BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0265.0006.p (363 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q6HE83.1 Q6HE83_BACHK Xanthine/uracil permease family protein 253 3e-65 C0Z7P8.1 C0Z7P8_BREBN Purine permease 252 4e-65 Q819A3.1 Q819A3_BACCR Guanine-hypoxanthine permease 251 9e-65 C3EQ71.1 C3EQ71_BACTK Xanthine/uracil permease 251 9e-65 B7H975.1 B7H975_BACC4 Xanthine/uracil permease family protein 250 1e-64 >Q6HE83.1 Q6HE83_BACHK Xanthine/uracil permease family protein Length = 429 Score = 253 bits (645), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 132/281 (46%), Positives = 188/281 (66%), Gaps = 3/281 (1%) Query: 19 KRELSAGILSYFASVYIVMVNAAILHDAGMPLRAGMVATLLTAVAGCLLMAFGGKTPIVV 78 K+E+ AG+ S+F VYI++VNA+IL DAG+PL AG++AT+ ++ GCLLMAF P ++ Sbjct: 19 KQEVLAGVTSFFTIVYIMIVNASILSDAGIPLEAGILATVFSSFVGCLLMAFWANAPAIL 78 Query: 79 VPGMGINAFFTYTLVHSMKLDWREALAVVAVTGVLFAIVAFTSLYRILSDAIPHNLQHAI 138 VPGMG+NAFFTYT VH++ L W+EALA V ++G++FAI AFT + R+LS +IP +L+ AI Sbjct: 79 VPGMGVNAFFTYTAVHTLGLTWQEALAAVFISGIIFAIAAFTPIARVLSVSIPKSLKEAI 138 Query: 139 TVGIGLFLTFIGLQKSGIVIAHRTTFVAIGHFSDPAVITSCVTLILALVLFIRGTRGGLL 198 TVGIGLFL FIGLQKSG+V+++ T VA+G S+P V+ + +TLI+ALVLFIR RG L Sbjct: 139 TVGIGLFLAFIGLQKSGLVVSNPNTAVAMGKLSNPVVLATVLTLIVALVLFIRNVRGNFL 198 Query: 199 ISMLAGTGMAYLLGAAHVPENTDSGHMFAGYSGVFAGMDWGRGLSXXXXXXXXXXXXXXX 258 ++ GTG+A+L G + +S FA Y VF M +G+ S Sbjct: 199 WTIAIGTGIAWLFGLVDTSQVGNSSFSFANYGDVFGAMSFGKLSSLPFWIATFSLSMVLI 258 Query: 259 XENIGLISSQTLMAGRPERFKSSLRALSIANIAAGLFGSSP 299 EN+GL+ + +F + +A +I+ + GLFG+SP Sbjct: 259 FENMGLLHG---LLEDDRKFPRAYQANAISAMTCGLFGTSP 296 >C0Z7P8.1 C0Z7P8_BREBN Purine permease Length = 430 Score = 252 bits (644), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 136/285 (47%), Positives = 188/285 (65%), Gaps = 4/285 (1%) Query: 16 DNWKRELSAGILSYFASVYIVMVNAAILHDAGMPLRAGMVATLLTAVAGCLLMAFGGKTP 75 ++REL AG + + VYIV VNA+IL+DAG+P+ AG++AT+LTA G LLMAF P Sbjct: 16 TTFQRELIAGFIGFVTIVYIVAVNASILNDAGIPMEAGILATVLTAFIGSLLMAFWANAP 75 Query: 76 IVVVPGMGINAFFTYTLVHSMKLDWREALAVVAVTGVLFAIVAFTSLYRILSDAIPHNLQ 135 I++VPGMGINA FT+TL SM L W++ALA V V+G++F ++AFT ILS+AIP +L+ Sbjct: 76 IILVPGMGINALFTFTLCQSMGLTWQQALAAVFVSGLIFTVIAFTKAATILSNAIPASLK 135 Query: 136 HAITVGIGLFLTFIGLQKSGIVIAHRTTFVAIGHFSDPAVITSCVTLILALVLFIRGTRG 195 AITVGIGLFLTFIGLQK G+++ + +TFVA+G S P VI + +TLI+ L+LF+R G Sbjct: 136 EAITVGIGLFLTFIGLQKGGLIVMNPSTFVALGDLSSPHVIVTLITLIVTLILFVRNVPG 195 Query: 196 GLLISMLAGTGMAYLLGAAHVPENTDSGHM-FAGYSGVFAGMDWGRGLSXXXXXXXXXXX 254 LI + GTG+ +L G + E G FA Y VFAG+ + + Sbjct: 196 NFLIGIAVGTGLGFLFG---IVEPGGGGTFSFADYGSVFAGLSFSAIWALPFWIATFSLA 252 Query: 255 XXXXXENIGLISSQTLMAGRPERFKSSLRALSIANIAAGLFGSSP 299 ENIGLI T M G+P++F+ SL+A +++ +G+ GSSP Sbjct: 253 MVIVFENIGLIHGHTSMLGQPQKFRRSLQANALSAAISGILGSSP 297 >Q819A3.1 Q819A3_BACCR Guanine-hypoxanthine permease Length = 429 Score = 251 bits (640), Expect = 9e-65, Method: Compositional matrix adjust. Identities = 131/281 (46%), Positives = 187/281 (66%), Gaps = 3/281 (1%) Query: 19 KRELSAGILSYFASVYIVMVNAAILHDAGMPLRAGMVATLLTAVAGCLLMAFGGKTPIVV 78 K+E+ AG+ S+F VYI++VNA+IL DAG+PL AG++AT+ ++ GCLLMAF P ++ Sbjct: 19 KQEVLAGVTSFFTIVYIMIVNASILSDAGIPLEAGILATVFSSFVGCLLMAFWANAPAIL 78 Query: 79 VPGMGINAFFTYTLVHSMKLDWREALAVVAVTGVLFAIVAFTSLYRILSDAIPHNLQHAI 138 VPGMG+NAFFTYT VH++ L W+EALA V ++G++FAI AFT + R+LS +IP +L+ AI Sbjct: 79 VPGMGVNAFFTYTAVHTLGLTWQEALAAVFISGIIFAIAAFTPIARVLSVSIPKSLKEAI 138 Query: 139 TVGIGLFLTFIGLQKSGIVIAHRTTFVAIGHFSDPAVITSCVTLILALVLFIRGTRGGLL 198 TVGIGLFL FIGLQK G+V+++ T VA+G S+P V+ + +TLI+ALVLFIR RG L Sbjct: 139 TVGIGLFLAFIGLQKGGLVVSNPNTAVAMGKLSNPVVLATVLTLIIALVLFIRNVRGNFL 198 Query: 199 ISMLAGTGMAYLLGAAHVPENTDSGHMFAGYSGVFAGMDWGRGLSXXXXXXXXXXXXXXX 258 ++ GTG+A+L G + +S FA Y VF M +G+ S Sbjct: 199 WTIAIGTGIAWLFGLVDTSQIGNSSFSFANYGDVFGAMSFGKLSSLPFWIATFSLSMVLI 258 Query: 259 XENIGLISSQTLMAGRPERFKSSLRALSIANIAAGLFGSSP 299 EN+GL+ + +F + +A +I+ + GLFG+SP Sbjct: 259 FENMGLLHG---LLEDDRKFPRAYQANAISAMTCGLFGTSP 296 >C3EQ71.1 C3EQ71_BACTK Xanthine/uracil permease Length = 429 Score = 251 bits (640), Expect = 9e-65, Method: Compositional matrix adjust. Identities = 132/281 (46%), Positives = 186/281 (66%), Gaps = 3/281 (1%) Query: 19 KRELSAGILSYFASVYIVMVNAAILHDAGMPLRAGMVATLLTAVAGCLLMAFGGKTPIVV 78 K+E+ AG+ S+F VYI++VNA+IL DAG+PL AG++AT+ ++ GCLLMAF P ++ Sbjct: 19 KQEVLAGVTSFFTIVYIMIVNASILSDAGIPLEAGILATVFSSFVGCLLMAFWANAPAIL 78 Query: 79 VPGMGINAFFTYTLVHSMKLDWREALAVVAVTGVLFAIVAFTSLYRILSDAIPHNLQHAI 138 VPGMG+NAFFTYT VH++ L W+EALA V ++G++FAI AFT + R+LS +IP +L+ AI Sbjct: 79 VPGMGVNAFFTYTAVHTLGLTWQEALAAVFISGIIFAIAAFTPIARVLSVSIPKSLKEAI 138 Query: 139 TVGIGLFLTFIGLQKSGIVIAHRTTFVAIGHFSDPAVITSCVTLILALVLFIRGTRGGLL 198 TVGIGLFL FIGLQK G+V+++ T VA+G S+P V+ + +TLI+ALVLFIR RG L Sbjct: 139 TVGIGLFLAFIGLQKGGLVVSNPNTAVAMGKLSNPVVLATLLTLIIALVLFIRNVRGNFL 198 Query: 199 ISMLAGTGMAYLLGAAHVPENTDSGHMFAGYSGVFAGMDWGRGLSXXXXXXXXXXXXXXX 258 ++ GTG+A+L G + S FA Y VF M +G+ S Sbjct: 199 WTIAIGTGIAWLFGLVDTSQVGSSSFSFANYGDVFGAMSFGKLSSLPFWIATFSLSMVLI 258 Query: 259 XENIGLISSQTLMAGRPERFKSSLRALSIANIAAGLFGSSP 299 EN+GL+ + +F + +A +I+ I GLFG+SP Sbjct: 259 FENMGLLHG---LLEDDRKFPRAYQANAISAITCGLFGTSP 296 >B7H975.1 B7H975_BACC4 Xanthine/uracil permease family protein Length = 429 Score = 250 bits (639), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 131/281 (46%), Positives = 187/281 (66%), Gaps = 3/281 (1%) Query: 19 KRELSAGILSYFASVYIVMVNAAILHDAGMPLRAGMVATLLTAVAGCLLMAFGGKTPIVV 78 K+E+ AG+ S+F VYI++VNA+IL DAG+PL AG++AT+ ++ GCLLMAF P ++ Sbjct: 19 KQEVLAGVTSFFTIVYIMIVNASILSDAGIPLEAGILATVFSSFVGCLLMAFWANAPAIL 78 Query: 79 VPGMGINAFFTYTLVHSMKLDWREALAVVAVTGVLFAIVAFTSLYRILSDAIPHNLQHAI 138 VPGMG+NAFFTYT VH++ L W+EALA V ++G++FAI AFT + R+LS +IP +L+ AI Sbjct: 79 VPGMGVNAFFTYTAVHTLGLTWQEALAAVFISGIIFAIAAFTPIARVLSISIPKSLKEAI 138 Query: 139 TVGIGLFLTFIGLQKSGIVIAHRTTFVAIGHFSDPAVITSCVTLILALVLFIRGTRGGLL 198 TVGIGLFL FIGLQK G+V+++ T VA+G S+P V+ + +TLI+ALVLFIR RG L Sbjct: 139 TVGIGLFLAFIGLQKGGLVVSNPNTAVAMGKLSNPVVLATLLTLIIALVLFIRNVRGNFL 198 Query: 199 ISMLAGTGMAYLLGAAHVPENTDSGHMFAGYSGVFAGMDWGRGLSXXXXXXXXXXXXXXX 258 ++ GTG+A+L G + +S FA Y VF M +G+ S Sbjct: 199 WTIAIGTGIAWLFGLVDTSQVGNSSFSFANYGDVFGAMSFGKLSSLPFWIATFSLSMVLI 258 Query: 259 XENIGLISSQTLMAGRPERFKSSLRALSIANIAAGLFGSSP 299 EN+GL+ + +F + +A +I+ + GLFG+SP Sbjct: 259 FENMGLLHG---LLEDDRKFPRAYQANAISAMTCGLFGTSP 296 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.325 0.139 0.419 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,914,740,477 Number of extensions: 73276539 Number of successful extensions: 265800 Number of sequences better than 1.0e-05: 1954 Number of HSP's gapped: 264395 Number of HSP's successfully gapped: 1954 Length of query: 363 Length of database: 3,060,696,203 Length adjustment: 137 Effective length of query: 226 Effective length of database: 1,770,017,148 Effective search space: 400023875448 Effective search space used: 400023875448 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 132 (55.5 bits)