQ RMERNPLRVLDCK DQ +F APSILDSLDEECTTHFE+VK L Sbjct: 183 LMPMREQLCKDCQSRMERNPLRVLDCKTDQARFEAAPSILDSLDEECTTHFEKVKTCLSD 242 Query: 246 MGVEYSINPRLVRGLDYYTHTAFEYKAAXXXXXXXXXXXXRYNGLVEEIGGPDQPXXXXX 305 MG+ ++INPRLVRGLDYYTHTAFEYKA RYNGLV EIGGPDQP Sbjct: 243 MGIPFTINPRLVRGLDYYTHTAFEYKAEGIGAIDTIGGGGRYNGLVAEIGGPDQPGVGLG 302 Query: 306 XXXXXXXXXXENQGVELEAAKPLDVYFVALGEAADKEITKQLFTLRSLGYAAERDYLGRK 365 E+Q EL+ A +DVY VALGEAAD+E+T+ ++ LR+ G AERDYLGRK Sbjct: 303 LGLERTIMLLEHQQAELDNAHQVDVYVVALGEAADREVTRLVYELRTSGIRAERDYLGRK 362 Query: 366 MKAQMKSADRMNARYTAILGEDELNSGVIALKSMATGEQRTVKLEDLAASLN 417 MKAQMKSADR+ ARYTAILG+DEL G IALK MATGEQR V L LA+ L Sbjct: 363 MKAQMKSADRLQARYTAILGDDELERGEIALKEMATGEQRVVALASLASELK 414 >A7GT85.1 SYH_BACCN Histidyl-tRNA synthetase EC=6.1.1.21 Length = 423 Score = 464 bits (1194), Expect = e-129, Method: Compositional matrix adjust. Identities = 229/413 (55%), Positives = 291/413 (70%), Gaps = 5/413 (1%) Query: 9 PTGTQDVLPGAVEKWLVVESKARDLCRRFNYREIRTPMFEHTGLFERGVGETTDIVEGEM 68 P GTQD+LPG+VE W +E +AR++CRR+NY+EIRTP+FEHT LF RGVG+TTDIV+ EM Sbjct: 6 PRGTQDILPGSVELWQYIEGQAREICRRYNYKEIRTPIFEHTELFLRGVGDTTDIVQKEM 65 Query: 69 YTFKDKGDRDLALRPEGTAGVVRAYVQNKLYGEP-DVSKLYYIGPMFRYERPQAGRYRQF 127 YTF+D+GDR L LRPEGTA VVR+YV+NK++G+ +KLYYIG MFRYERPQAGRYRQF Sbjct: 66 YTFQDRGDRSLTLRPEGTAPVVRSYVENKMFGDATQPTKLYYIGQMFRYERPQAGRYRQF 125 Query: 128 HQFGIEAFGAVDPAIDAEVVSMGYQFYKDLGLKDVKVELNSVGNAPSRAAYREKLLNFLR 187 QFGIEA G+ DPAIDAEV+++ +FY+ +GLK++KV LNS+G+ SR A+RE L+ + Sbjct: 126 VQFGIEAIGSNDPAIDAEVIALAVEFYRGMGLKNIKVVLNSLGDPASRQAHREALIAHFK 185 Query: 188 PMRDTLCSDCQRRMERNPLRVLDCKVDQDK--FGGAPSILDSLDEECTTHFEQVKAHLDV 245 P CSDCQ R+E+NPLR+LDCK D+D APSI D L+EE T ++E+V+ L + Sbjct: 186 PRIGEFCSDCQSRLEKNPLRILDCKRDRDHELMNTAPSITDYLNEESTAYYEKVQELLTM 245 Query: 246 MGVEYSINPRLVRGLDYYTHTAFEY--KAAXXXXXXXXXXXXRYNGLVEEIGGPDQPXXX 303 MGV + +P LVRGLDYY HT FE +A RYNGLV+EIGGP+ P Sbjct: 246 MGVPFEKDPNLVRGLDYYQHTVFEIMSEAEGFGAITTLSGGGRYNGLVQEIGGPEMPGIG 305 Query: 304 XXXXXXXXXXXXENQGVELEAAKPLDVYFVALGEAADKEITKQLFTLRSLGYAAERDYLG 363 + + +EL +D Y VALG+ A K F LR G + E+DYL Sbjct: 306 FAMSIERLIMALKAENIELPIENTIDCYVVALGDKAKDHAAKVAFDLRKSGLSVEKDYLN 365 Query: 364 RKMKAQMKSADRMNARYTAILGEDELNSGVIALKSMATGEQRTVKLEDLAASL 416 RKMKAQ KSADR+NA+Y A+LGEDEL+ GVI LK MATGEQ V L+ A+ + Sbjct: 366 RKMKAQFKSADRLNAKYVAVLGEDELDKGVINLKDMATGEQEEVALDVFASYI 418 >C3BQD4.1 C3BQD4_9BACI Histidyl-tRNA synthetase 2 Length = 423 Score = 459 bits (1180), Expect = e-127, Method: Compositional matrix adjust. Identities = 227/411 (55%), Positives = 289/411 (70%), Gaps = 5/411 (1%) Query: 9 PTGTQDVLPGAVEKWLVVESKARDLCRRFNYREIRTPMFEHTGLFERGVGETTDIVEGEM 68 P GTQD+LPG VE W +E +AR++CRR+NY+EIRTP+FEHT LF RGVG+TTDIV+ EM Sbjct: 6 PRGTQDILPGTVELWQYIEGQAREICRRYNYKEIRTPIFEHTELFLRGVGDTTDIVQKEM 65 Query: 69 YTFKDKGDRDLALRPEGTAGVVRAYVQNKLYGEP-DVSKLYYIGPMFRYERPQAGRYRQF 127 Y+F+D+G+R L LRPEGTA VVR+YV+NK+YG+ +KLYYIG MFRYERPQAGRYRQF Sbjct: 66 YSFQDRGERSLTLRPEGTAPVVRSYVENKMYGDATQPTKLYYIGQMFRYERPQAGRYRQF 125 Query: 128 HQFGIEAFGAVDPAIDAEVVSMGYQFYKDLGLKDVKVELNSVGNAPSRAAYREKLLNFLR 187 QFGIEA G+ DPAIDAEV+++ +FY+ +GLK++KV LNS+G+A SR A+RE L+ Sbjct: 126 VQFGIEAIGSNDPAIDAEVIALAVEFYRGMGLKNIKVVLNSLGDAASRQAHREALIAHFE 185 Query: 188 PMRDTLCSDCQRRMERNPLRVLDCKVDQDK--FGGAPSILDSLDEECTTHFEQVKAHLDV 245 P CSDCQ R+E+NPLR+LDCK D+D APSI + L+EE TT++E+V+ L + Sbjct: 186 PRIGEFCSDCQSRLEKNPLRILDCKKDRDHELMSTAPSITEYLNEESTTYYEKVQELLTM 245 Query: 246 MGVEYSINPRLVRGLDYYTHTAFEY--KAAXXXXXXXXXXXXRYNGLVEEIGGPDQPXXX 303 MGV + +P LVRGLDYY HT FE +A RYNGLV+EIGGP+ P Sbjct: 246 MGVPFEKDPNLVRGLDYYQHTVFEIMSEADGFGAITTLSGGGRYNGLVQEIGGPEMPGIG 305 Query: 304 XXXXXXXXXXXXENQGVELEAAKPLDVYFVALGEAADKEITKQLFTLRSLGYAAERDYLG 363 + + +EL +D Y VALG+ A K F LR G + E+DYL Sbjct: 306 FAMSIERLIMALKAENIELPIEHNIDCYVVALGDKAKDHAAKIAFDLRKAGLSVEKDYLD 365 Query: 364 RKMKAQMKSADRMNARYTAILGEDELNSGVIALKSMATGEQRTVKLEDLAA 414 RKMKAQ KSADR+NA+Y A+LGEDEL+ G+I LK MATG Q V L+ A+ Sbjct: 366 RKMKAQFKSADRLNAKYVAVLGEDELDKGIINLKDMATGGQEEVALDVFAS 416 >C3B8E2.1 C3B8E2_BACMY Histidyl-tRNA synthetase 2 Length = 423 Score = 457 bits (1176), Expect = e-126, Method: Compositional matrix adjust. Identities = 225/411 (54%), Positives = 289/411 (70%), Gaps = 5/411 (1%) Query: 9 PTGTQDVLPGAVEKWLVVESKARDLCRRFNYREIRTPMFEHTGLFERGVGETTDIVEGEM 68 P GTQD+LPG +E W +E +AR++CRR+NY+EIRTP+FEHT LF RGVG+TTDIV+ EM Sbjct: 6 PRGTQDILPGTIELWQYIEGQAREICRRYNYKEIRTPIFEHTELFLRGVGDTTDIVQKEM 65 Query: 69 YTFKDKGDRDLALRPEGTAGVVRAYVQNKLYGEP-DVSKLYYIGPMFRYERPQAGRYRQF 127 Y+F+D+G+R L LRPEGTA VVR+YV+NK+YG+ +KLYYIG MFRYERPQAGRYRQF Sbjct: 66 YSFQDRGERSLTLRPEGTAPVVRSYVENKMYGDATQPTKLYYIGQMFRYERPQAGRYRQF 125 Query: 128 HQFGIEAFGAVDPAIDAEVVSMGYQFYKDLGLKDVKVELNSVGNAPSRAAYREKLLNFLR 187 QFGIEA G+ DPAIDAEV+++ +FY+ +GLK++KV LNS+G+A SR A+RE L+ Sbjct: 126 VQFGIEAIGSNDPAIDAEVIALAVEFYRGMGLKNIKVVLNSLGDAASRQAHREALIAHFE 185 Query: 188 PMRDTLCSDCQRRMERNPLRVLDCKVDQDK--FGGAPSILDSLDEECTTHFEQVKAHLDV 245 P CSDCQ R+E+NPLR+LDCK D++ APSI + L+EE TT++E+V+ L + Sbjct: 186 PRIGEFCSDCQSRLEKNPLRILDCKKDRNHELMSTAPSITEYLNEESTTYYEKVQELLTM 245 Query: 246 MGVEYSINPRLVRGLDYYTHTAFEY--KAAXXXXXXXXXXXXRYNGLVEEIGGPDQPXXX 303 MGV + +P LVRGLDYY HT FE +A RYNGLV+EIGGP+ P Sbjct: 246 MGVPFEKDPNLVRGLDYYQHTVFEIMSEADGFGAITTLSGGGRYNGLVQEIGGPEMPGIG 305 Query: 304 XXXXXXXXXXXXENQGVELEAAKPLDVYFVALGEAADKEITKQLFTLRSLGYAAERDYLG 363 + + +EL +D Y VALG+ A K F LR G + E+DYL Sbjct: 306 FAMSIERLIMALKAENIELPIEHNIDCYVVALGDKAKDHAAKIAFDLRKAGLSVEKDYLD 365 Query: 364 RKMKAQMKSADRMNARYTAILGEDELNSGVIALKSMATGEQRTVKLEDLAA 414 RKMKAQ KSADR+NA+Y A+LGEDEL+ G+I LK MATG Q V L+ A+ Sbjct: 366 RKMKAQFKSADRLNAKYVAVLGEDELDKGIINLKDMATGGQEEVALDVFAS 416 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.137 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,295,639,173 Number of extensions: 91619063 Number of successful extensions: 186911 Number of sequences better than 1.0e-05: 1900 Number of HSP's gapped: 181852 Number of HSP's successfully gapped: 2013 Length of query: 417 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 279 Effective length of database: 1,760,596,133 Effective search space: 491206321107 Effective search space used: 491206321107 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 132 (55.5 bits)