BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0263.0016.p (2047 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A7GTG0.1 A7GTG0_BACCN Amino acid adenylation domain 2013 0.0 B9E1U3.1 B9E1U3_CLOK1 Putative uncharacterized protein 1899 0.0 A5N8D6.1 A5N8D6_CLOK5 Predicted nonribosomal peptide synthetase 1898 0.0 Q3M5Z7.1 Q3M5Z7_ANAVT Amino acid adenylation EC=5.1.1.11 1402 0.0 B0JJG2.1 B0JJG2_MICAN Amino acid adenylation 952 0.0 >A7GTG0.1 A7GTG0_BACCN Amino acid adenylation domain Length = 2031 Score = 2013 bits (5216), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1006/2053 (49%), Positives = 1354/2053 (65%), Gaps = 47/2053 (2%) Query: 12 SSGTNQAVYQLVSNVTGHRIEDLNSDMYLEDDLGLDSIKMITLMNELIGLVPAEQMDDFT 71 S +VY+L++NVTGHR+EDL++DMYLE DLGLDSIKMITLMNELI L+P EQ++DF Sbjct: 7 SEKDKMSVYKLIANVTGHRVEDLDTDMYLESDLGLDSIKMITLMNELIKLIPQEQVEDFM 66 Query: 72 AAYPVTVLMGLQTVGELVQIFEEWEHARXXXXXXXXXXXXXXXXXXDTWPEPAAVQIHSA 131 + P+ VLM LQT+ +++ I +W+ A D+ + + Sbjct: 67 SKNPIQVLMSLQTIHDIIDIMVKWK-AEQHATNGLSSSISSVIEINDSDDKHKKI---DE 122 Query: 132 PPDLREQLKIEVCRLISGITGHKSEDLHTDMDLERDLGLDSIKMITLMSEMVSLLPADSS 191 P EQ + +IS +TGH DL+ + LE DLG+DSIKMITLM+E++ L+P Sbjct: 123 PNIYDEQTIASIFSVISNVTGHNVADLNVGLYLESDLGIDSIKMITLMNELMKLIPQGQL 182 Query: 192 GGHSESNLVTSLMSMHTVGDIVEMLAVRNGGNSGTLAVAGDVNTIEAEIPENEPEFLEIL 251 +E + V LM++ T+GDI + G S ++ + + +E + + LE++ Sbjct: 183 QDFTEKHPVQFLMNLQTIGDIACIFTKWKGELSTSVPLNHNSGYTNSE----KVDTLEMI 238 Query: 252 HSQYLFLITYLSVANLTITSGVRVRGRLDADNLRKSWGELIRRHPILRAVFITEPANASL 311 H+QY FLI+Y +V+ +TI+SGV+V+G LD + L+++W EL+ RHPIL++VF + S Sbjct: 239 HAQYPFLISYFAVSTITISSGVKVKGSLDTNLLKQAWQELVGRHPILQSVFQVQQGAESF 298 Query: 312 KGYRLQLLKAAVPPEIPVLDIRHLDEQARLRWISERFEASLNEKLDITRWPLHSLSVIQT 371 K Y L ++K PEIPVLD+RHL + + I FE SLN+K++I +WPLH + VI+T Sbjct: 299 KEYCLNIVKEIELPEIPVLDLRHLAVDMQKKAIKHHFETSLNKKINIFQWPLHFVEVIRT 358 Query: 372 ADLEYELILDINHMISDGLGNQQILRELLEIYGAESHNKAARLRPALPAGEYNRIVSEIN 431 D EYE++L INH ISDG+GNQQI+RELLE+Y A+ H+ + L ++ A EYNRIVS++N Sbjct: 359 RDEEYEIVLSINHTISDGIGNQQIIRELLELYSAKVHHTPSGLTESISASEYNRIVSQMN 418 Query: 432 AWNAPEEMEALDRYLQQQGRGAYFFNPXXXXXXXXXXXXXXXVIHSRKYWVGEEITARLI 491 W E + L+++L QGR YFFNP ++K+W+ EE+T L+ Sbjct: 419 EWVDEIEQKRLEQFLNHQGREQYFFNPYQVGKEAMTKPFAGVTTKTQKFWLDEELTTSLM 478 Query: 492 ASTKTWRTSLFILLVSAYLKTIRQQGEERNRIILNLPTGGRLYPHTDASEVLSAFAQNLA 551 K TSLF LL+SAY+KT++Q E +ILN+PT G++YP+ DA+ VL AFAQNLA Sbjct: 479 TCAKLLETSLFTLLLSAYIKTVKQYDVENKNLILNIPTSGKVYPNVDATGVLGAFAQNLA 538 Query: 552 LSFTCGDANEEWESLINRTHEEFTNQLSSGIDRAQTYRAAQYAKDTIHLQNGVMPEAVAS 611 L+F + +W++ +N+ E ++SGIDRAQT++AA+ AK+ I LQ+G + + VA Sbjct: 539 LTFDY--THTDWKTFVNKIDTEMKRNVTSGIDRAQTHKAAKEAKEYIQLQDGKLSDTVAQ 596 Query: 612 MIRSTLKSNLYLSFVGNTSIHTRYGDYEVYDYEAYTGTNPGTIDCLAELFQGRLMITANY 671 +RSTLKSNLY SF+GNT++ YG EVYDYEAYT TN ID + ELF G++MIT+NY Sbjct: 597 FVRSTLKSNLYFSFIGNTNLKKNYGGLEVYDYEAYTCTNYRAIDNVMELFHGKIMITSNY 656 Query: 672 DSSFFDDDYIGEHMDRFMDNLSQLAGMGP-----VGKPVLAGEDTEGPHSAEIRERLYGI 726 D FF++ +I E++D F+ N+ L + +P++ ED AE++ + I Sbjct: 657 DGDFFNESFIREYIDAFIYNIKDLVAYAQSIHQNIRQPIIINED------AEVKGAVCNI 710 Query: 727 VRDISGTALDEEALFKDMEAELGMDSLQRIRLITRLGKVFGHADKGALLECRTLNEIITH 786 V ++ + + KD++ GMDSLQRIR+ITR+ K FG+ D+ + CRT+ E+++ Sbjct: 711 VEEVCARPILLGDMDKDLDVVFGMDSLQRIRVITRIEKEFGNCDQEKIFGCRTIREMVSI 770 Query: 787 ISHVNNAIEPADRD--SAAEIPYLHISRQCKATPDAVAILDGTREVTYRELDEQSNRLAH 844 IS E R + E+PY HI QCK TP A+AI G +VTY ELD SNRLAH Sbjct: 771 IS------EKKGRQLVESVEVPYFHIMEQCKQTPQAIAIEYGDEKVTYSELDHLSNRLAH 824 Query: 845 YLISQGVRSQSLVGILTFPGRLMLTGILGILKAGAAYVPLDPMYPADRIEYIAEHAQLSI 904 L +GV+ L+GI+T PG ML G+LGILK+GAAYVPLDP YP +RI YI HA++ I Sbjct: 825 CLREKGVKRGDLIGIMTNPGPYMLIGMLGILKSGAAYVPLDPSYPLNRIHYILNHAKVEI 884 Query: 905 LLTEQSLQKQTDPIVQKSPSIRKVVYLDE-GYEVHGHFEQTGTEVWQSCPAGDLRVDSAP 963 LL+EQ+ + Q ++QK + VVY+D +V +Q E W S ++ + P Sbjct: 885 LLSEQAFKTQISQLLQKQTLMDIVVYIDPWETDVQMSLQQIEKETWMSYSHQEIERINHP 944 Query: 964 HDLMVVLYTSGSTGKPKGVMLNHRGYMNRLEWHQQTFCLQLGERVAQKTSCCFDISVWEL 1023 D+M VLYTSGSTG PKGV+L HRGYMNRL WHQ F L+LGERVAQKTSCCFD+S+WEL Sbjct: 945 DDIMTVLYTSGSTGHPKGVVLQHRGYMNRLNWHQDIFKLKLGERVAQKTSCCFDVSIWEL 1004 Query: 1024 LWPLMYGGTVCPVRQEIVKNPWSLARWMTDTGINVMHFVPSLFGEFVDSLEDESYTFPAL 1083 WPLM+GGTVCPV +++V+NPW LARW+ +T I+VMHFVPSLFGEF+ S+ED++Y FP L Sbjct: 1005 FWPLMFGGTVCPVHKDVVRNPWRLARWIIETRISVMHFVPSLFGEFIHSIEDKAYHFPNL 1064 Query: 1084 RWLIFSGEGLPLRPVQKWMDRYGNKTKLANLYGPTEASIDVTYHIISGRPGSAG-EMSIP 1142 RWLIFSGE LP ++KW+ YG T LANLYGPTEASIDVTYHII G G E SI Sbjct: 1065 RWLIFSGEALPASVIKKWLQTYGESTGLANLYGPTEASIDVTYHIIEGNQILDGSENSIL 1124 Query: 1143 IGKPIPGVYIKNLDEHMREVPXXXXXXXXXXXXQLAKGYLYNPEKTREAFHPNPFPEIPG 1202 IGKP+ V++K LDE MREVP QLAKGYL NP KT+EAF N F EIPG Sbjct: 1125 IGKPLNNVHVKILDEDMREVPKGIIGELWIGGIQLAKGYLNNPSKTKEAFKMNLFSEIPG 1184 Query: 1203 EFIYRTGDLTVKRADGSYEYHGRTDNQVKLRGFRVELGEIEAVLGSHDHVAEAAVIVTQP 1262 +++YRTGDL R DG+ EYHGR DNQVK+RGFRVELGEIEAV+ SH V E V+ Sbjct: 1185 DYLYRTGDLVKMRPDGNLEYHGRIDNQVKVRGFRVELGEIEAVIHSHSSVKEVGVVTLDS 1244 Query: 1263 APGQQLLLACLAGKQVPDQEIKNFAVRKLPYYMIPHRVEWLPRLPKNPNGKLDRKA-LSV 1321 + L+AC+ G + +QE+K F +KLPYYMIPHR+E+L LPKN NGKLDRK LS+ Sbjct: 1245 PEEHKQLIACVVGNCLEEQELKRFIGQKLPYYMIPHRIEFLSSLPKNHNGKLDRKVMLSI 1304 Query: 1322 MFSGTGQAPQTPQASEMQIPPAAEREPLSAGDLLPLAPAQSWLMNYFDDPYCWAGYTRFL 1381 + + + Q + E ++ D++PL+PAQ WLMNYF+ PY W GYTRFL Sbjct: 1305 LQTKKKEMRQDVSSV------VTETAIVTKDDVIPLSPAQQWLMNYFEHPYRWTGYTRFL 1358 Query: 1382 YKQPLDFQQFKQAVMMLNRRHDALRSILERKDNGFEQRFLQGELGGNVDFYDGSHMEEAE 1441 YKQ +D F +A+ +L RHDALRS++ +++ G+ QR L + + + YDG+ M+E E Sbjct: 1359 YKQDIDITTFNKALNILVNRHDALRSVVTKENGGWVQRILPQGISISAETYDGTQMDENE 1418 Query: 1442 RNEEIGAILTEAIQGFRVDQWPLWRIIVVQVSEAVYEIAAVGHHLISDVVTNQLLLQEVW 1501 R + ++ E IQ F + +WPL R+I+++VS+++Y+I VGHHLISDV+TNQLL +E+W Sbjct: 1419 RERSLKNLIDEVIQTFEIGEWPLLRVIIMKVSKSIYDITVVGHHLISDVITNQLLFKEMW 1478 Query: 1502 QIYASLSPGARHISLPDAKPFADFVRAVQEKKRIHGKEYAGYWSTHFP-PESVCRLPADF 1560 QIY L + LP K + +FV V+EKK+ + EY YW FP E +PAD Sbjct: 1479 QIYGQLLSSNEEVKLPTVKSYKEFVLLVEEKKKENLVEYVEYWKGQFPMHEHSFYIPADL 1538 Query: 1561 IKGPNDEQSAATQRFTFDREQTSLLLTRAKKHFNSNVYPILLAPLYKELSVFFGQPEVVV 1620 G NDEQS + F ++ T++LL +AK +F SNVY +LLAPLYK LS + Q +VVV Sbjct: 1539 NLGTNDEQSTCMESFLIEKSATAILLGKAKDYFKSNVYSMLLAPLYKMLSSLYNQSKVVV 1598 Query: 1621 SHRVHGRELSGGQNFMQTPGNFAVNFPLGINVEKGSHWSNLIASIRKGLENVPLGGVSYD 1680 SHR HGR + Q F TPGNFA+N+PL I + K W ++ +I+ + VP+GG+SYD Sbjct: 1599 SHRTHGRNVENQQIFFDTPGNFAINYPLSITINKEDTWLEVVHNIKNNMNEVPMGGISYD 1658 Query: 1681 LVSENLPRYMYPDVKLTPIRANYLGNRDAPRLPGLEFSREGMDRRLSLPGQKRISVIEFF 1740 LV+ LP YMYPD KLTPIRANYLGNRD P EFS+E MDRR S+PGQKRIS+IEFF Sbjct: 1659 LVAPYLPSYMYPDTKLTPIRANYLGNRDMPDFKVFEFSKENMDRRFSMPGQKRISMIEFF 1718 Query: 1741 FSIEEGKLTVEIEYSANLYAAATIQSLAEQYREQALELLESI------QDTPVL--PPAP 1792 FSI EGKL V IEYS NLY ++TI+ L E+Y +Q +L +I TP++ + Sbjct: 1719 FSIVEGKLQVCIEYSKNLYHSSTIRKLGEEYMKQLDMMLATIDTGTKVNQTPMVMSNSSG 1778 Query: 1793 RKGLLANKVAVITXXXXXXXXXXALSMAGEGADIVLVSRSGQQLRETADEIRRLGXXXXX 1852 LLA+KVA++T A+SMA EGA + +VSR+ QL ETA EIR+LG Sbjct: 1779 EIRLLADKVAIVTGGGRGIGRAIAISMAQEGASVAIVSRTEHQLDETACEIRKLGIEPLV 1838 Query: 1853 XXXXXXXXXXXNKAVEQIIGSFGRIDILVNGAGITGMAAMADMSPGVWESIIQVNLLGTY 1912 V+ + FG+IDI+VN AGIT + ++ D++ W+ II+VN+ GTY Sbjct: 1839 IPGDIGEWNDVQHIVKTVSKQFGKIDIVVNNAGITKVGSVTDVTSEEWKEIIRVNVFGTY 1898 Query: 1913 HFCYAVIPYLXXXXXXXXXXXXSDSSFIGYPMMSAYAASKHGVLGLTRALSEELKNSNIQ 1972 H C A IPYL SDSSFIGYP MSAYAASKHGVLGLT++L+EE+K NIQ Sbjct: 1899 HMCRATIPYLIEQKCGKIINIGSDSSFIGYPFMSAYAASKHGVLGLTKSLAEEMKPYNIQ 1958 Query: 1973 VNAVCPALVDTDMAPAAFKGRAIPPSGVADSVVFLASPRADYITGEAVQVYGKQDMHWFG 2032 VNAVCP+LV+TDMAP AFK +AIPP VA++V FLAS ++D ITGE+++VYGKQDM+WFG Sbjct: 1959 VNAVCPSLVNTDMAPKAFKNKAIPPEQVAETVKFLASAQSDCITGESIRVYGKQDMYWFG 2018 Query: 2033 AQQMQMLQAVQRR 2045 ++Q+ ML+A+ + Sbjct: 2019 SEQIPMLKAILNK 2031 Score = 84.3 bits (207), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 40/83 (48%), Positives = 58/83 (69%) Query: 135 LREQLKIEVCRLISGITGHKSEDLHTDMDLERDLGLDSIKMITLMSEMVSLLPADSSGGH 194 L E+ K+ V +LI+ +TGH+ EDL TDM LE DLGLDSIKMITLM+E++ L+P + Sbjct: 6 LSEKDKMSVYKLIANVTGHRVEDLDTDMYLESDLGLDSIKMITLMNELIKLIPQEQVEDF 65 Query: 195 SESNLVTSLMSMHTVGDIVEMLA 217 N + LMS+ T+ DI++++ Sbjct: 66 MSKNPIQVLMSLQTIHDIIDIMV 88 >B9E1U3.1 B9E1U3_CLOK1 Putative uncharacterized protein Length = 1901 Score = 1899 bits (4920), Expect = 0.0, Method: Compositional matrix adjust. Identities = 938/1930 (48%), Positives = 1275/1930 (66%), Gaps = 67/1930 (3%) Query: 139 LKIEVCRLISGITGHKSEDLHTDMDLERDLGLDSIKMITLMSEMVSLLPADSSGGHSESN 198 +K++V LIS +TGH+ EDL +M LE DLG+DSIKM+TLM++++ L+P + + Sbjct: 17 MKVQVYELISNVTGHRIEDLDCEMFLEGDLGIDSIKMVTLMNQLMKLVPTEGLDEFTSMY 76 Query: 199 LVTSLMSMHTVGDIVEMLAVRNGGNSGTLAVAGDVNTIEAEIPENEPEFLEILHSQYLFL 258 + LMS+ T+G+IV + G E ++E + L IL++QY FL Sbjct: 77 PIARLMSLQTIGEIVLIFEEFYNG---------------KESSQSEKDNLVILNAQYPFL 121 Query: 259 ITYLSVANLTITSGVRVRGRLDADNLRKSWGELIRRHPILRAVFITEPANASLKGYRLQL 318 ++Y SV LTI SGV++ G L + L++SW EL+RRHP LRA F S K Y L++ Sbjct: 122 VSYWSVGTLTICSGVKIEGPLYLNQLQESWLELVRRHPSLRAEFDVCEGAKSFKDYSLKV 181 Query: 319 LKAAVPPEIPVLDIRHLDEQARLRWISERFEASLNEKLDITRWPLHSLSVIQTADLEYEL 378 PEI V DIRH+ QA+ + I++ E LN DI +PLH VIQ D EYEL Sbjct: 182 FSNPTLPEIEVQDIRHMSAQAKSQRINQIIEEILNNSFDIFVYPLHRFMVIQINDTEYEL 241 Query: 379 ILDINHMISDGLGNQQILRELLEIYGAESHNKAARLRPALPAGEYNRIVSEINAWNAPEE 438 IL NH++SDGLGNQQILRE+LEIY A+ + +L +L G+YN+++SEIN WN PEE Sbjct: 242 ILANNHLVSDGLGNQQILREILEIYAAKIQGVSVKLSESLSLGDYNKVISEINNWNDPEE 301 Query: 439 MEALDRYLQQQGRGAYFFNPXXXXXXXXXXXXXXXVIHSRKYWVGEEITARLIASTKTWR 498 + LD Y Q G+ Y FNP + ++KYW+GE IT L+ +K WR Sbjct: 302 NKNLDSYSQVCGKAKYSFNPFGSGNSDNEFAQ----VKTKKYWIGENITRLLMDKSKAWR 357 Query: 499 TSLFILLVSAYLKTIRQQGEERNRIILNLPTGGRLYPHTDASEVLSAFAQNLALSFTCGD 558 SLF L+VSA+LK+I Q E+ +IILNLPTGG++YP+ DA+ ++ FAQN+++SF + Sbjct: 358 VSLFTLMVSAHLKSITQLDEDGEQIILNLPTGGKVYPNIDATGLIGCFAQNMSVSFNSKE 417 Query: 559 ANEEWESLINRTHEEFTNQLSSGIDRAQTYRAAQYAKDTIHLQNGVMPEAVASMIRSTLK 618 A+E+W +L+ R +E +++SSGIDRAQTY AA+ AKD L++G M + A+ +RS+LK Sbjct: 418 ADEDWVTLVMRVDKEIKDKISSGIDRAQTYIAAKMAKDEDMLEDGKMAKTTAAFVRSSLK 477 Query: 619 SNLYLSFVGNTSIHTRYGDYEVYDYEAYTGTNPGTIDCLAELFQGRLMITANYDSSFFDD 678 SNLYLSFVG+T I YG+ ++ DYEAYT TN G ID + ELFQ ++ I++NYDS F + Sbjct: 478 SNLYLSFVGDTHIKEEYGNLKIVDYEAYTSTNSGAIDNIIELFQNQIFISSNYDSLHFHE 537 Query: 679 DYIGEHMDRFMDNLSQLAGMGPVGKPVLAGEDT----EGPHSAEIRERLYGIVRDISGTA 734 D I + +F+DNL LA + ED E + L I +I T Sbjct: 538 DDINLLIRKFIDNLYFLANYK------MENEDKVLRLEVSEDKMLLGELQKIAEEICCTT 591 Query: 735 LDEEALFKDMEAELGMDSLQRIRLITRLGKVFGHADKGALLECRTLNEIITHISHVNNAI 794 + EE + KD+E + G+DSLQ IR+I RL K+ DK +L CRTL+E+ + N ++ Sbjct: 592 ICEEDVHKDLETDFGIDSLQCIRIIRRLCKLHEGVDKNSLFGCRTLSEMALLVEK-NQSL 650 Query: 795 EPADRDSAAEIPYLHISRQCKATPDAVAILDGTREVTYRELDEQSNRLAHYLISQGVRSQ 854 +IPY I +QC+ATPDA+AI+ +TY+ELD SNR+A+YL SQGV+ Sbjct: 651 TGNYSGEEEQIPYRQIVKQCRATPDAIAIMYKDENITYKELDHISNRIANYLKSQGVKRG 710 Query: 855 SLVGILTFPGRLMLTGILGILKAGAAYVPLDPMYPADRIEYIAEHAQLSILLTEQSLQKQ 914 SLVGI+ FPG +ML G++GI+KAGAAYVP+DP YP +R++YI ++ + ILLTE L+ Sbjct: 711 SLVGIMVFPGPIMLFGMMGIMKAGAAYVPVDPSYPTERVQYILNNSDIEILLTEHGLKTS 770 Query: 915 TDPIVQKSPSIRKVVYLDEGYEVHG--HFEQTGTEVWQSCPAGDLRVDSAPHDLMVVLYT 972 + ++++ I+ ++YLD G + +++Q E W + G+ V ++P DLM VLYT Sbjct: 771 LEQLIKEDSVIKALMYLDYGTFLDSIYNYKQILKEQWMAANDGEPEVINSPDDLMTVLYT 830 Query: 973 SGSTGKPKGVMLNHRGYMNRLEWHQQTFCLQLGERVAQKTSCCFDISVWELLWPLMYGGT 1032 SGSTG PKGVML HRGYMNRL+WHQ TF L+ GERVAQKTSCCFDISVWEL WPLMYGG Sbjct: 831 SGSTGNPKGVMLGHRGYMNRLKWHQDTFKLKPGERVAQKTSCCFDISVWELFWPLMYGGI 890 Query: 1033 VCPVRQEIVKNPWSLARWMTDTGINVMHFVPSLFGEFVDSLEDESYTFPALRWLIFSGEG 1092 VCP +E VKNPWSL +W+ DT IN+MHFVPSLFGEFV++LED+ Y+F LRWLIFSGE Sbjct: 891 VCPASKETVKNPWSLGKWLIDTKINIMHFVPSLFGEFVNALEDDDYSFKDLRWLIFSGEA 950 Query: 1093 LPLRPVQKWMDRYGNKTKLANLYGPTEASIDVTYHIISGRPGSAGEMSIPIGKPIPGVYI 1152 LP+ +QKW+D++G LANLYGPTEASIDVT HII RPG GE SIPIGKPI V+I Sbjct: 951 LPMATIQKWIDKHGLSIGLANLYGPTEASIDVTCHIIDKRPGINGENSIPIGKPIDNVFI 1010 Query: 1153 KNLDEHMREVPXXXXXXXXXXXXQLAKGYLYNPEKTREAFHPNPFPEIPGEFIYRTGDLT 1212 KNLDE M+E+P QL+ GY+ N +KT EAF PNPF ++PG+++YRTGDLT Sbjct: 1011 KNLDEDMKELPDGEMGELWIGGIQLSSGYMNNKQKTEEAFKPNPFKDVPGDYLYRTGDLT 1070 Query: 1213 VKRADGSYEYHGRTDNQVKLRGFRVELGEIEAVLGSHDHVAEAAVIVTQPAPGQQLLLAC 1272 +R DGSYEYHGR DNQVK+RGFRVELGEIEAVLG+H V E AVI GQ+ L A Sbjct: 1071 SRRQDGSYEYHGRKDNQVKIRGFRVELGEIEAVLGTHPCVNETAVIAVDYIQGQKQLFAW 1130 Query: 1273 LAGKQVPDQEIKNFAVRKLPYYMIPHRVEWLPRLPKNPNGKLDRKALSVMFSGTGQAPQT 1332 ++G +V D E+K +KLPYYM+PHR EW+ LPK PNGKLDRK L+ Sbjct: 1131 VSGNKVDDSELKRCITKKLPYYMVPHRFEWVTVLPKTPNGKLDRKVLN------------ 1178 Query: 1333 PQASEMQIPPAAEREPLSAGDLLPLAPAQSWLMNYFDDPYCWAGYTRFLYKQPLDFQQFK 1392 + S+ ++ + L + +PL+PAQ+WLMNYFD PY W GYTRFLYKQPLD+ F Sbjct: 1179 -ELSQRKLKGNVVEDALISE--IPLSPAQNWLMNYFDYPYQWTGYTRFLYKQPLDYNLFN 1235 Query: 1393 QAVMMLNRRHDALRSILERKDNGFEQRFLQGELGGNV--DFYDGSHMEEAERNEEIGAIL 1450 +A+ +L HD LRS+L K ++Q+FL LG NV DFYDGSHME ER++E+ ++ Sbjct: 1236 KALSILTDNHDVLRSVLVNKGEKWQQKFL--PLGQNVEADFYDGSHMERKERDKEVKNLI 1293 Query: 1451 TEAIQGFRVDQWPLWRIIVVQVSEAVYEIAAVGHHLISDVVTNQLLLQEVWQIYASLSPG 1510 + I +VD+WPLW+++VV+V+ ++Y+I+ +GHHLISDV+TNQLL +++W+IY L Sbjct: 1294 DKIILDLKVDKWPLWKVVVVRVNSSLYDISVIGHHLISDVITNQLLFKDIWKIYRQLIL- 1352 Query: 1511 ARHISLPDAKPFADFVRAVQEKKRIHGKEYAGYWSTHFPPESVC-RLPADFIKGPNDEQS 1569 I L +K + DF+ V E+K+ G E+ YW FP E ++P DF G N EQS Sbjct: 1353 TEDIKLEKSKSYRDFILRVNEEKKNKGLEFVDYWKKQFPSEFYSFKIPEDFNLGSNTEQS 1412 Query: 1570 AATQRFTFDREQTSLLLTRAKKHFNSNVYPILLAPLYKELSVFFGQPEVVVSHRVHGREL 1629 A+++ F D+ +T LLT AKK F ++VYPILLAPLYK L + + +VVSHR++GR+L Sbjct: 1413 ASSEMFILDKAKTQQLLTTAKKCFQTSVYPILLAPLYKMLQRLYNKSWIVVSHRMNGRDL 1472 Query: 1630 SGGQNFMQTPGNFAVNFPLGINVEKGSHWSNLIASIRKGLENVPLGGVSYDLVSENLPRY 1689 G F QT GNFA+N+PLG+ + W+ ++ I + VP+ GVSYDL+S+NLP Y Sbjct: 1473 -GNNIFFQTAGNFAINYPLGVTIGHNEDWNEIVNKITNAMNGVPMNGVSYDLISDNLPSY 1531 Query: 1690 MYPDVKLTPIRANYLGNRDAPRLPGLE-FSREGMDRRLSLPGQKRISVIEFFFSIEEGKL 1748 +YPD+ L IR+NYLGNRD P+ E FS++ +DRR S P QKRIS IEFF+SI G+L Sbjct: 1532 LYPDLNLASIRSNYLGNRDIPQYDTFEFFSKDDIDRRYSQPDQKRISSIEFFYSIVNGEL 1591 Query: 1749 TVEIEYSANLYAAATIQSLAEQYREQALELLESIQD------TPVLPP------APRKGL 1796 +EIEYS N+Y+ +TI+ L +Y +E++ I + L P + ++G Sbjct: 1592 NLEIEYSKNMYSESTIKHLGSKYMRAFMEMISYINNKKNPKYNSTLKPLSLIRGSKKEGF 1651 Query: 1797 LANKVAVITXXXXXXXXXXALSMAGEGADIVLVSRSGQQLRETADEIRRLGXXXXXXXXX 1856 L+NK ++T A+ MA EGA+I ++SR+ +L ETA EI+ +G Sbjct: 1652 LSNKSVIVTGGGRGIGKTIAIEMAKEGAEIAIISRTAGELEETAAEIKGIGSKVMTITTD 1711 Query: 1857 XXXXXXXNKAVEQIIGSFGRIDILVNGAGITGMAAMADMSPGVWESIIQVNLLGTYHFCY 1916 AV++I+ FG+ID+LVN AGIT MA D+ W+ I++VNL GTY+ CY Sbjct: 1712 ISSYNDICDAVKKIVSEFGKIDVLVNNAGITKMAPFTDIKEEEWKRIVEVNLFGTYNLCY 1771 Query: 1917 AVIPYLXXXXXXXXXXXXSDSSFIGYPMMSAYAASKHGVLGLTRALSEELKNSNIQVNAV 1976 IP+ SDSSFIGYP+MSAY+ASKHG++GLT++L+EE K SNIQVNA+ Sbjct: 1772 LTIPHFVKQKSGKIINLGSDSSFIGYPLMSAYSASKHGIIGLTKSLAEEFKASNIQVNAI 1831 Query: 1977 CPALVDTDMAPAAFKGRAIPPSGVADSVVFLASPRADYITGEAVQVYGKQDMHWFGAQQM 2036 CPA+VDT+MAP AFK A+ P VAD V+FL+S ++DYITGEA++++GKQDM+WFG+ + Sbjct: 1832 CPAMVDTNMAPGAFKKNAMSPKKVADLVLFLSSNKSDYITGEAIKIFGKQDMYWFGSHHI 1891 Query: 2037 QMLQAVQRRQ 2046 L+A ++ Sbjct: 1892 PALRAALSKR 1901 Score = 116 bits (290), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 51/81 (62%), Positives = 69/81 (85%) Query: 19 VYQLVSNVTGHRIEDLNSDMYLEDDLGLDSIKMITLMNELIGLVPAEQMDDFTAAYPVTV 78 VY+L+SNVTGHRIEDL+ +M+LE DLG+DSIKM+TLMN+L+ LVP E +D+FT+ YP+ Sbjct: 21 VYELISNVTGHRIEDLDCEMFLEGDLGIDSIKMVTLMNQLMKLVPTEGLDEFTSMYPIAR 80 Query: 79 LMGLQTVGELVQIFEEWEHAR 99 LM LQT+GE+V IFEE+ + + Sbjct: 81 LMSLQTIGEIVLIFEEFYNGK 101 >A5N8D6.1 A5N8D6_CLOK5 Predicted nonribosomal peptide synthetase Length = 1895 Score = 1898 bits (4917), Expect = 0.0, Method: Compositional matrix adjust. Identities = 938/1930 (48%), Positives = 1275/1930 (66%), Gaps = 67/1930 (3%) Query: 139 LKIEVCRLISGITGHKSEDLHTDMDLERDLGLDSIKMITLMSEMVSLLPADSSGGHSESN 198 +K++V LIS +TGH+ EDL +M LE DLG+DSIKM+TLM++++ L+P + + Sbjct: 11 MKVQVYELISNVTGHRIEDLDCEMFLEGDLGIDSIKMVTLMNQLMKLVPTEGLDEFTSMY 70 Query: 199 LVTSLMSMHTVGDIVEMLAVRNGGNSGTLAVAGDVNTIEAEIPENEPEFLEILHSQYLFL 258 + LMS+ T+G+IV + G E ++E + L IL++QY FL Sbjct: 71 PIARLMSLQTIGEIVLIFEEFYNG---------------KESSQSEKDNLVILNAQYPFL 115 Query: 259 ITYLSVANLTITSGVRVRGRLDADNLRKSWGELIRRHPILRAVFITEPANASLKGYRLQL 318 ++Y SV LTI SGV++ G L + L++SW EL+RRHP LRA F S K Y L++ Sbjct: 116 VSYWSVGTLTICSGVKIEGPLYLNQLQESWLELVRRHPSLRAEFDVCEGAKSFKDYSLKV 175 Query: 319 LKAAVPPEIPVLDIRHLDEQARLRWISERFEASLNEKLDITRWPLHSLSVIQTADLEYEL 378 PEI V DIRH+ QA+ + I++ E LN DI +PLH VIQ D EYEL Sbjct: 176 FSNPTLPEIEVQDIRHMSAQAKSQRINQIIEEILNNSFDIFVYPLHRFMVIQINDTEYEL 235 Query: 379 ILDINHMISDGLGNQQILRELLEIYGAESHNKAARLRPALPAGEYNRIVSEINAWNAPEE 438 IL NH++SDGLGNQQILRE+LEIY A+ + +L +L G+YN+++SEIN WN PEE Sbjct: 236 ILANNHLVSDGLGNQQILREILEIYAAKIQGVSVKLSESLSLGDYNKVISEINNWNDPEE 295 Query: 439 MEALDRYLQQQGRGAYFFNPXXXXXXXXXXXXXXXVIHSRKYWVGEEITARLIASTKTWR 498 + LD Y Q G+ Y FNP + ++KYW+GE IT L+ +K WR Sbjct: 296 NKNLDSYSQVCGKAKYSFNPFGSGNSDNEFAQ----VKTKKYWIGENITRLLMDKSKAWR 351 Query: 499 TSLFILLVSAYLKTIRQQGEERNRIILNLPTGGRLYPHTDASEVLSAFAQNLALSFTCGD 558 SLF L+VSA+LK+I Q E+ +IILNLPTGG++YP+ DA+ ++ FAQN+++SF + Sbjct: 352 VSLFTLMVSAHLKSITQLDEDGEQIILNLPTGGKVYPNIDATGLIGCFAQNMSVSFNSKE 411 Query: 559 ANEEWESLINRTHEEFTNQLSSGIDRAQTYRAAQYAKDTIHLQNGVMPEAVASMIRSTLK 618 A+E+W +L+ R +E +++SSGIDRAQTY AA+ AKD L++G M + A+ +RS+LK Sbjct: 412 ADEDWVTLVMRVDKEIKDKISSGIDRAQTYIAAKMAKDEDMLEDGKMAKTTAAFVRSSLK 471 Query: 619 SNLYLSFVGNTSIHTRYGDYEVYDYEAYTGTNPGTIDCLAELFQGRLMITANYDSSFFDD 678 SNLYLSFVG+T I YG+ ++ DYEAYT TN G ID + ELFQ ++ I++NYDS F + Sbjct: 472 SNLYLSFVGDTHIKEEYGNLKIVDYEAYTSTNSGAIDNIIELFQNQIFISSNYDSLHFHE 531 Query: 679 DYIGEHMDRFMDNLSQLAGMGPVGKPVLAGEDT----EGPHSAEIRERLYGIVRDISGTA 734 D I + +F+DNL LA + ED E + L I +I T Sbjct: 532 DDINLLIRKFIDNLYFLANYK------MENEDKVLRLEVSEDKMLLGELQKIAEEICCTT 585 Query: 735 LDEEALFKDMEAELGMDSLQRIRLITRLGKVFGHADKGALLECRTLNEIITHISHVNNAI 794 + EE + KD+E + G+DSLQ IR+I RL K+ DK +L CRTL+E+ + N ++ Sbjct: 586 ICEEDVHKDLETDFGIDSLQCIRIIRRLCKLHEGVDKNSLFGCRTLSEMALLVEK-NQSL 644 Query: 795 EPADRDSAAEIPYLHISRQCKATPDAVAILDGTREVTYRELDEQSNRLAHYLISQGVRSQ 854 +IPY I +QC+ATPDA+AI+ +TY+ELD SNR+A+YL SQGV+ Sbjct: 645 TGNYSGEEEQIPYRQIVKQCRATPDAIAIMYKDENITYKELDHISNRIANYLKSQGVKRG 704 Query: 855 SLVGILTFPGRLMLTGILGILKAGAAYVPLDPMYPADRIEYIAEHAQLSILLTEQSLQKQ 914 SLVGI+ FPG +ML G++GI+KAGAAYVP+DP YP +R++YI ++ + ILLTE L+ Sbjct: 705 SLVGIMVFPGPIMLFGMMGIMKAGAAYVPVDPSYPTERVQYILNNSDIEILLTEHGLKTS 764 Query: 915 TDPIVQKSPSIRKVVYLDEGYEVHG--HFEQTGTEVWQSCPAGDLRVDSAPHDLMVVLYT 972 + ++++ I+ ++YLD G + +++Q E W + G+ V ++P DLM VLYT Sbjct: 765 LEQLIKEDSVIKALMYLDYGTFLDSIYNYKQILKEQWMAANDGEPEVINSPDDLMTVLYT 824 Query: 973 SGSTGKPKGVMLNHRGYMNRLEWHQQTFCLQLGERVAQKTSCCFDISVWELLWPLMYGGT 1032 SGSTG PKGVML HRGYMNRL+WHQ TF L+ GERVAQKTSCCFDISVWEL WPLMYGG Sbjct: 825 SGSTGNPKGVMLGHRGYMNRLKWHQDTFKLKPGERVAQKTSCCFDISVWELFWPLMYGGI 884 Query: 1033 VCPVRQEIVKNPWSLARWMTDTGINVMHFVPSLFGEFVDSLEDESYTFPALRWLIFSGEG 1092 VCP +E VKNPWSL +W+ DT IN+MHFVPSLFGEFV++LED+ Y+F LRWLIFSGE Sbjct: 885 VCPASKETVKNPWSLGKWLIDTKINIMHFVPSLFGEFVNALEDDDYSFKDLRWLIFSGEA 944 Query: 1093 LPLRPVQKWMDRYGNKTKLANLYGPTEASIDVTYHIISGRPGSAGEMSIPIGKPIPGVYI 1152 LP+ +QKW+D++G LANLYGPTEASIDVT HII RPG GE SIPIGKPI V+I Sbjct: 945 LPMATIQKWIDKHGLSIGLANLYGPTEASIDVTCHIIDKRPGINGENSIPIGKPIDNVFI 1004 Query: 1153 KNLDEHMREVPXXXXXXXXXXXXQLAKGYLYNPEKTREAFHPNPFPEIPGEFIYRTGDLT 1212 KNLDE M+E+P QL+ GY+ N +KT EAF PNPF ++PG+++YRTGDLT Sbjct: 1005 KNLDEDMKELPDGEMGELWIGGIQLSSGYMNNKQKTEEAFKPNPFKDVPGDYLYRTGDLT 1064 Query: 1213 VKRADGSYEYHGRTDNQVKLRGFRVELGEIEAVLGSHDHVAEAAVIVTQPAPGQQLLLAC 1272 +R DGSYEYHGR DNQVK+RGFRVELGEIEAVLG+H V E AVI GQ+ L A Sbjct: 1065 SRRQDGSYEYHGRKDNQVKIRGFRVELGEIEAVLGTHPCVNETAVIAVDYIQGQKQLFAW 1124 Query: 1273 LAGKQVPDQEIKNFAVRKLPYYMIPHRVEWLPRLPKNPNGKLDRKALSVMFSGTGQAPQT 1332 ++G +V D E+K +KLPYYM+PHR EW+ LPK PNGKLDRK L+ Sbjct: 1125 VSGNKVDDSELKRCITKKLPYYMVPHRFEWVTVLPKTPNGKLDRKVLN------------ 1172 Query: 1333 PQASEMQIPPAAEREPLSAGDLLPLAPAQSWLMNYFDDPYCWAGYTRFLYKQPLDFQQFK 1392 + S+ ++ + L + +PL+PAQ+WLMNYFD PY W GYTRFLYKQPLD+ F Sbjct: 1173 -ELSQRKLKGNVVEDALISE--IPLSPAQNWLMNYFDYPYQWTGYTRFLYKQPLDYNLFN 1229 Query: 1393 QAVMMLNRRHDALRSILERKDNGFEQRFLQGELGGNV--DFYDGSHMEEAERNEEIGAIL 1450 +A+ +L HD LRS+L K ++Q+FL LG NV DFYDGSHME ER++E+ ++ Sbjct: 1230 KALSILTDNHDVLRSVLVNKGEKWQQKFL--PLGQNVEADFYDGSHMERKERDKEVKNLI 1287 Query: 1451 TEAIQGFRVDQWPLWRIIVVQVSEAVYEIAAVGHHLISDVVTNQLLLQEVWQIYASLSPG 1510 + I +VD+WPLW+++VV+V+ ++Y+I+ +GHHLISDV+TNQLL +++W+IY L Sbjct: 1288 DKIILDLKVDKWPLWKVVVVRVNSSLYDISVIGHHLISDVITNQLLFKDIWKIYRQLIL- 1346 Query: 1511 ARHISLPDAKPFADFVRAVQEKKRIHGKEYAGYWSTHFPPESVC-RLPADFIKGPNDEQS 1569 I L +K + DF+ V E+K+ G E+ YW FP E ++P DF G N EQS Sbjct: 1347 TEDIKLEKSKSYRDFILRVNEEKKNKGLEFVDYWKKQFPSEFYSFKIPEDFNLGSNTEQS 1406 Query: 1570 AATQRFTFDREQTSLLLTRAKKHFNSNVYPILLAPLYKELSVFFGQPEVVVSHRVHGREL 1629 A+++ F D+ +T LLT AKK F ++VYPILLAPLYK L + + +VVSHR++GR+L Sbjct: 1407 ASSEMFILDKAKTQQLLTTAKKCFQTSVYPILLAPLYKMLQRLYNKSWIVVSHRMNGRDL 1466 Query: 1630 SGGQNFMQTPGNFAVNFPLGINVEKGSHWSNLIASIRKGLENVPLGGVSYDLVSENLPRY 1689 G F QT GNFA+N+PLG+ + W+ ++ I + VP+ GVSYDL+S+NLP Y Sbjct: 1467 -GNNIFFQTAGNFAINYPLGVTIGHNEDWNEIVNKITNAMNGVPMNGVSYDLISDNLPSY 1525 Query: 1690 MYPDVKLTPIRANYLGNRDAPRLPGLE-FSREGMDRRLSLPGQKRISVIEFFFSIEEGKL 1748 +YPD+ L IR+NYLGNRD P+ E FS++ +DRR S P QKRIS IEFF+SI G+L Sbjct: 1526 LYPDLNLASIRSNYLGNRDIPQYDTFEFFSKDDIDRRYSQPDQKRISSIEFFYSIVNGEL 1585 Query: 1749 TVEIEYSANLYAAATIQSLAEQYREQALELLESIQD------TPVLPP------APRKGL 1796 +EIEYS N+Y+ +TI+ L +Y +E++ I + L P + ++G Sbjct: 1586 NLEIEYSKNMYSESTIKHLGSKYMRAFMEMISYINNKKNPKYNSTLKPLSLIRGSKKEGF 1645 Query: 1797 LANKVAVITXXXXXXXXXXALSMAGEGADIVLVSRSGQQLRETADEIRRLGXXXXXXXXX 1856 L+NK ++T A+ MA EGA+I ++SR+ +L ETA EI+ +G Sbjct: 1646 LSNKSVIVTGGGRGIGKTIAIEMAKEGAEIAIISRTAGELEETAAEIKGIGSKVMTITTD 1705 Query: 1857 XXXXXXXNKAVEQIIGSFGRIDILVNGAGITGMAAMADMSPGVWESIIQVNLLGTYHFCY 1916 AV++I+ FG+ID+LVN AGIT MA D+ W+ I++VNL GTY+ CY Sbjct: 1706 ISSYNDICDAVKKIVSEFGKIDVLVNNAGITKMAPFTDIKEEEWKRIVEVNLFGTYNLCY 1765 Query: 1917 AVIPYLXXXXXXXXXXXXSDSSFIGYPMMSAYAASKHGVLGLTRALSEELKNSNIQVNAV 1976 IP+ SDSSFIGYP+MSAY+ASKHG++GLT++L+EE K SNIQVNA+ Sbjct: 1766 LTIPHFVKQKSGKIINLGSDSSFIGYPLMSAYSASKHGIIGLTKSLAEEFKASNIQVNAI 1825 Query: 1977 CPALVDTDMAPAAFKGRAIPPSGVADSVVFLASPRADYITGEAVQVYGKQDMHWFGAQQM 2036 CPA+VDT+MAP AFK A+ P VAD V+FL+S ++DYITGEA++++GKQDM+WFG+ + Sbjct: 1826 CPAMVDTNMAPGAFKKNAMSPKKVADLVLFLSSNKSDYITGEAIKIFGKQDMYWFGSHHI 1885 Query: 2037 QMLQAVQRRQ 2046 L+A ++ Sbjct: 1886 PALRAALSKR 1895 Score = 116 bits (290), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 51/81 (62%), Positives = 69/81 (85%) Query: 19 VYQLVSNVTGHRIEDLNSDMYLEDDLGLDSIKMITLMNELIGLVPAEQMDDFTAAYPVTV 78 VY+L+SNVTGHRIEDL+ +M+LE DLG+DSIKM+TLMN+L+ LVP E +D+FT+ YP+ Sbjct: 15 VYELISNVTGHRIEDLDCEMFLEGDLGIDSIKMVTLMNQLMKLVPTEGLDEFTSMYPIAR 74 Query: 79 LMGLQTVGELVQIFEEWEHAR 99 LM LQT+GE+V IFEE+ + + Sbjct: 75 LMSLQTIGEIVLIFEEFYNGK 95 >Q3M5Z7.1 Q3M5Z7_ANAVT Amino acid adenylation EC=5.1.1.11 Length = 1643 Score = 1402 bits (3630), Expect = 0.0, Method: Compositional matrix adjust. Identities = 723/1656 (43%), Positives = 1026/1656 (61%), Gaps = 45/1656 (2%) Query: 137 EQLKIEVCRLISGITGHKSEDLHTDMDLERDLGLDSIKMITLMSEMVSLLPADSSGGHSE 196 + L++ + L++ ITGH +EDL DM LE +LGLDSIKM+ L++ +V+L+P + E Sbjct: 4 KSLELPIFSLVAKITGHDAEDLERDMFLEGNLGLDSIKMMELLNGLVALIPQEIQPKFME 63 Query: 197 SNLVTSLMSMHTVGDIVEM---LAVRNGGNSGTLAVAGDVNTIEAEIPENEPEFLEILHS 253 + + +LM + T+GD+V++ + NS + A +N + + E +EIL Sbjct: 64 TLPLQNLMQLQTLGDVVQIADNCLISPIDNSDSSPSASIINQ-----EQQKTEKVEILSG 118 Query: 254 QYLFLITYLSVANLTITSGVRVRGRLDADNLRKSWGELIRRHPILRAVFITEPANASLKG 313 QY L+ + V ++++ S +R+RG D +SW +L+ RHP+LR+ FI P K Sbjct: 119 QYFHLLGHWVVNSISLFSTLRLRGDFDTKVAWQSWKDLLNRHPMLRSRFIIPPDTTRFKD 178 Query: 314 YRLQLLKAAVPPEIPVLDIRHLDEQARLRWISERFEASLNEKLDITRWPLHSLSVIQTAD 373 Y + +++ PP+IPV DIRHL +A+ + I++ LN + +T WPLH V + D Sbjct: 179 YEMVVMENPTPPDIPVTDIRHLHSEAQEQLINDELHRCLNYEWQMTEWPLHRFFVFRLED 238 Query: 374 LEYELILDINHMISDGLGNQQILRELLEIYGAESHNKAARLRPALPAGEYNRIVSEINAW 433 Y+L+L H+ISD LG ILRE +EIY A + L+P +Y+ +V INAW Sbjct: 239 SVYQLVLANEHLISDALGCHVILREFMEIYRAHVCGEQPNLQPPTTVQDYSELVQSINAW 298 Query: 434 NAPEEMEALDRYLQQQGRGAYFFNPXXXXXXXXXXXXXXXVIHSRKYWVGEEITARLIAS 493 PEE +AL Y+ ++G+ +Y +NP H+R++ +G+ IT +LIA Sbjct: 299 QDPEEDKALVEYVNRRGKDSYLWNPTGNTITSLCPK-----FHNRRFSLGKAITGQLIAQ 353 Query: 494 TKTWRTSLFILLVSAYLKTIRQQGEERNR-IILNLPTGGRLYPHTDASEVLSAFAQNLAL 552 T+ WR L LLV A+++ + + + +N I++ +PT GR+YP DAS+V+ +FAQNL++ Sbjct: 354 TREWRLPLNSLLVGAFVRAVAKFEQSKNEPIMVQVPTSGRVYPGIDASDVVGSFAQNLSI 413 Query: 553 SFTCGDANEEWESLINRTHEEFTNQLSSGIDRAQTYRAAQYAKDTIHLQNGVMPEAVASM 612 S NE+W+ L+NR H+E L +G DRAQT + A +D I L++G +PE + M Sbjct: 414 SLDLPTPNEDWQRLLNRVHQEIQQGLVNGYDRAQTRQMAIAFRDNIVLEDGKIPERMLPM 473 Query: 613 IRSTLKSNLYLSFVGNTSIHTRYGDYEVYDYEAYTGTNPGTIDCLAELFQGRLMITANYD 672 R LKSNLY F G T+I +YG +V DY A GTID L E+F L + A+YD Sbjct: 474 YRRILKSNLYCPFTGQTNIKNKYGPIDVIDYRAGGINAAGTIDILQEIFDDSLHLFASYD 533 Query: 673 SSFFDDDYIGEHMDRFMDNLSQLAGMGPVGKPVLAGEDTEGPHSAEIRERLYGIVRDISG 732 S+FF + I E M ++ + +LA + + L + I + L I +I Sbjct: 534 SNFFPESVIDELMQEYITQIQELASLK-ISSEQLTQPLPKTQTDVNIAQLLQDIATEICH 592 Query: 733 TALDEEALFKDMEAELGMDSLQRIRLITRLGKVFGHADKGALLECRTLNEIITHISH--- 789 + + + + KD+EAELGMDSL+ IR++TRL K G ++ ALL CR+L E+ + Sbjct: 593 SQITDNDMAKDLEAELGMDSLELIRIVTRLEKRLGKVNRQALLSCRSLQEMAVLLGKKQS 652 Query: 790 -VNNAIEPADRDSAAEIPYLHISRQCKATPDAVAILDGTREVTYRELDEQSNRLAHYLIS 848 + EIPY I Q K TP+AVA+ DG ++TY EL+ SN++A+YL + Sbjct: 653 SSLQQQSVVNNQQPQEIPYWEIIEQAKRTPNAVAVTDGETQITYAELNRLSNQVANYLQA 712 Query: 849 QGVRSQSLVGILTFPGRLMLTGILGILKAGAAYVPLDPMYPADRIEYIAEHAQLSILLTE 908 QGV+ VGI+T G LM GILGILKAG YVPLDP+YP +RI+YI EHAQ+ ILLTE Sbjct: 713 QGVKPGVFVGIMTRRGPLMFVGILGILKAGGTYVPLDPIYPHERIKYILEHAQIGILLTE 772 Query: 909 QSLQKQTDPIVQKSPSIRKVVYLDEG-YEVHGHFEQTGTEVWQSCPAGDLRVDSAPHDLM 967 L + + + ++ +++LDEG +E + Q + W C + P DLM Sbjct: 773 NRLTNKLAECLTEQLPLKTLMFLDEGVFEQGKAWTQLNKKTWARCSDIAPANVNTPDDLM 832 Query: 968 VVLYTSGSTGKPKGVMLNHRGYMNRLEWHQQTFCLQLGERVAQKTSCCFDISVWELLWPL 1027 VLYTSGSTGKPKGVMLNHRGYMNRL W Q F L+ G+RVAQKTSCCFDISVWE+ WPL Sbjct: 833 TVLYTSGSTGKPKGVMLNHRGYMNRLVWMQNAFQLRYGDRVAQKTSCCFDISVWEIFWPL 892 Query: 1028 MYGGTVCPVRQEIVKNPWSLARWMTDTGINVMHFVPSLFGEFVDSLEDESYTFPALRWLI 1087 M G TV V E VKNPW LA+W+ D INVMHFVPSLFGEF +LE ES+TFP LRWL+ Sbjct: 893 MVGATVYSVETETVKNPWLLAQWIQDNQINVMHFVPSLFGEFCHALESESWTFPDLRWLV 952 Query: 1088 FSGEGLPLRPVQKWMDRYGNKTKLANLYGPTEASIDVTYHIISGRPGSAGEMSIPIGKPI 1147 FSGE LP+ VQ+W+D+YG LANLYGPTEASIDVT HII RPG E+ IPIGK I Sbjct: 953 FSGEALPVPFVQRWIDKYGMSVGLANLYGPTEASIDVTAHIIRQRPGEQ-EICIPIGKAI 1011 Query: 1148 PGVYIKNLDEHMREVPXXXXXXXXXXXXQLAKGYLYNPEKTREAFHPNPFPEIPGEFIYR 1207 VYI LDE M+ + QLAKGYL +P++T +AF NPF +PGE++Y+ Sbjct: 1012 DNVYILILDEQMQPLAPGKMGELWIGGVQLAKGYLKDPQRTADAFRLNPFSHVPGEYLYK 1071 Query: 1208 TGDLTVKRADGSYEYHGRTDNQVKLRGFRVELGEIEAVLGSHDHVAEAAVIVTQPAPGQQ 1267 TGDL V+ DGS+EYHGR D+Q+K+RGFRVELGEIE+VL SH ++EAAV+ GQ+ Sbjct: 1072 TGDLAVELPDGSFEYHGRIDHQIKIRGFRVELGEIESVLNSHPVISEAAVLAVDYENGQK 1131 Query: 1268 LLLACLAGKQVPDQEIKNFAVRKLPYYMIPHRVEWLPRLPKNPNGKLDRKALSVMFSGTG 1327 L+ACLAG QV +Q+IK F ++LP YMIPHR EWL LPK NGKLDRKA+ Sbjct: 1132 RLIACLAGSQVDNQQIKEFLAQRLPDYMIPHRWEWLASLPKTHNGKLDRKAI-------- 1183 Query: 1328 QAPQTPQASEMQIPPAAEREPLSAGDLLPLAPAQSWLMNYFDDPYCWAGYTRFLYKQPLD 1387 + + +P + + LPL PAQ WL+ YF+ PY W GYTRFL+ QPLD Sbjct: 1184 ------------LAAITQEKPTVSQEYLPLGPAQRWLVKYFEAPYQWNGYTRFLFHQPLD 1231 Query: 1388 FQQFKQAVMMLNRRHDALRSILERKDNGFEQRFLQGELGGNVDFYDGSHMEEAERNEEIG 1447 + F QA+ ++ H ALR++ ++D + Q+ + E + +FYDGS++ A+R+ EI Sbjct: 1232 PEIFNQALNIVLEAHPALRTVFVQRDQQWWQQLISPEQKLSAEFYDGSYLTSAQRDSEIH 1291 Query: 1448 AILTEAIQGFRVDQWPLWRIIVVQVSEAVYEIAAVGHHLISDVVTNQLLLQEVWQIYASL 1507 + E Q F++DQWPL ++I ++V+E+ Y+I+ VGHH+I D+++ ++ ++W Y+ L Sbjct: 1292 NRIQEIAQQFQIDQWPLMKVIAIKVNESCYDISLVGHHIIGDLLSTGVIFNQLWLTYSEL 1351 Query: 1508 SPGARHIS--LPDAKPFADFVRAV-QEKKRIHGKEYAGYWSTHFPP-ESVCRLPADFIKG 1563 IS LP + D+VRA+ Q +++ + + YW + FP E ++P D+ KG Sbjct: 1352 LGNRTQISQPLPATPSYIDYVRALMQAEQQGALRSHVDYWKSQFPSQEYTFQVPFDYQKG 1411 Query: 1564 PNDEQSAATQRFTFDREQTSLLLTRAKKHFNSNVYPILLAPLYKELSVFFGQPEVVVSHR 1623 N E SAA+++FT + +++LL AK+++ NVY +LL+ LY+ ++ + GQ VVVSHR Sbjct: 1412 ANLEASAASEKFTLSKNSSNILLREAKQYYKCNVYTLLLSTLYQLMAEWSGQHWVVVSHR 1471 Query: 1624 VHGRELSGGQNFMQTPGNFAVNFPLGINVEKGSHWSNLIASIRKGLENVPLGGVSYDLVS 1683 HGR L F+ + GNFA+NFP+G+N+E+ W I+ +P+ G+++D +S Sbjct: 1472 SHGRNLDSKHTFLNSVGNFAMNFPVGVNLERSIRWEQTTKEIQAKFNELPMNGITFDWIS 1531 Query: 1684 ENLPRYMYPDVKLTPIRANYLGNRDAPRLPGLEFSREGMDRRLSLPGQKRISVIEFFFSI 1743 E LP Y+YPD LTP+RANYLGNR AP EF E D RLS P QKR +++EFFFSI Sbjct: 1532 EQLPHYVYPDNNLTPVRANYLGNRTAPSSELFEFIEEDRDSRLSSPDQKRTALLEFFFSI 1591 Query: 1744 EEGKLTVEIEYSANLYAAATIQSLAEQYREQALELL 1779 +G + +EIEYS N + ATI+ L ++Y E ++L Sbjct: 1592 TDGTVHLEIEYSRNFHLPATIRRLGDRYLELMAQML 1627 Score = 79.3 bits (194), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 37/73 (50%), Positives = 51/73 (69%) Query: 19 VYQLVSNVTGHRIEDLNSDMYLEDDLGLDSIKMITLMNELIGLVPAEQMDDFTAAYPVTV 78 ++ LV+ +TGH EDL DM+LE +LGLDSIKM+ L+N L+ L+P E F P+ Sbjct: 10 IFSLVAKITGHDAEDLERDMFLEGNLGLDSIKMMELLNGLVALIPQEIQPKFMETLPLQN 69 Query: 79 LMGLQTVGELVQI 91 LM LQT+G++VQI Sbjct: 70 LMQLQTLGDVVQI 82 >B0JJG2.1 B0JJG2_MICAN Amino acid adenylation Length = 977 Score = 952 bits (2462), Expect = 0.0, Method: Compositional matrix adjust. Identities = 477/988 (48%), Positives = 647/988 (65%), Gaps = 27/988 (2%) Query: 802 AAEIPYLHISRQCKATPDAVAILDGTREVTYRELDEQSNRLAHYLISQGVRSQSLVGILT 861 + EIPY I +Q + TPDA+A+LD T +TY++LD SN++A YL +QGV + VGI+T Sbjct: 4 SPEIPYYKIIKQAQLTPDAIAVLDETCPLTYQQLDHLSNQVAAYLQTQGVNPNTRVGIMT 63 Query: 862 FPGRLMLTGILGILKAGAAYVPLDPMYPADRIEYIAEHAQLSILLTEQSLQKQTDPIVQK 921 M+ GILGILKAG YVPLDP YP +R+ YI +HA + ILLTE + +Q V + Sbjct: 64 ERNPGMIIGILGILKAGGCYVPLDPDYPVERLRYILDHATIEILLTEHQVSEQLISCVTE 123 Query: 922 SPSIRKVVYLDEGYEVH--GHFEQTGTEVWQSCPAGDLRVDSAPHDLMVVLYTSGSTGKP 979 ++ V++LDEG ++ Q T +WQ + + + P DLMV+LYTSGSTG+P Sbjct: 124 PLPLQTVLFLDEGERLNKINDLTQITTSIWQKHSKESINLCNRPEDLMVILYTSGSTGRP 183 Query: 980 KGVMLNHRGYMNRLEWHQQTFCLQLGERVAQKTSCCFDISVWELLWPLMYGGTVCPVRQE 1039 KGVMLNHRGYMNRLEW Q+TF L+ G+RVAQ+TS CFDISVWE+ W LM G T+CPV++E Sbjct: 184 KGVMLNHRGYMNRLEWMQKTFSLKTGDRVAQRTSFCFDISVWEIFWTLMEGATICPVKRE 243 Query: 1040 IVKNPWSLARWMTDTGINVMHFVPSLFGEFVDSLEDESYTFPALRWLIFSGEGLPLRPVQ 1099 +V NPW A W+ T INVMHFVPSLFGEF+ ++E+ES+TFP LRWLIFSGE LP+ +Q Sbjct: 244 VVLNPWEFAAWIKKTKINVMHFVPSLFGEFISAIENESWTFPDLRWLIFSGEALPMSFIQ 303 Query: 1100 KWMDRYGNKTKLANLYGPTEASIDVTYHIISGRPGSAGEMSIPIGKPIPGVYIKNLDEHM 1159 KW+D YG KT LANLYGPTEASIDVTYHII+ RP IPIGK I VY+K LD+ M Sbjct: 304 KWLDCYGLKTGLANLYGPTEASIDVTYHIITERPDERTSSQIPIGKAIDNVYLKVLDDQM 363 Query: 1160 REVPXXXXXXXXXXXXQLAKGYLYNPEKTREAFHPNPFPEIPGEFIYRTGDLTVKRADGS 1219 + V QLA GYL +PEKT +AF NPF ++ G++IYRTGDL + DG+ Sbjct: 364 QPVKQGEMGELWLGGVQLALGYLKDPEKTAKAFCSNPFSDVSGDYIYRTGDLVKELPDGT 423 Query: 1220 YEYHGRTDNQVKLRGFRVELGEIEAVLGSHDHVAEAAVIVTQPAPGQQLLLACLAGKQVP 1279 EYHGR DN VK+RGFR+ELGEIE++L +H +V EAAV+ GQ+ L+ACL+G ++ Sbjct: 424 LEYHGRIDNMVKIRGFRIELGEIESILTTHPNVREAAVLAIDYGEGQKRLIACLSGDKIK 483 Query: 1280 DQEIKNFAVRKLPYYMIPHRVEWLPRLPKNPNGKLDRKALSVMFSGTGQAPQTPQASEMQ 1339 ++ +K +KLP+YMIP R W P+L KN NGKLDRKAL+ Sbjct: 484 NRVLKAHLEQKLPHYMIPQRFAWFPQLAKNHNGKLDRKALAAELLPA------------- 530 Query: 1340 IPPAAEREPLSAGDLLPLAPAQSWLMNYFDDPYCWAGYTRFLYKQPLDFQQFKQAVMMLN 1399 A L+PL PAQSWL+NYF+ PY W GYTRFLY Q L+ F QA +L Sbjct: 531 ---PAAPAAPPTPSLIPLGPAQSWLVNYFEPPYQWLGYTRFLYHQSLNLDIFNQAANLLV 587 Query: 1400 RRHDALRSILERKDNGFEQRFLQGELGGNVDFYDGSHMEEAERNEEIGAILTEAIQGFRV 1459 +RH+A R++ + ++Q + +++DGSH+ EAERN +I A +++ + ++ Sbjct: 588 QRHEAFRTVCLQNQGKWQQYLINDPQPILAEYWDGSHLTEAERNAKIKAQMSDLAKTIQI 647 Query: 1460 DQWPLWRIIVVQVSEAVYEIAAVGHHLISDVVTNQLLLQEVWQIYASLSPGARHISLPDA 1519 D+WPL +VV+VS Y+I V HH+I+D+++ +L +E+W Y L G+ + P+ Sbjct: 648 DRWPLTATLVVKVSPYCYDITMVAHHIIADMLSATILFKELWSAYHQLLVGSDP-TFPNP 706 Query: 1520 KP--FADFVRAVQ-EKKRIHGKEYAGYWSTHFP-PESVCRLPADFIKGPNDEQSAATQRF 1575 P + DFV+ ++ E+K+ E+ YW FP ES +P D +KGPN E SA + RF Sbjct: 707 NPQSYLDFVQVLRDEEKKGTMNEHLNYWKEQFPDAESRFEVPVDHVKGPNIEASAESARF 766 Query: 1576 TFDREQTSLLLTRAKKHFNSNVYPILLAPLYKELSVFFGQPEVVVSHRVHGRELSGGQNF 1635 + QT LL++ K ++ SN YPILLAPLY+ L + + +VV+SHR HGR+L GQ+F Sbjct: 767 VLSKAQTKQLLSQGKAYYQSNFYPILLAPLYRLLGDWSQRKQVVISHRSHGRDLGEGQSF 826 Query: 1636 MQTPGNFAVNFPLGINVEKGSHWSNLIASIRKGLENVPLGGVSYDLVSENLPRYMYPDVK 1695 M++ GN+AVNFP+GIN+ + W I++I + E++P+ GV+YD + E+LP Y+YPD Sbjct: 827 MESMGNYAVNFPIGINLSTSTTWQKTISTINEQFESLPMNGVTYDWIGESLPEYLYPDSN 886 Query: 1696 LTPIRANYLGNRDAPRLPGLEFSREGMDRRLSLPGQKRISVIEFFFSIEEGKLTVEIEYS 1755 LTP+RANYLGNR P EF D RLS QKR ++IEFFF I +G+L + IEYS Sbjct: 887 LTPVRANYLGNRSVPLSDLFEFVYGERDCRLSPLDQKRTTLIEFFFLIIDGQLEIRIEYS 946 Query: 1756 ANLYAAATIQSLAEQYREQALELLESIQ 1783 N + TIQ + + Y L LLE ++ Sbjct: 947 RNFHLPTTIQKIGQDY----LILLEELE 970 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 11,887,356,026 Number of extensions: 504120822 Number of successful extensions: 1376165 Number of sequences better than 1.0e-05: 30899 Number of HSP's gapped: 1313695 Number of HSP's successfully gapped: 37108 Length of query: 2047 Length of database: 3,060,696,203 Length adjustment: 151 Effective length of query: 1896 Effective length of database: 1,638,122,938 Effective search space: 3105881090448 Effective search space used: 3105881090448 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 139 (58.2 bits)