BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0263.0012.p (1166 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A7GTF8.1 A7GTF8_BACCN Beta-ketoacyl synthase 1164 0.0 B9E1U5.1 B9E1U5_CLOK1 Putative uncharacterized protein 1079 0.0 A5N8D8.1 A5N8D8_CLOK5 Predicted polyketide synthase 1079 0.0 Q3M5Z6.1 Q3M5Z6_ANAVT Short-chain dehydrogenase/reductase SDR EC... 954 0.0 A7Z474.1 A7Z474_BACA2 MlnE 458 e-126 >A7GTF8.1 A7GTF8_BACCN Beta-ketoacyl synthase Length = 3099 Score = 1164 bits (3012), Expect = 0.0, Method: Compositional matrix adjust. Identities = 588/1190 (49%), Positives = 764/1190 (64%), Gaps = 70/1190 (5%) Query: 1 VITGRKPVPANPE---------------LLLELEKLGAQVMYAAVDVTSRAQMEELLARI 45 V+TGR+ +P+ E ++ +LE GA+V Y AVDVT+ +M+E++ + Sbjct: 1883 VLTGREQLPSREEWKKGNLSSKVVSKINVIQDLENQGAKVEYFAVDVTNEQKMKEMIQAV 1942 Query: 46 HDVYGPLHGVIHAAGQMEYAPHKLLTRSQDEIEQVLAPKWQGTIIADLVTRQEPLRFFAA 105 +YG +HGV+HAAG + ++ KLL++ ++I+QV++ K QGTIIAD+VTRQEPL+FF Sbjct: 1943 KQLYGSIHGVVHAAGTIHHSAGKLLSKDLNDIQQVMSSKVQGTIIADMVTRQEPLKFFVT 2002 Query: 106 LSSVSASRKAWASGLGDYAAANAFLNGYCIYRAGDNAPGRSLSINYSLWKDTGAGTDFGR 165 LSS+SAS+K WA+ LGDYAAANAFLNGY YR APGRSLSINYSLW D G FG Sbjct: 2003 LSSISASKKIWAANLGDYAAANAFLNGYSQYRKNTGAPGRSLSINYSLWADKGLSEMFGD 2062 Query: 166 LVELALKGQGLQPLAHEAAAAVFLRALSSPGSDIVHVLD----LVEPKAHKEAFALPPSR 221 L LA+K Q L PL+ E F L G +VH+LD V ++ L PS Sbjct: 2063 LSALAVKAQKLNPLSSEGGTQAFFEVLQYEGKSVVHILDRQEDCVANNVAEKVVVLSPS- 2121 Query: 222 QEPARLAEQKFIHRSAREIRDIVYQAIGEELRISVRHLETGMNFTELGLDSVGATRVVAD 281 EPA +++A+EI++IVYQ I E+ LE NF EL +DS+ AT+V+A+ Sbjct: 2122 NEPAHPVR----YKTAKEIKEIVYQVIAAEINCDAESLEVTKNFLELSIDSLKATKVIAE 2177 Query: 282 IGGKLGTELYPTLIFEYQTPEALASHIAEQLTEDSXXXXXXXXXXXXXXXXXXXXXRQDI 341 IG +L TELYPTL+FEYQTPEALA +I + + +DI Sbjct: 2178 IGKQLNTELYPTLLFEYQTPEALAEYIEKTYAVNRQEKVEVRQKEKIGKDEESV---KDI 2234 Query: 342 AIIGMGLRIPGANSLEEYWELLYSGRSAIREVDPGRWSDDKHVNEDAGVFHTSYTGKGGF 401 AIIGM +RIPGAN+LEEYW++L G I+EV RW + H + D G+ H +Y+ GGF Sbjct: 2235 AIIGMSVRIPGANNLEEYWKILREGECMIQEVPEDRWRKEYHYSSDQGILHKTYSKHGGF 2294 Query: 402 IDAPYDFDPLFFGMSPKEAESADPQQRIFLQICWEALQQAGYGGKYRTRKIGVFAGCEQN 461 I+ PYDFDPLFFGMSPKEAE+ DPQQRIF+Q+ WEALQQAGYGGK+RT +IGVF GCEQN Sbjct: 2295 IERPYDFDPLFFGMSPKEAEATDPQQRIFMQVAWEALQQAGYGGKHRTNQIGVFVGCEQN 2354 Query: 462 TYMEHFANYRSYMLIKERLLDSPAFLGMLPAERQEILARISGVLEPARLVADVVAGNGLN 521 TYMEHF YR YM++K+ L F + ++RQ +L ++ +LEP +LVAD +AGNGLN Sbjct: 2355 TYMEHFIGYRYYMMMKDVLEKENTFAHLPLSDRQNLLKQMVRILEPGQLVADAIAGNGLN 2414 Query: 522 EVAARVSHCLNLSGPSLIVNSACSSSLVAIHMACESLRTGQSEMALAGGVNLNLSPTPFV 581 EVAARVSHCLNL+GPS+IVN+ACSSSLVA+H AC+S+R G++ MA+AGGVNLNLSPTPFV Sbjct: 2415 EVAARVSHCLNLTGPSMIVNTACSSSLVALHHACQSIRQGETNMAIAGGVNLNLSPTPFV 2474 Query: 582 SLSRVTALSPTGECYPFDQRANGMVLGEGAGAVLLKPLHAALRDGDHIHAVIKGSAVNND 641 SLSRVTALS G CYPFD RANGMVL EGAGAVLLK L A+ DGDHI AVIKGSA+NND Sbjct: 2475 SLSRVTALSSNGNCYPFDARANGMVLSEGAGAVLLKSLEQAMEDGDHIFAVIKGSAINND 2534 Query: 642 GRSQGITAPRPQGQAEVIREAFVRTGIHPETVSYIETHGTATPLGDPIEIEGMTRAFSSF 701 GRSQGITAPRPQGQAEVIR A++ +HPETVSYIETHGTATPLGDPIE+EGMTRAF +F Sbjct: 2535 GRSQGITAPRPQGQAEVIRSAYLNANVHPETVSYIETHGTATPLGDPIEVEGMTRAFRTF 2594 Query: 702 TDKKQFCGIGSVKSSVGHMLSAAGVTSLIKVVLSLKHQILPHTVNYEQPNPNIDFEHSPF 761 TDK+ FCGIGSVKSS+GHMLSAAG+ SL+KV L++KH+++PHTVNY+ PNPN+DF+HSPF Sbjct: 2595 TDKEGFCGIGSVKSSIGHMLSAAGIVSLVKVALAMKHKVIPHTVNYDTPNPNLDFQHSPF 2654 Query: 762 YVVDKHPRRW-EAAGDAPLRASVNAFGFGGTNAHVILEQAP----------PEMVVVPDX 810 YVV K P+ W + + PLRA VNAFGFGGTNAHVILE+AP PEM Sbjct: 2655 YVVAKQPQIWGDEKQNHPLRAGVNAFGFGGTNAHVILEEAPILQRKVNHSVPEM------ 2708 Query: 811 XXXXXXXXXXXXXXXXXXXQVAGRLRAYLADNQELSAAAVCRAMNRSQKELPVKAAAVVT 870 VA RL+ ++ N +L VC +MN SQKEL K A V+ Sbjct: 2709 --KRPSLLLLTGRTEKVIQNVAMRLKEHIKQNPDLCVPEVCYSMNSSQKELSCKVATVIK 2766 Query: 871 SREHLAGILSAVADGGSLPEILRGRANPNRTTPVQWVLDGGKALSGQELDAVSARFPGFG 930 S+EHL +L A+ G E+++GR+NPN+ ++ DG L + ++ F F Sbjct: 2767 SKEHLYSVLEAIEMGRERSEVIKGRSNPNKRMTTHFLFDGTLCLDKAHIKQLNDTFSIFH 2826 Query: 931 LAYREVMEA-------AGGASGQIECLASQFALGKLLLDAGLRPSAILAEGAGIPAALML 983 AY++ ++ + QI+ + Q+A+GKLLL +G++P + + EG GI Sbjct: 2827 AAYKKCLDVFETEENENSTSYRQIQSFSCQYAIGKLLLHSGIQPKSFVCEGIGILVGAAC 2886 Query: 984 TGRITLRQAVLFIQDGREPAGDS-SPLPEGLVKCAVVIPSGTVDQPFMDGLWPQIAESMV 1042 TG IT+ A+ FI+ + + + K ++ P G + + D L M Sbjct: 2887 TGIITVEAAIQFIKGNKNLTSEILQNRNDTEYKYTIITPMGIIHKEHTDILKSLCMTDMQ 2946 Query: 1043 NSLELTDYEHSLEAGDTLLYCGS-----QHRRNSLPLEGIRGVHTLCLPLEHDPVEHLLR 1097 ++ D ++ D ++ CG Q R S+ + + D V LL Sbjct: 2947 YTITTKDIAEYVDKNDVVIQCGISKSDLQGRLISMDIGKVS-----------DSVHELLL 2995 Query: 1098 AMAELYVLGVPFDPAGLSVPCGRTLPLPTYPFEYAAYKASYEDEILQPQA 1147 MA+LY LGV ++ +PLPTYPFE YK ++EDE + +A Sbjct: 2996 CMAKLYTLGVNYNSVAFFEGNENRIPLPTYPFENKMYKVTFEDENIYKEA 3045 Score = 412 bits (1059), Expect = e-112, Method: Compositional matrix adjust. Identities = 268/827 (32%), Positives = 411/827 (49%), Gaps = 52/827 (6%) Query: 235 RSAREIRDIVYQAIGEELRISVRHLETGMNFTELGLDSVGATRVVADIGGKLGTELYPTL 294 + A +IR+I E L I + H +F LG S+ A +++ + +L L + Sbjct: 613 KYAEKIREI----WSEVLEIPLEHTPYNESFLSLGGTSIKAIQILGYLEDELSLTLSHDI 668 Query: 295 IFEYQTPEALASHIAEQLTEDSXXXXXXXXXXXXXXXXXXXXXRQDIAIIGMGLRIPGAN 354 + +T + +I + + + DIA+I + R P A+ Sbjct: 669 LINCRTVNEMDEYIVKVVQGNEGIESGKVKVSSRKMSEEY---EGDIAVIALSCRFPDAS 725 Query: 355 SLEEYWELLYSGRSAIREVDPGRWSDDKHVNEDAGVFHTSYTGKGGFIDAPYDFDPLFFG 414 + E +WE L G+ +I+E+ RWS + N+ F +Y KG FI PY FD F Sbjct: 726 TPEAFWENLVQGKCSIKEIPSDRWSVKDYYNQIPQ-FGKTYCRKGAFIQNPYAFDASLFN 784 Query: 415 MSPKEAESADPQQRIFLQICWEALQQAGYGGKYRT-RKIGVFAGCEQNTYMEHFANYRSY 473 +S +EA DPQQR+ L++ +E +++AGY + K+G+F G N+Y E Y Sbjct: 785 ISEEEAAIMDPQQRMILELTYELIERAGYTTQMVDGEKVGLFIGAGMNSYYE----YHLS 840 Query: 474 MLIKERLLDSPAFLGMLPAERQEILARISGVLEPARLVADVVAGNGLNEVAARVSHCLNL 533 L ++ L +F + +++ I+ +++ N LN +AAR S N Sbjct: 841 TLNRQNLQTFDSFKALPKVQQEAIMNEWKKKFGIMAAHPNILVDNILNMIAARTSQEFNF 900 Query: 534 SGPSLIVNSACSSSLVAIHMACESLRTGQSEMALAGGVNLNLSPTPFVSLSRVTALSPTG 593 GPS++V++ACSSSLV +HMA ESL+ G+ E+A+AGG+NL L+P P++ S ALS +G Sbjct: 901 KGPSMVVDTACSSSLVTLHMAYESLKRGECEVAIAGGINLLLTPAPYIFFSHAGALSSSG 960 Query: 594 ECYPFDQRANGMVLGEGAGAVLLKPLHAALRDGDHIHAVIKGSAVNNDGRSQGITAPRPQ 653 FD++A+G V GEGAG V+LK L A DGD + A IK S +NNDGRS G+ AP P Sbjct: 961 RSMVFDEQADGFVPGEGAGLVMLKTLKKAKADGDKVLATIKASTINNDGRSIGVMAPNPD 1020 Query: 654 GQAEVIREAFVRTGIHPETVSYIETHGTATPLGDPIEIEGMTRAFSSFTDKKQFCGIGSV 713 GQ EVI +V I P+T+ Y+E HGT T +GDP E+ + AF + +Q IGSV Sbjct: 1021 GQREVIESLYVENEISPQTIQYVEAHGTGTRVGDPSEVRAIDTAFRKWNVGQQSIAIGSV 1080 Query: 714 KSSVGHMLSAAGVTSLIKVVLSLKHQILPHTVNYEQPNPNIDFEHSPFYVVDKHPRRWEA 773 K+++GH+L AAG+ S IKV++SL ++ +P +N PNP I E +PFY++D+ P+ W Sbjct: 1081 KANIGHLLGAAGIGSFIKVIMSLLYRKMPPNINIFTPNPMIKLEQTPFYLLDE-PKEWSK 1139 Query: 774 AGDAPLRASVNAFGFGGTNAHVILEQAP-PEMVVVPDXXXXXXXXXXXXXXXXXXXXQVA 832 P RA++N+FGFGGTN H+I+E+A + V V Q Sbjct: 1140 EKGVPRRAAINSFGFGGTNCHLIVEEASETKEVKVNQAIELPKHVLCLSAHSESALQQKV 1199 Query: 833 GRLRAYLADNQELSAAAVCRAMNRSQKELPVKAAAVVTSREHLAGILSAVADGGSLPEIL 892 L A L D+ E S VC N ++ L + + + +S + L L + ++ + Sbjct: 1200 TNLIACLEDSYEYSLGDVCYTENVTRTPLKHRYSVIASSIDDLIEKLKNSSLDNTMVQ-- 1257 Query: 893 RGRANPNRTTPVQWVLDG-GKALSG--QELDAVSARFPGF-----------------GLA 932 A+P V + G G +G ++L + RF + L Sbjct: 1258 ---ASPK----VALMFTGQGSQYAGMARQLYKLVPRFKKYVDDCSEAFYPILNQSIVDLL 1310 Query: 933 YREVMEA--AGGASGQIECLASQFALGKLLLDAGLRPSAILAEGAGIPAALMLTGRITLR 990 Y E E+ A Q +ALGKLLLD G++P+ +L G A L+ ITL+ Sbjct: 1311 YVEANESLLAQTHITQPVVFTIDYALGKLLLDLGVKPACMLGHSVGEWVAACLSEMITLQ 1370 Query: 991 QAVLFIQDGREPAGDSSPLPEGLVKCAVVIPSGTVD---QPFMDGLW 1034 A + E + + A+ T++ +PF D LW Sbjct: 1371 DAARLVAIRGELMNE---IQTTGAMTAIFSSIATIEPLLEPFKDSLW 1414 >B9E1U5.1 B9E1U5_CLOK1 Putative uncharacterized protein Length = 3072 Score = 1079 bits (2790), Expect = 0.0, Method: Compositional matrix adjust. Identities = 556/1172 (47%), Positives = 745/1172 (63%), Gaps = 56/1172 (4%) Query: 1 VITGRKPVP----------------ANPELLLELEKLGAQVMYAAVDVTSRAQMEELLAR 44 V+TGR+ +P EL+L LEKLGA V Y AVDVT +ME L+ + Sbjct: 1880 VLTGREKLPLIEEWNTQISNNAKCAKKIELILSLEKLGANVTYEAVDVTKINEMEVLMEK 1939 Query: 45 IHDVYGPLHGVIHAAGQMEYAPHKLLTRSQDEIEQVLAPKWQGTIIADLVTRQEPLRFFA 104 ++++YG + GVIHAAG +++ KLL +S D + V+ PK QG +I D VTR+EPL+FF Sbjct: 1940 VNNIYGSIQGVIHAAGTWDFSSFKLLDKSIDTVNSVIEPKVQGAVITDYVTRKEPLKFFV 1999 Query: 105 ALSSVSASRKAWASGLGDYAAANAFLNGYCIYRAGDNAPGRSLSINYSLWKDTGAGTDFG 164 LSSVS+S+K W++GLGDYAAAN+FL+ Y +RA +NAPG+++++NYSLW TG G + G Sbjct: 2000 MLSSVSSSKKIWSAGLGDYAAANSFLSTYSFHRASENAPGKTIALNYSLWAKTGMGANLG 2059 Query: 165 RLVELALKGQGLQPLAHEAAAAVFLRALSSPGSDIVHVLDLVEPKAHKEAFALPPSRQEP 224 + +A+K QGL PL E A +R LS ++H+LD +E K+ P Sbjct: 2060 NMASMAVKVQGLNPLPAEKAVEALMRVLSDGSQRVIHILDKLEITQEKK----------P 2109 Query: 225 ARLAEQKFIHRSAREIRDIVYQAIGEELRISVRHLETGMNFTELGLDSVGATRVVADIGG 284 + + ++ IR+ V + I ++L++ L+ G NF ELGLDS+GA +V+ +G Sbjct: 2110 LSIKVNTLDFKKSQNIRETVCKIIADQLQVHQEELDIGQNFLELGLDSLGAVKVMEKLGH 2169 Query: 285 KLGTELYPTLIFEYQTPEALASHIAEQLTEDSXXXXXXXXXXXXXXXXXXXXXRQDIAII 344 LG ELYPTLIFEYQTP++LA +I + DS + DIAII Sbjct: 2170 NLGIELYPTLIFEYQTPDSLAQYIEKVYFGDSDGVTAQEIDISERNTSSMEKIK-DIAII 2228 Query: 345 GMGLRIPGANSLEEYWELLYSGRSAIREVDPGRWSDDKHVNEDAGVFHTSYTGKGGFIDA 404 G +RIPGAN+L+EYW +L SG+ IREV RWS + + D +TSY+ GGFID Sbjct: 2229 GASVRIPGANTLDEYWSILESGKCMIREVPSERWSLKDYFSTDVNSLYTSYSKCGGFIDK 2288 Query: 405 PYDFDPLFFGMSPKEAESADPQQRIFLQICWEALQQAGYGGKYRTRKIGVFAGCEQNTYM 464 PY+FDP+FFG+SP EA DPQQRIFL+I WEALQQAGYGG+Y + IGVF GCEQNTY Sbjct: 2289 PYEFDPMFFGLSPSEAAVTDPQQRIFLEIAWEALQQAGYGGRYGSNNIGVFVGCEQNTYA 2348 Query: 465 EHFANYRSYMLIKERLLDSPAFLGMLPAERQEILARISGVLEPARLVADVVAGNGLNEVA 524 EHFANY YM +K L + F + E+ +I+ I VL+PA +V D VAGN LNEVA Sbjct: 2349 EHFANYGIYMKLKNYLSSNHTFNNIGHVEQDKIMNSIFNVLKPAEMVPDFVAGNSLNEVA 2408 Query: 525 ARVSHCLNLSGPSLIVNSACSSSLVAIHMACESLRTGQSEMALAGGVNLNLSPTPFVSLS 584 ARVSHCLN +GPSL +NSACSSSL A+H+ACES+RTGQSEMA+ GGVNLNLSPTPFV LS Sbjct: 2409 ARVSHCLNFTGPSLTINSACSSSLAALHLACESIRTGQSEMAIVGGVNLNLSPTPFVGLS 2468 Query: 585 RVTALSPTGECYPFDQRANGMVLGEGAGAVLLKPLHAALRDGDHIHAVIKGSAVNNDGRS 644 RVTALS TG CYPFD RA+GMV+ EGA AVLLKPL A+RD D+I AVIKGSA+NNDG S Sbjct: 2469 RVTALSKTGVCYPFDSRADGMVISEGASAVLLKPLENAMRDRDNILAVIKGSAMNNDGHS 2528 Query: 645 QGITAPRPQGQAEVIREAFVRTGIHPETVSYIETHGTATPLGDPIEIEGMTRAFSSFTDK 704 QG+TAPRPQGQA+ IR+A++ I+PET+SYIETHGT TPLGDPIEI+GM AF SFT + Sbjct: 2529 QGLTAPRPQGQADAIRKAYLEANINPETISYIETHGTGTPLGDPIEIQGMNHAFRSFTSE 2588 Query: 705 KQFCGIGSVKSSVGHMLSAAGVTSLIKVVLSLKHQILPHTVNYEQ--PNPNIDFEHSPFY 762 K FC IGSVKSS+GHMLSA+GVTSLIKVVL+LK++ +PHTVNY++ NPNIDF +SPFY Sbjct: 2589 KAFCAIGSVKSSIGHMLSASGVTSLIKVVLALKNKKIPHTVNYDKSRSNPNIDFANSPFY 2648 Query: 763 VVDKHPRRWEAAGDAPLRASVNAFGFGGTNAHVILEQAPPEMVVVPDXXXXXXXXXXXXX 822 VV P W++ PLRA VNAFGFGGTN HV+LE+AP + Sbjct: 2649 VVSGEPMEWKSNNITPLRAGVNAFGFGGTNVHVVLEKAPD---MREYEEERPPYLLQLTG 2705 Query: 823 XXXXXXXQVAGRLRAYLADNQELSAAAVCRAMNRSQKELPVKAAAVVTSREHLAGILSAV 882 ++A L+ ++ ++ LSAA++C +N +QKEL K AAVV SR HL +L+++ Sbjct: 2706 RNENVVKRIAANLKNHIKQHENLSAASICFTVNSAQKELITKTAAVVKSRAHLLEVLTSL 2765 Query: 883 ADGGSLPEILRGRANPNRTTPVQWVLDGGKALSGQELDAVSARFPGFGLAYREVM----E 938 +G S+ + +GR++PNR +LD + + +RF F AYRE M E Sbjct: 2766 ENGSSIEGVYKGRSHPNRENQAYLMLDDNIKIFEDCKHDLCSRFAAFDTAYRECMDIYKE 2825 Query: 939 AAGGASGQIE---CLASQFALGKLLLDAGLRPSAILAEGAGIPAALMLTGRITLRQA--- 992 G S +IE A Q+ALG LL D L I+A+G GI A +LTG I L QA Sbjct: 2826 LKNGYSEEIEPIDSFAVQYALGVLLNDFDLNICGIIAQGTGILTAAVLTGLINLEQALGQ 2885 Query: 993 ---VLFIQDGREPAGDSSPLPEGLVKCAVVIPSGTVDQPFMDGLWPQIAESMVNSLELTD 1049 + I+DG + + + + ++ PSG +++ F+D I ++ +++ D Sbjct: 2886 LIHISVIEDGNYSKSNENAV---YLNYPILTPSGAIEE-FLD-----IPIKVIENIKSLD 2936 Query: 1050 YEHSLEAGDTLLYCGSQHRRNSLPLEGIRGVHTLCLPLEHDPVEHLLRAMAELYVLGVPF 1109 + ++Y G + + R + + + + + VE ++ A+LYVLG + Sbjct: 2937 --GFVNKDQVVIYPGKVDKIKNKEFYDDRLFNWVEMNINENAVESIITVFAKLYVLGARY 2994 Query: 1110 DPAGLSVPCGRTLPLPTYPFEYAAYKASYEDE 1141 +P S + + LPTYPFE YK S++++ Sbjct: 2995 NPNKFSTGKEKKVALPTYPFENETYKISFQEK 3026 Score = 404 bits (1039), Expect = e-110, Method: Compositional matrix adjust. Identities = 247/676 (36%), Positives = 360/676 (53%), Gaps = 36/676 (5%) Query: 340 DIAIIGMGLRIPGANSLEEYWELLYSGRSAIREVDPGRWSDDKHVNEDAGVFHTSYTGKG 399 DIA+I M R P A++ EE+W + +G+ +I E+ RW DK+ + + T+ G Sbjct: 706 DIAVIEMACRFPDASTPEEFWNNIVNGKCSIDEIPADRWDIDKYYSPNVDAIKTN-CRTG 764 Query: 400 GFIDAPYDFDPLFFGMSPKEAESADPQQRIFLQICWEALQQAGY-GGKYRTRKIGVFAGC 458 FID P+DFD FF +S +EA DPQQRI L++ +E L++AGY K + +G+F G Sbjct: 765 AFIDKPFDFDAEFFNISDEEAAVMDPQQRIMLELVFEILERAGYCKKKIGGKNLGLFIGA 824 Query: 459 EQNTYMEHFANYRSYMLIKERLLDSPAFLGMLPAERQEILARISGVLEPARLVADVVAGN 518 N+Y E+ N L L +F + E++ IL L +++ N Sbjct: 825 GTNSYYEYHLN----TLNMSNLKSFDSFNSLTKEEQESILEEWKNKLGITHFHPNLLVDN 880 Query: 519 GLNEVAARVSHCLNLSGPSLIVNSACSSSLVAIHMACESLRTGQSEMALAGGVNLNLSPT 578 LN VAAR S NL GPS++V++ACSSS+V IH+AC+SL G+ E ALAGG+NL L+PT Sbjct: 881 ILNMVAARTSQEFNLKGPSMVVDTACSSSIVTIHLACQSLLRGECEFALAGGINLLLTPT 940 Query: 579 PFVSLSRVTALSPTGECYPFDQRANGMVLGEGAGAVLLKPLHAALRDGDHIHAVIKGSAV 638 P++ S ALS +G FD +A+G V GEGAG VLLKPL AL+D D++ AVIK SA+ Sbjct: 941 PYIYFSSAGALSTSGLSRVFDSQADGFVPGEGAGLVLLKPLKKALKDEDNVLAVIKASAI 1000 Query: 639 NNDGRSQGITAPRPQGQAEVIREAFVRTGIHPETVSYIETHGTATPLGDPIEIEGMTRAF 698 NNDG S G+ AP P GQ EVI +V G +P+ + Y+E HGT T +GD E+ + RAF Sbjct: 1001 NNDGHSIGVMAPNPDGQREVIESLYVNNGFNPKDIQYVEAHGTGTKIGDLSEVRALDRAF 1060 Query: 699 SSFTDKKQFCGIGSVKSSVGHMLSAAGVTSLIKVVLSLKHQILPHTVNYEQPNPNIDFEH 758 ++ + IGSVKS++GH+LS AG+ S IKVVL+L ++I+P VN + NP+I F+ Sbjct: 1061 KRWSPEANSIAIGSVKSNIGHLLSGAGIASFIKVVLALNNKIMPPNVNLNELNPSIKFDR 1120 Query: 759 SPFYVVDKHPRRWEAAGDAPLRASVNAFGFGGTNAHVILEQAPPEMVVVPDXXXX-XXXX 817 +PFY + K + W + + RAS+N+FGFGGTN H+++E+ P + Sbjct: 1121 TPFYTIFK-AKEWSVSPNIARRASINSFGFGGTNCHMVIEETPELTKTKSEKIYEHSKHV 1179 Query: 818 XXXXXXXXXXXXQVAGRLRAYLADNQELSAAAVCRAMNRSQKELPVKAAAVVTSREHLAG 877 Q L +L N E S +C N ++ L + + V S E L Sbjct: 1180 LCLSANTKESLNQKIKNLVEHLKTNNESSLGDICYTENVTRTLLKYRCSVVADSCEDLMS 1239 Query: 878 ILSAVA----DGGSLPEI---LRGRANPNRTTPVQWVLDGGKALSG-----QELDAVSAR 925 L V DG + P+I G+ + Q+V G + +D S Sbjct: 1240 KLQEVKLDNIDGKAFPKIALMFTGQGS-------QYVGMGKQLYENLPIFRTYIDECSEV 1292 Query: 926 FPGF------GLAYREVMEAAGGASGQIE---CLASQFALGKLLLDAGLRPSAILAEGAG 976 F + L Y + + A I +A GK +D G++P +L G Sbjct: 1293 FYPYLNEKITDLIYSDKADEILLARTNITQPVVFTIDYAFGKFFIDLGVKPDYVLGHSIG 1352 Query: 977 IPAALMLTGRITLRQA 992 +A L+G ++L+ A Sbjct: 1353 EWSAACLSGIVSLQDA 1368 >A5N8D8.1 A5N8D8_CLOK5 Predicted polyketide synthase Length = 3072 Score = 1079 bits (2790), Expect = 0.0, Method: Compositional matrix adjust. Identities = 556/1172 (47%), Positives = 745/1172 (63%), Gaps = 56/1172 (4%) Query: 1 VITGRKPVP----------------ANPELLLELEKLGAQVMYAAVDVTSRAQMEELLAR 44 V+TGR+ +P EL+L LEKLGA V Y AVDVT +ME L+ + Sbjct: 1880 VLTGREKLPLIEEWNTQISNNAKCAKKIELILSLEKLGANVTYEAVDVTKINEMEVLMEK 1939 Query: 45 IHDVYGPLHGVIHAAGQMEYAPHKLLTRSQDEIEQVLAPKWQGTIIADLVTRQEPLRFFA 104 ++++YG + GVIHAAG +++ KLL +S D + V+ PK QG +I D VTR+EPL+FF Sbjct: 1940 VNNIYGSIQGVIHAAGTWDFSSFKLLDKSIDTVNSVIEPKVQGAVITDYVTRKEPLKFFV 1999 Query: 105 ALSSVSASRKAWASGLGDYAAANAFLNGYCIYRAGDNAPGRSLSINYSLWKDTGAGTDFG 164 LSSVS+S+K W++GLGDYAAAN+FL+ Y +RA +NAPG+++++NYSLW TG G + G Sbjct: 2000 MLSSVSSSKKIWSAGLGDYAAANSFLSTYSFHRASENAPGKTIALNYSLWAKTGMGANLG 2059 Query: 165 RLVELALKGQGLQPLAHEAAAAVFLRALSSPGSDIVHVLDLVEPKAHKEAFALPPSRQEP 224 + +A+K QGL PL E A +R LS ++H+LD +E K+ P Sbjct: 2060 NMASMAVKVQGLNPLPAEKAVEALMRVLSDGSQRVIHILDKLEITQEKK----------P 2109 Query: 225 ARLAEQKFIHRSAREIRDIVYQAIGEELRISVRHLETGMNFTELGLDSVGATRVVADIGG 284 + + ++ IR+ V + I ++L++ L+ G NF ELGLDS+GA +V+ +G Sbjct: 2110 LSIKVNTLDFKKSQNIRETVCKIIADQLQVHQEELDIGQNFLELGLDSLGAVKVMEKLGH 2169 Query: 285 KLGTELYPTLIFEYQTPEALASHIAEQLTEDSXXXXXXXXXXXXXXXXXXXXXRQDIAII 344 LG ELYPTLIFEYQTP++LA +I + DS + DIAII Sbjct: 2170 NLGIELYPTLIFEYQTPDSLAQYIEKVYFGDSDGVTAQEIDISERNTSSMEKIK-DIAII 2228 Query: 345 GMGLRIPGANSLEEYWELLYSGRSAIREVDPGRWSDDKHVNEDAGVFHTSYTGKGGFIDA 404 G +RIPGAN+L+EYW +L SG+ IREV RWS + + D +TSY+ GGFID Sbjct: 2229 GASVRIPGANTLDEYWSILESGKCMIREVPSERWSLKDYFSTDVNSLYTSYSKCGGFIDK 2288 Query: 405 PYDFDPLFFGMSPKEAESADPQQRIFLQICWEALQQAGYGGKYRTRKIGVFAGCEQNTYM 464 PY+FDP+FFG+SP EA DPQQRIFL+I WEALQQAGYGG+Y + IGVF GCEQNTY Sbjct: 2289 PYEFDPMFFGLSPSEAAVTDPQQRIFLEIAWEALQQAGYGGRYGSNNIGVFVGCEQNTYA 2348 Query: 465 EHFANYRSYMLIKERLLDSPAFLGMLPAERQEILARISGVLEPARLVADVVAGNGLNEVA 524 EHFANY YM +K L + F + E+ +I+ I VL+PA +V D VAGN LNEVA Sbjct: 2349 EHFANYGIYMKLKNYLSSNHTFNNIGHVEQDKIMNSIFNVLKPAEMVPDFVAGNSLNEVA 2408 Query: 525 ARVSHCLNLSGPSLIVNSACSSSLVAIHMACESLRTGQSEMALAGGVNLNLSPTPFVSLS 584 ARVSHCLN +GPSL +NSACSSSL A+H+ACES+RTGQSEMA+ GGVNLNLSPTPFV LS Sbjct: 2409 ARVSHCLNFTGPSLTINSACSSSLAALHLACESIRTGQSEMAIVGGVNLNLSPTPFVGLS 2468 Query: 585 RVTALSPTGECYPFDQRANGMVLGEGAGAVLLKPLHAALRDGDHIHAVIKGSAVNNDGRS 644 RVTALS TG CYPFD RA+GMV+ EGA AVLLKPL A+RD D+I AVIKGSA+NNDG S Sbjct: 2469 RVTALSKTGVCYPFDSRADGMVISEGASAVLLKPLENAMRDRDNILAVIKGSAMNNDGHS 2528 Query: 645 QGITAPRPQGQAEVIREAFVRTGIHPETVSYIETHGTATPLGDPIEIEGMTRAFSSFTDK 704 QG+TAPRPQGQA+ IR+A++ I+PET+SYIETHGT TPLGDPIEI+GM AF SFT + Sbjct: 2529 QGLTAPRPQGQADAIRKAYLEANINPETISYIETHGTGTPLGDPIEIQGMNHAFRSFTSE 2588 Query: 705 KQFCGIGSVKSSVGHMLSAAGVTSLIKVVLSLKHQILPHTVNYEQ--PNPNIDFEHSPFY 762 K FC IGSVKSS+GHMLSA+GVTSLIKVVL+LK++ +PHTVNY++ NPNIDF +SPFY Sbjct: 2589 KAFCAIGSVKSSIGHMLSASGVTSLIKVVLALKNKKIPHTVNYDKSRSNPNIDFANSPFY 2648 Query: 763 VVDKHPRRWEAAGDAPLRASVNAFGFGGTNAHVILEQAPPEMVVVPDXXXXXXXXXXXXX 822 VV P W++ PLRA VNAFGFGGTN HV+LE+AP + Sbjct: 2649 VVSGEPMEWKSNNITPLRAGVNAFGFGGTNVHVVLEKAPD---MREYEEERPPYLLQLTG 2705 Query: 823 XXXXXXXQVAGRLRAYLADNQELSAAAVCRAMNRSQKELPVKAAAVVTSREHLAGILSAV 882 ++A L+ ++ ++ LSAA++C +N +QKEL K AAVV SR HL +L+++ Sbjct: 2706 RNENVVKRIAANLKNHIKQHENLSAASICFTVNSAQKELITKTAAVVKSRAHLLEVLTSL 2765 Query: 883 ADGGSLPEILRGRANPNRTTPVQWVLDGGKALSGQELDAVSARFPGFGLAYREVM----E 938 +G S+ + +GR++PNR +LD + + +RF F AYRE M E Sbjct: 2766 ENGSSIEGVYKGRSHPNRENQAYLMLDDNIKIFEDCKHDLCSRFAAFDTAYRECMDIYKE 2825 Query: 939 AAGGASGQIE---CLASQFALGKLLLDAGLRPSAILAEGAGIPAALMLTGRITLRQA--- 992 G S +IE A Q+ALG LL D L I+A+G GI A +LTG I L QA Sbjct: 2826 LKNGYSEEIEPIDSFAVQYALGVLLNDFDLNICGIIAQGTGILTAAVLTGLINLEQALGQ 2885 Query: 993 ---VLFIQDGREPAGDSSPLPEGLVKCAVVIPSGTVDQPFMDGLWPQIAESMVNSLELTD 1049 + I+DG + + + + ++ PSG +++ F+D I ++ +++ D Sbjct: 2886 LIHISVIEDGNYSKSNENAV---YLNYPILTPSGAIEE-FLD-----IPIKVIENIKSLD 2936 Query: 1050 YEHSLEAGDTLLYCGSQHRRNSLPLEGIRGVHTLCLPLEHDPVEHLLRAMAELYVLGVPF 1109 + ++Y G + + R + + + + + VE ++ A+LYVLG + Sbjct: 2937 --GFVNKDQVVIYPGKVDKIKNKEFYDDRLFNWVEMNINENAVESIITVFAKLYVLGARY 2994 Query: 1110 DPAGLSVPCGRTLPLPTYPFEYAAYKASYEDE 1141 +P S + + LPTYPFE YK S++++ Sbjct: 2995 NPNKFSTGKEKKVALPTYPFENETYKISFQEK 3026 Score = 404 bits (1039), Expect = e-110, Method: Compositional matrix adjust. Identities = 247/676 (36%), Positives = 360/676 (53%), Gaps = 36/676 (5%) Query: 340 DIAIIGMGLRIPGANSLEEYWELLYSGRSAIREVDPGRWSDDKHVNEDAGVFHTSYTGKG 399 DIA+I M R P A++ EE+W + +G+ +I E+ RW DK+ + + T+ G Sbjct: 706 DIAVIEMACRFPDASTPEEFWNNIVNGKCSIDEIPADRWDIDKYYSPNVDAIKTN-CRTG 764 Query: 400 GFIDAPYDFDPLFFGMSPKEAESADPQQRIFLQICWEALQQAGY-GGKYRTRKIGVFAGC 458 FID P+DFD FF +S +EA DPQQRI L++ +E L++AGY K + +G+F G Sbjct: 765 AFIDKPFDFDAEFFNISDEEAAVMDPQQRIMLELVFEILERAGYCKKKIGGKNLGLFIGA 824 Query: 459 EQNTYMEHFANYRSYMLIKERLLDSPAFLGMLPAERQEILARISGVLEPARLVADVVAGN 518 N+Y E+ N L L +F + E++ IL L +++ N Sbjct: 825 GTNSYYEYHLN----TLNMSNLKSFDSFNSLTKEEQESILEEWKNKLGITHFHPNLLVDN 880 Query: 519 GLNEVAARVSHCLNLSGPSLIVNSACSSSLVAIHMACESLRTGQSEMALAGGVNLNLSPT 578 LN VAAR S NL GPS++V++ACSSS+V IH+AC+SL G+ E ALAGG+NL L+PT Sbjct: 881 ILNMVAARTSQEFNLKGPSMVVDTACSSSIVTIHLACQSLLRGECEFALAGGINLLLTPT 940 Query: 579 PFVSLSRVTALSPTGECYPFDQRANGMVLGEGAGAVLLKPLHAALRDGDHIHAVIKGSAV 638 P++ S ALS +G FD +A+G V GEGAG VLLKPL AL+D D++ AVIK SA+ Sbjct: 941 PYIYFSSAGALSTSGLSRVFDSQADGFVPGEGAGLVLLKPLKKALKDEDNVLAVIKASAI 1000 Query: 639 NNDGRSQGITAPRPQGQAEVIREAFVRTGIHPETVSYIETHGTATPLGDPIEIEGMTRAF 698 NNDG S G+ AP P GQ EVI +V G +P+ + Y+E HGT T +GD E+ + RAF Sbjct: 1001 NNDGHSIGVMAPNPDGQREVIESLYVNNGFNPKDIQYVEAHGTGTKIGDLSEVRALDRAF 1060 Query: 699 SSFTDKKQFCGIGSVKSSVGHMLSAAGVTSLIKVVLSLKHQILPHTVNYEQPNPNIDFEH 758 ++ + IGSVKS++GH+LS AG+ S IKVVL+L ++I+P VN + NP+I F+ Sbjct: 1061 KRWSPEANSIAIGSVKSNIGHLLSGAGIASFIKVVLALNNKIMPPNVNLNELNPSIKFDR 1120 Query: 759 SPFYVVDKHPRRWEAAGDAPLRASVNAFGFGGTNAHVILEQAPPEMVVVPDXXXX-XXXX 817 +PFY + K + W + + RAS+N+FGFGGTN H+++E+ P + Sbjct: 1121 TPFYTIFK-AKEWSVSPNIARRASINSFGFGGTNCHMVIEETPELTKTKSEKIYEHSKHV 1179 Query: 818 XXXXXXXXXXXXQVAGRLRAYLADNQELSAAAVCRAMNRSQKELPVKAAAVVTSREHLAG 877 Q L +L N E S +C N ++ L + + V S E L Sbjct: 1180 LCLSANTKESLNQKIKNLVEHLKTNNESSLGDICYTENVTRTLLKYRCSVVADSCEDLMS 1239 Query: 878 ILSAVA----DGGSLPEI---LRGRANPNRTTPVQWVLDGGKALSG-----QELDAVSAR 925 L V DG + P+I G+ + Q+V G + +D S Sbjct: 1240 KLQEVKLDNIDGKAFPKIALMFTGQGS-------QYVGMGKQLYENLPIFRTYIDECSEV 1292 Query: 926 FPGF------GLAYREVMEAAGGASGQIE---CLASQFALGKLLLDAGLRPSAILAEGAG 976 F + L Y + + A I +A GK +D G++P +L G Sbjct: 1293 FYPYLNEKITDLIYSDKADEILLARTNITQPVVFTIDYAFGKFFIDLGVKPDYVLGHSIG 1352 Query: 977 IPAALMLTGRITLRQA 992 +A L+G ++L+ A Sbjct: 1353 EWSAACLSGIVSLQDA 1368 >Q3M5Z6.1 Q3M5Z6_ANAVT Short-chain dehydrogenase/reductase SDR EC=2.3.1.94 Length = 2551 Score = 954 bits (2466), Expect = 0.0, Method: Compositional matrix adjust. Identities = 530/1206 (43%), Positives = 715/1206 (59%), Gaps = 73/1206 (6%) Query: 1 VITGRKPVPANPEL---------------LLELEKLGAQVMYAAVDVTSRAQMEELLARI 45 V+TGR P+P E + +LE+LGA VMY AVDVT M++L+ I Sbjct: 1232 VLTGRHPLPPKQEWQSASHDASTQQRIQAIQQLEQLGATVMYQAVDVTDALGMKQLIESI 1291 Query: 46 HDVYGPLHGVIHAAGQMEYAPHKLLTRSQDEIEQVLAPKWQGTIIADLVTRQEPLRFFAA 105 +G L GVIHAAG ++++ KLL + + +VLAPK QGTII D VTR EPL++F Sbjct: 1292 KSRFGNLDGVIHAAGAVDHSTFKLLQKQPASVTKVLAPKVQGTIILDTVTRNEPLKYFVL 1351 Query: 106 LSSVSASRKAWASGLGDYAAANAFLNGYCIYRAGDNAPGRSLSINYSLWKDTGAGTDFGR 165 LSSVSAS+ W +G+GDYAAAN FL+ Y IYR GRSL++NYSLW D G G G Sbjct: 1352 LSSVSASKAEWGTGMGDYAAANTFLDSYAIYRTQHGGQGRSLALNYSLWSDRGMGALLGA 1411 Query: 166 LVELALKGQGLQPLAHEAAAAVFLRALSSPGSDIVHVLDLVEPKAHKEAFALPPSRQEPA 225 L ++ +GL PL E AA F++ALS S ++H++DL+ +A E + Q A Sbjct: 1412 STLLMVRSKGLNPLEPEPAANAFIQALSLDASPVIHIIDLIA-QATPEIAPKSSASQSQA 1470 Query: 226 RLAEQKFIHRSAREIRDIVYQAIGEELRISVRHLETGMNFTELGLDSVGATRVVADIGGK 285 + R +R +V + + + LRI +E F E+GLDSVG VV +G Sbjct: 1471 K----------PRNLRQLVREVLLQHLRIPEAQVEGHKTFQEMGLDSVGTVEVVQHLGTT 1520 Query: 286 LGTELYPTLIFEYQTPEALASHIAEQL----------------------TEDSXXXXXXX 323 LG EL+PTL+FEYQTP+ L ++ + S Sbjct: 1521 LGEELFPTLLFEYQTPDDLVDYLQSKYGYSVKTSTSAMDYAPPLVIAPEETSSPQTEKSA 1580 Query: 324 XXXXXXXXXXXXXXRQDIAIIGMGLRIPGANSLEEYWELLYSGRSAIREVDPGRWSDDKH 383 QDIAIIGM +IPGA++LE+YW+LL +GRS I++V RW + + Sbjct: 1581 PPNVAPQEKYQDVPEQDIAIIGMACKIPGADNLEQYWDLLNAGRSVIQDVPQDRWFNQHY 1640 Query: 384 VNEDAGVFHTSYTGKGGFIDAPYDFDPLFFGMSPKEAESADPQQRIFLQICWEALQQAGY 443 + +G F+++P+DFDP+FFG+SPKEA + DPQQR+FL++ +ALQQAGY Sbjct: 1641 FEAKGNSPQAKISKRGCFVNSPFDFDPMFFGISPKEATAMDPQQRLFLELSMQALQQAGY 1700 Query: 444 GGKYRTRKIGVFAGCEQNTYMEHFANYRSYMLIKERLLDSPAFLGMLPAE-RQEILARIS 502 GGKYR IGVF GC QNTY+EHF NY+ Y +++RL +S ++ LPAE RQ +L +S Sbjct: 1701 GGKYRPDNIGVFVGCGQNTYIEHFTNYQYYEELRQRLQES-SWFDHLPAEDRQHLLKTLS 1759 Query: 503 GVLEPARLVADVVAGNGLNEVAARVSHCLNLSGPSLIVNSACSSSLVAIHMACESLRTGQ 562 VL+P+ ++ + AGN +NE+AARVSHCLNL GPS+ V++ACSSSLVA+H+ACESLR+GQ Sbjct: 1760 QVLQPSEILPESAAGNEVNELAARVSHCLNLKGPSMAVSTACSSSLVALHIACESLRSGQ 1819 Query: 563 SEMALAGGVNLNLSPTPFVSLSRVTALSPTGECYPFDQRANGMVLGEGAGAVLLKPLHAA 622 + MA+ GGVNLNLSP+PF L + ALS +G CYPFD+RANG+VLGEGAG +++KPL A Sbjct: 1820 TGMAIVGGVNLNLSPSPFTFLRKAQALSLSGTCYPFDRRANGIVLGEGAGVLIIKPLKQA 1879 Query: 623 LRDGDHIHAVIKGSAVNNDGRSQGITAPRPQGQAEVIREAFVRTGIHPETVSYIETHGTA 682 L DGD IHAVIKGSAVNNDG SQGITAP P+GQAE IR+A+ G+ P T+SYIETHGT Sbjct: 1880 LADGDLIHAVIKGSAVNNDGHSQGITAPNPKGQAEAIRQAYNSCGVDPRTISYIETHGTG 1939 Query: 683 TPLGDPIEIEGMTRAFSSFTDKKQFCGIGSVKSSVGHMLSAAGVTSLIKVVLSLKHQILP 742 T LGDP+E+EGMT+AF SFTD+K FC IGSVKSS+GH+LSA+G+ SLIKVVL+++H +P Sbjct: 1940 TLLGDPVEVEGMTKAFRSFTDEKGFCTIGSVKSSIGHLLSASGIVSLIKVVLAMQHGKIP 1999 Query: 743 HTVNYEQPNPNIDFEHSPFYVVDKHPRRWEAAGDAPLRASVNAFGFGGTNAHVILEQAPP 802 TV +E+PNP+I+F +PF V K W G+ PLRA VN FGFGGTN HVILE++P Sbjct: 2000 QTVGFEEPNPHINFADTPFTVAGKS-IPWSPNGN-PLRAGVNGFGFGGTNCHVILEESPV 2057 Query: 803 EMVVVPDXXXXXXXXXXXXXXXXXXXXQVAGRLRAYLADNQELSAAAVCRAMNRSQKELP 862 + +VA +LR ++ + E ++ +C N +QKELP Sbjct: 2058 AANLQSQVTSSAPDLLCLTARNQQALQEVARQLRQHIIHHPEQESSQICFTQNNAQKELP 2117 Query: 863 VKAAAVVTSREHLAGILSAVADGGSLPEILRGRANPNRTTPVQWVLDGGKALSGQELDAV 922 KAA VV R+HL L A+ + +I GRANP RTTP +LDG A++ E++ + Sbjct: 2118 YKAALVVNDRQHLLNYLEAICSAQTPADIYTGRANPQRTTPFHLILDGTSAIAPAEIETL 2177 Query: 923 SARFPGFGLAYREVMEAAGGASGQIECLASQFALGKLLLDAGLRPSAILAEGAGIPAALM 982 RFP F +AY V S Q A Q+A G+LL+ L+P+++L E GI A Sbjct: 2178 GQRFPQFQVAYNSVRAGFHEMSEQAHIFAVQYAWGRLLMSLELQPTSLLVEKTGILAGAT 2237 Query: 983 LTGRITLRQAVLFIQDGREPAG----DSSPLPE--GLVKCAVVIPSGTV---DQPFMDGL 1033 L G +TL QA+ + G D S + C +V G D D L Sbjct: 2238 LRGMLTLEQAIALLLQIEGEKGLSVHDVSAKEQSASTWTCPLVTSQGIFSHADTISTDQL 2297 Query: 1034 WP--QIAESM---VNSLELTDYEHSLEAGDTLLYCGSQHRRNSLPLEGIRGVHTLCLPLE 1088 Q++E + V ++ L GD+ + + SL G+ + L Sbjct: 2298 LALVQVSEQLNVDVCQDVISKESVYLHLGDSF---ALKEQLASLDELGVW----IYLNKR 2350 Query: 1089 HDPVEHLLRAMAELYVLGVPFDPAGLSVPCGRTLPLPTYPFEYAAYKASYEDEILQPQAS 1148 VE +L ++A YV G+ F+ L R + LPTYPFE Y+ S D + QA+ Sbjct: 2351 QPVVERVLTSLARSYVAGIRFNSIPLFPQGLRRVLLPTYPFERKTYRVSLVDHTQENQAT 2410 Query: 1149 GTPYAD 1154 P A+ Sbjct: 2411 SIPAAE 2416 Score = 351 bits (901), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 212/566 (37%), Positives = 304/566 (53%), Gaps = 39/566 (6%) Query: 341 IAIIGMGLRIPG-ANSLEEYWELLYSGRSAIREVDPGRWSDDKHVNEDAGVFHTSYTGKG 399 IAIIGM R PG A+ E++WELL++G I EV RW D++ N + YT G Sbjct: 38 IAIIGMNCRFPGGADYPEKFWELLHNGVDTITEVPADRWDVDEYYNANPNTLGKIYTRYG 97 Query: 400 GFIDAPYDFDPLFFGMSPKEAESADPQQRIFLQICWEALQQAGYG-GKYRTRKIGVFAGC 458 GFI FDP FFG+SP EA S DPQ R+ L++ WEA++ AG + + GVF G Sbjct: 98 GFIKQVDQFDPHFFGLSPLEAASMDPQHRLLLEVGWEAIENAGQSPEELNGSQTGVFMGL 157 Query: 459 EQNTYMEHFANYRSYMLIKERLLDSPAFLGMLPAERQEILARISGVLEPARLVADVVAGN 518 +ME ++ + Y SG + R+ A GN Sbjct: 158 ----FMEDYSRFNLY----------------------------SG--DHHRIDAYSSLGN 183 Query: 519 GLNEVAARVSHCLNLSGPSLIVNSACSSSLVAIHMACESLRTGQSEMALAGGVNLNLSPT 578 + R+++ L L GP + +++ACSSSL+A+H+AC+SLR+G+ MALAGGVNL L+P Sbjct: 184 ARSIAIGRLAYVLGLQGPVMQLDTACSSSLLAVHLACQSLRSGECNMALAGGVNLILAPE 243 Query: 579 PFVSLSRVTALSPTGECYPFDQRANGMVLGEGAGAVLLKPLHAALRDGDHIHAVIKGSAV 638 + LSR+ AL+P G C FD +A+G V GEG G V+LK L A+ + D+I AV++GSAV Sbjct: 244 ASIGLSRMRALAPDGRCKTFDAKADGYVRGEGCGIVVLKRLSDAIANNDNILAVVRGSAV 303 Query: 639 NNDGRSQGITAPRPQGQAEVIREAFVRTGIHPETVSYIETHGTATPLGDPIEIEGMTRAF 698 N+DG S G+T P Q ++I +A + PE +SY+ETHGT T LGDPIE+ + Sbjct: 304 NHDGASSGLTVPNGLAQEKLINQALTNAKVAPEQISYVETHGTGTSLGDPIEVRALGSVL 363 Query: 699 SSFTDKKQFCGIGSVKSSVGHMLSAAGVTSLIKVVLSLKHQILPHTVNYEQPNPNIDFEH 758 +Q IGSVK+ +GH+ SAAGV SL+KVVL+L++ +P ++ +QP+P+I ++ Sbjct: 364 CQGRSPEQPLLIGSVKTQLGHLESAAGVASLMKVVLALQNAEIPPHLHLQQPSPHIPWDK 423 Query: 759 SPFYVVDKHPRRWEAAGDAPLRASVNAFGFGGTNAHVILEQAPPEMVVVPDXXXXXXXXX 818 V K P W A L A V++FG GTNAH+I+E+AP + +P Sbjct: 424 LAVAVPTK-PTPWPAVNGKRL-AGVSSFGMSGTNAHLIIEEAPELKLELPKTERPLHLLS 481 Query: 819 XXXXXXXXXXXQVAGRLRAYLADNQELSAAAVCRAMNRSQKELPVKAAAVVTSREHLAGI 878 +A R ++L + E S A +C N + + A V S L Sbjct: 482 LSAKTEAALLA-MASRYESFLTSHPETSLADICFTANTGRSHFEHRLAVVAASNADLREQ 540 Query: 879 LSAVADGGSLPEILRGRANPNRTTPV 904 L+A A + G+ R+ V Sbjct: 541 LTAFASQKQTSTSVSGQVQKKRSKVV 566 >A7Z474.1 A7Z474_BACA2 MlnE Length = 2334 Score = 458 bits (1179), Expect = e-126, Method: Compositional matrix adjust. Identities = 288/824 (34%), Positives = 428/824 (51%), Gaps = 74/824 (8%) Query: 1 VITGRKPVP-ANPELLLELEKLGAQVMYAAVDVTSRAQMEELLARIHDVYGPLHGVIHAA 59 ++TGR P + L LE LGA+ +Y D++ + + L+ I +G L+G++H+A Sbjct: 302 ILTGRSPASRETAQKLSALENLGAEALYVPADISKEKETDALIKYIKQTFGELNGILHSA 361 Query: 60 GQMEYAPHKLLTRSQDEIEQVLAPKWQGTIIADLVTRQEPLRFFAALSSVSASRKAWASG 119 G ++ A ++ ++++ IE+V+APK GT+ D +EPL FF SS+SA +G Sbjct: 362 GLVKDAF--IIKKTKESIEEVIAPKVFGTVWLDKAAEEEPLDFFVMFSSLSAVLP--NAG 417 Query: 120 LGDYAAANAFLNGYCIYRAGDNAPGRSLSINYSLWKDTGAGTDFGRLVELALKGQGLQPL 179 DYA AN ++G+ YR+ PG++LSIN+ LW G L AL+ GL+ L Sbjct: 418 QSDYAFANGCMDGFTQYRSMKGRPGKTLSINWPLWDAGNMTVGPGEL--QALRHAGLELL 475 Query: 180 AHEAAAAVFLRALSSPGSDIVHV------LDLVEPKAHKEAFALPPSRQEPARLAEQKFI 233 + +A A F ++S S + + + + HK+ +P + +L E+ Sbjct: 476 SAQAGLAAFQDSMSRSASQLAVISGDKDRISELLSTDHKKIETVPENNSNLPQLHEKDLK 535 Query: 234 HRSAREIRDIVYQAIGEELRISVRHLETGMNFTELGLDSVGATRVVADIGGKLGTELYPT 293 ++ R + +IV G E + F G+DS+ + + + G + T Sbjct: 536 KQTVRLLTEIV----GAETGRPADSILPEDTFDRYGIDSLTILGLNSRLEKYFG-RVSKT 590 Query: 294 LIFEYQTPEALASHIAEQLTEDSXXXXXXXXXXXXXXXXXXXXXR------------QDI 341 L FEY + E L+ + E + + +DI Sbjct: 591 LFFEYSSVEELSEYFLEHYQHELQKAFLPAAEQRIDHSAPAKREKLSVSRIPSAPSEEDI 650 Query: 342 AIIGMGLRIPGANSLEEYWELLYSGRSAIREVDPGRWSDDKHVNEDAGVFHTSYTGKGGF 401 AIIG+ R P A +E++WE + SG+ I E+ RW K+ + H S GGF Sbjct: 651 AIIGIAGRYPMAKDVEQFWENISSGKDCITEIPKERWDFRKYYHTGDNARHDSKW--GGF 708 Query: 402 IDAPYDFDPLFFGMSPKEAESADPQQRIFLQICWEALQQAGYGGKYRTR-KIGVFAGCEQ 460 I FDPLFF +SP++AE DPQ+R+FL+ W + AGY K R K GVF G Sbjct: 709 IKDADKFDPLFFSISPRDAELIDPQERLFLETAWHTFEDAGYTKKKLKRHKTGVFVG--- 765 Query: 461 NTYMEHFANYRSYMLIKERLLDSPAFLGMLPAERQEILARISGVLEPARLVADVVAGNGL 520 Y Y L D ERQ +L+ S Sbjct: 766 -------VTYSHYQLFAAGASDD--------EERQALLSSYSS----------------- 793 Query: 521 NEVAARVSHCLNLSGPSLIVNSACSSSLVAIHMACESLRTGQSEMALAGGVNLNLSPTPF 580 +A RVS+ +L GPSL +++ CSSSL A+H ACESL+ G+S +A+AGGVNL+L P + Sbjct: 794 --IANRVSYFFDLHGPSLAIDTMCSSSLSAVHFACESLKRGESTLAIAGGVNLSLHPDKY 851 Query: 581 VSLSRVTALSPTGECYPFDQRANGMVLGEGAGAVLLKPLHAALRDGDHIHAVIKGSAVNN 640 LS+ +S G C F +G V GEG GAVLLK L AA DGD I+ VIKG++VN+ Sbjct: 852 TLLSQNHFVSSDGRCRSFGAGGDGYVPGEGVGAVLLKSLSAAKADGDRIYGVIKGTSVNH 911 Query: 641 DGRSQGITAPRPQGQAEVIREAFVRTGIHPETVSYIETHGTATPLGDPIEIEGMTRAF-S 699 G++ G T P P QA VI E + GI +++SYIE HGT T LGDPIEI G+T+A S Sbjct: 912 GGKTNGYTVPNPGEQANVISETLDKAGIDADSISYIEAHGTGTSLGDPIEISGLTKALHS 971 Query: 700 SFTDKKQFCGIGSVKSSVGHMLSAAGVTSLIKVVLSLKHQILPHTVNYEQPNPNIDFEHS 759 S +D + C IGSVKS++GH+ +AAG+ S+ KV++ +K++ L +++ NPNIDFE + Sbjct: 972 SKSDYR--CAIGSVKSNIGHLEAAAGIASITKVLMQMKYKQLAPSLHSGNLNPNIDFEET 1029 Query: 760 PFYVVDKHPRRWEAAGDAPLRASVNAFGFGGTNAHVILEQAPPE 803 PFY V WE + R+ +++FG GG+NAH+I+E+ E Sbjct: 1030 PFY-VQSELTDWETPQNQARRSGISSFGAGGSNAHIIIEEYKNE 1072 Score = 451 bits (1161), Expect = e-124, Method: Compositional matrix adjust. Identities = 279/828 (33%), Positives = 432/828 (52%), Gaps = 92/828 (11%) Query: 5 RKPVPANPELLLELEKLGAQVMYAAVDVTSRAQMEELLARIHDVYGPLHGVIHAAGQMEY 64 + P+ + +LL EL++ G QV + +T + + + + +G + GVIH AG + Sbjct: 1518 KSPLYSKLQLLHELDQKGVQVEVYSGPLTEKETLHRFFSEVRLKFGKIGGVIHCAGAANH 1577 Query: 65 APHKLLTRSQDEIEQVLAPKWQGTIIADLVTRQEPLRFFAALSSVSASRKAWASGLGDYA 124 + + +S EI +V PK QG + + + L FF SSV+++ +G DYA Sbjct: 1578 SNPAFIHKSDQEIREVFEPKVQGMQVLHDIFIDDKLDFFILFSSVASAFPLLGAGTSDYA 1637 Query: 125 AANAFLNGYCIYRAGDNAPGRSL--SINYSLWKDTGAGTDFGRLVELALKGQGLQPLAHE 182 AANAF++ + Y+ +A GR+ SIN+ WKD G G + + + GL + E Sbjct: 1638 AANAFMDYFAAYQ---HAAGRTYYQSINWPSWKDIG----MGEVTSPSYQALGLLSHSTE 1690 Query: 183 AAAAVFLRALSSPGSDIVHVLDLVEPKAHKEAFALPP---SRQEPARL---AEQKFIHRS 236 A+ ++ G L+ K H E F L +R + A+ AE+K I Sbjct: 1691 TGIAMLDEMMTINGYPC-----LIPAKTHPEKFKLQQLLQTRIQAAKNNPDAEEKVISGQ 1745 Query: 237 ARE---IRDIVYQAIGEELRISVRHLETGMNFTELGLDSVGATRVVADIGGKLGTELYPT 293 IR ++ + EL+I +L+ +F + G+DS+ ++V ++ P+ Sbjct: 1746 GDNEAIIRKLM-EIFSAELKIPCGNLDQDTSFADYGVDSILLVQLVKKAEDAFQIKIEPS 1804 Query: 294 LIFEYQTPEALASHIAE---------QLTEDSXXXXXXXXXXXXXXXXXXXXXRQ----- 339 EY + L ++ E Q+ ++ Q Sbjct: 1805 AFLEYPSFSQLGVYLNELFASEGISPQIDSENIEVRKKEQHINQNASEVRDSGSQIQQTS 1864 Query: 340 --DIAIIGMGLRIPGANSLEEYWELLYSGRSAIREVDPGRWSDDKHVNEDAGVFHTSYTG 397 IAIIGMG P A E +W L G++++REV RW D D S + Sbjct: 1865 LNQIAIIGMGCEFPDAPDTETFWTNLKKGQNSVREVPASRW-DISSYYSDTYEKGKSISK 1923 Query: 398 KGGFIDAPYDFDPLFFGMSPKEAESADPQQRIFLQICWEALQQAGYGGKYRTRK-IGVFA 456 GGF+ FDP FF M+ EA DP + L++ + L+ GY + + K +GVF Sbjct: 1924 WGGFLQDIESFDPAFFNMNKSEASELDPLIKKCLEVSVQTLRDGGYTKEEVSNKEVGVFI 1983 Query: 457 GCEQNTYMEHFANYRSYMLIKERLLDSPAFLGMLPAERQEILARISGVLEPARLVADVVA 516 G T+M S + P++ + + Sbjct: 1984 GSRTGTFM-------------------------------------SKIGSPSK---NTIV 2003 Query: 517 GNGLNEVAARVSHCLNLSGPSLIVNSACSSSLVAIHMACESLRTGQSEMALAGGVNLNLS 576 G G N + A +SH NL GP+L+V++ACSSS+V++H+AC+SL + +S+MA+AGGV++ L Sbjct: 2004 GIGQNFIGAHISHFFNLKGPNLVVDTACSSSVVSVHLACQSLMSKESDMAIAGGVDILLD 2063 Query: 577 PTPFVSLSRVTALSPTGECYPFDQRANGMVLGEGAGAVLLKPLHAALRDGDHIHAVIKGS 636 P+V LS ALSP G+C+ FD++A+G V GEG GAVLLK L AL +GD I+AVI S Sbjct: 2064 QKPYVMLSEARALSPEGKCHTFDEKADGFVPGEGCGAVLLKRLDDALAEGDRIYAVIDSS 2123 Query: 637 AVNNDGRSQGITAPRPQGQAEVIREAFVRTGIHPETVSYIETHGTATPLGDPIEIEGMTR 696 AVNNDG++ G+T P P+ Q+ VI++A + GI +T+SY+ETHGT T +GDPIE++ +T Sbjct: 2124 AVNNDGQTMGMTTPNPKAQSAVIKKALKKGGIDADTLSYVETHGTGTMIGDPIELKALTE 2183 Query: 697 AFSSFTDKKQFCGIGSVKSSVGHMLSAAGVTSLIKVVLSLKHQILPHTVNYEQPNPNIDF 756 F T++ QFCG+GSVK++ GH++SAAG+ S+IKV LS+K+Q+LP T++ + PNP F Sbjct: 2184 VFREVTEETQFCGVGSVKTNFGHLMSAAGIASIIKVALSIKNQMLPPTLHCKTPNPRFKF 2243 Query: 757 EHSPFY----VVDKHPRRWEAAGDAPLRASVNAFGFGGTNAHVILEQA 800 + SPF+ + + PR+ LRA +++FGFGGTNAH+IL + Sbjct: 2244 DQSPFFPNTSLKEWRPRK------GVLRAGISSFGFGGTNAHMILSDS 2285 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.135 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 7,017,803,429 Number of extensions: 308948824 Number of successful extensions: 762751 Number of sequences better than 1.0e-05: 10039 Number of HSP's gapped: 732444 Number of HSP's successfully gapped: 16731 Length of query: 1166 Length of database: 3,060,696,203 Length adjustment: 147 Effective length of query: 1019 Effective length of database: 1,675,806,998 Effective search space: 1707647330962 Effective search space used: 1707647330962 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 137 (57.4 bits)