BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0264.0020.p (417 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KGB3.1 B3KGB3_9BACI Aminotransferase class I and II 717 0.0 A4XHK6.1 A4XHK6_CALS8 Aminotransferase EC=2.6.1.- 570 e-161 B9MPB1.1 B9MPB1_ANATD Aminotransferase class I and II 563 e-159 A6UX48.1 A6UX48_META3 Aminotransferase class I and II 541 e-152 A8TE48.1 A8TE48_METVO Aminotransferase class I and II 527 e-148 >B3KGB3.1 B3KGB3_9BACI Aminotransferase class I and II Length = 417 Score = 717 bits (1851), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/417 (84%), Positives = 379/417 (90%) Query: 1 MSIEQYQETFIQTNFADRIGGANYGKDTAIYKFEKIKRAKASAKQDFPNIELIDMGVGEP 60 MS+++YQET+IQ +FADRIGGANYGKDTAIYKFEKIKRAKA+AKQ+ P+ ELIDMGVGEP Sbjct: 1 MSMDKYQETYIQQSFADRIGGANYGKDTAIYKFEKIKRAKAAAKQEHPDTELIDMGVGEP 60 Query: 61 DEMADEGIXXXXXXXXXXXXNRGYSDNGIPEFKAAAAAYLKEVFRVDGIDPVTEVVHSIG 120 DEMAD GI NRGY+DNGIPEFK AA YL VF V+GID TEV+HSIG Sbjct: 61 DEMADAGIVAKLAEEAAKRENRGYADNGIPEFKEAAVRYLSNVFGVEGIDASTEVLHSIG 120 Query: 121 SKPALAMLPSCFINPGDITIMTVPGYPVLGTHTKYLGGQVFTVELKKENNFLPDLNSIPE 180 SKPALAMLPSCFINPGDITIMTVPGYPVLGTHTKYLGG+V+ VELKKEN FLPDL SIPE Sbjct: 121 SKPALAMLPSCFINPGDITIMTVPGYPVLGTHTKYLGGEVYNVELKKENAFLPDLGSIPE 180 Query: 181 DVARKAKLLYLNYPNNPTGASATPEFFSEVVAWAKKYDVVVIHDAPYAALTYDGMKPLSF 240 D+AR+AKLLYLNYPNNPTGASAT EFF+EVV WA+KY VVV+HDAPYAALTYDG+KPLSF Sbjct: 181 DIARRAKLLYLNYPNNPTGASATAEFFAEVVEWARKYGVVVVHDAPYAALTYDGLKPLSF 240 Query: 241 LSVPGAKDVGVELHSLSKSYNMTGWRIGFVAGNPLVVKAFSDVKDNNDSGQFIAIQKAAA 300 LSVPGAKDVGVELHSLSKSYNMTGWRIGF+AGNPLVVKAF DVKDNNDSGQFIAIQKAAA Sbjct: 241 LSVPGAKDVGVELHSLSKSYNMTGWRIGFIAGNPLVVKAFGDVKDNNDSGQFIAIQKAAA 300 Query: 301 YGLEHPEITEAIAAKYSRRHNMLVDALNSLGFSAEKPKGSFFLYVAAPKGIKGGRRFESG 360 YGL+HPEITE IA KYSRRHNMLVD LN LGF+AEKPKGSFFLYV APKG+KGGRRFESG Sbjct: 301 YGLDHPEITEKIAEKYSRRHNMLVDVLNGLGFTAEKPKGSFFLYVEAPKGVKGGRRFESG 360 Query: 361 EDFSQFLIREKLISTVPWDDAGPFVRFSVTFIAKGEEEEKRVISEIQRRLSDVEFEF 417 EDFSQ+LIREKLISTVPWDDAG FVRFSVTFIA GEEEEKRVISEI+RRLSDVEFEF Sbjct: 361 EDFSQYLIREKLISTVPWDDAGHFVRFSVTFIADGEEEEKRVISEIRRRLSDVEFEF 417 >A4XHK6.1 A4XHK6_CALS8 Aminotransferase EC=2.6.1.- Length = 411 Score = 570 bits (1469), Expect = e-161, Method: Compositional matrix adjust. Identities = 287/411 (69%), Positives = 334/411 (81%) Query: 7 QETFIQTNFADRIGGANYGKDTAIYKFEKIKRAKASAKQDFPNIELIDMGVGEPDEMADE 66 E+FIQ FA+RIGG+N+GK+T +YKFEKIKRAKA AK+ P++ELIDMGVGEPDE AD Sbjct: 1 MESFIQNMFAERIGGSNFGKETVLYKFEKIKRAKAKAKELHPDMELIDMGVGEPDEKADM 60 Query: 67 GIXXXXXXXXXXXXNRGYSDNGIPEFKAAAAAYLKEVFRVDGIDPVTEVVHSIGSKPALA 126 GI NRGY+DNGI EFK AAA YL+ V+ V I+P TEV H+IGSK ALA Sbjct: 61 GIIGTLAYEAGKDENRGYADNGIYEFKVAAAKYLERVYGVKEINPDTEVNHAIGSKSALA 120 Query: 127 MLPSCFINPGDITIMTVPGYPVLGTHTKYLGGQVFTVELKKENNFLPDLNSIPEDVARKA 186 +LP FINPGD+TIMTVPGYPVLGT TK+LGG+V+ V L KENNFLPDL+SIP D+ ++A Sbjct: 121 LLPYAFINPGDVTIMTVPGYPVLGTITKWLGGEVYNVPLLKENNFLPDLSSIPADIKKRA 180 Query: 187 KLLYLNYPNNPTGASATPEFFSEVVAWAKKYDVVVIHDAPYAALTYDGMKPLSFLSVPGA 246 KL+YLNYPNNP GA AT EFF EVV +A K +++V+HDA YAAL +DG KPLSFLSV GA Sbjct: 181 KLMYLNYPNNPCGAVATKEFFEEVVEFAAKNNIIVVHDAAYAALVFDGYKPLSFLSVDGA 240 Query: 247 KDVGVELHSLSKSYNMTGWRIGFVAGNPLVVKAFSDVKDNNDSGQFIAIQKAAAYGLEHP 306 K+VGVE+HSLSK+YNMTGWR+ FVAGN LVVKAF+ VKDNNDSGQF AIQKA Y LEHP Sbjct: 241 KEVGVEIHSLSKAYNMTGWRLAFVAGNELVVKAFAAVKDNNDSGQFKAIQKAGIYALEHP 300 Query: 307 EITEAIAAKYSRRHNMLVDALNSLGFSAEKPKGSFFLYVAAPKGIKGGRRFESGEDFSQF 366 EITE I KYSRRH++LV L LGF A+KPKGSF+LYV PKGIK GRRFE+ E+FS++ Sbjct: 301 EITEKINEKYSRRHDLLVKTLRELGFDAQKPKGSFYLYVEIPKGIKNGRRFETAEEFSEY 360 Query: 367 LIREKLISTVPWDDAGPFVRFSVTFIAKGEEEEKRVISEIQRRLSDVEFEF 417 LI EK ISTVPWDDAG FVRFSVTF AK E+E RV+ E++RRLSDVEFEF Sbjct: 361 LITEKCISTVPWDDAGHFVRFSVTFEAKTPEDEIRVMEELKRRLSDVEFEF 411 >B9MPB1.1 B9MPB1_ANATD Aminotransferase class I and II Length = 411 Score = 563 bits (1452), Expect = e-159, Method: Compositional matrix adjust. Identities = 283/411 (68%), Positives = 333/411 (81%) Query: 7 QETFIQTNFADRIGGANYGKDTAIYKFEKIKRAKASAKQDFPNIELIDMGVGEPDEMADE 66 E+FIQ FA+RIGG+ +GK+T +YKFEKIKRAKA AK+ P++ELIDMGVGEPDE AD Sbjct: 1 MESFIQNMFAERIGGSKFGKETILYKFEKIKRAKAKAKELHPDMELIDMGVGEPDEKADM 60 Query: 67 GIXXXXXXXXXXXXNRGYSDNGIPEFKAAAAAYLKEVFRVDGIDPVTEVVHSIGSKPALA 126 GI NRGY+DNGI EFK AAA YL+ V+ V GI+P TEV H+IGSK ALA Sbjct: 61 GIIGTLAYEAGKDENRGYADNGIYEFKVAAAKYLERVYGVKGINPDTEVNHAIGSKSALA 120 Query: 127 MLPSCFINPGDITIMTVPGYPVLGTHTKYLGGQVFTVELKKENNFLPDLNSIPEDVARKA 186 +LP FINPGD+TIMTVPGYPVLGT TK+LGG+V+ V L KENNFLPDL+SIP D+ ++A Sbjct: 121 LLPYAFINPGDVTIMTVPGYPVLGTITKWLGGEVYNVPLLKENNFLPDLSSIPADIRKRA 180 Query: 187 KLLYLNYPNNPTGASATPEFFSEVVAWAKKYDVVVIHDAPYAALTYDGMKPLSFLSVPGA 246 KL+YLNYPNNP GA AT EFF EVV +A + +++V+HDA YAAL +DG KPLSFLSV GA Sbjct: 181 KLMYLNYPNNPCGAVATKEFFEEVVKFAMENNIIVVHDAAYAALVFDGYKPLSFLSVEGA 240 Query: 247 KDVGVELHSLSKSYNMTGWRIGFVAGNPLVVKAFSDVKDNNDSGQFIAIQKAAAYGLEHP 306 K+VGVE+HSLSK+YNMTGWR+ FVAGN LVVKAF+ VKDNNDSGQF AIQKA Y LEHP Sbjct: 241 KEVGVEIHSLSKAYNMTGWRLAFVAGNELVVKAFAAVKDNNDSGQFKAIQKAGIYALEHP 300 Query: 307 EITEAIAAKYSRRHNMLVDALNSLGFSAEKPKGSFFLYVAAPKGIKGGRRFESGEDFSQF 366 EITE I KYSRRH++LV L LGF A+KPKGSF+LYV PKGIK GRRFE+ E+FS++ Sbjct: 301 EITEKINEKYSRRHDLLVKTLRDLGFDAQKPKGSFYLYVEIPKGIKNGRRFETAEEFSEY 360 Query: 367 LIREKLISTVPWDDAGPFVRFSVTFIAKGEEEEKRVISEIQRRLSDVEFEF 417 LI EK ISTVPWDDAG FVR SVTF AK E+E +V+ E+++RLSDVEFEF Sbjct: 361 LITEKCISTVPWDDAGHFVRLSVTFEAKTPEDEIKVMEELKKRLSDVEFEF 411 >A6UX48.1 A6UX48_META3 Aminotransferase class I and II Length = 416 Score = 541 bits (1395), Expect = e-152, Method: Compositional matrix adjust. Identities = 261/415 (62%), Positives = 318/415 (76%), Gaps = 6/415 (1%) Query: 8 ETFIQTNFADRIGGANYGKDTAIYKFEKIKRAKASAKQDFPNIELIDMGVGEPDEMADEG 67 E++IQ FA+RIGG N+GKD IYKFEKIKRAK AK +P+IELIDMGVGEPDEMAD+ Sbjct: 2 ESYIQNLFAERIGGKNFGKDDVIYKFEKIKRAKMEAKAKYPDIELIDMGVGEPDEMADKE 61 Query: 68 IXXXXXXXXXXXXNRGYSDNGIPEFKAAAAAYLKEVFRVDGIDPVTEVVHSIGSKPALAM 127 + NRGY+DNGI E K A A Y+KEV+ VDGIDP TEV+HS+GSKPALA Sbjct: 62 VIETLYNEAKKHENRGYADNGIDELKEAVAKYMKEVYGVDGIDPKTEVIHSMGSKPALAY 121 Query: 128 LPSCFINPGDITIMTVPGYPVLGTHTKYLGGQVFTVELKKENNFLPDLNSIPEDVARKAK 187 + S FINPGD+ +MTVPGYPV THT++ GG+V+ + L +EN FLPDL SIP+D+ KAK Sbjct: 122 ITSVFINPGDVILMTVPGYPVSATHTEWYGGEVYNMPLLEENKFLPDLKSIPDDIKEKAK 181 Query: 188 LLYLNYPNNPTGASATPEFFSEVVAWAKKYDVVVIHDAPYAALTYDGMKPLSFLSVPGAK 247 +LYLNYPNNPTGA AT EF+ EVV +AK+ +++V+ DA Y ALTY+G +PLSFLS+ GAK Sbjct: 182 ILYLNYPNNPTGAQATKEFYEEVVQFAKENNIIVVQDAAYGALTYNG-EPLSFLSIDGAK 240 Query: 248 DVGVELHSLSKSYNMTGWRIGFVAGNPLVVKAFSDVKDNNDSGQFIAIQKAAAYGLEHPE 307 DVGVE+HS SK+YNMTGWR+ FV GN L+V F+ VKDN DSGQFI IQKA Y LEHPE Sbjct: 241 DVGVEIHSFSKAYNMTGWRLAFVVGNDLIVSGFATVKDNFDSGQFIPIQKAGIYCLEHPE 300 Query: 308 ITEAIAAKYSRRHNMLVDALNSLGFSAEKPKGSFFLYVAAPKGIKGGRRFESGEDFSQFL 367 ITE AKY RR N +V+ LN +GF A+ P G+F+LY+ APKG K G F SGE+FS +L Sbjct: 301 ITERTRAKYERRLNKMVNLLNEVGFDAKMPGGTFYLYIKAPKGTKCGHIFNSGEEFSHYL 360 Query: 368 IREKLISTVPWDDAGPFVRFSVTFIA-----KGEEEEKRVISEIQRRLSDVEFEF 417 I+EKL+STVPWDDAG FVR + F A EEEE R+++E++RRLSDVEF F Sbjct: 361 IKEKLVSTVPWDDAGHFVRMAACFPAFKDGEVSEEEEDRILNEVKRRLSDVEFIF 415 >A8TE48.1 A8TE48_METVO Aminotransferase class I and II Length = 425 Score = 527 bits (1358), Expect = e-148, Method: Compositional matrix adjust. Identities = 254/415 (61%), Positives = 313/415 (75%), Gaps = 6/415 (1%) Query: 8 ETFIQTNFADRIGGANYGKDTAIYKFEKIKRAKASAKQDFPNIELIDMGVGEPDEMADEG 67 E++IQ FADRIGG N+GK+ IYKFEKIKRAK AK+ +PNIELIDMGVGEPDEMAD Sbjct: 12 ESYIQNLFADRIGGNNFGKEDVIYKFEKIKRAKNEAKKKYPNIELIDMGVGEPDEMADAK 71 Query: 68 IXXXXXXXXXXXXNRGYSDNGIPEFKAAAAAYLKEVFRVDGIDPVTEVVHSIGSKPALAM 127 + NRGYSDNG K Y+++VF V GI+P TEV+HSIGSKPALA Sbjct: 72 VVETLYEEAKKPENRGYSDNGTQALKDEIPIYMEKVFGVKGINPETEVIHSIGSKPALAY 131 Query: 128 LPSCFINPGDITIMTVPGYPVLGTHTKYLGGQVFTVELKKENNFLPDLNSIPEDVARKAK 187 + S FINPGDIT+MT PGYPV THTK+ GG+V+ +ELK+EN FLPDL SIP+D+ +KAK Sbjct: 132 ITSVFINPGDITLMTTPGYPVTATHTKWYGGEVYNLELKEENGFLPDLKSIPDDIKQKAK 191 Query: 188 LLYLNYPNNPTGASATPEFFSEVVAWAKKYDVVVIHDAPYAALTYDGMKPLSFLSVPGAK 247 +LYLNYPNNPTGA AT EF+ E + +AK+ +++++ DA YAALTY G KPLSFLSV GAK Sbjct: 192 ILYLNYPNNPTGAQATVEFYKEAIEFAKENNILIVQDAAYAALTY-GEKPLSFLSVEGAK 250 Query: 248 DVGVELHSLSKSYNMTGWRIGFVAGNPLVVKAFSDVKDNNDSGQFIAIQKAAAYGLEHPE 307 DVGVE+HS SK+YNMTGWR+ FV GN L+V+ F+ VKDN DSGQFI IQKA Y L HPE Sbjct: 251 DVGVEIHSFSKAYNMTGWRLAFVVGNELIVRGFAAVKDNYDSGQFIPIQKAGIYCLRHPE 310 Query: 308 ITEAIAAKYSRRHNMLVDALNSLGFSAEKPKGSFFLYVAAPKGIKGGRRFESGEDFSQFL 367 ITEA AKY RR +V+ L LGF+A+ P G+F+LYV AP G K G +F + E+FSQ+L Sbjct: 311 ITEATRAKYERRLQKMVNMLKELGFNAQMPGGTFYLYVKAPIGTKDGAKFANAEEFSQYL 370 Query: 368 IREKLISTVPWDDAGPFVRFSVTFIA-----KGEEEEKRVISEIQRRLSDVEFEF 417 I+EKLISTVPWDD G ++R + F A E++E +++E++RRLSDVEF F Sbjct: 371 IKEKLISTVPWDDVGNYIRMAACFSAFEDGKLSEKKEDEILNEVKRRLSDVEFVF 425 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.136 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,511,967,377 Number of extensions: 108941855 Number of successful extensions: 263647 Number of sequences better than 1.0e-05: 7152 Number of HSP's gapped: 254752 Number of HSP's successfully gapped: 7160 Length of query: 417 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 279 Effective length of database: 1,760,596,133 Effective search space: 491206321107 Effective search space used: 491206321107 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 132 (55.5 bits)