BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0254.0020.p (416 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1D927.1 B1D927_9BACL Major facilitator superfamily MFS_1 355 4e-96 C2V5B5.1 C2V5B5_BACCE Major facilitator superfamily MFS_1 349 3e-94 C2U7Q6.1 C2U7Q6_BACCE Major facilitator superfamily MFS_1 348 6e-94 C2WWY8.1 C2WWY8_BACCE Major facilitator superfamily MFS_1 346 2e-93 C2X4Y0.1 C2X4Y0_BACCE Major facilitator superfamily MFS_1 345 4e-93 >B1D927.1 B1D927_9BACL Major facilitator superfamily MFS_1 Length = 397 Score = 355 bits (912), Expect = 4e-96, Method: Compositional matrix adjust. Identities = 195/388 (50%), Positives = 240/388 (61%), Gaps = 1/388 (0%) Query: 28 SKAVPGWITFLLAASCGLIVANLYYAQTLVGPISAATHLSSGAAGLIVTLTQIGYVIGLL 87 K +P W+T LLA +CG+I ANLYYAQ LVG IS++ LS+G+AGLIVTLTQIGYV+GLL Sbjct: 10 EKNIPAWLTILLATACGMIAANLYYAQPLVGLISSSIGLSAGSAGLIVTLTQIGYVVGLL 69 Query: 88 FVVPLSDIIENRRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIGLGSVAAQILVPYAS 147 F+VP+ DI+ENR+ IGLGSVAAQ+LVP+AS Sbjct: 70 FIVPMGDIVENRKLVITALLLTAVALITASLAKQSFLFLTATLVIGLGSVAAQVLVPFAS 129 Query: 148 YLAAEEHRGRVVGNVMSGLLLGIMFARPLASFVSGLWGWHAIFAISAVIIALLTILLSRV 207 YLA++ RGRVVGNVMSGLLLGIM ARP++S V+ +GWHAIFAISAV I +L I+L++V Sbjct: 130 YLASDASRGRVVGNVMSGLLLGIMLARPISSLVADFFGWHAIFAISAVAIVILAIVLAKV 189 Query: 208 LPKRQPIPTMNYGGLIRSLGTLLKTTPVLRRRALYQASLFGTFSLFWTTVSLRLA-DTYH 266 LP R+P +Y L+ S+ LL+TTP+LRRRALY A+LF FSLFWTTV LA +H Sbjct: 190 LPVRKPTAATSYTALLGSMWRLLRTTPILRRRALYHATLFAAFSLFWTTVPQLLAGPKFH 249 Query: 267 LSQQXXXXXXXXXXXXXXXXXXXXXXXDRGWTRPLTGXXXXXXXXXXXXXXXXQSDSKVT 326 SQ DRGWTRP T Q+ S V Sbjct: 250 FSQTAIALYALVGVAGAVAAPLAGRLADRGWTRPATAIALITVIVSVLLPLLIQTSSPVG 309 Query: 327 LGLLVVGAIILDMGVSGNLVLGQRAIYSLGNEARGRLNGLFMAIFFIGGAIXXXXXXXXX 386 + +LV+ AI+LD GVS NLVL QR+I+SLG + R RLNGLFMAIFF GGAI Sbjct: 310 VVVLVIAAILLDAGVSANLVLSQRSIFSLGADIRSRLNGLFMAIFFFGGAIGSAAGGWAY 369 Query: 387 XXXXXXXTTLIGLALPVLAFLYYLTEKK 414 +G+A P LA LY+ TE+K Sbjct: 370 AAGGWSSALWLGIAFPTLALLYFATERK 397 >C2V5B5.1 C2V5B5_BACCE Major facilitator superfamily MFS_1 Length = 396 Score = 349 bits (895), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 189/396 (47%), Positives = 240/396 (60%), Gaps = 1/396 (0%) Query: 19 VKHAQASAASKAVPGWITFLLAASCGLIVANLYYAQTLVGPISAATHLSSGAAGLIVTLT 78 + + + A +K + + LLA +CG+IVANLYYAQ L+G IS LS+ +AGLIVTLT Sbjct: 1 MSNFKNKAINKEISSGLIILLATACGIIVANLYYAQPLIGVISHVIGLSNSSAGLIVTLT 60 Query: 79 QIGYVIGLLFVVPLSDIIENRRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIGLGSVA 138 QIGYV+GLLF+VPL DI+ENR+ IGLGSVA Sbjct: 61 QIGYVVGLLFLVPLGDIVENRKLIIILLILSAVALTATVFVKSAILLLVASFFIGLGSVA 120 Query: 139 AQILVPYASYLAAEEHRGRVVGNVMSGLLLGIMFARPLASFVSGLWGWHAIFAISAVIIA 198 AQ+LVP+ SYL++E+ RGRVVGNVMSGLLLGIM ARP++S V+ +WGW+AIFA+SA +I Sbjct: 121 AQVLVPFVSYLSSEDARGRVVGNVMSGLLLGIMLARPISSLVADIWGWNAIFALSATVII 180 Query: 199 LLTILLSRVLPKRQPIPTMNYGGLIRSLGTLLKTTPVLRRRALYQASLFGTFSLFWTTVS 258 +L +LS+VLP R+P NY L+ S+ LL+TTP+LRRRA+Y A +FG FSLFWTTV Sbjct: 181 VLAFVLSKVLPTRKPTEKTNYTALLSSMWQLLRTTPILRRRAIYHACVFGAFSLFWTTVP 240 Query: 259 LRLAD-TYHLSQQXXXXXXXXXXXXXXXXXXXXXXXDRGWTRPLTGXXXXXXXXXXXXXX 317 L L+ +H SQ D GWTRP TG Sbjct: 241 LLLSSPAFHFSQTAIALYALVGITGAIAAPIGGRLADFGWTRPATGIALTVVIISLLLPL 300 Query: 318 XXQSDSKVTLGLLVVGAIILDMGVSGNLVLGQRAIYSLGNEARGRLNGLFMAIFFIGGAI 377 Q S + + +LV+ AI+LDMGVS NLVL QR I+SL E R RLNGLFMAIFF+GGA+ Sbjct: 301 IIQGSSPIGIAVLVIAAILLDMGVSANLVLSQRLIFSLDPEIRSRLNGLFMAIFFLGGAV 360 Query: 378 XXXXXXXXXXXXXXXXTTLIGLALPVLAFLYYLTEK 413 T IG+ P++A LY+ TEK Sbjct: 361 GSSLGGWAYALGGWSLTLWIGIPFPIIALLYFSTEK 396 >C2U7Q6.1 C2U7Q6_BACCE Major facilitator superfamily MFS_1 Length = 396 Score = 348 bits (893), Expect = 6e-94, Method: Compositional matrix adjust. Identities = 189/396 (47%), Positives = 240/396 (60%), Gaps = 1/396 (0%) Query: 19 VKHAQASAASKAVPGWITFLLAASCGLIVANLYYAQTLVGPISAATHLSSGAAGLIVTLT 78 + + + A +K + + LLA +CG+IVANLYYAQ L+G IS LS+ +AGLIVTLT Sbjct: 1 MSNFKNKAINKEISSGLIILLATACGIIVANLYYAQPLIGVISHVIGLSNSSAGLIVTLT 60 Query: 79 QIGYVIGLLFVVPLSDIIENRRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIGLGSVA 138 QIGYV+GLLF+VPL DI+ENR+ IGLGSVA Sbjct: 61 QIGYVVGLLFLVPLGDIVENRKLIIILLILSAVALTATVFVKSAILLLVASFFIGLGSVA 120 Query: 139 AQILVPYASYLAAEEHRGRVVGNVMSGLLLGIMFARPLASFVSGLWGWHAIFAISAVIIA 198 AQ+LVP+ SYL++E+ RGRVVGNVMSGLLLGIM ARP++S V+ +WGW+AIFA+SA +I Sbjct: 121 AQVLVPFVSYLSSEDARGRVVGNVMSGLLLGIMLARPISSLVADIWGWNAIFALSATVII 180 Query: 199 LLTILLSRVLPKRQPIPTMNYGGLIRSLGTLLKTTPVLRRRALYQASLFGTFSLFWTTVS 258 +L +LS+VLP R+P NY L+ S+ LL+TTP+LRRRA+Y A +FG FSLFWTTV Sbjct: 181 VLAFVLSKVLPTRKPTEKTNYTALLSSMWQLLRTTPILRRRAIYHACVFGAFSLFWTTVP 240 Query: 259 LRLAD-TYHLSQQXXXXXXXXXXXXXXXXXXXXXXXDRGWTRPLTGXXXXXXXXXXXXXX 317 L L+ +H SQ D GWTR TG Sbjct: 241 LLLSSPAFHFSQTAIALYALVGITGAIAAPIGGRLADFGWTRSATGIALTVVIISLLLPL 300 Query: 318 XXQSDSKVTLGLLVVGAIILDMGVSGNLVLGQRAIYSLGNEARGRLNGLFMAIFFIGGAI 377 Q S + + +LV+ AI+LDMGVS NLVL QR I+SL E R RLNGLFMAIFF+GGA+ Sbjct: 301 IIQGSSPIGIAVLVIAAILLDMGVSANLVLSQRLIFSLDPEIRSRLNGLFMAIFFLGGAV 360 Query: 378 XXXXXXXXXXXXXXXXTTLIGLALPVLAFLYYLTEK 413 T IG+A P++A LY+ TEK Sbjct: 361 GSSLGGWAYALGGWSLTLWIGIAFPIIALLYFSTEK 396 >C2WWY8.1 C2WWY8_BACCE Major facilitator superfamily MFS_1 Length = 401 Score = 346 bits (888), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 188/396 (47%), Positives = 239/396 (60%), Gaps = 1/396 (0%) Query: 19 VKHAQASAASKAVPGWITFLLAASCGLIVANLYYAQTLVGPISAATHLSSGAAGLIVTLT 78 + + + A+ K + + LLA +CG+IVANLYYAQ L+G IS LS+ +AGLIVTLT Sbjct: 6 MSNFKNKASDKEISSGLIILLATACGIIVANLYYAQPLIGVISNEIGLSNSSAGLIVTLT 65 Query: 79 QIGYVIGLLFVVPLSDIIENRRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIGLGSVA 138 QIGYV+GLLF+VPL DI+EN++ IGLGSVA Sbjct: 66 QIGYVVGLLFLVPLGDIVENKKLILILLFSSAFALISMVFVKSATLLLIASFFIGLGSVA 125 Query: 139 AQILVPYASYLAAEEHRGRVVGNVMSGLLLGIMFARPLASFVSGLWGWHAIFAISAVIIA 198 AQ+LVP SYL++E RGRVVGNVMSGLLLGIM ARP++S V+G+WGW+AIFA+S+ +I Sbjct: 126 AQVLVPLVSYLSSENTRGRVVGNVMSGLLLGIMLARPISSLVAGMWGWNAIFALSSTVII 185 Query: 199 LLTILLSRVLPKRQPIPTMNYGGLIRSLGTLLKTTPVLRRRALYQASLFGTFSLFWTTVS 258 +L +LS+VLP R+P NY L+ S+ LL+TTP+LRRRA+Y A +FG FSLFWTTV Sbjct: 186 VLAFVLSKVLPTRKPKAKTNYTTLLNSMWQLLRTTPILRRRAIYHACVFGAFSLFWTTVP 245 Query: 259 LRLAD-TYHLSQQXXXXXXXXXXXXXXXXXXXXXXXDRGWTRPLTGXXXXXXXXXXXXXX 317 L L+ +H SQ D GWTRP TG Sbjct: 246 LLLSSPAFHFSQTAIALYALVGITGAIAAPIGGRLADLGWTRPATGIVLTVVIISLLLPL 305 Query: 318 XXQSDSKVTLGLLVVGAIILDMGVSGNLVLGQRAIYSLGNEARGRLNGLFMAIFFIGGAI 377 +S S + + +LV+ AI+LDMGVS NLVL QR I+SL E R RLNGLFMAIFF+GGA+ Sbjct: 306 IIRSSSPIGIAVLVIAAILLDMGVSANLVLSQRLIFSLSPEIRSRLNGLFMAIFFLGGAV 365 Query: 378 XXXXXXXXXXXXXXXXTTLIGLALPVLAFLYYLTEK 413 T IG+ P +A LY+ TEK Sbjct: 366 GSFIGGWAYALGGWNLTLWIGITFPAIALLYFATEK 401 >C2X4Y0.1 C2X4Y0_BACCE Major facilitator superfamily MFS_1 Length = 396 Score = 345 bits (886), Expect = 4e-93, Method: Compositional matrix adjust. Identities = 188/396 (47%), Positives = 240/396 (60%), Gaps = 1/396 (0%) Query: 19 VKHAQASAASKAVPGWITFLLAASCGLIVANLYYAQTLVGPISAATHLSSGAAGLIVTLT 78 + + + A +K + + LLA +CG+IVANLYYAQ L+G IS LS+ +AGLIVTLT Sbjct: 1 MSNFKNKAINKEISSGLIILLATACGIIVANLYYAQPLIGVISHVIGLSNSSAGLIVTLT 60 Query: 79 QIGYVIGLLFVVPLSDIIENRRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIGLGSVA 138 QIGYV+GLLF+VPL DI+ENR+ IGLGSVA Sbjct: 61 QIGYVVGLLFLVPLGDIVENRKLIIILLILSAVALTATVFVKSAILLLVASFFIGLGSVA 120 Query: 139 AQILVPYASYLAAEEHRGRVVGNVMSGLLLGIMFARPLASFVSGLWGWHAIFAISAVIIA 198 AQ+LVP+ SYL++E+ RGRVVGNVMSGLLLGIM ARP++S V+ +WGW+AIFA+SA +I Sbjct: 121 AQVLVPFVSYLSSEDARGRVVGNVMSGLLLGIMLARPISSLVADIWGWNAIFALSATVII 180 Query: 199 LLTILLSRVLPKRQPIPTMNYGGLIRSLGTLLKTTPVLRRRALYQASLFGTFSLFWTTVS 258 +L +LS+VLP R+P NY L+ S+ LL+TTP+LRRRA+Y A +FG FSLFWTTV Sbjct: 181 VLAFVLSKVLPTRKPTEKTNYTTLLSSMWQLLRTTPILRRRAIYHACVFGAFSLFWTTVP 240 Query: 259 LRLAD-TYHLSQQXXXXXXXXXXXXXXXXXXXXXXXDRGWTRPLTGXXXXXXXXXXXXXX 317 L L+ +H SQ D GWTR TG Sbjct: 241 LLLSSPAFHFSQTAIALYALVGITGAIAAPIGGRLADFGWTRSATGIALTIVIISLLLPL 300 Query: 318 XXQSDSKVTLGLLVVGAIILDMGVSGNLVLGQRAIYSLGNEARGRLNGLFMAIFFIGGAI 377 Q S + + +LV+ AI+LDMGVS NLVL QR ++SL E R RLNGLFMAIFF+GGA+ Sbjct: 301 IIQGSSPIGIAVLVIAAILLDMGVSANLVLSQRLLFSLDPEIRSRLNGLFMAIFFLGGAV 360 Query: 378 XXXXXXXXXXXXXXXXTTLIGLALPVLAFLYYLTEK 413 T IG+A P++A LY+ TEK Sbjct: 361 GSSLGGWAYALGGWSLTLWIGIAFPIIALLYFSTEK 396 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.325 0.139 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,774,753,992 Number of extensions: 58759227 Number of successful extensions: 254038 Number of sequences better than 1.0e-05: 752 Number of HSP's gapped: 252709 Number of HSP's successfully gapped: 794 Length of query: 416 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 278 Effective length of database: 1,760,596,133 Effective search space: 489445724974 Effective search space used: 489445724974 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 132 (55.5 bits)