BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0264.0055.p (423 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KG79.1 B3KG79_9BACI Adenosylhomocysteinase EC=3.3.1.1 702 0.0 B1DBW8.1 B1DBW8_9BACL Adenosylhomocysteinase EC=3.3.1.1 682 0.0 C0ZGB5.1 C0ZGB5_BREBN Probable adenosylhomocysteinase EC=3.3.1.1 670 0.0 C1TJJ4.1 C1TJJ4_9FIRM Adenosylhomocysteinase EC=3.3.1.1 583 e-164 A4J677.1 A4J677_DESRM Adenosylhomocysteinase EC=3.3.1.1 577 e-163 >B3KG79.1 B3KG79_9BACI Adenosylhomocysteinase EC=3.3.1.1 Length = 422 Score = 702 bits (1811), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/419 (82%), Positives = 378/419 (90%) Query: 1 MSSLSKENSIVADMSLAPEGHLKIDWVRQHMPVLNRIREQFEAEQPFKGLKVSITLHLEA 60 MSS S + S +AD+ LAPEGHLKIDWV+ HMPVLNR+REQFE EQPFKGLKV+I+LHLEA Sbjct: 1 MSSSSIQTSNIADLKLAPEGHLKIDWVQAHMPVLNRVREQFEKEQPFKGLKVAISLHLEA 60 Query: 61 KTAYLAKVVQAGGAEVTITGSNPLSTQDDVCAALVEDGITVFAKYNPSPEEFKALNIKAL 120 KTAYLAKVVQAGGAEVTITGSNPLSTQDDVCAALVEDGITVFAKYNP PEE+K I L Sbjct: 61 KTAYLAKVVQAGGAEVTITGSNPLSTQDDVCAALVEDGITVFAKYNPDPEEYKQHLISTL 120 Query: 121 ESKPDLIIDDGGDFATLLHSERPDLMENIRGGAEETTTGIIRLKALQKQGILKFPMVAVN 180 E++PDLIIDDGGD T+LHSER DL+E +RGGAEETTTGI+RLK+L+K+G LKFPMVAVN Sbjct: 121 ETRPDLIIDDGGDLVTILHSERTDLLEGVRGGAEETTTGILRLKSLEKEGALKFPMVAVN 180 Query: 181 DAYCKYLFDNRYGTGQSAWDGIVRTTNLIVAGKTVVVVGYGWCGKGVAMRAKGLGANVIV 240 DAYCKYLFDNRYGTGQS WDGI RTTNL+VAGKTVVVVGYGWCGKGVAMRAKGLGANVIV Sbjct: 181 DAYCKYLFDNRYGTGQSVWDGINRTTNLVVAGKTVVVVGYGWCGKGVAMRAKGLGANVIV 240 Query: 241 TEVDAIKAVEAHMDGFHVMPMLEAAKRGDFFVTVTGNRYVIRGEHYDVMKDGAIMCNAGH 300 TE+D IKAVEA+MDGFHVMPM EAAKRGDFFVTVTGNR VI GE +DVMKDGAI+ NAGH Sbjct: 241 TEIDPIKAVEAYMDGFHVMPMREAAKRGDFFVTVTGNRDVISGEDFDVMKDGAILSNAGH 300 Query: 301 FDVEVNKPELSDRSVSQRTVRKNIEEYQLKDGRKLYLLAEGRLVNLGAADGHPAEIMDTT 360 FDVEVNKP+LS+RS S RTVR+NIEEY LKDGRK+YLLAEGRLVNL A DGHPAEIMD T Sbjct: 301 FDVEVNKPDLSERSQSVRTVRRNIEEYHLKDGRKIYLLAEGRLVNLAAGDGHPAEIMDMT 360 Query: 361 FALQALSLKYVNDNYKTIGVKVENVPYDLDEQVARFKLESLGISIDSLTPAQVEYLDSW 419 FALQALSLK+VND Y++IG +V NVPY+LD+QVA +KLESLGI IDSL+ Q YLDSW Sbjct: 361 FALQALSLKHVNDQYQSIGNRVVNVPYELDQQVALYKLESLGIHIDSLSAEQKSYLDSW 419 >B1DBW8.1 B1DBW8_9BACL Adenosylhomocysteinase EC=3.3.1.1 Length = 420 Score = 682 bits (1759), Expect = 0.0, Method: Compositional matrix adjust. Identities = 334/419 (79%), Positives = 373/419 (89%), Gaps = 2/419 (0%) Query: 1 MSSLSKENSIVADMSLAPEGHLKIDWVRQHMPVLNRIREQFEAEQPFKGLKVSITLHLEA 60 MS+L K S++ D++LAPEGHLKIDW HMPVLNRIREQFE + PFKGLKV+I+LHLEA Sbjct: 1 MSTLEK--SMIRDIALAPEGHLKIDWASAHMPVLNRIREQFEQDLPFKGLKVTISLHLEA 58 Query: 61 KTAYLAKVVQAGGAEVTITGSNPLSTQDDVCAALVEDGITVFAKYNPSPEEFKALNIKAL 120 KTAYLAKVV+AGGA+VTITGSNPLSTQDD+CAALVEDGITVFAKYNP PEE+K L IK+L Sbjct: 59 KTAYLAKVVKAGGADVTITGSNPLSTQDDICAALVEDGITVFAKYNPEPEEYKELLIKSL 118 Query: 121 ESKPDLIIDDGGDFATLLHSERPDLMENIRGGAEETTTGIIRLKALQKQGILKFPMVAVN 180 ESKPDLIIDDGGD T+LH+ERPDL EN+RGGAEETTTGIIRLKA++K+G L FPMVAVN Sbjct: 119 ESKPDLIIDDGGDLVTILHTERPDLRENLRGGAEETTTGIIRLKAMEKEGTLSFPMVAVN 178 Query: 181 DAYCKYLFDNRYGTGQSAWDGIVRTTNLIVAGKTVVVVGYGWCGKGVAMRAKGLGANVIV 240 DAYCKYLFDNRYGTGQS +DGI RTTNL+VAGKTVVVVGYGWCGKGVAMRAKGLGANV+V Sbjct: 179 DAYCKYLFDNRYGTGQSVFDGINRTTNLVVAGKTVVVVGYGWCGKGVAMRAKGLGANVVV 238 Query: 241 TEVDAIKAVEAHMDGFHVMPMLEAAKRGDFFVTVTGNRYVIRGEHYDVMKDGAIMCNAGH 300 TEVDAIKAVEA+MDGF V+PM EAAK G+ F+TVTGN+ IR EHY+VMK+GAI+ NAGH Sbjct: 239 TEVDAIKAVEAYMDGFTVLPMSEAAKAGELFITVTGNKDCIRAEHYEVMKNGAILSNAGH 298 Query: 301 FDVEVNKPELSDRSVSQRTVRKNIEEYQLKDGRKLYLLAEGRLVNLGAADGHPAEIMDTT 360 FDVE NKPEL+ S RTVR+NIEEY+LKDGR +Y+LAEGRLVNL A DGHPAEIMDTT Sbjct: 299 FDVEFNKPELAAMSTDIRTVRRNIEEYKLKDGRSIYVLAEGRLVNLAAGDGHPAEIMDTT 358 Query: 361 FALQALSLKYVNDNYKTIGVKVENVPYDLDEQVARFKLESLGISIDSLTPAQVEYLDSW 419 FALQAL L+YVN+ Y IG KV NVPY+LDEQVARFKL+SL ISID LTP QV YLDSW Sbjct: 359 FALQALGLRYVNEQYANIGNKVVNVPYELDEQVARFKLDSLNISIDKLTPEQVTYLDSW 417 >C0ZGB5.1 C0ZGB5_BREBN Probable adenosylhomocysteinase EC=3.3.1.1 Length = 419 Score = 670 bits (1728), Expect = 0.0, Method: Compositional matrix adjust. Identities = 321/419 (76%), Positives = 364/419 (86%), Gaps = 2/419 (0%) Query: 1 MSSLSKENSIVADMSLAPEGHLKIDWVRQHMPVLNRIREQFEAEQPFKGLKVSITLHLEA 60 M+++S+ SIV DM+LA GHLKIDWV++HMPVLNRIRE+FE EQPF GLKV+I+LHLEA Sbjct: 1 MNTVSE--SIVKDMALAHNGHLKIDWVKEHMPVLNRIRERFEKEQPFAGLKVAISLHLEA 58 Query: 61 KTAYLAKVVQAGGAEVTITGSNPLSTQDDVCAALVEDGITVFAKYNPSPEEFKALNIKAL 120 KTAYLAKVVQAGGAEVTITGSNPLSTQDD+CAALVEDGI VFAKYNP P E+K IK L Sbjct: 59 KTAYLAKVVQAGGAEVTITGSNPLSTQDDICAALVEDGIRVFAKYNPDPAEYKEHLIKTL 118 Query: 121 ESKPDLIIDDGGDFATLLHSERPDLMENIRGGAEETTTGIIRLKALQKQGILKFPMVAVN 180 E++PDLIIDDGGD T+LHSER DL+ +RGGAEETTTGI+RLKAL+K+G L+FPMVAVN Sbjct: 119 ETRPDLIIDDGGDLITILHSERRDLLSQVRGGAEETTTGILRLKALEKEGKLEFPMVAVN 178 Query: 181 DAYCKYLFDNRYGTGQSAWDGIVRTTNLIVAGKTVVVVGYGWCGKGVAMRAKGLGANVIV 240 DA+CKYLFDNRYGTGQS WDGI RTTNL+VAGKTVVV GYGWCGKGVAMRAKGLGA VIV Sbjct: 179 DAFCKYLFDNRYGTGQSVWDGINRTTNLVVAGKTVVVAGYGWCGKGVAMRAKGLGAKVIV 238 Query: 241 TEVDAIKAVEAHMDGFHVMPMLEAAKRGDFFVTVTGNRYVIRGEHYDVMKDGAIMCNAGH 300 TE+D IKAVEA+MDGF VMPMLEAAK GD+FVTVTGNR +I EH+ VMKDGAI+ NAGH Sbjct: 239 TEIDPIKAVEAYMDGFEVMPMLEAAKHGDYFVTVTGNRDIISKEHFAVMKDGAILSNAGH 298 Query: 301 FDVEVNKPELSDRSVSQRTVRKNIEEYQLKDGRKLYLLAEGRLVNLGAADGHPAEIMDTT 360 FDVEVNK +L+ S S R VRK+IEE+ L DGRK+YLLAEGRLVNL A DGHPAEIMD T Sbjct: 299 FDVEVNKVDLNAMSTSSRIVRKDIEEFVLTDGRKVYLLAEGRLVNLAAGDGHPAEIMDMT 358 Query: 361 FALQALSLKYVNDNYKTIGVKVENVPYDLDEQVARFKLESLGISIDSLTPAQVEYLDSW 419 FALQA+SL YVN+ YK IG KV NVP++LD+ VA++KLE+L I ID LT AQ YL+SW Sbjct: 359 FALQAVSLAYVNEQYKNIGKKVLNVPFELDQMVAQYKLEALNIGIDKLTDAQKSYLESW 417 >C1TJJ4.1 C1TJJ4_9FIRM Adenosylhomocysteinase EC=3.3.1.1 Length = 417 Score = 583 bits (1502), Expect = e-164, Method: Compositional matrix adjust. Identities = 275/410 (67%), Positives = 335/410 (81%) Query: 10 IVADMSLAPEGHLKIDWVRQHMPVLNRIREQFEAEQPFKGLKVSITLHLEAKTAYLAKVV 69 IV D+ LAP G LKIDWVR+HMPVLN IR +FE E PFKG++V+I++HLEAKTAYLA+V+ Sbjct: 5 IVRDIKLAPGGRLKIDWVREHMPVLNEIRAEFEKELPFKGIRVAISIHLEAKTAYLAEVL 64 Query: 70 QAGGAEVTITGSNPLSTQDDVCAALVEDGITVFAKYNPSPEEFKALNIKALESKPDLIID 129 +AGGA+V+I+GSNPLSTQDDV AAL E GI VF+ YN +PEE+K ++ L++KP +IID Sbjct: 65 KAGGADVSISGSNPLSTQDDVAAALAEAGINVFSWYNSTPEEYKEHLLQVLDTKPQIIID 124 Query: 130 DGGDFATLLHSERPDLMENIRGGAEETTTGIIRLKALQKQGILKFPMVAVNDAYCKYLFD 189 DGGD LLH+ER +L+ N+ GG EETTTG+IRL+AL+++G L FPMVAVNDAYCKYLFD Sbjct: 125 DGGDLVNLLHTERKNLVVNVLGGCEETTTGVIRLRALEREGGLLFPMVAVNDAYCKYLFD 184 Query: 190 NRYGTGQSAWDGIVRTTNLIVAGKTVVVVGYGWCGKGVAMRAKGLGANVIVTEVDAIKAV 249 NRYGTG+S W GI+RTTNLIVAGKTVVV+GYGWCGKGVAMRAKG+GA VIV E+D IKA+ Sbjct: 185 NRYGTGESVWSGIMRTTNLIVAGKTVVVIGYGWCGKGVAMRAKGMGAKVIVCEIDPIKAI 244 Query: 250 EAHMDGFHVMPMLEAAKRGDFFVTVTGNRYVIRGEHYDVMKDGAIMCNAGHFDVEVNKPE 309 EA MDGF VM EA+ GD F+TVTG + V+ EHY +MK+GAI+ NAGHFDVEVNKP+ Sbjct: 245 EAFMDGFQVMSAKEASVSGDIFITVTGCKDVLTKEHYQLMKNGAILSNAGHFDVEVNKPD 304 Query: 310 LSDRSVSQRTVRKNIEEYQLKDGRKLYLLAEGRLVNLGAADGHPAEIMDTTFALQALSLK 369 L +VS RTVRK+IEEY + DGRK+YLLAEGRLVNL A DGHPAEIMD +FALQALS + Sbjct: 305 LEKTAVSHRTVRKDIEEYAMTDGRKIYLLAEGRLVNLAAGDGHPAEIMDMSFALQALSAR 364 Query: 370 YVNDNYKTIGVKVENVPYDLDEQVARFKLESLGISIDSLTPAQVEYLDSW 419 Y+ N + KV +VP ++D +VA KL SL I+ID LT Q +YL+SW Sbjct: 365 YILKNAAALDKKVYDVPKEIDSRVAEIKLRSLDINIDKLTQEQEDYLNSW 414 >A4J677.1 A4J677_DESRM Adenosylhomocysteinase EC=3.3.1.1 Length = 418 Score = 577 bits (1488), Expect = e-163, Method: Compositional matrix adjust. Identities = 274/411 (66%), Positives = 334/411 (81%) Query: 10 IVADMSLAPEGHLKIDWVRQHMPVLNRIREQFEAEQPFKGLKVSITLHLEAKTAYLAKVV 69 IV D++LAP G LKIDWVRQHMPVLN IR QFE EQPFKG +V++ +HLEAKTAYLA+V+ Sbjct: 5 IVRDINLAPAGRLKIDWVRQHMPVLNEIRAQFEKEQPFKGYRVAVCIHLEAKTAYLAEVL 64 Query: 70 QAGGAEVTITGSNPLSTQDDVCAALVEDGITVFAKYNPSPEEFKALNIKALESKPDLIID 129 +AGGAEV+I GSNPLSTQDDV AAL G+ V++ YN + EE+K + ++ +PD++ID Sbjct: 65 RAGGAEVSIAGSNPLSTQDDVAAALAAAGLNVYSWYNATDEEYKEHLLHLIDDQPDIVID 124 Query: 130 DGGDFATLLHSERPDLMENIRGGAEETTTGIIRLKALQKQGILKFPMVAVNDAYCKYLFD 189 DGGD LLH+ER + + GG EETTTG++RL++L KQG LKFPM+AVNDAYCKYLFD Sbjct: 125 DGGDVVQLLHTERTEAASRVLGGCEETTTGVLRLRSLAKQGELKFPMIAVNDAYCKYLFD 184 Query: 190 NRYGTGQSAWDGIVRTTNLIVAGKTVVVVGYGWCGKGVAMRAKGLGANVIVTEVDAIKAV 249 NRYGTG+S W GI+RTTNLI AGKTVVV GYGWCGKG+AMRAKG+GA VIVTEVD +KA+ Sbjct: 185 NRYGTGESVWSGIMRTTNLITAGKTVVVAGYGWCGKGIAMRAKGMGAKVIVTEVDPVKAI 244 Query: 250 EAHMDGFHVMPMLEAAKRGDFFVTVTGNRYVIRGEHYDVMKDGAIMCNAGHFDVEVNKPE 309 EA+MDGFH M LEAAK GD F+TVTG + V G HY+ MKDGAI+CNAGHFDVEVNKP+ Sbjct: 245 EAYMDGFHPMNSLEAAKLGDIFITVTGCKDVFTGVHYERMKDGAILCNAGHFDVEVNKPD 304 Query: 310 LSDRSVSQRTVRKNIEEYQLKDGRKLYLLAEGRLVNLGAADGHPAEIMDTTFALQALSLK 369 L + S+R VRK+IEE+ +KDGRK+YLLAEGRLVNL A DGHPAEIMD +FALQALS + Sbjct: 305 LLALATSRRIVRKDIEEFTMKDGRKIYLLAEGRLVNLAAGDGHPAEIMDMSFALQALSAR 364 Query: 370 YVNDNYKTIGVKVENVPYDLDEQVARFKLESLGISIDSLTPAQVEYLDSWN 420 YV +N K + +V VP ++D++VA KL+SLG+ IDSLTP Q Y++ WN Sbjct: 365 YVLENAKKLSNEVYVVPKEIDDRVANLKLKSLGVDIDSLTPEQEAYINEWN 415 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.135 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,495,206,378 Number of extensions: 104717552 Number of successful extensions: 324339 Number of sequences better than 1.0e-05: 1133 Number of HSP's gapped: 322214 Number of HSP's successfully gapped: 1573 Length of query: 423 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 285 Effective length of database: 1,760,596,133 Effective search space: 501769897905 Effective search space used: 501769897905 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 133 (55.8 bits)