BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0256.0023.p (313 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K778.1 B3K778_9BACI Ketopantoate reductase ApbA/PanE domain pr... 438 e-121 C0ZGP0.1 C0ZGP0_BREBN Putative uncharacterized protein 295 4e-78 Q97J15.1 Q97J15_CLOAB Ketopantoate reductase 237 9e-61 A8SH81.1 A8SH81_9FIRM Putative uncharacterized protein 194 7e-48 A8S8S9.1 A8S8S9_9FIRM Putative uncharacterized protein 186 2e-45 >B3K778.1 B3K778_9BACI Ketopantoate reductase ApbA/PanE domain protein Length = 315 Score = 438 bits (1126), Expect = e-121, Method: Compositional matrix adjust. Identities = 207/308 (67%), Positives = 253/308 (82%) Query: 1 MKILVYGAGVLGSYLAHVLVRGGNNVTMLARGARLDELQKHGNVIRHYFQFRTTADKVNV 60 M+ILVYGAGVLGSYLAH +VR G+NVTMLARG R +EL+K+GNVIRHYFQF+TT V V Sbjct: 1 MRILVYGAGVLGSYLAHEMVRVGHNVTMLARGQRANELEKNGNVIRHYFQFKTTVHNVRV 60 Query: 61 ISELQPEDIYDLVFVVMKYPDFHSVLPALAANHSSRVVLVGNNANPTEMRDYLQANSPVQ 120 I EL+P+D+YDL+FVVMKYPDF +VLPALAANHS VV++GNNA+P +M+ YLQA+S V Sbjct: 61 IRELEPDDVYDLIFVVMKYPDFEAVLPALAANHSRHVVIMGNNASPQDMQTYLQAHSSVT 120 Query: 121 KQVAFGFQVSAGWREPGRMFTVRGPQVQMTIGGLGEDLPWRTVIDQAFVNTKYKLVYHQN 180 KQVAF FQ AGWRE G + +VRGP+ ++ IGGLGEDL WR IDQA NTKY Y +N Sbjct: 121 KQVAFAFQSIAGWRENGLVISVRGPRTKINIGGLGEDLSWRPFIDQALANTKYAWTYQKN 180 Query: 181 MDEWLKSHFMMILPLNFIAPAHNGDLRKAAKDNKLLHQVIAAVDEGHQVLEKLGYTVTPA 240 M+EWLKSH++MIL LN IA A+NG+LR+AAKD KLLH VI A+DEGHQVLEK G+TVTPA Sbjct: 181 MNEWLKSHYVMILALNSIASAYNGNLRRAAKDRKLLHLVIHAMDEGHQVLEKNGFTVTPA 240 Query: 241 SQLKLARKQRKMFYIMLKIMLSTPVGKILLGDKAVSADEMSALYQAFIDLKSRAGIPTPN 300 +Q + ARK RK+FYI+LK+MLS P+ +ILL DKAVSA+E++AL QAF +LK A + TP+ Sbjct: 241 AQKQFARKNRKLFYILLKMMLSIPISRILLSDKAVSANEVTALQQAFAELKKSANMATPH 300 Query: 301 WDTLGIHS 308 WD L +S Sbjct: 301 WDELQQYS 308 >C0ZGP0.1 C0ZGP0_BREBN Putative uncharacterized protein Length = 308 Score = 295 bits (755), Expect = 4e-78, Method: Compositional matrix adjust. Identities = 144/304 (47%), Positives = 205/304 (67%), Gaps = 4/304 (1%) Query: 1 MKILVYGAGVLGSYLAHVLVRGGNNVTMLARGARLDELQKHGNVIRHYFQFRTTADKVNV 60 M ILVYGAGV GSYLA+VLV+GG++VT+LARG R +EL+K G VIRHY Q +TT D+V V Sbjct: 1 MNILVYGAGVQGSYLAYVLVKGGHDVTVLARGKRAEELEKEGLVIRHYLQRKTTIDRVRV 60 Query: 61 ISELQPEDIYDLVFVVMKYPDFHSVLPALAANHSSRVVLVGNNANPTEMRDYLQANSPVQ 120 I L+ D YDL+FV+MKY DF +VLP LA N S +VLVGNN + M+DYL + Sbjct: 61 IRRLESSDAYDLIFVMMKYSDFGAVLPILAENISRHIVLVGNNMDTYAMQDYLSKHGQSP 120 Query: 121 KQVAFGFQVSAGWREPGRMFTVRGPQVQMTIGGLGEDLPWRTVIDQAFVNTKYKLVYHQN 180 KQVAFGFQ +AG R GR+ +RG +M IGGL +P+R++++QAF+ TKYKL YH Sbjct: 121 KQVAFGFQATAGKRTDGRVICIRGGHGEMIIGGLDGPIPFRSLLEQAFMRTKYKLSYHDQ 180 Query: 181 MDEWLKSHFMMILPLNFIAPAHNGDLRKAAKDNKLLHQVIAAVDEGHQVLEKLGYTVTPA 240 +D WLK+H ++++P+N + H +++ +D++ + Q++A + EG +VL+ LGY +TP Sbjct: 181 IDAWLKNHMVLVVPMNMVILFHGFQMKQVVRDDRRMRQLVAGMGEGFRVLDSLGYPLTPP 240 Query: 241 SQLKLARKQRKMFYIMLKIMLSTPVGKILLGDKAVSADEMSALYQAFIDLKSRAGIPTPN 300 Q + + LKI PV ++ G +A E+ AL +AF + ++R+ +PTPN Sbjct: 241 EQASWITRYPNLIRWALKIFFMLPVSGLIDG----TAVELIALNEAFAEWRARSDVPTPN 296 Query: 301 WDTL 304 WD L Sbjct: 297 WDAL 300 >Q97J15.1 Q97J15_CLOAB Ketopantoate reductase Length = 319 Score = 237 bits (605), Expect = 9e-61, Method: Compositional matrix adjust. Identities = 127/309 (41%), Positives = 190/309 (61%), Gaps = 2/309 (0%) Query: 1 MKILVYGAGVLGSYLAHVLVRGGNNVTMLARGARLDELQKHGNVIRHYFQFRTTADKVNV 60 MKIL+YGAGVLGSY A+ L R G+ VT+LAR +R +EL++ G VIRH+FQ +TT +K+NV Sbjct: 1 MKILIYGAGVLGSYAAYELKRVGHEVTILARSSRYEELKEKGLVIRHWFQRKTTKNKINV 60 Query: 61 ISELQPEDIYDLVFVVMKYPDFHSVLPALAAN-HSSRVVLVGNNANPTEMRDYLQANSPV 119 + EL PE+ YD VF+VM+ +++LP + AN V VGN ++ + +++ S Sbjct: 61 VKELLPEEYYDAVFIVMQSSQTNAILPVITANVKCPLFVFVGNQDKAKDISEKIKSTSKS 120 Query: 120 QKQVAFGFQVSAGWREPGRMFTVRGPQVQMTIGGLGEDLPWRTVIDQAFVNTKYKLVYHQ 179 +V FGF G RE G++ +V IG L ++ +I++ F T +KL YH Sbjct: 121 NPRVLFGFFSIGGRREGGKVISVHTKHPDFDIGDLEGRDDYKIIIEKIFKETSFKLHYHV 180 Query: 180 NMDEWLKSHFMMILPLNFIAPAHNGDLRKAAKDNKLLHQVIAAVDEGHQVLEKLGYTVTP 239 NMD++ K+H ++I+PL ++A N DLRK A + K L+ VI A+ EGH+VL KLG+ V P Sbjct: 181 NMDDFFKTHIVVIMPLAYLAYMSNCDLRKIAWNRKALNAVIDAMIEGHEVLIKLGHKVDP 240 Query: 240 ASQLKLARKQRKMFYIMLKIMLSTPVGKILLGDKAVSA-DEMSALYQAFIDLKSRAGIPT 298 S +L R RK+ Y+ LK+ TP+GK+ + D S EM L + ++ ++ + T Sbjct: 241 ESSERLLRNHRKVAYLGLKVCAMTPLGKLGISDHCKSGWREMEYLDKRLLEWAKKSNLET 300 Query: 299 PNWDTLGIH 307 PN + L H Sbjct: 301 PNINKLREH 309 >A8SH81.1 A8SH81_9FIRM Putative uncharacterized protein Length = 308 Score = 194 bits (494), Expect = 7e-48, Method: Compositional matrix adjust. Identities = 113/306 (36%), Positives = 170/306 (55%), Gaps = 9/306 (2%) Query: 1 MKILVYGAGVLGSYLAHVLVRGGNNVTMLARGARLDELQKHGNVIRHYFQFRTTADKVNV 60 MKILVYGAGVLG LA L+R G +VT+LARG E++++G I+ F RT+ ++ V Sbjct: 1 MKILVYGAGVLGCNLARNLLRAGKDVTLLARGNWAAEIKQNGLRIKDKFSLRTSVSRIPV 60 Query: 61 ISELQPEDIYDLVFVVMKYPDFHSVLPALAANHSSRVVLVGNNANPTEMRDYLQANSPVQ 120 ++EL P+ +YD++FVV++Y SVL L AN + +V VGNN + A + + Sbjct: 61 VTELAPDAMYDVIFVVLRYTQLDSVLDTLRANRTKNIVFVGNNVQTKAL-----AAALPE 115 Query: 121 KQVAFGFQVSAGWREPGRMFTVRGPQVQMTIGGLGEDLPWRTVIDQAFVNTKYKLVYHQN 180 K V F F +SAG RE R+ ++ ++ TIG L + + +I + F TKYK+VY N Sbjct: 116 KNVLFAFALSAGHREVDRVVSIDLKKI--TIGQLPGAISNKQLIGRIFHGTKYKVVYEPN 173 Query: 181 MDEWLKSHFMMILPLNFIAPAHNGDLRKAAKDNKLLHQVIAAVDEGHQVLEKLGYTVTPA 240 M+++L H ++P F +GDL+K D L++V+ A EG++ + G+T+ P Sbjct: 174 MEDYLLCHAAFVMPAAFACYKTDGDLKKLRGDTAYLNRVLDANIEGYRAIRDAGHTILPK 233 Query: 241 SQLKL-ARKQRKMFYIMLKIMLSTPVGKILLGDKAVSA-DEMSALYQAFIDLKSRAGIPT 298 K RK K+M +T +GK+ D A++A DEMSAL + G Sbjct: 234 EDADFEGEKYRKTCLRFFKLMCATSLGKLCASDHAMNAIDEMSALNRDLKKFFDEHGAAY 293 Query: 299 PNWDTL 304 P W L Sbjct: 294 PVWQAL 299 >A8S8S9.1 A8S8S9_9FIRM Putative uncharacterized protein Length = 396 Score = 186 bits (473), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 110/306 (35%), Positives = 165/306 (53%), Gaps = 9/306 (2%) Query: 1 MKILVYGAGVLGSYLAHVLVRGGNNVTMLARGARLDELQKHGNVIRHYFQFRTTADKVNV 60 MKILVYGAGVLG LA L+R G NVT+LARG E++++G I+ F RT+ ++ V Sbjct: 89 MKILVYGAGVLGCNLARNLLRAGKNVTLLARGNWAAEIKQNGLRIKDKFSLRTSVSRIPV 148 Query: 61 ISELQPEDIYDLVFVVMKYPDFHSVLPALAANHSSRVVLVGNNANPTEMRDYLQANSPVQ 120 ++EL P+ +YD++FVV++Y S L L AN + +V VGNN + L Sbjct: 149 VTELAPDAMYDVIFVVLRYTRLDSALDTLRANRTKNIVFVGNNVQARALAAALPG----- 203 Query: 121 KQVAFGFQVSAGWREPGRMFTVRGPQVQMTIGGLGEDLPWRTVIDQAFVNTKYKLVYHQN 180 K V F F +SAG RE R+ ++ ++ TIG L + +I + F TKYK+VY N Sbjct: 204 KNVLFAFALSAGHREVDRVVSIDLKKI--TIGQLPGATSNKQLIGRIFHGTKYKVVYEPN 261 Query: 181 MDEWLKSHFMMILPLNFIAPAHNGDLRKAAKDNKLLHQVIAAVDEGHQVLEKLGYTVTPA 240 M+++L H ++P F +GDL+K D L++++ A EG++ + G+ + P Sbjct: 262 MEDYLLCHAAFVMPAAFACYKTDGDLKKLRGDTAYLNRLLDANIEGYRAIRNAGHAILPK 321 Query: 241 SQLKL-ARKQRKMFYIMLKIMLSTPVGKILLGDKAVSA-DEMSALYQAFIDLKSRAGIPT 298 K RK K+M +T +GK+ D A++A DEM+AL + G Sbjct: 322 EDADFEGEKYRKTCLRFFKLMCATSLGKLCASDHAMNAIDEMNALNRDLKKFFDANGAAY 381 Query: 299 PNWDTL 304 P W L Sbjct: 382 PVWQAL 387 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.322 0.137 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,832,954,377 Number of extensions: 72445451 Number of successful extensions: 207134 Number of sequences better than 1.0e-05: 29 Number of HSP's gapped: 207141 Number of HSP's successfully gapped: 29 Length of query: 313 Length of database: 3,060,696,203 Length adjustment: 135 Effective length of query: 178 Effective length of database: 1,788,859,178 Effective search space: 318416933684 Effective search space used: 318416933684 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 131 (55.1 bits)